Insulin Insuman Bazal GT
Nkwụsịtụ maka nchịkwa okpuru ala nke 100 IU / ml
1 ml nke nkwusioru nwere
ike - mmadụ insulin 100 IU (3,571 mg),
ndị na-ebu ụzọ: 85% glycerol, protamine sulfate, metacresol, phenol, zinc chloride, sodium hydrogen phosphate dihydrate, sodium hydroxide, acid hydrorated, mmiri maka injection.
Ngwa ngwa gbasasaa nkwusioru nke ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha. Onye ike karịrị nke mmadụ bụ transperent ma ọ bụ ihe na-apụtakarị.
Ngwongwo ogwu
Mlọ ọgwụ
Ọnwụ® Basal GT (isofan-insulin kwụsịtụrụ) bụ insulin nwere mmụba nke nwayọ na ogologo oge. Mgbe nchịkwa subcutaneous gasịrị, nsonaazụ ahụ na-apụta n'ime nkeji 60, a na-ahụ usoro nke kachasi ihe dị ka awa 3-4 mgbe ịgba ntụtụ ahụ, nsonaazụ ahụ dịruru 11-20 awa.
Ọkara ọkara nke insulin site na ọbara bụ ihe dị ka nkeji isii na isii. Ọ bụ ogologo oge na nnukwu gbasara akụrụ odida. Okwesiri iburu n'uche na ọgwụ ọgwụ nke insulin anaghị egosipụta mmetụta metabolic ya.
Mlọ ọgwụ
Ọnwụ® Basal HT nwere insulin yiri nke ahịrị n’ime insulin, nke enwetara site na iji teknụzụ DNA jikọtara ọnụ na iji ya Escherichia coli.
Ọnwụ® Bazal GT
- na - ebelata glucose ọbara ma na - eso akpata anabolic, ma na - ebelata mmetụta catabolic
- na - akwalite mbufe nke glucose na sel, yana ịkpụkọta glycogen na akwara na imeju na - eme ka ojiji nke pyruvate rụọ ọrụ. Ọ na-egbochi glycogenolysis na glyconeogenesis
- na-akwalite lipogenesis na imeju na anụ ahụ na-adị adipose ma na-egbochi lipolysis
- na - akwalite oriri nke amino acid site na mkpụrụ ndụ ma na - eme ka njikọ protein
- Ọ na - eme ka mkpụrụ ndụ potassium na - eme ka mmadụ bukwuo ibu.
Usoro onunu ogwu na nhazi
A na-ahọrọ ọkwa glucose ọbara chọrọ, nhazi insulin ka ọ ga-eji mee ihe na usoro usoro (usoro, nkesa oge) n'otu n'otu dabere na nri, ọkwa nke mmega ahụ na ụzọ ndụ onye ọrịa.
Usoro onunu ogwu ubochi na oge ochichi
Enweghị iwu a na-apụghị ịgbagha agbagha maka ịsingụ insulin. Ogo insulin kwa ụbọchị chọrọ bụ 0-1-1.0 IU kwa kilogram nke ịdị arọ ahụ. Ihe ndi mmadu choro iji mee ka insulin bu 40-60% nke ihe ha choro kwa ubochi. Ọnwụ® A na-achịkwa Bazal GT n'ime minit 45-60 tupu nri.
Nkezi nke abuo
Controlkwalite njikwa metabolic nwere ike iduga ụba insulin, na-eduga n'ịchọrọ insulin ala. Enwere ike ịchọ ndozi nke mgbanwe ma ọ bụrụ na mgbanwe na ogo onye ọrịa, ụzọ ndụ ya, na ọnọdụ ndị ọzọ nwere ike itinye aka na ụba hypoglycemia ma ọ bụ hyperglycemia (lee “ntuziaka pụrụ iche”).
Ndị otu ọrịa pụrụ iche
Enwere ike belata mkpa nke insulin ma ọ bụrụ na ọ nwere ọrụ imeju ma ọ bụ ọrụ akụrụ na oge agadi (lee "ntuziaka pụrụ iche").
A na-ewepụ nlekọta intraven.
Ọnwụ® Bazal GT na-achịkwa subcutaneously.
Ntinye insulin na, yabụ, ike ịbelata shuga na ntụtụ ahụ nwere ike ịdị iche, dabere na saịtị ịgba agba (dịka ọmụmaatụ, mgbidi nwa dị na etiti mpaghara feminin). Ekwesịrị ịgbanwe saịtị ntụtụ ahụ n'oge ọ bụla n'ime otu mpaghara ahụ.
Mlọ ọgwụ
Insuman ® Basal GT nwere insulin yikwara n’otu nhazi ya na insulin nke mmadụ wee nweta site na njikwa mkpụrụ ndụ ihe nketa site na iji ụdị Escherichia coli K12 135 pINT90d.
Usoro usoro insulin:
Na -ebelata mkpụkọ nke glucose n'ọbara, na-akwalite mmetụta anabolic ma belata mmetụta catabolic,
Ọ na-abawanye njem glucose n'ime mkpụrụ ndụ yana nguzobe nke glycogen na akwara na umeji ma na - eme ka ojiji nke pyruvate, gbochie glycogenolysis na glyconeogenesis,
Na-abawanye lipogenesis na imeju na anụ ahụ adipose ma na-egbochi lipolysis,
Na-akwalite nha nke amino acid n’ime sel na njikọ protein,
Ọ na - eme ka ihe ndị na - eme nri na - emewanye ụbara.
Insuman ® Bazal GT bụ insulin na-arụ ọrụ ogologo oge nke nwere usoro nwayọ nwayọ. Mgbe nchịkwa sc, mmetụta hypoglycemic na-apụta n'ime awa 1 ma rute karịa n'ime awa 3-4. Mmetụta ahụ na-adịgide ruo awa 11-20.
Ihe ngbanwe
ntụgharị uche nke insulin ma ọ bụ n'ihe ọ bụla inyeaka nke ọgwụ ahụ, belụsọ ma usoro insulin dị mkpa,
Iji nlezianya: ọdịda akụrụngwa (enwere ike ibelata insulin chọrọ n'ihi mbelata nke insulin metabolism), ndị ọrịa agadi (mbelata nke ọrụ akụrụ nwere ike ibute ịrị elu insulin na-arịwanye elu), imeju imeju (chọrọ insulin nwere ike ibelata n'ihi mbelata ikike gluconeogenesis na ibelata metabolism metabolism), nnukwu ihe siri ike nke akwara ọbara na akwara ụbụrụ (na ndị ọrịa a, ọrịa hypoglycemic nwere ike inwe ihe pụrụ iche gbasara ahụike, i.e. K. enwere ohere dị ukwuu nke ọrịa obi ma ọ bụ ọrịa ụbụrụ nke hypoglycemia), ndị ọrịa nwere ọrịa retinopathy na-abawanye uru, ọkachasị ndị na-enwetaghị ọgwụgwọ na photocoagulation (ọgwụgwọ laser), n'ihi na ọrịa hypoglycemia enwere ihe ize ndụ nke amaosis na-adịte aka - kpuru ìsì zuru oke, ndị ọrịa nwere ọrịa intercurrent (n'ihi na ọrịa intercurrent na-abawanye mkpa nke insulin).
Ọ bụrụ na onye ọrịa ahụ nwere otu n'ime ọrịa ndị a ma ọ bụ ọnọdụ ndị a, ịkwesịrị ịgakwuru dọkịta gị tupu ị usingụ ọgwụ ahụ.
Ime na lactation
Ọgwụgwọ Insuman ® Basal GT mgbe a dị ime kwesịrị ịga n’ihu. Insulin anaghị agafe ihe mgbochi placental. Maintenancenwe ọgwụ mgbochi ọrịa n'ụzọ dị mma n'oge afọ ime bụ ihe dịịrị ndị inyom nwere ọrịa shuga tupu ime ime, ma ọ bụ maka ndị inyom nweela ọrịa shuga.
Mkpa insulin n'oge ime nwere ike ibelata n’oge ọnwa atọ mbụ dị n’afọ nke afọ ime, ọ na-agbadakarị n’oge ọnwa nke abụọ na nke atọ. Ozugbo amụrụ nwa, ọgwụ insulin na-agbada ngwa ngwa (ohere dị ukwuu nke hypoglycemia). N’ime afọ ime, ọkachasị mgbe amụchara nwa, a chọrọ iji nlezianya leba anya n’obara glucose na ọbara.
Ọ bụrụ na ị dị ime ma ọ bụ na-eme atụmatụ ịtụrụ ime, jide n’aka gwa dọkịta gị.
N'oge a na-enye nwa ara, enweghị mgbochi ọ bụla na usoro ọgwụgwọ insulin, agbanyeghị, enwere ike ịchọrọ insulin ọgwụ na ịmegharị nri.
Nsonaazụ
Hypoglycemia. Mmetụta mmetụta insulin na-enwekarị nwere ike ịmalite ma ọ bụrụ na ọgwụ insulin na-eduzi karịrị mkpa ọ dị (lee “Ntuziaka Pụrụ Iche”). Ọnọdụ siri ike ugboro ugboro nke hypoglycemia nwere ike ibute mmepe nke mgbaàmà akwara, gụnyere coma, cramps (lee “doụbiga ya ókè”). Ogologo oge ma ọ bụ nnukwu nsogbu nke hypoglycemia nwere ike ịnwe ndụ.
N'ọtụtụ ndị ọrịa, mgbaàmà na ngosipụta nke neuroglycopenia nwere ike ibute akara nke mgbanwe mgbanwe (na nzaghachi na ịmalite hypoglycemia) nke sistemụ ọmịiko ọmịiko. Ọtụtụ mgbe, iji nkwupụta dị mkpịsị ma ọ bụ belata ngwa ngwa karị n'ọbara glucose n'ọbara, ihe nrịba ama nke ịgbanyụ ọrụ nke sistemụ ọmịiko na ihe mgbaàmà ya na-ekwupụta karịa.
Site na mbelata nke ukwuu na glucose n'ọbara, mmepe nke hypokalemia (nsogbu site na CCC) ma ọ bụ mmepe nke ọrịa ụbụrụ ga-ekwe omume.
Ihe ndi a bu ihe ojoo ndi choputara na nnwale nke ulo ogwu nke ndi mmadu n’agha site n’usoro ahu ma n’usoro n’ibelata ngbanwe: otutu oge (≥1 / 10), otutu oge (≥1 / 100 na nke ohuru, nke endocrinologists nyere maka Nyochaa Ọrịa Shuga Na-aga n'ihu! Ọ bụ naanị na ọ dị mkpa kwa ụbọchị.
Ọgwụ a bụ ngwaahịa nke Sanofi, nke na -emepụta ihe ama ama Lantus, Apidra na Tujeo. Sharekè insuman na ahịa insulin bụ ihe dị ka 15%. Dabere na ndị na-arịa ọrịa shuga, ngwọta a dị mma iji ya, mara ya mgbe niile. Enwere ụdị insulin abụọ n'usoro: insuman Bazal na-ajụ na obere Insuman Rapid dị mkpụmkpụ.
Kedu ka ọgwụ ahụ si arụ ọrụ?
Insuman bụ insulin sitere na mkpụrụ ndụ mmadụ. N'usoro nke ụlọ ọrụ mmepụta ihe, a na-emepụta hormone ahụ site na iji nje bacteria. E jiri ya tụnyere insulins ndị a na-emebu, injin sitere na mkpụrụ ndụ ihe nketa nwere mmetụta kwụsiri ike na nhicha mma.
Na mbụ, ebumnuche nke ọgwụ insulin bụ ịlụ ọgụ ọnwụ. Site na mbata insulin nke mmadụ, ihe ịma aka a agbanwewo. Ugbu a anyị na-ekwu maka iwelata ihe ize ndụ nke nsogbu na ndụ zuru oke nke ndị ọrịa. N'ezie, imezu nke a na analogs insulin dị mfe, mana na insuman kwụsiri ike maka ọrịa shuga enwere ike. Iji mee nke a, ịkwesịrị iji nlezianya gụọ ntuziaka maka ọgwụ, profaịlụ nke omume ya, mụta ma dozie ya n'oge.
Ọrịa shuga na oke nrụgide ga-abụ ihe mgbe ochie
Ọrịa shuga bụ ihe na-akpata ihe fọrọ nke nta ka ọ bụrụ 80% nke ọrịa strok na mgbatị niile. 7 n’ime mmadụ 10 n’ime mmadụ na-anwụ n’ihi akwara mkpụrụobi ma ọ bụ ụbụrụ nwere oghere. N'ihe fọrọ nke nta ka ọ bụrụ okwu niile, ihe kpatara njedebe a dị oke egwu bụ otu - shuga dị n'ọbara.
Enwere ike ịkwatu shuga, ma ọ bụghị. Mana nke a anaghị agwọ ọrịa ahụ n'onwe ya, kama ọ na - enyere aka ịlụ ọgụ nyocha, ọ bụghị ihe kpatara ọrịa ahụ.
Naanị ọgwụ akwadoro maka ọrịa shuga na ndị endocrinologists jiri rụọ ọrụ ha bụ Dzhi Dao Diabetes Adhesive.
Ofgwọ ọgwụ dị irè, gbakọọ dịka usoro ọkọlọtọ (ọnụọgụ ndị ọrịa ndị gbakere na ọnụọgụ ndị ọrịa nọ n’otu narị mmadụ 100 e si nweta ọgwụgwọ) bụ:
- Normalization shuga - 95%
- Mwepu nke akwara mbufụt - 70%
- Mwepu nke obi di obia - 90%
- Bibie ọbara mgbali elu - 92%
- Ime ka ubochi di elu, meghari ura n'abali - 97%
Ndị na-emepụta Ji Dao abụghị nzukọ azụmahịa, steeti na-akwụkwa ya ụgwọ. Ya mere, ugbu a onye obibi ọ bụla nwere ohere ịnweta ọgwụ ahụ na mbelata 50%.
Ngwakọta nke homonụ ahụ n’akpa ike nwere adịghị agbanwe agbanwe. Ntọhapụ kachasị nke insulin na-eme na nzaghachi na glucose na-abanye na arịa ọbara site na nri. Agbanyeghị, ọ bụrụ na agụụ na-agụ mmadụ ma ọ bụ hie ụra, a ka nwere insulin n'ọbara, n'agbanyeghị nke pere mpe - n'ogo a na-akpọ basal. Mgbe mmepụta nke homonụ na-akwụsị site na ọrịa shuga, a na-amalite ọgwụgwọ mkpụrụ ọgwụ. Nke a na - achọkarị insulin 2. Ọkwa basal na-e Insomi Insuman Bazal, ọ na-abanye n'ọbara nwayọ nwayọ, ogologo oge yana obere akụkụ. Ejiri shuga mgbe o risịrị nri iji belata Insuman Rapid, nke na-erute arịa ndị ahụ ọsọsọ.
Atụmatụ iche nke Insumans:
Ihe ngosiputa | GT ọsọ | Bazal GT | |
Ngwakọta | Insulin nke mmadụ, ihe ndị na-ebelata nsogbu ịgwọ ọrịa, ihe ndị na-agbazi acidity. Ndị na - arịa ọrịa Allergy kwesịrị ịmata onwe ha na ndepụta nke ndị ọbịa akọwapụtara na ntuziaka ahụ. | Iji mee ka homonụ nke nwayọ nwayọ site na anụ ahụ dị n'okpuru ala, a na-etinye sọlfọ protamine na ya. A na-akpọ njikọ a insulin-isophan. | |
Otu a | Short | Ọkara (ewere ogologo oge ruo mgbe insulin analogues pụtara) | |
Profaịlụ nke omume, awa | mbido | 0,5 | 1 |
elu | 1-4 | 3–4, ọnụ ọgụgụ kasị elu adịghị ike. | |
oge | 7-9 | 11-20, ka ị theụ ọgwụ dị elu, ogologo oge ị na-eme ya. | |
Ihe na-egosi | Usoro ọgwụgwọ insulin maka ụdị 1 na ụdị ọrịa ogologo oge ogologo 2. Imezi nnukwu nsogbu ọrịa shuga, gụnyere ọgwụ na-abụghị insulin. Nwa oge maka oge ịba ụba hormone chọrọ. Nwa oge banyere contraindications maka iwere mbadamba shuga dị ala. | Naanị ọrịa shuga na-akpata insulin. Enwere ike iji ya na-enweghị Rapid HT ma ọ bụrụ na insulin chọrọ ala. Iji maa atụ, na mmalite insulin ọgwụ, ụdị shuga 2. | |
Ofzọ nlekọta | N'ụlọ - subcutaneously, na ụlọ ọgwụ - intravenously. | Naanị subcutaneously na mkpịsị mkpụrụ osisi ma ọ bụ U100 insulin. |
Iwu ntinye
Mkpa insulin bụ otu onye maka ndị ọrịa mamịrị ọ bụla. Dịka iwu, ndị ọrịa nwere ụdị 2 na oke ibu chọrọ hormone ọzọ. Dabere na ntuziaka maka ojiji, ná nkezi kwa ụbọchị, ndị ọrịa na-abanyekwa otu 1 ọgwụ ọgwụ kwa kilogram nke ịdị arọ. Onu ogugu a gụnyere Insuman Bazal na Rapid. Short insulin nwere 40-60% nke ngụkọta mkpa.
Insuman Bazal
Ebe Insuman Bazal GT na-arụ ọrụ na-erughị otu ụbọchị, ị ga-abanye ya ugboro abụọ: n'ụtụtụ mgbe ị nwesịrị shuga na tupu ịlakpu ụra. A na-agbakọ doses maka nchịkwa ọ bụla iche. Maka nke a, enwere usoro pụrụ iche nke na-eburu n'uche mmetụta nke homonụ na glycemia. Dose kwesịrị ekwesị kwesịrị idobe ọkwa shuga n’oge agụụ na-agụ onye na-arịa ọrịa shuga.
Insuman Bazal bụ nkwusioru, mgbe a na-echekwa ya: a ga-edozigharị usoro a kachasị elu, ntụpọ ọcha dị na ala. Tupu ntụtụ ọ bụla, ọgwụ ahụ na pen mkpa mix ọma . Ọ bụrụ na nkwụghachi ahụ na-eyiwanye otu, ka a ga-eweghachi ọgwụ ole achọrọ. Insuman Bazal dị mfe ịkwadebe maka nchịkwa karịa insulins ndị ọzọ. Iji mee ka agwakọta, a na-eji bọọdụ atọ kwoo cartridges, nke na-eme ka o kwe omume ịnweta ụdị nke nkwusioru ahụ zuru oke na 6 pensụl syringe.
Njikere iji Insuman Bazal nwere otu ocha di otu. Ihe ịrịba ama nke mmebi nke ọgwụ ahụ bụ flakes, kristal, na blot nke agba dị iche na kadi ahụ mgbe agwakọchara.
Insuman Rapid
Short Insuman Rapid GT gbara tupu nri, ọ na-abụkarị ugboro atọ n'ụbọchị. Ọ na-amalite ịrụ ọrụ mgbe nkeji iri atọ gachara, yabụ, a gharịrị ibido ya tupu oge eruo. Iji meziwanye ụgwọ nke ọrịa shuga, ọ bụ ihe na-achọsi ike inweta ọnọdụ nke nnabata nke insulin na glucose n'ọbara.
Iji mee nke a, ịchọrọ:
- Jiri nri carbohydrates na protein dị nwayọ malite nri gị. A na-ahapụ carbohydrates ngwa ngwa na njedebe nke nri.
- Ghichaa ntakịrị n’etiti isi nri. Maka nri nri, carbohydrate 12-20 g zuru ezu.
A na-ekpebi ọnụọgụ nke Insuman Rapid site na ego nke carbohydrates na nri na nri na-esote. Ọgụgụ a gụpụtara n'ụzọ ziri ezi na-enye gị ohere iwepu shuga niile ejiri nri.
Insulin ngwa ngwa na-apụta ìhè mgbe niile, ịkwesighi ịgwakọta ya, enwere ike iji pen sirinji na-enweghị nkwadebe.
Usoro ogwu
Emepụtara insuman site na ụdị nke mepụtara 5 ml vials, cartilges 3 ml na mkpịsị mkpụrụ sili. N'ime ụlọ ahịa ọgwụ Russia, ọ kachasị mfe ịzụta ọgwụ etinyere na pensụl syringe SoloStar. Ha nwere insulin 3 nke insulin na enweghi ike iji ya mgbe ọgwụchara ya mechara.
Uzo esi abanye insuman:
- Iji belata ihe mgbu nke ntụtụ ma belata ihe ize ndụ nke lipodystrophy, ọgwụ dị na pen sirinji kwesịrị ịdị na nrị okpomọkụ.
- Tupu iji ya, a na-enyocha Cartridge ahụ nke ọma maka ihe ịrịba ama nke mmebi. Ka onye ọrịa wee ghara iduhie ụdị insulin, a na-eji mkpịsị agba nwere akara agba nke kwekọrọ na agba nke ihe edetu na ngwugwu ahụ. Insuman Bazal GT - akwụkwọ ndụ akwụkwọ ndụ, Rapid GT - edo edo.
- A na-akpọgharị Insuman Bazal n'agbata n'ọbụ aka ọtụtụ oge ịgwakọta.
- A na-ewere agịga ọhụrụ maka ntụtụ ọ bụla. Jiri ihe mebiri emebi nke anụ ahụ dị n’okpuru. Ọ bụ agịga ọ bụla dị n'ụwa niile dị ka pensụl nke SoloStar: MicroFine, Insupen, NovoFine na ndị ọzọ. A họrọ ogologo nke agịga dabere na ọkpụrụkpụ nke subcutaneous abụba.
- Mkpịsị sirinji na-enye gị ohere ịgụnye ọnụego 1 ruo 80. Insumana, izi ezi dosing - 1 unit. N’aka umuaka na ndi oria n’aricha nri carbohydrate, mkpa homonu nwere ike di obere, ha choro izizi di elu karie onodu ogwu. SoloStar adabara ụdị ikpe a.
- Ọ kacha mma ka a na-enyocha insuman Rapid na afọ, Insuman Bazal - na apata ụkwụ ma ọ bụ n'akụkụ ikpere.
- Mgbe iwebata usoro ahụ, agịga ahụ dị n'ahụ ahụ maka sekọnd iri ọzọ ka ọgwụ ahụ amalite ịpụ.
- Mgbe ọ bụla ị gachara, a na-ewepụ agịga. Insulin na-atụ egwu anwụ, yabụ ịkwesịrị iji okpu mechie katriel ozugbo.
Mmetụta akụkụ
Ọ bụrụ na a na-enye ọgwụ ahụ karịa ka achọrọ, ọ na-apụta. Ọ bụ ya bụ mmetụta na-esokarị ọgwụ insulin, n'agbanyeghị ụdị insulin eji. Hypoglycemia nwere ike ịka njọ ngwa ngwa, yabụ na ntakịrị ntakịrị shuga dị n'okpuru ala kwesịrị iwepụ ya ozugbo.
Ihe mmetụta Insuman gụnyekwara:
Dọkịta nke Sciences Medical, Isi nke Institute of Diabetology - Tatyana Yakovleva
M na-amụ ọrịa shuga kemgbe ọtụtụ afọ. Ọ na-atụ ụjọ mgbe ọtụtụ mmadụ nwụrụ, nweekwa nkwarụ karịa n'ihi ọrịa shuga.
Emere m ngwa ngwa izisa ozi ọma - Endocrinological Research Center nke Russian Academy of Medical Sciences jisiri ike mepụta ọgwụ na-agwọ ọrịa shuga kpamkpam. N'oge a, ịdị irè nke ọgwụ a na-eru nso 98%.
Ozi ọma ọzọ: Ministri Ahụike echekwaala maka mmemme pụrụ iche nke na-akwụ ụgwọ ọgwụ dị elu. Na Russia, ndị ọrịa mamịrị ruo Eprel 23 (nke gụnyere) nwere ike inweta ya - Naanị 147 rubles!
- Allergy na akụkụ nke ihe ngwọta. A na-egosikarị ya na itching, redness, friza na mpaghara nchịkwa. Ọtụtụ mgbe, (dị ka ntuziaka a si kwuo, ihe na-erughị 1%) mmeghachi omume anaphylactic eme: bronchospasm, edema, mbelata mgbali, ujo.
- Njide sodium. A na-ahụkarị ya na mbido ọgwụgwọ, mgbe shuga sitere na ọnụọgụ dị elu na-adalata na nkịtị. Hypernatremia na-esoro edema, ọbara mgbali elu, akpịrị ịkpọ nkụ, oke iwe.
- Formationmepụta ọgwụ mgbochi ọrịa na-egbochi insulin n'ime ahụ bụ ihe e ji mara insulin ọgwụ ogologo oge. N'okwu a, mmụba na ọgwụ insuman chọrọ. Ọ bụrụ na ọgwụ achọrọ buru oke ibu, a na-enyefe onye ọrịa ahụ n'ụdị insulin ọzọ ma ọ bụ ọgwụ ọgwụ immunosuppressive ka edepụtara ya.
- Ọganiihu n’ụzọ dị ịtụnanya na-akwụ ụgwọ ọrịa shuga nwere ike ibute nkwarụ anya nke nwa oge.
Ọtụtụ mgbe, ahụ na-eji nwayọ arụ ọrụ insulin, ọnya ahụ akwụsị. Ọ bụrụ na mmetụta otu akụkụ na-eyi ndụ egwu (nsogbu anaphylactic) ma ọ bụ na-apụ n'anya mgbe izu abụọ gachara, ọ ga-adị mma iji dochie ọgwụ ahụ na analog. Insuman Bazal GT - ma ọ bụ, Rapid GT -, ma ọ bụ Regular Humgular. Ọgwụ ndị a dị iche naanị Profaịlụ a na-eme ihe bụ otu maka ha. Mgbe ha nwere insulin nke mmadụ, ọ na-agbanwe insulin analogues.
Ọnụ ego insuman dị ka ọnụ ahịa ụtụ isi ya. Ọgwụ a na-eji sirinji eji ihe dị ka 1100 rubles. kwa 15 milimita (nkeji 1500, mkpụrụedemede 5). Isofan-insulin bu ihe edere na listi ogwu di nkpa, ya mere ndi oke oria ji eme ya ikike ịnata ya n'efu .
Ntụziaka pụrụ iche
Hypoglycemia bụ mmetụta kachasị njọ nke ịgwọ ọrịa insulin, ya mere akụkụ dị iche iche nyefere ya na ntuziaka maka ojiji nke Insuman. Ihe ọghọm nke ịdaba na shuga dị oke elu na mbido insulin iji, mgbe onye ọrịa na-amụ naanị ịgbakọ ọnụọgụ ọgwụ. N'oge a, a na-atụ aro nlele glucose dị ukwuu: a na-eji mita ahụ ọ bụghị naanị n'ụtụtụ na tupu nri, kamakwa na oge.
A na-akwụsị hypoglycemia na mgbaàmà mbụ ma ọ bụ na ọ nwere obere shuga, ọ bụrụgodị na ọ naghị emetụta ọdịmma ahụ. Ihe ịrịba ama nke ihe egwu: ụjọ, agụụ, ịma jijiji, ịmụmụ ọnụ ma ọ bụ mkpọtụ nke ire na egbugbere ọnụ, ọsụsọ, mkpọnwụ isi, isi ọwụwa. Mmụba nke hypoglycemia nwere ike bụrụ ihe a na-enyo enyo nke nkwarụ, njide onwe onye na-ahazi na nhazi nke mmegharị. Mgbe mmụọ mpụsịrị, ọnọdụ ahụ ga-akawanye njọ, malitere.
Ọ bụrụ na ọrịa shuga na-adịkarị ala na-abịakarị, ihe na-aka njọ ka ọrịa mamịrị na-egosi mgbaàmà ya, na-adịwanye njọ ịdalata shuga na-esote. Udiri hypoglycemia ugboro ugboro na-achọ nhazi nke dose nke Insuman. Ihe enyemaka mbu maka shuga dị ala - 20 g glucose . Enwere ike ịgafe dose a na oke ikpe, ebe oke carbohydrates ga-eduga ngwa ngwa n'ọdịdị na - abụghị hyperglycemia.
Mgbagha nke hyperglycemia siri ike bụ. Ọ na - etolite ruo ọtụtụ ụbọchị, yabụ onye ọrịa nwere oge ime ihe. N'ọnọdụ ụfọdụ, site na mmalite nke ketoacidosis ruo coma, ọ bụ naanị awa ole na ole gafere, yabụ ịkwesịrị belata shuga dị elu ozugbo achọpụtara ya. Maka ebumnuche ndị a naanị adịghị ngwa ngwa . Dịka iwu zuru oke, achọrọ 1 iji belata glycemia site na 2 mmol / L. Ọnwụ. Iji gbochie hypoglycemia, a na-ebelata shuga na ọkwa mbụ ka ọ bụrụ 8. Ọ na-eme nrụzi maka ụkpụrụ ka ọ gachara awa ole na ole, mgbe oge ọnya mbụ ahụ agwụla.
Gbalia imuta! You chere na nchịkwa ọgwụ ogologo oge na ọgwụ bụ naanị ụzọ eji egbochi shuga? Ọ bụghị eziokwu! Nwere ike ịchọpụta nke a n'onwe gị site na ịmalite iji ya.
**** HOECHST MARION ROUSSEL Aventis Pharma Deutschland GmbH Sanofi-Aventis Deutschland GmbH / Sanofi-Aventis East Hoechst Marion Russel GmbH
Ọnọdụ pụrụ iche
- insulin-isophan (injinia mmadụ) 3.571 mg (100 IU) Ndị pụrụ iche: protamine sulfate - 318 μg, metacresol (m-cresol) - 1.5 mg, phenol - 600 μg, zinc chloride - 47 μg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (maka ịhazi pH) - 576 μg, hydrochloric acid (maka imezi pH) - 246 μg, mmiri d / i - ruo 1 ml. insulin-isophan (injinia mmadụ) 3.571 mg (100 IU) Ndị pụrụ iche: protamine sulfate - 318 μg, metacresol (m-cresol) - 1.5 mg, phenol - 600 μg, zinc chloride - 47 μg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (maka ịhazi pH) - 576 μg, hydrochloric acid (maka imezi pH) - 246 μg, mmiri d / i - ruo 1 ml.
Leasedị ntọhapụ, ihe mejupụtara na nkwakọ
Buyzụta Insuman Bazal GT nwere ike ịbụ n'ụdị nkwusioru maka injections n'okpuru anụ ahụ na usoro nke 100ME / ml. Otu karama iko nke ọ bụla nwere 5 ml Insuman Bazal GT ma mechie ya okpu aluminom nke ejiri okpu plastik kpuchie n’elu maka nchekwa. Enwere karama 5 n’ime ngwugwu kaadiboodu. Na ntinye, ogwu a di na ngwongwo iko nke 3 mil. N'otu akụkụ, ọ na-emechi emechi ma kpuchie ya na aluminom, na nke abụọ - site na ọkpọ. Cartridge ahụ nwere bọọlụ bọọlụ atọ. A na-eji mpempe akwụkwọ ise dị otú ahụ ebu.
Omume ọgwụ
Insulin na-ebelata glucose, na-akwado ibụkịkọta ogige ọhụrụ ma na --ebelata mmetụta catabolic. Ọgwụ na-akwalite mmegharị nke glucose site na mkpụrụ ndụ ma mezie glycogen. Nsonaazụ nke mmeghe n’okpuru anụ ahụ na-apụta n’ime otu elekere, ọ ga-akacha ka elekere atọ gachaa werekwa site n’agbata awa iri na otu ruo n’awa iri abụọ. Usoro T1 / 2 bụ nkeji 5, ma ọnụnọ nke ọdịda akụrụ, ọ na-abawanye nke ukwuu.
A na-eji insuman Bazal GT mee ihe maka ọrịa shuga, nke chọrọ iwebata insulin ọzọ.
Dodoụbiga ya ókè
Doụbiga ọgwụ ike ókè, dịka ọmụmaatụ, iwebata ọgwụ riri oke n’ihe metụtara nri ma ọ bụ ume ike riri, o nwere ike ibute ngosipụta hypoglycemia, nke nwere ike bụrụ ezigbo ihe egwu, na ọnwụ. Maka ọgwụgwọ nke ọrịa hypoglycemia nke obere ihe mgbagwoju anya, mgbe onye ọrịa ahụ na-enwe mmụọ nke ọma, kwụsị iji nri carbohydrate. May nwere ike ịhazigharị ọnụọgụ, gbanwee iwu yana ugboro ole a na-eri nri ma mezie ogo ihe omume n’egwuregwu. Ọnọdụ nsogbu ndị ọzọ siri ike nke hypoglycemia, nke enwere ike ijikọ ya na steeti comotose, ihe mgbu ma ọ bụ malfunctions na akwara ozi, nwere ike ịkwụsị site na nchịkwa nke glucagon intramuscularly ma ọ bụ subcutaneously, ma ọ bụ iwebata usoro ị nwere ike ịche dextrose site na akwara. Maka ụmụaka, mkpebi nke dose nke dextrose sitere na oke ahụ ha. Ozugbo ịba ụba glucose bilitere, ọ nwere ike ịdị mkpa iri nri ndị nwere carbohydrate ma chịkwaa dọkịta na-aga, n'ihi na mgbe ọgwụgwọ mbụ nke mgbaàmà hypoglycemia, ọ nwere ike ịmaliteghachi. Mgbe ị na-emeso ụmụaka, ọ dị mkpa iji nlezianya nyochaa ọdịnaya glucose, n'ihi na ọ nwere ike ịbụ na ngosipụta dị ukwuu nke agụụ agụụ ga-amalite. N'ihe banyere hypoglycemia siri ike ogologo oge mgbe iji glucagon ma ọ bụ dextrose, ọ dị mkpa iji tinye otu dropper na oke ịta nke dextrose iji zere ikpe nke ịmalite agụụ agụụ ọzọ. Na mgbakwunye, ọ bara uru ịtụle na ụfọdụ ọnọdụ nwere ike ịchọ njem mmadụ na ngalaba nlekọta ahụ ike maka ịchịkwa ọnọdụ ya na ịchịkwa usoro ọgwụgwọ niile.
Mkparịta ụka ọgwụ ọjọọ
Mkparịta ụka nke Insuman Bazal GT na ọgwụ ndị ọzọ nwere ike ịdị ka nke a: 1. Site na beta-blockers, clonidine, nnu nke lithium - mbelata mmetụta hypoglycemic nke ọgwụ. 2. Site na ethanol - mbelata mmetụta hypoglycemic nke ọgwụ, mmụba n'ihe ize ndụ nke ịmalite agụụ agụụ, yana mbelata glucose na-aba uru na-etinye ahụike na ndụ egwu. 3. Site na pentamidine - nsogbu dị elu nke ịbawanye ike agụụ, nke nwere ike ịbanye na hyperglycemia. 4. Site na ọgwụ ọmịiko - mbelata ma ọ bụ wepu ya kpamkpam nke mgbaàmà nke usoro ụjọ ahụ.
Ime na lactation
N'oge afọ ime, ọ dị mkpa ka ị gaa n’ihu na-ewere Insuman Bazal GT. Ọ bara uru ikwu na insulin enweghị ike ịbanye na Plasenta. Ọ dị mkpa ka ịchịkwa usoro metabolic n'oge afọ ime maka ndị a chọpụtara n'ọrịa shuga mellitus tupu oge ịtụrụ ime, na ndị nke ọrịa mgbatị afọ mellitus malitere ịpụta n'oge afọ ime. N’ime oge izizi, mkpa insulin nwere ike belata, mana enwere mmụba nke insulin na nke abụọ na nke atọ. Mgbe ịmụchara nwa, mkpa insulin na-ebelata ngwa ngwa, nke na-eduga n'ịba ụba nke ịmalite agụụ agụụ. Achọrọ iji nlezianya nyochaa glucose n'oge afọ ime yana ozugbo amụchara ya. Mgbe ị na-eme atụmatụ ịtụrụ ime na mgbe ọ mere, ọ dị mkpa ịgwa ndị dibia bekee banyere nke a. Tupu ịmalite ime atụmatụ, ịkwesịrị ịgakwuru dọkịta gị ma chọpụta njirimara niile nke otu esi akwadebe maka ịtụrụ ime, yana ihe ịrịba ama nke mbụ. Ọ dị mkpa iburu n'uche na n'oge ị na-enye nwa ara, enweghị mgbochi ọ bụla na ojiji nke insulin, mana na-eburu n'uche mmezi nke insulin ọgwụ na nri.
Ọnọdụ nchekwa
- debe ebe nkụ
- Chekwaa na oyi na-atụ (t 2 - 5)
- zere ụmụaka
- chekwaa n’ebe gbara ọchịchịrị
- Biogulin Tape U40, Isofan Insulin World Cup, Levulin L, Levulin N, Monotard, Humulin L, Humulin N
Ogologo oge insulin mmadụ
Mlọ ọgwụ
N'ebe ndị dị mma, T 1/2 nke insulin plasma dị ihe dị ka nkeji isii na isii. N'ime ndị ọrịa nwere nnukwu nsogbu gbasara akụrụ, ọ dị ogologo. Agbanyeghị, ekwesịrị ịmara na ọgwụ ọgwụ nke insulin anaghị egosipụta mmetụta metabolic ya.
Na-egosi Insuman ® Bazal GT
Ọrịa shuga mellitus chọrọ ọgwụgwọ insulin.
Ngwongwo na-agwọ ọrịa
A na - enweta mmetụta hypoglycemic nke Insuman Bazal n'ihi akụkụ ya - insulin-isophan. Ihe dị n’ime ya na akụrụngwa ya na homonụ na-ahụ n’ahụ mmadụ. A na - enweta ya site na inyocha mkpụrụ ndụ ihe nketa.
Ọgwụ bụ otu nke ọgwụ ọgwụ ọkara nke ihe. Mgbe ọ gbasasịrị, subcutaneously na-ejikọ ụfọdụ ndị nabatara ụkwara akpụkpọ ahụ, na-akpụ otu ihe arụ ọrụ nke na - arụ ọrụ na --aga n'ihu usoro ntanetị. Ọ na - ebelata glucose site na ime ka ọ na - eme njem, na - eme ka mmiri na - ebelata, na - egbochi njikọta imeju, na - etinyekwa usoro metabolic na ntinye ya.
Ogologo oge mmetụta ọ na-enye na ọgwụ ahụ na-adabere na ọsọ nke a na-etinye insulin na ahụ, ọ̀gwụ, mpaghara injection, na ụzọ nchịkwa. Ya mere, insulin na-arụ ọrụ ọ bụghị naanị na ndị ọrịa mamịrị dị iche iche, kamakwa na otu onye ọrịa.
Nkezi isofan ụkpụrụ: mmalite nke ime ihe - otu elekere na ọkara mgbe a gbasesịrị, gosipụtara mmetụta kachasị elu na nkeji nke awa 4-12, oge hypoglycemic edinam - ruo otu ụbọchị.
A na-ekesa ọgwụ ahụ n’akụkụ anụ ahụ dị iche iche, ọ nweghị ike ịgafe n’ime mmiri ara ehi na-agafekwa na Plasenta. A na-etinye ya n'ọrụ buru oke ibu na imeju na akụrụ. Ọ na-apụta ya na mmamịrị.
Mkparịta ụka ọgwụ ọjọọ
N'oge insulin na-aga, a ga-eburu Insuman Bazal GT n'uche na mgbe ejikọtara ya na ụfọdụ ọgwụ, mgbanwe mgbanwe hypoglycemic ma ọ bụ mgbanwe nke ọgwụgwọ ọgwụgwọ nke ọgwụ ndị ọzọ ga-ekwe omume:
- A na-eme ka mmetụta nke hypoglycemic nke Insuman dịkwuo elu ma na-agbatịkwu mgbe a na-ejikọta ya na ọgwụ ndị na-eme ka mmiri ghara ịdalata, ACE inhibitors, iMAO, Disoprimide, salicylates, anabolics, ọgwụ na homonụ nwoke, Fluoxetine, Fenfluramine, Ifosfamide, sulfonamides, Amphetamine na tetetamine.
- Nchikota ya na GCS, ogwu diuretic, corticotropin, Danazole, glucagon, homonu (estrogens, gestagens), sympathomimetics, ihe di na thyroid, ihe ndi anakpo phenothiazine, barbiturates na ufodu ogwu ndi ozo na -ebilata hypoglycemic mmetụta nke insulin.
- Mgbe ejikọtara ya na BAB, Clonidine, nnu nke lithium, ihe Insuman Bazal agaghị ekwe omume ịkọ: mmetụta hypo- ma ọ bụ hyperglycemic nwere ike ịmalite.
- Ethanol na-eme na nhazi insulin ahụ enweghị atụghị atụ: nsonaazụ nke Insuman nwere ike ịbawanye ma ọ bụ belata. Ekwesịrị iburu n'uche na ọ bụrụ na agbada ọkwa nke ọrịa glycemia nke onye ọrịa, mgbe ahụ n'okpuru nduzi nke mmanya ma ọ bụ ọgwụ nwere mmanya, ọkwa ya nwere ike ịdaba na ọkwa dị oke egwu, nke nwere ike ibute ahụike na ndụ nke ndị ọrịa mamịrị.
Nsonaazụ
N'oge ị ofụ ọgwụ ọjọọ, ọ dị mkpa iburu n'uche na insulin Bazal nwere ike ịkpasu ọnọdụ ọjọọ na ndị ọrịa mamịrị.
Nsonaazụ kachasị emetụta ya na ọgwụ insulin. Ọ na - etolite mgbe etinyere ọ̀gị nke ọtụtụ oge dị elu karịa mkpa anụ ahụ insulin. Ugboro ugboro ugboro nke ọkwa glucose na-enye aka na mmepe nke nsogbu akwara ozi, nke nwere ike ibute ya na nkwarụ, coma. Ogologo oge na ọgụ siri ike nwere ike kpasu ọnwụ nke onye ọrịa.
Ọ bụrụ nbelata mgbanye glucose emeela nke ukwuu, nke a nwere ike bute hypokalemia nsogbu nke CVS na / ma ọ bụ ụbụrụ.
Na mgbakwunye na hypoglycemia, ndị ọrịa mamịrị nwekwara mmetụta ndị ọzọ na-adịghị mma, gosipụtara n'ụdị mmebi nke akụkụ ahụ na sistem:
- Ihe nrịba ama: anafilaisis, mmeghachi ahụ anụ ahụ, edere nke Quincke, bronchospasm, nguzobe mmadụ (ana - achọ mgbanwe mgbanwe insulin).
- CCC: dobe n'ọbara.
- Filiks metabolism: edema, sodium gabigara n’ahụ.
- Organs nke ọhụụ: nkwarụ ọhụhụ ugboro ugboro, mkpụmkpụ mkpụmkpụ nke retinopathy, mmebi nke akwara ma ọ bụ retina, nke ikpu ìsì nwa oge ma ọ bụ nke na-adịgide adịgide.
- Akpụkpọ anụ na akpụkpọ anụ: lipodystrophy (yana injections mgbe niile n'otu ebe), n'ihi nke a - mmịnye insulin.
- Ọrịa ndị ọzọ: ọbara-ọbara na ebe ntụtụ, itching, ọnya, urticaria, ọria ma ọ bụ ọzịza, ọnya afọ.