Ntuziaka maka ọgwụ ọgwụ Telsartan na nyocha banyere ya

Ihe Niile banyere Ọrịa shuga »Otu esi eji Telsartan 40?

Onu ogugu ogwu nke wedata obara mgbali elu ma dowe ya n’ahu odi mma gụnyere Telsartan 40 mg. Uru ọghọm dị na ọgwụ: ị were mbadamba mkpụrụ ọgwụ 1 kwa ụbọchị, ogologo oge mmetụta antihypertensive, enweghị mmetụta ọ bụla na ọnụego obi. Ndị na - egosi ọnya ọbara systolic na diastolic dị ka o kwere mee belata ka ọnwa naanị ị ofụ ọgwụ ahụ.

• 8.10 site na akwara na ọnya biliary
• 8.11 Ahụhụ
• 8.12 Mmetụta ikike ịchịkwa usoro

Weputara udi ya na ihe mebere ya

Ọgwụ bụ mbadamba oval na-acha ọcha na-enweghị shei, convex n'akụkụ abụọ ya. N'ime akụkụ dị elu na nke ọ bụla n'ime ha, enwere ihe ize ndụ maka ịdị mma nke mmebi yana leta "T", "L", na akụkụ ala - ọnụ ọgụgụ "40". N'ime, ị nwere ike ịhụ akwa abụọ: otu bụ pinkish na agba nke ike dị iche iche, nke ọzọ fọrọ nke nta ka ọ bụrụ ọcha, mgbe ụfọdụ enwere obere nsị.

Na mbadamba 1 nke ọgwụ ejikọtara ọnụ - 40 mg nke isi ihe na-arụ ọrụ nke telmisartan na 12.5 mg nke hydrochlorothiazide diuretic.

A na-ejikwa ihe enyemaka:

• mannitol
• lactose (mmiri ara ehi)
• povidone
• meglumine
• stereta magnesium,
• sodium hydroxide
• polysorbate 80,
• iteghete E172.

Na mbadamba 1 nke ọgwụ ejikọtara ọnụ - 40 mg nke isi ihe na-arụ ọrụ nke telmisartan na 12.5 mg nke hydrochlorothiazide diuretic.

Mbadamba 6, 7 ma ọ bụ 10 PC. etinye ya na blisters nke mebere aluminom foil na ihe nkiri polymer. Enyere ya na igbe kaadi 2, 3 ma ọ bụ 4 blisters.

Omume ọgwụ

Ọgwụ a na-arụpụta ọgwụ ọgwụgwọ abụọ: hypotensive na diuretic. Ebe ọ bụ na usoro kemịkal nke ihe dị oke mkpa nke ọgwụ ahụ si yie nke ụdị angiotensin nke 2, telmisartan na-ewepụta ọgwụ a site na njikọta ndị na-anabata arịa arịa ọbara na-egbochi ihe ọ na-eme ogologo oge.

N'otu oge ahụ, amachibidoro mmepụta aldosterone n'efu, nke na-ewepu potassium n'ahụ ahụ ma na-ejigide sodium, nke na-enye aka na mmụba na olu vaskụla. N'otu oge ahụ, a naghị ebelata ọrụ nke renin, enzyme nke na-achịkwa ọbara mgbali. N'ihi ya, mmụba nke ọbara mgbali ahụ na-akwụsị, mbelata nke ukwuu ya na-ewere ọnọdụ.

Mgbe awa 1.5-2 gasịrị ị takingụ ọgwụ ahụ, hydrochlorothiazide na-amalite ịrụ ọrụ ya. Oge ọrụ nke ọnya ahụ dị site na awa 6 ruo awa iri na abụọ. N'otu oge ahụ, olu nke ikesa ọbara na-ebelata, mmepụta nke aldosterone na-abawanye, ọrụ ịmaliteghachi.

Ihe jikọtara ọnụ nke telmisartan na diuretic na-arụpụta ihe akpọrọ antihypertensive mmetụta karịa mmetụta na arịa nke ọ bụla n'otu n'otu. N'oge ọgwụgwọ ọgwụ ahụ, a na-ebelata ngosipụta nke myocardial hypertrophy, a na-ebelata ọnwụ, karịsịa na ndị agadi agadi nwere nnukwu ọrịa obi.

N'oge ọgwụgwọ ọgwụ ahụ, a na-ebelata ngosipụta nke myocardial hypertrophy.

Nchikota nke telmisartan na hydrochlorothiazide anaghị agbanwe ọgwụ ọgwụ nke ihe ndị ahụ. Ha ngụkọta bioavailability bụ 40-60%. Ngwaọrụ nọ n'ọrụ nke ọgwụ ahụ na-agbadakwa ngwa ngwa. Mkpokọta kachasị nke telmisartan na-abanye na plasma ọbara mgbe awa 1-5,5 dịkarịsịrị ala ugboro abụọ n'ime ụmụ nwoke. Ọkpụkpụ metabolism na-eme na imeju, a na-apụtakarị ihe a na feces. A na - ewepụ Hydrochlorothiazide n'ahụ ihe fọrọ nke nta ka ọ bụrụ na mmamịrị agbanwebeghị.

Ihe ngosi maka ojiji

• na usoro ọgwụgwọ ọbara mgbali elu na nke sekọndrị, mgbe ọgwụgwọ ya na telmisartan ma ọ bụ hydrochlorothiazide naanị anaghị enye nsonaazụ achọrọ,
• iji gbochie nsogbu ọrịa ọrịa siri ike na ndị okenye karịa afọ iri ise na ise-60,
• iji gbochie nsogbu ndị ọrịa nwere ụdị shuga II (na-abụghị insulin) mebiri akụkụ ahụ nke ọrịa na-akpata.

Ihe ngbanwe

Ihe kpatara igbochi ọgwụgwọ na Telsartan:

• hypersensitivity na ike n'ọrụ ọgwụ,
• ọrịa siri ike akụrụ
• na-ewere Aliskiren na ndị ọrịa nwere ọrịa gbasara akụrụ, ọrịa shuga,
• gbujuru imeju afọ,
• bile du mgbochi,
• ụkọ lactase, nnagide nri nke lactose,
• hypercalcemia,
• hypokalemia
• ime na lactation
• ụmụaka na-erubeghị afọ 18.

Ekwesịrị ịkpachara anya ma ọ bụrụ na achọpụtara ọrịa ndị a ma ọ bụ ọnọdụ pathologies na ndị ọrịa:

• mbelata n'ọbara,
• stenosis nke akwara gbasara akwara, valvụ obi,
• oke obi ike
• ụkwara ume ọkụ,
• oria shuga
• gout
• adrenal cortical adenoma,
• mmechi mmechi
• lupus erythematosus.

Uzo esi aga na Telsartan 40

Usoro ọgwụgwọ: nchịkwa ọnụ kwa ụbọchị tupu nri ma ọ bụ mgbe nri gasịrị, mbadamba 1, nke a ga-eji obere mmiri washedacha. Ọgwụ kachasị kwa ụbọchị maka ụdị nsogbu ọbara mgbali elu ruru 160 mg. Ekwesịrị iburu ya n'uche: Mmetụta ọgwụgwọ kachasị mma anaghị eme ozugbo, mana mgbe ọnwa 1-2 gachara iji ọgwụ ahụ.

Usoro ọgwụgwọ: nchịkwa ọnụ kwa ụbọchị tupu nri ma ọ bụ mgbe nri gasịrị, mbadamba 1, nke a ga-eji obere mmiri washedacha.

A na-enyekarị ndị ọrịa nwere ọrịa a iwu ka ha gbochie nsogbu n’obi, akụrụ, na anya. Maka ọtụtụ ndị ọrịa mamịrị na-arịa ọbara mgbali elu, egosipụtara ngwakọta nke Telsartan na Amlodipine. N'ọnọdụ ụfọdụ, mkpo uric acid n'ime ọbara na-ebili, gout na-akawanye njọ. Ọ nwere ike ịdị mkpa ịhazigharị ọgwụ nke hypoglycemic ọgwụ.

Nsonaazụ ọzọ nke Telsartan 40

Ndekọ ọnụ ọgụgụ nke mmeghachi omume na-adịghị mma maka ọgwụ a yana telmisartan nke na-enweghị hydrochlorothiazide bụ otu ihe. Ugboro nke ọtụtụ mmetụta dị iche iche, dịka ọmụmaatụ, nsogbu nke trophism anụ ahụ, metabolism (hypokalemia, hyponatremia, hyperuricemia), adịghị emetụta usoro onodu ogwu, okike na afọ nke ndị ọrịa.

Ọgwụ na-adịghị ahụkebe nwere ike ibute:

• ọnụ kpọrọ nkụ
• dyspepsia
• flatulence
• mgbu afọ
• afọ ntachi
• afọ ọsịsa
• vomiting
• eriri afọ.

Mmeghachi omume ọgwụ a nwere ike ịgụnye:

• mbelata na ọkwa hemoglobin,
• anaemia
• eosinophilia
• thrombocytopenia.

Nsonaazụ mgbe niile bụ ọgbụgba. N’oge na-adịghị anya:

• paresthesia (sensations nke na-akpụ akpụ goosebumps, tingling, na -egbu mgbu),
• ehighi ura ma obu, ura, ura,
• ọhụhụ
• ọnọdụ nchegbu
• ịda mba
• syncope (ike gwụrụ na mberede), na-akụda.

• ịba ụba uric acid, creatinine na plasma ọbara,
• mmụba nke enzyme CPK (creatine phosphokinase),
• nnukwu akwara ọdịda
• urinary tract na-efe efe, gụnyere ahu otutu.

Mmeghachi omume ọjọọ:

• obi mgbu
• mkpụkpu ume
• oria-di ka oria, sinusitis, pharyngitis, bronchitis,
• oyi baa, edere nke edere.

• erythema (oke-acha ọbara ọbara nke anụ ahụ),
• ọzịza
• ihe nwu
• itching
• ịba ụba,
• urticaria
• ọrịa akpịrị
• amu amu
• angioedema (nke a na-anaghị ahụkebe).

Telsartan adịghị emetụta ọrụ nke akụkụ akụkụ ahụ.

• oria hyia, orthostatic hypotension,
• bradi, tachycardia.

Mmeghachi omume ndị na-esote usoro musculoskeletal nwere ike:

• nkpatu, ihe mgbu na akwara, akwara, nkwonkwo,
• ogwe aka, otutu mgbe na ukwu aka,
• lumbalgia (nnukwu ihe mgbu na ala ala azụ).

N'okpuru mmetụta nke ọgwụ ahụ n'oge ụfọdụ, enwere ike ịhụ ihe ndị a:

• ọrịa imeju na imeju,
• mụbara ọrụ enzymes nke ahụ mepụtara.

Anaphylactic ujo di obere.

Ebe ọ bụ na ihe ize ndụ nke ụra ụra, enweghị ike ịkwụsị ịlụ dizzness, a na-adụ ọdụ mgbe ị na-anya ụgbọala, na-arụ ọrụ chọrọ nlebara anya kachasị.

Ntụziaka pụrụ iche

Site na ụkọ nke sodium dị na plasma ma ọ bụ olu na-erugharị ọbara ezughị ezu, mmalite nke ọgwụgwọ ọgwụ ahụ nwere ike ibute mgbanye nke ọbara. Ọrịa hypotension na-ebulitekarị ndị ọrịa nwere akwara vaskụla olu, akwara obi na nkụda obi. Mbelata nke nrụgide dị egwu nwere ike ibute ọrịa strok ma ọ bụ infarction myocardial.

Jiri ọgwụ jiri nlezianya na iji stenosis nke mitral ma ọ bụ aortic valve.

N'ime ndị ọrịa mamịrị, ọgụ hypoglycemia ga-ekwe omume. Ọ dị mkpa ịlele ọkwa glucose kwa n'ọbara, mezie ọnụọgụ nke ndị na - ahụ ihe hypoglycemic.

N'ime ndị ọrịa mamịrị, ọgụ hypoglycemia ga-ekwe omume.

Hydrochlorothiazide dị ka akụkụ nke Telsartan nwere ike ime ka ịta ahụhụ nke ogige mmiri ọgwụ na-egbu egbu bụrụ ihe kpatara ọrụ ezumike, yana mekwa ka mmepe nke nnukwu myopia, angle-mechie glaucoma.

Ogologo oge ị ofụ ọgwụ ahụ na-akpata hyperkalemia. Ọ nwere ike ịdị mkpa ileba anya n’ihe dị n’ime electrolytes n’ime plasma ọbara.

Sharpkwụsị ọgwụ dị nkọ adịghị eduga nzụlite nke ndọrọ ego.

Site na hyperaldosteronism bụ isi, ọgwụgwọ ọgwụgwọ nke Telsartan fọrọ nke nta ka ọ ghara.

A na - egbochi ọgwụ ọgwụ ọjọọ n'oge a na - eme ya na inye ya ara.

Emeghị ọgwụ a iji mee ihe maka ndị ọrịa na-erubeghị afọ 18.

Na enweghi ọrịa dị egwu, ọ nweghị mkpa maka nhazi ndozi.

Ndozi usoro onunu ogwu achoghi ka ndi ọrịa nwere nsogbu gbasara akwara ha buru ibu, ha gunyere na-anagide usoro ọgwụgwọ nke akwara.

Dabere na nsonaazụ nke ọtụtụ ọmụmụ na ndị ọrịa nwere ọrịa imeju na-arụ ọrụ dị nro ma na-agafeghị oke, kwa ụbọchị ọgwụ ahụ ekwesịghị gafere 40 mg.

Dabere na nsonaazụ nke ọtụtụ ọmụmụ na ndị ọrịa nwere ọrịa imeju na-arụ ọrụ dị nro ma na-agafeghị oke, kwa ụbọchị ọgwụ ahụ ekwesịghị gafere 40 mg.

Mmekọrịta na ọgwụ ndị ọzọ

N'iji oge ọzọ na ọgwụ ndị ọzọ na - ebelata ọbara mgbali, ọgwụ a na - eme ka ọgwụgwọ ha dịkwuo mma.

Mgbe ị na-ewere Telsartan na Digoxin, itinye uche nke glycoside gbasara obi na-abawanye nke ukwuu, yabụ, ọ dị mkpa ileba anya na ọkwa ọbara ya.

Iji zere hyperkalemia, ekwesighi ijikọ ọgwụ ahụ na ndị nwere potassium.

Nnyocha nke lithium n'ọbara ka ị na-a usingụ ọgwụ ndị nwere nchịkọta nke alkali a, n'ihi telmisartan na-eme ka ha egbu egbu egbu.

Glucocorticosteroids, Aspirin na ọgwụ mgbochi mkpali na - abụghị ọgwụ steroidal na - ebelata mmetụta antihypertensive nke ọgwụ ahụ.

NSAIDs na telmisartan nwere ike imebi ọrụ akụrụ.

Mgbe ị na-a withụ ọgwụ, ịkwesighi ị drinkụ mmanya ụdị ọ bụla.

Enwere ike dochie Telsartan na ọgwụ ndị na-esonụ nwere mmetụta yiri ya:

Nyocha na Telsartan 40

Maria, dị afọ 47, Vologda

Ọgwụ dị ukwuu ma yie ihe kachasị mma n'ọtụtụ ọgwụgwọ maka ọrịa vaskụla. Ọ bụ ihe ijuanya na a na-emepụta ọgwụ dị otú ahụ na India, ọ bụghị na Germany ma ọ bụ Switzerland. Mmetụta ọghọm dị obere. Mgbe ụfọdụ, imeju na-enye m nsogbu, mana ọ na-ewute m ogologo oge mgbe m na-ewerebeghị Telsartan.

Vyacheslav, 58 afọ, Smolensk

Enwere m ogologo akụkọ banyere ọbara mgbali elu. Gụnyere nnukwu akwara ọdịda. Kedu ụdị ọgwụgwọ emebeghị nke ọtụtụ afọ ọgwụgwọ! Ma n'oge ụfọdụ, a ga-agbanwe ha, maka na anụ ahụ ga-eme ya eme, ma kwụsịkwa ime ihe dịka ọ dị na mbụ. Ana m ewere Telsartan n'oge na-adịbeghị anya. Ntụziaka maka ya na-enye ndepụta dị ukwuu nke nsonaazụ ọ bụla, mana ọ dịghị nke ọ bụla n'ime ha bilitere. Ezigbo ọgwụ nke na-ejide ike. Eziokwu dị obere.

Irina, 52 afọ, Yekaterinburg

N’oge izizi, onye na-agwọ ọrịa ahụ kwuru na a ga-ewere Amlodipine, mana ka otu izu gasịrị, ụkwụ ya malitere ịza. Dọkịta ji Enap dochie ya - n’oge na-adịghị anya ụkwara bidoro kpagbu m. Ekwesịrị m ịgbanwere na Telsartan, mana ọ bịara bụrụ na enwere m ndidi ọ bụla n'otu n'otu. Enwere ọgbụgbọ, mgbe ahụ, ihe ọkụ anụ ahụ pụtara. Agakwara m ụlọ ọgwụ ọzọ. Ma ọ bụ naanị mgbe onye na-ahụ maka ọgwụgwọ ahụ nyere iwu ka ọ bụrụ Concor ka ihe niile dakwasịrị. Enweghị m nsogbu na ọgwụ ndị a. Yabụ na ọ dị ezigbo mkpa na dọkịta ga-ahọrọ ọgwụ ziri ezi maka gị.

Ihe omuma banyere ogwu

Omume nke ọgwụ ahụ gụnyere ọ bụghị naanị iweda ọbara mgbali elu, kamakwa dịka mbenata ibu ahụ na obi, nchedo akụkụ ahụ (retina, vaskụla endothelium, myocardium, ụbụrụ, akụrụ), mgbochi nke nsogbu (nkụchi obi, ọnya obi), karịsịa na ọnụnọ nke ihe ndị ọzọ dị ize ndụ (ịmụba ọbara viscosity, ọrịa shuga mellitus).

Telsartan na-ebelata insulin iguzogide, na-abawanye uru glucose, na-agbazi dyslipidemia (belata ọnụ ọgụgụ nke "LDL" na-emerụ ahụ ma na-abawanye HDL "bara uru").

Ndị na-ahụ maka ọgwụ, INN, akporo

Telsartan bụ onye na - anabata angiotensin-II receptor blocker (AT1). Telsartan N - maka ọgwụ ọgwụ, jikọtara ngọngọ nke ndị na-anabata angiotensin-II (AT1) na isi ihe na-arụ ọrụ na mmetụta antidiuretic nke hydrochlorothiazide. Site na usoro nke kemịkalụ, ọ bụ nke biphenyl netetrazole ogige. Ọ bụ ọgwụ na-arụ ọrụ. Onye na-asọ mpi nke na-arachi ndị na-anabata ya n'echeghị eche.

Nsonaazụ nke ndị nnabata antiotensin II

INN: Telmisartan / Telmisartan. Ejiri cardiology n'ọgụ megide mmụba systolic na nrụgide diastolic, nkụda obi. A na-eji Telsartan N mee ihe maka arụ ọrụ nke ọgwụ monotherapy na ọgwụ ndị ọzọ.

Ofdị ntọhapụ na ọnụahịa maka ọgwụ ahụ, nkezi na Russia

A na-emepụta ọgwụ ahụ n'ụdị mbadamba, na usoro abụọ - 40 na 80 mg. N’ime kaadiboodu 3 blister nke mbadamba 10. Mbadamba ahụ nwere ọdịdị oval nke nwere ogologo oge, convex n'akụkụ abụọ, na-enweghị shei, snow-white na agba, nwere akara dị n'etiti etiti ahụ, n'akụkụ nke abụọ nwere ihe ngosi abụọ - "T na L", egosiri usoro ọnụọgụ ahụ n'akụkụ nke ọzọ.

Tebụl dị n'okpuru na-egosi ọnụahịa dị na rubles maka ọgwụ ọjọọ:

Tebụl na-egosi ihe ndị dị mkpa ọgwụ ahụ:

Pharmacodynamics na pharmacokinetics

Telsartan bụ ụdị nhọrọ angiotensin-II receptor inhibitor na-ahọrọ. Ndị na-anabata ihe ndị a dị n'ọtụtụ anụ ahụ, ọkachasị na akwara ndị dị nro, arịa myocardium, cortical nke gren adrenal, ngụgụ, na akụkụ ụfọdụ nke ụbụrụ. Angiotensin-II bụ ihe kachasị nwee mmetụta peptide nke sistemụ renin-angiotensin-aldosterone (RAAS).

Site na ndị nabatara ụdị a, mmetụta ndị a na-achọpụta na n’onwe ha ma ọ bụ n’enweghi aka na-atụnye ụsọ ọsọ, mana ọ na-abụkarị mkpụmkpụ nke ọbara mgbali elu. Omume nke Telsartan bu n'uche na mbelata ha, ya bụ, a na-egbochi ya ma ọ bụ gbochie ya:

• mmụba na ngụkọta ọnọdụ ọgụ nke akwara dị iche iche,
• vasoconstriction nke arịa ọbara nke glomeruli nke akụrụ na mmụba na nrụgide hydraulic n'ime ha.
• njigide nke anụ ahụ: ịba ụba nke sodium na mmiri na tubules proximal, mmepụta nke aldosterone,
• mwepụta nke homonụ antidiuretic, endothelin-1, renin,
• mmegharị nke usoro ọmịiko na adrenal na mwepụta nke catecholamines n'ihi ịbanye na mgbochi ụbụrụ ọbara,

Na mgbakwunye na RAAS systemic, enwere usoro anụ ahụ (mpaghara) RAA dị iche iche na anụ ahụ na-emetụta. Ntinye ha na - akpata mmetụta nke ogologo oge nke angiotensin, nke na - eduga n'ịba ụba nke endothelium na uru ahụ nke akwara ọbara, cardiomyocyte hypertrophy, mmezi myocardial, myofibrosis, mmebi vaskụla atherosclerotic, nephropathy, na mmebi akụkụ ahụ.

Otu njiri mara nke Telsartan bụ na ọ na - ejikọ ya naanị n'ụdị nke ndị na - anabata angiotensin-II nke mbụ ruo ogologo oge wee wepu mmetụta ọjọọ nke angiotensin kpamkpam, "enyeghị" ya ka ọ bụrụ ndị na - anabata ya.

Omume ahụ dị site na awa 24 ruo 48. Mbelata ọbara mgbali na-apụta nke ọma, nke nta nke nta ruo ọtụtụ awa. Tụnyere otu ACE inhibitors, nke e lere anya na otu n'ime otu ọgwụ kachasị mma maka antihypertensive, usoro ndị a bụ uru doro anya nke ọgwụ ahụ:

• mgbochi zuru oke nke mmetụta ọjọọ nke angiotensin (anaghị egbochi ndị mgbochi ACE kpamkpam),
• n'ịghọta mmetụta dị mma nke angiotensin site na ndị na-anabata ụdị AT2 (ndị na-egbochi ACE, na Kama nke ahụ, belata),
• n'ihi na nke ọ nweghị mmetụta ọ bụla na bradykinin na, n'ihi nke a, mmeghachi omume ọjọọ na-esonyere ya (ụkwara, angioedema, utotoxic, ịba ụba prostacyclin synthesis),
• organoprotection.

A na-amụ ndị na-anabata ụdị nke abụọ nke ọma, mana ndị sayensị nwere ike igosipụta na ha nwere ọtụtụ n'ime oge ẹmbrayonụ, nke nwere ike igosipụta mmetụta ha na uto sel na ito eto. Mgbe nke a gasịrị, ọnụ ọgụgụ ha na-ebelata. Omume a site na ndị nnabata ndị a bụ ihe megidere ọrụ nke ndị na-anabata ndị mbụ. Mmetụta dị mma site na ndị na-anabata AT2 bụ ndị a:

• mmezi anụ ahụ na ọkwa cellular,
• vasodilation, ịba ụba njikọ nke NO-factor,
• ihe mgbochi nke mkpụrụ ndụ, ịmụba,
• mgbochi nke ọbara mgbali.

Telsartan H nwere mmetụta antihypertensive dị ike karị, nke nwere hydrochlorothiazide - ọnya loop nke na-ebelata ndọghachi azụ nke sodium ion na mmiri site na akụrụ, na-enye mmetụta antidiuretic. Ọ na - enyekwa ohere iji: kama ọtụtụ mbadamba, ọ zuru ezu iji ya otu ugboro kwa awa 24, nke ga - eweta nsonaazụ jikọtara ọnụ.

Site n'iji ya eme ihe, ọgwụgwọ ọgwụgwọ nke telmisartan na-aputa ihe dị ka izu asaa ruo asaa. Ọ na -ewebelata nrụgide systolic na diastolic. Enweghị ọrịa nkwụghachi: mgbe ị kwụsịrị ị theụ ọgwụ ahụ, nrụgide ahụ na-alaghachi na ọnụ ọgụgụ dị elu ọzọ ruo ọtụtụ ụbọchị, enweghị jumps dị nkọ mgbe ị kwụsịrị.

Mgbe ewere kwa os, a na-abanyekarị n'ọbara kachasị mgbe awa 1-2 gachara. Bioavailability bụ 60%, na-abanye ngwa ngwa. Enwere ike ị drugụ ọgwụ ahụ n'oge ọ bụla, n'agbanyeghị nri nri. 98.6% ma ọ bụ karịa jikọtara na protein ndị dị na plasma, na-ejikọkwa akwara ndị ọzọ (olu nkesa ihe dị ka 510 l).

Ntinye uche nke ọbara ụmụ nwanyị karịrị nke ụmụ nwoke, nke a anaghị emetụta arụmọrụ. Ihe dị ka 98% nke telmisartan na-apụta site na sistemụ biliary, obere - yana mmamịrị. A na-agwakọta ya site na conjugation, na-eme ka e guzobe acetylglucoronide n'ụdị arụghị ọrụ. Mkpokọta zuru oke karịa 1499 ml / min. Iwepu ọkara ndụ dị ihe karịrị awa iri na itoolu. Hydrochlorothiazide adịghị metabolized ma wepu ya n'ụdị efu site na mmamịrị.

Pharmacokinetics adịghị agbanwe dabere na nwoke na nwanyị. N'ime ndị ọrịa nwere ọrụ ọfụma nke usoro ịtụ ụjọ, itinye uche n'ọbara dị ọtụtụ ugboro karịa ka ọ dị na mbụ, yana nkwonkwo akwara dị ala, na-agbadata, belata, n'agbanyeghị eziokwu ahụ nwere ihe jikọrọ ya na protein protein. N'ihe banyere ọrụ ịba ọcha n'anya, bioavailability mụbara 98%.

Ihe ngosi na contraindications

Isi ihe na-egosi maka ojiji nke Telsartan:

• ọbara mgbali elu
• mgbochi nke obi na ọrịa vaskụla,
• Mbelata mmebi nke CVD na ndị ọrịa nwere ụdị ọrịa shuga 2 nke mebiri emebi na akụkụ ahụ,
• oké vaskụla atherosclerosis.

• ọgwụ ndị mejupụtara ọgwụ ahụ,
• Oge nke atọ na nke atọ nke afọ ime, inye nwa ara,
• obere afọ
• ihe mgbochi nke biliary sisitemu,
• nnukwu mbibi nke imeju,
• hypokalemia na hyperka hyperka,
• gout
• n'otu oge eji Aliskiren na-arịa ọrịa shuga.

N'ihi ezughi ezu nyocha, ekwesighi inye ụmụaka ọgwụ na-erubeghị afọ 18 ọgwụ a. Amachibidoro ị toụ ọgwụ ahụ n'oge afọ ime, ọkachasị na oge nke abụọ na nke atọ, ebe ọgwụ nwere mmetụta fetotoxic dị elu: mbelata ọrụ nke usoro excretory, mbelata nke mkpochapu, na oligohydramnios.

N'ime ụmụ amụrụ ọhụrụ, enwere: ihe na-aba ụba nke potassium, mbelata nke ume, oke nke usoro ahụ. Ekwesịrị ịkwụsị ma were ọgwụ ọgwụ ọzọ dochie Sartans. Jide n'aka na ị ga-elezi anya nwa ebu n’afọ na nne ya.

Ntụziaka maka ojiji

A na-a drugụ ọgwụ ahụ otu ugboro kwa awa iri abụọ na anọ n'otu oge, n'agbanyeghị nri ahụ. Na-a plentyụ ọtụtụ mmiri mmiri. Dabere na ntuziaka maka ojiji nke Telsartan, dose mbụ bụ 20 mg, mgbe ahụ enwere ike ịbawanye dose ahụ. Usoro ọgwụgwọ nke 40 mg na-adị irè n'ịgwọ ọrịa. N'ime ndị ọrịa "nọgidesiri ike", ịnwere ike ịbawanye usoro onunu ogwu ka 80 mg kwa ụbọchị, mana ọ bụghị karịa. Nke a na usoro onunu ogwu kacha.

Dịka ihe ọzọ maka ọdịda nke monotherapy, a na-eji njikọta nke angiotensin receptor blockers na diuretic, ọgwụ Telsartan N.

A naghị atụ aro ka ijikọta Telsartan na nhazi nke potassium, ndị na-egbochi ACE, saluretics-potassium, NSAIDs, Heparin, immunosuppressants - n'ihi na nke a nwere ike ịkpasu oke mmụba na ion potassium na ahụ. A naghị atụ aro iji ihe oriri na lithium eme ihe, n'ihi na nke a nwere ike ibute nsị ya oke.

Ndị ọrịa hypertensive na-echekarị ma enwere ike ịnara Telsartan na Diuver n'otu oge. Nnyocha e mere egosiwo na ojiji nke telmisartan na torasemide, nke bụ isi ihe na-arụ ọrụ nke ọgwụ ndị a, na-eduga n'ịbelata ọbara mgbali elu.

Jiri ngwakọta a jiri nlezianya mee ihe, ebe ọ bụ na ị fluidụ mmiri gabigara ókè nwere ike iduga hypotension. Tupu ị drugụ ọgwụ ọ bụla, yana karịa nke otu ha, ị kwesịrị ịkpọtụrụ dọkịta gị.

Effects nwere ike inwe mmetụta ọjọọ yana ị andụbiga mmanya ókè

Dodoụbiga mmanya ókè nwere ike iyi ihe ndị a:

• hypotension
• tachycardia
• ọrịa dyspeptik
• gbasara akwara.

Ogwu ahu nwere otutu ihe omuma ya, nke adighi adighi ike:

• mmekọrịta,
• arrhythmia, tachycardia,
• anya ntughari
• vertigo
• parasthesia
• ihe dyspeptik.

Ndị bụ isi n'ọnọdụ ọgwụ Telsartan:

• Mikardis.
• Telzap
• Telmista.
• Telpres.
• Ochichi.
• Tanidol.
• Ndị a.
• Hipotel.

Ọdịiche kachasị mkpa dị n'etiti ọgwụ ndị a bụ ọnụahịa, mba si malite dịkwa iche, nke na-emetụta ogo nhicha nke mmiri ọgwụ. Njirimara nke ọgwụ ndị a bụ otu ihe. Mana ụdị analogues nke kachasị dị irè bụ Mikardis, Praitor na Telpres.

Nyocha nke ndị dọkịta na ndị ọrịa

Na mkpokọta, ma ndị ọkachamara na ndị ọrịa nyere ọtụtụ nyocha dị mma banyere ọgwụ, lee ụfọdụ n'ime ha:

Alexander Dmitrievich, ọkachamara n'ọrịa kadio: “Ọgwụ a nwere ikike mbelata nke ọma. Mmetụta ya na-anọ ogologo oge.

Otu njirimara na uru doro anya bụ nbibi ya na - egbochi mmerụ ahụ nke angiotensin ma na - enwe ọfụma. Zuru iwe otu mbadamba ụbọchị. O dikwa ezigbo mfe ịhọrọ ma dozie dose ahụ. Ọgwụ ọjọọ nke ọgbọ ọhụrụ nwere obere ogo ọghọm ya. "

Dabere na data a ma ama banyere ọgwụ ahụ, anyị nwere ike iji obi ike kwuo na taa ọ bụ otu n'ime ọgwụ antihypertensive kachasị dị irè. Jiri nwayọ wepu ihe na-adịghị mma ma na-enwe ezi mmetụta na akụrụngwa obi na ahụ niile.

International Nonproprietary Aha

INN ọgwụ - Telmisartan.

Na nhazi ọkwa mba ụwa nke ATX, ọgwụ nwere koodu C09CA07.

Ekwesiri iji Telsartan maka ọtụtụ ọrịa, yana mmụba nke ọbara mgbali.

Mlọ ọgwụ

Mgbe ị na-a theụ ọgwụ ahụ, akụkụ ya dị n’ọrụ na-abanye ngwa ngwa. Bioavailability ruru 50%. Oke ọgwụ nke ọbara na-adị n’ime ụmụ nwoke na ụmụ nwanyị ka enwetara awa 3 mgbe nchịkwa gasịrị. Ọgwụ ahụ na-egbochi protein ndị dị na plasma. Metabolism nke ọgwụ ahụ sitere na ntinye nke glucuronic acid. A na-apụtakarị Metabolites na feces n'ime awa iri abụọ.

Jiri nlezianya

Ọgwụgwọ na telsartan chọrọ ịkpachapụ anya na akwara akwara Stenosis. Na mgbakwunye, ndị ọrịa nwere mitral na aortic valve stenosis n'oge ọgwụgwọ na Telsartan chọrọ nlebara anya pụrụ iche site n'aka ndị ọrụ ahụ ike. Ekwesịrị ilebara hypokalemia na hyponatremia anya pụrụ iche. Ọ ga-ekwe omume iji ngwaahịa a naanị n'okpuru nlekọta ndị dọkịta ma ọ bụrụ na enwere onye ọrịa nwere akụkọ ntughari akụrụ.

Na-arịa ọrịa shuga

Maka ndị ọrịa na-arịa ụdị ọrịa shuga 2, a na-edenye ọgwụ ahụ na mmalite nke 20 mg. N’ọdị n’ihu, enwere ike ịba ụba usoro ọgwụ kwa ụbọchị ruo 40 mg.

Iri nri anaghị emetụta nnabata nke ike ọgwụ a.

Site na usoro mkpụrụ ndụ ihe nketa

Patientsfọdụ ndị ọrịa na-ebute cystitis. N'ọnọdụ ndị a na - adịghị ahụkebe, megide nzụlite nke ọrịa na - efe efe nke afọ, sepsis nwere ike ime.

Patientsfọdụ ndị ọrịa na-ebute cystitis.

N'akuku nke imeju na akụkụ biliary

Ọ dị ụkọ na ọgwụgwọ Telsartan na enwere mmebi nke ọrụ imeju na ọnya biliary.

Ọ dị ụkọ na ọgwụgwọ Telsartan na enwere mmebi nke ọrụ imeju.

Ọ bụrụ na onye ọrịa ahụ nwere hypersensitivity, mmeghachi omume nfụkasị ahụ nwere ike ime, gosipụtara dịka ọnya ọnya na itching, yana edema Quincke.

Jiri n'oge ime na lactation

Usoro ọgwụgwọ nke Telsartan maka ụmụ nwanyị n'afọ atọ ọ bụla dị ime adịghị anabata. A naghị akwado ya ka ọ useụọ ọgwụ maka ara ara.

Usoro ọgwụgwọ nke Telsartan maka ụmụ nwanyị n'afọ atọ ọ bụla dị ime adịghị anabata.

Ngwa maka ọrụ mmeju na-arụ ọrụ

Enweghị ike iji ọgwụ ahụ agwọ ọrịa nke ndị nwere ọrịa imeju, yana mgbochi nke biliary tract na cholestasis.

Enweghị ike iji ọgwụ ahụ agwọ ọrịa nke ndị nwere ọrịa imeju, yana mgbochi nke biliary tract na cholestasis.

Mmanya ndakọrịta

Should ga-ajụ ị takeụ mmanya mgbe ị na-anabata Telsartan.

Should ga-ajụ ị takeụ mmanya mgbe ị na-anabata Telsartan.

Mmechi Telsartan nke nwere ụdị ọgwụgwọ ọgwụgwọ ahụ gụnyere: