Augmentin, mbadamba 625 mg, pcs 14. > Ọgwụgwọ na mgbochi

Biko, tupu ịzụta Augmentin, mbadamba 625 mg, pcs 14,. Lelee ozi banyere ya yana ozi dị na weebụsaịtị webụsaịtị nke onye na-emepụta ma ọ bụ kọwaa nkọwapụta nke otu ụdị na onye njikwa ụlọ ọrụ anyị!

Ozi a gosiputara na saịtị ahụ abụghị onyinye ọha. Onye rụpụtara ya nwere ikike ịme mgbanwe n ’okike, imewe na ịkwakọ ngwaahịa. Ihe osise ngwaahịa na foto nke ewepụtara na katalọgụ saịtị ahụ nwere ike ịdị iche na mbido mbụ.

Ozi banyere ọnụahịa nke egosiri na katalọgụ saịtị ahụ nwere ike ịdị iche na nke dị n'oge ahụ na-etinye iwu maka ngwaahịa kwekọrọ.

Emeputa

Ihe ndị na-arụ ọrụ: amoxicillin (n'ụdị trihydrate) - 875 mg, clavulanic acid (n'ụdị nnu nnu) - 125 mg.

Ndị na-ahụ maka ihe: sterete magnesium - 14.5 mg, sodium carboxymethyl stachi - 29 mg, colloidal silicon dioxide - 10 mg, microcrystalline cellulose - 396.5 mg.

Ngwakọta nke akpụkpọ ahụ ihe nkiri: titanium dioxide - 13.76 mg, hypromellose (5 cps) - 10.56 mg, hypromellose (15 cps) - 3.52 mg, macrogol 4000 - 2.08 mg, macrogol 6000 - 2.08 mg, dimethicone - 0.013 mg.

Omume ọgwụ

Augmentin bụ ọgwụ nje na-egbu egbu, nke na - egbochi nje.

Amoxicillin bụ ọgwụ mgbochi ọgwụ nke na-eme ka mmiri dị nro dị n'ọtụtụ ọgụ na -emegide ọtụtụ gram-positive na gram-microorganisms. N'otu oge ahụ, amoxicillin nwere ike ibute mbibi site na beta-lactamases, yabụ kwa ụdị ọrụ nke amoxicillin anaghị agbasa na microorganisms nke na-emepụta enzyme a.

Clavulanic acid, ihe dị na beta-lactamase inhibitor n'ihe metụtara penisilini, nwere ike ịhapụ ịgbatị ọtụtụ beta-lactamases ndị a hụrụ na penisilini na cephalosporin na-eguzogide ọgwụ. Clavulanic acid na-arụ ọrụ nke ọma megide plasmid beta-lactamases, nke na-abụkarị maka nje na-eguzogide ọgwụ, ọ nweghịkwa arụ ọrụ megide chromosomal beta-lactamases nke ụdị nke 1st, nke clavulanic acid na-egbochi.

Ọnụnọ nke clavulanic acid dị na nkwadebe Augmentin protects na-echebe amoxicillin site na mbibi site na enzymes - beta-lactamases, nke na-enye ohere ịgbasa ụdị nje antibacterial nke amoxicillin.

Ihe ndị a bụ ọrụ njikọta nke vitro nke amoxicillin na clavulanic acid.

Nje bacteria na-agbakarị ọgwụ ma ọ bụ ngwakọta nke amoxicillin na clavulanic acid

Aerobes dị mma: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus spp., Incl. Streptococcus pyogenes 1,2, Streptococcus agalactiae 1,2 (beta beta hemolytic streptococci) 1,2, Staphylococcus aureus (nwere mmetụta nke methicillin) 1, staphylococcus saprophyticus (na-emetụta methicillin), coagulase-negative staphylococci (na-emetụta ya).

Anaerobes dị mma nke Gram: Clostridium spp., Peptococcus niger, Peptostreptococcus spp., Gụnyere Peptostreptococcus magnus, Peptostreptococcus micros.

Gram-negative aerobes: Bordetella pertussis, Haemophilus influenzae 1, Helicobacter pylori, Moraxella cafarrhalis 1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.

Anaerobes ihe na-adịghị mma: Bacteroides spp., Inc. Bacteroides fragilis, Capnocytophaga spp., Eikenella corrodens, Fusobacterium spp., Gụnyere Fusobacterium nucleatum, Porphyromonas spp., Prevotella spp.

Ndị ọzọ: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.

Nje nke bu nje nke nwetara ihe ojoo na nchikota amoxicillin na clavulanic acid nwere ike idi

Aerobes na-adịghị mma: Escherichia coli 1, Klebsiella spp., Incl. Klebsiella oxytoca, Klebsiella poniaoniae 1, Proteus spp., Gụnyere Proteus mirabilis, Proteus vulgaris, Salmonella spp., Shigella spp.

Aerobes dị mma: Gramoria nke Corynebacterium spp., Enterococcus faestero, prọonia, Streptococcus 1,2, nje Virpto nke streptococcus.

Nje bacteria na -eche na -echeta njikọta nke amoxicillin na clavulanic acid

Aerobes Gram-negative: Acinetobacter spp., Citrobacter freundii, Enterobacter spp., Hafnia alvei, Legionella pneumophila, Morganella morganii, Providencia spp., Pseudomonas spp., Serratia spp., Stenotrophomonas maltophilia, Yersin

Ndị ọzọ: Chlamydia spp., Incl. Chlamydia pneumoniae, Chlamydia psittaci, Coxiella burnetii, Mycoplasma spp.

1 Maka ụmụ nje ndị a, a gosipụtara arụmọrụ ọgwụgwọ nke amoxicillin na clavulanic acid na ọmụmụ ụlọ ọgwụ.

2 Usoro nje nke ụdị nje a anaghị arụpụta beta-lactamase. Ihe mmetụta uche na amoxicillin monotherapy na-atụ aro uche yiri nke a na njikọta nke amoxicillin na clavulanic acid.

Ngwakọta ọrụ niile dị na nkwadebe Augmentin - - amoxicillin na clavulanic acid - na - agbakarị ngwa ngwa site na eriri afọ mgbe nchịkwa ọnụ gasịrị. Ntinye nke ihe aru oru n’ime ogwu Augmentin ® di ezigbo nma ma oburu ị takingụ ogwu n’oge mbido nri.

E gosipụtara usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid na ọmụmụ dị iche iche n'okpuru, mgbe ndị ọrụ afọ ofufo ahụike dị afọ 2-12 na afọ na-adịghị mma were 40 mg + 10 mg / kg / ụbọchị nke ọgwụ Augmentin ® na usoro atọ, ntụ ntụ maka nkwụsị ọnụ, Mg mg + 31,25 na 5 ml (156.25 mg).

E gosipụtara nchikota nke amoxicillin na clavulanic acid maka ọgwụgwọ nke nje na-efe efe nke ọnọdụ ndị na-esonụ nke microorganisms nwere mmetụta na nchikota nke amoxicillin na clavulanic acid:

ọrịa dị elu akụkụ okuku ume (gụnyere ọrịa ENT), dị ka ọrịa ụkwara ume ọkụ ugboro ugboro, sinusitis, otitis media, nke na-ebutekarịkarị Streptococcus pneumoniae, Haemophilus influenzae 1, Moraxella catarrhalis 1 na plogenes nkeptoptocccus, (ma e wezụga Augmentin 250 mg / 125 mg mbadamba),
Ọrịa dị ala nke akụkụ okuku ume na akwara, dị ka ihe mgbu nke bronchitis na-adịghị ala ala, ọnya ọgbụgbọ na lobar na bronchopneumonia, na-akpatakarị ọrịa akpịrị gbara ume na Ahụja, Hemophilus influenzae 1 na Moraxella catarrhalis 1,
Ọrịa urinary na-efe efe, dịka ọmụmaatụ, cystitis, urethritis, pyelonephritis, ọrịa nke ụmụ nwanyị, na-ebutekarị site na ụdị nke ezinụlọ Enterobacteriaceae 1 (ọkachasị Escherichia coli 1), ụdị staphylococcus saprophyticus na Enterococcus, yana gonorrhea nke Neisseria gonorrhoeae 1,
Ọrịa akpịrị na anụ ahụ dị nro, nke a na-ebutekarị site na staphylococcus aureus 1, Streptococcus pyogenes na ụdị mkpụrụ ndụ ihe nketa Bacteroides 1,
Ọrịa ọgbụgba na nkwonkwo, dịka ọmụmaatụ osteomyelitis, nke staphylococcus aureus na-akpatakarị 1, ọ bụrụ na ọ dị mkpa, o kwere mee, ogologo oge ọ ga-ekwe omume.
ọrịa odontogenic, dịka ọmụmaatụ periodontitis, odontogenic maxillary sinusitis, ọnya ezé siri ike na mgbasa cellulite (naanị maka mkpụrụ osisi Augmentin, ọnụọgụ 500 mg / 125 mg, 875 mg / 125 mg),
ọrịa ndị ọzọ jikọtara ọnụ (dịka ọmụmaatụ, afọ ime septic, postpartum sepsis, serais intraabdominal) dị ka akụkụ nke usoro ọgwụgwọ (naanị maka mbadamba Augmentin usoro onodu ogwu 250 mg / 125 mg, 500 mg / 125 mg, 875 mg / 125 mg),

Ime na lactation

N'ime omumu banyere oru omumu na anumanu, onu na ochichi nke Augmentin® emeghi teratogenic.

N'ime otu nnyocha ụmụ nwanyị nwere membranes akatabeghị aka, achọpụtara na ọgwụ ọgwụ prophylactic nwere ike ịnwe n'ihe egwu dịkwuo elu nke necrotizing enterocolitis n'ime ụmụ amụrụ ọhụrụ. Dị ka ọgwụ niile, a naghị atụ aro Augmentin® maka oge a dị ime, belụsọ na uru nne elere anya nne ga-akacha n'ihe nwa ebu n’afọ.

Enwere ike iji ọgwụ Augmentin® mee ihe n’oge a na-enye nwa ara. Ewezuga nke enwere ike ịmalite afọ ọsịsa ma ọ bụ candidiasis nke akpụkpọ ahụ mucous nke oghere a na-ejikọta ya na ntinye ọnya ọnya nke ọgwụ a n'ime mmiri ara, ọ nweghị mmetụta ọjọọ ndị ọzọ hụrụ na ụmụ a na-enye ụmụ ara. N'ọnọdụ mmetụta ọjọọ na ụmụaka ndị na-enye nwa ara, ọ dị mkpa ịkwụsị ị breastụ ara.

Nsonaazụ

Ọrịa na nje mgbe mgbe - candidiasis nke akpụkpọ ahụ na akpụkpọ ahụ mucous.

N'akụkụ ọbara na sistem lymphatic: adịkarịghị, enwere ike leukopenia (gụnyere neutropenia) na thrombocytopenia na-agbanwe agbanwe, ọ na-adịkarị ala, na-atụgharị agranulocytosis na mgbake hemolytic, ịgbatị oge prothrombin na oge ọbara ọgbụgba, anaemia, eosinophilia, thrombocytosis.

Si dịghịzi usoro: ọ dịkarịsịrị ike - angioedema, mmeghachi omume anaphylactic, ọrịa nke metụtara ọrịa ọbara, vasculitis nfụkasị.

Si ụjọ usoro: ugboro ugboro - ọgbụgbọ, isi ọwụwa, obere adịkarịghị - mgbanwe mgbanwe hyperactivity, nkwonkwo (nkwarụ nwere ike ịdakwasị ndị ọrịa nwere ọrụ mkpo ya, yana ndị na-anata oke ọgwụ ahụ), nsogbu ehighị ụra, oke iwe, nchekasị, mgbanwe omume.

Site na ngwara: ndi okenye: Ọtụtụ mgbe - afọ ọsịsa, mgbe mgbe - ọgbụgbọ, ọgbụgbọ, ụmụaka - mgbe - afọ ọsịsa, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, dum onu: ọgbụgbọ na-hụrụ mgbe mgbe na-elu doses nke ọgwụ. Ọ bụrụ na mgbe ịmalite ị theụ ọgwụ ahụ enwere mmeghachi omume na-adịghị mma site na eriri afọ, a ga-ewepụ ha ma ọ bụrụ na ị theụọ ọgwụ ahụ na mbido nri. Na - adịghị ala ala - ọgba aghara nri, ọ na - esikarị - mgbochi ọnya nje na - akpata ya site na ị antibioticsụ ọgwụ nje (gụnyere pseudomembranous colitis na hemorrhagic colitis), edere ntutu "nwere ntutu", gastritis, stomatitis. N’aka ụmụaka, mgbe etinyere nkwusioru ahụ, ọ na-abụkarị nke na-achọpụta ịchọpụta elu ala nke enamel ezé. Ileba anya n’uche na-eme ka mmiri ghara ịdị n ’ịchafụ nke ezé, ebe ọ bụ ihe ezuru ịkachapụ ezé gị.

N'akuku nke imeju na akwara biliary: na - adịghị ala ala - mmụba dị ala na ACT na / ma ọ bụ ọrụ ALT (nke a hụrụ na ndị ọrịa na - anata ọgwụgwọ ọgwụ beta-lactam, mana amabeghị mkpa ọria ya), ọrịa ịba ọcha n'anya na cholestatic jaundice (ihe ịtụnanya ndị a kwuru n'oge ọgwụgwọ na penicillins na cephalosporins ndị ọzọ), mmụba na mkpokọta nke bilirubin na alkaline phosphatase. Achọpụtara mmetụta ọjọọ site na imeju bụ ndị ikom na ndị okenye ọrịa nwere ike jikọta ya na ogologo oge ọgwụgwọ. Ọ bụghị obere ụmụaka ka a hụrụ ihe ọjọọ ndị a.

Ihe iriba ama na akara a edepụtara na - emekarị ma ọ bụ ozugbo ngwụcha ọgwụgwọ ahụ, na agbanyeghị, enwere ike ha apụta ọtụtụ izu mgbe emechara ọgwụgwọ ahụ. A na - agbanwegharị ihe ọghọm. Ihe ojoo sitere na imeju nwere ike bụrụ ihe siri ike, n'ọnọdụ ndị a na-adịghị ahụkebe, enwere akụkọ banyere nsonaazụ na-egbu egbu. N'ihe fọrọ nke nta ka ọ bụrụ n'ọnọdụ niile, ndị a bụ ndị nwere nnukwu ọnụọgụ na-arịa ọrịa ma ọ bụ ndị na-enweta ọgwụ nwere ike ịba ama n'otu oge.

Na akpụkpọ anụ ahụ ugboro ugboro - ọnya, pruritus, urticaria, erythema multiforme, adịkarịghị Stevens-Johnson syndrome, necrolysis na-egbu egbu, dermatitis na-egbu egbu, nnukwu exanthematous pustulosis.

N'ọnọdụ mmeghachi omume nfụkasị anụ ahụ, a ga-akwụsị ịhapụ ọgwụgwọ na Augmentin®.

Site na akụrụ na eriri afọ: dịkarịsịrị ala - nephritis interstitial, crystalluria, hematuria.

Mmekorita

A naghị akwado iji otu ọgwụ ọgwụ Augmentin® na probenecid n'otu oge. Probenecid na-ebelata mmiri mmiri nke tubular nke amoxicillin, yabụ, ojiji nke Augmentin® na probenecid nwere ike ibute mmụba nke ọbara na ịnọgidesi ike nke amoxicillin, mana ọ bụghị clavulanic acid.

Ojiji allopurinol na amoxicillin nwere ike ime ka ihe nwetakwuo mmetuta akpụkpọ ahụ. Ugbu a, enweghi data na akwụkwọ a na-eme n'otu oge nke ngwakọta nke amoxicillin na clavulanic acid na allopurinol. Penicillins nwere ike belata mkpochapụ nke methotrexate site na ahụ site na igbochi ihe nzuzo nke tubular ya, yabụ, ojiji nke Augmentin® na methotrexate nwere ike ịbawanye nsí nke methotrexate.

Dị ka ọgwụ ndị ọzọ na-egbochi nje, Augmentin® nwere ike imetụta microflora eriri afọ, na-eduga n'ịbelata nnabata estrogen site na eriri afọ yana mbelata ịdị irè nke ọgwụ mgbochi ọnụ.

Akwukwo a na akowaputa udiri ihe banyere mmụba nke mba ụwa jikọrọ ọnụ (MHO) na ndị ọrịa yana jikọtara ọnụ nke acenocoumarol ma ọ bụ warfarin na amoxicillin. Ọ bụrụ na ọ dị mkpa, ekwesịrị iji nlezianya nyochaa nchịkwa Augmentin® na ọgwụ anticoagulants, oge prothrombin ma ọ bụ MHO mgbe ị na-edepụta ma ọ bụ na-akwụsị nkwadebe Augmentin®; ịhazigharị usoro anticoagulants maka nchịkwa ọnụ.

Etu ị ga-esi, usoro nchịkwa na usoro onunu ogwu

A na-edobe usoro usoro onunu ogwu n'otu oge dabere na afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji were nke ọma ma belata nsonaazụ ọ bụla enwere ike na sistemụ nri, a na-atụ aro Augmentin® ka ebido n'isi nri.

Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume duziri ọgwụ (na mmalite ọgwụgwọ, parenteral management of the ọgwụ with sochiri transition to oral management).

Ndị okenye na ụmụaka karịrị afọ 12 ma ọ bụ na-eru 40 n'arọ ma ọ bụ karịa

1 mbadamba nkume nke 250 mg / 125 mg ugboro 3 / ụbọchị (maka oria dị nro ruo nfe), ma ọ bụ mbadamba ụrọ 500 nke mg / 125 mg ugboro atọ, ma ọ bụ mbadamba ụrọ nke 875 mg / 125 mg 2 ugboro / ụbọchị, ma ọ bụ 11 ml nke nkwụsị nke 400 mg / 57 mg / 5 ml 2 ugboro / ụbọchị (nke ya na mbadamba 1 nke 875 mg / 125 mg).

Mbadamba 2 nke 250 mg / 125 mg ezughị 1 mbadamba 500 nke 500 mg / 125 mg.

Umuaka site na onwa ato rue afo iri na abuo n’ariri aru ha erughi kilogram 40

Edere ọgwụ ahụ n'ụdị nkwusioru maka nchịkwa ọnụ.

A na-eme ngụkọta oge dabere na afọ na oke ahụ, nke egosipụtara na mg / kg body body / day (ịgbakọ dịka amoxicillin) ma ọ bụ na ml nke nkwusioru.

Otutu nke nkwusioru 125 mg / 31.25 mg na 5 ml - ugboro 3 / ụbọchị kwa awa asatọ

Otutu nke nkwusioru 200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml - 2 ugboro / ụbọchị kwa awa 12 ọ bụla.

Usoro usoro usoro ọgwụgwọ a na-atụ aro ya na oge nlekọta ya ka apụtara n'okpuru:

Otutu ntinye - ugboro atọ / ụbọchị, nkwusioru 4: 1 (125 mg / 31.25 mg na 5 ml):

Doses dị ala - 20 mg / kg / ụbọchị.
Ogwu dị ukwuu - 40 mg / kg / ụbọchị.

Otutu nchịkwa - ugboro abụọ / ụbọchị, nkwusioru 7: 1 (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml):

Doses dị ala - 25 mg / kg / ụbọchị.
Doses dị elu - 45 mg / kg / ụbọchị.

A na-eji ọgwụ dị ala nke Augmentin® mee ihe iji gwọọ ọrịa nke anụ ahụ na anụ ahụ dị nro, yana tonsillitis ugboro ugboro.

A na-eji ọgwụ dị elu nke Augmentin® agwọ ọrịa dị ka otitis media, sinusitis, ọrịa nke akụkụ okuku ume na ọnya afọ, ọrịa nke ọkpụkpụ na nkwonkwo.

Enweghi data data ogwu di omimi iji nye aka iji ọgwụ Augmentin® nke ọgwụ jiri ihe kariri 40 mg / kg / ụbọchị n'ime usoro 3 kewara (4: 1 nkwusioru) na ụmụaka na-erubeghị afọ 2.

Umuaka site na omumu rue onwa ato

N'ihi ezumike nke akụrụ ahụ, ọgwụ a tụrụ aro ya nke Augmentin® (ngụkọta maka amoxicillin) bụ mg mg 30 / kg / ụbọchị n'ime usoro 2 nke 4: 1.

Ekwesighi iji nkwusioru 7: 1 (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml) akwadoghị na ọnụ ọgụgụ a.

Umu aka

Enweghị ntuziaka maka usoro usoro usoro onunu ogwu.

Ndị okenye na-arịa ọrịa

Odighi ndozi uzo a choro. N'ime ndị ọrịa nwere nsogbu gbasara akwara nwere nsogbu, ha kwesịrị idozigharị ya dịka ndị a maka ndị okenye nwere ọrụ mgbazi.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu

Imeghari usoro a dabere na oke ọgwụ a tụrụ aro ya na amoxicillin ma a na-eburu n'uche n'uche ụkpụrụ QC.

Mbadamba 250 mg + 125 mg ma ọ bụ 500 mg + 125 mg:

KK> 30 ml / min - a chọghị ndozi nke usoro usoro usoro onunu ogwu.
KK 10-30 ml / min - 1 taabụ. 250 mg + 125 mg ugboro abụọ / ụbọchị ma ọ bụ taabụ 1. 500 mg + 125 mg (maka obere ọrịa na-efe efe ruo obere) 2 oge / ụbọchị.
QC

Nkwụsị 4: 1 (125 mg / 31.25 mg na 5 ml):

KK> 30 ml / min - a chọghị ndozi nke usoro usoro usoro onunu ogwu.
KK 10-30 ml / min - 15 mg / 3.75 mg / n'arọ 2 ugboro / ụbọchị, oke kachasị - 500 mg / 125 mg 2 ugboro / ụbọchị.
QC

Ekwesịrị iji 875 mg + mbadamba mg mg na nkwụsị 7: 1 (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml) naanị na ndị ọrịa nwere CC> 30 ml / min, na-enweghị nhazigharị dose. chọrọ.

N'ọnọdụ ka ukwuu, ọ bụrụ na ọ ga-ekwe omume, a ga-ahọrọ usoro ọgwụgwọ nke ihe na-ahụ maka ọrịa nwa oge.

Ọrịa ịba ọcha n'anya

Nhazi dose dabere na oke ọgwụ a tụrụ aro maka amoxicillin: 2 taabụ. 250 mg / 125 mg n’ime otu ọgwụ kwa awa 24, ma ọ bụ taabụ 1. 500 mg / 125 mg na otu ọgwụ kwa awa 24, ma ọ bụ nkwusioru na 15 mg / 3.75 mg / kg 1 oge / ụbọchị.

Mbadamba ụrọ: n'oge nnọkọ hemodialysis, otu 1 ọzọ (otu mbadamba) na ọgwụ ọzọ (otu mbadamba) na njedebe ngwụcha usoro iji (iji kwụọ ụgwọ maka mbelata nke serum nke amoxicillin na clavulanic acid).

Nkwụsị: tupu oge nnọkọ akwara ụkwụ, otu ọgwụ ọzọ nke 15 mg / 3.75 mg / kg kwesịrị inye. Iji weghachite mkpokọta ihe ndị nọ n'ọrụ ọgwụ ọgwụ Augmentin® n'ọbara, ekwesịrị itinye usoro nke abụọ nke 15 mg / 3.75 mg / kg mgbe emume hapatialysis gasịrị.

Ndị ọrịa nwere ọria imeju

A na- eji nlezianya na-agwọ ọgwụgwọ; a na-enyocha ọrụ imeju. Enweghi data zuru oke iji dozie usoro usoro onunu ogwu di na ndi otu a.

Iwu maka nkwadebe nke nkwusioru

A kwadebere nkwusioru ya ozugbo tupu ojiji izizi.

Nkwusioru (125 mg / 31.25 mg na 5 ml): ihe dị ka 60 ml nke mmiri sie mmiri ga-agbakwunye na ntụ ntụ ntụ, wee mechie karama ahụ na mkpuchi ma maa jijiji ruo mgbe ntụ ntụ kpamkpam, kwere ka karama ahụ kwụrụ ruo minit 5 ruo hụ na ozuzu zuru oke. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 92 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ accurateụ accurateụ ziri ezi, a ga-eji okpu eji atụ ahụ, nke a ga-eji mmiri wee saa ya nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka ụmụaka na-erubeghị afọ abụọ, ịlele otu mmachi maka nkwanye ahụ emezi Augmentin® nwere ike ịgwari ya na ọkara na mmiri.

Nkwusioru (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml): gbakwunye ihe dị ka 40 ml nke mmiri sie mmiri mee ka ọ dị jụụ n'ọnụ ụlọ ahụ na karama ntụ, wee mechie okpu karama ma maa jijiji ruo mgbe ntụ ọka ahụ kpamkpam. Kwe ka vial guzoro na nkeji 5 iji hụ na dilution zuru ezu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 64 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ bụla nke ọma, jiri okpu ị na-eji atụ ma ọ bụ sirinji ọnya, nke a ga-eji mmiri wee saa ahụ nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka ụmụaka na-erubeghị afọ abụọ, a pụrụ iji mmiri tụọ otu ihe na-egbochi nkwusike emepe Augmentin in site na akara 1: 1.

Dodoụbiga ya ókè

Mgbaàmà: mgbaàmà eriri afọ na enweghị mmiri elektrik na - eleghara anya. A kọwara amoxicillin crystalluria, n'ọnọdụ ụfọdụ na-eduga na mmepe nke ọdịda akwara.

Ọnọdụ nwere ike ịdakwasị ndị ọrịa nwere nsogbu gbasara akụrụ, yana ndị na-anata oke ọgwụ.

Ọgwụgwọ: mgbaàmà eriri afọ - ọgwụgwọ ọrịa, na-elezi anya na nhazi nke mmiri mmiri elektrolyte. Bụrụ na ị anụbiga ihe ọseụ ,ụ, enwere ike wepu amoxicillin na clavulanic acid n'ọbara ọbara site na ịba ama.

Nsonaazụ nke ihe ọmụmụ a na-aga n'ihu nke emere ụmụaka 51 n'ime ebe a na-egbu egbu gosiri na nchịkwa nke amoxicillin na nha erughị 250 mg / n'arọ anaghị eduga mgbaàmà dị egwu ma ọ chọghị lavage gastric.

Ntụziaka pụrụ iche

Tupu ịmalite ọgwụgwọ na Augmentin®, ọ dị mkpa ịnakọta akụkọ banyere ahụike zuru ezu gbasara nsogbu hypersensitivity gara aga na penicillins, cephalosporins ma ọ bụ allergens ndị ọzọ.

A kọwara mmeghachi omume dị njọ, na mgbe ụfọdụ ọnwụ, hypersensitivity mmeghachi omume (anaphylactic reactions) na penisilini. Ihe ọghọm nke mmeghachi omume dị otú a bụ nke kachasị elu na ndị ọrịa nwere akụkọ banyere hypersensitivity hypersensitivity penicillins. N'ọnọdụ mmeghachi omume nfụkasị, ọ dị mkpa ịkwụsị ọgwụgwọ na Augmentin® wee malite usoro ọgwụgwọ ọzọ kwesịrị ekwesị. N'ihe banyere nzaghachi hypersensitivity siri ike, e kwesịrị inye epinephrine ozugbo. Oxygen therapy, ochichi nke GCS na inye nke patway ikuku, gụnyere intubation, nwekwara ike choro.

A naghị atụ aro nhọpụta Augmentin® nke ọgwụ n'ọnọdụ ndị a na-enyo enyo na-efe efe monos innosis, ebe ọ bụ na ndị ọrịa nwere ọrịa amoxicillin nwere ike ibute nsị na-efe efe, nke na-agbagha nchọpụta nke ọrịa ahụ.

Ọgwụ ogologo oge na Augmentin® mgbe ụfọdụ na-eduga n'ịmepụta ụmụ irighiri ihe ndị na-adịghị mma.

Na mkpokọta, Augmentin® na-anabata nke ọma ma nwee agwa dị ala nke penisilini niile.

N'oge ọgwụgwọ ogologo oge na Augmentin®, a na-atụ aro ka inyocha akụrụ gbasara akwara, hepatic, na hematopoietic oge.

Iji belata ihe egwu dị na nsị eriri afọ, a ga-a theụ ọgwụ ahụ na mmalite nri.

N'ime ndị ọrịa na-anakọta ngwakọta nke amoxicillin na clavulanic acid yana anticoagulants na-apụtakarị (ọnụ), n'ọnọdụ dị ụkọ, mmụba na oge prothrombin (mmụba na MHO). Site na ntinye njikọta nke anticoagulants na-apụtachaghị ọnụ (ọnụ) yana ngwakọta nke amoxicillin na clavulanic acid, nleba anya nke ihe ndị dị mkpa dị mkpa. Iji nọgide na-enwe mmetụta ọgwụ anticoagulants chọrọ, a pụrụ ịchọ ndozi usoro usoro ọgwụgwọ.

N'ime ndị ọrịa nwere nsogbu gbasara akụrụngwa ezumike, a ga-ebelata ogo Augmentin® otu ọ bụla ha siri metụta ya.

N'ebe ndị ọrịa nwere ọrịa diureis dị ntakịrị, n'ọnọdụ ndị a na-adịghị ahụkebe, a kọpụtara mmepe nke kristal, tumadi site na iji ọgwụ eme ihe. N'oge nchịkwa nke nnukwu ọgwụ nke amoxicillin, a na-atụ aro ka ị ofụọ mmiri zuru ezu ma na-edozi diureis zuru oke iji belata ohere nke ịmepụta kristal amoinillillin.

Iburu ọgwụ Augmentin® n'ime na-eduga n'inwe afọ ojuju nke amoxicillin na mmamịrị, nke nwere ike ibute nsonaazụ ụgha na mkpebi mkpebi nke glucose na mmamịrị (dịka ọmụmaatụ, nnwale Benedict, nnwale na-agba ọkụ). N'okwu a, a na-atụ aro iji usoro glucose oxidant maka ikpebi mkpokọ glucose na mmamịrị.

Ilekọta onụ na-enyere gị aka ịpụpụ ezé, ebe ọ bụ na ichi ezé ezuru gị.

A ga-eji mbadamba mee ihe n'ime ụbọchị iri atọ site na mgbe imepe ngwungwu nke ngwungwu alumọn dị.

Abụbiga ọgwụ ike na ịenceụ ọgwụ

Enweghị ọgwụ ị dependụ ọgwụ, ọgwụ riri ahụ na mmeghachi omume anụ ahụ metụtara iji ọgwụ Augmentin®.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

Ebe ọgwụ ahụ nwere ike ibute ọgbụgba, ọ dị mkpa ịdọ ndị ọrịa aka na ntị banyere ị ga-akpachara anya mgbe ị na-anya ụgbọala ma ọ bụ na-arụ ọrụ igwe na-akpụ akpụ.

Etu esi eji ọgwụ Augmentin 625?

A na-eji ọgwụ mgbochi Semi-sịntetik nke mkpụrụ nke penicillin arụ ọrụ buru ibu Augmentin 625 iji na-agwọ usoro mkpali na ahụ.Ọrịa ndị microorganisms na-enwe banyere amoxicillin na-anabata ọgwụgwọ. A na-eji ọgwụ ahụ emebi ụdị mbuaha nke nje na ụmụ nje na-anọchi anya ya. Organfọdụ mkpụrụ ndụ na - e laomi lactamases, zụlite nguzogide ọgwụ mgbochi Amoxicillin na clavulanic acid na -ebelata nguzogide ha.

Beta-lactams bụ ọgwụ ndị na-egbochi nje ihe maka ojiji nke sistemu ma bụrụ ngwakọta nke ndị na-emebi beta-lactamase na penicillins. Koodu J01C R02.

A na-eji ọgwụ mgbochi Semi-sịntetik nke mkpụrụ nke penicillin arụ ọrụ buru ibu Augmentin 625 iji na-agwọ usoro mkpali na ahụ.

Weputara udi ya na ihe mebere ya

Ọgwụ dị na onunu ogwu 650 (500 mg + 125 mg) dị n'ụdị ọcha ma ọ bụ obere ndò n'ụdị oval. N'elu mpempe akwụkwọ ahụ bụ ihe e dere AC, otu akụkụ bụ notch. A na-akụkọta 7 iberibe na mpempe akwụkwọ, nke a na-akwakọba na igbe mpempe akwụkwọ. Ntụ ntụ dị na vial ahụ adịghị dị ka nkwusioru.

A na-egosi amoxicillin dị ka ihe na-atọ ụtọ, ọ nwere 500 mg,
A na - agbakọta clavulanate na ngụkọta nke 125 mg.

Mlọ ọgwụ

Ihe abụọ a na-agbasi mbọ ike mgbe a na-ewere ya ọnụ, ha bioav adị n'ogo nke 70%. Oge ngosipụta nke ọdịnaya kachasị na plasma ọbara bụ 1 awa. Nleta plasma mgbe ị na-eji ihe jikọtara ọnụ mejupụta Augmentin yiri, ọ bụrụ na a na-ewere amoxicillin na clavulanate iche.

Otu ụzọ n'ụzọ anọ nke ngụkọta nke clavulanate na-edozi na protein, amoxicillin na-ejikọ na 18%. N’ime ahụ, a na-ekesa ihe ndị sitere na:

agntibiotic - 0.31 - 0.41 L kwa kilogram nke ogo ahụ,
acid - 0.21 l kwa kilogram nke uka.

Mgbe nchịkwa gasị, a na-achọpụta ihe abụọ dị na peritoneum, akwa abụba, eriri afọ, ọnya, akwara, ascites na mmiri articular. A na-ahụkarị Amoxicillin n'ime mmiri cerebrospinal, mana ọ na-abanye na mmiri ara nke nwanyị na gafere Plasenta. N’ime anụ ahụ, ihe na ihe ndị ha na-eme anaghị agbakọ.

Amoxicillin na - apụ n'ụdị nke ricinoleic acid na olu nke ụzọ n'ụzọ anọ nke usoro mbụ site na usoro urinary. Clavulanate bụ 75-85% metabolized n'ime ahụ ma hapụ ahụ anụ ahụ yana oke, mmamịrị, ikuku ekuru site na ngụgụ nwere ikuku carbon dioxide.

Ihe ngosi maka ojiji

A na-eji ọgwụ ahụ eme ihe maka ọgwụgwọ ọgwụgwọ na ndị nnọchi anya Augmentin. A na-eji ọgwụ ahụ agwọ ọrịa:

ọnya nke okpukpu mucous nke sinuses, nsogbu na-efe efe mgbe ọsịsị, imi na-agbapụta, ọnya ihu,
mbufụt na etiti ntị
nnukwu ajọ ala ala akwara,
oyi baa na-eto n’èzí ụlọ ọgwụ,
mbufụt nke kaadihe,
mmebi nke sistemụ tubule akụrụngwa,
Ọkpụkpụ mọzụlụ, anụ ahụ na ọrịa akpụkpọ ahụ gbasachara anụmanụ dị iche iche.
mebiri emebi anụ ahụ na akụkụ gbara gburugburu ezé,
Ọkpụkpụ na nkwonkwo.

Mbadamba mbadamba, nke ihe mkpuchi na-acha site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ na-acha ọcha, dị mma, na mbipụta “AUGMENTIN” na-agbanye n'otu akụkụ, na mgbaji, site na-acha ọcha na-acha ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

10 PC. - blisters (1) ya na akpa nke silica gel - ihe eji eme ya na alumini achara (2) - ngwugwu nke kaadiboodu.

Mbadamba mbadamba, nke ihe mkpuchi na-acha site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ na-acha ọcha, dị mma, nwere ihe odide ederede akpọrọ "AC" na ihe egwu dị n'otu akụkụ.

Ndị na - ahụ maka ihe: sterete magnesium - 7.27 mg, sitos steeti sodium carboxymethyl - 21 mg, colloidal silicon dioxide - 10.5 mg, microcrystalline cellulose - ruo 1050 mg.

7 pcs - blisters (1) ya na akpa nke silica gel - ihe eji eme ya na alumini achara (2) - ngwugwu nke kaadiboodu.
10 PC. - blisters (1) ya na akpa nke silica gel - ihe eji eme ya na alumini achara (2) - ngwugwu nke kaadiboodu.

Mbadamba mbadamba, nke ihe mkpuchi na-acha site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha, dị mma, nwere mkpụrụedemede "A" na "C" n'akụkụ mbadamba mbadamba ya na eriri eserese dị n'otu akụkụ, na mgbaji - site na ọcha na-acha odo odo ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

Ndị na-ahụ maka ihe: sterete magnesium - 14.5 mg, sitena sodium carboxymethyl - 29 mg, colloidal silicon dioxide - 10 mg, microcrystalline cellulose - 396.5 mg.

7 pcs - blisters (1) ya na akpa nke silica gel - ihe eji eme ya na alumini achara (2) - ngwugwu nke kaadiboodu.

Ntụ ntụ maka nkwadebe nke nkwusioru maka nchịkwa ọnụ nke ihe na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke na-acha ọcha, nwere njiri mara, mgbe etinyere ya, a na-etisa nkwụchi nke ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke ọcha.

11.5 g - karama karama (1) zuru ezu na okpu eji eme ihe - ngwugwu nke kaadiboodu.

7,7 g - karama karama (1) zuru ezu na okpu eji eme ihe - ngwugwu nke kaadiboodu.

12,6 g - karama karama (1) zuru ezu na okpu eji eme ihe - ngwugwu nke kaadiboodu.

Amoxicillin bụ ọgwụ mgbochi ọgwụ nke na-eme ka mmiri dị nro dị n'ọtụtụ ọgụ na -emegide ọtụtụ gram-positive na gram-microorganisms. N'otu oge ahụ, ọgwụ ce-lactamases ga-emerịrị mbibi ahụ, yabụ na ụdị ọrụ nke amoxicillin anaghị agbasa na microorganisms nke na-emepụta enzyme a.

Clavulanic acid, ihe β-lactamase inhibitor nke metụtara penisilini, nwere ike ime ka ihe dị iche iche β-lactamases ndị dị na penisilini na cephalosporin na-eguzogide ọgwụ.

Clavulanic acid na-arụ ọrụ nke ọma megide s-lactamases plasmid, nke na-ebutekarị nje bacteria, ọ nweghịkwa arụ ọrụ megide chromosomal ct-lactamases nke ụdị 1 nke clavulanic acid na-egbochi.

Ọnụnọ nke clavulanic acid dị na nkwadebe Augmentin na-echebe amoxicillin site na mbibi site na enzymes - β-lactamases, nke na-enye ohere ịmụba ụzarị ọgwụ nje nke amoxicillin.

Ihe ndị a bụ ọrụ njikọta nke vitro nke amoxicillin na clavulanic acid.

Nje bacteria na-agbakarị ọgwụ ma ọ bụ ngwakọta nke amoxicillin na clavulanic acid

Aerobes nke dị mma: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus pyogenes 1,2, Streptococcus agalactiae 1,2, Streptococcus spp. (beta ọzọ hemolytic streptococci) 1,2, Staphylococcus aureus (na-emetụta methicillin) 1, Staphylococcus saprophyticus (na-emetụta methicillin), Staphylococcus spp. (coagulase-adịghị mma, na-emetụta methicillin).

Gram-negative aerobes: Bordetella pertussis, Haemophilus influenzae 1, Helicobacter pylori, Moraxella catarrhalis 1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.

Ndị ọzọ: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.

Anaerobes dị mma nke Gram: Clostridium spp., Peptococcus niger, Peptostreptococcus magnus, Peptostreptococcus micros, Peptostreptococcus spp.

Anaerobes ihe na-acha ọbara ọbara: Bacteroides fragilis, Bacteroides spp., Capnocytophaga spp., Eikenella corrodens, Fusobacterium nucleatum, Fusobacterium spp., Porphyromonas spp., Prevotella spp.

Nje nke bu nje nke nwetara ihe ojoo na nchikota amoxicillin na clavulanic acid nwere ike idi

Aerobes Gram-negative: Escherichia coli 1, Klebsiella oxytoca, Klebsiella pneumoniae 1, Klebsiella spp., Proteus mirabilis, Proteus vulgaris, Proteus spp., Salmonella spp., Shigella spp.

Aerobes dị mma: Corynebacterium spp., Enterococcus faestero, prọonia, Streptococcus 1,2, Virptoans Streptococcus 2.

Nje bacteria na -eche na -echeta njikọta nke amoxicillin na clavulanic acid

Ndị ọzọ: Chlamydia poniaoniae, Chlamydia psittaci, Chlamydia spp., Coxiella burnetti, Mycoplasma spp.

1 - maka ụdị microorganism ndị a, egosipụtara arụmọrụ nke akwara nke nchịkọta nke amoxicillin na clavulanic acid n'ọmụmụ nyocha.

2 - ụdị nke ụdị nje ndị a adịghị emepụta β-lactamases. Ihe mmetụta uche na amoxicillin monotherapy na-atụ aro uche yiri nke a na njikọta nke amoxicillin na clavulanic acid.

Ngwa ọrụ abụọ siri ike nke ọgwụ Augmentin, amoxicillin na clavulanic acid, na-agbakarị ngwa ngwa na ngụkọta afọ na-agafe agafe mgbe nchịkwa ọnụ gasịrị. Mwepu nke ihe ndi ahu di nma kachasi nma ma oburu ị takinguru ogwu na mmalite nri.

Mbadamba Augmentin 250 mg / 125 mg (375 mg), Augmentin 250 mg / 125 mg (375 mg), Augmentin 500 mg / 125 mg (625 mg), Augmentin 875 mg / 125 mg (1000 mg)

A na-egosi usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid, nke a nwetara n'ọmụmụ akwụkwọ dị iche iche, mgbe ndị ọrụ afọ ofufo nwere ahụike mere afọ na-enweghị afọ, ka egosiri n'okpuru:

- 1 mbadamba ọgwụ ọgwụ Augmentin 250 mg / 125 mg (375 mg),

- 2 mbadamba ọgwụ ọgwụ Augmentin 250 mg / 125 mg (375 mg),

- 1 mbadamba ọgwụ ọgwụ Augmentin 500 mg / 125 mg (625 mg),

- 500 mg nke amoxicillin,

- 125 mg nke clavulanic acid,

- 2 mbadamba ọgwụ ọgwụ Augmentin 875 mg / 125 mg (1000 mg)

A na-edobe usoro ọgwụ ọgwụ bụ isi na tebụl.

Mgbe ị na-eji Augmentin, ihe ndị mejupụtara plasma nke amoxicillin yiri nke ndị na-ahụ maka nchịkwa ọnụ nke amoxicillin na usoro nke ya.

Augmentin 125 mg / 31.25 mg kwa ntụ ntụ nkwupụta 5 ml

E gosipụtara usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid na ọmụmụ dị iche iche n'okpuru, mgbe ndị ọrụ afọ ofufo ahụike dị afọ 2-12 afọ na afọ efu weere 40 mg / 10 mg / n'arọ ahụ / ụbọchị nke ọgwụ Augmentin, ntụ ntụ maka nkwụsị ọnụ na ọgwụ 3. 125 mg / 31.25 mg na 5 ml (156.25 mg).

Ihe puru iche nke ọgwụ pharmacokinetic.

Ntụ ntụ maka nkwusioru maka nchịkwa ọnụ Augmentin 200 mg / 28.5 mg na 5 ml

E gosipụtara usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid na ọmụmụ dị iche iche n'okpuru, mgbe ndị ọrụ afọ ofufo ahụike dị afọ 2-12 afọ na afọ efu weere Augmentin, ntụ ntụ maka nkwụsị ọnụ, 200 mg / 28.5 mg na 5 ml (228.5 mg) a dose nke 45 mg / 6.4 mg / kg / ụbọchị, kewara abụọ.

Mpempe ọgwụ pharmacokinetic nke bụ isi

Ntụ ntụ maka nkwusioru maka nchịkwa ọnụ Augmentin 400 mg / 57 mg na 5 ml

E gosipụtara usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid na ọmụmụ dị iche iche n'okpuru, mgbe ndị ọrụ afọ ofufo nwere ahụike were otu ọgwụ Augmentin, ntụ ntụ maka nkwụsị ọnụ, 400 mg / 57 mg na 5 ml (457 mg).

Mpempe ọgwụ pharmacokinetic nke bụ isi

A na -emepụta usoro ọgwụgwọ nke amoxicillin na clavulanic acid na akụkụ ahụ na akwara dị iche iche, mmiri nke na - adị n'etiti akụkụ ahụ, adipose, ọkpụkpụ na akwara, synovial na peritoneal fluid, skin, bile, fluid purulent).

Amoxicillin na clavulanic acid nwere ogo na-esighi ike nke na-ejikọ protein protein. Nnyocha egosila na 25% nke ngụkọta nke clavulanic acid na 18% nke amoxicillin na-egbochi protein protein plasma.

Na omumu ihe omumu, ahutaghi ihe ihe eji eme nri Augmentin.

Amoxicillin, dị ka ọtụtụ penisiliniins, na-abanye n'ime mmiri ara. Achọpụtakwala mpaghara nke clavulanic acid na mmiri ara. Ihe omumu banyere oru omumu n’ime anumanu gosiputara na amoxicillin na clavulanic acid na –ebute ihe mgbochi n’ime ala, n’enweghi ihe ojoo n’enye nsogbu n’aru nwa ebu n’afọ.

10-25% nke ọgwụ mbu nke amoxicillin bụ nke akụrụ na-eme ka ọ bụrụ metabolite na-adịghị arụ ọrụ (penisilloic acid). Clavulanic acid bụ metabolized n'ụba ruo 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid na 1-amino-4-hydroxy-butan-2-otu ma kpụrụ ya na akụrụ site na ngọngọ diges, yana ikuku kubie ume n'ụdị carbon dioxide.

Dị ka ọgwụ penicillins ndị ọzọ, amoxicillin na-apụkarị site na akụrụ, ebe a na-ahụ ọgwụ clavulanic acid site na usoro gbasara akụrụ na extrarenal.Nnyocha e mere egosiwo na, ná nkezi, ihe dị ka 60-70% nke amoxicillin na ihe dị ka 40-65% nke clavulanic acid na-apụ n'anya site na akụrụ na-agbanweghi agbanwe n'ime awa 6 mbụ mgbe ha nwesịrị 1 mbadamba 250 mg / 125 mg ma ọ bụ mbadamba 1 500 nke 500 mg / 125 mg.

Nje virus nke bakteria na-akpata:

Ọrịa nke akụkụ okuku ume na elu akụkụ akụkụ ENT (dịka ọmụmaatụ nro mgbu, sinusitis, otitis media), nke ihe na-ebutekarị bụ Streptococcus pneumoniae, Haemophilus influenzae *, Moraxella catarrhalis *, Streptococcus pyogenes,

- Ọrịa akụkụ okuku ume na-adịghị ala ala: ihe na-akpata ọrịa bronchitis na-adịghị ala ala, ọnya ọgbụgbọ na lobar na bronchopneumonia, nke na-ebutekarịkarị etutoptoptoccus, Haemophilus influenzae * na Moraxella catarrhalis * (ma e wezụga mbadamba 250 mg / 125 mg),

Ọrịa Urogenital traktị: cystitis, urethritis, pyelonephritis, ọrịa nke akụkụ nke akụkụ nke nwanyị, nke na-akpatakarị ụdị mkpụrụ ndụ nke Enterobacteriaceae (nke kachasị Escherichia coli *), staphylococcus saprophyticus na ụdị mkpụrụ ndụ ihe nketa Enterococcus,

- gonorrhoea nke Neisseria gonorrhoeae * kpatara (ma e wezụga mbadamba 250 mg / 125 mg),

- ofufe ọrịa nke anụ ahụ na anụ ahụ dị nro, nke a na-ebutekarị site na Staphylococcus aureus *, Streptococcus pyogenes na ụdị mkpụrụ ndụ ihe nketa Bacteroides *,

- Ọrịa nke ọkpụkpụ na nkwonkwo: osteomyelitis, nke Staphylococcus aureus na - akpata ya, ọ bụrụ na ọ dị mkpa, ogologo oge ọgwụgwọ,

- ọrịa odontogenic, dịka ọmụmaatụ, periodontitis, maxillary sinusitis, ọnya eze siri ike na mgbasa cellulite (maka mbadamba 500 mg / 125 mg ma ọ bụ 875 mg / 125 mg),

- ọrịa ndị ọzọ gwakọtara ọnụ (dịka ọmụmaatụ, afọ ime septic, postpartum sepsis, intra-abdominal sepsis) dịka akụkụ nke usoro ọgwụgwọ (maka mbadamba 250 mg / 125 mg ma ọ bụ 500 mg / 125 mg, ma ọ bụ 875 mg / 125 mg).

* - ndị nnọchite anya nke ụdị microorganisms akọwapụtara na-emepụta β-lactamase, nke na-eme ka ha bụrụ ndị na-enweghị mmetụta na amoxicillin.

Ọrịa Augmentin nwere ike ịgwọ ọrịa ndị nje microorganisms na-emetụta amoxicillin, ebe ọ bụ na amoxicillin bụ otu n'ime ihe ndị dị na ya. Aguputakwara Augmentin maka ọgwụgwọ nke oria ndi na - akpata oria ojoo nke microorganisms na - enwe banyere in-lactamase, nke nwere mmasi nke amoxicillin na clavulanic acid.

Nzuzo nke nje na nchikota nke amoxicillin na clavulanic acid dịgasị dabere na mpaghara na oge. N'ebe enwere ike, ekwesiri iburu n'uche ọgụgụ data mpaghara. Ọ bụrụ na ọ dị mkpa, a ga-anakọta ma nyocha microbiological maka ịchọpụta ihe banyere nje.

- Hypersensitivity na amoxicillin, clavulanic acid, ihe ndị ọzọ dị na ọgwụ ahụ, ọgwụ mgbochi beta-lactam (dịka penicillins, cephalosporins) na anamnesis,

- ihe ndị mere na jaundice gara aga ma ọ bụ ọrụ imeju na - arụ ọrụ mgbe ị na - ejikọkọta amoxicillin na clavulanic acid na anamnesis,

- afọ ụmụaka rue afọ 12 na ịdị arọ nke ihe na-erughị 40 n'arọ (maka mbadamba 250 mg / 125 mg ma ọ bụ 500 mg / 125 mg, ma ọ bụ 875 mg / 125 mg),

- afọ ụmụaka rue ọnwa atọ (maka ntụ ntụ maka ịkwadebe nkwusioru maka nchịkwa ọnụ nke 200 mg / 28.5 mg na 400 mg / 57 mg),

- ọrụ ezigharị adịghị arụ ọrụ (CC ≤ 30 ml / min) - (maka mbadamba 875 mg / 125 mg, maka ntụ ntụ maka nkwusioru maka nchịkwa ọnụ 200 mg / 28.5 mg na 400 mg / 57 mg),

- phenylketonuria (maka ntụ ntụ maka nkwusioru maka nchịkwa ọnụ).

Ihe mgbochi: arụ ọrụ imeju.

A na-edobe usoro usoro onunu ogwu n'otu oge dabere na afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji were mee nke ọma ma belata nsonaazụ ndị enwere ike na sistemụ nri, a na-atụ aro Augmentin ka ebido n'isi nri.

Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume duziri ọgwụ (na mmalite ọgwụgwọ, parenteral management of the ọgwụ with sochiri transition to oral management).

Ndị okenye na ụmụaka karịrị afọ 12 ma ọ bụ na-eru 40 n'arọ ma ọ bụ karịa

Mbadamba 2 nke 250 mg / 125 mg ezughị 1 mbadamba 500 nke 500 mg / 125 mg.

Umuaka site na onwa ato rue afo iri na abuo n’ariri aru ha erughi kilogram 40

Edere ọgwụ ahụ n'ụdị nkwusioru maka nchịkwa ọnụ.

A na-eme ngụkọta oge dabere na afọ na oke ahụ, nke egosipụtara na mg / kg body body / day (ịgbakọ dịka amoxicillin) ma ọ bụ na ml nke nkwusioru.

Otutu nke iwere ihe na-anakpo 125 mg / 31.25 mg na 5 ml bụ ugboro 3 / ụbọchị kwa awa asatọ.

Otutu nke nkwusioru 200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml - 2 ugboro / ụbọchị kwa awa 12 ọ bụla.

Usoro usoro usoro onunu ogwu a ka akwadoro ka ana egosiputa ya na oge oru ya na tebulu di n'okpuru.

Esementia usoro onunu ogwu Augmentin.

A na-eji ọgwụ Augmentin dị ala na-agwọ ọrịa nke anụ ahụ na anụ ahụ dị nro, yana ọrịa otill na-eme ugboro ugboro.

A na-eji ọgwụ Augmentin dị elu na-agwọ ọrịa dịka otitis media, sinusitis, ọrịa nke akụkụ okuku ume na ọnya urinary, ọrịa nke ọkpụkpụ na nkwonkwo.

Enweghi data data nke ulo ogwu ikwuputa iji Augmentin nke ogwu mee ihe na nari ihe kariri 40 mg / kg / day na usoro onwa ato (4: 1 nkwusi) na umuaka noo n’agbata afọ 2.

Umuaka site na omumu rue onwa ato

N'ihi ezumike nke akụrụngwa akụrụ, ọgwụ a tụrụ aro ya na Augmentin (gbakọọ dịka amoxicillin) bụ 30 mg / kg / ụbọchị na usoro ọgwụgwọ abụọ kewara n'ụdị mmachi 4: 1.

Ekwesighi iji nkwusioru 7: 1 (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml) akwadoghị na ọnụ ọgụgụ a.

Umu aka

Enweghị ntuziaka maka usoro usoro usoro onunu ogwu.

Ndị okenye na-arịa ọrịa

Odighi ndozi uzo a choro. N'ime ndị ọrịa nwere nsogbu gbasara akwara nwere nsogbu, ha kwesịrị idozigharị ya dịka ndị a maka ndị okenye nwere ọrụ mgbazi.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu

Imeghari usoro a dabere na oke ọgwụ a tụrụ aro ya na amoxicillin ma a na-eburu n'uche n'uche ụkpụrụ QC.

N'ọnọdụ ka ukwuu, ọ bụrụ na ọ ga-ekwe omume, a ga-ahọrọ usoro ọgwụgwọ nke ihe na-ahụ maka ọrịa nwa oge.

Ọrịa ịba ọcha n'anya

Nkwụsị: tupu oge nnọkọ akwara ụkwụ, otu ọgwụ ọzọ nke 15 mg / 3.75 mg / kg kwesịrị inye. Iji weghachi nchịkọta nke ihe ndị dị n'ọrụ nke Augmentin ọgwụ n'ime ọbara, a ga-enyerịị usoro nke abụọ nke 15 mg / 3.75 mg / kg mgbe emume hapatialysis gasịrị.

Ndị ọrịa nwere ọria imeju

A na- eji nlezianya na-agwọ ọgwụgwọ; a na-enyocha ọrụ imeju. Enweghi data zuru oke iji dozie usoro usoro onunu ogwu di na ndi otu a.

Iwu maka nkwadebe nke nkwusioru

A kwadebere nkwusioru ya ozugbo tupu ojiji izizi.

Nkwusioru (125 mg / 31.25 mg na 5 ml): ihe dị ka 60 ml nke mmiri sie mmiri ga-agbakwunye na ntụ ntụ ntụ, wee mechie karama ahụ na mkpuchi ma maa jijiji ruo mgbe ntụ ọka ahụ kpamkpam, kwe ka karama ahụ guzoro maka 5 nkeji iji hụ na ọ zuru ezu. ozuzu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 92 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ accurateụ accurateụ ziri ezi, a ga-eji okpu eji atụ ahụ, nke a ga-eji mmiri wee saa ya nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka ụmụaka na-erubeghị afọ abụọ, a pụrụ iji otu mmiri tụọ nkwụchi nke ọgwụ Augmentin ga-agbari ya na ọkara.

Nkwusioru (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml): gbakwunye ihe dị ka 40 ml nke mmiri sie mmiri mee ka mmiri ahụ banye na karama ntụ, wee mechie karama ahụ na mkpuchi ma maa jijiji ruo mgbe ntụ ọka ahụ gbazere kpamkpam, nye ya. kwusi vial ahụ maka minit 5 iji hụ na ngwakọta zuru ezu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 64 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ bụla nke ọma, jiri okpu ị na-eji atụ ma ọ bụ sirinji ọnya, nke a ga-eji mmiri wee saa ahụ nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka umuaka n’agbata afo abuo, ihe omuma nke ntughari ogwu Augmentin nwere ike were mmiri jua 1: 1.

Edeputara ihe ojoo ndi a dị n’okpuru dị ka mmebi nke akụkụ ahụ na akụrụngwa na ugboro ole nke ihe omume. A na-ekpebi ugboro ole ọ ga-ewere dị ka ndị a: ọtụtụ mgbe (≥1 / 10), ọtụtụ mgbe (≥1 / 100, 30 ml / min

Augmentin 625 - ọgwụgwọ dị mma maka ọrịa prostatitis

N'ime usoro ọgwụgwọ nke ọtụtụ ọrịa na-efe efe na-emetụta ndị okenye na ụmụaka, a na-eji ọgwụ Augmentin (aha ahia ọzọ bụ Amoxiclav). N'ihi ịdị elu ya, ọgwụ ndị dọkịta na-edekarị ya. Ihe ndị na-arụ ọrụ nke ọgwụ nje jikọtara na-ebibi nje pathogenic, na-egbochi njikọ nke mgbidi nke mkpụrụ ndụ ha.

Koodu nke nhazi ihe ogugu ndi di na ogwu: J01CR02.

Ihe ndị na-arụ ọrụ nke ọgwụ Agmentin jikọtara na-emebi nje nje, na-egbochi njikọ nke mkpụrụ ndụ ha.

2 Ngwakọta na usoro onunu ogwu

Augmentin na - ejikọta ihe ndị na - arụ ọrụ 2: amoxicillin (Amoxicillin) na clavulanic acid (clavulanic acid). Amoxicillin dị na ndepụta ọgwụ ndị dị mkpa nke WHO mere.

Releasedị nke ịhapụ ọgwụ mgbochi:

Mbadamba Augmentin 375 mg, 625 mg na 1000 mg,
ntụ ntụ maka ịgbaze, nke esite na nkwusioru maka nchịkwa ọnụ ma ọ bụ ihe ngwọta maka ntụtụ (naanị intravenous).

Otu mbadamba 1 nke Augmentin 625 nwere 500 mg nke amoxicillin trihydrate na 125 mg nke clavulanate potassium.

onyinye stachi na sodium,
sịlịkọn dioxide
stereta magnesium,
microcrystalline cellulose.

Augmentin dị n'ụdị ntụ ntụ maka nrụzigharị, site na nke a kwadebere nkwụsị maka nchịkwa ọnụ.

Mbadamba ahụ nwere ihe ngosi nke ihe nkiri, nke gụnyere:

ọgwụ mgbochi (polymer),
dimethicone (silicone),
titanium dioxide (ncha ọcha),
macrogol (laxative).

Na-eburu Augmentin 625: 7 ma ọ bụ mpempe 10 na aluminom foil, 1 ma ọ bụ blisters abụọ na igbe kaadi nwere ntinye aka na ntuziaka silica.

6 Uzo esi ewere Augmentin 625

Iji mee ka ọgwụ gị dịkwuo mma ma nwee ike inwe mmetụta ndị ọ ga-akacha ntakịrị, onye nrụpụta na-atụ aro iji mbadamba mbido nri. A na-ahọrọ usoro onunu ogwu na-eburu n'uche ụdị, ọrịa nke ọrịa, afọ, ibu na ọnọdụ akụrụ onye ọrịa. Ọ bụ na usoro nke Augmentin dị ntakịrị ka enyere n'iwu maka ọrịa ọnya anụ ahụ dị nro, anụ ahụ, tonsillitis na nlọghachi ugboro ugboro. A chọrọ oke onunu ogwu iji gwọọ sinusitis, otitis media, ọrịa nke ngụgụ, pleura, ọkpụkpụ, na usoro urinary.

N'ihe banyere usoro ọgwụgwọ na-agafe agafe, ndị okenye na ụmụaka nọ n'afọ iri na abụọ ka enyere iwu ka ha were mbadamba 1 nke ọgwụ nje 375 mg ugboro atọ n'ụbọchị, n'ọnọdụ dị egwu - 1 mbadamba 625 mg. Okwesiri iburu n’uche na mbadamba 1 nke Augmentin 625 mg erughị 2 mbadamba 375 mg. A na-eme mgbanwe site na usoro ịgba ọgwụ na-eji ọgwụ a na mbadamba ọgwụ.

Maka ụmụaka na-erubeghị afọ iri na abụọ, ọgwụ dị n'ụdị sirop (ọ na-akwadebe site na ntụ ntụ). A na-agbakọ kwa usoro nke ọgwụ nje a na-enye nwata ahụ ugboro atọ n'ụbọchị na-eburu n'uche afọ ya:

Ọnwa 9 - afọ 2: 62.5 mg,
2-7 afọ: 125 mg,
7,12 afọ: 250 mg.

Usoro akwadoro nke 4: 1 nkwusioru maka ụmụaka site na ọnwa 1 ruo atọ bụ mg mg 30 (maka amoxicillin) kwa kilogram 1 nke ịdị arọ, nke enyere na nha 2 kewara. Ọnwụnwa nke ụlọ ọgwụ ezughi oke maka ịkọwapụta usoro nke ihe karịrị 40 mg + 10 mg / kg na usoro 3 kewara maka ụmụaka na-erubeghị afọ abụọ.

Ogologo oge ọgwụgwọ ya na Augmentin sitere na ụbọchị ise ruo ụbọchị iri na anọ.

Mgbe ị na-ahọrọ usoro onunu ogwu, ọ dị mkpa ịtụle ma onye ọrịa ahụ ọ nọ n'ihe egwu. Nke a bụ:

Ndị ọrịa nwere ọrụ mgbazinye nsogbu. A na-atụ aro ka iji ọgwụ mgbochi ọgwụ kacha elu nyere ya iji nyefee ya n'aka ya. A na-enye ọgwụ ọgwụ kacha mma intravenly.
Ndị ọrịa nwere ọrịa imeju. Oge ịlele ọnọdụ nke anụ ahụ dị mkpa.
Ndị okenye. Imezi usoro onunu ogwu adighi nkpa ma oburu na enweghi oria akwara na imeju.
Oria ndi choro ighota ya. Nkwupụta akwadoro: 1 mbadamba Augmentin 625 mg kwa ụbọchị. Agbakwunyere na: tupu usoro a ma emechaa - 1 mbadamba.

Ndị okenye anaghị achọ mmezi usoro ọgwụgwọ ma ọ bụrụ na enweghi ọrịa nke akụrụ na umeji.

7 Ndụmọdụ pụrụ iche

Tupu ịmalite ị antibụ ọgwụ nje, ọ dị mkpa ịchọpụta ma onye ọrịa ahụ enweburu mmeghachi omume nfụkasị penicillins ma ọ bụ cephalosporins. Mmeghe nke anaphylactic ujo di obere. Mgbe amamịghe nke penicillins gosipụtara, ekwesịrị iwepu ọgwụ mgbochi ozugbo. Epinephrine na corticosteroid injections, oxygenation (ngụkọta anụ ahụ nke mkpụrụ ndụ ahụ na oxygen), intubation (ịgbasa trachea ahụ iji weghachi iku ume) na-enyere aka wepu onye ọrịa ahụ n'ọnọdụ ọnọdụ ụjọ.

Site na ntinye aka nke Augmentin na ọgwụ anticoagulant na mbadamba, mgbe ụfọdụ ọ ga-adị mkpa ka iwelie onunu ogwu ha ka ha nweta nsonaazụ a tụrụ anya.

Ogologo oge eji ọgwụ nje, karịchaa, na oke ọnụọgụ, na-ebute mmepe nke dysbiosis, arụ ọrụ nke sistem hematopoietic na akụrụ. Ọ bụrụ na mwepụ creatinine erughị 30 ml / min, naanị Augmentin mbadamba 625 mg na 375 mg, nkwụsị 125 + 31.25 mg, ọgwụ ntụtụ 500 + 100 mg na 1000 + 200 mg na-anabata.

Ọ bụrụ na ị na-enyo enyo mononucleosis nke ọdịdị nje, ịkwesighi ịkọ ọgwụ ahụ, n'ihi amoxicillin na-ebute akpukpo akpukpo aru nke akpịrị. Ọrịa dị otú ahụ nwere ike ịkpalite nchọpụta ụgha.

Mgbe ị na-eji ọgwụ ọgwụ nje buru ibu, a chọrọ ị aụ mmanya dị ukwuu iji zere kristalin nke amoxicillin na mmiri. Nnukwu ọgwụ dị na mmamịrị nwere ike iduga nyocha mmamịrị glucose dị mma. A na-atụ aro ka a rụọ nyocha ụlọ nyocha site na iji usoro glucose oxidant.

Ihe ngosi maka ojiji

Nje virus nke bakteria na-akpata:

Ọrịa nke akụkụ okuku ume na elu akụkụ akụkụ ENT (dịka ọmụmaatụ ụkwara ume ọkụ ugboro ugboro, sinusitis, otitis media), na-ebutekarịkarị akpịrị Streptococcus pneumoniae, ọkụ ọkụ Haemophilus, Moraxella catarrhalis, pulgenesptoptoccccus,
Ọrịa ọgbụgbọ na-adịghị ala ala: ihe na-akpata ọrịa bronchitis na-adịghị ala ala, ọnya ọgbụgbọ na lobar na bronchopneumonia, na-akpatakarị ọrịa akpịrị gbara oyi nke ọrịa kọfịkịtị Haemophilus na Moraxella catarrhalis (ma e wezụga mbadamba 250 mg / 125 mg),
Ọrịa urinary na-efe efe: cystitis, urethritis, pyelonephritis, ọrịa nke akụkụ ahụ nwanyị, nke na-ebutekarị site na ụdị nke ezinụlọ Enterobacteriaceae (ọkachasị nke Escherichia coli *), staphylococcus saprophyticus na ụdị ụdị mkpụrụ ndụ Enterococcus,
gonorrhoea nke Neisseria gonorrhoeae kpatara (ma ọ bụghị mbadamba 250 mg / 125 mg),
Ọria na akpukpo anụ ahụ na anụ ahụ dị nro, nke a na-ebutekarị site na Staphylococcus aureus, Streptococcus pyogenes na ụdị mkpụrụ ndụ ihe nketa Bactero> Usoro ọgwụgwọ na nchịkwa

A na-edobe usoro usoro onunu ogwu n'otu oge dabere na afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji were mee nke ọma ma belata nsonaazụ ndị enwere ike na sistemụ nri, a na-atụ aro Augmentin ka ebido n'isi nri.

Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume duziri ọgwụ (na mmalite ọgwụgwọ, parenteral management of the ọgwụ with sochiri transition to oral management).

Ihe ngbanwe

hypersensitivity na amoxicillin, clavulanic acid, ihe ndị ọzọ dị na ọgwụ ahụ, ọgwụ mgbochi beta-lactam (dịka penicillins, cephalosporins) na anamnesis,
ihe omume gara aga nke jaundice ma ọ bụ ọrụ imeju na-arụ ọrụ mgbe ị na-ejikọkọta ọgwụ amoxicillin na clavulanic acid na akụkọ ntolite.
ụmụaka na-erubeghị afọ 12 na ahụ ha erughị 40 n'arọ

Ọnọdụ nchekwa

Ekwesịrị ịchekwa ọgwụ ahụ ka ụmụaka ghara iru ya na okpomọkụ agaghị agafe 25 Celsius.

Na otu mbadamba onụ nwere 0,25, 0,5 ma ọ bụ 0.875 g amoxicillin trihydrate na 0.125 g acid clavulanic (N'ịmepụta ọgwụ ahụ, a na-etinye sodium clavulanate na ngafe 5%).

Agụnyere na ogwu ihe inyeaka: Silicii dioxydum colloidale, magnesium stearate, Carboxymethylamylum natricum, Cellulosum microcrystallicum.

Otu karama ntụ ntụ maka ịkwadebe ya maka injection nwere 0,5 ma ọ bụ 1 g amoxicillin trihydrate na, n'otu n'otu, 0.1 ma ọ bụ 0.2 g acid clavulanic.

Ihe mejupụtara Augmentin ntụ ntụ maka nkwusioru maka nchịkwa ọnụ gụnyere 0.125 / 0.2 / 0.4 g (5 ml) amoxicillin trihydrate na, n'otu n'otu, 0.03125 / 0.0285 / 0.057 g (5 ml) acid clavulanic.

Ngwa ihe inyeaka: Xanthan gum, Hydroxypropyl methylcellulose, Silicii dioxydum colloidale, Acidum succinicum, silicii dioxydum, Aspartamum (E951), akọrọ - oroma oroma (610271E na 9/027108), raspberry na “Bright molasses”.

Na ntụ ntụ Augmentin EU bu n’obi nkwadebe nke 100 ml nke nkwusiorunwere 0.6 g (5 ml) amoxicillin trihydrate na 0.0429 g (5 ml) acid clavulanic.

Ngwa ihe inyeaka: Silicii dioxydum colloidale, Carboxymethylamylum natricum), Aspartamum (E951), Xanthan gum, Silicii dioxydum, ahihia ahihia 544428.

Na nhazi nke otu Mbadamba ụrọ Augmentin CP na ogologo oge eme ihe gụnyere 1 g amoxicillin trihydrate na 0.0625 g acid clavulanic.

Ngwa ihe inyeaka: Cellulosum microcrystallicum, Carboxymethylamylum natricum, Silicii dioxydum colloidale, Magnesium stearate, Xanthan gum, Acidum citrinosum, Hycromellosum 6cps, Hypromellosum 15cps, Titanium dioxide (E171), Macrogolum 3350, Mac50olum.

Ọgwụ nwere ụdị nnabata ndị a:

Mbadamba Augmentin 250 mg + 125 mg, Augmentin 500 mg + 125 mg na Augmentin 875 + 125 mg.
Powder 500/100 mg na 1000/200 mg, bu n’obi maka nkwadebe nke ihe eji egbu egbu.
Ntụ maka nkwụsị Augmentin 400 mg / 57 mg, 200 mg / 28.5 mg, 125 mg / 31.25 mg.
Ntụ ntụ Augmentin EU 600 mg / 42.9 mg (5 ml) maka nkwusioru.
Augmentin CP 1000 mg / 62.5 mg nwere mbadamba mbugharị ha

Augmentin bụ ndị otu ọgwụ ọgwụ ọgwụ "ọgwụ antimicrobial maka iji usoro. -lactams. Penicillins. ”

Mmetụta ọgwụ ọgwụ dị ọgwụ nje na ọgwụ nje.

Pharmacodynamics na pharmacokinetics

Dika Wikipedia si kwuo, Amoxicillin bu onye nje nje njedị irè megide ọtụtụ pathogenic na enwere ike pathogenic ụmụ nje na nnọchite anya ọgwụ mkpịsị mkpụrụ ọgwụ semisynthetic.

Idochi anya transpeptidase na imeghari usoro nhazi mureina (akụkụ kachasị mkpa nke mgbidi nke mkpụrụ ndụ nje) n'oge nkewa na uto, ọ na-akpasu iwe nyocha (mbibi) nje.

A na-emebi Amoxicillin -lactamasesya mere ihe ogba-ama ya adighi erute ụmụ njena-arụpụta -lactamases.

Na-eme dị ka asọmpi na ọtụtụ ikpe irreversvers inhibitor, acid clavulanic mara na ikike ibanye n’ime mgbidi mgbidi nje ma bute mmerụ ahụ enzymesnke dị ma ime ụlọ ma na nsọtụ ya.

Clavulanate na-etolite ogige ejiri rụọ ọrụ -lactamasesnke a na - egbochi mbibi amoxicillin.

Mkpụrụ ọgwụ Augmentin dị irè megide:

Aerobes (+) ikuku: pyogenic streptococcus otu A na B, pneumococci, Staphylococcus aureus na epidermal, (ewezuga ụdị nsogbu methicillin na-eguzogide), staflococcus saprophytic na ndị ọzọ
Ikuku (-) aerobes: Ogwe osisi Pfeiffer, Ukwara-nta, gardnerella vaginalis , cholera vibrio wdg
Gram (+) na gram (-) nke anaerobes: bacteroid, fusobacteria, preotellas wdg
Ihe microorganisms ndị ọzọ: chlamydia, spirochete, treponema paịlị wdg

Mgbe ogwachara Augmentin, ngwa ọrụ ya abụọ na-agbadata ngwa ngwa ma zuo ezu na ngọngọ nri. Ibepu abacha ihe zuru oke ma oburu na ị were ogwu ma obu sirop mgbe iri nri (na nmalite nri).

Abụọ mgbe e jiri ọnụ mee ya, yana iwebata ihe ngwọta nke Augmentin nke anọ, a na-ahụta usoro ọgwụgwọ nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ na akwara niile na mmiri.

Ngwaọrụ abụọ ahụ na-arụ ọrụ ike na-esighi ike protin ọbara nke plasma (ihe ruru 25% jikọrọ protein protein) amoxicillin trihydrate na ọ dịghị ihe karịrị 18% acid clavulanic) Achọpụtaghị nchịkọta Augmentin na akụkụ ọ bụla dị n'ime.

Amoxicillin kpughere ya metabolization na ahu ma wepuga ya akụrụsite na ngha nke diges na udi nke carbon dioxide tinyere ikuku ekuru. 10 ka 25% nke ọgwụ natara amoxicillin wepụwa akụrụ n'ụdị penisilloic acidnke bu adighi ike metabolite.

Clavulanate site na akụrụ ya na site na usoro ndị ọzọ.

Ihe ngosi maka ojiji

Ihe ngosiputa maka ojiji amoxicillin trihydrate na acid clavulanic bụ na-efe efemkpasu iwe banyere ihe ndia ụmụ nje.

Anabatakwa ọgwụgwọ Augmentin. na-efe efeihe omume rụpụtara ụmụ njenwee mmetụta ọsọ ọsọ na-arụ ọrụ amoxicillinyana agwakọta na-efe efekpasuru ya iwe nje ndị nje amorelere na nje ndị na-emepụta β-lactamase ọ na-eji uche mara ya na ngwakọta nke ọgwụ ọgwụ nọ n'ọrụ.

Na Internetntanetị, a na-ajụkarị ajụjụ “Kedu mkpụrụ mbido Augmentin? "Ma ọ bụ" Gịnị bụ Augmentin Syrup Curing? ".

Okirikiri nke ọgwụ a sara mbara. Edere ya na ihe ndị a ọrịa na-efe efe na mkpali:

na na-efe efena-emetụta elu na ala iku ume ala (gụnyere gụnyere Ọrịa ENT),
na na-efe efena-emetụta ọnya mkpụrụ ndụ,
na odontogenic (onu n’onu) oria,
na ọrịa gynecological,
na ọgbụgba,
na na-efe efena-emetụta anụ ahụ na anụ ahụ dị nro,
na na-efe efena-emetụta anụ ahụ (gụnyere ma ọ bụrụ na ọ dị mkpa, nhọpụta nke onye ọrịa ogologo oge),
ihe ndi ozo na-efe efe ụdị agwakọta (dịka ọmụmaatụ ẹphe tụko iphena sepsis n'oge nke ọmụmụ, na ọrịa mbufụt (sepsis na-enweghị metastases), peritonitisna sepsiskpatara ọrịa intraabdominalna na-efe efena-emepe emepe ihe ogwugwo).

A na-ejikarị Augmentin dị ka ihe mgbochi tupu ịmalite ọrụ ịwa ahụ dị ukwuu na isi, olu, eriri afọ, akụrụ, ọnya biliary, n’elu akụkụ ndị dị na oghere pelvicyana n'oge usoro ịkụbanye akụkụ ahụ dị n’ime.

Augmentin n'ụdị usoro onunu ogwu ka contraindicated:

ndị ọrịa nwere ọgwụ mgbochi otu ma ọ bụ akụkụ abụọ nke ọgwụ ahụ, nye onye ọ bụla n'ime ya, yana -lactam (i.e. to ọgwụ nje site na otu penisilini na cephalosporin),
ndị ọrịa nwetagogola usoro ọgwụgwọ Augmentin jaundice ma ọ bụ akụkọ banyere arụ ọrụ imeju n'ihi ojiji nke ngwakọta nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ.

Mgbakwunye mgbochi ọzọ na nhọpụta ụrọ maka nkwadebe nke nkwusioru ọnụ yana iji ọgwụ nke ihe arụ ọrụ 125 + 31.25 mg bụ PKU (phenylketonuria).

A na-egbochi ntụ ntụ iji kwadebe nkwusioru nke ọnụ na-eji ya eme ihe (200 + 28.5) na (400 + 57) mg:

na PKU,
ndị ọrịa nwere nsogbu akụrụna nke egosi Reberg nwale n'okpuru 30 ml kwa nkeji
ụmụaka na-erubeghị afọ atọ.

Mgbakwunye ọzọ maka iji mbadamba nkume nwere ọgwụ ihe eji eme ihe (250 + 125) na (500 + 125) mg bụ afọ n'okpuru afọ iri na abụọ na / ma ọ bụ ibu na-erughị kilogram 40.

Mbadamba ọgwụ nwere ọgwụ ike 875 + 125 mg na-egbochi ọgwụ:

mebie ọrụ arụmọrụ akụrụ (ndị na-egosi Reberg nwale n'okpuru 30 ml kwa nkeji)
ụmụaka na-erubeghị afọ iri na abụọ
ndị ọrịa nke ịdị arọ ya anaghị agafe 40 n'arọ.

Nsonaazụ nke Augmentin nwere ike ime site na sistemụ na akụkụ mmadụ dị iche iche. Ọtụtụ mgbe, megide ndabere nke ọgwụgwọ ọgwụ, enwere ike ibute mmeghachi omume ndị a:

candidiasis (thrush) akpụkpọ ahụ na akpụkpọ anụ mucous,
afọ ọsịsa (oge niile - mgbe ị na-ewere Augmentin na mbadamba, oge ụfọdụ mgbe ị na -ekwụsịtụ ma ọ bụ na-abanye ọgwụ ahụ),
ọgbụgbọ na ọgbụgbọ (ọgbụgbọ na-abụkarị mgbe ị na-a theụ ọgwụ ahụ na oke doses).

Mmetụta ọghọm ọ na-erite na-enweghị oge ịgụnye:

anya ntughari,
isi ọwụwa,
dysfunctions mgbaze,
mmụba dị nta na ọrụ enzyme imeju omarnine transaminases (ALT) na asmitate transaminases (AST),
akpukpo aru, akpụkpọ anụ?ekpughere urticaria.

N'ọnọdụ ndị a na-adịghị ahụkebe, ahụ nwere ike ịzaghachi nnabata nke Augmentin:

atụgharị leukopenia (gụnyere gụnyere agranulocytosis),
thrombocytopenia,
mmepe thrombophlebitis n’ebe a na-agba ya ọgwụ
polymorphic erythema.

Ọ dịkarịghị ike ịmalite:

hemolytic anaemia,
ọnọdụ e ji mmụba na-egbu oge ọbara ọgbụgba na abawanye ntụpọ prothrombin,
mmeghachi omume sitere na na dịghịzi usoronke egosiri dika angioedema, ọrịa nke yiri nke ahụ gosipụtara ọrịa ọbara, anafilaisis, nfụkasị vasculitis,
hyperactivity ụdị enwere ike ịgbanwe
abawanye ihe omimi,
pricksn'ihi nnabata ọgwụ njegụnyere gụnyere pseudomembranous (PMK) na ọbara ọgbụgba (enwere ike itolite nke ikpe-azụ na-ebelata ma ọ bụrụ na a na-achịkwa Augmentin parenterally),
keratinization na uto nke papillae udi nwere ire (oria akporo 'asusu nwere ntutu'),
ịba ọcha n'anya na cholestasis intrahepatic,
Ọrịa Lyell,
juputara na pustulosis na-ahụ anya n'ụdị siri ike
interstitial nephritis,
Ngosipụta na mmamịrị nke kristal nnu (kristalia).

Bụrụ na nke ọ bụla ọrịa akpịrị A ga-akwụsị ịgwọ ọrịa nfụkasị Ọdụdọ Augmentin.

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Otu n'ime ajụjụ ndị ọrịa na-ajụkarị bụ ajụjụ banyere etu esi ewere ọgwụ tupu ma ọ bụ mgbe nri gasịrị. N'ihe banyere Augmentin, ị theụ ọgwụ ahụ na iri nri. Echere na ọ kacha mma ị optụ ọgwụ ahụ. tupu nri.

Nke mbu, o na - enye nnabata ha nma nma Ọkpụkpụ afọ, na nke abuo, o nwere ike belata oke ihe obula eriri afọ dyspeptikọ bụrụ na nke ikpeazụ bụ ikpe.

Etu ị ga-esi gbakọọ ọgwụ Augmentin

Etu ị ga-esi ewere ọgwụ Augmentin maka ndị okenye na ụmụaka, yana usoro ọgwụgwọ ya, dabere na nke microorganism bụru ẹphe, ẹphe ele ẹnya iya ọgwụ nje, ogo na njiri mara ọrịa ahụ, nsonye nke ọrịa na-efe efe, afọ na ịdị arọ nke onye ọrịa, yana otu ahụ ọ dị akụrụ onye ọrịa.

Oge ọ na-anọ n’ọgwụ na-adabere n’otú ahụ onye ọrịa si emeghachi omume na ọgwụgwọ.

Mbadamba Augmentin: ntuziaka maka ojiji

Dabere na ọdịnaya nke ihe ndị na-arụ ọrụ n'ime ha, a na-atụ aro mbadamba Augmentin maka ndị ọrịa toro etozi dịka atụmatụ na-esote:

Augmentin 375 mg (250 mg + 125 mg) - otu ugboro atọ n'ụbọchị. N'ime usoro ogwu a, a na-egosi ọgwụ ahụ maka na-efe efenke ahụ na-abata mfe ma obu udi aru ike. N'ihe banyere ọrịa siri ike, gụnyere ọrịa na-adịghị ala ala na oge nlọghachi, a na-enye usoro ọgwụgwọ dị elu.
Mbadamba mbadamba 625 (500 mg + 125 mg) - otu ugboro atọ n'ụbọchị.
Mbadamba 1000 mg (875 mg + 125 mg) - otu ugboro abụọ n'ụbọchị.

Ogwu a dabere na ndị ọrịa nwere arụmọrụ arụmọrụ. akụrụ.

A na-anabata Augmentin CP 1000 mg / 62.5 mg mbadamba mbugharị ndị ọrịa maka ndị ọrịa karịrị afọ 16. Ihe kachasị mma bụ mbadamba abụọ ugboro abụọ n'ụbọchị.

Ọ bụrụ na onye ọrịa enweghị ike ilo mbadamba ihe niile, o kewara abụọ na ụzọ adịghị mma. A na-ewere halves abụọ n'otu oge.

Ndi nwere oria akụrụ Ọ bụ ọgwụ ka etinyere naanị ọgwụ ikpe ebe egosi Reberg nwale karịrị 30 ml kwa nkeji (ya bụ, mgbe achọrọghị mmezi usoro usoro usoro onunu ogwu).

Ntụ ntụ maka iji gwọọ ntụtụ: ntuziaka maka ojiji

Dabere na ntuziaka ahụ, a na-agbanye mgbakwunye n'ime akwara: site na jet (a ga-emejupụta ọgwụ niile na nkeji 3-4) ma ọ bụ site na usoro nfe (oge infusion - site na ọkara otu awa ruo nkeji 40). Ebumnuche a abụghị ka etinye ya n’akwara.

Ọkwa ọkọlọtọ maka onye ọrịa okenye bụ 1000 mg / 200 mg. Ọ na-atụ aro ịbanye na ya awa asatọ ọ bụla, yana maka ndị nwere nsogbu na-efe efe - isii n’ime awa isii ma ọ bụ anọ ọ bụla (dịka ihe gosiri).

Ọgwụ nje n'ụdị ihe ngwọta, enyere 500 mg / 100 mg ma ọ bụ 1000 mg / 200 mg maka mgbochi nke mmepe bu oria mgbe ogwachara ya. N'ọnọdụ ebe oge ịwa ahụ na-erughị otu awa, o zuru ezu ịbanye onye ọrịa otu oge tupu ahu izizi dose nke Augmentin 1000 mg / 200 mg.

Ọ bụrụ na echere na arụmọrụ ahụ ga-ewe ihe karịrị otu elekere, ruo ihe onunu anọ nke 1000 mg / 200 mg ka a na-enye onye ọrịa ahụ n’ụbọchị gara aga maka awa 24.

Nkwụsị Augmentin: ntuziaka maka ojiji

Ntụziaka maka iji Augmentin maka ụmụaka na-atụ aro ịhapụ nkwụsị nke ọgwụ mgmg mg / mg mg 25,25 na mmeri nke 2,5 ruo 20 ml. Otutu nnabata - 3 n’ehihie. Olu nke otu uzo dabere n’afọ na ogo nwata.

Ọ bụrụ na nwatakịrị ahụ etoola ọnwa abụọ, etinyere ọgwụ mgbochi nke 200 mg / 28.5 mg n'ọtụtụ nhata 25 / 3.6 mg na 45 / 6.4 mg kwa 1 n'arọ nke ahụ. Ekwesịrị ịkewapụta usoro ahụ ka ọ bụrụ ntụtụ abụọ.

Egosiputara ya na iji usoro onodu ogwu 400 mg / 57 mg (Augmentin 2) gosiputara maka ojiji malite n’afọ. Dabere na afọ nwata na ịdị arọ nwatakịrị ahụ, otu ụzọ dịgasị si 5 na 10 ml. Otutu nnabata - 2 n'ehihie.

E nyere Augmentin EU iwu site na ọnwa atọ. Ogo kachasị mma bụ 90 / 6.4 mg kwa 1 n'arọ nke ịdị ahụ kwa ụbọchị (a ga-ekewa dose ahụ ka ọ bụrụ usoro 2, na-edebe oge awa 12 n'etiti ha).

Taa, ọgwụ n'ụdị usoro dịgasị iche iche bụ otu n'ime ndị akachasị idebere maka ọgwụgwọ. ọnya afọ.

Augmụaka Augmentin nwere akpịrị mgbu Edebere ya na usoro nke kpebisiri ike dabere nha ahụ na afọ nwata ahụ. Na angina n'ime ndị okenye, a na-atụ aro iji Augmentin na 875 + 125 mg ugboro atọ n'ụbọchị.

Ọzọkwa, ha na-ejikarị nhọpụta nke Augmentin sinusitis. A na-agbakwunye ọgwụgwọ a site na iji nnu nnu n'oké osimiri na-ehicha imi na iji spalys nke nasal Rinofluimucil. Usoro kachasị mma maka sinusitis: 875/125 mg 2 ugboro n'ụbọchị. Oge ihe ọmụmụ ahụ na-abụkarị 7 ụbọchị.

Ceedgafe ogo nke Augmentin na-eso:

mmepe nke imebi site na ngwe nri,
imebi nguzo nke nnu-mmiri,
kristalia,
gbasara akwara,
ọdịda (ọdịda) nke amoxicillin na urinary catheter.

Mgbe mgbaàmà ndị dị otú ahụ pụtara, a na-egosi onye ọrịa n'ọrịa nkwarụ, gụnyere, n'etiti ihe ndị ọzọ, mgbazi nke nguzozi-nnu mmiri.Dradọrọ Augmentin si kanhazi usoro na-emekwa ka usoro a dịrị ịba ọcha n'anya.

Nnabata nnabata nke ogwu a probenecid:

na-enyere aka belata tubular secretion nke amoxicillin,
na-akpalite mmụba nke ịta amoxicillin n'ime ọbara plasma (mmetụta ahụ dịruru ogologo oge),
anaghị emetụta Njirimara na ọkwa nke ọdịnaya plasma nke clavulanic acid.

Njikọ amoxicillin ya na allopurinol na-abawanye ohere nke mmepe na-apụta allergies. Data Mmekọrịta allopurinol N'otu oge ahụ akụkụ abụọ nke na-arụ ọrụ nke Augmentan anaghị anọ.

Augmentin nwere mmetụta dị n’ime ya microflora eriri afọ nke eriri afọnke ahụ na-akpalite mbelata nke reabsorption (iweghachi azụ) estrogen, yana mbelata na arụmọrụ jikọtara ọnụ ogwu mgbochi diri onu.

Ọgwụ a ekwekọghị n'ihe ngwaahịa ọbara na mmiri nwere protein, gụnyere gụnyere whey protein hydrolysates na abụba emulsion chọrọ itinye n’ime akwara.

Ọ bụrụ na edepụtara Augmentin n'otu oge ọgwụ nje klaasị aminoglycosides, agwaghị ọgwụ ndị ahụ n'otu sirinji ma ọ bụ arịa ọ bụla ọzọ tupu nchịkwa, ebe ọ bụ na nke a na-eduga n'ịgba ume aminoglycosides.

A na-echekwa nkwakọ ngwaahịa mbụ ahụ na okpomọkụ agaghị akarị 25 Celsius. Ekwesịrị idobe nkwusioru ahụ na ọnọdụ okpomọkụ 2-8 Celsius C (kachasị na friji) maka ihe na-erughị ụbọchị 7.

Ọ dị mma maka iji n'ime afọ 2 site na ụbọchị a rụpụtara.

Analogs nke AugmentinIhe dakọtara maka koodu ọkwa ọkwa ATX 4:

Analogs Augmentin bụ ọgwụ A-Klav-Farmeks, Amoxiclav, Amoxil-KBetaclava Clavamitin, Medoclave, Teraclav.

Nke ọ bụla n'ime ọgwụ ndị dị n'elu bụ ihe Augmentin nwere ike dochie ya na enweghị ya.

Ọnụahịa analogues dị iche iche site na 63.65 ruo 333.97 UAH.

Augmentin maka ụmụaka

A na-eji Augmentin eme ihe n'ọtụtụ ụmụaka. N'ihi eziokwu ahụ bụ na o nwere ụdị ntọhapụ ụmụaka - sirop, enwere ike iji ya na-emeso ụmụaka ruo otu afọ. N'ụzọ dị mkpa na-eme ka oriri nnabata na eziokwu na ọgwụ nwere ụtọ uto.

Maka umuaka ọgwụ nje na-akọwakarị maka akpịrị mgbu. A na-ekpebi usoro onyonye nke ụmụaka ahụ site afọ na ibu. A na-eke oke elele dị ka onyonyo abụọ, nke hà 45 mg / n'arọ kwa ụbọchị, ma ọ bụ ekewa atọ, usoro nke 40 mg / kg kwa ụbọchị.

Etu ị ga-esi theụọ ọgwụ ahụ maka ụmụaka yana ugboro ole usoro onunu ogwu dabere na usoro usoro onunu ogwu enyere.

Maka umuaka nke aru ha kariri 40 n'arọ, ka edeputara Augmentin otu ogwu ahu dika ndi oria okenye.

A na-eji Augmentin sirop maka ụmụaka ruo otu afọ na dosages nke 125 mg / 31.25 mg na 200 mg / 28.5 mg. Ekwuputara ọgwụ ọnụọgụ 400 mg / 57 mg maka ụmụaka karịrị otu afọ.

Aremụaka nọ n’agbata afọ isii na isii ruo iri isii (ihe dị ka kilogram 19) na-ahapụ ka ha depụta ma nkwusioru yana Augmentin na mbadamba. Usoro onunu ogwu nke udiri ogwu a di otu a:

otu mbadamba 250 mg + 125 mg ugboro atọ n'ụbọchị,
otu mbadamba 500 + 125 mg ugboro abụọ n'ụbọchị (ụdị usoro a bụ ezigbo).

Edebere ụmụaka gafere afọ 12 ka ha were otu mbadamba ụrọ nke 875 mg + 125 mg ugboro abụọ n'ụbọchị.

Iji tụọ dose nke ngwụcha Augmentin nke ọma maka ụmụaka na-erubeghị ọnwa 3, a na-atụ aro iji ụdị sirinji dee sirinji. Iji mee ka nkwusioru nke ụmụaka na-erubeghị afọ abụọ gbadata, a na-ahapụ ya ka ọ jiri mmiri wee ghee syrup ahụ na ogo 50/50

Ihe atụ nke Augmentin, nke bụ ọgwụ ya, bụ ọgwụ Amoxiclav, Flemoklav Solutab, Arlet, Rapiclav, Ecoclave.

Mmanya ndakọrịta

Augmentin na mmanya abụghị ndị na-emegide ya n'okpuru ị ofụ mmanya na-aba n'anya ọgwụ nje anaghị agbanwe Njirimara ọgwụ ya.

Ọ bụrụ n’ịzụlite usoro ọgwụgwọ ọgwụ ọjọọ, ọ dị mkpa ị drinkụ mmanya, ọ dị mkpa ịlele ọnọdụ abụọ: imeru ihe n’ókè na ịdị nfe.

Maka ndị na-arịa ị alcoholụbiga mmanya ókè, ị simụ ọgwụ ahụ n'otu oge iji mmanya nwere ike ịnwe nsonaazụ ka njọ.

Abuse abuseụbiga mmanya ókè n'ụzọ na-akpata ọgba aghara dị iche iche na-arụ ọrụ imeju. Ndi nwere oria imeju Ntụziaka ahụ na-atụ aro ka ejiri ọgwụ akpachara anya dezie Augmentin, ebe ọ bụ na eburu amụma etu akụkụ ahụ na-arịa ọrịa ga-esi akpa agwa ndị chọrọ ịnagide ya. xenobioticsiri ezigbo ike.

Ya mere, iji zere ihe ize ndụ na-ezighi ezi, a na-atụ aro ka ịhapụ ị alcoholụ mmanya n'oge oge ịgwọ ya na ọgwụ ahụ.

Augmentin n'oge afọ ime na lactation

Dị ka ọtụtụ ọgwụ nje penisilini otu, amoxicillin, nke ekesara n’arụ ahụ, na-abanyekwa n’ime mmiri ara. Ọzọkwa, ị ga-achọta ịta mmiri na mmiri ara ehi. acid clavulanic.

Agbanyeghị, ọ nweghị mmetụta dị njọ na ahụike ekwenyeghị na ọnọdụ nwatakịrị ahụ. N'ụfọdụ, nchikota acid clavulanic ya na amoxicillin nwere ike kpasuo nwa afọ ọsịsa na / ma ọ bụ candidiasis (thrush) nke akpụkpọ ahụ mucous n'ime oghere olu.

Augmentin so n ’ụdị ọgwụ eji eme nwa ara. Ọ bụrụ, n'agbanyeghị nke a, site na usoro ọgwụgwọ nne ji Augmentin, nwatakịrị ahụ nwere mmetụta uto na-adịghị mma, a na-akwụsị inye nwa ara.

Nnyocha ụmụ anụmanụ egosila na ihe ndị na-arụ ọrụ nke Augmentin nwere ike ịbanye mgbochi hematoplacental (GPB). Agbanyeghị, ọ nweghị mmetụta dị njọ na mmepe nwa ebu n’afọ ka amatapụtara.

Ọzọkwa, teratogenic mmetụta adịghị na ma parenteral ma nchịkwa nke ọgwụ.

Ojiji nke Augmentin n'ime ụmụ nwanyị dị ime nwere ike iduga mmepe nke nwa amụrụ ọhụrụ necrotizing enterocolitis (NEC).

Dịka ọgwụ ndị ọzọ niile, a naghị akwado Augmentin maka ụmụ nwanyị dị ime. N'oge ọmụmụ nwa, a ga-anabata ya naanị n'ọnọdụ ebe, dịka nyocha dọkịta si dị, uru dịịrị nwanyị gafere karịa ihe egwu nwatakịrị ya nwere.

Nyocha banyere Augmentin

Nyocha nke mbadamba na nkwụsị nke ụmụ Augmentin maka akụkụ kachasị nke oma. Ọtụtụ na-enyocha ọgwụ ahụ dị ka ọgwụgwọ dị irè na nke a pụrụ ịtụkwasị obi.

N'ọmụmụ ihe ebe ndị mmadụ na-ekwupụta mmetụta ha banyere ọgwụ ụfọdụ, nkezi ọgwụ akara bụ 4.3-4.5 n'ime 5 isi.

Nyochaa banyere Augmentin nke nne nke ụmụ na-eto eto na-egosi na ngwaọrụ ahụ na-enyere aka ngwa ngwa ịnagide ọrịa ndị dị ka nwata dị ka ọla kọpa ma obu akpịrị mgbu. Na mgbakwunye na ịdị mma nke ọgwụ, ndị nne na-ahụkwa ụtọ uto ya, nke ụmụaka nwere mmasị.

Ngwá ọrụ dịkwa irè n'oge afọ ime. N'agbanyeghị eziokwu ahụ na nkuzi ahụ anaghị atụ aro ka a na-emeso ụmụ nwanyị dị ime (karịchaa na 1st ọkara), a na-edekarị Augmentin na ọkara nke abụọ na nke atọ.

Dabere na ndị dọkịta, isi ihe mgbe ị na-eji ngwá ọrụ a bụ ịlele usoro onunu ogwu ma soro ndụmọdụ niile nke dọkịta gị.

Ọnụahịa Augmentin na Ukraine dịgasị iche dabere na ụlọ ahịa ọgwụ akọwapụtara. N'otu oge ahụ, ọnụ ahịa ọgwụ dị ntakịrị na ụlọ ahịa ọgwụ na Kiev, a na-ere mbadamba nkume na sirop na pharmacies na Donetsk, Odessa ma ọ bụ Kharkov na ọnụ ala dị ala.

A na-ere mbadamba 625 mg (500 mg / 125 mg) na ụlọ ahịa ọgwụ, na nkezi, na 83-85 UAH. Ọnụ ọnụ nke Augmentin mbadamba 875 mg / 125 mg - 125-135 UAH.

Can nwere ike ịzụta ọgwụ mgbochi n'ụdị ntụ ntụ maka nkwadebe nke ihe ngwọta maka injection ya na iji ọgwụ nke 500 mg / 100 mg nke ihe ndị na-arụ ọrụ, na nkezi, maka 218-225 UAH, ọnụ ahịa Augmentin 1000 mg / 200 mg - 330-354 UAH.

Ọnụahịa nkwụsị nke Augmentin maka ụmụaka:
400 mg / 57 mg (Augustmentin 2) - 65 UAH,
200 mg / 28.5 mg - 59 UAH,
600 mg / 42.9 mg - 86 UAH.

Pharlọ ọgwụ n'ịntanetị dị na Russia
Aclọ ahịa ọgwụ n'ịntanetị na UkraineUkraine
Pharmlọ ahịa ọgwụ dị n'ịntanetị na Kazakhstan

Augmentin ntụ ntụ 228.5 mg / 5 ml 7.7 g 70 ml GlaxoSmithKline

Mbadamba Augmentin 250 mg + 125 mg 20 pcs. GlaxoSmithKline

Augmentin ntụ ntụ 642.9 mg / 5 ml 100 ml

Augmentin ntụ ntụ 457 mg / 5 ml 12.6 g 70 ml

Augmentin ntụ ntụ 100 ml GlaxoSmithKline

Augmentin 250mg / 125mg Nke 20 mbadamba SmithKline Beech PiElSi

Augmentin 125mg / 31.25mg / 5ml 100ml ntụ ntụ maka nkwusioru SmithKline Beech PiElSi

Augmentin EU ntụ ntụ maka nkwụsị 600mg + 42.9mg Nke 1 karama GlaxoSmithKline

Augmentin 1000mg Nke 14 mbadamba SmithKline Beecham PiS

Augmentin 200mg / 28.5mg / 5ml 70ml ntụ ntụ maka nkwusioru SmithKline Beech PiElSi

IFlọ ọgwụ IFC

AugmentinSmithKline Beecham, UK

Ọgwụ Augmentin SB (UK)

Augmentin tab. 500mg / 125mg Nke 14 Velcom Foundation GW (UK)

Mpempe akwụkwọ Augmentin BD 625mg Nke 14 Velcom Foundation GW (UK)

Augmentin SRGlaxo Wellcome Production (France)

Augmentin ntụ ntụ maka ịkwadebe usoro ịgba ntụtụ 600mg Nke 10Glaxso Velcom GW (Great Britain)

Pharlọ ọgwụ Pani

Augmentin mgbe ahụ. d / p sirop 228.5mg / 5ml 70ml Glaxo Ọfụma

Augmentin 500 mg / 125 mg Nke 14 tab.p. Smithithline Beecham Pharmaceuticals (UK)

Augmentin 156 mg / 5 ml 100 ml por.d / sirop SmithKline Beecham Pharmaceuticals (UK)

Augmentin 400mg / 57mg / 5ml 35 ml por.d / kwụsị. SmithKline Beecham ọgwụ (UK)

Augmentin 875 mg / 125 mg Nke 14 tabl.smithKline Beecham Pharmaceuticals (Great Britain)

Augmentin 200mg / 28.5mg / 5ml 70 ml por.d / kwụsịtụ. SmithKline Beecham ọgwụ (UK)

Kwụsị uche! Ihe omuma banyere ogwu nke saịtị a bu ihe banyere nbuso-agha, anakpo ya site n public isi obodo ma na enweghi ike ibu ihe ndabere iji kpebie etu ogwu si di. Tupu ị Augụ ọgwụ Augmentin, jide n'aka ịkpọtụrụ dọkịta gị.

Nkọwa dị mkpa maka ya 26.09.2014

Aha Latin: Aha ya bụ Augmentin
Koodu ATX: J01CR02
Arụ Ọrụ: Amoxicillin (Amoxicillin) + Clavulanic acid (Clavulanic acid)
Emeputa: GlaxoSmithKline plc, UK

Na otu mbadamba onụ nwere 0,25, 0,5 ma ọ bụ 0.875 g amoxicillin trihydrate na 0.125 g acid clavulanic(N'ịmepụta ọgwụ ahụ, a na-etinye sodium clavulanate na ngafe 5%).

Agụnyere na ogwu ihe inyeaka: Silicii dioxydum colloidale, magnesium stearate, Carboxymethylamylum natricum, Cellulosum microcrystallicum.

Otu karama ntụ ntụ maka ịkwadebe ya maka injection nwere 0,5 ma ọ bụ 1 g amoxicillin trihydrate na, n'otu n'otu, 0.1 ma ọ bụ 0.2 g acid clavulanic.

Na ntụ ntụ Augmentin EU bu n’obi nkwadebe nke 100 ml nke nkwusiorunwere 0.6 g (5 ml) amoxicillin trihydrate na 0.0429 g (5 ml) acid clavulanic.

Ngwa ihe inyeaka: Silicii dioxydum colloidale, Carboxymethylamylum natricum), Aspartamum (E951), Xanthan gum, Silicii dioxydum, ahihia ahihia 544428.

Na nhazi nke otu Mbadamba ụrọ Augmentin CP na ogologo oge eme ihe gụnyere 1 g amoxicillin trihydrate na 0.0625 g acid clavulanic.

Pharmacodynamics na pharmacokinetics

Idochi anya transpeptidase na imeghari usoro nhazi mureina (akụkụ kachasị mkpa nke mgbidi nke mkpụrụ ndụ nje) n'oge nkewa na uto, ọ na-akpasu iwe nyocha (mbibi) nje.

A na-emebi Amoxicillin -lactamasesya mere ihe ogba-ama ya adighi erute ụmụ njena-arụpụta -lactamases.

Clavulanate na-etolite ogige ejiri rụọ ọrụ -lactamasesnke a na - egbochi mbibi amoxicillin.

Mkpụrụ ọgwụ Augmentin dị irè megide:

Aerobes (+) ikuku: pyogenic streptococcus otu A na B, pneumococci, Staphylococcus aureus na epidermal, (ewezuga ụdị nsogbu methicillin na-eguzogide), staflococcus saprophytic na ndị ọzọ
Ikuku (-) aerobes: Ogwe osisi Pfeiffer, Ukwara-nta, gardnerella vaginalis , cholera vibrio wdg
Gram (+) na gram (-) nke anaerobes: bacteroid, fusobacteria, preotellaswdg
Ihe microorganisms ndị ọzọ: chlamydia, spirochete, treponema paịlị wdg

Mgbe ogwachara Augmentin, ngwa ọrụ ya abụọ na-agbadata ngwa ngwa ma zuo ezu na ngọngọ nri. Ibepu abacha ihe zuru oke ma oburu na ị were ogwu ma obu sirop mgbe iri nri (na nmalite nri).

Abụọ mgbe e jiri ọnụ mee ya, yana iwebata ihe ngwọta nke Augmentin nke anọ, a na-ahụta usoro ọgwụgwọ nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ na akwara niile na mmiri.

Ngwaọrụ abụọ ahụ na-arụ ọrụ ike na-esighi ike protin ọbara nke plasma (ihe ruru 25% jikọrọ protein protein) amoxicillin trihydratena ọ dịghị ihe karịrị 18% acid clavulanic) Achọpụtaghị nchịkọta Augmentin na akụkụ ọ bụla dị n'ime.

Clavulanate site na akụrụ ya na site na usoro ndị ọzọ.

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Nke mbu, o na - enye nnabata ha nma nma Ọkpụkpụ afọ, na nke abuo, o nwere ike belata oke ihe obula eriri afọ dyspeptikọ bụrụ na nke ikpeazụ bụ ikpe.

Etu ị ga-esi gbakọọ ọgwụ Augmentin

Oge ọ na-anọ n’ọgwụ na-adabere n’otú ahụ onye ọrịa si emeghachi omume na ọgwụgwọ.

Mbadamba Augmentin: ntuziaka maka ojiji

Dabere na ọdịnaya nke ihe ndị na-arụ ọrụ n'ime ha, a na-atụ aro mbadamba Augmentin maka ndị ọrịa toro etozi dịka atụmatụ na-esote:

Augmentin 375 mg (250 mg + 125 mg) - otu ugboro atọ n'ụbọchị. N'ime usoro ogwu a, a na-egosi ọgwụ ahụ maka na-efe efenke ahụ na-abata mfe ma obu udi aru ike. N'ihe banyere ọrịa siri ike, gụnyere ọrịa na-adịghị ala ala na oge nlọghachi, a na-enye usoro ọgwụgwọ dị elu.
Mbadamba mbadamba 625 (500 mg + 125 mg) - otu ugboro atọ n'ụbọchị.
Mbadamba 1000 mg (875 mg + 125 mg) - otu ugboro abụọ n'ụbọchị.

Ogwu a dabere na ndị ọrịa nwere arụmọrụ arụmọrụ. akụrụ.

A na-anabata Augmentin CP 1000 mg / 62.5 mg mbadamba mbugharị ndị ọrịa maka ndị ọrịa karịrị afọ 16. Ihe kachasị mma bụ mbadamba abụọ ugboro abụọ n'ụbọchị.

Ọ bụrụ na onye ọrịa enweghị ike ilo mbadamba ihe niile, o kewara abụọ na ụzọ adịghị mma. A na-ewere halves abụọ n'otu oge.

Ntụ ntụ maka iji gwọọ ntụtụ: ntuziaka maka ojiji

Ọ bụrụ na echere na arụmọrụ ahụ ga-ewe ihe karịrị otu elekere, ruo ihe onunu anọ nke 1000 mg / 200 mg ka a na-enye onye ọrịa ahụ n’ụbọchị gara aga maka awa 24.

Nkwụsị Augmentin: ntuziaka maka ojiji

Taa, ọgwụ n'ụdị usoro dịgasị iche iche bụ otu n'ime ndị akachasị idebere maka ọgwụgwọ. ọnya afọ.

Analogs nke Augmentin

Analogs Augmentin bụ ọgwụ A-Klav-Farmeks, Amoxiclav, Amoxil-KBetaclava Clavamitin, Medoclave, Teraclav.

Nke ọ bụla n'ime ọgwụ ndị dị n'elu bụ ihe Augmentin nwere ike dochie ya na enweghị ya.

Ọnụahịa analogues dị iche iche site na 63.65 ruo 333.97 UAH.

Augmentin maka ụmụaka

Maka umuaka ọgwụ njena-akọwakarị maka akpịrị mgbu. A na-ekpebi usoro onyonye nke ụmụaka ahụ site afọ na ibu. A na-eke oke elele dị ka onyonyo abụọ, nke hà 45 mg / n'arọ kwa ụbọchị, ma ọ bụ ekewa atọ, usoro nke 40 mg / kg kwa ụbọchị.

Etu ị ga-esi theụọ ọgwụ ahụ maka ụmụaka yana ugboro ole usoro onunu ogwu dabere na usoro usoro onunu ogwu enyere.

Maka umuaka nke aru ha kariri 40 n'arọ, ka edeputara Augmentin otu ogwu ahu dika ndi oria okenye.

A na-eji Augmentin sirop maka ụmụaka ruo otu afọ na dosages nke 125 mg / 31.25 mg na 200 mg / 28.5 mg. Ekwuputara ọgwụ ọnụọgụ 400 mg / 57 mg maka ụmụaka karịrị otu afọ.

Aremụaka nọ n’agbata afọ isii na isii ruo iri isii (ihe dị ka kilogram 19) na-ahapụ ka ha depụta ma nkwusioru yana Augmentin na mbadamba. Usoro onunu ogwu nke udiri ogwu a di otu a:

otu mbadamba 250 mg + 125 mg ugboro atọ n'ụbọchị,
otu mbadamba 500 + 125 mg ugboro abụọ n'ụbọchị (ụdị usoro a bụ ezigbo).

Edebere ụmụaka gafere afọ 12 ka ha were otu mbadamba ụrọ nke 875 mg + 125 mg ugboro abụọ n'ụbọchị.

Ihe atụ nke Augmentin, nke bụ ọgwụ ya, bụ ọgwụ Amoxiclav, Flemoklav Solutab, Arlet, Rapiclav, Ecoclave.

Mmanya ndakọrịta

Augmentin na mmanya abụghị ndị na-emegide ya n'okpuru ị ofụ mmanya na-aba n'anya ọgwụ njeanaghị agbanwe Njirimara ọgwụ ya.

Ọ bụrụ n’ịzụlite usoro ọgwụgwọ ọgwụ ọjọọ, ọ dị mkpa ị drinkụ mmanya, ọ dị mkpa ịlele ọnọdụ abụọ: imeru ihe n’ókè na ịdị nfe.

Maka ndị na-arịa ị alcoholụbiga mmanya ókè, ị simụ ọgwụ ahụ n'otu oge iji mmanya nwere ike ịnwe nsonaazụ ka njọ.

Ya mere, iji zere ihe ize ndụ na-ezighi ezi, a na-atụ aro ka ịhapụ ị alcoholụ mmanya n'oge oge ịgwọ ya na ọgwụ ahụ.

Augmentin n'oge afọ ime na lactation

Ọzọkwa, teratogenic mmetụta adịghị na ma parenteral ma nchịkwa nke ọgwụ.

Ojiji nke Augmentin n'ime ụmụ nwanyị dị ime nwere ike iduga mmepe nke nwa amụrụ ọhụrụ necrotizing enterocolitis (NEC).

Nyocha banyere Augmentin

N'ọmụmụ ihe ebe ndị mmadụ na-ekwupụta mmetụta ha banyere ọgwụ ụfọdụ, nkezi ọgwụ akara bụ 4.3-4.5 n'ime 5 isi.

Dabere na ndị dọkịta, isi ihe mgbe ị na-eji ngwá ọrụ a bụ ịlele usoro onunu ogwu ma soro ndụmọdụ niile nke dọkịta gị.

Ọnụahịa Augmentin

A na-ere mbadamba 625 mg (500 mg / 125 mg) na ụlọ ahịa ọgwụ, na nkezi, na 83-85 UAH. Ọnụ ọnụ nke Augmentin mbadamba 875 mg / 125 mg - 125-135 UAH.

Ọnụahịa nkwụsị nke Augmentin maka ụmụaka:
400 mg / 57 mg (Augustmentin 2) - 65 UAH,
200 mg / 28.5 mg - 59 UAH,
600 mg / 42.9 mg - 86 UAH.

Nkọwa nke ụdị usoro onunu ogwu

Ntụ ntụ: ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, nwere njirimara na-esi isi. Mgbe diluted, etisasị na-acha ọcha ma ọ bụ ihe fọrọ nke nta ọcha. Mgbe ị kwụ ọtọ, ihe na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke ọma na-eji nwayọọ nwayọọ.

Mbadamba ụrọ, 250 mg + 125 mg: kpuchie ya na ihe nkiri site na ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha, oval ke udi, ya na ihe odide a bu "AUGMENTIN" n'otu akụkụ. N'oge kink: site na ọcha na-acha odo odo ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

Mbadamba ụrọ, 500 mg + 125 mg: kpuchie ya n'ọbọ ihe nkiri site na ọcha rue ihe fọrọ nke nta ka ọ bụrụ ọcha na agba, oval, nke e dere ihe akpọrọ "AC" yana ihe egwu dị n'otu akụkụ.

Mbadamba ụrọ, 875 mg + 125 mg: kpuchie ya n'ọbọ ihe nkiri site na ọcha rue ihe fọrọ nke nta ka ọ bụrụ ọcha, na oval n'ụdị ya, ya na mkpụrụedemede "A" na "C" n'akụkụ ya na ahịrị mmebi dị n'otu akụkụ. N'oge kink: site na ọcha na-acha odo odo ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

Na-egosi Augmentin ®

ọrịa elu akụkụ akụkụ iku ume (gụnyere ọrịa ENT), dịka ọmụmaatụ tonsillitis, sinusitis, otitis media, na-ebutekarị Ahụ ike oyi na-akpata prọdia, Hemophilus influenza 1, Moraxella catarrhalis 1 na plogenes nke Streptococcus, (ewezuga mbadamba Augmentin 250 mg / 125 mg),

Ọrịa dị ala nke akụkụ okuku ume na akwara, dị ka nkụda mmụọ nke ụkwara ume ọkụ, ụkwara ume ọkụ, na ọnya na-efe efe, bụ́ nke na-akpatakarị. Ahụ ike oyi na-efe efe nke Hemophilus 1 na Moraxella catarrhalis 1,

ọrịa ọnya na-efe efe, dị ka cystitis, urethritis, pyelonephritis, ọrịa nke akụkụ nke akụkụ nke nwanyị, nke na-akpatakarị ụdị ezinụlọ. Enterobacteriaceae 1 (nke ka nke Escherichia coli 1 ), Staphylococcus saprophyticus na umu Enterococcusyana gonorrhea kpatara Neisseria gonorrhoeae 1,

Akpịrị anụ ahụ na anụ ahụ dị nro na-ebutekarị Staphylococcus aureus 1, pyogenes Streptococcus na umu Bacteroides 1,

Ọkpụkpụ nke ọkpụkpụ na nkwonkwo, dịka osteomyelitis, na-ebutekarị Staphylococcus aureus 1, ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume ịgwọ ọrịa ogologo oge.

ọrịa odontogenic, dịka ọmụmaatụ periodontitis, odontogenic maxillary sinusitis, ọnya ezé siri ike na mgbasa cellulite (naanị maka mkpụrụ osisi Augmentin, ọnụọgụ 500 mg / 125 mg, 875 mg / 125 mg),

ọrịa ndị ọzọ jikọtara ọnụ (dịka ọmụmaatụ, afọ ime septic, postpartum sepsis, serais intraabdominal) dị ka akụkụ nke usoro ọgwụgwọ (naanị maka mbadamba Augmentin usoro onodu ogwu 250 mg / 125 mg, 500 mg / 125 mg, 875 mg / 125 mg),

1 Ndị nnọchite anya nke ụdị microorganisms akọwapụtara na-emepụta beta-lactamase, nke na-eme ka ha bụrụ ndị na-enweghị mmetụta na amoxicillin (lee. Pharmacodynamics).

Ọrịa Augmentin be nwere ike ịgwọ ọrịa ndị microorganisms na-emetụta amoxicillin, ebe ọ bụ na amoxicillin bụ otu n'ime ihe ndị dị na ya. Augmentin ® ka egosiri maka ọgwụgwọ nke ọrịa nje jikọtara nke microorganisms nke nwere amoxicillin, yana microorganisms na-emepụta beta-lactamase, na-emetụta nchikota nke amoxicillin na clavulanic acid.

Usoro onunu ogwu na nhazi

Usoro usoro onunu ogwu ka edobere n’otu n’otu, dabere n’afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji belata nsị nke oghere ga-ekwe omume na iwelata ohere ị ,ụ mmanya, a ga-a drugụ ọgwụ ahụ na mbido nri. Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, a ga - enwe ike ịme ọgwụgwọ na - aga ije (usoro nchịkwa mbụ nke ọgwụ ahụ na ntinye ga - esote ya na nchịkwa ọnụ).

Ekwesịrị icheta ya na taabụ 2 ahụ. Augmentin ®, 250 mg + 125 mg ezughị 1 mbadamba. Augmentin ®, 500 mg + 125 mg.

Ndị okenye na ụmụaka gbara afọ 12 gbagoro ma ọ bụ karịa 40 n'arọ ma ọ bụ karịa. Ọ na-atụ aro iji 11 ml nke nkwusioru na usoro nke 400 mg + 57 mg na 5 ml, nke ya na 1 tebụl. Augmentin ®, 875 mg + 125 mg.

Taabụ 1. 250 mg + 125 mg ugboro atọ kwa ụbọchị maka ọrịa ọ bụla na-arịa obere nfe. Na ọrịa dị egwu (gụnyere ọrịa ọnya ụkwara na-adị ala, na-esochi ọria, nke na-adịghị ala ala na nke na-esochi ọrịa iku ume), a na-atụ aro usoro ndị ọzọ nke Augmentin..

Taabụ 1. 500 mg + 125 mg ugboro atọ n'ụbọchị.

Taabụ 1. 875 mg + 125 mg 2 ugboro n'ụbọchị.

Agedmụaka dị n’agbata ọnwa atọ ruo afọ iri na abụọ n’arụ ahụ́ ya erughị 40 n'arọ. A na-eme ngụkọta oge dabere na afọ na oke ahụ, nke egosipụtara na mg / kg / ụbọchị ma ọ bụ na ml nke nkwusioru. A na-ekewa ọgwụ kwa ụbọchị ka usoro 3 kwa awa asatọ ọ bụla (125 mg + 31.25 mg) ma ọ bụ 2 doses kwa awa 12 ọ bụla (200 mg + 28.5 mg, 400 mg + 57 mg). Usoro usoro usoro onunu ogwu a ka akwadoro ka ana egosiputa ya na oge oru ya na tebulu di n'okpuru.

Usoro Augmentin s usoro onunu ogwu (gbakọọ agbakọọ dabere na amoxicillin)

A na-atụ aro iji obere Augmentin ® maka ọgwụgwọ nke ọrịa anụ ahụ na anụ ahụ dị nro, yana tonsillitis ugboro ugboro.

A na-akwado ọgwụ ka ukwuu nke Augmentin for maka ọgwụgwọ nke ọrịa dịka otitis media, sinusitis, ọrịa nke akụkụ okuku ume na ọnya afọ, ọrịa nke ọkpụkpụ na nkwonkwo.

Enwebeghị data data dị n'ụlọ ọgwụ iji tụọ ọgwụ Augmentin drug na ọgwụ nke ihe karịrị 40 mg + 10 mg / kg na usoro 3 kewara (4: 1 nkwusioru) na ụmụaka na-erubeghị afọ abụọ.

Umuaka site na omumu rue onwa ato. N'ihi ezumike nke akụrụ ahụ, ọgwụ a tụrụ aro ya nke Augmentin ® (gbakọọ maka amoxicillin) bụ 30 mg / n'arọ / ụbọchị n'ime usoro 2 nke 4: 1.

Umu amuru n’azu. Enweghị ntuziaka maka usoro usoro usoro onunu ogwu.

Ndị otu ọrịa pụrụ iche

Ndị okenye na-arịa ọrịa. Achọghị usoro maka usoro usoro usoro onunu ogwu ahụ; a na-etinye otu usoro usoro usoro ahụ ka ọ dị na ndị ọrịa na-eto eto. N'ime ndị ọrịa agadi nwere ezumike ọrụ ezumike, a na-enye usoro ọgwụgwọ kwesịrị ekwesị maka ndị ọrịa toro eto nwere ọrụ mgbazi arụ.

Ndị ọrịa nwere ọria imeju. A na- eji nlezianya na-agwọ ọgwụgwọ; a na-enyocha ọrụ imeju. Enweghi data zuru oke iji gbanwee ntuziaka maka ọgwụ ndị ọrịa dị otú ahụ.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu. Ntuzi nke usoro onunu ogwu sitere na oke agbadoro anya nke amoxicillin na uru ikike idozi.

Usoro Augmentin ® usoro onunu ogwu

Mbadamba ihe eji etinye fim, 250 mg + 125 mg: mmeghari onunu ogwu dabere na oke okacha amara nke amoxicillin.

2 taabụ. 250 mg + 125 mg na 1 dose kwa awa 24

N'oge nnọkọ omalụ a, ihe ọzọ 1 (1 mbadamba) na mbadamba 1 ọzọ. na njedebe nke nnọkọ omalụ (iji kwụọ ụgwọ mbelata nke serum nke amoxicillin na clavulanic acid).

Mbadamba ihe eji etinye fim, 500 mg + 125 mg: mmeghari onunu ogwu dabere na oke okacha amara nke amoxicillin.

Taabụ 1. 500 mg + 125 mg na 1 dose kwa awa 24

N'oge nnọkọ omalụ a, ihe ọzọ 1 (1 mbadamba) na mbadamba 1 ọzọ. na njedebe nke nnọkọ omalụ (iji kwụọ ụgwọ mbelata nke serum nke amoxicillin na clavulanic acid).

Ofzọ nkwadebe nke nkwusioru

A kwadebere nkwusioru ya ozugbo tupu ojiji izizi. Ihe dị ka milimita 60 nke esi esi mmiri ga-eme ka ekpomoku dị n'ime mmiri ahụ etinyere ya na karama ntụ ahụ, wee mechie karama ahụ na mkpuchi wee maa jijiji ruo mgbe ntụ ọka ahụ kpamkpam, kwe ka karama ahụ kwụrụ ruo minit 5 iji hụ na ngwakọta zuru ezu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 92 ml mmiri iji kwadebe nkwusioru maka ọgwụ nke 125 mg + 31.25 mg na 64 ml mmiri maka usoro onunu ogwu nke 200 mg + 28.5 mg na 400 mg + 57 mg.

Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ accurateụ accurateụ ziri ezi, a ga-eji okpu eji atụ ahụ, nke a ga-eji mmiri wee saa ya nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka umuaka n’agbata afo abuo, ihe omuma nke ntughari ogwu Augmentin ® nwere ike with jiri mmiri rita 1: 1.

Mpempe mwepụta

Mbadamba ụbụrụ - mkpụrụ osisi iri na anọ kwa otu

Omume ọgwụ

Mkpokọta ọgwụ nje nke na-egbochi ọgwụ β-lactamase nke nwere amoxicillin na acid clavulanic.

Clavulanic acid, ihe β-lactamase inhibitor nke metụtara penisilini, nwere ike ime ka ihe dị iche iche β-lactamases ndị dị na penisilini na cephalosporin na-eguzogide ọgwụ.

Ọnụnọ nke clavulanic acid dị na nkwadebe Augmentin CP na-echebe amoxicillin site na mbibi site na enzymes - β-lactamases, nke na-enye ohere ịgbasa ụdị antibacterial nke amoxicillin.

Ihe ngosi maka ojiji

Nje virus nke bakteria na-akpata:

Ọrịa nke akụkụ okuku ume na elu akụkụ akụkụ ENT (dịka ọmụmaatụ ụkwara ume ọkụ ugboro ugboro, sinusitis, otitis media), na-ebutekarịkarị akpịrị Streptococcus pneumoniae, ọkụ ọkụ Haemophilus, Moraxella catarrhalis, pulgenesptoptoccccus,
Ọrịa ọgbụgbọ na-adịghị ala ala: ihe na-akpata ọrịa bronchitis na-adịghị ala ala, ọnya ọgbụgbọ na lobar na bronchopneumonia, na-akpatakarị ọrịa akpịrị gbara oyi nke ọrịa kọfịkịtị Haemophilus na Moraxella catarrhalis (ma e wezụga mbadamba 250 mg / 125 mg),
Ọrịa urinary na-efe efe: cystitis, urethritis, pyelonephritis, ọrịa nke akụkụ ahụ nwanyị, nke na-ebutekarị site na ụdị nke ezinụlọ Enterobacteriaceae (ọkachasị nke Escherichia coli *), staphylococcus saprophyticus na ụdị ụdị mkpụrụ ndụ Enterococcus,
gonorrhoea nke Neisseria gonorrhoeae kpatara (ma ọ bụghị mbadamba 250 mg / 125 mg),
Ọria na akpukpo anụ ahụ na anụ ahụ dị nro, nke a na-ebutekarị site na Staphylococcus aureus, Streptococcus pyogenes na ụdị mkpụrụ ndụ ihe nketa Bactero> Usoro ọgwụgwọ na nchịkwa

A na-edobe usoro usoro onunu ogwu n'otu oge dabere na afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji were mee nke ọma ma belata nsonaazụ ndị enwere ike na sistemụ nri, a na-atụ aro Augmentin ka ebido n'isi nri.

Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume duziri ọgwụ (na mmalite ọgwụgwọ, parenteral management of the ọgwụ with sochiri transition to oral management).

Ihe ngbanwe

hypersensitivity na amoxicillin, clavulanic acid, ihe ndị ọzọ dị na ọgwụ ahụ, ọgwụ mgbochi beta-lactam (dịka penicillins, cephalosporins) na anamnesis,
ihe omume gara aga nke jaundice ma ọ bụ ọrụ imeju na-arụ ọrụ mgbe ị na-ejikọkọta ọgwụ amoxicillin na clavulanic acid na akụkọ ntolite.
ụmụaka na-erubeghị afọ 12 na ahụ ha erughị 40 n'arọ

Ọnọdụ nchekwa

Ekwesịrị ịchekwa ọgwụ ahụ ka ụmụaka ghara iru ya na okpomọkụ agaghị agafe 25 Celsius.

Na otu mbadamba onụ nwere 0,25, 0,5 ma ọ bụ 0.875 g amoxicillin trihydrate na 0.125 g acid clavulanic (N'ịmepụta ọgwụ ahụ, a na-etinye sodium clavulanate na ngafe 5%).

Agụnyere na ogwu ihe inyeaka: Silicii dioxydum colloidale, magnesium stearate, Carboxymethylamylum natricum, Cellulosum microcrystallicum.

Otu karama ntụ ntụ maka ịkwadebe ya maka injection nwere 0,5 ma ọ bụ 1 g amoxicillin trihydrate na, n'otu n'otu, 0.1 ma ọ bụ 0.2 g acid clavulanic.

Na ntụ ntụ Augmentin EU bu n’obi nkwadebe nke 100 ml nke nkwusiorunwere 0.6 g (5 ml) amoxicillin trihydrate na 0.0429 g (5 ml) acid clavulanic.

Ngwa ihe inyeaka: Silicii dioxydum colloidale, Carboxymethylamylum natricum), Aspartamum (E951), Xanthan gum, Silicii dioxydum, ahihia ahihia 544428.

Na nhazi nke otu Mbadamba ụrọ Augmentin CP na ogologo oge eme ihe gụnyere 1 g amoxicillin trihydrate na 0.0625 g acid clavulanic.

Ọgwụ nwere ụdị nnabata ndị a:

Mbadamba Augmentin 250 mg + 125 mg, Augmentin 500 mg + 125 mg na Augmentin 875 + 125 mg.
Powder 500/100 mg na 1000/200 mg, bu n’obi maka nkwadebe nke ihe eji egbu egbu.
Ntụ maka nkwụsị Augmentin 400 mg / 57 mg, 200 mg / 28.5 mg, 125 mg / 31.25 mg.
Ntụ ntụ Augmentin EU 600 mg / 42.9 mg (5 ml) maka nkwusioru.
Augmentin CP 1000 mg / 62.5 mg nwere mbadamba mbugharị ha

Augmentin bụ ndị otu ọgwụ ọgwụ ọgwụ "ọgwụ antimicrobial maka iji usoro. -lactams. Penicillins. ”

Mmetụta ọgwụ ọgwụ dị ọgwụ nje na ọgwụ nje.

Pharmacodynamics na pharmacokinetics

Idochi anya transpeptidase na imeghari usoro nhazi mureina (akụkụ kachasị mkpa nke mgbidi nke mkpụrụ ndụ nje) n'oge nkewa na uto, ọ na-akpasu iwe nyocha (mbibi) nje.

A na-emebi Amoxicillin -lactamasesya mere ihe ogba-ama ya adighi erute ụmụ njena-arụpụta -lactamases.

Clavulanate na-etolite ogige ejiri rụọ ọrụ -lactamasesnke a na - egbochi mbibi amoxicillin.

Mkpụrụ ọgwụ Augmentin dị irè megide:

Aerobes (+) ikuku: pyogenic streptococcus otu A na B, pneumococci, Staphylococcus aureus na epidermal, (ewezuga ụdị nsogbu methicillin na-eguzogide), staflococcus saprophytic na ndị ọzọ
Ikuku (-) aerobes: Ogwe osisi Pfeiffer, Ukwara-nta, gardnerella vaginalis , cholera vibrio wdg
Gram (+) na gram (-) nke anaerobes: bacteroid, fusobacteria, preotellas wdg
Ihe microorganisms ndị ọzọ: chlamydia, spirochete, treponema paịlị wdg

Mgbe ogwachara Augmentin, ngwa ọrụ ya abụọ na-agbadata ngwa ngwa ma zuo ezu na ngọngọ nri. Ibepu abacha ihe zuru oke ma oburu na ị were ogwu ma obu sirop mgbe iri nri (na nmalite nri).

Abụọ mgbe e jiri ọnụ mee ya, yana iwebata ihe ngwọta nke Augmentin nke anọ, a na-ahụta usoro ọgwụgwọ nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ na akwara niile na mmiri.

Clavulanate site na akụrụ ya na site na usoro ndị ọzọ.

Ihe ngosi maka ojiji

Ihe ngosiputa maka ojiji amoxicillin trihydrate na acid clavulanic bụ na-efe efemkpasu iwe banyere ihe ndia ụmụ nje.

Na Internetntanetị, a na-ajụkarị ajụjụ “Kedu mkpụrụ mbido Augmentin? "Ma ọ bụ" Gịnị bụ Augmentin Syrup Curing? ".

Okirikiri nke ọgwụ a sara mbara. Edere ya na ihe ndị a ọrịa na-efe efe na mkpali:

na na-efe efena-emetụta elu na ala iku ume ala (gụnyere gụnyere Ọrịa ENT),
na na-efe efena-emetụta ọnya mkpụrụ ndụ,
na odontogenic (onu n’onu) oria,
na ọrịa gynecological,
na ọgbụgba,
na na-efe efena-emetụta anụ ahụ na anụ ahụ dị nro,
na na-efe efena-emetụta anụ ahụ (gụnyere ma ọ bụrụ na ọ dị mkpa, nhọpụta nke onye ọrịa ogologo oge),
ihe ndi ozo na-efe efe ụdị agwakọta (dịka ọmụmaatụ ẹphe tụko iphena sepsis n'oge nke ọmụmụ, na ọrịa mbufụt (sepsis na-enweghị metastases), peritonitisna sepsiskpatara ọrịa intraabdominalna na-efe efena-emepe emepe ihe ogwugwo).

Augmentin n'ụdị usoro onunu ogwu ka contraindicated:

ndị ọrịa nwere ọgwụ mgbochi otu ma ọ bụ akụkụ abụọ nke ọgwụ ahụ, nye onye ọ bụla n'ime ya, yana -lactam (i.e. to ọgwụ nje site na otu penisilini na cephalosporin),
ndị ọrịa nwetagogola usoro ọgwụgwọ Augmentin jaundice ma ọ bụ akụkọ banyere arụ ọrụ imeju n'ihi ojiji nke ngwakọta nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ.

Mgbakwunye mgbochi ọzọ na nhọpụta ụrọ maka nkwadebe nke nkwusioru ọnụ yana iji ọgwụ nke ihe arụ ọrụ 125 + 31.25 mg bụ PKU (phenylketonuria).

A na-egbochi ntụ ntụ iji kwadebe nkwusioru nke ọnụ na-eji ya eme ihe (200 + 28.5) na (400 + 57) mg:

na PKU,
ndị ọrịa nwere nsogbu akụrụna nke egosi Reberg nwale n'okpuru 30 ml kwa nkeji
ụmụaka na-erubeghị afọ atọ.

Mgbakwunye ọzọ maka iji mbadamba nkume nwere ọgwụ ihe eji eme ihe (250 + 125) na (500 + 125) mg bụ afọ n'okpuru afọ iri na abụọ na / ma ọ bụ ibu na-erughị kilogram 40.

Mbadamba ọgwụ nwere ọgwụ ike 875 + 125 mg na-egbochi ọgwụ:

mebie ọrụ arụmọrụ akụrụ (ndị na-egosi Reberg nwale n'okpuru 30 ml kwa nkeji)
ụmụaka na-erubeghị afọ iri na abụọ
ndị ọrịa nke ịdị arọ ya anaghị agafe 40 n'arọ.

Nsonaazụ nke Augmentin nwere ike ime site na sistemụ na akụkụ mmadụ dị iche iche.Ọtụtụ mgbe, megide ndabere nke ọgwụgwọ ọgwụ, enwere ike ibute mmeghachi omume ndị a:

candidiasis (thrush) akpụkpọ ahụ na akpụkpọ anụ mucous,
afọ ọsịsa (oge niile - mgbe ị na-ewere Augmentin na mbadamba, oge ụfọdụ mgbe ị na -ekwụsịtụ ma ọ bụ na-abanye ọgwụ ahụ),
ọgbụgbọ na ọgbụgbọ (ọgbụgbọ na-abụkarị mgbe ị na-a theụ ọgwụ ahụ na oke doses).

Mmetụta ọghọm ọ na-erite na-enweghị oge ịgụnye:

anya ntughari,
isi ọwụwa,
dysfunctions mgbaze,
mmụba dị nta na ọrụ enzyme imeju omarnine transaminases (ALT) na asmitate transaminases (AST),
akpukpo aru, akpụkpọ anụ?ekpughere urticaria.

N'ọnọdụ ndị a na-adịghị ahụkebe, ahụ nwere ike ịzaghachi nnabata nke Augmentin:

atụgharị leukopenia (gụnyere gụnyere agranulocytosis),
thrombocytopenia,
mmepe thrombophlebitis n’ebe a na-agba ya ọgwụ
polymorphic erythema.

Ọ dịkarịghị ike ịmalite:

hemolytic anaemia,
ọnọdụ e ji mmụba na-egbu oge ọbara ọgbụgba na abawanye ntụpọ prothrombin,
mmeghachi omume sitere na na dịghịzi usoronke egosiri dika angioedema, ọrịa nke yiri nke ahụ gosipụtara ọrịa ọbara, anafilaisis, nfụkasị vasculitis,
hyperactivity ụdị enwere ike ịgbanwe
abawanye ihe omimi,
pricksn'ihi nnabata ọgwụ njegụnyere gụnyere pseudomembranous (PMK) na ọbara ọgbụgba (enwere ike itolite nke ikpe-azụ na-ebelata ma ọ bụrụ na a na-achịkwa Augmentin parenterally),
keratinization na uto nke papillae udi nwere ire (oria akporo 'asusu nwere ntutu'),
ịba ọcha n'anya na cholestasis intrahepatic,
Ọrịa Lyell,
juputara na pustulosis na-ahụ anya n'ụdị siri ike
interstitial nephritis,
Ngosipụta na mmamịrị nke kristal nnu (kristalia).

Bụrụ na nke ọ bụla ọrịa akpịrị A ga-akwụsị ịgwọ ọrịa nfụkasị Ọdụdọ Augmentin.

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Nke mbu, o na - enye nnabata ha nma nma Ọkpụkpụ afọ, na nke abuo, o nwere ike belata oke ihe obula eriri afọ dyspeptikọ bụrụ na nke ikpeazụ bụ ikpe.

Etu ị ga-esi gbakọọ ọgwụ Augmentin

Oge ọ na-anọ n’ọgwụ na-adabere n’otú ahụ onye ọrịa si emeghachi omume na ọgwụgwọ.

Mbadamba Augmentin: ntuziaka maka ojiji

Dabere na ọdịnaya nke ihe ndị na-arụ ọrụ n'ime ha, a na-atụ aro mbadamba Augmentin maka ndị ọrịa toro etozi dịka atụmatụ na-esote:

Augmentin 375 mg (250 mg + 125 mg) - otu ugboro atọ n'ụbọchị. N'ime usoro ogwu a, a na-egosi ọgwụ ahụ maka na-efe efenke ahụ na-abata mfe ma obu udi aru ike. N'ihe banyere ọrịa siri ike, gụnyere ọrịa na-adịghị ala ala na oge nlọghachi, a na-enye usoro ọgwụgwọ dị elu.
Mbadamba mbadamba 625 (500 mg + 125 mg) - otu ugboro atọ n'ụbọchị.
Mbadamba 1000 mg (875 mg + 125 mg) - otu ugboro abụọ n'ụbọchị.

Ogwu a dabere na ndị ọrịa nwere arụmọrụ arụmọrụ. akụrụ.

A na-anabata Augmentin CP 1000 mg / 62.5 mg mbadamba mbugharị ndị ọrịa maka ndị ọrịa karịrị afọ 16. Ihe kachasị mma bụ mbadamba abụọ ugboro abụọ n'ụbọchị.

Ọ bụrụ na onye ọrịa enweghị ike ilo mbadamba ihe niile, o kewara abụọ na ụzọ adịghị mma. A na-ewere halves abụọ n'otu oge.

Ntụ ntụ maka iji gwọọ ntụtụ: ntuziaka maka ojiji

Ọ bụrụ na echere na arụmọrụ ahụ ga-ewe ihe karịrị otu elekere, ruo ihe onunu anọ nke 1000 mg / 200 mg ka a na-enye onye ọrịa ahụ n’ụbọchị gara aga maka awa 24.

Nkwụsị Augmentin: ntuziaka maka ojiji

Taa, ọgwụ n'ụdị usoro dịgasị iche iche bụ otu n'ime ndị akachasị idebere maka ọgwụgwọ. ọnya afọ.

Ceedgafe ogo nke Augmentin na-eso:

mmepe nke imebi site na ngwe nri,
imebi nguzo nke nnu-mmiri,
kristalia,
gbasara akwara,
ọdịda (ọdịda) nke amoxicillin na urinary catheter.

Mgbe mgbaàmà ndị dị otú ahụ pụtara, a na-egosi onye ọrịa n'ọrịa nkwarụ, gụnyere, n'etiti ihe ndị ọzọ, mgbazi nke nguzozi-nnu mmiri. Dradọrọ Augmentin si kanhazi usoro na-emekwa ka usoro a dịrị ịba ọcha n'anya.

Nnabata nnabata nke ogwu a probenecid:

na-enyere aka belata tubular secretion nke amoxicillin,
na-akpalite mmụba nke ịta amoxicillin n'ime ọbara plasma (mmetụta ahụ dịruru ogologo oge),
anaghị emetụta Njirimara na ọkwa nke ọdịnaya plasma nke clavulanic acid.

Ọgwụ a ekwekọghị n'ihe ngwaahịa ọbara na mmiri nwere protein, gụnyere gụnyere whey protein hydrolysates na abụba emulsion chọrọ itinye n’ime akwara.

Ọ dị mma maka iji n'ime afọ 2 site na ụbọchị a rụpụtara.

Analogs nke AugmentinIhe dakọtara maka koodu ọkwa ọkwa ATX 4:

Analogs Augmentin bụ ọgwụ A-Klav-Farmeks, Amoxiclav, Amoxil-KBetaclava Clavamitin, Medoclave, Teraclav.

Nke ọ bụla n'ime ọgwụ ndị dị n'elu bụ ihe Augmentin nwere ike dochie ya na enweghị ya.

Ọnụahịa analogues dị iche iche site na 63.65 ruo 333.97 UAH.

Augmentin maka ụmụaka

Etu ị ga-esi theụọ ọgwụ ahụ maka ụmụaka yana ugboro ole usoro onunu ogwu dabere na usoro usoro onunu ogwu enyere.

Maka umuaka nke aru ha kariri 40 n'arọ, ka edeputara Augmentin otu ogwu ahu dika ndi oria okenye.

A na-eji Augmentin sirop maka ụmụaka ruo otu afọ na dosages nke 125 mg / 31.25 mg na 200 mg / 28.5 mg. Ekwuputara ọgwụ ọnụọgụ 400 mg / 57 mg maka ụmụaka karịrị otu afọ.

Aremụaka nọ n’agbata afọ isii na isii ruo iri isii (ihe dị ka kilogram 19) na-ahapụ ka ha depụta ma nkwusioru yana Augmentin na mbadamba. Usoro onunu ogwu nke udiri ogwu a di otu a:

otu mbadamba 250 mg + 125 mg ugboro atọ n'ụbọchị,
otu mbadamba 500 + 125 mg ugboro abụọ n'ụbọchị (ụdị usoro a bụ ezigbo).

Edebere ụmụaka gafere afọ 12 ka ha were otu mbadamba ụrọ nke 875 mg + 125 mg ugboro abụọ n'ụbọchị.

Ihe atụ nke Augmentin, nke bụ ọgwụ ya, bụ ọgwụ Amoxiclav, Flemoklav Solutab, Arlet, Rapiclav, Ecoclave.

Mmanya ndakọrịta

Augmentin na mmanya abụghị ndị na-emegide ya n'okpuru ị ofụ mmanya na-aba n'anya ọgwụ nje anaghị agbanwe Njirimara ọgwụ ya.

Ọ bụrụ n’ịzụlite usoro ọgwụgwọ ọgwụ ọjọọ, ọ dị mkpa ị drinkụ mmanya, ọ dị mkpa ịlele ọnọdụ abụọ: imeru ihe n’ókè na ịdị nfe.

Maka ndị na-arịa ị alcoholụbiga mmanya ókè, ị simụ ọgwụ ahụ n'otu oge iji mmanya nwere ike ịnwe nsonaazụ ka njọ.

Ya mere, iji zere ihe ize ndụ na-ezighi ezi, a na-atụ aro ka ịhapụ ị alcoholụ mmanya n'oge oge ịgwọ ya na ọgwụ ahụ.

Augmentin n'oge afọ ime na lactation

Dị ka ọtụtụ ọgwụ nje penisilini otu, amoxicillin, nke ekesara n’arụ ahụ, na-abanyekwa n’ime mmiri ara.Ọzọkwa, ị ga-achọta ịta mmiri na mmiri ara ehi. acid clavulanic.

Ọzọkwa, teratogenic mmetụta adịghị na ma parenteral ma nchịkwa nke ọgwụ.

Ojiji nke Augmentin n'ime ụmụ nwanyị dị ime nwere ike iduga mmepe nke nwa amụrụ ọhụrụ necrotizing enterocolitis (NEC).

Nyocha banyere Augmentin

N'ọmụmụ ihe ebe ndị mmadụ na-ekwupụta mmetụta ha banyere ọgwụ ụfọdụ, nkezi ọgwụ akara bụ 4.3-4.5 n'ime 5 isi.

Dabere na ndị dọkịta, isi ihe mgbe ị na-eji ngwá ọrụ a bụ ịlele usoro onunu ogwu ma soro ndụmọdụ niile nke dọkịta gị.

A na-ere mbadamba 625 mg (500 mg / 125 mg) na ụlọ ahịa ọgwụ, na nkezi, na 83-85 UAH. Ọnụ ọnụ nke Augmentin mbadamba 875 mg / 125 mg - 125-135 UAH.

Ọnụahịa nkwụsị nke Augmentin maka ụmụaka:
400 mg / 57 mg (Augustmentin 2) - 65 UAH,
200 mg / 28.5 mg - 59 UAH,
600 mg / 42.9 mg - 86 UAH.

Pharlọ ọgwụ n'ịntanetị dị na Russia
Aclọ ahịa ọgwụ n'ịntanetị na UkraineUkraine
Pharmlọ ahịa ọgwụ dị n'ịntanetị na Kazakhstan

Augmentin ntụ ntụ 228.5 mg / 5 ml 7.7 g 70 ml GlaxoSmithKline

Mbadamba Augmentin 250 mg + 125 mg 20 pcs. GlaxoSmithKline

Augmentin ntụ ntụ 642.9 mg / 5 ml 100 ml

Augmentin ntụ ntụ 457 mg / 5 ml 12.6 g 70 ml

Augmentin ntụ ntụ 100 ml GlaxoSmithKline

Augmentin 250mg / 125mg Nke 20 mbadamba SmithKline Beech PiElSi

Augmentin 125mg / 31.25mg / 5ml 100ml ntụ ntụ maka nkwusioru SmithKline Beech PiElSi

Augmentin EU ntụ ntụ maka nkwụsị 600mg + 42.9mg Nke 1 karama GlaxoSmithKline

Augmentin 1000mg Nke 14 mbadamba SmithKline Beecham PiS

Augmentin 200mg / 28.5mg / 5ml 70ml ntụ ntụ maka nkwusioru SmithKline Beech PiElSi

IFlọ ọgwụ IFC

AugmentinSmithKline Beecham, UK

Ọgwụ Augmentin SB (UK)

Augmentin tab. 500mg / 125mg Nke 14 Velcom Foundation GW (UK)

Mpempe akwụkwọ Augmentin BD 625mg Nke 14 Velcom Foundation GW (UK)

Augmentin SRGlaxo Wellcome Production (France)

Augmentin ntụ ntụ maka ịkwadebe usoro ịgba ntụtụ 600mg Nke 10Glaxso Velcom GW (Great Britain)

Pharlọ ọgwụ Pani

Augmentin mgbe ahụ. d / p sirop 228.5mg / 5ml 70ml Glaxo Ọfụma

Augmentin 500 mg / 125 mg Nke 14 tab.p. Smithithline Beecham Pharmaceuticals (UK)

Augmentin 156 mg / 5 ml 100 ml por.d / sirop SmithKline Beecham Pharmaceuticals (UK)

Augmentin 400mg / 57mg / 5ml 35 ml por.d / kwụsị. SmithKline Beecham ọgwụ (UK)

Augmentin 875 mg / 125 mg Nke 14 tabl.smithKline Beecham Pharmaceuticals (Great Britain)

Augmentin 200mg / 28.5mg / 5ml 70 ml por.d / kwụsịtụ. SmithKline Beecham ọgwụ (UK)

Nkọwa dị mkpa maka ya 26.09.2014

Aha Latin: Aha ya bụ Augmentin
Koodu ATX: J01CR02
Arụ Ọrụ: Amoxicillin (Amoxicillin) + Clavulanic acid (Clavulanic acid)
Emeputa: GlaxoSmithKline plc, UK

Na otu mbadamba onụ nwere 0,25, 0,5 ma ọ bụ 0.875 g amoxicillin trihydrate na 0.125 g acid clavulanic(N'ịmepụta ọgwụ ahụ, a na-etinye sodium clavulanate na ngafe 5%).

Agụnyere na ogwu ihe inyeaka: Silicii dioxydum colloidale, magnesium stearate, Carboxymethylamylum natricum, Cellulosum microcrystallicum.

Otu karama ntụ ntụ maka ịkwadebe ya maka injection nwere 0,5 ma ọ bụ 1 g amoxicillin trihydrate na, n'otu n'otu, 0.1 ma ọ bụ 0.2 g acid clavulanic.

Na ntụ ntụ Augmentin EU bu n’obi nkwadebe nke 100 ml nke nkwusiorunwere 0.6 g (5 ml) amoxicillin trihydrate na 0.0429 g (5 ml) acid clavulanic.

Ngwa ihe inyeaka: Silicii dioxydum colloidale, Carboxymethylamylum natricum), Aspartamum (E951), Xanthan gum, Silicii dioxydum, ahihia ahihia 544428.

Na nhazi nke otu Mbadamba ụrọ Augmentin CP na ogologo oge eme ihe gụnyere 1 g amoxicillin trihydrate na 0.0625 g acid clavulanic.

Mpempe mwepụta

Ọgwụ nwere ụdị nnabata ndị a:

Mbadamba Augmentin 250 mg + 125 mg, Augmentin 500 mg + 125 mg na Augmentin 875 + 125 mg.
Powder 500/100 mg na 1000/200 mg, bu n’obi maka nkwadebe nke ihe eji egbu egbu.
Ntụ maka nkwụsị Augmentin 400 mg / 57 mg, 200 mg / 28.5 mg, 125 mg / 31.25 mg.
Ntụ ntụ Augmentin EU 600 mg / 42.9 mg (5 ml) maka nkwusioru.
Augmentin CP 1000 mg / 62.5 mg nwere mbadamba mbugharị ha

Omume ọgwụ

Augmentin bụ ndị otu ọgwụ ọgwụ ọgwụ "ọgwụ antimicrobial maka iji usoro. -lactams. Penicillins. ”

Mmetụta ọgwụ ọgwụ dị ọgwụ nje na ọgwụ nje.

Pharmacodynamics na pharmacokinetics

Idochi anya transpeptidase na imeghari usoro nhazi mureina (akụkụ kachasị mkpa nke mgbidi nke mkpụrụ ndụ nje) n'oge nkewa na uto, ọ na-akpasu iwe nyocha (mbibi) nje.

A na-emebi Amoxicillin -lactamasesya mere ihe ogba-ama ya adighi erute ụmụ njena-arụpụta -lactamases.

Clavulanate na-etolite ogige ejiri rụọ ọrụ -lactamasesnke a na - egbochi mbibi amoxicillin.

Mkpụrụ ọgwụ Augmentin dị irè megide:

Aerobes (+) ikuku: pyogenic streptococcus otu A na B, pneumococci, Staphylococcus aureus na epidermal, (ewezuga ụdị nsogbu methicillin na-eguzogide), staflococcus saprophytic na ndị ọzọ
Ikuku (-) aerobes: Ogwe osisi Pfeiffer, Ukwara-nta, gardnerella vaginalis , cholera vibrio wdg
Gram (+) na gram (-) nke anaerobes: bacteroid, fusobacteria, preotellaswdg
Ihe microorganisms ndị ọzọ: chlamydia, spirochete, treponema paịlị wdg

Mgbe ogwachara Augmentin, ngwa ọrụ ya abụọ na-agbadata ngwa ngwa ma zuo ezu na ngọngọ nri. Ibepu abacha ihe zuru oke ma oburu na ị were ogwu ma obu sirop mgbe iri nri (na nmalite nri).

Abụọ mgbe e jiri ọnụ mee ya, yana iwebata ihe ngwọta nke Augmentin nke anọ, a na-ahụta usoro ọgwụgwọ nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ na akwara niile na mmiri.

Ngwaọrụ abụọ ahụ na-arụ ọrụ ike na-esighi ike protin ọbara nke plasma (ihe ruru 25% jikọrọ protein protein) amoxicillin trihydratena ọ dịghị ihe karịrị 18% acid clavulanic) Achọpụtaghị nchịkọta Augmentin na akụkụ ọ bụla dị n'ime.

Clavulanate site na akụrụ ya na site na usoro ndị ọzọ.

Ihe ngosi maka ojiji

Ihe ngosiputa maka ojiji amoxicillin trihydrate na acid clavulanic bụ na-efe efemkpasu iwe banyere ihe ndia ụmụ nje.

Anabatakwa ọgwụgwọ Augmentin. na-efe efeihe omume rụpụtara ụmụ njenwee mmetụta ọsọ ọsọ na-arụ ọrụ amoxicillinyana agwakọta na-efe efekpasuru ya iwe nje ndị nje amorelere na nje ndị na-emepụta β-lactamaseọ na-eji uche mara ya na ngwakọta nke ọgwụ ọgwụ nọ n'ọrụ.

Na Internetntanetị, a na-ajụkarị ajụjụ “Kedu mkpụrụ mbido Augmentin? "Ma ọ bụ" Gịnị bụ Augmentin Syrup Curing? ".

Okirikiri nke ọgwụ a sara mbara. Edere ya na ihe ndị a ọrịa na-efe efe na mkpali:

na na-efe efena-emetụta elu na ala iku ume ala (gụnyere gụnyere Ọrịa ENT),
na na-efe efena-emetụta ọnya mkpụrụ ndụ,
na odontogenic (onu n’onu) oria,
na ọrịa gynecological,
na ọgbụgba,
na na-efe efena-emetụta anụ ahụ na anụ ahụ dị nro,
na na-efe efena-emetụta anụ ahụ(gụnyere ma ọ bụrụ na ọ dị mkpa, nhọpụta nke onye ọrịa ogologo oge),
ihe ndi ozo na-efe efe ụdị agwakọta (dịka ọmụmaatụ ẹphe tụko iphena sepsis n'oge nke ọmụmụ, na ọrịa mbufụt (sepsis na-enweghị metastases), peritonitisna sepsiskpatara ọrịa intraabdominalna na-efe efena-emepe emepe ihe ogwugwo).

Ihe ngbanwe

Augmentin n'ụdị usoro onunu ogwu ka contraindicated:

ndị ọrịa nwere ọgwụ mgbochi otu ma ọ bụ akụkụ abụọ nke ọgwụ ahụ, nye onye ọ bụla n'ime ya, yana -lactam (i.e. to ọgwụ nje site na otu penisilini na cephalosporin),
ndị ọrịa nwetagogola usoro ọgwụgwọ Augmentin jaundice ma ọ bụ akụkọ banyere arụ ọrụ imeju n'ihi ojiji nke ngwakọta nke ihe ndị na-arụ ọrụ nke ọgwụ ahụ.

Mgbakwunye mgbochi ọzọ na nhọpụta ụrọ maka nkwadebe nke nkwusioru ọnụ yana iji ọgwụ nke ihe arụ ọrụ 125 + 31.25 mg bụ PKU (phenylketonuria).

A na-egbochi ntụ ntụ iji kwadebe nkwusioru nke ọnụ na-eji ya eme ihe (200 + 28.5) na (400 + 57) mg:

na PKU,
ndị ọrịa nwere nsogbu akụrụna nke egosiReberg nwale n'okpuru 30 ml kwa nkeji
ụmụaka na-erubeghị afọ atọ.

Mgbakwunye ọzọ maka iji mbadamba nkume nwere ọgwụ ihe eji eme ihe (250 + 125) na (500 + 125) mg bụ afọ n'okpuru afọ iri na abụọ na / ma ọ bụ ibu na-erughị kilogram 40.

Mbadamba ọgwụ nwere ọgwụ ike 875 + 125 mg na-egbochi ọgwụ:

mebie ọrụ arụmọrụ akụrụ (ndị na-egosi Reberg nwale n'okpuru 30 ml kwa nkeji)
ụmụaka na-erubeghị afọ iri na abụọ
ndị ọrịa nke ịdị arọ ya anaghị agafe 40 n'arọ.

Nsonaazụ

Nsonaazụ nke Augmentin nwere ike ime site na sistemụ na akụkụ mmadụ dị iche iche. Ọtụtụ mgbe, megide ndabere nke ọgwụgwọ ọgwụ, enwere ike ibute mmeghachi omume ndị a:

candidiasis (thrush)akpụkpọ ahụ na akpụkpọ anụ mucous,
afọ ọsịsa(oge niile - mgbe ị na-ewere Augmentin na mbadamba, oge ụfọdụ mgbe ị na -ekwụsịtụ ma ọ bụ na-abanye ọgwụ ahụ),
ọgbụgbọ na ọgbụgbọ (ọgbụgbọ na-abụkarị mgbe ị na-a theụ ọgwụ ahụ na oke doses).

Mmetụta ọghọm ọ na-erite na-enweghị oge ịgụnye:

anya ntughari,
isi ọwụwa,
dysfunctions mgbaze,
mmụba dị nta na ọrụ enzyme imeju omarnine transaminases (ALT)na asmitate transaminases (AST),
akpukpo aru, akpụkpọ anụ?ekpughere urticaria.

N'ọnọdụ ndị a na-adịghị ahụkebe, ahụ nwere ike ịzaghachi nnabata nke Augmentin:

atụgharị leukopenia (gụnyere gụnyere agranulocytosis),
thrombocytopenia,
mmepe thrombophlebitis n’ebe a na-agba ya ọgwụ
polymorphic erythema.

Ọ dịkarịghị ike ịmalite:

hemolytic anaemia,
ọnọdụ e ji mmụba na-egbu oge ọbara ọgbụgba na abawanye ntụpọ prothrombin,
mmeghachi omume sitere na na dịghịzi usoronke egosiri dika angioedema, ọrịa nke yiri nke ahụ gosipụtara ọrịa ọbara, anafilaisis, nfụkasị vasculitis,
hyperactivity ụdị enwere ike ịgbanwe
abawanye ihe omimi,
pricksn'ihi nnabata ọgwụ njegụnyere gụnyere pseudomembranous (PMK) na ọbara ọgbụgba (enwere ike itolite nke ikpe-azụ na-ebelata ma ọ bụrụ na a na-achịkwa Augmentin parenterally),
keratinization na uto nke papillae udi nwere ire (oria akporo 'asusu nwere ntutu'),
ịba ọcha n'anya na cholestasis intrahepatic,
Ọrịa Lyell,
juputara na pustulosis na-ahụ anyan'ụdị siri ike
interstitial nephritis,
Ngosipụta na mmamịrị nke kristal nnu (kristalia).

Bụrụ na nke ọ bụla ọrịa akpịrị A ga-akwụsị ịgwọ ọrịa nfụkasị Ọdụdọ Augmentin.

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Nke mbu, o na - enye nnabata ha nma nma Ọkpụkpụ afọ, na nke abuo, o nwere ike belata oke ihe obula eriri afọ dyspeptikọ bụrụ na nke ikpeazụ bụ ikpe.

Etu ị ga-esi gbakọọ ọgwụ Augmentin

Oge ọ na-anọ n’ọgwụ na-adabere n’otú ahụ onye ọrịa si emeghachi omume na ọgwụgwọ.

Mbadamba Augmentin: ntuziaka maka ojiji

Dabere na ọdịnaya nke ihe ndị na-arụ ọrụ n'ime ha, a na-atụ aro mbadamba Augmentin maka ndị ọrịa toro etozi dịka atụmatụ na-esote:

Augmentin 375 mg (250 mg + 125 mg) - otu ugboro atọ n'ụbọchị. N'ime usoro ogwu a, a na-egosi ọgwụ ahụ maka na-efe efenke ahụ na-abata mfe ma obu udi aru ike. N'ihe banyere ọrịa siri ike, gụnyere ọrịa na-adịghị ala ala na oge nlọghachi, a na-enye usoro ọgwụgwọ dị elu.
Mbadamba mbadamba 625 (500 mg + 125 mg) - otu ugboro atọ n'ụbọchị.
Mbadamba 1000 mg (875 mg + 125 mg) - otu ugboro abụọ n'ụbọchị.

Ogwu a dabere na ndị ọrịa nwere arụmọrụ arụmọrụ. akụrụ.

A na-anabata Augmentin CP 1000 mg / 62.5 mg mbadamba mbugharị ndị ọrịa maka ndị ọrịa karịrị afọ 16. Ihe kachasị mma bụ mbadamba abụọ ugboro abụọ n'ụbọchị.

Ọ bụrụ na onye ọrịa enweghị ike ilo mbadamba ihe niile, o kewara abụọ na ụzọ adịghị mma. A na-ewere halves abụọ n'otu oge.

Ntụ ntụ maka iji gwọọ ntụtụ: ntuziaka maka ojiji

Ọ bụrụ na echere na arụmọrụ ahụ ga-ewe ihe karịrị otu elekere, ruo ihe onunu anọ nke 1000 mg / 200 mg ka a na-enye onye ọrịa ahụ n’ụbọchị gara aga maka awa 24.

Nkwụsị Augmentin: ntuziaka maka ojiji

Taa, ọgwụ n'ụdị usoro dịgasị iche iche bụ otu n'ime ndị akachasị idebere maka ọgwụgwọ. ọnya afọ.

Ọzọkwa, ha na-ejikarị nhọpụta nke Augmentin sinusitis. A na-agbakwunye ọgwụgwọ a site na iji nnu nnu n'oké osimiri na-ehicha imi na iji spalys nke nasal Rinofluimucil. Usoro kachasị mma maka sinusitis: 875/125 mg 2 ugboro n'ụbọchị.Oge ihe ọmụmụ ahụ na-abụkarị 7 ụbọchị.

Dodoụbiga ya ókè

Ceedgafe ogo nke Augmentin na-eso:

mmepe nke imebi site na ngwe nri,
imebi nguzo nke nnu-mmiri,
kristalia,
gbasara akwara,
ọdịda (ọdịda) nke amoxicillin na urinary catheter.

Mgbe mgbaàmà ndị dị otú ahụ pụtara, a na-egosi onye ọrịa n'ọrịa nkwarụ, gụnyere, n'etiti ihe ndị ọzọ, mgbazi nke nguzozi-nnu mmiri. Dradọrọ Augmentin si kanhazi usoro na-emekwa ka usoro a dịrị ịba ọcha n'anya.

Mmekorita

na-enyere aka belata tubular secretion nke amoxicillin,
na-akpalite mmụba nke ịta amoxicillin n'ime ọbara plasma (mmetụta ahụ dịruru ogologo oge),
anaghị emetụta Njirimara na ọkwa nke ọdịnaya plasma nke clavulanic acid.

Ọgwụ a ekwekọghị n'ihe ngwaahịa ọbara na mmiri nwere protein, gụnyere gụnyere whey protein hydrolysates na abụba emulsion chọrọ itinye n’ime akwara.

Usoro ahia

Ọnọdụ nchekwa

Exbọchị mmebi

Ọ dị mma maka iji n'ime afọ 2 site na ụbọchị a rụpụtara.

Analogs nke Augmentin

Analogs Augmentin bụ ọgwụ A-Klav-Farmeks, Amoxiclav, Amoxil-KBetaclava Clavamitin, Medoclave, Teraclav.

Nke ọ bụla n'ime ọgwụ ndị dị n'elu bụ ihe Augmentin nwere ike dochie ya na enweghị ya.

Ọnụahịa analogues dị iche iche site na 63.65 ruo 333.97 UAH.

Augmentin maka ụmụaka

Maka umuaka ọgwụ njena-akọwakarị maka akpịrị mgbu. A na-ekpebi usoro onyonye nke ụmụaka ahụ site afọ na ibu. A na-eke oke elele dị ka onyonyo abụọ, nke hà 45 mg / n'arọ kwa ụbọchị, ma ọ bụ ekewa atọ, usoro nke 40 mg / kg kwa ụbọchị.

Etu ị ga-esi theụọ ọgwụ ahụ maka ụmụaka yana ugboro ole usoro onunu ogwu dabere na usoro usoro onunu ogwu enyere.

Maka umuaka nke aru ha kariri 40 n'arọ, ka edeputara Augmentin otu ogwu ahu dika ndi oria okenye.

A na-eji Augmentin sirop maka ụmụaka ruo otu afọ na dosages nke 125 mg / 31.25 mg na 200 mg / 28.5 mg. Ekwuputara ọgwụ ọnụọgụ 400 mg / 57 mg maka ụmụaka karịrị otu afọ.

Aremụaka nọ n’agbata afọ isii na isii ruo iri isii (ihe dị ka kilogram 19) na-ahapụ ka ha depụta ma nkwusioru yana Augmentin na mbadamba. Usoro onunu ogwu nke udiri ogwu a di otu a:

otu mbadamba 250 mg + 125 mg ugboro atọ n'ụbọchị,
otu mbadamba 500 + 125 mg ugboro abụọ n'ụbọchị (ụdị usoro a bụ ezigbo).

Edebere ụmụaka gafere afọ 12 ka ha were otu mbadamba ụrọ nke 875 mg + 125 mg ugboro abụọ n'ụbọchị.

Ihe atụ nke Augmentin, nke bụ ọgwụ ya, bụ ọgwụ Amoxiclav, Flemoklav Solutab, Arlet, Rapiclav, Ecoclave.

Mmanya ndakọrịta

Augmentin na mmanya abụghị ndị na-emegide ya n'okpuru ị ofụ mmanya na-aba n'anya ọgwụ njeanaghị agbanwe Njirimara ọgwụ ya.

Ọ bụrụ n’ịzụlite usoro ọgwụgwọ ọgwụ ọjọọ, ọ dị mkpa ị drinkụ mmanya, ọ dị mkpa ịlele ọnọdụ abụọ: imeru ihe n’ókè na ịdị nfe.

Maka ndị na-arịa ị alcoholụbiga mmanya ókè, ị simụ ọgwụ ahụ n'otu oge iji mmanya nwere ike ịnwe nsonaazụ ka njọ.

Ya mere, iji zere ihe ize ndụ na-ezighi ezi, a na-atụ aro ka ịhapụ ị alcoholụ mmanya n'oge oge ịgwọ ya na ọgwụ ahụ.

Augmentin n'oge afọ ime na lactation

Ọzọkwa, teratogenic mmetụta adịghị na ma parenteral ma nchịkwa nke ọgwụ.

Ojiji nke Augmentin n'ime ụmụ nwanyị dị ime nwere ike iduga mmepe nke nwa amụrụ ọhụrụ necrotizing enterocolitis (NEC).

Nyocha banyere Augmentin

N'ọmụmụ ihe ebe ndị mmadụ na-ekwupụta mmetụta ha banyere ọgwụ ụfọdụ, nkezi ọgwụ akara bụ 4.3-4.5 n'ime 5 isi.

Dabere na ndị dọkịta, isi ihe mgbe ị na-eji ngwá ọrụ a bụ ịlele usoro onunu ogwu ma soro ndụmọdụ niile nke dọkịta gị.

Ọnụahịa Augmentin

Ọnụahịa Augmentin na Ukraine dịgasị iche dabere na ụlọ ahịa ọgwụ akọwapụtara.N'otu oge ahụ, ọnụ ahịa ọgwụ dị ntakịrị na ụlọ ahịa ọgwụ na Kiev, a na-ere mbadamba nkume na sirop na pharmacies na Donetsk, Odessa ma ọ bụ Kharkov na ọnụ ala dị ala.

A na-ere mbadamba 625 mg (500 mg / 125 mg) na ụlọ ahịa ọgwụ, na nkezi, na 83-85 UAH. Ọnụ ọnụ nke Augmentin mbadamba 875 mg / 125 mg - 125-135 UAH.

Ọnụahịa nkwụsị nke Augmentin maka ụmụaka:
400 mg / 57 mg (Augustmentin 2) - 65 UAH,
200 mg / 28.5 mg - 59 UAH,
600 mg / 42.9 mg - 86 UAH.

Arụ Ọrụ:

Ndị na-ahụ maka ọgwụ

Nhazi ọkwa nosological (ICD-10)

Ihe onyonyo 3D

1 N'ime mmepụta ọgwụ, a na-edobe ọgwụ clavulanate potassium na ngafe 5%.

A na-ewepụ mmiri dị ọcha n'oge mkpuchi ihe nkiri.

Nkọwa nke ụdị usoro onunu ogwu

Omume ọgwụ

Mlọ ọgwụ

Ihe ndị a bụ ọrụ nke ngwakọta nke amoxicillin na clavulanic acid in vitro .

Nje bacteria na-agbakarị ọgwụ ma ọ bụ ngwakọta nke amoxicillin na clavulanic acid

Airabes ọma Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus spp., gụnyere Ihe eji eme plogenes nke okirikiri 1.2, Streptococcus agalactiae 1.2 (beta ọzọ hemolytic streptococci) 1,2, Staphylococcus aureus (chebara methicillin) 1, Staphylococcus saprophyticus (na-emetụta methicillin), coagulase-sta staloloccci (na-emetụta methicillin).

Girata dị mma: Clostridium spp., Peptococcus niger, Peptostreptococcus spp., gụnyere Peptostreptococcus magnus, Peptostreptococcus micros.

Gram-ọjọọ aerobes: Bordetella pertussis, Haemophilus influenzae 1, Helicobacter pylori, Moraxella cafarrhalis 1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.

Gram-ọjọọ anaerobes: Bacteroides spp., gụnyere Bacteroides fragilis, Capnocytophaga spp., Eikenella corrodens, Fusobacterium spp., gụnyere Fusobacterium nucleatum, Porphyromonas spp., Prevotella spp.

Ndị ọzọ: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.

Nje nke bu nje nke nwetara ihe ojoo na nchikota amoxicillin na clavulanic acid nwere ike idi

Gram-ọjọọ aerobes: Escherichia coli 1, Klebsiella spp., gụnyere Klebsiella oxytoca, Klebsiella poniaoniae 1, Proteus spp., gụnyere Proteus mirabilis, Proteus vulgaris, Salmonella spp., Shigella spp.

Airabes ọma Corynebacterium spp., Enterococcus faecium, Streptococcus pneumoniae 1,2 otu na - arụ ọrụ Idmụ nje.

Nje bacteria na -eche na -echeta njikọta nke amoxicillin na clavulanic acid

Gram-ọjọọ aerobes: Acinetobacter spp., Citrobacter freundii, Enterobacter spp., Hafnia alvei, Legionella pneumophila, Morganella morganii, Providencia spp., Pseudomonas spp., Serratia spp., Stenotrophomonas maltophilia, Yersinia enterocolitica.

Ndị ọzọ: Chlamydia spp, gụnyere Chlamydia pneumoniae, Chlamydia psittaci, Coxiella burnetii, Mycoplasma spp.

1 Maka ụmụ nje ndị a, a gosipụtara arụmọrụ ọgwụgwọ nke amoxicillin na clavulanic acid na ọmụmụ ụlọ ọgwụ.

2 Usoro nje nke ụdị nje a anaghị arụpụta beta-lactamase. Ihe mmetụta uche na amoxicillin monotherapy na-atụ aro uche yiri nke a na njikọta nke amoxicillin na clavulanic acid.

Mlọ ọgwụ

Mpempe ọgwụ pharmacokinetic nke bụ isi

Augmentin ®, mg mg + 31.25 mg na 5 ml

A na-egosi usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid dị na ọmụmụ dị iche iche n'okpuru, mgbe ndị ọrụ afọ ofufo ahụike dị afọ 2-12 afọ na afọ efu weere Augmentin ®, ntụ ntụ maka nkwụsị ọnụ, 200 mg + 28.5 mg na 5 ml (228) , 5 mg) na nha nke 45 mg + 6.4 mg / kg / ụbọchị, kewara abụọ.

Mpempe ọgwụ pharmacokinetic nke bụ isi

E gosipụtara usoro ọgwụ pharmacokinetic nke amoxicillin na clavulanic acid na ọmụmụ dị iche iche n'okpuru ndị ọrụ afọ ofufo nwere ahụike were otu ọgwụ Augmentin ®, ntụ ntụ maka nkwụsị ọnụ, 400 mg + 57 mg na 5 ml (457 mg).

Mpempe ọgwụ pharmacokinetic nke bụ isi

Thelọ ọgwụ ọgwụ pharmacookinetic nke amoxicillin na clavulanic acid, enwetara n'ọmụmụ ihe dị iche iche, mgbe ndị ọrụ afọ ofufo na-ebu ọnụ na-arịa ọrịa were:

- 1 taabụ. Augmentin ®, 250 mg + 125 mg (375 mg),

- 2 mbadamba Augmentin ®, 250 mg + 125 mg (375 mg),

- 1 taabụ. Augmentin ®, 500 mg + 125 mg (625 mg),

- 500 mg nke amoxicillin,

- 125 mg nke clavulanic acid.

Mpempe ọgwụ pharmacokinetic nke bụ isi

Amoxicillin na nchịkọta nke ọgwụ Augmentin ®

Clavulanic acid n'ime ihe mejupụtara ọgwụ Augmentin drug

Mgbe ị na-a Augụ ọgwụ Augmentin pla, ihe ndị na-enye nsogbu na plasma nke amoxicillin yiri nke ndị na-ahụ maka nchịkwa ọnụ nke amoxicillin hà.

Thelọ ọgwụ ọgwụ pharmacookinetic nke amoxicillin na clavulanic acid, enwetara n'ọmụmụ akwụkwọ dị iche iche, mgbe ndị ọrụ afọ ofufo na-ebu ọnụ na-arịa ọrịa were:

- 2 mbadamba Augmentin ®, 875 mg + 125 mg (1000 mg).

Mpempe ọgwụ pharmacokinetic nke bụ isi

Amoxicillin na nchịkọta nke ọgwụ Augmentin ®

Augmentin ®, 875 mg + 125 mg

Clavulanic acid n'ime ihe mejupụtara ọgwụ Augmentin drug

Augmentin ®, 875 mg + 125 mg

Dịka ọ dị na nchịkwa iv nke ngwakọta nke amoxicillin na clavulanic acid, a na-ahụta ọgwụgwọ amoxicillin na clavulanic acid n'ọtụtụ anụ ahụ na ọnya ọnya dị iche iche (ọnya afọ, ọnya afọ, anụ ahụ, abụba na akwara anụ ahụ, ọnya synovial na peritoneal fluid, fluid, fluid) )

Amoxicillin na clavulanic acid nwere ogo na-esighi ike nke na-ejikọ protein protein. Nnyocha e mere egosiwo na ihe dị ka 25% nke ngụkọta nke clavulanic acid na 18% nke amoxicillin na plasma ọbara na-emetụta protein protein plasma.

N'ime ọmụmụ anụmanụ, enweghị nchịkọta akụkụ nke nkwadebe Augmentin in na anụ ahụ ọ bụla achọtara.

Amoxicillin, dị ka ọtụtụ penisiliniins, na-abanye n'ime mmiri ara. A nwekwara ike ịchọta akụkụ nke clavulanic acid na mmiri ara.Ewezuga enwere ike ịmalite ịrịa ọrịa ọnya ọnya na ọnya mmamịrị, ọnweghị mmetụta ndị ọzọ nke amoxicillin na clavulanic acid na ahụike nke ụmụ a na-enye ara.

Ọmụmụ banyere ọmụmụ ụmụ anụmanụ egosila na amoxicillin na clavulanic acid na-agafe ihe mgbochi placental. Agbanyeghị, ọ nweghị mmetụta dị njọ na nwa ebu n’afọ achọpụtara.

10-25% nke ọgwụ mbu nke amoxicillin bụ nke akụrụ na - eme ka metabolite na - adịghị arụ ọrụ (penisilloic acid). Clavulanic acid bụ metabolized nke ukwuu ruo 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-3H-pyrrole-3-carboxylic acid na amino-4-hydroxy-butan-2-otu ma wepụta ya site na akụrụ Ọkụ afọ, yana ikuku kubie ume n'ụdị carbon dioxide.

Dị ka ọgwụ penicillins ndị ọzọ, amoxicillin na-apụkarị site na akụrụ, ebe a na-ahụ ọgwụ clavulanic acid site na usoro gbasara akụrụ na extrarenal.

Ihe dị ka 60-70% nke amoxicillin na ihe dị ka 40-65% nke clavulanic acid bụ nke akụrụ na-agbanweghị na aka elekere isii mbụ ka emesịrị 1 tebụl. 250 mg + 125 mg ma ọ bụ mbadamba 1 500 mg + 125 mg.

Oge nlekọta probenecid na-eme ka a kwụsịlata amoxicillin, mana ọbụghị clavulanic acid (lee "Mmekọrịta").

Na-egosi Augmentin ®

Akpịrị anụ ahụ na anụ ahụ dị nro na-ebutekarị Staphylococcus aureus 1, pyogenes Streptococcus na umu Bacteroides 1,

Ọkpụkpụ nke ọkpụkpụ na nkwonkwo, dịka osteomyelitis, na-ebutekarị Staphylococcus aureus 1, ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume ịgwọ ọrịa ogologo oge.

1 Ndị nnọchite anya nke ụdị microorganisms akọwapụtara na-emepụta beta-lactamase, nke na-eme ka ha bụrụ ndị na-enweghị mmetụta na amoxicillin (lee. Pharmacodynamics).

Ihe ngbanwe

Maka ụdị usoro usoro onunu ogwu

hyperensitivity na amoxicillin, clavulanic acid, ihe ndị ọzọ dị na ọgwụ ahụ, ọgwụ mgbochi beta-lactam (dịka penicillins, cephalosporins) na anamnesis,

ihe omume gara aga nke jaundice ma ọ bụ ọrụ imeju na-arịa ya mgbe ị na-ejikọkọta ọgwụ amoxicillin na clavulanic acid na akụkọ ntolite.

Ọzọkwa, maka ntụ ntụ maka nkwụsị ọnụ, 125 mg + 31.25 mg

Ọzọkwa, maka ntụ ntụ maka nkwụsị ọnụ, 200 mg + 28.5 mg, 400 mg + 57 mg

arụ ọrụ na-arụ ọrụ na-arụ ọrụ (Cl creatinine erughị 30 ml / min),

afọ ụmụaka ruo ọnwa atọ.

Ihe ọzọ maka mbadamba ihe mkpuchi fim, 250 mg + 125 mg, 500 mg + 125 mg

ụmụaka na-erubeghị afọ 12 ma ọ bụ buru ibu n’arụghị ibu 40 n'arọ.

Ọzọkwa, maka mbadamba ihe mkpuchi fim, 875 mg + 125 mg

arụ ọrụ na-arụ ọrụ na-arụ ọrụ (Cl creatinine erughị 30 ml / min),

ụmụaka na-erubeghị afọ 12 ma ọ bụ buru ibu n’arụghị ibu 40 n'arọ.

Iji nlezianya: arụ ọrụ imeju.

Ime na lactation

Na nyocha nke omumu omumu na anumanu, onu na ochichi nke Augmentin cause emeghi teratogenic.

N'ime otu nnyocha ụmụ nwanyị nwere membranes akatabeghị aka, achọpụtara na ọgwụ prophylactic na Augmentin be nwere ike ibute oke ihe egwu nke ọrịa enterocolitis n'ime ụmụ amụrụ ọhụrụ. Dịka ọgwụ niile, a naghị atụ aro Augmentin use maka oge ọ dị ime, ọ gwụla ma uru a tụrụ anya na nne ga-akarị ihe o nwere ike ibute nwa ebu n’afọ.

Enwere ike iji ọgwụ Augmentin ® mee ihe n’oge a na-enye nwa ara. Ewezuga nke enwere ike ịmalite afọ ọsịsa ma ọ bụ candidiasis nke akpụkpọ ahụ mucous nke oghere a na-ejikọta ya na ntinye ọnya ọnya nke ọgwụ a n'ime mmiri ara, ọ nweghị mmetụta ọjọọ ndị ọzọ hụrụ na ụmụ a na-enye ụmụ ara. N'ọnọdụ mmetụta ọjọọ na ụmụaka ndị na-enye nwa ara, ọ dị mkpa ịkwụsị ị breastụ ara.

Nsonaazụ

Edeputara ihe ojoo ndi a dị n’okpuru dị ka mmebi nke akụkụ ahụ na akụrụngwa na ugboro ole nke ihe omume. A na-ekpebi ugboro ole ihe a mere dịka nke a: ọtụtụ mgbe - ≥1 / 10, mgbe ≥1 / 100 na the na mbido nri, ugboro ugboro - nsogbu nri, ọ na - adịkarị - ọrịa akpịrị na - egbochi ọnya (gụnyere pịgomembranous colitis na ọbara ọgbụgba). Ire "asịrị, eriri afọ, stomatitis, ịkpụcha akwa nke enamel ezé na ụmụaka. Ilekọta onụ na-enyere gị aka ịpụpụ ezé, ebe ọ bụ na ichi ezé ezuru gị.

N'akuku nke imeju na akwara biliary: ugboro ugboro - mmụba dị ala na ọrụ nke AST na / ma ọ bụ ALT. A na-ahụ ihe ịtụnanya a na ndị ọrịa na-anara ọgwụ mgbochi beta-lactam, mana amabeghị ịdị mkpa ya banyere ọgwụ. O siri ike - ịba ọcha n'anya na cholestatic jaundice. A na-ahụ ihe ịtụnanya a na ndị ọrịa na-anara ọgwụgwọ na ọgwụ penicillin na cephalosporins. Mmụba nke bilirubin na alkaline phosphatase.

A na-ahụta mmetụta na-adịghị mma site na imeju ndị ikom na ndị agadi ma nwee ike jikọta ya na ọgwụgwọ ogologo oge. Ọ bụghị obere ụmụaka ka a hụrụ ihe ọjọọ ndị a.

Ihe iriba ama na akara a edepụtara na-eme n’oge ma ọ bụ ozugbo ngwụcha ọgwụgwọ, mana n’ọnọdụ ụfọdụ ha enweghị ike ịpụta ọtụtụ izu mgbe ha mechara ọgwụgwọ ahụ. A na - agbanwegharị ihe ọghọm. Ihe ojoo sitere na imeju nwere ike bụrụ ihe siri ike, n'ọnọdụ ndị a na-adịghị ahụkebe, enwere akụkọ banyere nsonaazụ na-egbu egbu. N'ihe fọrọ nke nta ka ọ bụrụ n'ọnọdụ niile, ndị a bụ ndị ọrịa nwere nnukwu ọnụọgụ mmụta ma ọ bụ ndị ọrịa na-anata ọgwụ nwere hepatotoxic.

Na akpụkpọ anụ ahụ ugboro ugboro - ọnya, itching, urticaria, na-adịkarịghị erythema multiforme, nke ukwu Stevens-Johnson syndrome, necrolysis na-egbu egbu, dermatitis na-enweghị atụ, nnukwu exanthematous pustulosis.

N'ọnọdụ mmeghachi omume nfụkasị anụ ahụ, a ga-akwụsị ịgwọ ya na Augmentin ®.

Site na akụrụ na eriri afọ: dịkarịsịrị ala - nephritis interstitial, crystalluria (lee "overdose"), hematuria.

Mmekorita

A naghị atụ aro iji ọgwụ Augmentin ® na probenecid n'otu oge. Probenecid na-ebelata mmiri nzuzo nke amoxicillin, yabụ, iji ọgwụ ahụ eme ihe n'otu oge Augmentin ® na probenecide nwere ike ibute mmụba na nnọgide n'ọbara nke amoxicillin, mana ọbụghị clavulanic acid.

Penicillins nwere ike belata mkpochapụ nke methotrexate site na ahụ site na igbochi ihe nzuzo nke tubular ya, yabụ ojiji nke Augmentin na methotrexate nwere ike ịbawanye nsí nke methotrexate.

Dị ka ọgwụ ndị ọzọ na-egbochi nje ihe, nkwadebe Augmentin can nwere ike imetụta microflora eriri afọ, na-eduga n'ịbelata nnabata estrogen site na eriri afọ yana mbelata ịdị irè nke ọgwụ mgbochi ọnụ.

Akwukwo a na - akọwa okwu banyere obere mmụba na MHO n'ime ndị ọrịa yana jikọtara ọnụ nke acenocumarol ma ọ bụ warfarin na amoxicillin. Ọ bụrụ na ọ dị mkpa, ekwesịrị iji nlezianya nyochaa nhazi nke Augmentin ® na PV anticoagulants ma ọ bụ MHO mgbe ị na-ede ma ọ bụ kagbuo nkwadebe Augmentin;; ịhazigharị usoro ọgwụ anticoagulants maka nchịkwa ọnụ.

Usoro onunu ogwu na nhazi

Usoro usoro onunu ogwu ka edobere n’otu n’otu, dabere n’afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji belata nsị nke oghere ga-ekwe omume na iwelata ohere ị ,ụ mmanya, a ga-a drugụ ọgwụ ahụ na mbido nri. Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, a ga - enwe ike ịme ọgwụgwọ na - aga ije (usoro nchịkwa mbụ nke ọgwụ ahụ na ntinye ga - esote ya na nchịkwa ọnụ).

Ekwesịrị icheta ya na taabụ 2 ahụ. Augmentin ®, 250 mg + 125 mg ezughị 1 mbadamba. Augmentin ®, 500 mg + 125 mg.

Taabụ 1. 500 mg + 125 mg ugboro atọ n'ụbọchị.

Taabụ 1. 875 mg + 125 mg 2 ugboro n'ụbọchị.

Usoro Augmentin s usoro onunu ogwu (gbakọọ agbakọọ dabere na amoxicillin)

A na-atụ aro iji obere Augmentin ® maka ọgwụgwọ nke ọrịa anụ ahụ na anụ ahụ dị nro, yana tonsillitis ugboro ugboro.

Umu amuru n’azu. Enweghị ntuziaka maka usoro usoro usoro onunu ogwu.

Ndị otu ọrịa pụrụ iche

Ndị ọrịa nwere ọria imeju. A na- eji nlezianya na-agwọ ọgwụgwọ; a na-enyocha ọrụ imeju. Enweghi data zuru oke iji gbanwee ntuziaka maka ọgwụ ndị ọrịa dị otú ahụ.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu. Ntuzi nke usoro onunu ogwu sitere na oke agbadoro anya nke amoxicillin na uru ikike idozi.

Usoro Augmentin ® usoro onunu ogwu

Mbadamba ihe eji etinye fim, 250 mg + 125 mg: mmeghari onunu ogwu dabere na oke okacha amara nke amoxicillin.

2 taabụ. 250 mg + 125 mg na 1 dose kwa awa 24

N'oge nnọkọ omalụ a, ihe ọzọ 1 (1 mbadamba) na mbadamba 1 ọzọ. na njedebe nke nnọkọ omalụ (iji kwụọ ụgwọ mbelata nke serum nke amoxicillin na clavulanic acid).

Mbadamba ihe eji etinye fim, 500 mg + 125 mg: mmeghari onunu ogwu dabere na oke okacha amara nke amoxicillin.

Taabụ 1. 500 mg + 125 mg na 1 dose kwa awa 24

N'oge nnọkọ omalụ a, ihe ọzọ 1 (1 mbadamba) na mbadamba 1 ọzọ. na njedebe nke nnọkọ omalụ (iji kwụọ ụgwọ mbelata nke serum nke amoxicillin na clavulanic acid).

Ofzọ nkwadebe nke nkwusioru

Maka umuaka n’agbata afo abuo, ihe omuma nke ntughari ogwu Augmentin ® nwere ike with jiri mmiri rita 1: 1.

Dodoụbiga ya ókè

Ọrịa enwere ike ihu ya site na eriri afọ na ọgba aghara na mmiri-electrolyte.

A kọwara amoxicillin crystalluria, n'ọnọdụ ụfọdụ na - eduga na mmepe nke ọdịda akwara (lee "Ntuziaka Pụrụ Iche").

Ọrịa dị na ndị ọrịa nwere nsogbu gbasara akụrụngwa, yana ndị na-anata oke ọgwụ.

Ọgwụgwọ: Mgbaàmà sitere na akwara afọ - ọgwụgwọ ọrịa, na-a ,a ntị pụrụ iche na nhazi mmiri. Enwere ike wepu Amoxicillin na clavulanic acid na ọbara ọbara site na hemodialysis.

Nsonaazụ nke ọmụmụ ihe a na-ele anya nke emere ya na ụmụ 51 n'ime ebe a na-egbu egbu gosipụtara na nchịkwa nke amoxicillin na ọgwụ erughị 250 mg / n'arọ anaghị eduga mgbaàmà dị egwu ma ọ chọghị lavage gastric.

Ntụziaka pụrụ iche

Tupu ịmalite ọgwụgwọ na Augmentin ®, ọ dị mkpa ịnakọta akụkọ banyere ahụike zuru ezu gbasara mmerụ ahụ gara aga banyere penicillins, cephalosporins ma ọ bụ ihe ndị ọzọ na-akpata mmeghachi omume nfụkasị n'ime onye ọrịa.

A kọwara mmeghachi omume dị njọ na mgbe ụfọdụ na-egbu mmụọ (anaphylactic reactions) na penisilini. Ihe ọghọm nke mmeghachi omume dị otú a bụ nke kachasị elu na ndị ọrịa nwere akụkọ banyere hypersensitivity hypersensitivity penicillins. Maka mmeghachi omume nfụkasị ahụ, ọ dị mkpa ịkwụsị ọgwụgwọ na Augmentin ® wee malite usoro ọgwụgwọ ọzọ kwesịrị ekwesị.

N'ihe banyere mmeghachi omume anaphylactic siri ike, e kwesịrị inye onye ọrịa ọgwụ epinephrine ozugbo. Oxygen therapy, ochichi nke GCS na inye nke patway ikuku, gụnyere intubation, nwekwara ike choro.

Ọ bụrụ na inyo enyo na mononucleosis na-efe efe, ekwesighi iji Augmentin ®, ebe ọ bụ na ndị ọrịa nwere ọrịa a, amoxicillin nwere ike ibute ọnya akpụkpọ ahụ, nke na-agbagha nchọpụta nke ọrịa ahụ.

Ọgwụ ogologo oge na Augmentin ® nwere ike iduga ịmụba oke nke microorganisms na-enweghị nsogbu.

Na mkpokọta, Augmentin ® na-anabata nke ọma ma nwee agwa ọjọọ nwere ụdị penicillins niile. N'oge ọgwụgwọ ogologo oge na Augmentin ®, a na-atụ aro ka inyocha ọrụ akụrụ, imeju na hematopoiesis oge oge.

Iji belata ihe egwu dị na nsị eriri afọ, a ga-a theụ ọgwụ ahụ na mmalite nri.

N'ime ndị ọrịa na-anakọta ngwakọta nke amoxicillin na clavulanic acid yana anticoagulants na-apụtachaghị ọnụ (n'ọnụ), n'ọnọdụ ndị a na-adịghị ahụkebe, mmụba nke PV (mmụba na MHO). Site na ntinye njikọta nke anticoagulants na-apụtachaghị ọnụ (ọnụ) yana ngwakọta nke amoxicillin na clavulanic acid, nleba anya nke ihe ndị dị mkpa dị mkpa. Iji nọgide na-enwe mmetụta ọgwụ anticoagulants chọrọ, a pụrụ ịchọ ndozi usoro usoro ọgwụgwọ.

N'ime ndị ọrịa nwere nsogbu gbasara akụrụngwa nsogbu, a ga-enye ọgwụ ọgwụ Augmentin according dị ka ogo nke imebi (lee “Usoro ọgwụgwọ na nchịkwa”), Ndị ọrịa nwere ọrụ mgbazinye nsogbu).

N'ime ndị ọrịa nwere ọrịa diuresis, ọrịa kristal na-adịkarị obere, ọ kachasị na usoro ọgwụgwọ oge. N'oge nchịkwa nke oke ọgwụ nke amoxicillin, a na-atụ aro ka ị takeụọ mmiri zuru ezu ma na-edozi diureis zuru oke iji belata ohere nke ịmepụta kristalillin kristal (lee “doụbiga ihe ókè”).

Iburu ọgwụ Augmentin ® n'ime na-eduga n'inwe afọ ojuju nke amoxicillin na mmamịrị, nke nwere ike ibute nsonaazụ ụgha na mkpebi siri ike nke glucose na mmamịrị (dịka ọmụmaatụ, nnwale Benedict, ule Feling). N'okwu a, a na-atụ aro iji usoro glucose oxidant maka ikpebi mkpokọ glucose na mmamịrị.

Nkuzi onu na-enyere gi aka ichoputa nha nke eze na ị withụ ọgwụ, ebe o zuru ezu ịhapụ ezé gị (maka nkwụsị).

Ọ dị mkpa iji ọgwụ ọgwụ Augmentin ® n'ime ụbọchị iri atọ site na mgbe imepe ngwugwu nke lail aluminom foil (maka mbadamba)

Abụbiga ọgwụ ike na ịenceụ ọgwụ. Achọpụtaghị ị dependụ ọgwụ, ọgwụ riri ahụ na mmeghachi omume anụ ahụ metụtara iji ọgwụ Augmentin ®.

Mmetụta ikike ịkwọ ụgbọ ala ma jiri usoro rụọ ọrụ. Ebe ọgwụ ahụ nwere ike ibute ọgbụgba, ọ dị mkpa ịdọ ndị ọrịa aka na ntị banyere ị ga-akpachara anya mgbe ị na-anya ụgbọala ma ọ bụ na-arụ ọrụ igwe na-akpụ akpụ.

Mpempe mwepụta

Ntụ ntụ maka nkwụchi ọnụ, 125 mg + 31.25 mg na 5 ml. N'ime karama doro anya, kpuchie ya na okpu mkpuchi alumini nwere njikwa nke oghere mbụ, 11.5 g 1 fl. ya na okpu eji atunye ihe na kaadiboodu.

Ntụ ntụ maka nkwụsị ọnụ, 200 mg + 28.5 mg na 5 ml, 400 mg + 57 mg na 5 ml. Na karama enyo enyo mechiri emechi mkpuchi alumini ahu nke nwere ikike imeghe mbu, 7.7 g (maka onunu ogwu nke 200 mg + 28.5 mg na 5 ml) ma obu 12.6 g (maka onunu ogwu nke 400 mg + 57 mg na 5 ml ) 1 fl. tinyere okpu eji atụ ma ọ bụ sirinji na igbe kaadi.

Mbadamba ihe eji etinye fim, 250 mg + 125 mg. Na aluminom / PVC ọnya mkpụrụ 10 pcs. 1 ọnya na akpa nke silica na ngwugwu nke aluminium laminated. Mpempe akwụkwọ 2 mkpọ na igbe kaadi.

Mbadamba ihe eji etinye fim, 500 mg + 125 mg. Na aluminom / PVC / PVDC ọnya 7 ma ọ bụ 10 PC. 1 ọnya na akpa nke silica na ngwugwu nke aluminium laminated. 2 ngwugwu nke aluminium lavu emere na igbe kaadi.

Mbadamba ihe eji etinye fim, 850 mg + 125 mg. Na aluminom / PVC ọnya 7 pcs. 1 ọnya na akpa nke silica na ngwugwu nke aluminium laminated. Mpempe akwụkwọ 2 mkpọ na igbe kaadi.

Irationbọchị mmechi nke Augmentin

mbadamba ihe mkpuchi fim 250 mg + 125 mg - afọ 2.

mbadamba ihe mkpuchi 500 mg + 125 mg - afọ 3.

mbadamba ihe mkpuchi fim 875 mg + 125 mg - 3 afọ.

ntụ ntụ maka nkwusioru maka nchịkwa ọnụ 125mg + 31.25mg / 5ml - afọ 2. Nkwado a kwadebere bụ ụbọchị asaa.

ntụ ntụ maka nkwusioru maka nchịkwa ọnụ 200 mg + 28.5 mg / 5 ml 200 mg + 28.5 mg / 5 - afọ 2. Nkwado a kwadebere bụ ụbọchị asaa.

ntụ ntụ maka nkwusioru maka nchịkwa ọnụ 400 mg + 57 mg / 5 ml 400 mg + 57 mg / 5 - afọ 2. Nkwado a kwadebere bụ ụbọchị asaa.

Ejila oge emechara ka egosiputara na ngwugwu ahụ.

Mbadamba ihe mkpuchi site na ọcha na ọ fọrọ nke nta na-acha ọcha, oval, na ihe odide a na-ede aha ya bụ “AUGMENTIN” n'otu akụkụ, na kink - site na ọcha na-acha ọcha ruo ihe fọrọ nke nta ka ọ bụrụ ọcha.

Ndị pụrụ icheMagnesium stearate 6.5 mg, sodium carboxymethyl stachi 13 mg, colloidal silicon dioxide 6.5 mg, microcrystalline cellulose 650 mg.

Ihe ndị mejupụtara ihe nkiri ahụ: titanium dioxide - 9.63 mg, hypromellose (5cP) - 7.39 mg, hypromellose (15cP) - 2.46 mg, macrogol 4000 - 1.46 mg, macrogol 6000 - 1.46 mg, dimethicone - 0.013 mg, mmiri dị ọcha (wepụrụ n'oge mmepụta).

10 PC. - blisters (1) ya na akpa nke silica gel - ihe eji eme ya na alumini achara (2) - ngwugwu nke kaadiboodu.

Nje virus nke bakteria na-akpata:

- gonorrhoea nke Neisseria gonorrhoeae * kpatara (ma e wezụga mbadamba 250 mg / 125 mg),

- ofufe ọrịa nke anụ ahụ na anụ ahụ dị nro, nke a na-ebutekarị site na Staphylococcus aureus *, Streptococcus pyogenes na ụdị mkpụrụ ndụ ihe nketa Bacteroides *,

- Ọrịa nke ọkpụkpụ na nkwonkwo: osteomyelitis, nke Staphylococcus aureus na - akpata ya, ọ bụrụ na ọ dị mkpa, ogologo oge ọgwụgwọ,

- ọrịa odontogenic, dịka ọmụmaatụ, periodontitis, maxillary sinusitis, ọnya eze siri ike na mgbasa cellulite (maka mbadamba 500 mg / 125 mg ma ọ bụ 875 mg / 125 mg),

* - ndị nnọchite anya nke ụdị microorganisms akọwapụtara na-emepụta β-lactamase, nke na-eme ka ha bụrụ ndị na-enweghị mmetụta na amoxicillin.

Ọrịa Augmentin be nwere ike ịgwọ ọrịa ndị microorganisms na-emetụta amoxicillin, ebe ọ bụ na amoxicillin bụ otu n'ime ihe ndị dị na ya.Augmentin ® ka egosiri maka ọgwụgwọ nke ọrịa nje jikọtara nke microorganisms nke nwere amoxicillin, yana microorganisms na-emepụta β-lactamase, na-emetụta nchikota nke amoxicillin na clavulanic acid.

A na-edobe usoro usoro onunu ogwu n'otu oge dabere na afọ, oke ahụ, ọrụ akụrụ nke onye ọrịa, yana ogo ọrịa ahụ.

Iji were mee nke ọma ma belata nsonaazụ ndị enwere ike na sistemụ nri, a na-atụ aro Augmentin ® ka ị malite nri.

Obere oge nke ọgwụ mgbochi bụ ụbọchị 5.

Ọgwụ ekwesịghị ịga n’ihu karịa ụbọchị iri na anọ na-enweghị nyocha banyere ọnọdụ ụlọ ọgwụ.

Ọ bụrụ na ọ dị mkpa, ọ ga-ekwe omume duziri ọgwụ (na mmalite ọgwụgwọ, parenteral management of the ọgwụ with sochiri transition to oral management).

Ndị okenye na ụmụaka karịrị afọ 12 ma ọ bụ na-eru 40 n'arọ ma ọ bụ karịa

Mbadamba 2 nke 250 mg / 125 mg ezughị 1 mbadamba 500 nke 500 mg / 125 mg.

Umuaka site na onwa ato rue afo iri na abuo n’ariri aru ha erughi kilogram 40

Edere ọgwụ ahụ n'ụdị nkwusioru maka nchịkwa ọnụ.

A na-eme ngụkọta oge dabere na afọ na oke ahụ, nke egosipụtara na mg / kg body body / day (ịgbakọ dịka amoxicillin) ma ọ bụ na ml nke nkwusioru.

Otutu nke iwere ihe na-anakpo 125 mg / 31.25 mg na 5 ml bụ ugboro 3 / ụbọchị kwa awa asatọ.

Otutu nke nkwusioru 200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml - 2 ugboro / ụbọchị kwa awa 12 ọ bụla.

Usoro usoro usoro onunu ogwu a ka akwadoro ka ana egosiputa ya na oge oru ya na tebulu di n'okpuru.

Tebụl Augmentin s usoro onunu ogwu (onodu ogwu maka amoxicillin)

Obere onunu Augmentin ® ka eji ọgwụgwọ nke ọrịa akpụkpọ na anụ ahụ dị nro, yana ọrịa otill na-eme ugboro ugboro.

A na-eji ọgwụ ọgwụ Augmentin High dị elu na-agwọ ọrịa ndị dị ka otitis media, sinusitis, ọrịaỌkpụkpụ akụkụ iku ume yana akwara na -akpata ọkpụkpụ na nkwonkwo.

Ezighi nyocha ụlọ ọgwụ ezighi ezi iji kwado ọgwụ ọgwụ Augmentin ® na ọgwụ nke karia 40 mg / kg / ụbọchị na usoro 3 kewara (4: 1 nkwusioru) ụmụaka na-erubeghị afọ 2.

Umuaka site na omumu rue onwa ato

N'ihi ezumike nke akụrụ ahụ, ọgwụ a tụrụ aro ya nke Augmentin ® (gbakọọ maka amoxicillin) bụ 30 mg / n'arọ / ụbọchị n'ime usoro 2 nke 4: 1.

Ekwesighi iji nkwusioru 7: 1 (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml) akwadoghị na ọnụ ọgụgụ a.

Umu aka

Enweghị ntuziaka maka usoro usoro usoro onunu ogwu.

Ndị okenye na-arịa ọrịa

Odighi ndozi uzo a choro. Na ndị ọrịa agadi nwere ọrụ ezumike ọrụ ọ kwesịrị idozigharị ọgwụ a dị ka ndị a maka ndị okenye nwere ọrụ ezumike ọhụrụ.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu

Imeghari usoro a dabere na oke ọgwụ a tụrụ aro ya na amoxicillin ma a na-eburu n'uche n'uche ụkpụrụ QC.

Ndị okenye

N'ọnọdụ ka ukwuu, ọ bụrụ na ọ ga-ekwe omume, a ga-ahọrọ usoro ọgwụgwọ nke ihe na-ahụ maka ọrịa nwa oge.

Ọrịa ịba ọcha n'anya

Ọgwụ n'oge nnọkọ hemodialysis, otu 1 ọzọ (otu mbadamba) na ọgwụ ọzọ (otu mbadamba) na njedebe ngwụsị usoro (iji kwụọ ụgwọ maka mbelata nke serum nke amoxicillin na clavulanic acid).

Nkwụsị tupu oge mmegharị ahụ, a ga-elekọta otu ọgwụ ọzọ nke 15 mg / 3.75 mg / kg. Iji weghachi nchịkọta nke ihe ndị nọ n'ọrụ ọgwụ ọgwụ Augmentin ® n'ọbara, a ga-enyerịrị nkeji abụọ ọzọ nke 15 mg / 3.75 mg / kg mgbe emume hapatialysis gasịrị.

Ndị ọrịa nwere ọria imeju

A na- eji nlezianya na-agwọ ọgwụgwọ; a na-enyocha ọrụ imeju. Enweghi data zuru oke iji dozie usoro usoro onunu ogwu di na ndi otu a.

Iwu maka nkwadebe nke nkwusioru

A kwadebere nkwusioru ya ozugbo tupu ojiji izizi.

Nkwụsị (125 mg / 31.25 mg na 5 ml): Ihe dị ka milimita 60 nke esi esi mmiri ga-eme ka ekpomoku dị n'ime karama ahụ, ma jiri mkpuchi kpuchie karama ahụ ruo mgbe etinyere ntụ ntụ kpamkpam, kwe ka karama ahụ kwụrụ ruo minit 5 iji hụ na ngwakọta zuru ezu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 92 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ accurateụ accurateụ ziri ezi, a ga-eji okpu eji atụ ahụ, nke a ga-eji mmiri wee saa ya nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka ụmụaka na-erubeghị afọ abụọ, enwere ike iji otu mmiri tụọ nkwụchi nke nkwadebe Augmentin ® nwere ọkara wee jiri mmiri mee ya.

Nkwụsị (200 mg / 28.5 mg na 5 ml ma ọ bụ 400 mg / 57 mg na 5 ml): ihe dị ka milimita 40 nke esi esi mmiri ga-eme ka ekpomoku dị n'ime karama ahụ, ma jiri mkpuchi kpuchie karama ahụ ruo mgbe a ga-agwagbu ntụ ntụ ahụ, kwe ka karama ahụ kwụrụ ruo minit 5 iji hụ na ngwakọta zuru ezu. Tinye mmiri n’ime akara n’ime karama ahụ ma gbanye karama ahụ ọzọ. Na mkpokọta, a chọrọ ihe dị ka 64 ml mmiri iji kwadebe nkwusioru. Ekwesịrị imebi karama ahụ nke ọma tupu ojiji ọ bụla. Maka ịsingụ ọgwụ ọ bụla nke ọma, jiri okpu ị na-eji atụ ma ọ bụ sirinji ọnya, nke a ga-eji mmiri wee saa ahụ nke ọma. Mgbe dilution, ekwesịrị ịchekwa nkwụsị ahụ ihe na-erughị ụbọchị 7 na friji, mana ọ bụghị oyi kpọnwụrụ.

Maka ụmụaka na-erubeghị afọ abụọ, a pụrụ iji mmiri tụọ n ’usoro nkwanye ụgwọ emezi emezi Augmentin with site na 1: 1.

Site na akụrụ na eriri afọ: dịkarịsịrị ala - nephritis interstitial, crystalluria, hematuria.

- Hypersensitivity na amoxicillin, clavulanic acid, ihe ndị ọzọ dị na ọgwụ ahụ, ọgwụ mgbochi beta-lactam (dịka penicillins, cephalosporins) na anamnesis,

- ihe ndị mere na jaundice gara aga ma ọ bụ ọrụ imeju na - arụ ọrụ mgbe ị na - ejikọkọta amoxicillin na clavulanic acid na anamnesis,

- afọ ụmụaka rue afọ 12 na ịdị arọ nke ihe na-erughị 40 n'arọ (maka mbadamba 250 mg / 125 mg ma ọ bụ 500 mg / 125 mg, ma ọ bụ 875 mg / 125 mg),

- afọ ụmụaka rue ọnwa atọ (maka ntụ ntụ maka ịkwadebe nkwusioru maka nchịkwa ọnụ nke 200 mg / 28.5 mg na 400 mg / 57 mg),

- ọrụ ezigharị adịghị arụ ọrụ (CC ≤ 30 ml / min) - (maka mbadamba 875 mg / 125 mg, maka ntụ ntụ maka nkwusioru maka nchịkwa ọnụ 200 mg / 28.5 mg na 400 mg / 57 mg),

- phenylketonuria (maka ntụ ntụ maka nkwusioru maka nchịkwa ọnụ).

Na ịkpachara anya: arụ ọrụ imeju.

N'ime omumu banyere omumu umu anumanu, onodu onu na nke ochichi nke Augmentin cause emeghi teratogenic.

N'ime otu nnyocha ụmụ nwanyị nwere membranes akatabeghị aka, achọpụtara na ọgwụ ọgwụ prophylactic nwere ike ịnwe n'ihe egwu dịkwuo elu nke necrotizing enterocolitis n'ime ụmụ amụrụ ọhụrụ.Dị ka ọgwụ niile, a naghị atụ aro Augmentin use maka oge a dị ime, ọ gwụla ma uru a tụrụ anya na nne ga-akarị ihe o nwere ike inweta n’ute nwa.

Enwere ike iji ọgwụ Augmentin ® mee ihe n’oge a na-enye nwa ara. Ewezuga nke enwere ike ịmalite afọ ọsịsa ma ọ bụ candidiasis nke akpụkpọ ahụ mucous nke oghere a na-ejikọta ya na ntinye ọnya ọnya nke ọgwụ a n'ime mmiri ara, ọ nweghị mmetụta ọjọọ ndị ọzọ hụrụ na ụmụ a na-enye ụmụ ara. N'ọnọdụ mmetụta ọjọọ na ụmụaka ndị na-enye nwa ara, ọ dị mkpa ịkwụsị ị breastụ ara.

Ndị ọrịa nwere ọrụ mgbazinye nsogbu

Imeghari usoro a dabere na oke ọgwụ a tụrụ aro ya na amoxicillin ma a na-eburu n'uche n'uche ụkpụrụ QC.

Ndị okenye

N'ọnọdụ ka ukwuu, ọ bụrụ na ọ ga-ekwe omume, a ga-ahọrọ usoro ọgwụgwọ nke ihe na-ahụ maka ọrịa nwa oge.

Ndị okenye na ụmụaka karịrị afọ 12 ma ọ bụ na-eru ihe karịrị 40 n'arọ na hemodialysis

Nhazi dose dabere na oke ọgwụ a tụrụ aro maka amoxicillin: 1 taabụ. 500 mg + 125 mg n'otu ọgwụ kwa awa 24 ma ọ bụ mbadamba abụọ. 250 mg / 125 mg na otu mkpụrụ ọgwụ kwa awa 24, ma ọ bụ 500 mg / 125 mg (20 ml nke nkwusioru na ọgwụ nke mg mg mg / 31,25 na 5 ml) 1 oge / ụbọchị.

N’oge usoro omumu ihe omimi, ihe onwa ozo (otu mbadamba) na mbadamba ihe ozo na ngwucha okwu a (iji kwụọ ụgwọ mbelata nke ihe ogugu nke amoxicillin na clavulanic acid).

Undermụaka n’agbata afọ iri na abụọ

Edere ọgwụ ahụ n'ụdị nkwusioru maka nchịkwa ọnụ.

A na-agbakọ mgbatị ahụ dabere na afọ na ịdị arọ, egosiri na mg / n'arọ nke ịdị arọ ahụ kwa ụbọchị (ngụkọ dịka amoxicillin) ma ọ bụ na nkwụsị nke mililiters.

Weighmụaka dị kilogram 40 ma ọ bụ karịa otu usoro onunu ogwu dika ndi okenye kwesiri ikwenye.

Umuaka site na omumu rue onwa ato. N'ihi ezumike nke akụrụ ahụ, ọgwụ a tụrụ aro ya nke Augmentin ® (gbakọọ maka amoxicillin) bụ 30 mg / n'arọ / ụbọchị n'ime usoro 2 nke 4: 1.

Ekwesighi iji nkwusioru 7: 1 no na onu ogugu a.

Agedmụaka gbara ọnwa atọ ruo afọ iri na abụọ. Usoro usoro usoro onunu ogwu a ka akwadoro ka ana egosiputa ya na oge oru ya na tebulu di n'okpuru.

Tebụl Augmentin s usoro onunu ogwu (onodu ogwu maka amoxicillin)

Obere onunu Augmentin ® ka eji ọgwụgwọ nke ọrịa akpụkpọ na anụ ahụ dị nro, yana ọrịa otill na-eme ugboro ugboro.

A na-eji ọgwụ ọgwụ Augmentin High dị elu na-agwọ ọrịa ndị dị ka otitis media, sinusitis, ọrịaỌkpụkpụ akụkụ iku ume yana akwara.

Enwe data ezughi oke nke ụlọ ọgwụ iji kwado ọgwụ ọgwụ Augmentin ® na nha karịa 40 mg / kg / ụbọchị n'ime usoro 3 kewara (4: 1 nkwusioru) ma ọ bụ 45 mg / kg / ụbọchị na usoro 2 kewara (7 kwụsịtụ) ụmụaka na-erubeghị afọ 2.

Tupu ịmalite ọgwụgwọ na Augmentin ®, ọ dị mkpa ịnakọta akụkọ banyere ahụike zuru ezu gbasara nsogbu hypersensitivity gara aga na penicillins, cephalosporins ma ọ bụ allergens ndị ọzọ.

A kọwara mmeghachi omume dị njọ, na mgbe ụfọdụ ọnwụ, hypersensitivity mmeghachi omume (anaphylactic reactions) na penisilini. Ihe ọghọm nke mmeghachi omume dị otú a bụ nke kachasị elu na ndị ọrịa nwere akụkọ banyere hypersensitivity hypersensitivity penicillins. Maka mmeghachi omume nfụkasị ahụ, ọ dị mkpa ịkwụsị ọgwụgwọ na Augmentin ® wee malite usoro ọgwụgwọ ọzọ kwesịrị ekwesị. N'ihe banyere nzaghachi hypersensitivity siri ike, e kwesịrị inye epinephrine ozugbo. Oxygen therapy, ochichi nke GCS na inye nke patway ikuku, gụnyere intubation, nwekwara ike choro.

A naghị atụ aro ịhọpụta Augmentin drug nke ọgwụ n'ọnọdụ ndị a na-enyo enyo mononucleosis na-efe efe, ebe ọ bụ na ndị ọrịa nwere ọrịa a, amoxicillin nwere ike ibute ọnya dịka ọrịa, nke na-agbagha nchọpụta nke ọrịa ahụ.

Ọgwụ ogologo oge na Augmentin ® na-eduga mgbe ụfọdụ ịmụba ụmụ irighiri ihe na-adịghị mma.

Na mkpokọta, Augmentin ® na-anabata nke ọma ma nwee agwa ọjọọ nwere ụdị penicillins niile.

N'oge ọgwụgwọ ogologo oge na Augmentin ®, a na-atụ aro ka inyocha ọrụ akụrụ, imeju na hematopoiesis oge oge.

Iji belata ihe egwu dị na nsị eriri afọ, a ga-a theụ ọgwụ ahụ na mmalite nri.

N'ime ndị ọrịa nwere nsogbu gbasara akwara nwere nsogbu, ọgwụ Augmentin ® kwesịrị belata ya.

Iburu ọgwụ Augmentin ® n'ime na-eduga n'ọtụtụ ọdịnaya nke amoxicillin na mmamịrị, nke nwere ike ibute nsonaazụ ụgha na mkpebi mkpebi nke glucose na mmamịrị (dịka ọmụmaatụ, nnwale Benedict, nnwale na-agba ọkụ). N'okwu a, a na-atụ aro iji usoro glucose oxidant maka ikpebi mkpokọ glucose na mmamịrị.

Ilekọta onụ na-enyere gị aka ịpụpụ ezé, ebe ọ bụ na ichi ezé ezuru gị.

A ga-eji mbadamba mee ihe n'ime ụbọchị iri atọ site na mgbe imepe ngwungwu nke ngwungwu alumọn dị.

Abụbiga ọgwụ ike na ịenceụ ọgwụ

Achọpụtaghị ị dependụ ọgwụ, ọgwụ riri ahụ na mmeghachi omume anụ ahụ metụtara iji ọgwụ Augmentin ®.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

Ọrịa mgbaàmà eriri afọ na enweghi ikike elele anya mmiri nwere ike ime. A kọwara amoxicillin crystalluria, n'ọnọdụ ụfọdụ na-eduga na mmepe nke ọdịda akwara.

Ọnọdụ nwere ike ịdakwasị ndị ọrịa nwere nsogbu gbasara akụrụ, yana ndị na-anata oke ọgwụ.

Ọgwụgwọ: mgbaàmà eriri afọ - ọgwụgwọ ọrịa, na-elebara ya anya ka ọ dị idozigharị mmiri-electrolyte. Bụrụ na ị anụbiga ihe ọseụ ,ụ, enwere ike wepu amoxicillin na clavulanic acid n'ọbara ọbara site na ịba ama.

Penicillins nwere ike belata mkpochapụ nke methotrexate site na ahụ site na igbochi ihe nzuzo nke tubular ya, yabụ, iji ọgwụ ahụ eme ihe n'otu oge Augmentin ® na methotrexate nwere ike iwelie nsị nke methotrexate.

Akwukwo a na - akọwa okwu banyere obere mmụba na MHO n'ime ndị ọrịa yana jikọtara ọnụ nke acenocumarol ma ọ bụ warfarin na amoxicillin. Ọ bụrụ na ọ dị mkpa iji ọgwụ anticoagulants depụta Augmentin ult n'otu oge, prothrombin oge ma ọ bụ MHO kwesịrị iji nlezianya nyochaa mgbe edepụtara ma ọ bụ kagbuo Augmentin ®, ịchọrọ ịgbanwe mmezi nke ọgwụ anticoagulants maka nchịkwa ọnụ.

Ogwu gi bu ogwu.

Ekwesịrị ịchekwa ọgwụ a na ebe akọrọ na ụmụaka agaghị enweta ya na okpomọkụ na-agaghị akarị 25 Celsius. Ndụ nchekwa nke mbadamba (250 mg + 125 mg) na (875 mg + 125 mg) bụ afọ 2, mbadamba (500 mg + 125 mg) - afọ 3. Ndụ nchekwa nke ntụ ntụ maka ịkwadebe nkwusioru n'ime karama na-emebeghị emeghe bụ afọ 2.

Ekwesịrị ịchekwa nkwusioru a kwadebere na friji na okpomọkụ nke 2 Celsius ruo 8 Celsius maka ụbọchị asaa.

Younwere ọgwụ n cription ụlọ ọgwụ na-ere ọgwụ, ọ nwere ike jụọ ọgwụ maka ya!

AUGMENTIN 625 - ntuziaka maka ojiji, ọnụahịa, nyocha na analogues

Emeputa

Omume ọgwụ

Ime na lactation

Nsonaazụ

Mmekorita

Etu ị ga-esi, usoro nchịkwa na usoro onunu ogwu

Dodoụbiga ya ókè

Ntụziaka pụrụ iche

Etu esi eji ọgwụ Augmentin 625?

Weputara udi ya na ihe mebere ya

Mlọ ọgwụ

Ihe ngosi maka ojiji

Augmentin 625 - ọgwụgwọ dị mma maka ọrịa prostatitis

2 Ngwakọta na usoro onunu ogwu

6 Uzo esi ewere Augmentin 625

7 Ndụmọdụ pụrụ iche

Ihe ngosi maka ojiji

Ihe ngbanwe

Ọnọdụ nchekwa

IFlọ ọgwụ IFC

Pharlọ ọgwụ Pani

Pharmacodynamics na pharmacokinetics

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Analogs nke Augmentin

Augmentin maka ụmụaka

Mmanya ndakọrịta

Augmentin n'oge afọ ime na lactation

Nyocha banyere Augmentin

Ọnụahịa Augmentin

Nkọwa nke ụdị usoro onunu ogwu

Na-egosi Augmentin ®

Usoro onunu ogwu na nhazi

Mpempe mwepụta

Omume ọgwụ

Ihe ngosi maka ojiji

Ihe ngbanwe

Ọnọdụ nchekwa

IFlọ ọgwụ IFC

Pharlọ ọgwụ Pani

Mpempe mwepụta

Omume ọgwụ

Pharmacodynamics na pharmacokinetics

Ihe ngosi maka ojiji

Ihe ngbanwe

Nsonaazụ

Ntụziaka maka iji Augmentin: usoro nke ngwa, usoro onunu ogwu maka ndị ọrịa okenye na ụmụaka

Dodoụbiga ya ókè

Mmekorita

Usoro ahia

Ọnọdụ nchekwa

Exbọchị mmebi

Analogs nke Augmentin

Augmentin maka ụmụaka

Mmanya ndakọrịta

Augmentin n'oge afọ ime na lactation

Nyocha banyere Augmentin

Ọnụahịa Augmentin

Arụ Ọrụ:

Ndị na-ahụ maka ọgwụ

Nhazi ọkwa nosological (ICD-10)

Ihe onyonyo 3D

Nkọwa nke ụdị usoro onunu ogwu

Omume ọgwụ

Mlọ ọgwụ

Mlọ ọgwụ

Na-egosi Augmentin ®

Ihe ngbanwe

Ime na lactation

Nsonaazụ

Mmekorita

Usoro onunu ogwu na nhazi

Dodoụbiga ya ókè

Ntụziaka pụrụ iche

Mpempe mwepụta

Irationbọchị mmechi nke Augmentin

Ahapụ Gị Ikwu

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