Etu esi eji ọgwụ Glyclazide mee ihe? > Ọgwụgwọ na mgbochi

Sdị usoro onunu ogwu - mbadamba nkume: cylindrical dị larịị, ọ fọrọ nke nta ka ọ bụrụ ọcha ma ọ bụ na-acha ọcha, nwere ihe egwu na bevel (10 ọ bụla na ngwugwu ọnya, na ngwugwu kaadi 3 ma ọ bụ 6 na ntuziaka maka iji Gliclazide).

Ngwakọta 1 mbadamba:

ihe na-arụ ọrụ: gliclazide - 80 mg,
ihe inyeaka: stachi 1500 (ọka bred pregelatinized ọka breeki), sodium lauryl sulfate, lactose monohydrate, magnesium stearate, ssumum croscarmellose.

Mlọ ọgwụ

Glyclazide - usoro nke sulfonylurea nke ọgbọ nke abụọ, onye na-ahụ maka hypoglycemic.

Usoro nke ị theụ ọgwụ ahụ si bụrụ n'ihi ikike nke ịkpali nnabata nke insulin na-a pancụ, mee ka insulin-secretory nwee mmetụta glucose, ma mee ka mmetụta nke anụ ahụ ka insulin. Gliclazide na-akpali ọrụ nke enzymes intracellular dị ka akwara glycogen synthetase. Na-ebelata oge dị n'etiti oge iri nri rue mmalite insulin insulin. N'adịghị ka ihe ndị ọzọ na-emepụta sulfonylurea, ọ na-eweghachite ọnụ ọgụgụ kachasị elu nke mmiri insulin. Na-ebelata hypglycemia postprandial.

Gliclazide dị irè na metabolism na latent diabetes mellitus, gụnyere ndị ọrịa nwere oke ibu usoro iwu. A na-ahụta nkọwa nke profaịlụ glycemic ụbọchị ole na ole mgbe ịmalite ọgwụgwọ. Ọgwụ na-egbochi mmepe nke microvasculitis, gụnyere mmebi nke retina nke anya. Na-egbochi nchịkọta platelet. Na-abawanye fibrinolytic na heparin, yana nnagide heparin. N'ụzọ dị mkpa na-abawanye usoro nrụpụta nke otu ihe si dị. Ọ na-egosipụta ọrụ antioxidant, na-emezi vascularization.

Site na nephropathy mamịrị, a na-ebelata proteinuria. Site na iji ogologo oge, ọ na-enyere aka belata proteinuria na ndị ọrịa nwere ọrịa nephropathy.

Ebe ọgwụ ahụ nwere mmetụta kachasị ukwuu na mbido insulin insulin ma ghara akpata hyperinsulinemia, ọ dịghị ebute mmụba nke ahụ. Ọzọkwa, n’ime ndị ọrịa buru ibu, gliclazide na-eme ka mmadụ felata, na-eri nri kalori dị ala.

O nwere ọrụ antiatherogenic, na-ebelata ịta cholesterol n'ime ọbara.

Ngwakọta antioxidant na hemovascular nke gliclazide na-enyere aka belata ihe ize ndụ nke ịmalite nsogbu vaskụla na ndị ọrịa nwere ọrịa mellitus.

Mlọ ọgwụ

Ihe eji amata Gliclazide bu ihe ndi ozo. Mgbe onral ogwu nke 40 mg, ntinye uche kachasị (C_maxA mara ihe dị ka awa 2-3 ma ọ dị 2-3 μg / ml, mgbe ị aụsịrị ọgwụ nke 80 mg, akara ndị a bụ awa 4 na 2.2-8 μg / ml, n'otu n'otu.

Njikọ ya na protein protein bụ 85-70%, olu nkesa bụ 0.35 l / n'arọ. Ekwesara itinye uche ị nweta ihe n'ime ụbọchị 2.

Gliclazide bụ metabolized na imeju na nguzobe nke metabolites asatọ. Ọnụ ọgụgụ nke metabolite bụ isi bụ 2-3% nke ngụkọta ngụkọta were, ọ nweghị nke hypoglycemic, mana ọ na - emetụta microcirculation.

Nkera-ndu (T_½) - awa 8-12. Ọgwụ ahụ bụ naanị akụrụ: 70% - n'ụdị metabolites, ọ bụghị ihe karịrị 1% - agbanweghi. Ihe dịka 12% nke gliclazide bụ eriri afọ na-ekpu ka metabolites.

Nleta ọgwụ Pharmacokinetic n'ọnọdụ ụfọdụ:

ọrụ akụrụ na imeju: a bụrụ na ọrịa ịba ọcha n'anya na nnukwu ọdịda akụrụngwa, mgbanwe na ọgwụ ọgwụ nke gliclazide ga-ekwe omume, akụkụ nke hypoglycemia na ndị ọrịa dị otú ahụ nwere ike ịdị ogologo, nke chọrọ usoro zuru oke,
ịka nká: enweghị ntụpọ ọgwụ achọpụtara.

Ihe ngbanwe

ụdị ọrịa shuga mellitus 1 (gụnyere ụdị Ọdịmma nke ụmụaka),
ọrịa shuga na hyporosmolar
ọrịa mamịrị ketoacidosis,
hyporthyroidism,
nnukwu akụrụ na / ma ọ bụ imeju akwara,
mmerụ ahụ dị ukwuu na ọkụ,
ụyọkọ galactose, ụkọ lactase, glucose-galactose malabsorption,
afọ ruo afọ 18
ime na lactation
ojiji nke miconazole,
hypersensitivity na mpaghara ọ bụla nke ọgwụ, sulfonamides ma ọ bụ ọgwụ ndị ọzọ nke ìgwè sulfonylurea.

A naghị atụ aro iji Gliclazide na njikọ na Danazol, phenylbutazone, ethanol.

Gliclazide, ntuziaka maka ojiji: usoro na usoro onunu ogwu

Ekwesịrị iji ọnụ were glyclazide mbadamba ndị Glyclazide.

Na mmalite ọgwụgwọ, a na-enyekarị 80 mg (1 mbadamba) oge 1 kwa ụbọchị. N'ọdịnihu, dọkịta na-ahọrọ usoro mmezi ya n'otu n'otu, ọ nwere ike ịbụ 80-320 mg kwa ụbọchị. Otu ọgwụ ekwesịghị ịgabiga 160 mg. Mgbe ị na-edepụta ọgwụ ndị dị elu, ị ga-a theụ ọgwụ ahụ ugboro abụọ n'ụbọchị n'ụbọchị isi nri.

Usoro akwadoro ịmalite maka ndị ọrịa agadi (karịa afọ 65) bụ 40 mg (½ mbadamba) otu ugboro n'ụbọchị. Ọ bụrụ na ọ dị mkpa, inwetakwu ọgwụ ị nwere ike ịba ụba. Shouldbawanye usoro onunu ogwu kwesiri ime n’etiti opekata mpe ubochi 14 n’okpuru akara glucose obara.

N'ihe dịkarịa ala kwa ụbọchị (40-80 mg), a na-atụ aro Gliclazide maka ndị ọrịa nwere akụrụ / ọrịa ịba ọcha n'anya, na ndị ọrịa nwere nsogbu ibute ọrịa hypoglycemia: ọrịa siri ike ma ọ bụ na-adịghị akwụ ụgwọ endocrine ọrịa (gụnyere hypothyroidism, adrenal na pituitary insufficiency), ọnya ọnya siri ike (gụnyere ọrịa obi obi siri ike, atherosclerosis dị elu, atherosclerosis siri ike nke akwara carotid), enweghị nsogbu ma ọ bụ erighị ihe na-edozi ahụ. Nwepu nke glucocorticosteroids mgbe ochichi ogologo oge ha na / ma ọ bụ nchịkwa na usoro ọgwụgwọ dị elu.

Mgbe ị na-ebufe onye ọrịa na Glyclazide site na onye ọzọ na-ekwu okwu hypoglycemic, a gaghị achọ oge ntụgharị. N'ihe banyere iji dochie nkwadebe sulfonylurea ọzọ na ndụ ogologo (dịka ọmụmaatụ, chlorpropamide) site na gliclazide, a ga-enwerịrị ileba anya na ọnọdụ onye ọrịa ịzere mmepe nke mmetụta mmụba na hypoglycemia.

Ọ bụrụ na ọ dị mkpa, enwere ike ịkelata Gliclazide yana insulin, alfa-glucosidase inhibitors na biguanides.

Enwere ike ịnye insulin ndị ọrịa nke na-ewere Glyclazide n'ụzọ zuru oke ịchịkwa ọkwa glucose dị n'ọbara. Ekwesịrị ịgwọ ọrịa n'okpuru nlezianya nke dọkịta.

Y’oburu n’ibu ogwu ozo, amachibidoro ya okpukpu abuo n’echi ya.

Dabere na mmeghachi omume metabolic nke onye ahụ (glucose ọbara, hemoglobin glycated) nke onye ọrịa, enwere ike idozi ọnụọgụ ọgwụ ahụ n'oge ọgwụgwọ.

Nsonaazụ

site na usoro nri: afọ mgbu, afọ ọsịsa / afọ ntachi, ọgbụgbọ, ọgbụgbọ (ogo nke mgbaàmà ndị a na-ebelata ma ọ bụrụ na ị were ọgwụ ahụ).
na akụkụ nke imeju na biliary tract: ubara ọrụ nke enzymes imeju, cholestatic jaundice, ịba ọcha n'anya,
site na akwara hemopoietic: leukopenia, thrombocytopenia, anaemia, granulocytopenia,
sitere na akwara obi: epistaxis, hypotension arterial, ọrịa ụbụrụ, akwara, palpitations, obi ike, tachycardia, infarction myocardial, ụkwụ ọria, thrombophlebitis,
n'akụkụ akụkụ ahụ nke ọhụụ: nkwarụ anya nke na-adịte aka (na-abụkarị mmalite nke ọgwụgwọ),
Mmeghachi omume nfụkasị: itching, erythema, friji anụ ahụ (gụnyere mmekpa ahụ na mmeghachi omume malulopapular), urticaria, vasculitis nfụkasị, angioedema.

Ihe mgbaàmà nke hypoglycemia: iro ụra, ike ọgwụgwụ, isi ọwụwa, nkụchi, adịghị ike, ọsụsọ, ụjọ ahụ, paresthesia, ịma jijiji, ịma jijiji, ọgbụgbọ, ọgbụgbọ. Ihe ngosi ndi a bu kwa ekwe omume: agu, nkpagbu uche, ihe itu ura ura, ogba aghara, mkpasu iwe, ikwu okwu na nkpagbu, belata mmeghari ahuhu, ogba aghara, obi mmadu, nkpagbu, ahuhu, aphasia, nkpagbu, njide onwe onye, imamiri ihe, bradycardia, iku ume ugboro ugboro. , obi nkoropụ, ọnwụ nke mmụọ. Hypoglycemia nwere ike ibute coma na ọnwụ. Patientsfọdụ ndị ọrịa na-egosi ihe ịrịba ama nke usoro nchịkwa mgbochi adrenergic: sweating, skin clammy, palpitations, nchegbu, ọbara mgbali elu, angina pectoris, tachycardia, cardhyac arrhythmia - mgbaàmà ndị a na-apụkarị mgbe ha gachara carbohydrates.

Dodoụbiga ya ókè

Ọ bụrụ na ịdoụbiga mmanya ókè, hypoglycemia na-amalitekarị.

Maka mgbaàmà na-agafeghị oke, ịkwesịrị ịbawanye ụba nke carbohydrates na nri, belata dose nke Gliclazide na / ma ọ bụ mezie nri ahụ. Ruo mgbe ọnọdụ ahụ kwụsịrị kpam kpam, onye ọrịa ahụ kwesịrị ịnọ n'okpuru nlekọta ahụike.

Ọnọdụ hypoglycemic siri ike nwere ike ịdabere na nkwarụ, coma na nkwarụ akwara ndị ọzọ. Ndị ọrịa dị otú a chọrọ nlekọta ahụike mberede, ọ dị mkpa ịnweta ụlọ ọgwụ ozugbo.

Ọ bụrụ na enyo enyo na hypoglycemic coma na-enyo enyo ma ọ bụ guzosie ike, ọgwụ ọgbụgba nke 50 ml nke 20-30% nke dextrose (glucose) na-egosi. Na-esote, mkpochapu okpukpu 10% dextrose dị mkpa iji mee ka ọkwa glucose ọbara dị karịa 1 g / l. Ọ dịkarịa ala, ụbọchị abụọ chọrọ iji nlezianya nyochaa. Ekwesịrị ijikọ ọgwụgwọ yana idobe na ịnọgide na-arụ ọrụ dị mkpa nke ahụ.

Nchọpụta adịghị arụ ọrụ n'ihi na gliclazide na - egbochi protein protein.

Ntụziaka pụrụ iche

Iji zere ihe ize ndụ nke ịmalite ọdịdọ hypoglycemic, dọkịta kwesịrị iji nlezianya họrọ nke Glyclazide, nye onye ọrịa ndụmọdụ doro anya maka ị theụ ọgwụ ahụ, ma nyochaa nnabata na ntuziaka ndị a.

Gliclazide ka enwere ike inye ndị ọrịa ahụ ike inye ha nri oge niile, tinyere nri ụtụtụ. Ihe dị mkpa iri nri carbohydrate bụ n'ihi oke ihe ịba ụba nke hypoglycemia bụrụ na enwere nri na-egbu oge, ego ezughi ezu ma ọ bụ ọdịnaya carbohydrate dị ala. Ihe ize ndụ nke hypoglycemia na-abawanye site na nri nwere obere kalori, ị alcoholụ mmanya, usoro nchịkwa nke ọtụtụ ọgwụ site na otu ụdị sulfonylurea, yana mgbe ọ gbasịrị ogologo oge ma ọ bụ mgbatị ahụ ike. Hypoglycemia nwere ike ibute ogologo ma sie ike, nke chọrọ ụlọ ọgwụ onye ọrịa na iwebata glucose ruo ọtụtụ ụbọchị.

Nnukwu hypoglycemia ga-ekwe omume ka ị na-a anyụ ọgwụ ọonyụ sulfụ sulfonylurea ọ bụla. Ndị ọrịa nwere nsogbu, ndị agadi, ndị ọrịa na-enweghị isi (ma ndị isi na nke abụọ) nwere mmerụ ahụ.

Ọ dị ndị ọrịa na ndị ezinụlọ ha mkpa ịkọwa ihe egwu nke ọnọdụ hypoglycemic, kwuo maka mgbaàmà ha na ụzọ ọgwụgwọ, ma kọwaa ihe ndị na-akpata mmepe nke nsogbu a. Onye ọrịa ahụ kwesịrị ịghọta nke ọma na iri nri, mmega ahụ oge niile na ilele oge nke ọkwa glucose ọbara. A ga-adọ ndị ọrịa na-arịa ọrịa shuga ume ịba ụba maka ọrịa hypoglycemia n'ihe banyere agụụ, ịveraụ ihe ọholicụ alcoụ na-egbu egbu na ọgwụ mgbochi mkpali.

Ọrịa hypoglycemia na-apụ n'anya mgbe eri nri nwere carbohydrate, dị ka shuga. Ọtọ anaghị atọ ụtọ. N'agbanyeghị nnwere onwe izizi mbụ, hypoglycemia nwere ike ịmaliteghachi. Ọ bụrụ na achọpụtara ihe mgbaàmà siri ike ma ọ bụ ruo ogologo oge, ọbụlagodi mmelite nwa oge na ị carbohydụ carbohydrate, a chọrọ nlekọta ahụike, gụnyere ụlọ ọgwụ.

Ofdịmma nke nchịkwa glucose ọbara n’oge ọgwụgwọ antidiediiki nwere ike ibelata n’okpuru ihe ndị a: ahụ ọkụ, ọrịa na-enweghị isi, ịwa ahụ, trauma, ọnọdụ nrụgide. N'ọnọdụ ụfọdụ, enwere ike ịchọ iwebata insulin.

Irè nke mbadamba Gliclazide, dị ka ọgwụ ọ bụla ọzọ nke hypoglycemic ọgwụ, na-ebelata ka oge na-aga. Ihe kpatara ọnọdụ a nwere ike ịbụ mbido ọrịa shuga ma ọ bụ mmeghachi omume na-adịghị ike maka ọgwụ. A na - akpọ ihe omume a na - anọghị nso na nsonaazụ nke ọgwụgwọ, na - emetụta enweghị isi mmetụta na mbido ọgwụ. Nkwubi okwu banyere enweghi mmetụta nke abụọ ka enwere ike ịmezi mgbe ejiri nlezianya wee dozie ya na ileba anya na ntinye uche na ndị ọrịa.

N'ime ndị ọrịa nwere ụkọ glucose-6-phosphate dihydrogenase, ọgwụ sitere na otu sulfonylurea, gụnyere glycazide, nwere ike ibute mmepe nke anaemia hemolytic. N'akụkụ a, a na-atụ aro ịtụle ohere nke usoro ọgwụgwọ ọzọ site na iji ọgwụ ọzọ na klas ọzọ ma ọ bụ jiri Glyclazide tinye nlezianya dị ukwuu.

N'oge a na-eji Gliclazide, ọ dị mkpa iji nyochaa oge ọrụ nke akụrụ, imeju, usoro akụrụngwa, yana ọnọdụ ophthalmic. Mgbe ị na-atụle ọkwa glucose ọbara, ọ na-atụ aro iji tụọ ọdịnaya nke hemoglobin glycated (ma ọ bụ glucose na plasma ọbara venous na-ebu ọnụ). Na mgbakwunye, inyocha onwe nke glucose nwere ike ịba uru maka ndị ọrịa.

Mmetụta ikike ịkwọ ụgbọala na usoro dị mgbagwoju anya

Gliclazide anaghị emetụta ma ọ bụ nwee obere mmetụta na ọrụ psychophysical nke mmadụ. Agbanyeghị, n'oge ọgwụgwọ, ọkachasị na mmalite ọgwụgwọ, ndị ọkwọ ụgbọ ala na ndị mmadụ na-arụ ọrụ na ụlọ ọrụ nwere ike ịdị ize ndụ kwesịrị ịkpachara anya maka ọrịa hypoglycemia.

Ime na lactation

Enweela data ole na ole banyere ụlọ ọgwụ gbasara ojiji gliclazide n'oge ime. Enwere ihe omuma banyere ihe eji eme ihe ndi ozo.

Na nyocha ụmụ anụmanụ, ọnụnọ nke mmụba ọmụmụ banyere oke doses nke gliclazide.

Dika ihe eji akpachapụ anya, a naghị akwado ọgwụ ahụ maka ụmụ nwanyị dị ime. Agbanyeghị, iji zere ibute ọrịa ụmụaka na-arịa ọrịa ụmụaka, a chọrọ iji nlezianya nyochaa ọrịa shuga na nne. Ejighị ndị na-ahụ maka ọgwụ mgbochi na ụmụ nwanyị dị ime, insulin bụ ọgwụ ịhọrọ. Mgbe ị na-eme atụmatụ ịtụrụ ime ma ọ bụrụ na ime dị n’oge ị na-a gụ gliclazide, a na-atụ aro ka iji ọgwụ insulin dochie ọgwụ ọnụ.

Amabeghị ma ọgwụ ahụ abanye na mmiri ara nne, na njikọta nke a, a na-egbochi Glyclazide n'oge a na-enye ya ara.

Mkparịta ụka ọgwụ ọjọọ

Ekwekọrịta miconazole concoitant (n'ụdị usoro onunu ogwu ma ọ bụ n'ụdị nke gel maka ngwa na mucous membranes nke onu), ebe ọ na - ebulite mmetụta nke gliclazide ma, n'ihi nke a, na - ebulite ohere nke hypoglycemia dị ukwuu, ruo coma.

Nchikota a choroghi:

phenylbutazone (na usoro onunu ogwu maka iji aru aru): a na - ebuli mmetụta hypoglycemic nke sulfonylureas ike. A na-atụ aro ọgwụ mgbochi mkpali ọzọ. Ọ bụrụ na ebumnuche nke njikọta dị otú a ziri ezi, a kwesiri ilebara ọkwa glucose ọbara anya nke ọma, ma ọ bụrụ na ọ dị mkpa, dozie dose nke glycoslazide (ma n'oge ọgwụgwọ njikọta na mgbe ọpụpụ phenylbutazone),
ethanol: na - akwalite hypoglycemia nke ukwuu ma nwee ike bute mmiri hypoglycemic.Oge ị therapyụ ọgwụ, ịkwesịrị ịhapụ ị beụ ihe ọholicụholicụ na-aba n'anya na ị andụ ọgwụ ethanol nwere,
danazol: nwere ọrịa mamịrị; anaghị akwado nchịkwa ya n'oge ọgwụgwọ hypoglycemic. Agbanyeghị, ọ bụrụ na nchịkwa dị mkpa, a kwesịrị idozigharị ọgwụ nke Gliclazide.

Ngwakọta chọrọ ịkpachara anya:

ndị ọrụ hypoglycemic ndị ọzọ (insulin, acarbose, biguanides), beta-blockers, angiotensin-na-agbanwe enzyme inhibitors (enalapril, captopril), fluconazole, histamine H blockers₂-receptors, sulfonamides, ọgwụ mgbochi mkpali nke steroidal, chlorpromazine dị elu, monoamine oxidase inhibitors: welie mmetụta hypoglycemic ma bulie ohere nke hypoglycemia. A na-atụ aro iji nlekọta glycemic na nhọrọ nke Gliclazide.
tetracosactide, glucocorticosteroids maka systemic na mpaghara (intraarticular, subcutaneous, cutaneous, rectal) iji: dịkwuo glucose ọbara na mmepe ga - ekwe omume nke ketoacidosis (ibelata na ndidi na carbohydrates). Jiri nlezianya jikwaa glycemic njikwa, karịsịa na mmalite nke usoro hypoglycemic, na mmezi nke glycazide,
beta₂-adrenomimetik (terbutaline, salbutamol, ritodrine): mụbaa glucose ọbara, yabụ, a gha nlezianya nyochaa ọkwa glucose ọbara. Nwere ike ịchọ nyefe onye ọrịa insulin,
gliclazide na ihe ndị ọzọ na - eme ka sulfonylurea: ọgwụ anticoagulants nwere ike ịbawanye mma, na-achọ ndozi dose.

Nyocha banyere Gliclazide

Dabere na nyocha, Gliclazide bụ onye ọrụ antidiabetic dị irè. Ugbu a, a na-eji ụzọ dị iche iche nke sulfonylureas nke ọgbọ nke abụọ, ebe ọ bụ na ha karịrị ọgbọ gara aga na ogo mmetụta hypoglycemic, ọ ga-ekwe omume nweta ụdị mmetụta ahụ mgbe ị na-edepụta obere usoro. Na mgbakwunye, ego otu a anaghị enwe ike ịkpata nsonaazụ.

Ndị ọkachamara n'ịgwọ ahụike na-egosi na n'oge biotransformation nke gliclazide, a na-ehibekwa metabolite, nke nwere mmetụta bara uru na microcirculation. Ọtụtụ nnyocha achọpụtala na ọgwụ ahụ na-ebelata ihe ize ndụ nke nsogbu microvascular (nephropathy, retinopathy), mmepe nke angiopathy. Na mgbakwunye, ọ na-eme ka njikọta nri dị mma, wepu akwara vaskụla. N'akụkụ a, nhọrọ nke Gliclazide bụ ezigbo maka nsogbu nke ọrịa shuga dịka ọdịda ọdịda na-adịghị ala ala, nephropathy, retinopathy na angiopathy.

Enwere akụkọ na afọ ole na ole (afọ 3-5) mgbe ịmalite ị drugụ ọgwụ ahụ, uche nke ọgwụgwọ na-ebelata. N'ụdị ndị ahụ, achọrọ nhọpụta hypoglycemic nnọchi anya.

Mbadamba nke Glyclazide

Nkwadebe ọnụ a na-etinye n'ọbara, nke bụ usoro nke usoro nke abụọ n’ọbara sulfonylurea, nwere ọtụtụ ọgwụ ọgwụ na-agwọ ọrịa. A na-enweta Glyclazide n'ụdị mbadamba 80 mg ma ọ bụ 30 na 60 mg yana mgbapụta agbanwetụ. Ogwu a gosipụtara na ịba uru, ya mere, a na - egosikarị ya iji mee ka glucose ọbara dị ọcha.

Mbadamba ụrọ 30 mg nke Glyclazide nwere okirikiri, dị larịị na-adị ọcha, enwere chamfer, agba ahụ na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke na-acha ọcha (odo ma ọ bụ isi awọ). Usoro ogwu nke 60 mg nọ n'ihe ize ndụ. Ihe na-arụ ọrụ bụ gliclazide. Nhazi nke ọgwụ:

gliclazide-30 ma ọ bụ 60 mg

silloon dioxide colloidal

sodium stearyl fumarate

Ihe ngosi maka ojiji

A na-eji ọgwụ Gliclazide mee ihe maka ụdị ọrịa shuga 2 na hyperglycemia. Ceptionnabata bụ nke bara uru ma ọ bụrụ na ọ dịcha uru ọgwụgwọ ọgwụ, usoro iji belata ndekasị anụ ahụ na mmega ahụ pụrụ iche. Glyclazide dị irè igbochi nsogbu nke ọrịa shuga nke ọrịa shuga 2: mmepe nke microvascular pathologies (ọrịa strok, infarction myocardial) yana nsogbu microcirculatory (retinopathy, nephropathy).

Ntụziaka maka iji Gliclazide

Mkpebi banyere usoro onunu ogwu maka ịbanye na hyperglycemia bụ nke dabere n’usoro nke usoro: afọ, ogo nke ọrịa shuga, yana shuga ọbara tupu iri nri na awa abụọ mgbe erichara nri. Usoro ọgwụgwọ akwadoro nke mbụ bụ 40 mg na nri. A na-atụ aro ị doụ ọgwụ a maka ndị ọrịa niile, gụnyere ndị agadi. Ọgwụ mbụ kwa ụbọchị bụ 80 mg. Ọzọkwa, dabere na parampat, nkezi nke 160 mg kwa ụbọchị. A na-eme ndozi usoro onunu na-eburu n'uche oge izu abụọ kacha nta.

Ihe kacha anabata ike ị nweta bụ - 320 mg. Ọ bụrụ n’ikpefere ịpụ ọgwụ ahụ, ịkwesighi ịba ụba dose ahụ n’echi ya. Usoro ọgwụgwọ maka ndị ọrịa agadi, yana ndị ọrịa nwere ọdịda gbasara akụrụngwa, adịghị iche. Shouldụ ọgwụ ahụ kwesịrị ịchịkwa glucose ọbara iji gbochie hypoglycemia (ịba ụba nke glucose).

Glyclazide MV 30 mg

-Kpụrụ Gliclazide gbanwetụrụ (MV) nke Gliclazide nwere ike ịdị site na 30 ruo 120 mg. N'ikuku na-ewere nri n'ụtụtụ. Ọ bụrụ n ’ịwụsị ọgwụ maka hyperglycemia, amachibidoro ịkwụ ụgwọ ịba n’ihu n’echi ya. A na-eme mkpebi usoro onunu ogwu n’otu n’otu. Imu mbu bu 30 mg. N'ihe banyere ọdịda nke nsonaazụ ahụ, dose ahụ jiri nwayọ (otu ugboro n'ọnwa) ruru 60, 90 na 120 mg. Enwere ike ịgbakwunye Gliclazide MB yana insulin. Ka anyị chee ngbanwe yiri nke a site na iwere Gliclazide 80 ruo Gilllazide MV 30 mg mgbe oke shuga gachara.

Usoro ire na ebe nchekwa

Ọgwụ a kwesịrị ịchekwa n'ebe gbara ọchịchịrị na-enweghị mmiri na okpomọkụ ọ bụla dị elu karịa ogo 25. Ekwesịrị ichebe Gliclazide site na ụmụaka. Ndụ shelf bụ afọ atọ. Relelị site na ndenye ọgwụ.

N'ime ụlọ ahịa ọgwụ ụlọ enwere ọtụtụ analogues nke Gliclazide. Offọdụ n'ime ha nwere otu ihe arụ ọrụ, akụkụ ọzọ na-enye ohere iji nweta otu ụdị ọgwụgwọ ahụ. Ọgwụ ndị a bụ analogues nke ọgwụ:

Glyclazide Canon,
Glidia MV,
Gluconorm,
Pịa
Glioral
Glucetam
Ọrịa mamịrị
Diabresid
Diagnizide.

Ngwa ọgwụ ọgwụ

Ọrịa hypoglycemic maka nchịkwa ọnụ. Emere ngwaahịa dika ihe sitere na usoro nke abuo nke sulfonylurea nke abuo. Na-enyere aka n'ịmepụta insulin site na mkpụrụ ndụ akwara. Ọ na-eme ka ahụrịị anụ ahụ dị elu na insulin. Na-eme ka oge ghara ịdị n’agbata nri na mbido insulin.

Usoro onunu ogwu na ihe ndi ozo banyere mbadamba nkume "Gliclazide"

Mgbe ọ batara n’afọ, ọgwụ na-agbaji ngwa ngwa n’olu ya. Ka awa anọ gachara, ọgwụ mgwara iri asatọ na-abanye n'ọbara ọbara. Ihe fọrọ nke nta ka ọ bụrụ 100% na-agwakọta na protein protein. Ọ na-agbari na imeju na-etolite metabolites na-enweghị ihe nwere hypoglycemic, mana naanị nwere ike imetụta microcirculation. Ọ na-apụta ya na mmamịrị n'ehihie.

Na nmalite ọgwụgwọ, a na-enye ọgwụ mg 80 mg otu ugboro kwa ụbọchị. Enwere ike iwere kacha nke 160-220 mg ugboro abụọ n'ụbọchị. Mbadamba ụta na-egbu egbu tupu nri. Ọzọkwa, usoro onunu ogwu dabere na oria ya na ogo mmebi nke pancreas. Nwere ike ịkekọrịta nnabata. A na-ewere otu mbadamba ihe na afọ na-enweghị isi, na awa abụọ mgbe nri gasịrị, ikwugharị usoro onunu ogwu. Etu esi eji "Glyclazide"? Ntụziaka maka ojiji. Ọnụahịa, ọgwụ analogues, usoro ọgwụgwọ kwesịrị - dọkịta ga-ekwu maka ihe a niile.

Mmekọrịta na ọgwụ ndị ọzọ

Mbadamba ọgwụ Glyclazide na-efunahụ mmetụta ya mgbe a na-ejikọ ya na ọgwụ ụfọdụ. Ihe ndị a bụ usoro pyrazolone, ọgwụ antibacterial sulfonamide, MAO inhibitors, theophylline, caffeine.

Site na iji concoitant na ndị na-abụghị nhọrọ beta-mgbochi, mmepe nke hypoglycemia na-abawanye, tachycardia na aka na-ama jijiji, ịchafụ, karịsịa n'abalị, nwere ike ịpụta.

Mgbe ị na-eji ngwaahịa ọgwụ "Cimetidine" na plasma, ọdịnaya nke mbadamba "Gliclazide" na-abawanye. Nke a nwere ike ibute nnukwu hypoglycemia. Site na nhazi oge nke mbadamba ihe ndị Glyclazide na ọgwụ Veropomila, ọ bara uru ịchịkwa ọkwa shuga ọbara.

Ọzọkwa, yana iwere GCS, mbadamba Glyclazide na-ebelata ihe hypoglycemic ha. Ọgwụ ndị dị ka ọgwụ ụkwara ume ọkụ, barbiturates, estrogens, na ụfọdụ ọgwụ mgbochi TB. Ya mere, ọ bara uru nyocha ahụ nke ọma tupu ị takingụ ọgwụ "Gliclazide." Ntụziaka maka ojiji, ọnụahịa, analogues, mmetụta ndị ọzọ ọ nwere ike ịmasị - ekwesịrị ịma nke a tupu oge eruo.

Ihe ngosiputa maka iwere mbadamba Glyclazide

Edere ọgwụ ahụ maka ọrịa shuga nke ụdị nke abụọ na-agafeghị oke, mgbe enweghi nnweta insulin. Ọzọkwa maka mgbochi maka ọrịa microcirculatory. Ejiri ọgwụ n’okpuru nlekọta nke dibịa. Ikwesiri ime nyocha nke glukos. Jide n'aka na ị ga-agbaso nri mgbe ị na-agwọ ya, belata oriri nke nnu na carbohydrates. Jụ iji ntụ ọka na shuga.

Gliclazide mv

Mbadamba ụrọ Glyclazide mv egosiputala nke ọma. Ntuziaka maka iji mee ihe ga-agwa banyere contraindications na mmetụta dị n'akụkụ ọgwụ a. A na-eji ya agwọ ọrịa ọrịa mellitus na-abụghị insulin na-aga n ’ịdị nwayọ. Nweghị ike ị drinkụ ọgwụ a maka ọrịa shuga nke ụdị nke mbụ, yana ọrịa pathologies imeju na akụrụ. N’ime oge ịtụrụ ime na n’ara ara, a machibidoro ị theụ ọgwụ ahụ ike.

Usoro ọgwụgwọ kwesịrị ijikọ ya na nchịkwa shuga. N'ime mmetụta ndị dị na ya, ọgbụgbọ, ọgbụgbọ, ọgbụgbọ, na mgbu afọ. N'ọnọdụ ndị a na-adịghị ahụkebe, anaemia na leukopenia tolitere. Site na mmeghachi omume nfụkasị ihe ndị metụtara mbadamba mbadamba, ihe ọkụ ọkụ nwere ike ịpụta. Gliclazide mv nwere otutu ogwu nke enweghi nkwekorita. Ndị a bụ diuretics, barbiturates, estrogens, aminophylline ọgwụ. N'ezie, a ga-atụle ntuziaka maka ojiji tupu ịmalite ọgwụgwọ na mbadamba Glyclazide mv. Ọnụahịa nke ngwaahịa ahụ anaghị agafe 500 rubles.

Ogwu hypoglycemic ọgwụ. Mbadamba acha ọcha, convex ubé. N'akụkụ abụọ a, e nwere ihe ịrịba ama nke DIA 60. Nke a na-egosi na enyere ikike ọgwụ a. Nke a bu ezigbo uzo iji ghaa ogwu.

Ihe mejupụtara ọgwụ ahụ gụnyere gliclazide umi. Edere ọgwụ a naanị maka ndị okenye. Ikwesiri ị drinkụ otu mbadamba otu ugboro n’ụbọchị. A na-eme nke a nke ọma mgbe nri ụtụtụ. Dabere n'ụdị ọrịa shuga na ọnọdụ izugbe, enwere ike ịba ụba usoro a gaa mbadamba abụọ kwa ụbọchị. Mpempe akwụkwọ nke Glyclazide nwere otu usoro usoro ọgwụgwọ ahụ. Ntuziaka maka iji kọwaa ihe niile n'ụzọ zuru ezu.

Mgbe ị na-eji ọgwụ dị elu, hypoglycemia nwere ike ịmalite. N’ime ọnọdụ a, ọ dị mkpa ka achọ enyemaka n’aka ọkachamara. Ọ nwere ụdị contraindications niile na nsonaazụ ya dịka ọgwụgwọ "Gliclazide mv". Ntụziaka maka ojiji, ọnụahịa, nyocha - ihe ndị a kwesịrị ịmụ tupu ịmalite ọgwụgwọ.

Nyocha banyere ọgwụ "Gliclazide"

Ọtụtụ mgbe, ịnwere ike ịnụ nkwupụta dị mma gbasara ọgwụ. Ndị ọrịa rịbara ama na ọgwụ na-enyere aka ịchịkwa shuga ọbara ma na-enye aka na ahụike nkịtị. Naanị ihe na-adabaghị adaba bụ na ekwesịrị ị medicineụ ọgwụ ahụ dabere na atụmatụ ahụ. Dodoụbiga mmanya ókè pụrụ ịdị ize ndụ.

Ọnụahịa nke Gliclazide na ụlọ ahịa ọgwụ

Ndebanye aha ọgwụ ahụ emebiela, yabụ amataghị ọnụahịa nke Gliclazide. Odika onu ahia nke analogues:

Gliclazide MV - 115–144 rubles. Kwa mbadamba 60 nke mbadamba 30 nke 30 mg ọ bụla,
Glidiab - 107-1515 rubles. Kwa mbadamba 60 nke mbadamba 80 nke 80 kwa,
Diabeton MV - 260-347 rubles. kwa mbadamba 30 nke mbadamba 60 nke 60 mg.