Berlition 300: ntuziaka maka ojiji
Injection 25 mg / ml | 1 amam |
ethylenediamine nnu nke alfa lipoic acid | 388 mg |
(nke kwekọrọ na 300 mg nke thioctic (alpha-lipoic) acid) | |
ndị mbụ: propylene glycol, mmiri maka injection |
n'ime ampoules nke agba aja aja nke 12 ml, na igbe kaadiboodu nke 5, 10 ma ọ bụ 20 ampoules.
Mbadamba ụrọ a kpuchiri ekpuchi | Taabụ 1. |
ọgwụ thioctic (alfa lipoic) acid | 300 mg |
ndị mbụ: lactose monohydrate, magnesium stearate, MCC, ssumum croscarmellose, povidone, hydrated silicon dioxide. |
na ngwungwu ngwugwu nke pcs 10., n'ime igbe kaadi nke 3, 6 ma ọ bụ 10 ngwugwu.
Omume ọgwụ
Dị ka coenzyme nke mitochondrial multienzyme ogige, ọ na-esonye na oxarative decarboxylation nke pyruvic acid na alfa-keto acid. Na-enyere aka belata glucose ọbara ma mee ka glycogen nwee umeji, yana imeri nguzogide insulin.
Site na okike nke ndu ogwu ndu, o di nso na vitamin B sonyere na nhazi nke metabolism nke metabolism, megharia cholesterol metabolism, ma melite oru umeji. Ojiji nke trometamol nnu nke thioctic acid (inwe mmeghachi omume na-anọpụ iche) na ngwọta maka nchịkwa iv na-enye ohere iji belata ịdị njọ nke mmeghachi omume ọjọọ.
Mlọ ọgwụ
Mgbe a na -ewere ya ọnụ, ọ na-ewepu ngwa ngwa na ngwangwa ahụ site na eriri afọ (ị withụ nri na-ebelata mmịpụta). Oge iru Cmax - Nkeji 40-60 Bioavailability bụ 30%. O nwere nsonaazụ nke “ụzọ izizi” site na imeju. Guzobe metabolites na - aputa ihe n'ihi nsị oxidation na conjugation n'akụkụ. Olu nke nkesa dị ihe dịka 450 ml / n'arọ. Metabolzọ metabolic bụ ụzọ dị mkpa bụ oxidation na conjugation. Ọ bụ akụrụ na -akpo Thioctic acid na metabolites ya (80-90%). Ndi1/2 - Nkeji 20-50 Mkpokọta plasma Cl - 10-15 ml / min.
Nsonaazụ
Ngwọta nke ntụtụ: oge ụfọdụ mmetụta ịda mbà n'isi na mkpụmkpụ ume (ya na nchịkwa ngwa ngwa). Ọ ga - ekwe omume mmeghachi omume nke Allergic na ntanetị ahụ yana ọdịdị urticaria ma ọ bụ mmetụ ọkụ. N'ọnọdụ ụfọdụ, ahụ mkpọnwụ, diplopia, ọnya ọbara dị n'ahụ na akpụkpọ ahụ mucous.
Mbadamba ụrọ mkpuchi: n'ọnọdụ ụfọdụ, mmeghachi omume nfụkasị anụ ahụ.
Obelata suga shuga enwere ike.
Usoro onunu ogwu na nhazi
Iv. Na polyneuropathies siri ike, 12- 24 ml (300-600 mg nke alpha-lipoic acid) kwa ụbọchị maka izu 2-4. Maka nke a, 1-2 ampoules nke ọgwụ ahụ na-agbari na 250 ml nke physiological 0.9% sodium chloride solution ma na-ejikwa ụzọ isi ihe dị ka 30 nkeji. N'ọdịnihu, ha na-atụgharị na ọgwụgwọ Berlition 300 n'ụdị mbadamba mbadamba 300 kwa ụbọchị.
Maka ọgwụgwọ nke polyneuropathy - 1 tebụl. 1-2 ugboro n'ụbọchị (300-600 mg nke alpha-lipoic acid).
Nchedo nchekwa
N'oge ọgwụgwọ, mmadụ kwesịrị ịhapụ ị beụ ihe ọ alcoụ alcoụ na-egbu egbu (mmanya na ngwaahịa ya na-ebelata ike ọgwụgwọ).
Mgbe ị na-a theụ ọgwụ ahụ, ị kwesịrị ị na-enyocha ọkwa shuga dị n'ọbara mgbe niile (karịchaa na usoro ọgwụgwọ mbụ). N'ọnọdụ ụfọdụ, iji gbochie ihe mgbaàmà hypoglycemia, ọ nwere ike ịdị mkpa iji belata ọgwụ insulin ma ọ bụ onye na-ahụ maka ọgwụ antidiabetic.
Mwepụta wepụtara ya na ihe mejupụtara
A na-amịpụta mkpụrụ n'ụdị mbadamba mkpuchi, mbadamba 30 kwa ngwungwu (3 blisters nke mbadamba 10). Ofdị mgbapụta ndị ọzọ gụnyere capsules gelatin maka iji ya eme ihe, itinye uche maka nkwadebe nke ngwakọ infusion.
Ihe kachasị dị na ya bụ acid thioctic (alpha-lipoic). Otu mbadamba ihe nwere 300 mg nke thioctic acid.
Ihe inyeaka: microcrystalline cellulose, sillololo silikon collolo, lactose monohydrate, sodium croscarmellose, magnesium stearate, povidone.
Ihe ngbanwe
Ihe ndi mmadu na egbochi ndi Berlition.
- hypersensitivity mmeghachi omume ma ọ bụ anabataghị Alfa-lipoic acid ma ọ bụ otu n'ime ihe inyeaka nke ọgwụ ahụ.
- imebi nnabata nke glucose-galactose, galactosemia, ụkọ lactase,
- ime na lactation,
- afọ n'okpuru afọ 18.
Usoro onunu ogwu na nhazi
A na-ewere ọnụ dị ka mkpụrụ osisi Berlition, ọ bụghị nke a gwepịara eghe. A na-a drugụ ọgwụ ahụ otu ugboro n'ụbọchị, n'ụtụtụ, ọkara otu awa tupu nri ụtụtụ.
Ọgwụgwọ dị ogologo. Dọkịta kpebisiri ike ịmata usoro ọgwụgwọ ya iche iche, dabere na ngosipụta na ọnọdụ onye ọrịa ahụ.
Na polyneuropathy na-arịa ọrịa shuga, a na-enye alpha-lipoic acid na usoro nke 600 mg kwa ụbọchị.
Maka ọrịa ọrịa imeju, ịsụ ọgwụ kwa ụbọchị maka ndị okenye sitere na 600 mg ruo 1200 mg.
Ntụziaka pụrụ iche
N'oge ọgwụgwọ na Berlition, ekwesiri iburu n'uche ihe ndị a:
- Na mmalite nke ọgwụgwọ na ndị ọrịa nwere polyneuropathy, mmụba nke paresthesia ga-ekwe omume,
- ndị ọrịa na-arịa ọrịa shuga ka ha na-ewere mbadamba nkume ndị ahụ, na-achọ ka ha na-enyocha ọkwa glucose ọbara mgbe niile.
- ị gaghị a drinkụ mmanya mgbe ị na-elekọta ya,
- Enweghị data na nsonaazụ alpha-lipoic acid n’arị n’arụ nwa na n’ahụ nwata, yabụ, edeghị ọgwụ a n’oge di ime na inye nwa ara.
Mmekọrịta ọgwụ ọjọọ na iji otu oge:
- a na-ebelata ọgwụgwọ ọgwụgwọ nke cisplastine,
- mmetụta nke ọgwụ hypoglycemic na-abawanye,
- Site na ọla, gụnyere magnesium, iron, yana calcium, alpha-lipoic acid na-ejikọ ọnụ na mgbagwoju anya, yabụ, iji nkwadebe nwere ihe ndị a, yana iji ngwaahịa mmiri ara ehi, na-ahapụ naanị awa 6-8 ka ewere Berlition.
Analogues nke ọgwụ (ya na otu ihe arụ ọrụ) gụnyere: Alpha Lipon, Dialipon, Thioctodar, Tiogamma, Espa-Lipon, Thioctacid BV.