Tụnyere nke Ampicillin na Amoxicillin > Ọgwụgwọ na mgbochi

Benzipenicillin, nke bụ monobasic acid, bụ mmiri na-enweghị ike nke ọma na mmiri ma bụrụ nke a na-akwụghị chịm, yabụ, ejiri ya mee ihe dị mma! nnu nke sodium, potassium na esters. Ọ na - eme ihe na microorganisms nke dịkarịsịrị na sel.

Gram-positive cocci na coli na-enwe mmetụta sodium nnu nke benzylpenicillin, karịsịa pneumococci (ihe ruru 95% nke ụdị), hemolytic na pyogenic streptococci. Agbanyeghị, benzylpenicillin na-arụ ọrụ naanị 10% nke nsogbu staphylococcus aureus, na epidermal staphylococcus na-eguzogide ya. Enterococci na-eguzogide ọgwụ penicillin

Site na ntinye IM, a na-etinye ọgwụ ahụ ngwa ngwa ma wepụ ya ngwa ngwa. Mgbe etinyere ya afọ, n'oge na-adịghị anya, penicillinases nke akụkụ eriri afọ na-emebi ya. Enweghị ike ịdabere na gburugburu acidic, yabụ enwere ike iji ya mee ihe. Ogologo ọgwụgwọ nke ọgwụ mgbochi n’ọbara na-ewe awa 3-4.

Ọ bụ ọkwa nke benzylpenicillin n'ime ọbara na-ekpebisi ike site na steeti imeju na akụrụ. Site na arụ ọrụ na-arụ ọrụ ezumike | (dịka ọmụmaatụ, na ndị ọrịa na-arịa ọrịa) T1 / 2 ruru awa 4-10, na ndị na-arịa ọrịa imeju ọ nwere ike iru awa 16-30. Benzylpenicillin na-abanye nke ọma na akwara niile na ahụ mmadụ niile ewezuga ụbụrụ, anụ ahụ na-ahụ anya, ihe na-emetụta ahụ.

Ọnụego ntọhapụ nke ọgwụ ahụ dabere n'ụdị usoro onunu ogwu, usoro nchịkwa na njiri mara onye ọrịa ahụ. Iwepu ahu aru ngwa ngwa bu ihe di nkpa iji gbaa gi aru nke obara. Iji wepu ihe ndọghachi azụ a, a na-emepụta ọgwụ ndị siri ike ịgwakọta na iji nwayọọ nwayọọ, na-enye nsonaazụ ogologo oge.

The nkezi ọgwụgwọ otu ọgwụ maka parenteral ochichi nke benzylpenicillin bụ 1 nde nkeji, kwa ụbọchị - 6 nde nkeji. Enwere ike ịbawanye ya na nkeji iri abụọ ma ọ bụ karịa.

Ikwesiri izere ịgwakọta ọgwụ penicillin na acid, alkalis, alcohols, potassiumganganate, hydrogen peroxide.

Na ọnọdụ septikị siri ike, a na-eji penicillin mee iv na micro-jet ma ọ bụ ntapu mmiri distilled maka ntụtụ ma ọ bụ ngwọta sodium chloride isotonic. Adtinye ọgwụ ndị ọzọ na ọgwụgwọ ahụ anaghị anabata. Ewebata ya na akwara 1-2 ugboro kwa ụbọchị yana ntinye olu

Dabere ogo nrụgide nke usoro nje, oge ọgwụgwọ penisilini dị site ụbọchị ole na ole ruo ọnwa abụọ ma ọ bụ karịa. Ojiji benzylpenicillin ka egosiputara n’okwu niile nke amamịghe nke pathogen. Ọgwụ a na-abụ ọgwụ nje dị oke mma maka ọgwụgwọ nke ọrịa a na-ebute. Na endocarditis, nkwenye nke uche nke pathogen ka benzylpenicillin ka a na-ewere dị ka ihe iwu.

Contraindications: akụkọ ihe mere eme nke allergies na ọgwụ penisilini, ụkwara ume ọkụ.

Ntutu nnu nke Oxacillin

• Na-atụgharị uche na penicillins ọkara na-eme ihe. Dabere na ụdị ọgwụ antimicrobial, ọgwụ a yiri nke methicillin, a na-etinye ya nke ọma mgbe a na-ewere ya ọnụ, bioavailability ya na-eri nri, ya mere ọ ka mma ị oxụ oxacillin na afọ efu.

Ntinye uche ọgwụgwọ nke ọbara n’ọbara dịruru elekere 3 ka emesịrị 0,5 g n’ọnụ otu awa tupu nri ma ọ bụ awa 2-3 ka emesịrị ya.

Ngwọta maka nchịkwa parenteral na-arụ ọrụ ruo ụbọchị 9 ma ọ bụ karịa. Oxacillin na-abanye n’ime ahụ na akwara dị iche iche dị ka penisilini. Site na ntinye / m, ntinye nke oxacillin n'ime ọbara dị elu karịa mgbe a na-ewere ya ọnụ.

Itinye na / n'ime ma ọ bụ / m 2-3 g na karịa ugboro isii 4-6 n'ụbọchị.

Ampicillin nwere ụdị ọrụ dị iche iche, ọkachasị gram-odi microflora nwere mmetụta na ya. Site na staphylococcal penicillinase mebiri ọgwụ ahụ, mana ọ na-ejigide mmachi acid mgbe ejiri ọnụ mee ya. Site na nsonaazụ ya na ahịhịa gram-positive, ọ naghị arụ ọrụ karịa penisilini, mana karịrị methicillin na oxacillin, tetracycline na chloramphenicol. Ampicillin na-arụ ọrụ karịa tetracycline na chloramphenicol megide akwara hemophilic, protea, shigella, enterococci, yana Escherichia coli. A na-eme ka mmetụta antibacterial nke ampicillin dị elu mgbe ejiri ya na aminoglycosides na oxa-cillin. Bioavailability nke ampicillin mgbe a na -ewere ọnụ ya ọnụ site na 40 ruo 60% ma dabere n'ọnọdụ eriri afọ.

Dabere na kinetik nke ọgwụ (nchịkọta ya na mmamịrị na bile), yana ọrịa urogenital na ọrịa systemic, a ga-atụle ojiji nke ampicillin n'ime usoro nke na -eme ka ọnụọgụ dị ike na ọbara. Mgbe ị na-etolite usoro ọgwụgwọ, ọ dị mkpa iji ntụnyere nke ọgwụ nje n'ọbara na ogo MP / C maka pathogen ahọpụtara. Ampicillin enweghị mmetụta nephrotoxic.

Maka ọgwụgwọ nke ọrịa na-akpata site na-abụghị hemolytic streptococcus, pneumococcus, meningococcus na hemophilic bacillus, nwere mmetụta dị ukwuu na ampicillin, itinye uche ya na ọbara nwere ike ghara ịfe 1 μg / ml, nke bụ 2 g, nke na-erughị 4 g kwa ụbọchị.

A na-anabata ọgwụ kachasị elu nke ọgwụ ahụ, na-enweghị mmepe nke mmeghachi azụ na-egbu egbu n'ime ọnwa 1-1.5 na ọ dịkarịrị ogologo oge Ọgwụgwọ a ka edobere iche iche n'otu n'otu wee kpebie ya n'ụdị na ogo ahụ.

A na-eji ampicillin (na capsules ma ọ bụ mbadamba) agwa ọnụ na 0,5 g kwa awa 4-6. Thebọchị kwa ụbọchị bụ 2-4 g, s ikpe siri ike - ruo 10 g ma ọ bụ karịa. Site na ntinye okwu / m - 0,5 g mgbe awa 4-6 gachara, kwa ụbọchị bụ 1-Zg.

Mmanya na obere ihe ize ndụ nke ịdoụbiga mmanya ókè na-eme ka o kwe omume iji ampicillin na-enweghị mgbochi pụrụ iche na ọgwụgwọ nke ọrịa na ọnọdụ nke akụrụ. Agbanyeghị, a na-agbazi usoro ọgwụgwọ ahụ, na-ebelata oke nke ọgwụ ahụ ma ọ bụ nwekwuo oge n'etiti ndị na-achịkwa. Site na nitrogen residual nke 80 mg, a na-ebelata ọgwụ mgbochi ọgwụ ahụ na 2/3, yana karịa 80 mg% - ka 1/3 kwa ụbọchị.

Contraindications: ekweghị ibe nọrọ, hypersensitivity na penisilini, nrụrụ akụrụ dị ukwuu.

• Dabere na ụdị nje ihe dị na antibacterial, ampicillin dị nso na Amoxicillin, mana ọrụ ọ na-emegide nje ndị nwere mmetụta dị njọ bụ ugboro asaa karịa asaa. A na-etinye ọgwụ mgbochi ahụ nke ọma mgbe a na -ekwu ya okwu ọnụ ma na-ekesa ya nke ọma na akụkụ ahụ na anụ ahụ.

Otu ọgwụ amoxicillin bụ 0.25-0.5 g maka nchịkwa ọnụ kwa awa asatọ, maka ụmụaka, ọgwụ kwa ụbọchị bụ 20-40 mg / kg ugboro atọ.

Mgbe ị na-a equalụ doses, ịta amoxicillin n'ime ọbara ruru ihe dị okpukpu abụọ karịa nke ịchekwa ampicillin. Aclọ ọgwụ ọgwụ anaghị agbanwe agbanwe dabere na nri.

Tụnyere njiri mara nke ampicillin na amoxacillin

Njirimara

Amoxicillin

Ampicillin

Mpempe usoro onunu ogwu

Maka nchịkwa ọnụ

Maka nrịba ọnụ na nke nchịkwa

Nnukwu eriri afọ (%)

Mmetụta nke oriri

Ọ bụghị emetụta

Na-ebelata mmịcha

Ọkụ umeji

Nnukwu oke

Elu

Ntinye uche na Sputum

Elu ma ọ bụ na-adịgide

Ọkpụkpụ ma ọ bụ dị ala

Mmegide megide staiclococci na-egbochi penicillin

Nsonaazụ

Ọrịa afọ ọsịsa

Ọrịa afọ ọsịsa, ọnya

Ihe ngosi dị iche iche dị nso na carbenicillin, piperacillin na-arụ ọrụ megide Klebsiella, enterobacteria, Neisseria, hemophilic na Pseudomonas aeruginosa. Otutu ọnya Pseudomonas aeruginosa na nje ndị dị ya nso na-enwe mmetụta ọhụụ na piperacillin: ọrụ ya ji okpukpu asatọ karịa ọrụ carbenicillin. Agbanyeghị, uche banyere ya n'ụdị carbenicillin na-eguzogide Pseudomonas aeruginosa dị obere. Beta-lactamases nke Staphylococcus aureus mepụtara, yana ụdị TEM, OXA, na CAPB nke nje na-adịghị mma na-ebibi piperacillin. Ọ na-eguzogide ọgwụ nke cephalosporinases.

A na-ahazi Piperacillin na / n'ime ma ọ bụ / m. Site na / na ntinye nke bolus nke 2, 4, 6 g nke ọgwụ mgbe nkeji 30 gasịrị, ekpebisiri ike itinye uche kachasị na ọbara - 300, 4U na 775 μg / ml, otu ọ bụla, ọnọdụ - 42 μg / ml. Site na ntinye / m, a na-abanyekarị uche kachasị mgbe nkeji 30 gasịrị, mana 40 μg / ml.

Na ọdịda akụrụngwa, T1 / 2 piperacillin na-abawanye: na-agafeghị oke - 2, na nnukwu - 5-6 ugboro. N'ime ụmụ amụrụ ọhụrụ na ndị ọrịa agadi, T1 / 2 toro ogologo, mkpochapu ihe na-ebelata. Na protein protein, ọgwụ ahụ na - ejikọ aka na 16-20%. A na-ekesa ya nke ọma na akụkụ ahụ na anụ ahụ, gụnyere obi, na-agbakọ na bile n'ọtụtụ dị elu (ruo 3-4 μg / ml), na-abanye nke ọma site na mgbochi ụbụrụ ọbara na ndị ọrịa nwere meningitis.

Pipedị irè nke piperacillin na njikọta na ọgwụ nje ndị ọzọ na ndị ọrịa nwere ọnya na-efe efe na neutropenia yiri nke ahụ mgbe ị na-eji cefotaxime na amikacin ma ọ bụ moxolactam na amikacin. Na monotherapy na ọgwụgwọ nke nje na-efe efe nke sistemụ nje virus nke ukwuu, mmetụta nke piperacillin yiri ka ọ na nke ceftazidime.

Mmetụta ọghọm: thrombophlebitis (4%), hemorrhagic diathesis (17.2%), leukopenia (4%), eosinophilia (5-6%), hyper-fermentemia trensient (2.3%).

Njirimara Ampicillin

Ihe bụ isi ji arụ ọrụ bụ otu aha. Na mgbakwunye, ihe inyeaka ndị ọzọ dị na nhazi ahụ. Ndị na-emepụta bụ ụlọ ọrụ Russia (dịka ọmụmaatụ, Synthesis).

Ampicillin na Amoxicillin nwere ụdị ọrụ dị iche iche ma na-alụ ọgụ n'ọtụtụ ụdị microorganisms pathogenic.

E mepụtala ụfọdụ usoro ịhapụ:

Ọgwụ 1 mpempe nwere 0.25 g nke ihe eji arụ ọrụ.
Capsules Na mpempe 1, 0.25 g nke ihe na-arụ ọrụ na-arụ ọrụ dị.
Nkwụsị 5 ml nwere 0.25 g nke onyinye na-arụ ọrụ.

Ampicillin bụ otu n'ime ihe ndị kasị dị irè na-egbochi ọgwụ nje. Ọ na-egbochi usoro nke imepụta mgbidi nke akụkụ sel n’ime nje. Ọgwụ a na-emegide microorganisms nke so na cocci. Nke a metụtara staphylococci, streptococci, gonococci, meningococci, pneumococci.

Ọgwụ na-egbochi ọtụtụ nje ndị na-adịghị mma gram. Dịka ọmụmaatụ, E. coli, enterobacteria, salmonella, wdg. Ma ọgwụgwọ ya anaghị arụ ọrụ megide ụdị mkpụrụ osisi penisillin, ebe ọ bụ na omume ha na-emebi ampicillin.

Oke mmanu nke nọ n’ọrụ n’ime ọbara ka a ga-enweta n’ime elekere ole ma ole ị ofụsịrị ọgwụ. Ọkara ọkara bụ ihe dịka awa 2. Ihe ahụ na-ahapụ ahụ ya na ihe ọleụ andụ na mmamịrị. A na-ewere ọgwụ a dị ka obere nsí. O dighi achikota n’ime aru mmadu. N'ihi nke a, a na-ahapụ ya ka ewere ya n'ọtụtụ buru ibu ogologo oge.

Ampicillin na-egbochi ọtụtụ nje ndị na-adịghị mma gram.

Edere ọgwụ ahụ maka ọgwụgwọ nke ọrịa ndị na-emetụta ampicillin. Ihe ngosi maka iji ya bu ndi a:

ọrịa nke ọrịa mkpali nke mpaghara ala nke akụkụ okuku ume, yana ọrịa nke imi, ọnụ, pharynx, ntị (ọ metụtara na oyi baa, akwara, tonsillitis, pharyngitis, sinusitis, otitis media, tonsillitis, colds),
usoro urological na usoro mkpali (nke a gụnyere urethritis, cystitis, pyelonephritis, prostatitis, gonorrhea, wdg),
ọrịa gynecological kpatara ọrịa,
usoro mbufụt na-efe efe na bile dule (na-emetụta cholangitis na cholecystitis),
ọrịa na-efe efe na eriri afọ (ọrịa ndị a gụnyere eriri afọ, ọnyụnyụ ọbara, enterocolitis, salmonellosis, typhoid, wdg),
Ọbara nke anụ ahụ na anụ ahụ dị nro nke ọrịa na-efe efe,
endocarditis
rheumatism
erysipelas,
ahụ na-acha uhie uhie,
meningitis
peritonitis
sepsis.

Contraindications na nsonaazụ ya

Ndị mmadụ n'otu n'otu ekweghị n'akụkụ ọgwụ ndị dị n'ọrụ ọgwụ ahụ. Ndị na-emepụta rụpụtara ihe doro anya na eji Amoxicillin, maka ndị mmadụ na-arịa ajọ ọrịa na-efe efe nke imeju na akụrụ. A naghị akwado ya maka iji ya na oke okpomọkụ, akpata oyi, yana mmụba nke oghere lymph.

Iji ya n’oge ime bụ naanị n’okpuru nlekọta nke otu dibia bekee.

Mmeghachi omume ọjọọ gụnyere nfụkasị, nchapu nke anụ ahụ, ọnya, itching, ede ede Quincke. Ngwá ọrụ ahụ nwere ike ibute mbufụt nke akpụkpọ ahụ mucous nke nasopharynx (rhinitis), profuse lacrimation (conjunctivitis), na-akpalite mgbu mgbu, n'ọnọdụ ndị na-adịghị ahụkebe, na-akpata ujo anaphylactic.

Kedu ihe dị n'etiti ampicillin na amoxicillin?

Ọgwụ abụọ a bụ ndị isi azụmaahịa na-enweghị mgbagha na ubi ha. Ha egosiputala onwe ha dika uzo di nma iji luso oria di iche-iche na oria anya.

Ha nọ n'otu otu ọgwụ nje nwere ọtụtụ ụdị na-emetụta ya, bụ pinicillins sarin-sịntetik. Ngwa ahịa abụọ a nwere njirimara ha maka ojiji, dị mfe, enweghị ọnụ ma dịkwa mfe.

Kedu ihe dị iche?

Ihe di iche n'etiti Ampicillin na Amoxicillin bu akụkọ banyere ọgwụ. Nke bụ eziokwu bụ na achọpụtara Ampicillin ogologo oge, ọtụtụ microorganisms nwere ike imeghari ma zụlite ihe mgbochi na ọgwụ nje a. Ya mere, ndị dọkịta na-eji Ampicillin belata.

Ihe ozo putara ihe bu ihe ndi ozo putara ihe ndi Amoxicillin nwere. Dabere na ìgwè hydroxyl, ọgwụ na-abanye n'ọbara ngwa ngwa, nke na-enye gị ohere ịmepụta itinye uche dị elu nke ihe na-arụ ọrụ n'ime ọbara, na-enye nsonaazụ.

Dabere na njirimara ndị a dị n'elu, ọ dị mma ịsị na ojiji nke Amoxicillin ga-aba uru karịa. Nke a bụ ọgwụ dị elu karị, nnabata nke a na-anabata ọbụna ụmụaka na-erubeghị afọ abụọ. Amoxicillin enweghi ọgwụ mgbochi akpọrọ, anụ ahụ na-anabata ya nke ọma ma enwere ike iji ya na ụdị mbadamba ma dịka ntụtụ. Na mgbakwunye, ịhapụ Amoxicillin ka a na-anabata n'oge ime na n'oge a na-enye nwa ara.

Ọ bụrụ na usoro ọgwụgwọ ahụ dị ogologo, mgbe ahụ ọ kachasị mma ịnye mmasị na Amoxicillin. Site na iji Ampicillin ruo ogologo oge, mmepe nke superinfection ga-ekwe omume. Ihe omume a na - eme na ọnọdụ ebe microorganisms anaghị azaghachi omume nke ọgwụ ahụ, ma n'okpuru nduzi nke gburugburu ebe obibi na - eme ihe ike, ha na - amalite ịmepụta mgbochi nchebe ma mụbaa na oke ọsọ, si otú ahụ na-ebelata ahụ nke na-eguzogide ọrịa mbụ.

Ntụziaka maka iji Ampicillin na usoro onunu ogwu

Tupu ịmalite usoro ọgwụgwọ, a ga-eme ule kwesịrị ekwesị iji chọpụta ụmụ nje ndị kpatara ọrịa ahụ na iji chọpụta mmetụta nke ampicillin.

A na-etinye usoro ahụ iche iche, na-eburu n'uche ọrịa ahụ, ọnọdụ nke ọrịa ahụ na ọnụnọ nke pathogen.

E kwesịrị iji okwu dị mbadamba ma ọ bụ nkwusiobi were mmịnụ, were mmiri hichaa ya, n'agbanyeghị nri.

Otu mkpụrụ maka ndị okenye mgbe ejiri ọnụ kwuo ya bụ 250-500 mg. Dosebọchị kwa ụbọchị bụ 1-3 g Nke kacha nha bụ 4 g kwa ụbọchị.

Dosebọchị maka ụmụaka bụ 50-100 mg kwa 1 n'arọ nke ịdị ahịrị. N’iburu ibu nke na-erughị 20 n'arọ, a na-atụ ọgwụ 12.5-25 mg kwa 1 n'arọ. A na-ekewa ụbọchị kwa ụbọchị ụzọ 4.

Oge ihe ọmụmụ ahụ dabere n'ịdị ogo ọrịa ahụ na arụmọrụ nke ọgwụgwọ.

Nkwadebe nke nkwusioru - gbakwunye mmiri na karama dị na karama ahụ ruo mgbe ihe ize ndụ ndị ahụ ma maa jijiji nke ọma. Nkwado nke akwadoro bụ nke kwụsiri ike n ’ọnọdụ ụlọ maka ụbọchị 14. Tupu ojiji nke ọ bụla, a ga-eme ka nkwụchi ahụ maa jijiji. 5 ml nke nkwusioru a kwadebere (1 scoop) nwere 250 mg nke ampicillin.

umu amụrụ ọhụrụ n’ime ọnwa 1 - 150 mg / n'arọ ibu arọ /,,
ruo otu afọ - dabere na ịdị arọ anụ ahụ 100 mg / kg kwa ụbọchị.,
site na afọ 1 ruo 4 - 100-150 mg / n'arọ nke ịdị arọ ahụ kwa ụbọchị.,
mụaka karịrị afọ anọ ka a na-enye ọgwụ 1-2 g kwa ụbọchị.

A na-ekewa usoro ubọchị kwa ụbọchị ka ọ bụrụ usoro 4-6.

Ogologo oge ọgwụgwọ na-adabere n'ịdị ogo ọrịa ahụ (site na ụbọchị 5-10 ruo izu 2-3, yana na usoro na-adịghị ala ala - ọtụtụ ọnwa).

Na parenteral intramuscular na nkwanye ugwu ma ọ bụ ntapu mmiri, otu ọgwụ maka ndị okenye bụ 250-500 mg. Dosebọchị ọ bụla kwa ụbọchị bụ 1-3 g Ọ bụrụ na ọnya na-arịa ọrịa siri ike, ọnụọgụ ahụ na-abawanye 10 g ma ọ bụ karịa.

Maka ụmụ amụrụ ọhụrụ karịrị ọnwa 1, otu ọgwụ kwa ụbọchị nke 100 mg kwa 1 n'arọ nke ịdị ahụ ya. Ofmụaka ndị dị afọ ole ọzọ ka etinyere 50 mg kwa 1 n'arọ. N'ọnọdụ ọrịa siri ike, ọnụọgụ ahụ na-abawanye. A na-ekewa kwa ụbọchị na ọgwụ mgbochi 4-6 kwa oge ọ bụla na awa 4-6. Ogologo oge ọgwụgwọ na injections intramuscular bụ ụbọchị 7-14, yana ọgbụgba - 5-7 ụbọchị. Dabere na akaebe nke onye ọrịa nwere ike ibuga ya na ntụtụ intramuscular.

Iji kwadebe ihe mgbochi maka irighiri akwara intramuscular, ihe ndị dị na vial ahụ na-agbari na mmiri milimita abụọ n'ime mmiri.

Iji kwadebe ihe ngwọta maka nchịkwa intravenal, a na-agbari otu ọgwụ nke ọgwụ (ọ bụghị karịa 2 g) na 5-10 ml nke mmiri maka ntụtụ ma ọ bụ ngwọta sodium chloride isotonic.

A na - eme nwayọ nwayọ nwayọ maka nkeji 3-5 (1-2 g maka nkeji 10-15). Ọ bụrụ na otu mkpụrụ karịrị 2 g, a na-a drugụ ọgwụ ahụ intravenously.

Nsonaazụ

Enwere ike ijikọ Ampicillin na nsonaazụ ndị a:

Ngosiputa ihe anwansị nke ụdị: itching, rhinitis, conjunctivitis, urticaria, exfoliative dermatitis, erythema multiforme exudative. Ọ na-esiri ike n'ụdị edem ede nke Quincke na ujo anafilactic,
Mmeghachi omume afọ: akpọnwụ akpịrị, ọgbụgbọ, ọgbụgbọ, ihe mgbu nke afọ, afọ ọsịsa, nsia dysbiosis, gastritis, stomatitis, mgbanwe uto,
Ihe ngosiputa sitere na sisitemu hepatobiliary na imeju: cholestatic jaundice,
Site na usoro ụjọ ahụ nke etiti: isi ọwụwa, neuropathy, ụjọ, nkwarụ (mgbe eji ya na elu doses).

Mmeghachi omume mpaghara nwere ike ịnweta site na iji ọgwụ intramuscular n'ụdị infiltrates, ihe mgbu na ntinye ahụ.

Ampicillin na contraindicated na ndị a:

nwekwuru uche na penisilini, cephalosporin, carbapenem,
na-arịa ọrịa kansa ọbara lymphocytic, mononucleosis na-efe efe.

Site na imeju imeju, a na-eji ọgwụ ahụ eme ihe mgbe niile na-eleba anya n'ihe ọ na-eme na plasma ọbara. N'ọnọdụ mberede, a na-eji ya maka ụkwara ume ọkụ, ụkwara ahịhịa na ọrịa ndị ọzọ na-akpata nfụkasị.

Iji nlezianya kpachara anya, a ga-ewere Ampicillin na ọdịda akụrụ, ịtụrụ ime, ụmụaka na-erubeghị ọnwa 1.

Symptomsụbiga ihe nrịba ama anya - ngosipụta nke ihe ọjọọ na-egbu ya na sistemụ akwara dị n’etiti (ọkachasị ndị ọrịa nwere akụrụ gbasara akwara), ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, ahaghị n ’mmiri elektrolyte (n’ihi ọgbụgbọ na afọ ọsịsa).

Ọgwụgwọ - lavage gastric, unyi na-arụ ọrụ, laxatives nke nnu, ọgwụ iji mee ka mmiri-electrolyte nwee nguzozi na Symptomatic. Ọ bụ hemodialysis wepụrụ ya.

Ampicillin analogs, ọnụahịa dị na ahịa ọgwụ

Ọ bụrụ na ọ dị mkpa, ịnwere ike iji dochie anya Ampicillin site na iji ọgwụ eme ihe - ọgwụ ndị a bụ ọgwụ:

Mgbe ị na-ahọrọ analogues, ọ dị mkpa ịghọta na ntuziaka maka ojiji nke Ampicillin, ọnụahịa na nyocha nke ọgwụ nwere mmetụta ndị yiri ya anaghị emetụta. Ọ dị mkpa ịnweta ndụmọdụ nke dọkịta na ịghara ime mgbanwe ọgwụ ọ bụla.

Ọnụ ego nke mbadamba ọgwụ na ụlọ ahịa ọgwụ na Moscow site na 19 rubles.

Ndụ shelf bụ afọ 3. Chekwaa na nkụ, gbara ọchịchịrị na 15 Celsius C ruo 25 Celsius.

Ampicillin bụ ọgwụ mgbochi ọgwụ nke na - eme ka mmiri ghara ịba uru ma nwee ọgwụ mgbochi ma ejiri ya na-agwọ ọtụtụ ọrịa nje sitere na nje.

Mwepụta wepụtara ya na ihe mebere

Ampicillin ọgwụ ahụ dị n'ụdị mbadamba, capsules na ntụ ntụ maka nkwadebe nke ndị na-enyo enyo. A na-emepụta mbadamba na capsules na 0.25 g nke ọ bụla. Otu ngwugwu nwere 10 mbadamba ụrọ 10 ma ọ bụ 20 nke acha ọcha nwere ọdịdị cylindrical. Ọgwụ n'ụdị ntụ ntụ nwere agba ọcha na agba aja aja. Ọ na-atọ ụtọ ma nwee ezigbo isi. A na-enweta ntụ ntụ n'ime ite iko oroma 60 ml.

Na usoro onodu ogwu nile nke Ampicillin, ihe eji arụ ọrụ bụ ọgwụ ampicillin trihydrate. Otu mbadamba ihe nwere 0.25 g nke ihe eji arụ ọrụ, yana ndị nwere ụdị n'ụkpụrụ steepụ, talc, stearate calcium na magnesium stearate.

5 ml nke nkwusioru a kwadebere site na iji ntụ ntụ Ampicillin nwere 125 mg nke ampicillin trihydrate na ndị na-eso ya:

Silicon dioxide colloidal,
Sodium carboxymethyl cellulose,
Sodium citrate na-egbu egbu,
Ponceau 4R (E124),
Sodium benzoate (E211),
Sucrose
Udara ọma.

Ihe ngosi maka iji Ampicillin

Dabere na ntuziaka maka Ampicillin, e mere ọgwụ a maka ọgwụgwọ nke ọrịa nje dị iche iche nke microflora nwere mmetụta. Otu n'ime ha bụ ọrịa ndị na-efe efe na-efe efe nke akụkụ okuku ume:

Dabere na ntuziaka maka Ampicillin, ọgwụ dị irè na ọrịa na-efe efe na-adịghị ala ala nke digestive, genitourinary na eriri afọ, gụnyere cystitis, cholecystitis, pyelitis, salmonellosis na ndị ọzọ.

Dika ntuziaka maka Ampicillin, eji ọgwụ a eme ihe maka ịgwọ ọrịa ndị a:

Nkpata nti, imi na akpịrị
Meningitis
Ahụ ọkụ na-acha odo odo,
Endocarditis
Akpịrị na anụ ahụ dị nro,
Septicemia
Rheumatism
Odontogenic na-efe efe
Sepsis
Erysipelas
Ọkpụkpụ

Usoro onunu ogwu na nchịkwa nke Ampicillin

Ampicillin n'ụdị niile kwesịrị iwere ọkara elekere ma ọ bụ otu awa tupu nri. Usoro ogwu a ka edobere n’otu n’otu n’ile nye onye oria obula, dabere ogo ya na udiri oria a, tinyere iburu n’onodu ebe oria ya na oria onye ori.

Otu ụdị ọgwụ a n'ụdị mbadamba maka ndị okenye bụ 250-500 mg. Thebọchị ọ bụla bụ 1-3 g. Maka ụmụaka na-erughị 20 n'arọ, kwa ụbọchị Ampicillin bụ 12.5-25 mg / n'arọ, maka ụmụaka na-adị ihe karịrị kilogram 20 ọ bụ 50-100 mg / kg. Dịka iwu, a na-ekewa usoro ọgwụ kwa ụbọchị ụzọ 4.

Iji kwadebe nkwusioru ahụ, a na-awụpụ mmiri dị milimita 62 n'ime mmiri vidiyo na ọgwụ ahụ ma maa jijiji nke ọma. Maka ndị ọrịa okenye, ọgwụ Ampicillin dị n'ụdị ntụ ntụ bụ 500 mg kwa awa isii.

N'ọnọdụ ụfọdụ, gụnyere oyi baa, akwara, na ọrịa dịgasị iche iche nke akwara mkpụrụ ndụ na eriri afọ, a na-eji usoro onunu ogwu nke 500 mg ugboro anọ kwa ụbọchị. Site na gonorrhea, 2 g nke ọgwụ a na-ewerekarị oge 1 kwa ụbọchị.

N'ime ụfọdụ ọrịa na-efe efe, ọ nwere ike ịdị mkpa ka iwelie ọgwụ Ampicillin n'ụdị mgbochi. Ọ bụrụ na ha dabara n'ụdị siri ike, ọgwụ ọgwụ maka ndị okenye nwere ike ịbụ 3 g kwa ụbọchị.

Dosebọchị ọgwụ Ampicillin ntụ ntụ kwa ụbọchị maka ụmụaka na-erubeghị afọ atọ bụ 100-200 mg / n'arọ ahụ. E kee ya ụzọ anọ. Maka umuaka kariri afo ato, usoro onunu ogwu ahu di otu a: 50-100 mg / n'arọ aru, kewara ya ugboro anọ.

Nsonaazụ nke Ampicillin

Ojiji nke Ampicillin n'ụzọ ụfọdụ nwere ike ịkpasu mmetụta ndị ọzọ n'ụdị mmeghachi omume nfụkasị ahụ. Themfọdụ n’ime ha bụ ndị a:

Imeji Quincke,
Akpụkpọ ahụ na itching,
Ọrịa
Erythema multiforme,
Rhinitis
Exemoliative dermatitis,
Urticaria.

N'ọnọdụ ndị na-adịghị ahụkebe, ampicillin nwere ike ibute mgbu nkwonkwo, ujo anaphylactic, eosinophilia, na ahụ ọkụ. Oge ụfọdụ ọgwụ a na-ebute nsonaazụ site na sistem nri dịka ọgbụgbọ, ọgbụgbọ, ịba ụba gas na eriri afọ na afọ ọsịsa.

Ojiji nke ampicillin nwekwara ike kpasu iwe:

Stomatitis
Ọbara
Agranulocytosis,
Leukopenia
Asedba ụba nke ọrụ hepatic transaminases,
Thrombocytopenia
Paiudomembranous colitis,
Nnukwu oria.

Ogologo oge ịgwọ ọrịa na Ampicillin nwere ike ibute nnabata karịa ndị ọrịa adịghị ike. N'ụdị ndị a, ọ dị mkpa ịmalite ị toụ vitamin.

Usoro na ọnọdụ nchekwa

Ekwesịrị ịchekwa Ampicillin n'ebe gbara ọchịchịrị na ebe ọkpọkọ na-erughi ụmụaka, na okpomọkụ ụlọ. Ndụ nchekwa nke capsules na ntụ ntụ bụ afọ 3, yana maka mbadamba - afọ 2.

Ndị na-emepụta ọgwụ ugbu a na-enye ọtụtụ nhọrọ nke ọgwụ nje. Offọdụ n’ime ha nwere ọrụ dịgasị iche, ndị ọzọ na-alụ ọgụ naanị maka ụfọdụ ụmụ irighiri ihe. A machibidoro ị Suchụ ọgwụ ndị dị otú a iji aka ha, n'ihi na nsonaazụ ọgwụgwọ nwere ike ịdị iche iche. Isiokwu taa ga-agwa gị gbasara Ampicillin. Ntuziaka maka ojiji, nyocha, analogues na usoro eji eme ihe ziri ezi ka aga-elebara gị anya.

Mee ndoputa ozugbo ihe omuma a natara ekwenyeghi ime ka ị jiri aka gi nye onwe gi ogwu. Ọ bụrụ na ị nwere nsogbu ahụike yana ọgwụ dị oke mkpa dịka ọgwụ nje, ị ga-achọrịrị enyemaka ahụike. Naanị na nke a enwere ohere maka mgbake ngwa ngwa.

Nkọwa nke Ampicillin

Ngwakọta kachasị arụ ọrụ bụ ampicillin. Nke a bụ ọgwụ mgbochi oke, nke dị n'ụdị mbadamba, capsules, mgbochi.

Ngwá ọrụ ahụ na-egbochi iweze mgbidi nke nje. Ọzọkwa, Ampicillin dị irè naanị megide microorganisms sitere na cocci: staphylococci, gonococci, pneumococci. Ọzọkwa, ọgwụ a na-enyere Escherichia coli, Salmonella, ọgụ na nje ndị ọzọ na-adịghị mma gram.

Ma n'otu oge ahụ, ọ baghị uru na ụdị ọgwụ nje penicillin na-emepụta, na-ebibie ya n'okpuru ọrụ ha.

N’ime awa 2-3 mgbe nchịkwa gachara, akarị akarịrị akụrụngwa na-arụ ọrụ n’ime ahụ. Oge ikpochapu ihe dika awa abuo - a sachapu ogwu ahu na mmamiri.

A na-ele ọgwụ a anya dị ka mmiri nwere nsí dị ala n'ihi na ọ naghị ekpokpo ahụ. Ya mere, a na-ahapụ ya ka ọ were ya n'ọtụtụ buru ibu ruo ọtụtụ izu n'enweghị nsogbu ahụike, dịka ihe gosiri.

Ihe ngosi maka ojiji:

ọnya afọ ọria, otiti, sinusitis, otitis media,
urethritis, pyelonephritis, gonorrhea,
cholecystitis
eriri afọ, salmonellosis,
rheumatism, ịcha uhie uhie, sepsis.

Ọ bụ dọkịta nwere ike ịkọwa ọgwụ ahụ maka ọgwụ ahụ, usoro ọgwụgwọ ahụ, na-eburu afọ onye ọrịa yana akụkọ banyere ahụike. Ọ gaghị ekwe omume ịpụ na usoro ọgwụgwọ ndị dọkịta gwara ka ha wee ghara ime ka ọrịa ahụ ka njọ.

Nkọwa nke Amoxicillin

Amoxicillin bụ ọgwụ buru ibu nke na-enye ọgwụ maka ọgwụgwọ nke ọrịa ndị nje mmerụ na-akpata ya.

A na-eji Amoxicillin mee ihe maka ọla kọpa, oyi baa, na ọrịa na-efe efe.

Isi ihe ngosi maka ojiji:

ngwo, ponia,
ọrịa na-efe efe na-efe efe
cystitis, pyelonephritis,
ọrịa nje na-efe efe.

N'ọnọdụ ụfọdụ, a na-enye ọgwụ ọgwụ Amoxicillin dị ka onye prophylactic n'oge usoro nlekọta ahụike dị iche iche na mkpo onu, mkpochapụ Helicobacter Pylori. Iji mee ka ọgwụ dịkwuo nfe, enwere ike ịdebe ọgwụ clavulanic n'otu oge ahụ na ị takingụ ọgwụ.

E nwere ya n'ụdị dị iche iche: mbadamba nkume, capsules, suspensions, solution for አስተዳደር intravenous.

Mmetụta ọgwụ ahụ metụtara naanị nje bacteria - Amoxicillin anaghị emetụta ero ahụ, nje. Ejila ọgwụ nje a maka oyi, nke a nwere ike ibute mmepe nke nguzogide nje.

Kedu ihe dị iche

Ihe mbu di iche bu ihe di nkpa. Yabụ, na nchịkọta nke Ampicillin enwere sodium ampicillin, na ntụnyere ya - amoxicillin trihydrate. Ọgwụ dịgasị iche na mmeghachi omume ọjọọ. Maka ampicillin, ọgbụgbọ, afọ ọsịsa, dysbiosis, na mmepe nke candidiasis bụ akparamagwa.

Amoxicillin nwekwara ike ịnwe mmeghachi omume dyspeptik, mmepe nke superinfection, nke a na-akpata site na mmụba n'ọnụ ọgụgụ nke microorganisms ndị ọzọ.

Kedu ihe ka mma Ampicillin na Amoxicillin

Kpamkpam kwuo na ọ ka mma - ị gaghị enwe ike. Naanị dọkịta nwere ike inye ọgwụ mgbochi, dabere na mkpesa onye ọrịa nwere, nsonaazụ nke ule ya. Mana ọtụtụ mgbe na ọgwụgwọ nke nje na-efe efe nke na-apụta n'ụdị siri ike, a na-atụ aro ị takeụ Amoxicillin, agbakwunyere na clavulanic acid iji mee ka mmetụta ahụ ka mma.

Ejiri Ampicillin mee ihe n'ụzọ kachasị mma n'ịgwọ ọrịa ndị na-efe efe dị nro.

N’ime afọ ime na n’ọkpụrụkpụ nwa, ị ga-a takeụ ọgwụ ahụ naanị mgbe ịgachara dọkịta, ọ bụrụ na uru nne dị na ya karịrị ihe mmerụ ahụ ọ nwere ike ibute nwa ebu n’afọ. Enwere ike inye ụmụaka site na nwata, Amoxicillin, nyere ya ibu na afọ onye ọrịa.

Enwere m ike ị drinkụ Amoxicillin kama Ampicillin?

Dabere na Njirimara ọgwụ, 2 n'ime ndị ọrụ a nwere mmetụta yiri ya. Maka nke a, ọtụtụ ndị ọkachamara na-atụ aro maka Ampicillin ma ọ bụ Amoxicillin. Agbanyeghị, ọ gaghị ekwe omume ịhọrọ ọgwụ ma jiri aka gị rụọ ọgwụgwọ - naanị dọkịta nwere ike ime nke a.

Agbanyeghị, ọ bụrụ na ọgwụgwọ chọrọ mbadamba mbadamba ogologo oge, edepụtara Ampicillin n'ihi obere bioactivity ya. Ọ bụrụ na ị na-ewere Amoxicillin mgbe niile, nke a nwere ike ibute nsonaazụ ndị ọzọ.

Ọ bụrụ n ’iji ọgwụ nke abụọ dochie Amoxicillin, mgbe ahụ ọ bụ nsonaazụ belata obere ọgwụ, itinye uche ọgwụ na ọbara agaghị ezu. N'okwu a, ọrịa ahụ nwere ike banye n'ọgbọ na-adịghị ala ala, mgbe ahụ a ga-achọ ọgwụgwọ na ọnọdụ ụlọ ọgwụ.

Echiche nke ndị dọkịta na nyocha ndị ọrịa

Olga, 42 afọ, onye na-agwọ ọrịa

Maka ọgwụgwọ nke ọrịa ENT na ọrịa eriri afọ, A na-enye ndị ọrịa ọgwụ Amoxicillin. Ngwá ọrụ a na-adịghị ọnụ, ọ na-alụ ọgụ nke ọma n'ọtụtụ ọrịa, nwere bioavailability dị elu, nke na-eduga na mbelata oge ọgwụgwọ na mmụba na arụ ọrụ ọgwụ. N'ọtụtụ oge, enweghị mmeghachi omume ojoo.

Irina, 35 afọ, Moscow

N'ihi nnukwu hypothermia, ọ butere oyi ịba, ọrịa ahụ nwetakwara usoro na-adịghị ala ala. Dọkịta ahụ tiri Amoxicillin dị ka akụkụ nke ọgwụgwọ siri ike. Ka ụbọchị asaa gachara, o bidoro nwewe ọkụ, ụkwara na ahụ ọkụ agaghị apụ n'anya. Mgbe ọgwụgwọ ahụ gasịrị, dọkịta ahụ gwara ị takingụ ọgwụ mgbochi immunomodulating.

Elena, 24 afọ, Perm

Ebiri m mkpụrụ osisi na-asa nke ọma, n'ihi nsị n'ihi nsia na nsia. Ejiri ya na Ampicillin 5 ụbọchị. N’oge a, enwere ike iwepụ ihe mgbaàmà ahụ. Ejiri m ọgwụ nje nke ọma, enweghị mmetụta ọ bụla.

Acquainmara mbu: ụdị ntọhapụ, ọnụ ahịa na ihe mejupụtara

Ihe na - arụ ọrụ nke ọgwụ ahụ bụ ọgwụ a na - akpọ ampicillin trihydrate. Analogs nke ọgwụ nje a nwere ike inwe otu ihe mebere ma ọ bụ dịrị iche na mmiri. Learn ga-amata banyere ha ma emechaa n’isiokwu ahụ. Ampicillin bụkarị nke dị n'ụdị mbadamba na ntụ ntụ. Nke ikpeazụ ezubere maka intramuscular ma ọ bụ nchịkwa intravenous. A ga-ebu ụzọ kwadebe ihe ga-edozi ya. Otu esi eme ya ziri ezi - na-akọwa ntuziaka n'ụzọ zuru ezu. Obere oge na-ere ere ị nwere ike ịchọta nkwusioru.

Ọnụ ego ọgwụ na-akwụ ụgwọ. Ampicillin anọwo na ahịa ọgwụ ọgwụ ogologo oge. Inwere ike izuta ya n’ejighi ndenye ọgwụ. Mbadamba ụrọ n’arọ nke iberibe iri abụọ nke 250 ga-efu gị ihe dị ka ru ru 20. Dabere na onye nrụpụta, ọnụahịa ahụ nwere ike ịgbago elu ma ọ bụ gbadaa ala. Nwere ike ịzụta kalama nwere ntụ ntụ maka injection maka 15 rubles. Ọdịnaya nke ampicillin na arịa dị otú ahụ nwere ike ịdị iche: 200, 250, 500 na 1000 milligrams.

Kedu ka Ampicillin si arụ ọrụ?

Ọgwụ "Ampicillin" na-ezo aka na ọgwụ mgbochi bakteria nke usoro penisillin. Ngwá ọrụ nwere ụdị ọrụ dịgasị iche, yabụ, a na-enyekarị ya ndị ọrịa na-enweghị mkpụrụ izizi maka nghọta. Ọgwụ na-egbochi mkpụkọ nke mkpụrụ ndụ, nke nwere mmetụta nje.

Ihe na-arụ ọrụ dị irè na-emegide ọtụtụ microorganisms aerobic, ma gram-nke ọma na gram-adịghị mma.Ogwu a nwere mwepu. Ọ nweghị ike ịkwụsịlata nje bacteria na-emepụta penicillinase. O di nwute, enwere otutu ndi ugbu a. Ọtụtụ mgbe, a na-emepụta ụmụ nje ndị ahụ n'ihi ojiji nke ọgwụ nje. Nke a na-egosikwa na ị nweghị ike iji aka gị mee ọgwụ, mana ịkwesịrị ịkpọtụrụ ndị dọkịta maka enyemaka.

Dochie anya Penicillin

Enwere m ike ịhọrọ analogues nke Ampicillin n'onwe m? Ndị dọkịta niile na ndị agụmakwụkwọ mmụta ọgwụ na-aza ajụjụ a n’otu: ọ bụghị. Nke bụ eziokwu bụ na ụfọdụ ndị nnọchi arụ nwere oke ọrụ dị iche iche; ha enweghị ike ịba uru n'otu ọnọdụ. Ọ bụrụ na n'ihi ihe ụfọdụ, ịgaghị eji ọgwụ Ampicillin enyere, ndị dọkịta ga-akwado ọgbọ ọhụrụ nke analogues ma ọ bụ nnọchi mgbe ochie.

Already maralarị na ọgwụ ahụ dị n’etiti penisilini otu. Ya mere, a na-ahọrọkarị ọgwụ ọzọ na ya. Ọ bụrụ na anyị na-ekwu maka ọgwụ ọgwụ dị na ya bụ ọgwụ ampicillin trihydrate, mgbe ahụ enwere ike ịpụta ọgwụ ndị a: Zetsil, Stanzacillin, Penodil, Purcillin, Pentrexil, na ndị ọzọ. Cheta na ndi n’ere ahia nwere ike imeputa ogwu a “Ampicillin”. Ya mere, a na-agbanwezikwa aha ahia ya: “Ampicillin trihydrate”, “Ampicillin sodium salt”, “Ampecillin Innotek”.

Nwere ike iji ọgwụ penicillin dochie ngwa ndị ọzọ na-arụ ọrụ. N'okwu a, analogues nke Ampicillin ga - enwe ihe ndị a na - arụ ọrụ:

amoxicillin (Augmentin, Ecobol, Flemoxin),
phenoxymethylpenicillin ("Clacil", "Ospen"),
oxacillin ("Prostaflin"),
piperacillin (Pizellin, Pipraks) na ndị ọzọ.

Ọzọ: ọgwụ nje na-ewu ewu

Analogues nke Ampicillin nwere ike inwe ihe ndị ọzọ na-arụ ọrụ. Ndị a bụ ọgwụ metụtara ndị ọzọ .. Ọtụtụ mgbe, a na-ahọ ha ka ha dochie anya mgbe a hụrụ onye ọrịa ọrịa nfụkasị ahụ. Medicinesfọdụ ọgwụ metụtara ọgbọ ọhụrụ nke ọgwụ nje. Yabụ, akụrụngwa "Ampicillin" analogues nwere ihe ndị a.

Cephalosporins: Cefatoxime, Ceftriaxone, Suprax.
Macrolides: Sumamed, Vilprafen, Klacid.
Tetracyclines: Minolexin, Unidox, Tigacil.
Aminoglycosides: "Gentamicin", "Neomycin", "Streptomycin".
Lincosamides: Nerolen, Dalacin, na ọtụtụ ndị ọzọ.

Ihe ngosi maka ojiji na mgbochi banyere iji Ampicillin

Ampicillin zuru oke, dị ka ọgwụ penicillin n’onwe ya, ka a na-edepụtara maka nje ndị na-akpata nje na akụkụ okuku ume: akwara, oyi baa. A na-eji ọgwụ ahụ eme ihe na omume ENT maka ọrịa nke imi, akpịrị na ntị. Edere ya maka ọrịa nje nke eriri afọ, eriri afọ. Ihe ngosiputa eji eme ihe bu oria, oria, oria, rheumatism.

Tupu iji ọgwụ mgbochi ọgwụ Ampicillin, analogues ma ọ bụ dochie anya ọgbọ ọhụrụ, ọ dị mkpa ịgụ ntuziaka ahụ. Lezienụ anya na contraindications na mmeghachi omume ọjọọ. Yabụ, dịka ọmụmaatụ, ọgwụ "Ampicillin" bụ ihe anabataghị iji ya mee ihe na elu uche ya, nfụkasị contraindications ndị ọzọ ga-abụkwa mononucleosis na-efe efe, ọrịa imeju na ọbara. Ọgwụ enweghị ọgwụ megide nje ọrịa.

Ampicillin: ntuziaka maka ojiji

Analogues nke ọgwụ ahụ nwere ụzọ eji eme ihe mgbe niile. Lezienụ anya na nke a. Iji ọgwụ nje na-ezighi ezi na-arụpụta nsonaazụ kachasị atụghị anya: site na enweghị ọgwụ ọjọọ ruo ọnwụ. Already maralarị na Ampicillin dị n'ụdị abụọ: mbadamba na inje (ị nwere ike ịchọta nkwusioru, mana ọ bụghị nke a ma ama). Etu esi eji ha eme ihe?

Edere ọgwụ na ogo nke 1 ruo 2 gram nke ihe na-arụ ọrụ kwa ụbọchị (kewara n'ime usoro 4). Maka umuaka, ka edeputara ogwu ahu dika aru ahu. A naghị atụ aro ya iji ọgwụ iji gwọọ ụmụ ọhụrụ.
N'ime ụdị injections, a na-enye ọgwụ ahụ maka ndị okenye na 250-500 mg kwa elekere anọ ma ọ bụ 6 (dabere na oria na ogo nke ọnọdụ ahụ). Maka ọgwụgwọ ụmụaka, a na-eji “Ampicillin” mee ihe site na 25 ruo 50 mg nke ọgwụ kwa kilogram nke ogo ahụ. Ọ dị mkpa ịkpachara anya na iwu ase mgbe ị na-etinye ọgwụ ntụtụ.

A na-ekpebi oge ọgwụgwọ ọ bụla n'otu n'otu, mana ọ gaghị erughị ụbọchị ise. Ogo kachasị nke onye toro eto kwa ụbọchị bụ gram 4 n'ụdị mbadamba na ụzọ iri ntụtụ.

Ọgwụgwọ n’oge ime na lactation

A na-anabata ụfọdụ analogues nke Ampicillin maka oge a dị ime, mana ọ bụ naanị dị ka ihe gosiri. N'ọnọdụ ka ukwuu, ọgwụ ndị a bụ ọgwụ penisilini. Enwere ike ịnye ndị nne n'ọdịnihu ka macrolides, mana nke a adịkarịghị. Enwere ike iji ọgwụ ahụ "Ampicillin" n'oge ime dị ka dọkịta nyere ya ndụmọdụ. Ọ dị mkpa ịkwụsị ị anụ ọgwụ nje naanị na ọkara nke mbụ. Maka ndị nne na-atụ anya, a na-enye ọgwụ ahụ n'otu usoro onunu ogwu dika otu usoro si dị.

Achọpụtala na ihe na - arụ ọrụ - ampicillin trihydrate - na - abanye n'ime mmiri ara. Ya mere, enwere ike ọgwụ na-abanye n’ahụ nwata ahụ. Y’oburu na achoro ọgwụgwọ n’oge a na-enye nwa ara, i kwesiri kpebie n ’imechi ara.

Ozi ogwu ozo

Ọ bụrụ na i jiri ọgwụ anapicillin na mbadamba ụrọ yana ọgwụ mgbochi izizi, mmetụta nke ọgwụ abụọ ahụ nwere ike ịbawanye ụba. Ya mere, ọ dị mkpa ịhọrọ ọgwụgwọ ziri ezi. Ejikọla Ampicillin na ọgwụ ọgbụgba ọhụụ na ihe ndị ọzọ yiri ya nke nwere nje nje.

Ebe ọgwụ a na - egbochi microflora eriri afọ, nke a nwere ike imebi ọrụ nke nri. Diuretics, nnwansi na lax, belata nnabata nke ọgwụ nje. Ascorbic acid, n'ụzọ dị iche, ọ na-abawanye ya. Biko mara na ọgwụ na-ebelata ịdị irè nke ọgwụ mgbochi ọnụ.

Mmetụta na-adịghị mma nke ọgwụgwọ

Ọgwụ a anaghị emetụta ọgwụ ọhụụ. Ọ naghị aga ọcha nhicha. Ya mere, ọgwụ nwere ike ibute ọtụtụ mmeghachi omume na-adịghị mma. Otu n'ime ha, ndị kasị ugboro:

afọ mgbu, ọgbụgbọ, ọgbụgbọ,
dysbiosis nke eriri afọ, afọ ọsịsa ma ọ bụ afọ ntachi,
fungal ọnya nke onu oghere, akụkụ ahụ, anụ ahụ,
mmeghachi omume nfụkasị ụdịrị edema, urticaria, ujo.

Allergy na Ampicillin

Analog nke “Ampicillin” (injections ma ọ bụ mbadamba - ọ nweghị ihe) sitere na penisillin otu, dị ka ọgwụ ahụ n'onwe ya, na-akpalite nfụkasị. Agbanyeghị, ọ nwere ike inwe ụdị ngosipụta dị iche iche. Ọ bụrụ na o nweela mgbe ụdị ihe a mere, ị kwesịrị icheta. N'ọdịnihu, mgbe ị na-ede ọgwụ ọgwụ nje, jide n'aka ịgwa dọkịta ahụ eziokwu.

Ihe nfụkasị ahụ kachasị na Ampicillin bụ ọnya akpụkpọ ahụ. O nwere obere ọnya ahụ dị ebe ahụ niile ma ọ bụ ebe dị iche. Ngwá ọrụ ahụ na-ebutekwa mgbu na nkwụchi nke anụ ahụ. Obere na-ahụkarị. Ọ bụrụ na nke ahu anataghi, ikwesiri ịguta dọkịta ozugbo o kwere omume, a takeụla ọgwụ ọzọ. Ọgwụ gbasara ọgwụgwọ gụnyere ọgwụ ịgba ọgwụ na ọgwụ ọgwụ. Ọ dịkwa mkpa ịhọrọ analọg nke ọgwụ nje.

Ampicillin na mmanya

Kedu ihe nkuzi a na-ekwu banyere ọgwụ "Ampicillin"? Analogues nke usoro penicillin, yana ọgwụ nje akọwara n'onwe ya, anaghị akwado ị combụ mmanya na-aba n'anya. Ngwakọta ndị dị otú a na-eme ka o nwekwuo ike inweta nsonaazụ. Na mgbakwunye, ethanol tinyere Ampicillin na-emetụta imeju na afọ. Nchikota nke kemịkal nwere ike mebie mmetụta nke ọgwụ.

N'agbanyeghị eziokwu a, ụfọdụ ndị na - azụ ahịa jisiri ike wụfee iko abụọ n'ime oge ọgwụgwọ. Ndị ọrịa na-ekwu na ọ nweghị ihe ọjọọ mere ha. N'ezie, nke a bụ ihu ọma. Ikekwe ihe ga-esi na ya pụta ga-apụta ìhè n'ọdịnihu.

Ọkpụkpụ ọgwụ penicillin nke na-agbasa, na -akpata ya

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

Ọgwụ ọcha, ewepụghị-cylindrical udi na chamfer na notch.

Ndị ọkachamara: stachite nduku, magnesium stearate, talc, polyvinylpyrrolidone, tween-80.
10 PC. - ngwugwu ọnya (1) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu n’enweghi akara ekwentị (1) - ngwugwu nke kaadiboodu.

Ntụ ntụ maka nkwụsị ọnụ na-acha ọcha na-acha odo odo na-acha, na-enwe isi na-esi ísì, kwadebere nkwusioru ọcha na -acha odo.

Ndị na-ahụ maka ihe: polyvinylpyrrolidone, 1-aquous godiamate sodium gupamate ma ọ bụ phosphate anhydrous disodium phosphate, Trilon B, dextrose, vanillin, isi nri aromat (rasberi), shuga a nụchara anụcha ma ọ bụ shuga a nụchara anụcha.
60 g (5 g nke ihe na-arụ ọrụ) - karama (1) zuru oke na ngaji usoro onunu - ngwugwu nke kaadiboodu.

Karama 10 ml (1) - ngwugwu nke kaadiboodu.
Karama 10 ml (10) - ngwugwu nke kaadiboodu.
Karama 10 ml (50) - igbe kaadiboodu.

Ntụ ntụ maka iji dozie nsị ọcha, hygroscopic.

Kalama nwere olu nke 10 ma obu 20 ml (1) - ngwugwu nke kaadiboodu.
Karama jiri olu nke 10 ma obu 20 ml (10) - ngwugwu nke kaadiboodu.
Karama 10 ma ọ bụ 20 ml (50) - igbe kaadiboodu.

Omume ọgwụ

Ọgwụ nje na alụ ọgụ semisynthetic penicillins nwere ụdị ọrụ dị iche iche. Ọ nwere mmetụta nke nje na-egbochi mgbochi nke mgbidi sel ahụ.

Arụ ọrụ na-emegide gram-nti aerobic nje: Staphylococcus spp. (ewezuga penicillinase na-emepụta nsogbu), Streptococcus spp. (gụnyere Enterococcus spp.), Listeria monocytogenes, gram-ọjọọ nje aerobic: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, ụfọdụ ụdị ọrịa Haemophilus influenzae.

Penicillinase na-ebibi ya. Acid na-eguzogide.

Mlọ ọgwụ

Mgbe nchịkwa ọnụ gasịrị, a na-etinye ya nke ọma na eriri afọ, ọ bụghị ibibi gburugburu acidic nke afọ. Mgbe nchịkwa parenteral (i / m na m / v) a na-ahụta ya n’ọbara n’ogwe ike.

Ọ bara nke ọma na akwara na ahụ mmadụ, a na-ahụ ya na ọgwụgwọ anụ ahụ na pleural, peritoneal and synovial fluid. Penetrates site na ihe mgbochi placental. Ọ na-abanye n'ụzọ na-adịghị mma site na mgbochi ụbụrụ ọbara, ma, ọ nwere ọnya ụbụrụ nke ụbụrụ, oke nke BBB na-abawanye nke ọma.

30% nke ampicillin bụ metabolized na imeju.

T 1 / 1-2 - awa nke 1-1.5. Ana ewere ya na mmamịrị mee ya, ma a na -emepụta oke ọgwụ na ọgwụ agbanwebeghị na mmamịrị. Akụkụ ụfọdụ na bile.

Repeatedlọ ọgwụ ugboro ugboro anaghị agakọ.

Ọrịa na-efe efe na mkpali kpatara microorganisms nwere mmetụta nke ampicillin, gụnyere:

- ọrịa akwara umeji (gụnyere ọnya afọ, oyi baa, akpa ume),

- ọrịa nke akụkụ akụkụ ENT (gụnyere tonsillitis),

- ọrịa biliary tract (gụnyere cholecystitis, cholangitis),

- urinary tract na-efe efe (gụnyere pyelitis, pyelonephritis, cystitis),

- eriri afọ (ọrịa eriri afọ),

- ofufe ọrịa nke anụ ahụ na anụ ahụ dị nro,

- sepsis, septic endocarditis,

Mkparịta ụka ọgwụ ọjọọ

Probenecid na iji Ampicillin-AKOS na -ebelata tubular secretion nke ampicillin, n'ihi nsonaazụ ya na plasma ọbara na-abawanye na ohere nke nsonaazụ uto.

Site na iji Ampicillin-AKOS na-emeghariri oge, enwere ohere nke nchapu akpukpo aru.

Iji otu oge eji Ampicillin-AKOS, ịdị irè nke ọgwụ mgbochi ọgwụ a na-egbochi estrogen na-ebelata.

Site na iji Ampicillin-AKOS n'otu oge, ịdị irè nke ọgwụ nje aminoglycoside na-abawanye.

Ntụziaka pụrụ iche

Na usoro ọgwụgwọ Ampicillin, ọ dị mkpa ilekọta imeju na akụrụ oge niile. Ọ bụrụ na ha na-emebi, usoro ogwu usoro kwesịrị ka edogharia ya.

Doses dị elu nke ọgwụ ọjọọ na ndị ọrịa nwere akụrụ gbasara akwara nwere ike ịnwe nsí na-egbu egbu na sistemụ akwara.

Ampicillin analogues

N'ime analogues nke Ampicillin, enwere ike ịhapụ ọgwụ ndị na-esonụ:

Ampicillin-AKOS,
Ampicillin sodium nnu,
Ampicillin-Ferein,
Puricillin
Zetsil
Standacillin,
Penodil.

Usoro na ọnọdụ nchekwa

Acquainmara mbu: ụdị ntọhapụ, ọnụ ahịa na ihe mejupụtara

Kedu ka Ampicillin si arụ ọrụ?

Ihe na-arụ ọrụ dị irè na-emegide ọtụtụ microorganisms aerobic, ma gram-nke ọma na gram-adịghị mma. Ogwu a nwere mwepu. Ọ nweghị ike ịkwụsịlata nje bacteria na-emepụta penicillinase. O di nwute, enwere otutu ndi ugbu a. Ọtụtụ mgbe, a na-emepụta ụmụ nje ndị ahụ n'ihi ojiji nke ọgwụ nje. Nke a na-egosikwa na ị nweghị ike ị selfụ ọgwụ n'onwe gị, mana ịkwesịrị ịkpọtụrụ ndị dọkịta maka enyemaka.

Dochie anya Penicillin

Enwere m ike ịhọrọ analogues nke Ampicillin n'onwe m? Ndị dọkịta niile na ndị agụmakwụkwọ mmụta ahụike zara ajụjụ a n’otu: ọ bụghị. Nke bụ eziokwu bụ na ụfọdụ ndị nnọchi arụ nwere oke ọrụ dị iche iche; ha enweghị ike ịba uru n'otu ọnọdụ. Ọ bụrụ na n'ihi ihe ụfọdụ, ịgaghị eji ọgwụ Ampicillin edepụtara, dọkịta ga-akwado ọgbọ ọhụụ nke analogues ma ọ bụ nnọchi mgbe ọ bụla.

Already maralarị na ọgwụ ahụ dị n’etiti penisilini otu. Ya mere, a na-ahọrọkarị ọgwụ ọzọ site na ya.Ọ bụrụ na anyị na-ekwu maka ọgwụ ọgwụ dị na ya bụ ọgwụ ampicillin trihydrate, mgbe ahụ enwere ike ịpụta ọgwụ ndị a: Zetsil, Stanzacillin, Penodil, Purcillin, Pentrexil, na ndị ọzọ. Cheta na ndi n’ere ahia nwere ike imeputa ogwu a “Ampicillin”. Ya mere, a na-agbanwezikwa aha ahia ya: “Ampicillin trihydrate”, “Ampicillin sodium salt”, “Ampecillin Innotek”.

Nwere ike iji ọgwụ penicillin dochie ngwa ndị ọzọ na-arụ ọrụ. N'okwu a, analogues nke Ampicillin ga - enwe ihe ndị a na - arụ ọrụ:

amoxicillin (Augmentin, Ecobol, Flemoxin),
phenoxymethylpenicillin ("Clacil", "Ospen"),
oxacillin ("Prostaflin"),
piperacillin (Pizellin, Pipraks) na ndị ọzọ.

Ọzọ: ọgwụ nje na-ewu ewu

Cephalosporins: Cefatoxime, Ceftriaxone, Suprax.
Macrolides: Sumamed, Vilprafen, Klacid.
Tetracyclines: Minolexin, Unidox, Tigacil.
Aminoglycosides: "Gentamicin", "Neomycin", "Streptomycin".
Lincosamides: Nerolen, Dalacin, na ọtụtụ ndị ọzọ.

Ihe ngosi maka ojiji na mgbochi banyere iji Ampicillin

Ampicillin: ntuziaka maka ojiji

Edere ọgwụ na ogo nke 1 ruo 2 gram nke ihe na-arụ ọrụ kwa ụbọchị (kewara n'ime usoro 4). Maka umuaka, ka edeputara ogwu ahu dika aru ahu. A naghị atụ aro ya iji ọgwụ iji gwọọ ụmụ ọhụrụ.
N'ime ụdị injections, a na-enye ọgwụ ahụ maka ndị okenye na 250-500 mg kwa elekere anọ ma ọ bụ 6 (dabere na oria na ogo nke ọnọdụ ahụ). Maka ọgwụgwọ ụmụaka, a na-eji “Ampicillin” mee ihe site na 25 ruo 50 mg nke ọgwụ kwa kilogram nke ogo ahụ. Ọ dị mkpa ịkpachara anya na iwu ase mgbe ị na-etinye ọgwụ ntụtụ.

Ọgwụgwọ n’oge ime na lactation

Ozi ogwu ozo

Mmetụta na-adịghị mma nke ọgwụgwọ

Ọgwụ a anaghị emetụta ọgwụ ọhụụ. Ọ naghị aga ọcha nhicha. Ya mere, ọgwụ nwere ike ibute ọtụtụ mmeghachi omume na-adịghị mma. Otu n'ime ha, ndị kasị ugboro:

afọ mgbu, ọgbụgbọ, ọgbụgbọ,
dysbiosis nke eriri afọ, afọ ọsịsa ma ọ bụ afọ ntachi,
fungal ọnya nke onu oghere, akụkụ ahụ, anụ ahụ,
mmeghachi omume nfụkasị ụdịrị edema, urticaria, ujo.

Allergy na Ampicillin

Ampicillin na mmanya

Ọkpụkpụ ọgwụ penicillin nke na-agbasa, na -akpata ya

Ihe eji arụ ọrụ

Ampicillin (n'ụdị trihydrate) (ampicillin)

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

Ọgwụ ọcha, ewepụghị-cylindrical udi na chamfer na notch.

Ntụ ntụ maka nkwụsị ọnụ na-acha ọcha na-acha odo odo na-acha, na-enwe isi na-esi ísì, kwadebere nkwusioru ọcha na -acha odo.

Karama 10 ml (1) - ngwugwu nke kaadiboodu.
Karama 10 ml (10) - ngwugwu nke kaadiboodu.
Karama 10 ml (50) - igbe kaadiboodu.

Ntụ ntụ maka iji dozie nsị ọcha, hygroscopic.

Kalama nwere olu nke 10 ma obu 20 ml (1) - ngwugwu nke kaadiboodu.
Karama jiri olu nke 10 ma obu 20 ml (10) - ngwugwu nke kaadiboodu.
Karama 10 ma ọ bụ 20 ml (50) - igbe kaadiboodu.

Omume ọgwụ

Ọgwụ nje na alụ ọgụ semisynthetic penicillins nwere ụdị ọrụ dị iche iche. Ọ nwere mmetụta nke nje na-egbochi mgbochi nke mgbidi sel ahụ.

Penicillinase na-ebibi ya. Acid na-eguzogide.

Mlọ ọgwụ

30% nke ampicillin bụ metabolized na imeju.

T 1 / 1-2 - awa nke 1-1.5. Ana ewere ya na mmamịrị mee ya, ma a na -emepụta oke ọgwụ na ọgwụ agbanwebeghị na mmamịrị. Akụkụ ụfọdụ na bile.

Repeatedlọ ọgwụ ugboro ugboro anaghị agakọ.

Ọrịa na-efe efe na mkpali kpatara microorganisms nwere mmetụta nke ampicillin, gụnyere:

- ọrịa akwara umeji (gụnyere ọnya afọ, oyi baa, akpa ume),

- ọrịa nke akụkụ akụkụ ENT (gụnyere tonsillitis),

- ọrịa biliary tract (gụnyere cholecystitis, cholangitis),

- urinary tract na-efe efe (gụnyere pyelitis, pyelonephritis, cystitis),

- eriri afọ (ọrịa eriri afọ),

- ofufe ọrịa nke anụ ahụ na anụ ahụ dị nro,

- sepsis, septic endocarditis,

Ihe ngbanwe

- Nnukwu ọgwụ mgbochi sitere na penisillin otu yana ọgwụ mgbochi ọgwụ betalactam ndị ọzọ.

- Nnukwu nsogbu nke ọrụ imeju (maka iji ya mee ihe).

Nịm n'otu n'otu dabere ogo usoro ahụ, ọnọdụ nke ọrịa ahụ na ọnụnọ nke pathogen.

Mgbe a na -ewere ya ọnụ, otu ọgwụ maka ndi okenye bụ 250-500 mg, kwa ụbọchị bụ 1-3 g. Oke kachasị kwa ụbọchị bụ 4 g.

Maka umuaka Edere ọgwụ a na ọgwụ kwa ụbọchị nke 50-100 mg / kg, ụmụaka na-eri ihe ruru kilogram 20 - 12.5-25 mg / n'arọ.

A na-ekewa ụbọchị kwa ụbọchị ụzọ 4. Oge ọgwụgwọ ọ dabere na ogo ọrịa yana ịdị irè nke ọgwụgwọ ahụ.

A na-ewere mbadamba okwu ọnụ, n'agbanyeghị nri a na-eri.

Iji kwadebe nkwusioru ahụ, a na-agbakwunye 62 ml nke mmiri distilled na vile ntụ ntụ. A na-eji ntụpọ pụrụ iche nke nwere akara aha abụọ kwụọ ụgwọ: nke dị ala kwekọrọ na 2.5 ml (125 mg), nke dị elu - 5 ml (250 mg). Ekwesịrị iji mmiri kwụọ nkwusi ahụ.

Na nchịkwa parenteral (i / m, iv / jet ma ọ bụ iv drip) otu ngafe maka ndi okenye bụ 250-500 mg, ọgwụ kwa ụbọchị bụ 1-3 g, na ọrịa dị egwu, enwere ike ịbawanye ọgwụ kwa ụbọchị ruo 10 g ma ọ bụ karịa.

Umu amụrụ ọhụrụ ọgwụ ọgwụ na a ọgwụ kwa ụbọchị nke 100 mg / n'arọ, ụmụ nke ọgbọ ndị ọzọ - 50 mg / n'arọ. N'ime ọrịa dị egwu, enwere ike okpukpu abụọ nke ọgwụ ndị a.

A na-ekewa usoro ubọchị ahụ kwa ụbọchị n'ime 4-6 iji oge dị n'agbata awa isii na isii. Ogologo oge nke ngwa nke IV bụ ụbọchị 5-7, yana ntụgharị (ọ bụrụ na ọ dị mkpa) na ntinye ozi IM.

A na-akwado ihe ngwọta maka nchịkwa intramuscular site na ịtinye mmiri 2 ml mmiri iji gbanye ihe dị na vial ahụ.

Maka ogwu iv, a na-agbari otu ọgwụ ọgwụ (ọ dịghị ihe karịrị 2 g) na 5-10 ml mmiri maka ntụtụ ma ọ bụ ọgwụ isotonic ma gbanye nwayọọ nwayọọ ruo minit 3-5 (1-2 g maka minit 10-15). N’otu mkpụrụ ọgwụ karịrị 2 g, a na-a drugụ ọgwụ ahụ intravenously. Maka nke a, otu ọgwụ ọgwụ (2-4 g) na-agbari na 7.5-15 ml mmiri maka ntụtụ, mgbe ahụ, a na-agbakwunye ihe a na-akpata na 125-250 ml nke sodium chloride solution ma ọ bụ 5-10% ma gbanye ya na ọsọ 60-80 tụlee / min Site na iv drip na ụmụaka, a na-eji 5-10% glucose edozi (30-50 ml dabere na afọ) dị ka ihe mgbaze.

A na-eji ihe ngwọta ozugbo akwadebe.

Nsonaazụ

Mmeghachi omume nfụkasị ahụ: ọnya ọnya, urticaria, ede ede Quincke, pruritus, exfoliative dermatitis, erythema multiforme, n'ọnọdụ ndị dị obere - ujo anacticlactic.

Site na nri digestive: ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, glossitis, stomatitis, pseudomembranous colitis, eriri afọ dysbiosis, ịba ụba ọrụ nke transminases hepatic.

Site na sistemụ hemopoietic: anaemia, leukopenia, thrombocytopenia, agranulocytosis.

Mmetụta n'ihi nsonji na-agwọ ọrịa: candidiasis na-aralụ ọnụ, candidiasis na-egbu egbu.

Dodoụbiga ya ókè

Mkparịta ụka ọgwụ ọjọọ

Probenecid na iji Ampicillin-AKOS na -ebelata tubular secretion nke ampicillin, n'ihi nsonaazụ ya na plasma ọbara na-abawanye na ohere nke nsonaazụ uto.

Site na iji Ampicillin-AKOS na-emeghariri oge, enwere ohere nke nchapu akpukpo aru.

Iji otu oge eji Ampicillin-AKOS, ịdị irè nke ọgwụ mgbochi ọgwụ a na-egbochi estrogen na-ebelata.

Site na iji Ampicillin-AKOS n'otu oge, ịdị irè nke ọgwụ nje aminoglycoside na-abawanye.

Ntụziaka pụrụ iche

Site na ịkpachapụ anya na imegide nzụlite n'otu oge nke ihe ndị na - akpata nkụda mmụọ, a ga-edenye ọgwụ maka ụkwara ume ọkụ, ọrịa hay na ọrịa ndị ọzọ.

N'ime usoro iji Ampicillin-AKOS, usoro nlezianya nke gbasara akụrụ, imeju na eserese ọbara dị mkpa.

N'ihe banyere ọrịa imeju, a ga-eji ọgwụ ahụ naanị n'okpuru nchịkwa nke ọrụ imeju.

Ndị ọrịa nwere nsogbu gbasara akụrụngwa chọrọ mgbazi nke usoro usoro usoro ọgwụgwọ dabere na QC.

Mgbe ị na-eji ọgwụ ahụ na ọnụọgụ dị elu na ndị ọrịa nwere ọrịa akụrụ, nsonaazụ ndị na-egbu egbu na sistemụ akwara dị n'etiti.

Mgbe ị na-a theụ ọgwụ maka ọgwụgwọ nke sepsis, a ga-ekwe omume mmeghachi azụ nke bacteriolysis (mmeghachi omume Yarish-Herxheimer).

Ọ bụrụ na mmeghachi omume nfụkasị ahụ na-eme n'oge a na-eji Ampicillin-AKOS, ekwesịrị ịkwụsị ọgwụ a ma belata ọgwụ.

Ndị ọrịa na-adịghị ike nke ị withụ ọgwụ ogologo oge nwere ike ịmalite ụdị nnabata nke microorganisms na-eguzogide ọgwụ ampicillin.

Iji gbochie mmepe nke candidiasis n'otu oge na Ampicillin-AKOS, ekwesịrị inye nystatin ma ọ bụ levorin, yana vitamin nke otu B na C.

Ime na lactation

O kwere omume ị duringụ ọgwụ n’oge afọ dị ka e si gosipụta n’ọnọdụ ndị ahụ ebe abamuru nke nne karịrị ihe ize ndụ nke nwa ebu n’afọ.

Ampicillin na-apụ apụ n’ime mmiri ara ara n’obere ala. Ọ bụrụ na ọ dị mkpa, ka iji ọgwụ eme ihe n’oge a na-enye nwa kwesịrị ikpebi nkwụsị nke inye ya ara.

Site na ịrụ ọrụ ọrụ imeju

Parenteral jiri contraindicated na ọrụ imeju na-arụ ọrụ nke ukwuu.

Usoro na ọnọdụ nchekwa

Ndepụta B. Ekwesịrị ịchekwa ọgwụ ahụ na ebe kpọrọ nkụ, ọchịchịrị, mbadamba nkume na ntụ ntụ maka ịkwadebe nkwusioru - na okpomọkụ nke 15 Celsius ruo 25 Celsius C, ntụ ntụ maka ịkwadebe ihe ngwọta maka ntụtụ - na okpomọkụ agaghị akarị 20 Celsius. Ndụ nchekwa nke mbadamba ụrọ, ntụ ntụ maka nkwusioru na ntụ ntụ maka ngwọta maka injection bụ afọ 2.

Ekwesiri idochi nkwusioru a kwadebere na friji ma ọ bụ n'ọnụ ụlọ dị ọkụ maka ihe na-erughị ụbọchị 8. Ihe edozi akwadoro maka ochichi m / m na iv edoghi nchekwa.

Usoro ahịa ọgwụ ahịa

Ogwu gi bu ogwu.

Ntụziaka maka ojiji. Ihe mgbochi na ụdị nke ịhapụ.

Ọkpụkpụ ọgwụ mgbochi dị ukwuu site na otu nke penisilini semisynthetic. Ọ na-eme ihe na-egbochi ahụhụ, na-egbochi njikọ nke mgbidi sel. Ọrụ megide microorganisms gram-gram: cocci - Staphylococcus spp. (ewezuga penicillinase na-emepụta nsogbu), Streptococcus spp. (gụnyere Enterococcus), nje ndị na - emeghị emezi - Listeria monocytogenes. Ampicillin na - arụkwa ọrụ megide microorganisms gram na - adịghị mma: aerobic - Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, ụfọdụ ụdị ọrịa Haemophilus influenzae. Ampicillin na-ebibi penicillinase. Acid na-eguzogide.

Mgbe nchịkwa ọnụ gasịrị, ọ na-etinye obi gị dum na ngọngọ nri. A na-ekesa Ampicillin n'ọtụtụ akụkụ na anụ ahụ. Ọ na-abanye na Plasenta, na-esighi ike banye na BBB. Site na mbufụt nke meninges, ikike nke BBB na-abawanye n'ike n'ike. 30% nke ampicillin bụ metabolized na imeju. A na-akpụpụ ya na mmamịrị na bile.

Ọrịa na-efe efe na mkpali kpatara microorganisms nwere mmetụta nke ampicillin: incl. ofufe ọrịa nke ntị, akpịrị, imi, ọrịa odontogenic, ọrịa bronchopulmonary, ọrịa na-adịghị ala ala nke ọrịa genitourinary, eriri afọ na-efe efe (gụnyere salmonellosis, cholecystitis), ọrịa gynecological, meningitis, endocarditis, septicemia, sepsis, rheumatism, erysipelas, fever fever, fever fever, fever fever na-efe efe nke anụ ahụ na anụ ahụ dị nro.

Nịm n'otu n'otu dabere ogo usoro ahụ, ọnọdụ nke ọrịa ahụ na ọnụnọ nke pathogen.
Mgbe ejiri ọnụ kwuo okwu maka ndị okenye, otu ọgwụ bụ 250-500 mg, ugboro ole nchịkwa bụ 4 ugboro / ụbọchị. Withmụaka nwere aru dị kilogram iri abụọ na abụọ ka etinyere 12.5-25 mg / n'arọ kwa elekere isii.
Maka intramuscular, nchịkwa ọgbụgba, otu ọgwụ maka ndị okenye bụ 250-500 mg kwa elekere 4-6. Maka ụmụaka, otu mkpụrụ ọgwụ bụ 25-50 mg / kg.
Oge ọgwụgwọ ọ dabere na ọnọdụ nke ọrịa ahụ na njirimara nke usoro ọrịa ahụ.
Obere pere mpe: maka ndị okenye, ọgwụ kwa ụbọchị maka nchịkwa ọnụ bụ 4 g, ọgwụ kwa ụbọchị maka nchịkwa mgbochi na intramuscular bụ 14 g.

Mmeghachi omume nfụkasị: urticaria, erythema, edema nke Quincke, rhinitis, conjunctivitis, adịkarịghị - ahụ ọkụ, nkwonkwo mgbu, eosinophilia, dị ụkọ - ujo anaphylactic.
Site na usoro nri: ọgbụgbọ, ọgbụgbọ, dysbiosis eriri afọ, ọnya na-akpata C. nsogbu.
Mmetụta nsonaazụ sitere na chemotherapeutic: candidiasis nke oghere ọnụ, candidiasis nke nwanyị.

Hypersensitivity na ampicillin na penicillins ndị ọzọ, ọrụ imeju na-arụ ọrụ.

Ime na lactation

Ikekwe ojiji nke ampicillin n'oge ime dị ka ihe ngosi. Ampicillin na-apụ apụ n’ime mmiri ara ara n’obere ala. Ọ bụrụ na ọ dị mkpa, iji ampicillin n’oge a na-ehi ụra kwesịrị ikpebi ịkwụsị n ’ara.

N'ime usoro ọgwụgwọ na ampicillin, usoro nlezianya maka ọrụ nke akụrụ, imeju na elu ọbara dị mkpa. Ndị ọrịa nwere nsogbu gbasara akụrụngwa chọrọ mgbazi nke usoro dosing dị ka ụkpụrụ QC si dị.
Mgbe ị na-eji usoro ọgwụ dị elu na ndị ọrịa nwere akụrụ egwu, nsonaazụ nsị na usoro akwara dị n'etiti ga-ekwe omume.
Mgbe ejiri ampicillin mee ihe na ndị ọrịa nwere bacteremia (sepsis), mmeghachi azụ nke bacteriolysis (mmeghachi omume Yarish-Herxheimer).

Probenecid na ojiji a na-ejikọ ya na ampicillin belata tubular secretion nke nke ikpeazụ, na-ebute mmụba nke mkpokọta nke ampicillin na plasma ọbara na oke ihe egwu nke nsonaazụ nsị.
N'iji ojiji nke ampicillin n’otu ọgwụ a na-a containingụ ọgwụ ọgwụ estrogen, enwere mbelata na arụmọrụ ha, ikekwe n’ihi na-ebelata ọbara mgbasa oke nke estrogens.

Ọnọdụ nchekwa na oge Achekwaa na nkụ, ọchịchịrị, mbadamba nkume na ntụ ntụ maka nkwadebe nkwusioru - na okpomọkụ nke 15 Celsius ruo 25 Celsius C, ntụ ntụ maka ngbanye ogwu ogbugba - na-adịghị oke 20 Celsius.

Ndụ shelf bụ afọ 2.
Ekwesiri idochi nkwusioru a kwadebere na friji ma ọ bụ n'ọnụ ụlọ dị ọkụ maka ihe na-erughị ụbọchị 8. Ihe edozi akwadoro maka ochichi / iv na iv edoghi nchekwa.