CLINDACIN CANDLE

Clindacin, gụnyere dịka ihe eji arụ ọrụ ọgwụ mgbochi lincosamide – clindamycinbụ usọbọ mpaghara eji eji gynecology maka ọgwụgwọ nke igbonerellosis (vaginosis) nke ọrịa nje sitere. Ofzọ usoro nke ụdị ọgwụ ọgwụ mpaghara (ude, suppositories) bụ iji mee ka usoro protein protein intracellular dị na sel microbial pụta, nke na-eme na ọkwa nke nnukwu 50S ribosomal subunit.

Usoro ihe nkiri clindamycin sara mbara. Na usoro onunu ogwu, aruma nke ogwu nke ogwu site na otutu ụmụ nje. Na elu dos clindamycin e ji ihe ndị nje virus mebiri iji mebie ụfọdụ nje na-efe efe.

Isi ọrụ clindamycin hụrụ n'ihe metụtara ụmụ njena-eduga na nguzobe nje na-akpata njegụnyere: Mobiluncus spp. (mobilunkus) Gardnerella vaginalis (gardnerella vaginalis) Bacteroides spp. (bacteroids) Peptostreptococcus spp. (peptostreptococcus) Mycoplasma hominis (mycoplasma hominis).

Ọnwụ anaghị emetụta iku clindamycin bụ ụdọ Candida albicans (throo) na Trichomonas vaginalis (ọghọm trichomonas).

Intravaginal (n'ime ikpu) otu ogwu nke clindamycin na dose nke 100 mg na-eduga na mkpokọta sistem nke ihe dịka 4% nke ọgwụ (ihe dịka 4 mg). Plasma nke clindamycin nke dị plasma bụ 20 ng / ml.

Nsonaazụ

Patientsfọdụ ndị ọrịa nwere clindacin chere mmepe nke mmetụta ọjọọ na-adịghị mma, gụnyere: itching na ikpummuta maculopapular rashomume urticariammepe cervicitis ma obu colpita (vaginitis) Mgbakasị vulvovaginalmmetụta na-ere ọkụ.

Site na usoro hematopoietic obere, a chọpụtara ihe ndị a: thrombocytopeniaatụgharị leukopenia, eosinophilia, neutropenia, agranulocytosis.

N'ihe banyere nnabata clindamycin dị ukwuu, ngosipụta nke nsonaazụ nsonaazụ ya nwere ike, gụnyere ntinye nke pseudomembranous enterocolitis (dị ụkọ).

Clindacin ude, ntuziaka maka ojiji

A na-eme ude ude ka eji agwọ intravaginal site na iji ihe pụrụ iche, otu oge ga - etinye ya na kit ahụ maka ngwaahịa ọgwụ. Na-atụ aro ị dailyụ ude kwa ụbọchị nke ude bụ 100 mg clindamycin (olu nke onye choro ihe juputara nke oma). Ntinye ọgwụ a na-eme nke ọma na mgbede (tupu alakpu ụra). Oge ọgwụgwọ, dịka iwu, ga - ewe ụbọchị atọ ruo ụbọchị asaa.

Ojiji nke itinye akwụkwọ

Maka ntinye na ude nke ude ka ọ bụrụ nke ọma, a na-atụ aro ka ndị na-eji mkpofu diski mee ihe na ngwugwu ahụ ma gbasoo usoro ha ji eme ihe, ya bụ:

• wepu okpu nchebe na tube nke ude,
• gbanye ebe ndị na-eji rọba rọba
• afanyekwa na njedebe nke tube ahụ iji mejupụta onye na-abanye ya kpamkpam (a na-ewere onye na-abanye ya ka ọ jujuru afọ mgbe ọkpọ ya na-agagharị onwe ya na-akwụsị),
• dinara ala na azụ gị, tinye onye tinye ya n'ime ikpu dịka o kwere omume,
• jiri nwayọ tinye onye na-etinye ya na ọkpọ ahụ ruo mgbe ọ tọgbọ chakoo,
• wepu onye na-eji ya acho ya nke oma, tufuo ya.

Candles clindacin, ntuziaka maka ojiji

A na-ejikwa supintitories Clindacin mee intravaginally, yana otu nlekọta kwa ụbọchị nke suppository nke 1st, ọkacha mma na mgbede (tupu alakpu ụra). Oge ọgwụgwọ, dịka iwu, ga - ewe ụbọchị atọ ruo ụbọchị asaa.

Maka iji ọgwụ mee ihe n'ụzọ ziri ezi, a ga-ahapụrịrị ikike nchekwa site na nchịkọta dị n'èzí site na ịchacha ihe nkiri ahụ n'akụkụ contours kandụl. Mgbe ahụ, n’ọnọdụ nke supine, banye n’ime suppository n’ime ikpu oke dị ka o kwere mee.

Mmekorita

Mgbe ejikọtara ya na clindamycin, arụmọrụ nke aminoglycosides na-abawanye (Ptkpa ike), Rifampicin na Gentamicin.

Clindamycin ekwekọghị Aminophylline, Erythromycin, Sulfate magnesium, Ampicillin, Calcium gluconateusoro diphenylhydantoin na barbiturates.

Nsonaazụ nke clindamycin na-eme ka izu ike nke anụ ahụ rute n'ihi ikpughe n-anticholinergics.

Ofzọ nke ngwa

Ndị kandụl Clindacin itinye: intravaginally. Tupu ojiji, a na-ahapụpụ otu suppository site na nkwakọ ngwaahịa, mgbe ebipụchara ihe nkiri ahụ na ntule nke suppository, a ga-ewebata ya ma ọ bụrụ na ọ ga-ekwe omume, n'ime omimi, n'ọnọdụ supine.
1 suppository 1 oge kwa ụbọchị, ozugbo tupu ụra maka 3-7 ụbọchị n'usoro.

Mwepụta wepụtara ya na ọgwụ mejupụtara

Clindacin dị n'ụdị suppositories maka nchịkwa anụ na ngwugwu ọnya atọ nke igbe. Ntụziaka a nwere ntuziaka zuru ezu.

Ihe kachasị dị mkpa nke ọgwụ ahụ bụ clindamycin phosphate, mkpụrụ ndụ ọ bụla nwere 100 mg nke ihe a. Ngwakọta nke kandụl ahụ nwekwara ọtụtụ ihe inyeaka.

Ngwongwo ogwu

Clindacin bụ ọgwụ nje sitere na otu nke linksamides. Ihe na-arụ ọrụ nke ọgwụ ahụ na-egosipụta ọrụ ọgwụgwọ dị elu n'ihe metụtara ọtụtụ ụdị ọrịa ọrịa. Ihe nke ọgwụ ahụ bụ bacteriostatic, ya bụ, clindamycin phosphate, nke bụ akụkụ nke suppository, na-egbochi uto na ịmụpụta mkpụrụ ndụ nke akwara pathologies site na igbochi njikọ nke protein nke microbial cell.

Ọgwụ a na-arụpụta nke ọma megide staphylococci, streptococci, corynebacteria, mycoplasmas, peptococci, clostridia. Tupu ịkọwa ọgwụ suppositories, nwanyị ga-enwerịrị ọgwụ nje na nje nke inyocha ihe nzuzo iji wee mara banyere nje ahụ na ọgwụ nje.

A na-eji ọgwụ ahụ eme ihe na gynecological maka ọgwụgwọ nke nje na-akpata nje nke nje microorganisms nke nwere clindamycin.

Ihe ngbanwe

Tupu ịmalite ọgwụgwọ iji ọgwụ ahụ, onye ọrịa ahụ kwesịrị ịga leta ọkachamara n'ọrịa ụmụ nwanyị, mee nyocha ma jiri nlezianya gụọ ntuziaka agbakwunyere. A na - enyefe ndị ọrịa nwere ọgwụ mgbochi na clindamycin ma ọ bụ ihe inyeaka ndị mejupụtara ọgwụ ahụ, ụmụ nwanyị dị ime na ndị nwere ọrịa ọjọọ nke mgbidi nwanyị.

Jiri n'oge ime na lactation

N’ime oge izizi nke ịtụrụ ime, enyeghị ọgwụ atụ maka ọgwụgwọ maka ndị nne dị ime. Nke a bụ n'ihi ezughị ozi banyere nsonaazụ nchekwa nke clindamitacin na mmepe nwa ebu n’afọ, na mgbakwunye, n’ime izu iri na abụọ mbụ, etolitela akụkụ na sistemu nwa nke amụghị nwa, mmetụta nke ọgwụ nwere ike imetụta usoro a.

N’ime oge nke abụọ na nke atọ nke ịtụrụ ime, iji suppositories ga-ekwe omume naanị dabere na njiri nlezianya dị n’okpuru nlekọta nke otu ihe omume si dị na uru dịịrị nne na-atụ anya ga-adị elu karịa ihe ọghọm o kwere na nwa ebu n’afọ.

Nsonaazụ

N'izugbe, ndị ọrịa na-anabata ọgwụ ahụ nke ọma, ka ndị mmadụ nọ, na-enwewanye mmụọ nke mmetụta uche na clindamitacin, mmeghachi omume na-esote nwere ike ịmalite:

• Na akụkụ ahụ nke akụkụ ọmụmụ - mmepe nke usoro mkpali nke cervix, vaginitis, colpitis,
• Site na akwara hemopoietic - na -ebelata ọnụ ọgụgụ leukocytes, neutropenia, eosinophilia, thrombocytopenia, agranulocytosis,
• Mmeghachi omume mpaghara - ọkụ, itching na ikpu, ọnya na ahụ erughị ala,
• Sistem nke iji ọgwụ eme ihe dị ala, mana n'ọnọdụ ndị anaghị adịkarị, nwere ike ibute mmepe nke enterocolitis pseudomembranous.

Ntụziaka pụrụ iche

N'oge a na-eji ọgwụ ndị na-eme ka ọ bụrụ nwanyị, a na-atụ aro ka ya zere mmekọahụ.

Ebe ọ bụ na mgbe a na-eji ọgwụ ọgwụ dị na nwanyị eme ihe, enwere ike ịgbanarị mmerụ ahụ, a ga-eyi akwa nhicha ihe ọcha maka nkasi obi na ịdị ọcha.

N’oge nsọ, a naghị a treatmentụ ọgwụ. Should ga-eche ruo mgbe ngwụcha nke ụbọchị dị oke egwu ma naanị mgbe usoro ọgwụgwọ ahụ gasịrị.

N'oge ime na lactation

Dabere na ntuziaka gọọmentị, ọmụmụ banyere nyocha nke nchekwa nke clindacin mgbe tụụrụ ime n’oge ọnwa atọ mbụ Emeghi ya, n'ihe metụtara nke a, anaghị akwado ya iji oge a. Ọgwụgwọ Clindacin maka ụmụ nwanyị n’oge Oge nke II na III nke afọ ime kwere naanị n'ọnọdụ nke oke uru ọghọm dị n'ịgwọ ọrịa dị otú a maka nne, ma e jiri ya tụnyere nsonaazụ ọjọọ ọ nwere ike ibute nwa ebu n’afọ.

N'agbanyeghi nke a, na gynecology enwere omume ịhọpụta clindacin na Oge nke II na III nke afọ imeebe ọ bụ na ụfọdụ Ọrịa na-efe efemkpa ọgwụgwọ dị otú ahụ n'ezie. N'iburu n'uche nyocha banyere ọgwụ a n'ụdị ude, yana nyocha banyere suppositories n'oge afọ ime n'oge ndị a, ọ bara uru ịmara na n'ọtụtụ oge, ọgwụgwọ na Clindacin butere mkpochapụ ọrịa na-enweghị ihe ọ bụla na-adịghị mma maka nne na-atụ anya nwa na nwa ebu n’afọ.

Mwepu nke Intravaginally Jiri clindamycin Agụghị mmiri ara nke nne na-enye nwa ara, n’ihe banyere ya, ebum n’uche ya n’oge ahụ lactation ga - ekwe omume naanị iji ezigbo ntụle nke uru ọgwụgwọ dị otú a maka nne na-atụnyere ihe ọghọm ndị ọ bụla nwere ike ịmụrụ nwa ọhụrụ.

Nyocha banyere Klindatsin

Imirikiti ụmụ nwanyị na-eji ọgwụ a maka ọgwụgwọ nje na-akpata nje, M na-ahapụ nyocha dị mma banyere supernitories clindacin, gụnyere ndị ọrịa manyere ị thisụ ọgwụ a ịtụrụ ime na oge nke II na nke III. Nyocha banyere ude Klindacin adịghị ọtụtụ, mana ha dịkwa mma n'ihe gbasara arụmọrụ yana nchekwa nke ọgwụ a. Na-achịkọta echiche niile ndị ọrịa nwere gbasara ọgwụgwọ Klindacin nje na-akpata nje, ọ dị mma ịkwado ya maka iji ya dabere na njiri gosipụtara ya, kama ọ bụ naanị mgbe ịgachara ọkachamara.

Ọnụ ahịa Klindatsin ebe ị ga-azụ

Tụnyere ndị ogbo ya maka ọgwụ eji eme ihe (gụnyere mmanụ okike, ude, supiume, capsules, wdg), ọnụ ahịa clindacin dị n'ọkwa dị elu. Dịka ọmụmaatụ, ọnụahịa Klindatsina na kandụl Nke 3 bụ ihe dịka 650 rubles (karị, enwere ike ịzụta kandụl 6 na nkezi maka 1300 rubles). Ọnụahịa udele clindacin dịgasị iche n'etiti 350-400 rubles kwa tube nke 20 grams.

Mmeghachi omume ọjọọ

Usoro ịtụgharị uche: mgbu mgbu, candidiasis na-efe efe, enweghị nsogbu nwoke na nwanyị, mwepu nke nwanyi, dysuria, pyelonephritis, vaginitis / vaginal virus.

Anụ ahụ dum: fungal na-efe efe, mgbu afọ, isi ọwụwa, mgbu afọ, mpaghara, ahụ mgbu n'akụkụ, mgbu ahụ niile, mpaghara edere, candidiasis.

Ọna nri: ọgbụgbọ, vomiting, afọ ọsịsa.

Akpụkpọ ahụ na akpụkpọ anụ mucous: itching (ọ bụghị na ntụtụ), ihe ọkụ, ihe mgbu na saịtị ịgba ahụ, itching (na ntụtụ).

Jiri n’oge ime ma ọ bụ n’ịra

Iji intravaginal nke clindamycin phosphate suppositories dị n’ime ụmụ nwanyị dị ime n’oge nke abụọ nke ọnwa ime, yana iji usoro clindamycin n’ime oge nke abụọ na nke atọ edutaghị mmetụta ọ bụla.

N’ime ụmụ nwanyị n’oge ọkara nke afọ ime, ekwesịrị ị drugụ ọgwụ a naanị ma ọ bụrụ na enwere ihe atụghị mgbagha.

Amabeghị ma clindamycin dị na mmiri ara ara mgbe intravaginal nke clindamycin phosphate, yabụ n'oge a na-enye nwa ara, ọgwụ ahụ nwere ike ịdebe ya naanị mgbe uru a tụrụ anya ka nne ya ga-akarị ihe nwatakịrị nwere ike ibute ya.

Mụaka anaghị eji ọgwụ ahụ.

Njirimara ngwa

Iji ọgwụ ndị nwere oghere na clindamycin nwere ike ibute mmepe nke microorganisms na-enweghị nsogbu, gụnyere yist.

Ogwu na nke palenteral nke clindamycin nwere ike ime ka afọ ọsịsa, na n'ọnọdụ ụfọdụ - colitis. Ọ bụrụ na, mgbe ị na-eji ụdị ọgwụ clindamycin maka ọgwụ intravaginal, ọgbụgba siri ike ma ọ bụ ogologo oge tolitere, mgbe ahụ, a ga-akagbu ọgwụ a, a ga-ebu ụzọ nyocha usoro kwesịrị ekwesị ma mesịa ịkọwa ya ma ọ bụrụ na ọ dị mkpa.

A ga-adọ ndị ọrịa aka na ntị na oge ọgwụgwọ ọgwụ suppositories nke nwanyị nwere clindamycin, mmadụ ekwesịghị ịbanye na mmerụ nwanyị, ya ejikwala ụdị ngwaahịa ndị ọzọ ezubere maka nchịkwa intravaginal (dịka ọmụmaatụ, tampons, douches).

Ngwaahịa a nwere ihe ndị nwere ike belata ike nke latex ma ọ bụ ngwaahịa rọba, dịka eriri akpa nwa ma ọ bụ ọgwụ mgbochi nwanyị. Yabụ, iji ọgwụ ndị dị etu a mgbe a na-agwọ ọgwụ ọgwụ n'ụdị nkwanye ugwu.

Ihe fọrọ nke nta ka ọ bụrụ pasent 30 (6.5 - 70%) nke clindamycin na-abanye na sistemụ sistemụ site na iji ọgwụ ike nke nwanyi.