Ọgwụ ndị na-abịa n'ọrịa shuga mellitus ọgwụ na ọgwụ maka ọrịa shuga 2

Mmetụta dị ala nke ọgwụ bụ iji mee ka mkpụrụ ndụ ndị na-eme ka mmadụ nwee ike imepụta insulin, meziwanye nnabata nke glucose site na uru ahụ, wee si ibelata ọkwa ya na ọbara. Ọ na - egbochi imepụta glucose n'imeju.

Ọgwụ na-eme ka metabolism dị ọcha, na -ewelata oke abụba na ọbara, na-ebelata ọbara ọgbụgba, na-egbochi mmepe nke nsogbu mamịrị (retinopathy, ọrịa obi).

Site na nhazi nke micronized, ọgwụ a ngwa ngwa ma bụrụ nke a na-ahụkarị n'ime afọ, nwere bioavailability zuru oke.

Ihe ngosiputa na usoro onunu ogwu

2dị nke abụọ nke ọrịa shuga mellitus na ọdịda nke antidiabetic nri na oke ibu.

Ọgwụ ka dọkịta depụtara ya. A na-ekpebi usoro onunu ogwu n’otu n’uche, na-eburu n’uchekwa ogo shuga n’elu afọ na-enweghị nri na awa 2 mgbe nri gasịrị.

Initialbọchị mbu nke 1.75 mg nke mannyl bụ mbadamba 0.5-1. Jiri nwayọ welite dose iji mee ka ọkwa shuga dịzie. Oke kachasị bụ mbadamba atọ kwa ụbọchị.

Iji nwekwuo usoro onunu ogwu, ha na-agaghari na 3.5 mg mannil na-amalite site na mbadamba 0.5-1 kwa ubochi.

Maninil 5 mg amalite na mbadamba 0,5 kwa ụbọchị. Mgbe egosiri, a na-eji nwayọ were ọgwụ 15 kwa ụbọchị rue 15 mg. Usoro ọgwụgwọ dị elu adịghị eme ka ọdalata shuga na-ebelata mannyl.

A na-ewere Maninil ọkara otu awa tupu nri. E jiri mmiri sachaa mbadamba ahụ na-ata ata. Usoro nke ihe karịrị mbadamba 2 kwa ụbọchị na-ekewa n'ụtụtụ na mgbede. Welie ọgwụ a n’okpuru nlekọta nke dọkịta.

Ọ bụrụ na ọgwụ kachasị ị ofụ ọgwụ adịghị arụ ọrụ, a na-edozi ajụjụ nke ịgbakwunye insulin na maninil.

Contraindications:

• ụdị shuga 1
• hypoglycemia,
• ọrịa shuga, ketoacidosis,
• decompensated pathologies nke akụrụ na umeji,
• ime, inye ụmụ ara,
• anabataghi ntinye nke sulfanilurea.
• Ga-ekwe omume mmeghachi omume:
• hypoglycemia,
• ọrịa dyspeptik
• mmeghachi omume nfụkasị ahụ

E kwesiri iji nlezianya dezie Maninil ka ndị ọrịa rịa afọ 60 (ihe ize ndụ nke hypoglycemia), yana ndị mmadụ ọrụ nlebara anya.

Etu ị ga - esi ghọta aha ọgwụ ọgwụ ndị dị n’okpo ọbara shuga

Ndị enyi m, ka m chetara unu na ọgwụ ọ bụla nwere aha mba ọzọ na-abụghị nke ya, a na-akpọ ya INN obere oge. E gosipụtara aha a n'akwụkwọ ndenye ọgwụ mgbe ọ kwụsịrị n'ụlọ ọgwụ. Aha ị na-ahụ na nkwakọ ngwaahịa n'ụlọ ahịa ọgwụ bụ aha azụmaahịa nke ụlọ ọrụ ọgwụ. A na-edekarị INN na nkwakọ ngwaahịa n'obere mbipụta aka nri n'okpuru aha azụmaahịa. Mgbe ụfọdụ, aha ndị a dakwasịrị.

Ya mere, Agaghị m ekwu maka otu nnọchite mgbanye shuga, dịka ọmụmaatụ, maninil, mana maka otu ọgwụ ọgwụ dabere na glibenclamide. N’ezie, a ga m enye ọmụmaatụ na analogues nke aha ahia yana obodo nke onye na - emepụta ọgwụ na - eme ka okpete daa.

Ọ ga-amasị m ikwu banyere otu ụdị ọgwụ shuga dị ala, mana tupu nke a, m kpebiri 'ịkpọsa ndepụta niile', ma kọwaa nkenke nke ọ bụla na ntinye ederede.

Maninil - ụdị mgbapụta

Manilin, foto nke egosiri na nkebi a, nwere ihe dị na ya bụ glibenclamide na filler:

• Methyl hydroxyethyl cellulose,
• Lactose Monohydrate,
• Iri ite
• Steeti magnesium,
• Ihe sịlịkọn dioxide
• Dye Ponceau 4R.

Ọ dị mfe ịchọpụta ngwaahịa nke ụlọ ọrụ German na-ahụ maka ọgwụ Berlin-Chemie (Menarini Group): mbadamba nkume nwere acha pinkish nwere chamfer na akara nkewa n'otu akụkụ. Dabere na usoro onodu ogwu, otu mbadamba ihe nwere ike ibu 3.5-5 mg nke isi ihe di n’ime ya.

Na netwọọ ahịa ọgwụ, enwere ike ịzụta ọgwụ na ndenye ọgwụ. Na Maninil, ọnụahịa ahụ bụ ezigbo mmefu ego - site na 140 ruo 185 rubles. Ọgwụ anaghị achọ ọnọdụ pụrụ iche maka nchekwa, mana ohere ụmụaka na ìhè anyanwụ ga-amachaghị. Ndụ nchekwa nke mbadamba nkume ahụ bụ afọ 3, ọgwụ agafewo n'okpuru.

Ohere nke ọgwụ ọgwụ

Ọrụ bụ isi nke glibenclamide bụ ịkwalite mkpụrụ ndụ β-sel nke agwaetiti nke Langerhans, na-ahụ maka mmepụta nke insulin. Βme ihe ana –eme sel bụ ka ọ dị n’usoro ọfụma na gburugburu ya. Mgbe ejichara, mbadamba nkume na-adigide ngwa ngwa mbadamba nkume ndị ahụ. Anaghị emetụta ọnụego nnabata nke ọdịnaya nke afọ na oge nri. Site na protein plasma, ọgwụ na-abanye na kọntaktị 98%. A na-ahụ elu nke ọkwa ya na ọbara ọbara mgbe elekere abụọ na ọkara gachara wee ruo ogo 100 ng / ml. Ọkara ọkara bụ ihe dịka awa 2, mgbe ewere kwa os - 7 awa. Dabere na onyonyo onyonyo nke oria, ndi n’eto mamria n’oge a nwere ike rue elekere 8 ma obu iri.

Ọgwụ ahụ bụ metabolized kachasị na imeju, na-agbanwe site n'enyemaka nke ndị na-abụghị pathocytes n'ime ụdị metabolites abụọ: 3-cis-hydroxy-glibenclamide na 4-trans-hydroxy-glibenclamide.

Ekwenyesiri ya ike na metabolites adịghị akpalite steeti hypoglycemic, na-ewepụ akụrụ na bile na-apụ n'ahụ ahụ kpamkpam n'ime ụbọchị 2-3.

Ọ bụrụ na mọ na - emebi emebi, a na - ejigide ọgwụ n’ ọbara n’ime ogologo oge. Site na ịmịpụta akịrị ya na mmamịrị, a na-ewepụ ya na oge, oge ọ ga-adabere n'ịdị ogo nke arụ arụ.

Karịa, na ụdị nwayọ nwayọ na-agafe agafe, ego anaghị edozi. Site na mwepụ nke creatinine ≤30 ml / min, ọnụego mkpochapụ metabolites na-ebelata, na-abawanye ọkwa nke ọgwụ n'ọbara. Ọnọdụ ndị yiri ya maka Maninil chọrọ titingation ma ọ bụ wepụ oge (ọ na-abụkarị n'ụdị ndị a ka etinyere insulin insal).

Ọnye na-bụ Maninil?

Emere ọgwụ a iji chịkwaa ụdị shuga 2 (ụdị na-abụghị insulin). Mpempe akwụkwọ ka enyere ndị ọrịa mamịrị mgbakwunye na enweghị mmetụta ebumnuche mgbe mgbanwe ndụ (obere nri carb, mmega ahụ zuru oke, mmezi nke oke ibu, ịchịkwa ọnọdụ mmetụta, nnabata ụra na izu ike).

Otu endocrinologist na-edepụta ọgwụ, na-agbakọ usoro ọgwụgwọ na-eburu n'uche nri, afọ onye ọrịa, ọkwa nke ọrịa ahụ, usoro ọnya na-emetụta ahụike, ịdị mma n'ozuzu ya na nzaghachi anụ ahụ na ọgwụ. A na-ekpebi usoro ọgwụgwọ dabere na profaịlụ glycemic nke onye ọrịa.

A na-enyekarị ọgwụ mmalite ka ọ dịkarịa ala - ọkara mbadamba ihe dị ka 5 mg ma ọ bụ 3.5 mg kwa ụbọchị. A na-elebara ndị ọrịa asthenic anya nke nwere hypocaloric anya pụrụ iche na mmezi onyonyo, na akụkọ mgbe enwere mwakpo hypoglycemic, yana ndị mmadụ na-arụ ọrụ ike. Izu izizi nke nchịkwa glycemic kwa ụbọchị chọrọ. A na-eme titing titition site na akaebe nke mita ahụ na n ’uche ndị dọkịta.

Usoro ọgwụgwọ Maninil bụ ihe dịka 15 mg / ụbọchị, nke bụ mbadamba 3 nke 5 mg ma ọ bụ mbadamba 5 nke 3.5 mg.

Mgbe Maninil dochie ọgwụ hypoglycemic ndị ọzọ, ọgwụ ịmalite na-eduzi ha. Mgbe akagbuola ọgwụ ndị gara aga, a na-akọwapụta ihe glucose nke ọma na nsonaazụ nyocha nke mmamịrị na ebumpụta ụwa, na-enweghị ekpughe ọgwụ. A na-enyocha mmeghachi omume nke anụ ahụ site na ntakịrị opekempe - mbadamba 0,5 nke 3.5 ma ọ bụ 5 mg. Irubere oke nri na ọnọdụ ndị ọzọ ndụ dị mma bụ iwu. Iji zere mmetụta ndị na-emetụta ya, a na-amụbawanye ọgwụ nke ọgwụ ọhụrụ nwayọ nwayọ. Onye ọrịa mamịrị ga-agwa ndị dibia bekee banyere mgbanwe niile gbasara ahụ ike.

Ndụmọdụ maka iji ya

Maninil na-atụ aro iji ya n'ụtụtụ, tupu nri ụtụtụ, ị glassụ iko mmiri dị ọcha. Mgbe ụkpụrụ gafere PC abụọ / ụbọchi, ana - ekewa ya ụzọ abụọ n’usoro ruru 2: 1. Iji nweta nsonaazụ ọgwụgwọ kachasị, ọ dị mma ị takeụ ọgwụ ahụ n'otu oge.

Nsonaazụ

Dabere na ntinye uche nke WHO, a na-atụle ugboro ole mmetụta ọjọọ nke mmetụta ọgwụ ọjọọ nwere n'ọtụtụ pụrụ iche:

• Ọtụtụ mgbe - site na 10%,
• Ọtụtụ mgbe - site na 1 ruo 10%,
• Mgbe ụfọdụ - site na 0.1 ruo 1%,
• N'oge na-adịghị anya - site na 0.01% ruo 0.1%,
• O siri ike na - rue 0.01% ma ọ bụ edeghị ọlị.

A na-agụ ndekọ ọnụ ọgụgụ nke ihe ojoo site na ị Manụ Maninil na tebụl.

A na-ahụkarị nsogbu nlegharị anya n'oge mmegharị ọgwụ ahụ ma pụọ ​​naanị nke onwe ya, na-enweghị nsogbu ọgwụ. Ọrịa dyspeptik n'ụdị ọgụ ọgbụgbọ, ọgbụgbọ, ọgbụgbọ anaghị achọ ọgwụ iji dochie anya ya.

Ọ bụrụ na enwere ụdị ọrịa hyperergic na glibenclamide, enwere ihe ize ndụ nke cholestasis intracranial nwere nsogbu na ụdị nnukwu nsị imeju.

Mmeghachi omume nfụkasị anụ ahụ na-agbanwegharịkarị, mana n'ọnọdụ ndị obere, ha nwere ike kpalite oke iyi egwu nke na-etinye ndụ nke ndị ọrịa shuga egwu.

Site na Maninil, enwere ike gosipụta ihe nfụkasị na mmetụta ndị ọzọ site na nro, ahụ ọkụ, ihe nrịbama nke ọrịa jaundice, nchọpụta nke protein na ule mmamịrị. N'ọnọdụ niile, ọ dị mkpa ịgakwuru dọkịta na-ahụ maka ịga ngwa ngwa.

N'ọnọdụ ụfọdụ, a na-edekọ mbelata ihe niile eji eme ọbara. Mgbe akagbuo ọgwụ, ọnọdụ ahụ agaghị agafe oge. Enwere ike ịgwọ onwe ya na ọgwụ ndị ọzọ na - akpasu hyperensitivity na onye ọrịa. Karịsịa, dai nke E124, nke a na-eji emepụta ọgwụ, bụ allergen dị ike.

Maninil - contraindications

Edeghị ọgwụ ahụ maka mmetọ nke ihe ndị dị na usoro ahụ. Ọzọkwa, egosighi ya:

• Maka ihe nfụkasị ahụ na diuretics na ọgwụ ọ bụla na-akpata sulfonylurea, nkwadebe sulfonylamide, probenecid,
• Ndị ọrịa mamịrị nwere ọrịa shuga 1, yana atrophy nke sel-,
• Ọ bụrụ na onye ahụ metụtara nwere metabolic acidosis, ọrịa mamịrị,
• Ndị nne dị ime na ndị na-enye nwa ara
• Ndị ọrịa nwere nnukwu akụrụ na akụrụ dysfunctions (ọkwa 3),
• Ndị acoụrụma na ndị na-a alcoholụbiga mmanya ókè (iyi egwu hypoglycemia).

Site n'ịxụbiga mmanya na-egbu egbu ume, ike hypoglycemic nwere nke glibenclamide na-abawanye, ọnọdụ nke ịxụbiga mmanya ókè na-ekpuchi ihe mgbaàmà nke ọdachi na-abịanụ.

Operationsrụ arụ ọrụ, mmerụ ahụ dị ukwuu, ịgba ọkụ buru ibu, ịnwe mbadamba ọgwụ ọ bụla. E jiri insulin dochie ha nwa oge, nke ga - enyere gị aka ịme ọfụma na plasma ngwa ngwa.

Enweghị mmachibido iwu zuru oke na njikwa nke njem na akụrụngwa ndị ọzọ dị mgbagwoju anya n'oge ọgwụgwọ Maninil. Ma ọgụ hypoglycemic nwere ike imebi nlebara anya na usoro iche echiche, karịsịa na njikọta ọgwụ na ọgwụ ndị na-ebelata shuga. Yabụ, ogo ihe ọ bụla na-arịa ọrịa mamịrị ga-enyocha onwe ya.

Nsonaazụ Njikọ Ọgwụ

Na usoro ọgwụgwọ na glibenclamide na clonidine, yana ckers-adrenergic blockers, reserpine, guanethidine, a na-egosipụta akara nke hypoglycemia na-abịanụ ma anaghị ekwe ka amata ọrịa shuga na-abịanụ.

La laụ ọgwụ n’oge niile na-akpalite ọgba aghara na - eme ka mita glucose ma na --ekwu ohere nke hypoglycemia.

Mee ka ohere nke glibenclamide ruo mwakpo hypoglycemic, ị nwere ike iji insulin mee ihe, insulin inhibitors, mbadamba shuga, ọgwụ ndị dabere na homonụ nwoke, ọgwụ steroid, antidepressants, β-blockers, clofibrate, ọgwụ ndị dabere na quinolone, coumarin, phenamine, disaminophen miconazole, PASK, pentoxifylline, perhexylin, pyrazolone, probenecid, salicylates, ọgwụ sulfonamidamide, ọgwụ mgbochi nke klas tetracycline, tritokvalin, cytost tics.

Ọ na-egbochi ọrụ nke ọgwụ ahụ, na-akpasu ọnọdụ hyperglycemic, ojiji nke acetazolamides, β-adrenergic igbochi ndị nnọchi anya, diazoxide, glucagon, barbiturates, diuretics, tubazide, glucocorticosteroids, ọgwụ phenothiazine klas, phenytoin, nicotinates, ọgwụ nje, ọgwụ nwoke gland thyroid.

Ọgwụ ọgwụ Coumarin, ranitidine, gastric H2 receptor antagonists, pentamidine, reserpine na-eme ihe a na-atụghị anya ya, na-eme ihe dị ka ndị na-enyocha ma ọ bụ na-egbochi ọrụ glibenclamide.

Nyere aka ịdoụbiga mmanya ókè

Dodoụbiga mmanya ókè nke glibenclamide (ma n'ụdị ya dị oke njọ ma na-akpasu iwe ahụ) na-enye hypoglycemia siri ike - na-enwe mmetụta ogologo oge, nnukwu ihe mgbaàmà na ndụ ihe atụ nke onye ahụ metụtara Ngosiputa amuma nke hypoglycemic ọgụ, oria obula gha aghaghi ima.

• Agụụ a na-achịkwaghị achịkwa
• Ogwe aka na ukwu,
• Tachycardia
• Anxietyba ụba nke ụjọ
• Icha acha na ọnya akpụkpọ ahụ.

Mgbe ụfọdụ enwere nsogbu adịghị adị nke nwa oge, paresthesia. Ọ bụrụ na enyeghị onye ahụ metụtara nlekọta ahụike mberede, ọ ga-adaba na prepoccomia precoma na coma, nke na-egbu egbu.

Nchoputa nke ihe ndi si na ha puta bu nzi ozi banyere onye aemebi site na ndi ikwu maara ogwu ndi oria ya na oria ya ndi ozo. A na-eme nnyocha ụlọ nyocha.

Nyocha nke ndị ahụ metụtara nye gị ohere inyocha ọnọdụ akpụkpọ ahụ (oyi, clammy, udu mmiri). Ọnọdụ okpomọkụ nwere ike ịdị nkịtị ma ọ bụ dị ala. Dabere n'ịdị njọ nke mwakpo ahụ, a na-ahụ ntụpọ akwara nke tonic ma ọ bụ ụdị clonic, mgbanwe na-enweghị ọkọlọtọ, na ihe ọdịdọ.

Ọ bụrụ na onye ahụ ka dị ndụ, ọ nwere ike sugarụọ shuga dị ụtọ ya na shuga mgbe niile, rie carbohydrates ọ bụla (swiiti, kuki) ọ bụla. Ọ bụrụ na ọnọdụ ahụ agbabeghị, ndị ọrịa mamịrị a n'ụlọ ọgwụ.
N'iji coma nọ n'ụlọ ọgwụ, a na-edozi ngwakọta glucose 40% (40 ml) iv. N'okpuru nlele nlele nke ụlọ nyocha, a na-agbanwe ọgwụ infusion site na enyemaka nke carbohydrates dị ala na-agbanwe agbanwe.

A mara ọkwa nke hypoglycemic ọgụ ogologo oge na nke na-egbu oge, na-akpasu iwe nke ike nke glibenclamide. Ọnọdụ ndị dị otú ahụ chọrọ ka a hụ onye e megburu n'ụlọ ọgwụ ruo ụbọchị 10 ma ọ bụ karịa site n'ilechi anya glycemia na usoro ọgwụgwọ ọrịa.

Ọ bụrụ na onye ahụ tara ahụhụ tookụrụ ọgwụ ugboro abụọ na mberede, ọ zuru iji mmiri sachaa afọ ahụ, nye onye ahụ ihe ọbụ andụ na otu iko tii ma ọ bụ ihe ọ juiceụ sweetụ dị ụtọ.

Analogues nke ọgwụ

Site na otu ihe mejupụtara Glibenclamide, Glibenclamide na Glibamide nwere ike dochie Maninyl. Ngosipụta, contraindications, mmetụta dị n'akụkụ bụ otu ihe. Dabere na koodu ATX nke ọkwa nke 4 maka Maninil, Glidiab, Glyclazide, Diabeton, Glurenorm, nke nwere mmetụta ọgwụgwọ yiri ya, nwere ike ịbụ analogues.

Ọzọ aro

Maka ndị ọrịa tozuru oke, ndị mmadụ nwere nri nwere obere kalori, asthenics, ndị ọrịa mamịrị nwere ọrịa imeju na akụrụ, ọnụego mbido nke Maninil belatara nke kacha nta n'ihi ihe egwu hypoglycemia. Ọ bụrụ na ndị ọrịa mamịrị agbanwela ibu, ndụ, a na-enyochakwa usoro ọgwụgwọ.

Ọ dị mkpa nlebara anya maka ndị ọrịa nwere ọrịa ụbụrụ, nsogbu ụbụrụ na ọnọdụ ndị ọzọ na-agbagha njikọta onye ọrịa na dọkịta. Nnyocha ụlọ nyocha nke ụdị ndị ọrịa kwesịrị ịmalite oge niile o kwere omume. Iji tulee njirimara niile nke nsonaazụ ọgwụ ahụ dị n'ahụ ahụ, edeburu ha iwu analogues na ịhapụ ngwa ngwa bekee.

Ọ bụrụ na ọrịa mamịrị anaghị etinye metformin, a na-enye ya ọgwụ glitazone dịka rosiglitazone ma ọ bụ pioglitazone. Site na ngosipụta ndị kwesịrị ekwesị, a na-agbakwunye mbadamba Maninil na ọgwụ antidiabet ọzọ na usoro ọrụ dị iche. Guarem ma ọ bụ Acarbose, nke, dị ka Maninil, na-akpali pancreas, anaghị ejikwa ya na usoro ọgwụgwọ siri ike.

Ogologo oge eji glibenclamide na-akụda mkpụrụ ndụ cells-sel, na-eduga ná necrosis, ma na-amalite inwe enweghị nchekasị na Maninil. Iji kwado pancreas, a na-ebufe ọrịa shuga na insulin (n'ozuzu ma ọ bụ na akụkụ, dabere na ogo atrophy ha).

Nyochaa ọgwụ nke ndị dọkịta na ndị ọrịa mamịrị

Banyere nyocha Maninil na-agwakọta. Ndị dọkịta mara ya dị ka ọgwụ ọgwụ hypoglycemic ọdịnala nwere nnukwu ihe akaebe siri ike nke ịdịmma na nchekwa. Ndi oria oria n’enweghi afọ ojuju n’inweta uru dị ukwuu na uru ndị ọzọ na-emetụta ya, mana inwale ike nke ọgwụ dịka nsonaazụ otu onye ọrịa siri dịkarịa ala.

Ndụmọdụ ndị dị na saịtị a bụ ụdị aha ntụgharị nke ntuziaka gọọmentị, ezubere maka ịkọwapụta ọhaneze, ọ bụghị maka ọgwụgwọ onwe. Nhọrọ nke ọgwụ na nkwadebe usoro ọgwụgwọ bụ nanị ọrụ dọkịta.

Nkọwapụta Maninil na ngosipụta maka ojiji

Maninil bụ ọgwụgwọ maka ụdị ọrịa shuga mellitus nke na-abụghị insulin. Ọ bụ mbadamba nkume pink maka nchịkwa ọnụ.

Ihe omume nke ogwu a sitere na mkpali nke imeputa insulin site na pancreas na mmụba na uche ya. N'ihi ya, ewepụtara insulin karịa ma na-eme ka ọ nwekwuo ike. Ọgwụ na - egbochi glycogenolysis (mmebi nke glycogen ka glucose) na gluconeogenesis (njikọ nke shuga site na ihe ndị na - adịghị ike na carbohydrate) na imeju. Nke a ga - enyere gị aka ịbelata ogo glucose ọbara.

Maninil na -ebelata ihe ize ndụ nke nsogbu nke ọrịa shuga 2 - mmebi nke usoro ụjọ ahụ, ọhụụ, obi, arịa ọbara.

Denye ọgwụ banyere mgbe oke ibu, nri na mmega ahụ eweghachila usoro metabolic na ahụ.

Maninil na-edozi shuga dị n'ọbara

Ekwesịrị ịnye ọgwụ ahụ site na endocrinologist. A na-ekpebi usoro onunu ogwu mgbe nyochachara ya na nyocha ọbara ọbara yana mmamịrị enwere ike idozi ya ka oge na-aga.

Mwepụta wepụtara ya na ihe mejupụtara

Ihe nọ n'ọrụ bụ microlized glibenclamide.

Otu mbadamba Maninil nwere site na 1.75 ruo 5 mg nke glibenclamide.

N'ihi ụdị ntọhapụ dị iche iche, ọ dị mfe ịhọrọ usoro kwesịrị ekwesị nke kachasị maka ọkwa ọ bụla maka ọrịa ahụ. Na ire ere i nwere ike ihu nkwakọ ngwaahịa a:

• 1.75 mg - 120 PC. (120 rub.),
• 3,5 mg - 120 pcs. (160 rub.),
• 5 mg - 120 pcs. (135 rub.)

Ndị na-esite na mmiri ndị a nọ na mbadamba ụrọ nke 1.75 mg na 3.5 mg:

• lactose monohydrate,
• nduku nduku
• methyl hydroxyethyl cellulose,
• colloidal silicon dioxide,
• stereta magnesium,
• ncha (E124).

Mpempe 5 mg nwere obere dị iche iche nke ndị ọpụpụ:

• lactose monohydrate,
• stereta magnesium,
• nduku nduku
• ncha (E124),
• ntụ ntụ talcum
• gelatin.

Ihe ngbanwe

Maninil na-contraindicated na ndị a:

• ụdị shuga 1
• uche banyere ihe ọ bụla mejupụtara
• nsogbu imeju na akụrụ,
• mgbochi afọ,
• hypoglycemic coma na precoma,
• afọ nke ịwa ahụ
• paresis nke afo
• ketoacidosis.

Agaghị eji ndị dị ime na ndị na-enye nwa ara na-eji ngwa ọrụ ahụ eme ihe. A na-egbochi Maninil maka ndị nwere mmanya na-egbu egbu.

Site na nhazi nke Maninil n’otu oge, mmanya nwere ike ibute nsonaazụ dị egwu n'ụdị hypoglycemia (shuga dị ala).

Effects nwere ike inwe mmetụta ọjọọ yana ị andụbiga mmanya ókè

Ọ bụrụ na ewere ya na ezighi ezi, Maninil nwere ike ibute ụdị hypoglycemia dị ukwuu, ọkachasị n'ụdị oke ị excessụ ọgwụ ahụ ma ọ bụ nke na-ezighi ezi, yana ị abuseụbiga mmanya ókè. Ihe ize ndụ ahụ na-abawanye site na mgbatị anụ ahụ na mberede, agụụ, metabolism na-agwụ ike (yana nsogbu endocrine).

N'oge mmalite ọgwụgwọ, imerụ anya ma ọ bụ ịmụba ka ọkụ na-enwu gbaa. Usoro a agbanwegharịrị ma ka oge na-aga ihe niile ga-alaghachi na mbụ.

A na-ahụkarị mmeghachi omume na-adịghị mma site na eriri afọ.

N’ọnọdụ ndị pụrụ iche, nsogbu bilitere n’ihe banyere ịmịnye ọbara (ihe ndị mejupụtara ọbara).

Iji belata ihe egwu dị na ya, a gharịrị ịgwọ ọrịa shuga na Maninil n'okpuru nlekọta nke ndị na - abịa endocrinologist.

Ogologo oge nke nchịkwa nke Maninil nwere ike ibu ọrụ maka mbelata ọrụ thyroid na mmụba nke ahụ mmadụ.

Ọ bụrụ n ’ị tooụ ọgwụ Maninil riri oke, ị nwere ike ịchọpụta ihu abụọ. Ejiri njiri mara agụụ, ụjọ, ahụ mmadụ, pallor nke anụ ahụ mara ya. N'emeghị ihe kwesiri ekwesi, nkụda mmụọ na nkụ nwere ike ibilite, nwụọ ọnwụ onye ọrịa. Ofzọ ime ihe n'ọnọdụ siri ike ka gị na dọkịta kwurịta tupu oge eruo.

Attentionaa ntị! Do overụbiga ọgwụ ókè bụ ihe dị ize ndụ. Meputa ubochi ubochi kwesiri ibu onye okacha amara na nyocha nke nyocha. Anabataghị ọgwụ banyere onwe gị.

Iwu nnabata

N'adịghị ka ụfọdụ ọgwụ hypoglycemic, Maninil ga-ewere n'ụtụtụ n'ụtụtụ afọ. Jiri iko mmiri sachaa mbadamba mbadamba. Ọ bụrụ na dọkịnta ahụ tụrụ aro ikewapụta ogwu ahụ ka a gwọọ ya abụọ, mgbe nke abụọ a ga-eme mgbede a, kamakwa tupu nri.

Dị Mkpa! Iji nweta nsonaazụ kachasị mma, ị ga-a drinkụ ọgwụ ahụ n'otu oge kwa ụbọchị. Ọ bụ ihe anakwereghị ịhapụ aghụghọ.

N'ihi n'ụdị mgbapụta dị iche, na ọgwụ ọgbara ọhụrụ enwere ihe dị ka atụmatụ iri abụọ maka iji Maninil. Ọgwụ endocrinologist kpebiri na oge ọgwụgwọ ọgwụ dabere n'ọnọdụ onye ọrịa. N'oge ọgwụgwọ, ekwesịrị ileba anya kwa izu maka ọkwa glucose dị n'ọbara na mmamịrị.

Attentionaa ntị! Ọ bụrụ na nri ma ọ bụ ọkwa nke mmega ahụ agbanweela, ị ga-agwa dọkịta gị. Nke a nwere ike ịbụ ihe kpatara ịhazigharị usoro ọgwụ a.

Enwere ike iji maninil mee ihe na hypoglycemic ndị ọzọ (insulin, metformin), ọgwụ anabolic, ACE inhibitors, homonụ nwoke. Site na nhazi oge a na ọgwụ ndị ọzọ, mmetụta Maninil nwere ike ịbawanye ma ọ bụ belata. Ekwesiri ichebara nke a echiche mgbe ị na-ekpebi usoro onyonyo.

Maka usoro ọgwụgwọ na-enweghị isi na Maninil ma ọ bụ anabataghị akụrụngwa ya maka ịgwọ ụdị ọrịa shuga 2, enwere ike ịhọrọ ọgwụ ọzọ. Enwere nhazi (site na ihe na-arụ ọrụ) yana ihe nhazi (site na ọgwụgwọ) analogues nke Maninil. Ka anyị tụlee ụfọdụ n’ime ha.

Kedu otu m ga - esi dochie Maninil - tebụl

Nyocha nyocha Ndidi

Edere ọgwụ a maka ndị ọrịa nwere ọrịa shuga nke 2. Ọ bụ dọkịta ka o nyere nne nne anyị. Anyị na-enweta ya na ahịa ọgwụ maka nri preferential. Ọnụ ego ọgwụ a bụ 164 rubles. Ekwesịrị iji nlezianya mee ya, dịka otu dọkịta si eduzi ya. N'oge nnabata, ọ dị mkpa ịchịkwa ọkwa nke glucose dị n'ọbara. Nri n'oge, ma oburu na hypoglycemia nwere ike itolite. Nne nne anyi ewere ogwu ndia n’ime onwa abuo ugbua. Obi na-adị ya ụtọ, ọ na-ebi ndụ zuru oke. Ọgwụ dị irè, na-anagide ọrụ ya n'ụzọ zuru oke.

vbtkjvf333

http://otzovik.com/review_3231064.html

Girlsmụ nwanyị, mụ onwe m so gị - enwere m ọrịa shuga: belata ibu - shuga na-abịaru ọsọ, gbakwunye ya - ọ na-agbakọta. Akọnuche m na-ekpuchi obere anya m mgbe anyị atọ (mụ na ya, ya na ndị ọrịa shuga) malitere iri nri. Lee, anyị na-agbaji. Ugbu a, m dọtara onwe m ọzọ - ma tụfuo ntakịrị. Ana m ewere Maninil 3.5 - 1 mbadamba tupu nri na Glucofage 500 na njedebe nke nri n'ụtụtụ na mgbede. Enwere m mmetụta nke ọnọdụ m n'ụzọ zuru oke: ọbụlagodi m nwere ike ikpebi shuga m nke ọma.

veresk

http://age60.ru/PRINT-f3-t373.html

Enwere m mmasị na Maninil, agụụ na-enweghị atụ na mmeghachi omume dị oke egwu, mana, dịka ha na-ekwu, onye ọ bụla nwere nke ya.

Androlik500

Iji mee ka ọgwụgwọ ọrịa shuga dị irè, ị ga-agbasochi ndụmọdụ ndị a anya. Usoro ọgwụgwọ nke maninil na-ekpebi ya site na nsonaazụ nke ọmụmụ. Mgbe ị na-a therapyụ ọgwụ, ọ dị mkpa iji nyocha glucose oge niile zere ị fromụ mmanya.

More banyere ọrịa shuga:

N'ụtụtụ na n'ehihie mgbe m risịrị nri, m na-ewere otu mbadamba mbadamba maninil 3,5 m / g, i.e. 10.5 m / g kwa ụbọchị. Ana m eri ihe niile, i.e. Ana m erikwa atọ ụtọ. Ana m achọpụta shuga dị m n'ụtụtụ maka afọ efu. Site na nri na ụdị ọgwụgwọ a, ọkwa shuga dị n'ọbara anaghị agafe 6.5 m / mol. Achọpụtaghị ihe ịrịba ama nke ọrịa shuga - oke ibu, itching, urination ugboro ugboro, adịghị ike, akpịrị ịkpọ nkụ. O guzobere iwu a n'onwe ya. A maara m na iwu ahụ ezighi ezi ma enwere ike iwere manila nke ukwuu. Gwa m ka esi eme ya.

Nkewa (ndepụta) nke ọgwụ na - belata shuga maka ụdị shuga 2

Ebe ọ bụ na enwere ọtụtụ ọgwụ iji belata shuga ọbara, ekpebiri m ịme ka ị mata ha. Nwee onye ọ bụla dị n'isiokwu a. Maka ịdị mma gị, m ga-egosi na brackets aha azụmahịa kachasị ewu ewu, mana cheta na enwere ọtụtụ ndị ọzọ. Yabụ lee, ha bụ:

1. Otu biguanide na onye nnọchi anya ya bu metformin (siofor).
2. Otu sulfonylurea na ndị nnọchi anya ya bụ glibenclamide (maninyl), glyclazide (diabeton mv 30 na 60 mg), glimepiride (amaryl), glycidone (glurenorm), glipizide (minidiab).
3. Ndị otu na-ahụ maka ụrọ na naanị nnọchite anya ya bụ reaglinide (novonorm).
4. Otu thiazolidinedione na ndị nnọchi anya ya bụ rosiglitazone (avandium) na pioglitazone (actos).
5. Otu nke alfa-glucosidase inhibitors na onye nnọchi anya ya bu acarbose (glucobai).
6. Otu nke dipeptidyl peptidase-4 inhibitors (DPP-4) na ndi nnochite anya ya bu vildagliptin (galvus), sitagliptin (Januvia), saxagliptin (onglise).
7. Otu nke agonist glucone-like peptide-1 (GLP-1) na ndi nnọchi anya ya bu exenatide (byeta), liraglutide (victose).
8. Ọhụụ Otu nke inhibitors nke sodium-glucose-cotransporter ụdị 2 inhibitors (SGLT2 inhibitors) - dapagliflozin (Forsig), canagliflozin (Invokana), empagliflosin (Jardians)

Ọgwụ ndị na-ebelata ọbara n'ọbara Biguanide

Otu biguanide guzogidesiri ike na ọgwụ nile nke na - eme ka a ghara ịmịnye mmadụ ọrịa shuga 2dị nke Abụọ.

Naanị onye nnọchi anya bụ metformin. Ogwu sitere na otu a nwere nsogbu nsogbu, na-ebelata insulin iguzogide. Mana, dị ka ọ tụgharịrị, ha nwere ọtụtụ mmetụta ndị ọzọ dị mma, dịka ọmụmaatụ, a na-eji ya belata ma belata.

N’edemede ya "Metformin - ntuziaka maka ojiji" Ọ bụghị naanị na akọwapụtara m ọgwụ dị ukwuu iji belata ọkwa nke glucose na ọbara nke ndị ọrịa mamịrị, kamakwa, edepụtara aha aha ahia na analogues.

Na ederede "Metformin maka oke ibu: uru niile na ọghọm" Edere m banyere iji ọgwụ eme ihe maka ebumnuche na-enweghị oke.

Ọgwụ shuga dị n’ọbara sitere na kọlụm sulfonylurea

Ọgwụ shuga dị n’ọbara sitere na kọlụm sulfonylurea. Nke a bụ nnukwu nnukwu otu, ndị na-echepụtakwa ogologo oge gara aga. na nhazi ha ha nwere ọgwụ mgbe ochie nke sitere na glibenclamide (maninyl), nke ọgbọ ọhụụ, dịka glimepiride (amaryl).

Mbadamba shuga dị ala nke dabeere na sulfanylurea nwere mmetụta na-akpali akpali na pancreas ma ọ bụghị mgbe niile dabara ndị ọrịa mamịrị ụdị nke abụọ.

Ugbu a enwere naanị otu edemede “Ọrịa shuga mv 30 na 60 mg n'ịgwọ ọrịa shuga”, mana n’oge na-adịghị anya, a ga-enwe mbipụta na ndị nnọchi anya ndị ọzọ, yabụ ana m akwado ka ị denye aha na isiokwu ọhụrụ ka ịghara ịgbaghara mbipụta ahụ.

Alfa glucosidase inhibitors - mbadamba nwere nnukwu shuga

Onye nnọchi anya sitere na otu alfa-glucosidase inhibitors - enzyme nke eriri afọ - na-egbochi nnabata nke carbohydrates ma si otú ahụ belata shuga ọbara dị elu.

Nanị onye nnọchi anya bụ acarbose (Glucobay). Ọ bụghị onye isi ihe nrịba ama maka ọrịa shuga 2, kama ọ bụ nke inyeaka, maka na ọ nweghị mmetụta na-ebelata shuga.

A na - ejikọkarị Acarbose na ọgwụ ndị ọzọ. Gụọ gbasara ọgwụ a na-ebelata shuga dị n’ọbara “Acarbose na ihe niile gbasara ya.”

Nke ahụ bụ ihe m chọrọ ịgwa gị taa. N'ime edemede m ọzọ, m ga-aga n'ihu na akụkọ banyere ọgwụ ndị na - eme ka okpukpo belata nke ìgwè sulfonylurea na otu ndị ọzọ. Ọ bụrụ na ị nwere ajụjụ ma ọ bụ mgbakwunye, biko kwuo okwu na nkwupụta. A na m asịkwa gị nke ọma. Ka ọ dị!