Rosinsulin P, S, M

Onye na-ahụ maka hypoglycemic, insulin na-adị mkpụmkpụ. Withme ka otu onye nnabata nke akpụkpọ ahụ dị na sel na - emekọ ihe, na - eme ka ihe nnabata nke insulin. Site na ịba ụba njikọta nke cAMP (na abụba abụba na akwara akwara) ma ọ bụ banye n'ime sel (akwara), insulin receptor complex na-akpali usoro intracellular, gụnyere njikọ nke ọtụtụ enzymes isi (gụnyere hexokinase, pyruvate kinase, glycogen synthetase).

A na-eme ka mbelata glucose na ọbara na-abawanye site na mmụba na ntinye ya na intracellular, nnabata nke ukwuu na nro nke anụ ahụ, mkpali nke lipogenesis, glycogenogenesis, njikọ protein, yana mbelata nke mmịpụta nke glucose site na imeju (ibelata na mmebi nke glycogen).

Mmalite nke ime bụ mgbe nkeji iri atọ gasịrị, oke kachasị na-arụ ọrụ bụ mgbe awa 1-3 gachara, oge ihe a ga-eme bụ awa asatọ.

Usoro usoro onunu ogwu

A na-ekpebi ogo na ụzọ nchịkwa nke ọgwụ ahụ n'otu n'otu n'ọnọdụ ọ bụla dabere na ọdịnaya glucose dị n'ọbara tupu iri nri na 1-2 awa mgbe ị risịrị nri, yana dabere na ogo glucosuria na njiri nke ọrịa ahụ.

Dịka iwu, a na-achịkwa s / c nkeji iri na abụọ tupu iri nri. A na-agbanwe saịtị ndị ịgba agba oge ọ bụla. Ọ bụrụ na ọ dị mkpa, a na-ahapụ nchịkwa IM ma ọ bụ nke IV.

Enwere ike ijikọ ya na insulins na-eme ogologo oge.

Mmetụta akụkụ

Mmeghachi omume nfụkasị: urticaria, angioedema, ahụ ọkụ, mkpụmkpụ ume, mbelata ọbara mgbali elu.

Site na usoro endocrine: hypoglycemia nwere ngosipụta dịka pallor, ịba ụba ọsụsọ, palpitations, ọgba aghara ụra, ịma jijiji, nsogbu akwara ozi, mmeghachi omume immunological na insulin mmadụ, mmụba na titer nke ọgwụ mgbochi insulin na mmụba na-esote glycemia.

Site n'akụkụ akụkụ ahụ nke ọhụụ: nkwarụ anya na-adịghị ala ala (ọ na-abụkarị mmalite nke usoro ọgwụgwọ).

Mmeghachi omume mpaghara: hyperemia, itching na lipodystrophy (atrophy ma ọ bụ hypertrophy nke abụba subcutaneous) na ntinye ahụ.

Ndị ọzọ: na mmalite ọgwụgwọ, edema ga-ekwe omume (ịgafe usoro ọgwụgwọ na-aga n'ihu).

Ime na lactation

N'oge afọ ime, ọ dị mkpa iburu n'uche mbelata mkpa nke insulin na ọkara nke mbụ ma ọ bụ mmụba nke ọnwa nke abụọ na nke atọ. N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu.

N'oge a na-enye nwa ara, onye ọrịa chọrọ nleba anya kwa ụbọchị ruo ọtụtụ ọnwa (ruo mgbe ebilite mkpa nke insulin).

Ntụziaka pụrụ iche

Site na ịkpachapụ anya, a na-eme nhọrọ ọgwụ ahụ na ndị ọrịa nwere ọrịa ụbụrụ n'oge gara aga dị ka ụdị ischemic yana ụdị ajọ ọrịa obi.
Mkpa insulin nwere ike ịgbanwe n'ọnọdụ ndị a: mgbe ị na-agbanwe ụdị insulin ọzọ, mgbe ị na-agbanwe nri, afọ ọsịsa, vomiting, mgbe ị na-agbanwe olu arụmọrụ nkịtị, na ọrịa nke akụrụ, imeju, pituitary, gland thyroid, mgbe ị na-agbanwe ebe nsị.
Requiredme mgbanwe insulin kwa ụfọdụ maka ọrịa na-efe efe, nsị thyroid, ọrịa Addison, hypopituitarism, ọdịda akụrụ na-adịghị ala ala, yana ọrịa mellitus na ndị ọrịa karịa afọ 65.

Transferbufe onye ọrịa na insulin mmadụ kwesịrị ịdị na-enyocha ya nke ọma ma rụọ ya naanị n'okpuru nlekọta dọkịta.

Ihe kpatara hypoglycemia nwere ike ịbụ: insulin overdose, ọgwụ iji ọgwụ eme ihe, ite mmiri, vomiting, afọ ọsịsa, nchekasị anụ ahụ, ọrịa na-ebelata mkpa insulin (ọrịa akụrụ siri ike na ọrịa imeju, yana hypofunction nke adrenal cortex, pituitary ma ọ bụ thyroid gland), mgbanwe nke ebe ịgba. (dịka ọmụmaatụ, anụ dị n’afọ, ubu, apata ụkwụ), yana ịmekọrịta ọgwụ ndị ọzọ. O kwere omume belata mkpụkọ glucose dị n'ọbara mgbe ị na-ebufe onye ọrịa site na insulin anụmanụ n'ime insulin nke mmadụ.

Ekwesịrị ịgwa onye ọrịa banyere ihe mgbaàmà hypoglycemic ala, banyere ihe ịrịba ama mbụ nke ọrịa mamịrị na banyere mkpa ọ ga-agwa dọkịta banyere mgbanwe niile na ọnọdụ ya.

N'ihe banyere hypoglycemia, ọ bụrụ na onye ọrịa maara, a na-edenye ya dextrose n'ime, s / c, i / m ma ọ bụ iv in glucagon injection ma ọ bụ iv hypertonic dextrose solution. Site na ntinye nke hypoglycemic coma, 20-40 ml (ihe ruru 100 ml) nke mmiri 40% dextrose na-abanye n'ime iyi ruo mgbe onye ọrịa ahụ si na Coma pụta.

Ndị ọrịa nwere ọrịa shuga nwere ike ịkwụsị ntakịrị hypoglycemia nke ha na-enwe site na iri shuga ma ọ bụ nri dị oke na carbohydrates (a na-atụ aro ka ndị ọrịa nwee mgbe ọ dịkarịa ala 20 g sugar).

Mbelata mmanya na-egbu egbu n'ime ndị ọrịa na-anata insulin.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

Omume nke ịmalite hypoglycemia nwere ike imebi ikike nke ndị ọrịa ịnya ụgbọ ala ma jiri usoro rụọ ọrụ.

Mkparịta ụka ọgwụ ọjọọ

A na - eme ka mmetụta hypoglycemic dị na sulfonamides (gụnyere ọgwụ hypoglycemic nke ọgwụ, sulfonamides), MAO inhibitors (gụnyere furazolidone, procarbazine, selegiline), carbon anhydrase inhibitors, ACE inhibitors, ndị na - egbochi NSAIDs (gụnyere salicylides), anabolic (gụnyere stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, njikere lithium, pyridoxine, quinidine, quinine, chlo, etin, chlo, etin, chlo.

Glucagon, GCS, histamine H 1 na-anabata ihe mgbochi, mgbochi mkpịsị onwa, estrogens, thiazide na "loop" diuretics, mkpọchi calcium na-egbochi, ọmịiko, homonụ thyroid, tricyclic antidepressants, heparin, morphine diazropin belata mmetụta hypoglycemic mmetụta. , marijuana, nicotine, phenytoin, epinephrine.

Beta-blockers, reserpine, octreotide, pentamidine nwere ike ịkwalite ma belata mmetụta hypoglycemic nke insulin.

Ojiji nke beta-igbochi, clonidine, guanethidine ma ọ bụ reserpine nwere ike kpuchie mgbaàmà hypoglycemia.

N ’ogwu ọgwụ ekwekọghị na ọgwụ nke ọgwụ ndị ọzọ.

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

Ọ dị na usoro atọ:

1. P - obere ọrụ, enweghi agba na idozi ụzọ.
2. C - oge ọkara, ihe nkwụchi nke agba ọcha ma ọ bụ milky agba.
3. M - mix 30/70, nke abụọ. Ọkara na mmalite ngwa ngwa nke nsonaazụ, nkwusioru.

Ihe mejupụtara ya gụnyere:

• 100 IU nke insulin injinini nke mmadụ.
• sọlfọ protamine,
• sodium hydrogen phosphate mmiri riri,
• crystalline phenol,
• metacresol
• glycerol (glycerin),
• mmiri maka ịgba ntụtụ.

Ndị nwere ihe mejupụtara ya na ụdị ahụ dịtụ iche maka ụdị ọ bụla. Rosinsulin M nwere insulin biphasic - soluble + isophane.

A na-enweta ya na karama (iberibe 5 ml 5) na katrized (5 iberibe 3 ml).

Mlọ ọgwụ

Pdị P na-amalite ime ọkara ọkara mgbe a gbasịrị, ọnụ - awa nke 2-4. Ogologo oge ruru 8 awa.

Cdị C na-arụ ọrụ mgbe awa 1-2 gachara, ọnụ ọgụgụ kacha elu pụtara n'agbata 6 na 12. Mmetụta ahụ na-ejedebe n'ụbọchị.

M na-amalite ịrụ ọrụ na ọkara otu awa, ọnụ ọgụgụ kasị elu bụ 4-12, ihe a na-akwụsị na awa 24.

Site na insulinase n'ime akụrụ na imeju mebiri ya. Ọ bụ ya mere akụrụ. Naanị soghere incut dị iche iche ka akwadoro ka ha jiri aka ha.

• Bothdị shuga abụọ ahụ
• Ọria mamiri di ime-ime
• Ọrịa
• Igwu ogwu enerieen̄ ogwu enerieen̄ ya.

Ntụziaka maka ojiji (usoro na usoro onunu ogwu)

Routezọ isi nchịkwa bụ ntụtụ dị n'okpuru ala. A na-ahọrọ usoro onyonyo otu otu dabere na ọgbụgba ama yana mkpa anụ ahụ. Ebe a na-agbanye ya bụ ihe mgbochi, oghere, afọ, ubu. Shouldkwesịrị ịgbanwe saịtị ntụtụ gị oge niile.

Nkezi ubochi ubochi bu 0.5-1 IU / n'arọ.

A na-eji "Rosinsulin R" mee ihe ọkara ọkara tupu nri. Onu ogugu doje bu nke dibia bekee deputaro.

Nsonaazụ

• Mmeghachi omume nfụkasị nke mpaghara na sistemụ,
• Hypoglycemia,
• Ike gwụrụ ruo mgbe ọ na-ehi ụra,
• Mbelata BP
• Hyperglycemia na ọrịa shuga acidosis,
• Mmụba nke otu ụzọ n'ụzọ mgbochi ọgwụ mgbochi, sochiri mmụba nke glycemia,
• Ahụhụ anya
• Ihe a na-ahụ anya gbasara insulin nke mmadụ na insulin.
• Hyperemia,
• Lipodystrophy,
• Uwe.

Dodoụbiga ya ókè

Ikekwe mmepe nke hypoglycemia. Ihe omuma ya: agu, pallor, nsogbu iveria na anoko, nkea, ugburu na ndi ozo. Enwere ike wepu ụdị ọkụ ahụ site na iri nri dị ụtọ (swiiti, otu shuga, mmanụ a honeyụ). N'ọdịdị dị nfe na nke siri ike, a ga-achọ ọgwụ ntụtụ nke glucagon ma ọ bụ usoro dextrose, mgbe - nri nwere carbohydrates. Gbalịa ịgakwuru dọkịta maka ịgbanwe ọgwụ ya.

Tụnyere ihe analogues

Rosinsulin nwere ọtụtụ ọgwụ yiri ya, nke ọ bara uru ịmata onwe gị maka iji atụnyere akụ.

Novomiks. Insulin aspart, usoro abuo. Nke Novo Nordisk mepụtara na Denmark. Ọnụahịa - ruru 1500 rubles. maka mbukota. Nsonaazụ nke oge ọkara, dị oke ọsọ ma dị irè. Anabataghị ọgwụ a maka ụmụaka na-erubeghị afọ isii, ma ejiri ya kpachara anya mee n'oge ịtụrụ ime na agadi. A na-ahụkarị mmeghachi omume nfụkasị ahụ na ntụtụ.

"Insuman." Insulin mmadu, umu ihe ato. Ọ na-efu site na 1100 rubles. Onye na - emepụta ihe - "Sanofi Aventis", France. A na-eji ya maka ọgwụgwọ nke ma okenye ma ụmụaka. Ọ na-ebutekarị nsonaazụ. Ezigbo onye otu.

"Protafan." Ọzọkwa insulin nke mmadụ bụ ụdị eji agbanye agbụrụ. Dị ọnụ ala karịa - 800 rubles. maka katọn, ihe ngwọta - 400 rubles. Nke Novo Nordisk nke Denmark rụpụtara. A na-elekọta ya naanị subcutaneously, a na-eji ya agwọ ndị ọrịa ọgbọ ọ bụla. O kwere omume dịịrị ụmụ nwanyị dị ime na ndị na-actụ nwa. Dika onu ahia ma di onu.

"Biosulin." Insulin insulin. Emeputa - Onye na-ere ọgwụ, Russia. Ọnụ ego ahụ ruru 900 rubles. (katrized). Ọ bụ ihe dị mkpirikpi oge. Nwere ike iji na-emeso ndị ọrịa nke afọ.

Humulin. Ọ bụ insulin na-agbanye agbụrụ. Ọnụahịa - site na 500 rubles. n'ihi na karama, katrized dị okpukpu abụọ karịa ọnụ. Companieslọ ọrụ abụọ rụpụtara ọgwụ a ozugbo - Eli Lilly, USA na Bioton, Poland. Ejiri maka ndị nọ n'afọ ndụ ọ bụla, n'ime ụmụ nwanyị dị ime nwere ọrịa shuga. Ekwesịrị iji nlezianya mee ihe maka ndị agadi. Odi na pharmacies na na uru.

Mkpebi ịbufe onye ọrịa site n'otu ụdị ọgwụ gaa na nke ọzọ bụ nke dibịa nọ ya. Amachibidoro ị medicationụ onwe gị ọgwụ!

N'ụzọ bụ isi, ndị ọrịa shuga nwere ahụike na ọgwụ a nwere echiche dị mma. Uzo eji eme ihe, ima ima otutu ichoro. Mana enwere ndị ndị ụdị ọgwụgwọ a adabaghịrị.

Galina: “M bi na Yekaterinburg, a na-agwọ m ọrịa shuga. N'oge na-adịbeghị anya, ana m enweta Rosinsulin maka abamuru. Ọgwụ ahụ na-amasị m, ọ na-adịkwa irè. M na-etinye mkpụmkpụ na ọkara, ihe niile dabara. Mgbe m chọpụtara na nke a bụ ọgwụ ụlọ, o juru m anya. Àgwà a apụtaghị ìhè site na mba ọzọ ”.

Victor: “Protafan lekọtara m. Dọkịta dụrụ obere ọgwụ Russia mebere ọnụ, Rosinsulin. Anọwo m na-eji ya kemgbe ọtụtụ ọnwa ugbu a, enwere m obi ụtọ n'ihe niile. Nchịkwa shuga, enweghị mmetụta ọ bụla, anaghị akpata hypoglycemia. N'oge na-adịbeghị anya, amalitere m inweta uru, nke na-atọ m ụtọ. ”

Vladimir: “Ejiri“ Humalog ”na“ Humulin NPH. ” N'oge ụfọdụ, Rosinsulin nọchiri ha maka uru. M na-eji mkpụmkpụ mkpụmkpụ. Ka m gwa gị eziokwu, ahụghị m ọdịiche ọ bụla pụrụ iche na ọgwụ ndị ị nweburu. Sugar dị mma, enweghị hypoglycemia. Ọdịdị nyocha ahụ gbalitere. Ya mere ana m enye ndụmọdụ ọgwụ a, atụla ụjọ na ọ bụ Russian - akụrụngwa na akụrụngwa, dị ka dọkịta m si kwuo, ndị mba ọzọ, ihe niile bụ site n'ụkpụrụ. Mmetụta ahụ ka mma ọbụna. ”

Larisa: “Dọkịta ahụ kwagara Rosinsulin. Ejiri ya ruo ọnwa ole ma ole, mana nwalee nwale ahụ kara njọ. Ọbụna nri ahụ enyereghị aka. Aghaghị m ịgbanwe n'ụzọ ọzọ, ọ bụghị maka uru, kama maka ego m. Ọ bụ ihe ihere, maka na ọgwụ a na-akwụ ụgwọ ma dịkwa mma. "

Anastasia: “Aha onye nwere oria shuga. Ha nyere Rosinsulin mmetụta dị ka ọgwụgwọ. Short iji Actrapid. Anụrụ m site n'aka ndị ọzọ na ọ na-enyere aka nke ọma, mana n'ụlọ achọtabeghị mgbanwe mgbanwe na steeti. Achọrọ m ịrịọ dọkịta ka ọ gaa na ọgwụ ọzọ, n'ihi na n'oge na-adịbeghị anya, enwere mwakpo hypoglycemia. Ma eleghị anya, ọ dabaraghị m, amaghị m. ”