Langerin: nyocha banyere ọgwụ, ọnụahịa, ntuziaka

maka ọgwụgwọ

dyucha recvina: metformine

Langerin 500: Mbadamba ụrọ nke metformin hydrochloride 500 mg, nke ruru 390 mg metformin,

Langerin 850: 1 mbadamba mmiri nke methyl metformin hydrochloride 850 mg, nke ruru 662.9 mg metformin,

Langerin 1000: Mbadamba 1 nke metformin hydrochloride 1000 mg, nke ya na 780 mg metformin,

ọzọ mkpụrụokwu: stodi nke sodium, mmiri 40, mmiri mmiri silicic acid, ahịhịa ọka, magnesium stearate, ọka balium Sepifilm bilium 752 (hypromellose, macrogol-2000-monostearate, titanium dioxide), macrogol.

Lidị Likarska. Mbadamba ụrọ, n'ime shei.

Ndị na-ere ọgwụ. Antidiabetic nsogbu. Agụụ nke ihu abụọ. A10BA02 PBX koodu.

- Insulonezonezhniy Tsukrov ọrịa shuga ụdị II, ọ bụrụ na riven zucchar n'ọbara abụghị pidtrimuvati nke ọma erughị dyutoy, ikike anụ ahụ na ala masi tila,

- yana insulin - n'ụdị ụdị ọrịa ụbụrụ nke ọrịa ụbụrụ, enwere oke mgbatị elu nke nzọụkwụ dị elu, wee buruzie ọgụ nke abụọ na insulin.

Ọrịa shuga keto acidosis, precca shuga na shuga,

ọrụ nirok,

Gostrіi zhvoryuvannya, scho igry іz іz rіzіkom mmepe nke ọnwụ nke ọrụ nirok: akpịrị ịkpọ nkụ (ọ bụrụ na ọnya, ọbara), ihe egwu, іnfektsііnі zhvoryuvannya, bepụ, sepsis,

Ihe ngosi putara ihe banyere ulo ogwu na aka oru, nke puru iduba uto nke hypoxia (oria bu enweghi nri dichromic, infaksion gostrii myocardial),

ezigbo ịwa ahụ na mmerụ ahụ (ọ bụrụ na ọ dị mkpa, emere ọgwụgwọ ọgwụ),

arụmọrụ arụmọrụ

egbu egbu na-egbu egbu, gostre otruєnny mmanya,

mmetụta maka metformin ma ọ bụ ihe ndị dị n'ọgwụ ahụ,

nwoke na afọ ara,

lactic acidosis (gụnyere akụkọ ihe mere eme),

dotrimannya gіpokalorіyno dієti (erughị 1000zh 1000 cal / ext),

nwatakịrị wik ruo 10 nkume.

A naghị atụ aro ya ka ọ kpagide Langerin na mmadụ karịa afọ 60, onye nwere ike inwe ahụike dị mma, nke dị mkpa iji zụlite acid acid n'ime ha.

Sposib zososuvannya na dozi.

Overmụaka karịrị afọ iri

Mono ọgwụ yana ijikọ mkpuchi

Pochatkova nkwakọba doseє 1 mbadamba 500 mg ma ọ bụ 850 mg 1 oge kwa dob. Mgbe ụbọchị 10-15 gachara, a na-egosipụta ọ̀tụ̀tụ̀ corigovati na-esote ruo mgbe ọkwa glucose ọbara dị. Povіlnee pіdvishchenny dosuvannya na-agbada ugboro ole ọ na-enwe mmetụta n'akụkụ akụkụ eriri afọ.

Ihe kacha dobova bụ 2000 mg (rosodiene maka 2-3 priyomi).

Mono ọgwụgwọ yana agwakọta na ọgwụ antidiabetic nke ọnụ

Pochatkova dose to Langerin n'ụlọ nkwakọba ihe 500 mg 2-3 ugboro kwa doba ma ọ bụ 850 mg 2 ugboro kwa doba. Mgbe ụbọchị 10-15 gachara, a na-egosipụta ọ̀tụ̀tụ̀ corigovati na-esote ruo mgbe ọkwa glucose ọbara dị. Ọgwụ dị elu nwere ike belata ugboro ole nsonaazụ yana akụkụ akụkụ eriri afọ.

Ihe kacha dobova bụ 3000 mg.

N’oge ntughari na nchịkwa ọnụ ọgwụ mbu, gwọọ ọgwụ ọzọ n’oge ọzọ ọ dị m mkpa idozi nnyefe nri ahụ buru amụma na iji metformin.

Njikọ ya na insulin

Iji nweta obere nchịkwa nke glikemії, enwere ike idozi metformin na onye na-ejikọ ọnụ. Zvichain pochatkova dose Langerin nkwakọba ск 500 abo 850 mg 2-3 ugboro kwa oge, n'oge awa ahụ, m nwere ike ị aụ ọgwụ insulin tupu glucose ọbara.

Nkewa nke uwa

Vrakhovuchi ikike iwetula ọnụ ọgụgụ nke ndị ọrụ n’ime ndị ọrịa nwere obere metformin ka egosipụtara dị ka ihe ziri ezi ruo mgbe ọrụ nickel ahụ rụpụtara. Ọ dị mkpa ịtụle ọrụ nke nirok mgbe niile.

E gosipụtara obere ọgwụgwọ site na nhịahụ na nkwụsị nke ọdịdọ.

Were ogwu, were ya, were ya, chere otu ụbọchị, ma ọ bụ were ya.

Mmeghachi omume Pobichny.Mebiri emebi na akụkụ nke slag-eriri afọ tract: ọgbụgbọ, blues, "metal" na -eme n’ọnụ, afọ mgbu, agụụ, flatulence, afọ ọsịsa, mgbu afọ. Ihe mgbaàmà ahụ na-apụkarị n'oge mmiri, yana dịka iwu, ha na-ama onwe ha. Ihe mgbaàmà ndị a gbanwere na antacid, atopic atropine, na spasmolytic. Iji mee ka mmụọ ahụ pụọ na nsonaazụ ndị a, a na-atụ aro ka ịmalite ọgwụ ahụ ruo ọkara elekere, ma ọ bụ opekata mpe ugboro abụọ 2-3. Yakshcho ọrịa dyspeptik __, lіkuvannya ọgwụ slіd priniti.

Mebiri emebi na akụkụ obmіnu rechovin: lactic acid dyatez (M ga-achọ vіdmіni lіkuvannya), na obere lіkuvannі - gіpovіtamіnoz V₁₂ (dara na mgbe niile).

Mebiri emebi n'akụkụ akụkụ ọbara: na okremich vipadakh - anaemia bu megaloblastic.

Mmeghachi omume nfụkasị ahụ: Visip ka shkіrі.

Dodoụbiga ya ókè. Na metastasis metformin na kilogram 85 g, mmepe nke hypoglycemia emeghị nke ọma. Ale na tsyuyu vipadka gbanyere mkpọrọgwụ lactic acidosis. Mgbaàmà mbido nke lactic acidosis bụ ọgbụgbọ, blues, afọ ọsịsa, okpomoku mụbara, afọ, afọ na mummy, n’iru mmadụ nwere ike banye n’ọgba aghara, mebie ikuku na ihe ọchị.

Likuvannya: apụta na vipadok nwere akara nke lactic acidosis nke ọgwụ, ịchọrọ ịtụtụ ya, nwee ezigbo ụlọ ọgwụ thermo-hospital, na-egosi ịba ụba nke lactate, kọwaa nchoputa ya. Naybilsh n'ụzọ dị irè na iwebata Organic lactate na nkwadebe препара hemodialysis. Na-eduzi lіkuvannya symptomatic.

Zastosuvannya n'oge vaginosti abo nke ara. Ọ bụrụ na ịzubela ọgwụ vaginosti, ma nwee vipad, na vaginostnosti na azụlite ị takingụ ọgwụ, ịkwesịrị icheta ma gosipụta ọgwụ insulin. Nne na ụmụ amụrụ ọhụrụ na-akpachapụ anya.

Atụmatụ zastosuvannya. Dịka iwu, onye ọrịa ahụ nwere ọfụma, afọ mgbu, afọ mgbu, adịghị ike siri ike ma gbasie ike na-enweghị ngwakọ, mgbe ahụ ana m akpọrọ Langerin n'olu. Nyere mgbaàmà ndị a, ị nwere ike nweta ezigbo ihu na ntị nke lactic acidosis.

Afọ 48 tupu afọ 48, mgbe a gbasasịrị foto X-ray (fotography, vennum), ọgwụ ọzọ ga-ewere.

N'otu aka ahụ metforminom gbara afọ iri anọ na asatọ tupu arụ ọrụ hrurgicheskoe ịbanye na ọgwụ izizi yana ịmaliteghachi mbido afọ 48 ka emechara hrurgicheskoy gasịrị.

Langerin abụghị mmanya kachasị mma maka mmanya.

Achọrọ ahụike iji bulie ọsọ ọsọ mgbe ị na-eji ụgbọ njem akpaaka n'ụzọ ọ bụla. Langerin abụghị ihe kpatara hypoglycaemia, nke bụ naanị ihe kpatara mgbaghoju n'ọhụụ nke ọgwụgwọ anụ ahụ. Ọ bụrụ na afọ ojuju na ihe ndị dị oke mkpa dị (insulin, ọgwụ ndị na-arịa ọrịa shuga, sulfonialase na repaglination ka mma), ị nwere ike ịga n'ihu na metforminosis. Kwee ka ị nweta dyalnost na-ezighi ezi, dịka oke ọsọ nke mgbagha uche na nke anụ ahụ, ịnakwere mkpebi ngwa ngwa (dịka ọmụmaatụ, ilekọta nsogbu nsogbu njem, inyefe ụgbọala na ọrụ, mgbe ahụ ọrụ).

Njikọ ya na taabụ kacha mkpa ma hụ mgbanwe. Enweghị ntuziaka n’abali primenom danazolu maka giperglіkemіchno dії pụrụ iche fọdụrụ. Ọ bụrụ na ịchọrọ inye Danazol ma weghachite dose ahụ, were ụzọ ziri ezi nke ọgwụ ahụ si jiri njikwa glitch ndị ọzọ.

Alcoholakingụ mmanya na-aba n'anya na-enyere aka ịmalite lictic acidosis n'oge awa nke ị intoụbiga mmanya na-egbu egbu, karịchaa na agụụ agụụ, mana na mgbakwunye ụkọ calorie, yana nsogbu adịghị. Otu awa ka priyomuyu ọgwụ slіd unikati priyyu mmanya і lіkarskikh zasobіv, ọkà na-abọ ọbọ na mmanya.

Ngwakọta ndị chọrọ nlekọta pụrụ iche

Chlorpromazine: mgbe m na-a inụ nnukwu ọgwụ (100 mg kwa dob), m na-ewere glіkemіy, na-ebelata insulin. Maka ụdị ọgwụ mgbochi na ọgwụ, aga m ejikwa ọgwụ ndị ọzọ weghachite ezumike ndị ọzọ.

Glucocorticosteroid (GCS) na usoro na obere oge na-anabata nnabata glucose, mụbaa nri glutemia, yana mgbochi ketosis. Ọ bụrụ na ịnwere GCS, m na-edekwa ka ị were ọgwụ ndị ọzọ, mezie dose ahụ site na iji njikwa nke GLI.

Duretics: nnabata otu elekere nke loop dyuretics nwere ike ibute mmepe nke lactic acidosis site na oke erughi maliru nirkov.

Yodvmіsnі rediocontrast okwu: Nchoputa ihe nchoputa nke ihe ngbu x-ray nwere ike ibute lactic acidosis n’onodu ndi mmadu n’aria oria, n’iru oria oria. Jide ọgwụ ahụ afọ gara aga afọ 48 tupu ị nwee ahụ ike tupu afọ iri 48 mgbe nyochachara redio nke afọ gara aga na rediopaque rechinov.

A họpụtara ya na viglyad інєкційєкцій b₂nnabata: Kwalite Nkọwa nke mkpali mkpali b₂-receptor. Na tsyomu vipad potroben akara glikemії. Ọ bụrụ na ọ dị mkpa, a na-atụ aro ịhọpụta ka akwadoro

Site na iji otu oge ọgwụ dechara nke ikpeazụ sulfonylsechovini, insulin, acarbozoy, salicylates, ị nwere ike iwusi ya ike.

Ndị ọchịchị ọgwụ.Mlọ ọgwụ. Metformin - nke buru ibu nke nwere mmetụta mgbochi hyperglycemic, nke pụtara m belata hyperglycemia, anaghị eduga na mmepe nke hyperglycemic. Anaghị m akpali insulin insulin na anaghị m eme mmerụ ahụ na mmetụta dị mma na ndị mmadụ nwere ahụ ike.

Metformin pidvishchu na-anabata ndị na - anabata ihe na - eme insulin na iji glucose site na clitins. Upovlennyu gluconeogenesis na imeju. Aga m azọpịa carbohydrate niile na eriri afọ. Syringing mmetụta dị mma na metabolism nke lipids: Enwere m ikike dị ala iji gbanye cholesterol, yana ọkwa cholesterol dị ala na atọ glycerides.

Mlọ ọgwụ. Mgbe metastasis na-anabata mmiri n'ime eriri afọ, a na-ahụkarị ya, na ọnya, 20-30% nke dose ahụ. Zuru oke bioavailability nke ịbụ 50% na 60%. Site na nnabata nke otu oge, a na-ebelata metformin ma dozie.

Metformin shvidko rozpodilyaetsya na anụ ahụ, ọ bụ ihe bara uru ịghara itinye aka na plasmas protein. Metabolism metformin bụ enweghị udo na idu nirka.

Nirkovy klirens metformin ghọrọ> 400 ml / hv. Maka ndị chọrọ iji klọb ahụ mee ihe, klọb maka nzacha dị ịtụnanya na nzacha nzuzo. Kintseviy oge na pіvzhitty pіslya nchịkwa na nkwakọba ihe metformіnu ihe dị ka 6.5 afọ.

Site na nirkov funktsion gbajiri nirkov klirens metformіnu belatara n'ụzọ kwekọrọ na klirensu ọhụụ. Oge a ga-erute eruba, ọkwa nke metformin na plasma zrosta.

Ike anụ ahụ na kemịkal:

Langerin 500: bіlі gburugburuі, mbadamba biconvex, n'ime shei,

Langerin 850: Mbadamba bilium nke osisi, n'ime shei, na-enwe ihe ize ndụ site n'otu akụkụ,

Langerin 1000: mbadamba bilі oval, n'ime shei ahụ, na-enwe ihe ize ndụ site n'akụkụ abụọ.

Termin nke mgbakwunye. 3 nkume.

Ghichaa zberigannya. Agaghị m achọ uche pụrụ iche zberigannya. Zberigati nke ụmụ adịghị eru.

Mbukota. 10 mbadamba ụrọ maka ọnya, 3 maka 6 nke ọ bụla, ma ọ bụ 9 maka 9 ọnya.

Otu vіdpusku. Maka Ntụziaka.

Virobnik. NA "Zentiva".

Сцезнаходження. Нітрянська, 100, 920 27 Hlohovec, Slovak Republic.

Ngwongwo ọgwụ na ihe ngosi maka ojiji

Usoro ihe omume nke akụkụ ahụ dị mkpa nke ọgwụ ahụ jikọtara ya na ikike ya ịkwụsị mmechi nke gluconeogenesis, yana usoro njikọta nke abụba n'efu na oxidation abụba n'efu. Onye na-anọchite klas biguanide emetụtaghị insulin ewepụtara n'ime ọbara, kama ọ na-agbanwe ọgwụ ọgwụ ya site na ibelata ogo insulin na-ejedebe na ịba ụba nke insulin na proinsulin.

Isi ihe dị mkpa na usoro nke mbadamba ihe ndị dị otú a bụ mkpali nke glucose na-eme n’ihu site na mkpụrụ ndụ akwara.

Isi ihe na-egosi maka iji ọgwụ bụ mmepe nke ọrịa shuga na-akpata insulin na mmadụ, ọkachasị enweghị ike nke nri sochiri.

Njirimara ọgwụ ọgwụ dị na Langerin gụnyere:

• na -ewelata ego nke gemoclobinꓼ glycated
• na - egbochi insulin na - egbochi sel nke ọgwụ na insulin homonụ
• ọfụma na-emetụta oke iwu nke profaịlụ akwara nke plasmaꓼ ọbara
• belata cholesterolꓼ nke ojoo

Na mgbakwunye, iji ọgwụ ahụ eme ihe nwere ike ịbelata oke ahụ.

Ntuziaka maka mbadamba mbadamba

Ọgwụ Langerin dị n'ụdị nke mbadamba mkpuchi.

Mbadamba mbadamba ndị ahụ na akpa rọba, nke a na-eji ihe mkpuchi nke aluminom ekpuchi.

A na-etinye akwa n'ime igbe kaadi na ntuziaka maka ojiji nke ọgwụ.

Dabere n’usoro ọgwụ ịchọrọ iji mee ihe, a pụrụ iji ọgwụ were zụta ọgwụ a:

1. 500 milligrams.
2. Milligrams 850.
3. Otu gram nke ihe na-arụ ọrụ.

Ofzọ isi were mbadamba nkume ahụ bụ okwu ọnụ, n'oge nri ma ọ bụ mgbe ọ gachara. Dọkịta na-aga ya depụtara usoro ịgwọ ọrịa maka onye ọrịa ọ bụla n'otu n'otu dabere ogo ọrịa ahụ. Ọzọkwa, ọkachamara n’ihe banyere ọgwụ na-ekpebi ọnụọgụ ọgwụ ole n’otu ọgwụ n’ụbọchị.

Ntụziaka Langerin maka iji mee ihe na-atụ aro ịmalite usoro ọgwụgwọ ọgwụgwọ site na iji obere nke 500 mg nke ọgwụ na-arụ ọrụ. Ọnụ ọgụgụ nke ọgwụ mgbe ụbọchị nwere ike ịbụ otu ruo atọ. Nke nta nke nta, usoro onodi ogwu nwere ike ibuwanye 850 mg nke ihe eji arụ ọrụ ụbọchị dum (otu ugboro ugboro abụọ n'ụbọchị). Dọkịta na-aga ahụ na-enyocha ọnọdụ onye ọrịa ma ọ bụghị ihe karịrị otu ugboro n'izu, na-edozigharị ọnụọgụ ọgwụ agbagoro elu.

Edekwa ọgwụ a maka ịgwọ ọrịa ahụ na ụmụaka karịa afọ iri. Monotherapy kwesịrị ịmalite site na iji ọgwụ nke 500 mg nke ihe ahụ na-arụ ọrụ otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị. Mgbe oge ụfọdụ gasịrị, a na-ekwe ka mmụba nke ọgwụ ahụ nwayọ nwayọ, ma ọ dịghị karịa gram abụọ kwa ụbọchị, kewara abụọ ma ọ bụ atọ.

Dị ka ọ na-adị, mgbanwe n’usoro nke ọgwụ a na-apụta mgbe ụbọchị iri ruo ụbọchị iri na ise dabere na nsonaazụ nyocha ọbara maka ọkwa glucose.

N'ọnọdụ ụfọdụ, ịkwadebe mbadamba ụrọ bụ akụkụ nke ọgwụ ngwakọta na inje insulin.

Okwesiri iburu n'uche na a na-ahụta ochichi nke Langerin nwere insulin, ihe ndị na-eme ka sulfonylurea, acarbose, ma ọ bụ ndị na-egbochi ACE iji mee ka mmetụta hypoglycemic nke ọgwụ ahụ dịkwuo elu.

N'ọnọdụ ụfọdụ, dibịa na-aga ahụ nwere ike iji mbadamba ihe mebere ụdị dochie iji Langerin. Taa, enwere ọgwụ dị ukwuu, ihe bụ isi ọrụ ya bụ metformin.

Ọnụahịa ọgwụ analog nwere ike ịdị iche iche, dabere na ụlọ ọrụ ndị na-emepụta ọgwụ.

Kedu ihe bụ contraindications maka ojiji?

Usoro ọgwụgwọ ahọpụtara n'ụzọ na-ezighi ezi ma ọ bụ na-agbasoghị ndụmọdụ nke dibịa na-aga nwere ike ịkpasu ọdịdị nke mmeghachi omume ọjọọ mgbe ị na-a theụ ọgwụ ahụ.

Na mgbakwunye, enwere oge enwere iji iwu ọgwụ megide metformin amachibidoro.

Ntuziaka maka iji ọgwụ ahụ na-egosi ndepụta nke contraindications bụ isi.

Ihe ndi ozo banyere ojiji nke mbadamba Langerin bu ihe ndi a:

• oke nrụrụ imeju ma ọ bụ ọrụ akụrụ, ụkọ ha
• ahoụrụma, gụnyere n'ụdị na-adịghị ala ala
• obi ma ọ bụ iku ume ọdịda
• nnukwu myocardial infarctionꓼ
• Ọnọdụ akpịrị na-arịa ọrịa shuga ma ọ bụ nna nna
• mmepe nke ọrịa mamịrị ụkwụ na-arịa ọrịa shuga
• na ọnụnọ nke nnabata nke mmadụ na metformin yana mmepe nke mmeghachi ahụ nfụkasị ahụ
• ọnụnọ nke ọrịa na-efe efeꓼ
• na-ebu ọnụ na-arịa ọrịa shuga ma ọ bụ na-eso nri nri nke nri ya kwa ụbọchị anaghị aga otu puku kilocaloriesꓼ
• tupu yana mgbe a gbasịrị yaꓼ
• ya na mmerụ ahụ buru ibu na nso nso a
• tupu na mgbe nchọpụta ọrịa na-eji redioaktiiki isotropes nke ayodiin
• ketoacidosis na lactic acidosis.

Na mgbakwunye, ụmụ nwanyị ekwesịghị ị theụ ọgwụ ahụ n'oge ime na lact.

Ihe omume nwere ike ime n'akụkụ akụkụ ahụ na sisitemu nke ahụ mmadụ - eriri afọ, akwara ozi, akwara obi, akpụkpọ ahụ. Ihe mmeghachi omume kachasị njọ nke nwere ike ịme n'ihi ị theụ ọgwụ bụ:

1. Egwuregwu dị elu. Oge ụfọdụ ọgbụgbọ na-apụta n'ụdị ọrịa shuga 2. Enwere ike dochie ọgbụgbọ site na ọgbụgbọ.
2. Typedị afọ na-egbu mgbu.
3. Ntughari nke ihe otite n’ime onu.
4. Hematopoiesis na hemostasis.
5. Megaloblastic anaemia.
6. Mbelata shuga dị n'ọbara n'okpuru ọkwa a na-anabata nke ọma - hypoglycemia.
7. Ọdịdị nke adịghị ike n’anụ ahụ.
8. Rowsjọ.
9. Hypotension.
10. Ọrịa akụkụ iku ume.
11. Ọdịdị nke dermatitis ma ọ bụ ihe ọkụ ọkụ na anụahụ.

Ekwesịrị ịkpachara anya mgbe ị na-ewere Langerin na ọgwụ ndị ọzọ. Otu mbadamba osisi na cymeditine n’otu oge na-ebulite ohere nke lactic acidosis. Nchikota nke Langerin na akwara loop, nwere ike imeputa otu ihe ahu. N'okwu a, na mgbakwunye na enwere ike igosipụta lactic acidosis, enwere ike ịhụ ngosipụta nke ọdịda akụrụ.

N'iji ọgwụ ọjọọ eme ihe, ọ dị mkpa iji nyochaa arụmọrụ akụrụ dị mma ma chọpụta ego nke lactate na plasma ọbụlagodi ugboro abụọ n'afọ.

Enyere ozi banyere ọgwụ ndị e ji agwọ ọrịa shuga na vidiyo dị n'isiokwu a.

International Nonproprietary Aha

Aha mba ụwa dabara n'aha nke nọ n'ọrụ - Metformin (metformin).

A na-eji Langerin belata shuga ọbara.

Koodu ATX bu nọmba A10BA02.

Weputara udi ya na ihe mebere ya

Ọgwụ a dị naanị n'ụdị mbadamba maka nchịkwa ọnụ. A na-ahụ ụdị ndị dị iche iche - mkpuchi siri ike, ime ogologo oge, kpuchie ya na fim ahụ, ya na akwa mkpuchi.

Ihe bụ isi na-arụ ọrụ bụ metformin hydrochloride. Ndị na-ahụ maka ihe dị ugbu a: stachi ọka, magnesium stearate, macrogol 6000, anhydrous colloidal silicon dioxide, povidone 40, titanium dioxide, stodi sodium glycolate, hypromellose, monostearate-2000-macrogol.

Mlọ ọgwụ

Mgbe ị na-a theụ ọgwụ ahụ n’ime, a na-adọta metformin kpamkpam na traktị ahụ, ebe ihe ruru otu ụzọ n’ụzọ atọ na-ewepụta ahụ n’arụ. Oke ruru ịta ahụ ruru ka elekere abụọ na ọkara gachara. N'ime ọbara, ọgwụ a anaghị emekọ njikọ na protein; n'ime cytoplasm nke sel sel ọbara, akụrụngwa na-arụ ọrụ na-agbakọta n'ụdị nsogbu dị iche iche.

Ihe ruru otu ụzọ n'ụzọ atọ nke ọgwụ a na-apụ apụ na ahụ.

Ihe ngbanwe

Amachibidoro Metformin maka iji ụdị ndị a:

• hypersensitivity na mmiri,
• ya na oke akụrụ na oke arụ ọrụ.
• ahoụrụma,
• ọrịa na-efe efe na usoro obi,
• ụdị acidosis dị iche iche,
• ime na lactation
• na iji ayodiin iche,
• ụnwụ na akpịrị ụkpa.

Otu esi ewere Langerin

A na-a drugụ ọgwụ ahụ site na nyochaa ọkwa nke glucose dị n'ọbara, nke onye ọrịa kwesịrị ị tụọ ọtụtụ oge n'ụbọchị: n'ụtụtụ, mgbe nri ọ bụla, na mgbede tupu ị lakpuo ụra.

N'ikuku - n'ọnụ ka ị na-eri nri ma ọ bụ mgbe ọ gachara. Usoro izizi sitere na 500 mg ruo 850 2 ma ọ bụ ugboro atọ kwa ụbọchị. Mgbe izu abụọ gasị, ekwesịrị idozi dose ahụ dịka nsonaazụ nyocha glycemic si dị.

Oke kachasị agaghị enwe ike karịa 3000 mg, a na-ekewa ya ugboro atọ.

Maka ụmụaka mgbe afọ 10 gasịrị, usoro ọgwụgwọ ahụ bụ 500-850 mg kwa ụbọchị 1 oge. Oke kachasị bụ 2000 mg, kewara ugboro abụọ.

Na-arịa ọrịa shuga

Ntụziaka maka ojiji na-ekewa ọgwụgwọ ahụ n'ime monotherapy yana ijikọ insulin. Ọgwụ mbụ bụ 500-850 mg ugboro abụọ kwa ụbọchị na mgbe nri. Izu abụọ ka e mesịrị, a na-eme mgbanwe usoro ọgwụgwọ dabere na nsonaazụ shuga. N'oge a niile, onye ọrịa ahụ ga-enwerịrị profaịlụ glycemic. Ogo kachasị akwadoro bụ 3 g, kewara 3.

Na ọrịa shuga mellitus, ntuziaka maka ị drugụ ọgwụ ahụ kewara ọgwụgwọ ahụ n'ime monotherapy yana njikọ yana insulin.

Nsonaazụ Langerin

Ihe ojoo sitere na aru na sisitemu di iche iche nwere ike itolite.

1. Akpukpo aru: ihe okpukpo okpukpo, hives.
2. Mmetụta sistemụ ịba ọcha n'anya: ịba ọcha n'anya, ọrụ imeju na-arụ ọrụ.
3. Mgbaàmà nke akwara ozi: ọrịa uto.
4. Site na ngwara nri: mmetụta nke ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, enweghị agụụ, mgbu afọ, ịmị ọnụ, ọnụ nke ọla dị n'ọnụ.
5. N’oge na-adịghị anya, enwere mgbanwe na ọbara - megaloblastic anaemia, ụkọ vitamin B12.

Ngosiputa nke ulo ogwu na-achokwa onwe ha ma ewepu ogwu. N'ọnọdụ ndị a na-adịghị ahụkebe, a chọrọ usoro ọgwụgwọ Symptomatic.

Ntụziaka pụrụ iche

Ha na-edozigharị ọnụọgụ (mgbe ọ bụla e kewara mbadamba ụzọ n'ime ọkara) ma na-amụ ihe ga-ekwe omume ịhọpụta ya na otu dị iche iche nke ndị mmadụ.

Jiri na agadi

N'ime ndị agadi, steeti arụ ọrụ nke ọtụtụ sistemụ (akụrụ, ọnya obi) na-ata ahụhụ, yabụ, ọtụtụ ndị ọrịa na-eji ọgwụ eme ihe iji lekọta ha. Ma ọ bụrụ na ọgwụ ọgwụ adịghị, ka ịhapụ ịhapụ Langerin ma ọ bụ gbanwee usoro ọgwụgwọ ya (ọ bụrụ na ọ dị mkpa, mebie mbadamba ahụ n'ime ọkara, were otu).

Inye umuaka

Edinyere ọgwụ ọgwụ maka ụmụaka gafere afọ iri. N'oge nwata, a na-ahọrọ ọgwụ ndị ọzọ. Emebeghị ọgwụ ahụ n'oge ọ bụ nwata, yabụ enweghị data na nsonaazụ ya na uto, mmepe na ntorobịa nke ụmụaka, ọkachasị na iji ogologo oge. Ya mere, ekwesịrị iji ya kpachara anya na afọ nke 10-12.

Jiri n'oge ime na lactation

Mgbe ị na-eme atụmatụ ịtụrụ ime, ịkwesịrị ịkwụsị ị Lanụ Langerin ma kọwaara dọkịta gị ihe a. Ọ ga-edenye insulin kwesịrị ekwesị, ọ ga-adị mkpa iji ya mee ihe n’oge oge ọmụmụ a. Edepụtara mmetụta metformin na nwa ebu n’afọ dịka B.

Mgbe ị na-eme atụmatụ ịtụrụ ime, ịkwesịrị ịkwụsị ị Lanụ Langerin ma kọwaara dọkịta gị ihe a.

Emebeghị nnyocha n'oge ị na-enye nwa ara, ọ nweghị data na ntinye nke metabolites n'ime mmiri ara ehi, yabụ, n'oge ị na-enye nwa ara, ịkwesịrị ịhapụ ọgwụ.

Doụbiga ọgwụ ókè

Mgbe ị na-eji usoro ọnụọgụ dị elu karịa ka ọ dị mkpa, ihe ịrịba ama na-etolite: lactic acidosis, mmetụta nke akpọnwụ n'ọnụ, oghere mucous, anụ ahụ, akwara na obi mgbu, iku ume ngwa ngwa, nchekasị ụra, ihe mgbaàmà ọnya mmụọ, nsogbu akwara ozi, akwara afọ, mgbu, ọgbụgbọ, nsogbu nke obi, oliguria, ICE. Na mgbakwunye, ọnọdụ hypoglycemic adịghị etolite. Enweghị ọgwụgwọ ọ bụla akọwapụtara. Dika ogwu eji eme ihe, a na - aru ​​oru akwara di na onodi banyere ya n’ime ya, a na - emekwa ọgwụgwọ symptomatic. Ọ dị mkpa ịwepụ ọgwụ ngwa ngwa.

Ngwakọta ndị amachibidoro

Ọ bụrụ na ọ dị mkpa iji mepụta usoro nke a ga-eji mee ihe ndị nwere ayodiin, ị ga-akwụsị iwere Langerin n'ime ụbọchị abụọ. Na ịmaliteghachi ọgwụ ahụ ga - ekwe omume ụbọchị 2 mgbe ọmụmụ ihe ahụ gasịrị, tupu nke a, a ga - enyocha ule iji nyochaa ọnọdụ sistemụ gbasara akụrụngwa. Ma ọ bụghị ya, mmepe nke ọdịda akụrụ ga-ekwe omume, ihe ize ndụ nke lactic acidosis.

Gliformin nwere ike ịbụ analog nke ọgwụ.

Ejighị ọgwụ Danazol na ọgwụgwọ nke Langerin. Nke a bụ nke shuga dị elu, acidosis, na ihe ọghọm nke coma. Ya mere, a ga-enyocha glycemia.

Mgwakọta chọrọ ịkpachara anya

Na oke akpachapụ anya, ekwesịrị iji ọgwụ mee ihe yana sistemu na systemic ma ọ bụ mpaghara glucocorticosteroids, ACE inhibitors, diuretics, beta-2-sympathomimetics - otu ọgwụ ndị a nwere ike belata shuga ọbara. Ya mere, ị kwesịrị ịdọ onye ọrịa aka na ntị gbasara nke a, yana dozie usoro nke Langerin.

Chlorpromazine na antipsychotics bụkwa ọgwụ, yana mgbakwunye nke ekwesiri idozi metformin iji mee ihe.

Mmanya ndakọrịta

Ihe ọ alcoholụ alcoholụ na-aba n'anya na-ekwekọ. Mgbe ejikọtara ya na ethanol, ihe egwu nke ibute steeti lactic acidotic na-abawanye, ọkachasị nsogbu ya na imeju (mmebi imeju) ma ọ bụ na nri adịghị ezu.

Ihe ndị dị na Langerin bụ ọgwụ dị otú a:

• Glyformin
• Gliformin N'oge,
• Glucophage,
• Metformin
• Metfogamma,
• Mpempe akwụkwọ,
• Siofor na usoro onunu ogwu di iche iche (1000, 800, 500),
• Vero-Metformin,
• Glycomet 500.

Nyocha banyere Langerin

Anton, onye dị afọ 48, Oryol: “Anọwo m na-arịa ụdị ọrịa shuga 2 ruo afọ 3. Dọkịta tiri ọgwụ ahụ. Obi dị m ụtọ na enweghị ihe ọ bụla ọ na-akpata, na shuga adịghị elu. ”

Anna, onye dị afọ 31, Moscow: “Ana m arịa ọrịa shuga 2, arịara m ọrịa ihe fọrọ nke nta ka ọ bụrụ afọ ise. N'afọ mbụ ọ nọgidere nọgide na-enwe glucose site na mmega ahụ na nri. Agbanyeghị, enweghị ezigbo ọrụ ọ bụla. Dọkịta tiri ọgwụ a na ọgwụ nke ọgwụ 850 mg ugboro abụọ n'ụbọchị. Enweghị mmetụta ọ bụla. ”

Vasily, dị afọ 28, Krasnodar: “A chọpụtara ụdị ọrịa shuga 2 ụdị ihe karịrị otu afọ gara aga. Ana m a thisụ ọgwụ a. Dọkịta ahụ kwuru na ya na-arụ ọrụ nke ọma ma na-eme ka glucose dị mma. Ejiri 500 mg nke kacha nta. Of shouldụ ọgwụ ahụ kwesịrị ịdị mgbe niile, ọ nweghị mmetụta ọ bụla, yabụ echere m na ọgwụ dị mma. ”