Kedu ihe nwere ike dochie Fraxiparin: analogues na ilu nke ọgwụ ahụ

N'ime usoro ahụike, ndị dọkịta nke ọtụtụ ọpụrụiche (hematologists, obstetrician-gynecologists, dọkịta na-awa) na-ezute ikpe mgbe ụfọdụ na-achọ ka ekpughere ya na sistemụ ahụike ahụ. Ruo ogologo oge, ndị dọkịta ejirila ọgwụ ndị nwere ike ịgbanwe ọnọdụ arụ ọrụ nke ọbara coagulation. Ka oge na-aga, ọgwụ ndị dị otú ahụ na-abawanye ụba, ogo ha, ịdị irè ya na, ihe dị mkpa bụ na nchekwa ha na-abawanye. Ugbu a, otu n'ime ọgwụ anticoagulant kachasị bụ Clexane, agbanyeghị, enwere ọtụtụ ọnọdụ ebe ebumnuche ya agaghị ekwe omume.

N'ọnọdụ ebe onye ọrịa ahụ adabaghị ọgwụ ahụ maka ihe ụfọdụ, ọ bụ naanị ọkachamara ruru eru ka a ga-ahọrọ analogues maka oge a ga-ahọpụta. Can nweghị ike ịgbanwe ọgwụ ahụ n’onwe gị, ebe nke a nwere ike ibute mmerụ ahụ na-enweghị atụ na ahụike.

Ozi ọgwụ gbasara izugbe

Ọ bụ ọgwụ nwere mmetụta anticoagulant nwere mmetụta. Ihe mejupụtara ọgwụ a akọwapụtara gụnyere Enoxaparin sodium, nke na-arụ ọrụ dị ka ihe bụ isi na-arụ ọrụ nke na-emetụta mmetụta ọgwụgwọ niile na ahụ. Ngwọta ọgwụ dịnụ dị site na 20 ruo 100 milligrams. Ahotara itinye uche dị mkpa na-ewere akaụntụ nke pathology na plọg nke onye ọrịa ọ bụla.

Usoro nke ihe a dabere na ikike igbochi ụfọdụ ihe coagulation (nke abụọ, nke asaa na nke iri). Yabụ, ọgwụ ahụ nwere ike ịkwụsị itisa nke ọgbụgba ọbara na thrombus. Ihe mgbochi nke ihe ndị dị n’elu a bụ ihe kpatara mbido antithrombin 3, nke dị n’ọbara.

Ọgwụ a dị n'ụdị edozi edozi, doziri ya na sirinji pụrụ iche maka nchịkwa subcutaneous. Ofdị ntọhapụ a na-eme ka ojiji nke ọgwụ ahụ ike ma na-eme ka ndị ọrịa nwee ike ịkụnye ya n'onwe ha, ebe ha na ndị ọrụ ụlọ ọgwụ nweela ọzụzụ dị mkpirikpi.

Edere ọgwụ a maka ịgwọ nnukwu thrombosis nke nnukwu nsonye. Ọzọkwa, ojiji a na-agu n'onye ezi omume dị ka prophylaxis n'ahụ ndị ọrịa nwere nnukwu nsogbu nke thrombotic.

N'ime ndị nọchiri anya, anyị nwere ike ịmata ọdịiche ahụ ọgwụ ndị nwere otu ihe mebere, mana ndị ụlọ ọrụ ọgwụ ndị ọzọ na-emepụta, yana ndị nwere ụdị dị iche iche, mana nwee mmetụta yiri nke Clexane na ahụ.

Imeghari nwere ike ịdị mkpa ma ọ bụrụ na onye ọrịa ahụ ekpughela ihe ịrịba ama nke ekweghị ibe ya na ọgwụ, mmetụta ọ bụla na nsogbu. Ọzọkwa, nhọrọ nke analog dị ọnụ ala karịa mgbe onye ọrịa na-enweghị ike ịkwụ ụgwọ ọgwụ enyere ya.

Clexane ma ọ bụ Fraxiparin: nke ka mma

Fraxiparin bu ihe anticoagulant. Agbanyeghị, ọ nwere calrop nadroparin, nke na-ezo aka na heparins dị ala dị ala. A na enweta ọgwụ a n'ụdị sirinji nke nwere nkwadebe iji gaa. Uru a na-ejighị n'aka nke Fraxiparin bụ ego dị ala, nke a na-eme ka ọ bụrụ ego maka ndị ọrịa buru ibu. Ihe ngosi maka nhọpụta ma ọgwụ abụọ atụnyere

Gemapaksan ma ọ bụ Kleksan: ihe ị ga - ahọrọ

Drugs drugsụ ọgwụ abụọ a na ibe ha yiri ibe ha, ebe ha dabere na otu ihe eji arụ ọrụ (enoxaparin). Ndepụta nke ihe na contraindications maka etu esi akọwa bụ otu. Gemapaxan dị ọnụ ala karịa, n'agbanyeghị eziokwu ahụ bụ na emepụtara ya na mba ofesi ()tali). Enweghị data a pụrụ ịdabere na ya nke ọgwụ ndị a dị irè ma dị nchebe. Ndị dọkịta na-ejikarị ọgwụ ndị a arụ ọrụ na-arụ ụka na mmetụta ha bụ otu. Ọgbaghara na-eme ihe dịka otu ugboro na ọgwụ mbụ na nke abụọ.

Atụmatụ ndakọ nke Pradaxa na Kleksan

Ihe mejupụtara Pradaxa gụnyere ihe na-arụ ọrụ dabigatran etexilate, bụ nke otu ndị otu mgbagha thrombin kpọmkwem. Pradaxa na-abanye ahụ mmadụ na arụ ọrụ adịghị arụ ọrụ. Mgbe ọ gbasasịrị site na eriri afọ ma banye na mgbasa ozi nke usoro, a na-agbanye ya na hepatocytes n'ihi ogige enzymatic na ogige dị n'ime ha.

N'ihi ya, ndị ọrịa edepụtara Pradax ekwesịghị inwe ọrịa imeju na-arụ ọrụ, ebe nke a ga-enwe mmetụta ọzọ na-emebi imeju.

Dị Mkpa! Uru Pradaxa bụ ohere nke nchịkwa na-abụghị nke a na-alụ ọgụ (dị na ụdị mbadamba).

Heparin ma ọ bụ Clexane: nke ka mma

Ihe na-arụ ọrụ nke Clexane bụ usoro nke Heparin. Ya mere, Heparin na-egosi na ọ dị ka ihe dị arọ, yana Clexane dịkwa obere mkpanaka. Ejiri usoro Clexane mepụta mgbe emechara, yabụ ọgwụ a dị nchebe ma nwekwuo arụmọrụ, ọ dịkwa obere ka ọ duga mmepe nke mmetụta ndị achọghị.

Ekwesiri icheta na ihe ize ndụ nke ịmalite ịrịa ụdị ọrịa a site na iji heparin, dị ka autoimmune thrombocytopenia, na-adịgide mgbe ọ na-edepụta akwụkwọ ikike dị na molikula dị ala.

Zibor dị ka analog

Akụrụngwa na-arụ ọrụ nke Zibor bụ nnu sodium nke heparin dị mkpụmkpụ obere (sodium bemiparin). A na-eji ọgwụ a eme ihe n'ọtụtụ ịwa ahụ na nephrology (a na-enye ya ndị ọrịa na-anara ụdị akụrụngwa extracorporeal na akụrụngwa nwa). Usoro nke ihe Zibor yiri nke a kpamkpam, ebe ọgwụ a na-egbochi thrombosis n'ihi nkwụsị nke coagulation cascade. Enweghị ike iji Zibor mee ihe na nwata n'ihi eziokwu ahụ bụ na enwebeghị nnyocha ọmụmụ zuru ezu banyere mmetụta ọgwụ a na ahụ ụmụaka.

Enixum na Clexane: ntụnyere ọgwụ

Ngwakọta nke ọgwụ ndị atụnyere na-agụnye otu kemịkal kemịkalụ, nke na-ekpebi oke myirịta ọgwụ ndị a dị. Enixum yana Clexane dị n'ụdị injectable ezubere maka nchịkwa subcutaneous. Ogwu ahu di na usoro ogwu iri di iche iche, nke gha enyere dọkịta aka ka o jiri nlebara anya nke oma nye onye oria obi okwu.

Ọtụtụ mgbe, Enixum ka a na-enye ka ọ bụrụ ihe ngosipụta nye ndị ọrịa nke ụlọ ọgwụ ịwa ahụ bụ ndị emerela ọtụtụ ọrụ (ọkachasị usoro ịwa ahụ na usoro akwara).

Enoxaparin sodium dị ka analog nke Clexane

Ihe mejupụtara ọgwụ abụọ ahụ bụ otu, yabụ, ihe niile egosipụtara na contraindications maka iji ha bụ otu. Abụọ Enoxaparin sodium na Clexane bụ nke a na-ahụ na ntinye subcutaneous, nke abụghị usoro dị oke mma nye ọtụtụ ndị ọrịa.

N'ihe banyere ebe enwere ike ịhapụ ọgwụ ngwa ngwa, Enoxaparin sodium agaghị enwe ike dochie ya. Ọmụmụ ihe nke nwere ike ịsị nke ọma ọgwụ ọgwụ ndị a ka emebeghị, mana na omume ha na arụmọrụ ha fọrọ nke nta ka hà nhata.

AhaỌnụahịa
Clexanesite na 176.50 rub. ruru 4689.00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
Evropharm RUMkpokọta clexane 20 mg / 0.2 ml 1 sirinji 176.50 rub.Anolọ ọrụ Sanofi Winthrop
Evropharm RUMkpokọta clexane 40 mg / 0.4 ml 1 sirinji 286.80 rub.Anolọ ọrụ Sanofi Winthrop
Evropharm RUMkpokọta Clexane 20 mg / 0.2 ml 10 sirinji 1725.80 nkp.Dọkịta ọgwụ / UfaVita
Evropharm RUMkpokọta clexane 80 mg / 0.8 ml 10 sirinji 4689.00 rub.Dọkịta ọgwụ / UfaVita
ego kwa otu - 2
Ọgwụ ahịa ọgwụClexane (sirinji 60mg / 0.6ml Nke 2) 632.00 rubFrans
ego kwa mkpọ - 10
Ọgwụ ahịa ọgwụClexane Syringe 20mg / 0.2ml Nke 10 1583.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 40mg / 0.4ml Nke 10 2674.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 80mg / 0.8ml Nke 10 4315.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 80mg / 0.8ml Nke 10 4372.00 nkp.RUSSIA
Pradaxasite na 1777,00 rub. ruo 9453.00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
Evropharm RUpradax 150 mg 30 nkpisi 1876.60 rub.Beringer Ingelheim Pharma GmbH & Co.KG
Evropharm RUpradax 75 mg 30 okpu 1934.00 rub.Beringer Ingelheim Pharma GmbH & Co.KG
Evropharm RUpradax 150 mg 60 nkp 3455.00 rub.Beringer Ingelheim Pharma GmbH & Co.KG
Evropharm RUpradax 110 mg 60 nkp 3481.50 rub.Beringer Ingelheim Pharma GmbH & Co.KG
ego kwa mkpọ - 30
Ọgwụ ahịa ọgwụPradaxa (okpu. 150mg Nke 30) 1777.00 rub.Jamanị
Ọgwụ ahịa ọgwụPradaxa (okpu. 110mg Nke 30) 1779.00 rub.Jamanị
Ọgwụ ahịa ọgwụPradaxa (okpu. 75mg Nke 30) 1810.00 rub.Jamanị
ego kwa mkpọ - 60
Ọgwụ ahịa ọgwụPradaxa (okpu. 150mg Nke 60) 3156.00 rub.Jamanị
Ọgwụ ahịa ọgwụPradaxa (okpu. 110mg Nke 60) 3187.00 rub.Jamanị
ego kwa mkpọ - 180
Ọgwụ ahịa ọgwụPradaxa (okpu. 150mg Nke 180) 8999.00 rub.Jamanị
Ọgwụ ahịa ọgwụPradaxa (okpu. 110 mg Nke 180) 9453.00 rub.Jamanị
Fraxiparinsite na 2429,00 rub. ruru 4490,00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
Evropharm RUSolxiparin subcutaneous ngwọta 3800 IU / 0.4 ml 10 sirinji 3150.00 rub.Nanolek LLC
Evropharm RUSolxiparin subcutaneous 5700 IU / 0.6 ml 10 sirinji 4490.00 rub.Aspen Notre Dame de Bondeville / LLC Nanolek
ego kwa mkpọ - 10
Ọgwụ ahịa ọgwụFraxiparin (sirinji 2850ME anti-HA (9.5 puku IU / ml) 0.3ml Nke 10) 2429.00 rub.Frans
Ọgwụ ahịa ọgwụFraxiparin (sirinji 2850ME anti-HA (9.5 puku IU / ml) 0.3ml Nke 10) 2525.00 rub.Frans
Ọgwụ ahịa ọgwụFraxiparin (sirinji 3800ME / ml mgbochi-HA (9.5 puku IU) 0.4ml Nke 10) 3094.00 rub.Frans
Ọgwụ ahịa ọgwụFraxiparin (sirinji 3800ME / ml mgbochi-HA (9.5 puku IU) 0.4ml Nke 10) 3150.00 rub.Frans

Mpempe ndị ọzọ dị ọnụ ala

Clexane bụ ọgwụ dị oke ọnụ, ọkachasị mgbe ị tụlere na ịkwesịrị ịkwụ ụgwọ ya na ọmụmụ niile. Na-esote, anyị na-enye ndepụta nke ọgwụ nwere ike dochie ọgwụ a, mana nwee ọnụ ala dị ala:

AhaỌnụahịa
Fenilinsite na 37,00 ite. ihe ruru 63,00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
ego kwa mkpọ - 20
Ọgwụ ahịa ọgwụPhenilin (mbadamba 30mg Nke 20) 37,00 iteUkraine
Evropharm RUphenylin 30 mg 20 mbadamba 63,00 iteHealth FC LLC / Ukraine
Clexanesite na 176.50 rub. ruru 4689.00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
Evropharm RUMkpokọta clexane 20 mg / 0.2 ml 1 sirinji 176.50 rub.Anolọ ọrụ Sanofi Winthrop
Evropharm RUMkpokọta clexane 40 mg / 0.4 ml 1 sirinji 286.80 rub.Anolọ ọrụ Sanofi Winthrop
Evropharm RUMkpokọta Clexane 20 mg / 0.2 ml 10 sirinji 1725.80 nkp.Dọkịta ọgwụ / UfaVita
Evropharm RUMkpokọta clexane 80 mg / 0.8 ml 10 sirinji 4689.00 rub.Dọkịta ọgwụ / UfaVita
ego kwa otu - 2
Ọgwụ ahịa ọgwụClexane (sirinji 60mg / 0.6ml Nke 2) 632.00 rubFrans
ego kwa mkpọ - 10
Ọgwụ ahịa ọgwụClexane Syringe 20mg / 0.2ml Nke 10 1583.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 40mg / 0.4ml Nke 10 2674.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 80mg / 0.8ml Nke 10 4315.00 rub.Jamanị
Ọgwụ ahịa ọgwụClexane Syringe 80mg / 0.8ml Nke 10 4372.00 nkp.RUSSIA
Fragminsite na 2102.00 rub. ruru 2390,00 rub.zoo lee ọnụahịa n'uju
Lọ ọgwụAhaỌnụahịaEmeputa
Evropharm RUframmin injection maka mkpụrụ osisi 2500 IU / 0.2 ml 10 2390.00 rub.Vetter Pharma-Fertigung GmbH / Pfizer MFG
ego kwa mkpọ - 10
Ọgwụ ahịa ọgwụFragmin (sirinji 2500ME / 0.2ml Nke 10) 2102.00 nkp.Jamanị

International Nonproprietary Aha

Aha ochie a na-akpọ Fraxiparin, nke na-egosipụta ihe mejupụtara ọgwụ ọgwụ ahụ bụ calcium Nadroparin, aha mba ụwa bụ Nadroparinum.

Ọgwụ Fraksiparin 0.3 ml

Otutu aha ahia ogwu nile, nke otutu aha jikotara aka, nwere otu aru ahu na ihe ndi mmadu na eme.

Na mgbakwunye na aha, ọdịiche dị n'etiti ọgwụ dị iche iche nke onye nrụpụta dị na usoro onunu ogwu, yana ihe mejupụtara nke ndị na-ahụ maka ọgwụ na ndị na-ekewapụ ọgwụ na kemịkal na-anọpụ iche na ọgwụ ahụ.

Emeputa

A na-emepụta ọgwụ a na Fraxiparin na France n'ụlọ ọrụ mmepụta ihe nke bụ nke abụọ na-emepụta ọgwụ na Europe, GlaxoSmithKline, onye isi ụlọ ọrụ ya dị na London.

Ma, ọgwụ a dị oke ọnụ, yabụ ụlọ ọrụ ọgwụ na-emepụta ọtụtụ analogues.

Ndị otu ndị ala dịkarịsịrị ọnụ gụnyere:

  • Nadroparin-Farmeks nke Farmeks-Group (Ukraine) mepụtara,
  • Novoparin rụpụtara site na Genofarm Ltd (UK / China),
  • Flenox mepụtara site n'aka PAO Farmak (Ukraine),

A na-emepụta ngwaahịa ndị yiri ya site na ọtụtụ ụlọ ọrụ ọgwụ na India na European. Dabere na mmetụta dị n'ahụ ahụ, ha bụ analogues zuru oke.

Omume ọgwụ

Calcium nadroparin bụ heparin dị ala nke na-egbu ala (NMH) nke enwetara site na heparin, bụ glycosaminoglycan nke nwere ogo molecule dị 4300.

O gosiputara ikike di elu nke ijikọ protein protein Plasma na antithrombin III (AT III). Njikọ a na - eduga n'ịgba mgbochi nke ihe Xa, nke a bụ n'ihi oke ike antithrombotic nwere nadroparin.

Otherzọ ndị ọzọ na-enye nsonaazụ antithrombotic nke nadroparin gụnyere ịgbalite mgbochi anụ ahụ na-egbochi ntụgharị (TFPI), ịgbalite fibrinolysis site na ntọhapụ nke onye na - eme ka plasminogen anụ ahụ na mkpụrụ ndụ endothelial, yana ịgbanwe ihe ndị dị na rheological ọbara (iwetula viscosity ọbara na ịbawanye ike nke platelet na membranes granulocyte).

A na-amata Calrop nadroparin site na ihe mmegide dị elu karịa nke ahụ ma e jiri ya tụnyere ihe mgbochi IIa ma ọ bụ ọrụ antithrombotic ma nwee ma ọgwụ antithrombotic dị nso ma dị ogologo.

E jiri ya tụnyere heparin na-adịghị arụ ọrụ, nadroparin nwere obere mmetụta na platelet na nchịkọta, yana mmetụta dị ala na hemostasis bụ isi.

N'ime usoro onyonyo prophylactic, nadroparin anaghị ebute mbelata nke APTT.

N'ime usoro ọgwụgwọ n'oge arụ ọrụ kachasị, mmụba na APTT ruo uru 1.4 dị elu karịa ọkọlọtọ ahụ ga-ekwe omume. Ogologo oge dị otú a na-egosipụta nsị antithrombotic mmetụta nke calcium nadroparin.

Mlọ ọgwụ

A na-ekpebi ihe ndị dị na Pharmacokinetic na ntọala nke mgbanwe na ọrụ ihe mgbochi ọgwụ nke plasma.

Mgbe etinyere sc nchịkwa nke Cmax na plasma n'ime awa 3-5, nadroparin na-abanye kpamkpam (ihe dịka 88%). N'iji / ewebata izizi XA kachasị rụọ ọrụ na-erughị nkeji iri, T1 / 2 bụ ihe dịka awa 2

Ọ bụ metabolized n'ime imeju site na nkụda mmụọ na depolymerization.

Mgbe nchịkwa SC T1 / 2 dị ihe dịka awa 3.5. Agbanyeghị, ọrụ anti-Xa na-adịgide ma ọ dịkarịa ala awa 18 mgbe agba ọgwụ nadroparin na 1900 anti-XA ME.

Mpempe usoro onunu ogwu

Ogwu ahu di n’udi isi-ya. Dabere na onye nrụpụta na ụdị dịgasị iche iche, enwere ike ịchọta nhọrọ ọnụọgụ ọgwụ.

Kacha nkịtị bụ onunu ogwu nke 0.2, 0.3, 0.6 na 0.8 milliliters. Enwere ike inye ụlọ ọrụ mmepụta nke ụlọ ọrụ German Aspen Pharma na usoro nke 0.4 milliliters.

Na mpụga, nsị a bụ mmiri anaghị agba mmanụ, nke enweghị agba ma ọ bụ edo edo.Ọgwụ nwekwara njiri mara mma. Otu njiri mara nke Fraxiparin bu na enyeghi uzo a ka ampoules nke ndi n’enweghi nke oma mara, choro zuta nke eji eji achoro ya nke oma kwesiri ya na ufodu uzo tupu igba ya.

A na-ere ọgwụ ahụ na sirinji sirinji pụrụ iche, dị njikere maka ojiji. Iji nye ntụtụ, ọ zuru iji wepu okpu nchebe na agịga ma pịa na ọkpọ ahụ.

Isi ihe na-arụ ọrụ

A polysaccharide dịpụrụ adịpụ site na imeju bụ anticoagulant dị irè.

Ozugbo n'ọbara, heparin malitere itinye aka na cationic saịtị nke tri-antithrombin.

N'ihi nke a, ụmụ irighiri antithrombin na-agbanwe ihe ha nwere ma mee ihe na enzymes na protein nke na-akpata coagulation ọbara, ọkachasị, na thrombin, kallikrein, yana protein nchebe.

Ka ihe ahụ wee rụọ ọrụ na-arụsi ọrụ ike, a na-ekewa ngwa ngwa “ogologo” polymer ya n’ime mkpụmkpụ site na depolymerization n’okpuru ọnọdụ pụrụ iche n’elu akụrụngwa dị mgbagwoju anya.

Ime analogues

Ọgwụ Fraxiparin na-ejikarị afọ ime.

N'ezie, n'oge a, n'ihi mgbanwe dị iche iche na oke nke homonụ, akụrụngwa nke ọnụọgụ ọbara na-abawanye, nke nwere ike ibute ibu arọ. Kedu ụdị analogues nke ọgwụ a na-anabata iji buru nwa ebu n’afọ?

Ọtụtụ mgbe, a na-eji Angioflux - ngwakọta nke ụmụ irighiri ihe nke heparin, nke amịpụtara site na mucosa nke dị warara eriri afọ nke ezì ụlọ. Ma ahiri a na -ekwu ede na ụzọ dị irè maka ịgba ntụtụ dị.

Analog ọzọ na-ejikarị afọ ime bụ ịba ọcha n'anya. Dabere na mejupụtara ihe eji arụ ọrụ, ọ bụ analog nke Fraxiparin zuru oke, agbanyeghị, ọ dị iche n'ụdị usoro onunu ogwu. N'adịghị ka nke ikpeazụ, hepatrombin dị n'ụdị ude maka iji mpụga.

N'ikpeazụ, nkwadebe Wessel Douay F, nke nwere ngwakọta nke polysaccharides - glycosaminoglycans, nwekwara mmetụta yiri ya na Fraxiparin. Nlekọta ha na-egbochikwa mkpụrụ okwu coagulation ọbara X n'otu oge ahụ ịgbalite prostaglandins yana mbelata nke fibrinogen n'ime ọbara.

Ihe analogues na-efu

O bu ihe nwute, dika otutu ndi Europe, Fraxiparin di oke onu ahia. Agbanyeghị, enwere analogues dị ọnụ ala nke na - enye ohere maka mgbochi na ọgwụgwọ nke ngosipụta nke thrombotic ma na - echekwa ego. Ihe atụ kachasị dị oke ọnụ nke ọgwụ a bụ ọgwụ ndị emepụtara na China, India na CIS.

Ngwọta ogwu nwoke nke Enoxaparin-Farmeks

Otu ogwu nwere aha ahia Eneksaparin-Farmeks nke sitere na Ukraine. N'ime nkwadebe nke ụlọ ọrụ “Farmeks-Group”, isi ihe na - arụ ọrụ bụ co-molekụla, ya bụ, adịghị n'otu, heparin.

Ọ dị oke ọnụ karịa nke Enoxarin nke Biovita Laboratories mepụtara - nnukwu otu ụlọ ọrụ na-ahụ maka ndị India. Ọ na - abata na sirinji pụrụ iche a na-eji arụ ọrụ ma nwee ihe yiri ya - ọgwụ hepatarin “dị mkpụmkpụ”.

Iji dochie anya Fraxiparin bụ ọgwụ a na-akpọ Clexane. Ndị na-ahụ maka ọgwụ French na-arụ ọrụ na mmepụta, nke na-ekwe nkwa ịdị elu nke ọgwụ na nchekwa nke nchịkwa ya.

Ọdịiche nke Fraksiparin si Kleksan

A na-amata Clexane site na ọnụego dị elu, mana ọ bụ n'ọtụtụ ndị dọkịta na - eme ya na-ewere ya na a na - ewere ya na ọ bụ ọgwụgwọ kachasị mma ma dị irè n'oge afọ ime.

Ohere iji Clexane dị ogologo oge, dabere na Fraxiparin, na-enwe ahụ.

Ọkpụkpụ Clexane

Dika omume ndi mmadu na acho, odi nkpa igwa Fraxiparin ugboro abuo. N'otu oge ahụ, Clexane nwere mmetụta n'ime awa 24, nke na -ebelata ọnụ ọgụgụ nke inje na ọkara.

Nyere na a na-ewere ọgwụ a ogologo oge, mbelata ọnụọgụ kwa ụbọchị nke ọgwụ inje na-ahọrọ n'usoro nke nkasi obi na ọdịmma.

Ma ọ bụghị ya, ọgwụ ndị a yiri nnọọ ma ọdịiche adịghị n'ụdị ntọhapụ, ma ọ bụ na ihe nọ n'ọrụ, ma ọ bụ na mmeghachi omume nke anụ ahụ na nhazi ha.

Fraxiparin ma ọ bụ Heparin

Kaosinadị, ugbu a ọ na-emewanye ka Fraxiparin na analogues nọchiri ya.

Echiche nke Heparin gafere n’ihe mgbochi Placental ma nwee ike nwee mmetụta dị njọ na nwa ebu n’afọ bụ ihe ezi uche na-adịghị na ya.

Dabere na ọmụmụ, ma Fraxiparin na Heparin egosighi ike ịbanye na Plasenta ma nwee ike inwe mmetụta dị njọ na nwa ebu n’afọ naanị ma ọ bụrụ na agafere oke usoro onunu ogwu.

A kọwara njupụta nke Fraxiparin na usoro ọgwụgwọ ọhụụ bụ naanị site na ịdị mma nke iji ya - ma ọ bụghị ọgwụ ndị ahụ nwere mmetụta zuru oke.

Fraxiparin ma ọ bụ Fragmin

Fragmin, dị ka ọgwụ ndị ọzọ dị na otu ahụ, nwere heparin pere mpe. Agbanyeghị, eji Fragmin mee ihe dị ka coagulant n'ozuzu, n'adịghị ka Fraxiparin, nke etolitere maka iji mee n'oge ime.

Mbibi nke Fragmin

Ọ bụrụ na nke ikpeazụ ahụ nwere ngwakọ calcium nke ihe na-arụ ọrụ, mgbe ahụ Fragmin nwere nnu sodium nke heparin polymerized. Enwere ihe akaebe na nke a, Fragmin nwere mmetụta dị njọ n'ahụ ahụ.

Ka ị na-a drugụ ọgwụ a, ọbara ọgbụgba site na akwara ọbara dịkarịsịrị ụba. Nke kachasị, iji Fragmin nwere ike bute imi afọ, yana ị na-agba ọbara ndị ọrịa.

Vidiyo ndị metụtara

Etu ị ga-esi mee ka obere mkpụrụ ọgwụ nke Clexane:

Na mkpokọta, enwere mkpokọta analogues zuru ezu nke Fraxiparin, nke dị iche na ọnụ ahịa ka mma ma ọ bụ na ogologo oge, ma na-enye gị ohere ịchekwa ego site na iguzogide nnabata ọnya ọbara nke hụrụ n'oge ịtụrụ ime ma ọ bụ nsogbu enzymatic.

  • Na-akwadokwa ọkwa shuga ruo ogologo oge
  • Weghachi nrụpụta insulin nke pịkụl

Mụtakwuo. Ọ bụghị ọgwụ. ->

Isoprinosine® - analogues dị ọnụ ala, ọnụahịa ndị Russia na ndị na-ebubata mbubata

Isoprinosine Iriprinosine dị Irè ma baa uru

N'oge mgbụsị akwụkwọ-oge oyi, ahụ mmadụ na-abụkarị ihe ọghọm n'ọrịa dị iche iche.

N'oge a, onye ọ bụla kwesịrị ịnwe ọgwụ mgbochi siri ike n'ụlọ. Otu ọgwụ dị otú ahụ bụ Isoprinosine®.

Ogwu ahu di ezigbo uto, mana obughi ndi oria ga ajuju onu ahia ya n’ulo ogwu. Ya mere, ọ bụ ihe amamihe dị na ya ịtụle ihe analogues ọgwụ na-adịghị ọnụ.

Mmetụta ọgwụ

Isoprinosine bụ ọgwụ immunostimulating nwere mmetụta mgbochi. Ọ mejupụtara acid 4-acetamidobenzoic na inosine.

Akụkụ nke mbụ na - eme ka ọbara na ihe ndị dị mkpa dị mma site na akpụkpọ ahụ. Site na ya, ọrụ nke lymphocytes na-abawanye, na ngosipụta nke ndị na-anabata membrane na-akpali. Mkpụrụ ndụ Lymphocyte na-ebelata ọrụ n'ihi ekpughere glucocorticoids, ma gụnye thymidine na ha.

Akụkụ nke abụọ na-akpali ọrụ nke cytotoxic lymphocytes, na-egbochi guzobe cytokines na-akpata nsogbu.

Inosine na-eguzogide ọgwụ nje nke herpes simplex, measles, influenza A, B. Ihe kachasị egosi bụ ọgwụgwọ nke ọrịa herpes.

N'oge nchịkwa ọgwụ ahụ, enwere ọgwụgwọ ngwa ngwa nke ọnya ọnya karịa ndị ọzọ, ụdị ọgwụgwọ ọdịnala.

Ihe nloghachi n'ụdị ọdịdị nke blisters ọhụụ, usoro mbuze na edema bụ eleghi anya. N'okwu a, ịmalite ọgwụgwọ n'oge n'oge dị mkpa, nke ga-ebelata ogo na oge ọrịa ahụ.

Ihe ngbanwe

Ekwesịghị iwere:

  • Ọ bụrụ na nsogbu dị na insimi nke ngwaọrụ ahụike,
  • Ndị ọrịa nwere gout
  • Ndị mmadụ nwere ọrịa ọrịa dị iche iche,
  • Na urolithiasis,
  • Inmụ nwanyị nọ n'ọnọdụ ha na oge ị breastụ ara,
  • Undermụaka na-erubeghị afọ atọ ma na-erughị 20 n'arọ.

O nwere ike ọghọm ya

  • Malfunctions nke Central ụjọ - isi ọwụwa, nweta ihe ngwa ngwa nke mmetụta ike ọgwụgwụ,
  • Ọrụ a na-ejighị n'aka nke eriri afọ - nsogbu na agụụ, vomiting, afọ ọsịsa,
  • Nsogbu nke akwara ọkpụkpụ - mgbu azụ,
  • Allergies - na - ekpuchi akpụkpọ ahụ na nchapu, urticaria.

Etu esi ewere isoprinosine?

Ntụziaka maka iji mbadamba ihe maka ndị okenye na ụmụaka:

- Ndị okenye dịkarịa ala 500 mg na ọ bụghị ihe karịrị 4 g kwa ụbọchị,

- A na-agbakọkwa usoro maka ụmụaka na-erubeghị afọ 12 site na usoro 50 mg kwa kilo nke ịdị arọ ahụ kwa ụbọchị.

- Maka ndị okenye na ụmụaka, a na-eme ka mmụba nke usoro ọgwụgwọ maka ụdị ọrịa ahụ siri ike maka ebumnuche ọgwụ. Otu ihe a metụtara oge nchịkwa, oge ọgwụgwọ.

Nkọwa nke ọgwụgwọ ọgwụgwọ

  • Treatmentgwọ ọgwụgwọ dị mma na-abawanye ma ọ bụrụ na ọgwụ malitere site na ụbọchị mbụ nke ọrịa.
  • Ọ dị mkpa ileba anya n'ihe gbasara uric acid n'ime mmamịrị na ọbara, ọkachasị ndị ọrịa nwere ọrịa hepatic,
  • Ndị na-akwọ ụgbọ ala na usoro ndị ọzọ chọrọ nlebara anya pụrụ iche kwesịrị ịmara na ọgwụ ahụ nwere ike imetụta ọrụ ha, na-akpata ọgbụgbọ na agụụ maka ụra. Nke a nwere ike imetụta nchekwa.

Mmekọrịta na ọgwụ ndị ọzọ

  • Nlekọta oge nke immunosuppressants na-ebelata mmetụta isoprinosine,
  • Ojiji allopurinol na diuretics dị iche iche, tinyere furosemide na ethaclates acid, na-ebute mmụba nke uric acid na ọbara,
  • Iji zidovudine ọnụ na-eme ka ogo zidovudine dị n'ọbara.

Ndepụta nke analogues nke mbadamba ihe eji emepụta Russia na nke mba ọzọ

Analogues dị ọnụ ala karịa IsoprinosineApteka.ru (ọnụ ahịa na rubles)Piluli.ru (ọnụ ahịa na rubles)
MoscowSPbMoscowSPb
Groprinosin (ụdị mbadamba)555571636565
Amixin (mbadamba)598598589535
Lavomax (taabụ.)540554533436
Arbidol (capsules)476490475425
Ergoferon (okpokoro)346359324293
Tilaxin (okpokoro)214222
Alpizarin (okpokoro)216225199171
Hyporamine (okpokoro)182159127

Amiksin - (onye nrụpụta Russia)

N'ụzọ dabara adaba na-anagide ọrịa nke herpetic, ịba ọcha n'anya A, B, C, flu na SARS. Amara ya nke ike ibuso otutu sclerosis, urogenital na chlamydia nke iku ume.

Mmetụta ọjọọ na usoro nri diges na-adakwasị. Na mgbakwunye, mmeghachi omume nfụkasị ga-ekwe omume.

Lavomax - (ụdị ụlọ)

Ọ dakọtara kpamkpam, na ihe mejupụtara ma na-arụ ọrụ na ngwaọrụ nke gara aga. Dị ka Amixin, a na-atụ aro maka ịlụ ọgụ megide ịba ọcha n'anya, herpes. Na mgbakwunye, ọ na-egbochi multiple sclerosis, influenza na SARS.

N’ụdị ihe ijuanya na-eme ọfụma, a na-agụpụkwa ihe nfụkasị ahụ, nsogbu nri, na mmetụta nke mgbu.

Ergoferon - (atụmatụ ndị Russia dị ọnụ ala)

Ọgwụ antiviral a ma ama nwere ọtụtụ ihe na-egosi. Ikike ya gụnyere ihe mgbochi na ịgwọ ọrịa influenza A, B, nnukwu ọrịa na-efe efe na-efe efe.

Ọ na - enyere aka imeri ọrịa herpesvirus. A na-ahụta Ergoferon site na ọgụ dị mma megide nnukwu ọrịa eriri afọ, nke nje dị iche iche kpasuru.

Na-egbochi ma gbochie meningitis, oyi baa, ụkwara nta.

Tilaxin - (Russia)

O nwere myiri na Amiksin na Lavomaks. Ọ na-agwọ nnukwu ọrịa akụkụ okuku ume na nje, influenza, ịba ọcha n'anya, herpes. Edere ya dịka ọgwụ mmezi maka encephalomyelitis, chlamydia, ụkwara ume ọkụ.

Mmetụta na-adịghị mma n'ahụ ahụ onye ọrịa bụ ọgba aghara na eriri afọ, akpata oyi na obere oge.

Alpizarin - (RF)

Ọ ọkachamara n'ọrịa akpụkpọ ahụ na akpụkpọ ahụ mucous nke ọrịa herpes kpatara. Na-eguzogide site na sarcoma's Kaposi, waatị, derraloses, gụnyere lichen.

Ọ ga-edo anya na ndepụta nke mmetụta ndị ọ na-enwe. Vomiting, imebi eriri afọ, migraine, ike ọgwụgwụ, akpụkpọ ahụ na-apụta.

Mkpebi banyere mkpụrụ ndụ ihe eji eme ọnụ ma dị ọnụ ala

N'ịtụlela ọgwụ nje, ọ bara uru ichikota na ọ nwere aha ọma na ahịa ọgwụ ụlọ. N'otu oge, ọnụahịa maka Isoprinosine dị elu ma nwee ike imetụta ọnọdụ ego nke ndị ọrịa.

N’ahịa ụlọ, ụlọ ọrụ ndị na-emepụta ọgwụ ebidola imepụta ọgwụ ọgwụ gbasara ọnụahịa dị ọnụ ala.

Tupu ịzụta nnọchi, ị ga-agarịrị dọkịta nke ọkachamara ọrịa na-efe efe, onye, ​​ebe ọ bụ na eburu ụzọ kpebie ọrịa ahụ, ga-ewepụta usoro ọgwụgwọ.

Analogs nke ọgwụ Fraxiparin

Calcium Nadroparin
Bipụta ndepụta analogues
Nalsroparin calcium (Nadroparin calcium) Anticoagulant na-edozi usoro maka nchịkwa subcutaneous

Ọ nwere mmetụta antithrombotic. Heparin dị ala dị ala nwetara site na ọkọlọtọ usoro nke depolymerization.

Na njikọta na antithrombin III, a na-egosipụta ya site na mmemme akpọrọ ihe megide XA na nke esighi ike megide ihe IIa.

Na-eme ka mmetụta antithrombin III na-emetụta ihe XA, nke na-eme ka mgbanwe nke prothrombin gaa na thrombin. Mgbochi nke ihe XA pụtara na nchịkọta nke 200 PIECES / mg, thrombin - 50 PIECES / mg. A na-akpọ ọrụ Anti-XA nke ọma karịa mmetụta ọ rụpụtara na APTT. Ọ nwere mmetụta dị ngwa ma na-adịgide adịgide. Egosiputara ihe omume n’otu nkeji nke European Pharmacopoeia (Ph. Eur.) IU-anti-Xa.

O nwere mgbochi mkpali na immunosuppressive (na-egbochi imekọ ihe ọnụ nke T- na lymphocytes), belata mbelata cholesterol na beta-lipoproteins n'ọbara ọbara. Ọ na - eme ka ọbara na - ekesa ọbara.

Mgbochi nsogbu nke thromboembolic (gụnyere ndị metụtara ịwa ahụ ọhụụ, oncology na orthopedics, na ndị ọrịa na-abụghị ịwa ahụ nwere nnukwu thromboembolism: nnukwu akụkụ okuku ume, ọrịa purulent-septic, ọrịa obi na-adịghị ala ala), mgbochi nke coagulation ọbara n'oge ịba ọcha.

Ọgwụ nke thrombosis na thromboembolism, angina na - ejighi ike na infarction myocardial na - enweghị ebili mmiri Q.

Ngwa na usoro onunu ogwu

Banye n'ime afọ dị n'okpuru afọ nke anụ ahụ, banye na ọkpụrụkpụ akpụkpọ ahụ (agịga ahụ dịgidere na akpụkpọ anụ ahụ). A na-edozikwa mpempe akwụkwọ ahụ n'oge ọrụ nchịkwa.

Mgbochi thromboembolism n'ịwa ahụ niile: 0.3 ml 1 oge kwa ụbọchị. A na-etinye 0.3 ml awa 2-4 tupu ịwa ahụ. Usoro ọgwụgwọ ya dịkarịa ala ụbọchị asaa.

Maka ebumnuche ọgwụgwọ: a na-ahụ maka ya ugboro abụọ n'ụbọchị maka ụbọchị iri na mkpụrụ 225 U / n'arọ (100 IU / n'arọ), nke kwekọrọ: 45-55 n'arọ - 0.4-0.5 ml, 55-70 n'arọ - 0,5-0.6 ml, 70 -80 n'arọ - 0.6-0.7 ml, 80-100 n'arọ - 0.8 ml, karịa 100 n'arọ - 0.9 ml.

N'ime ịwa ahụ orthopedic, a na-ahọrọ dose ahụ dabere na ahụ ọ bụla. A na-ahụ ya otu ugboro kwa ụbọchị, na usoro ndị a: na -arụ ogo ahụ erughị 50 n'arọ: 0.2 ml n'oge ime ya na n'ime ụbọchị 3 mgbe a wasịrị ya ahụ, 0.3 ml na oge ọrụ (malite ụbọchị 4).

Site na aru aru nke 51 rue 70 n'arọ: na oge ime ihe ma n’ime ubochi ato ka ogwusiri - 0.3 ml, na mgbe akpochapu (malite na ubochi ano) - 0.4 ml. Site na aru aru nke aru 71 rue 95 n'arọ: na mgbe akpochapu aru ma n’ime ubochi ato ka emechara ya - 0.

4 ml, na mgbe akarị (malite ụbọchị 4) - 0.6 ml.

Mgbe venography, a na-elekọta ya kwa awa iri na abụọ maka ụbọchị iri, ọnụọgụ ahụ dabere na ịdị arọ ahụ: yana oke nke 45 n'arọ - 0.4 ml, 55 n'arọ - 0,5 ml, 70 n'arọ - 0.6 ml, 80 n'arọ - 0.7 ml, 90 n'arọ - 0.8 ml, 100 n'arọ na ndị ọzọ - 0,9 ml.

Na ọgwụgwọ nke angina pectoris na-akwụghị chịm na infarction myocardial na-enweghị ebili mmiri Q, a na-ahụ 0.6 ml (5700 IU antiXa) ugboro abụọ n'ụbọchị.

Ngwongwo ogwu

Usoro nke ime ihe Calcium nadroparin bụ heparin dị obere agịga (LMWH) nke enwetara site na njupụta nke heparin.Ọ bụ glycosaminoglycan nke nwere ntakịrị molecula ruru ihe dị ka 4300 daltons.

Nadroparin gosipụtara ikike dị elu iji protein protein plasma nwere antithrombin III (AT III). Ngbenye a na - eduga n'ịgbazi ihe nke Xa. nke sitere na ike antithrombotic nwere nadroparin. Usoro ndị ọzọ na-enye mmetụta antithrombotic nke nadroparin.

gụnyere mmebe nke inhibido ihe anụ ahụ (TFPI), mmegharị nke fibrinogenesis site na mwepụta nke Plasminogen anụ ahụ na - eme ka mkpụrụ ndụ endothelial, na ịgbanwere rheology ọbara (ibelata viscosity ọbara na mmụba nke permeability nke platelet na granulocyte membranes).

Mlọ ọgwụ Ejiri Nadroparin ka ọ rụọ ọrụ dị elu megide ihe XA kpatara, ma e jiri ya tụnyere ọrụ megide ihe IIa. Ọ nwere ma ọgwụ antithrombotic dị nso ma dị ogologo oge.

N'iji ya na heparin na-adịghị arụ ọrụ, nadroparin nwere obere mmetụta na platelet na nchịkọta, yana enweghị obere nsogbu na hemostasis.

Na usoro onyonyo prophylactic, ọ naghị ebute mbelata nke ọma na ọkara akụkụ ọkara (APTT).

Site na usoro ọgwụgwọ n'oge arụ ọrụ kachasị, enwere ike ịgbatị APTT ruo uru 1.4 dị elu karịa ọkọlọtọ ahụ. Ogologo oge dị otú a na-egosipụta nsị antithrombotic mmetụta nke calcium nadroparin.

Mlọ ọgwụ A na-ekpebi ihe ndị dị na Pharmacokinetic na ntọala nke mgbanwe na ọrụ ihe mgbochi ọgwụ nke plasma.

Mgbe nchịkwa subcutaneous gasịrị, arụmọrụ anti-Xa kacha (C max) na-enweta mgbe elekere iri atọ na ise (T max) gachara.
Bioavailability Mgbe nchịkwa subcutaneous gasịrị, nadroparin na-agbakarị kpamkpam (ihe dịka 88%).

Site na nchịkwa intraven, a na-arụ ọrụ mgbochi kachasị Xa na erughị nkeji iri, ọkara ndụ (T½) bụ ihe dịka awa 2.

Metabolism metabolism na-aputa ihe tumadi na imeju (desulfation, depolymerization).

Ndụ ọkara ahụ mgbe nchịkwa subcutaneous dị ihe dị ka awa 3.5. Otú ọ dị, ọrụ anti-Xa na-adịgide ma ọ dịkarịa ala awa 18 mgbe a gbasasịrị nadroparin na oke nke 1900 anti-XA ME.

Otu nsogbu

Ndị okenye na-arịa ọrịa
N'ime ndị ọrịa agadi, n'ihi mbelata nke ọrụ akụrụ, iwepu nadroparin nwere ike belata. Ihe nwere ike itughari akuko gbasara ndi oria a choro ntule na ndozi onodu kwesiri ekwesi.

Ndị ọrịa nwere ọrụ gbasara akụrụngwa Na ọmụmụ gbasara ọgwụ gbasara ọgwụ pharmacookinetics nke nadroparin mgbe enyere ndị ọrịa nsogbu gbasara akwara gbasara ịdị iche iche, e guzobere mmekọrịta dị n'etiti mmachi nke nadroparin na nwepu nke creatinine.

Mgbe atụnyere ụkpụrụ nke enwetara na nke ndị ọrụ afọ ofufo siri ike, achọpụtara na AUC na ọkara ndụ ka agbagoro na 52-87%, na ikike idozi creatinine na 47-64% nke ụkpụrụ dị mma. Ọmụmụ ihe ahụ chọpụtara ọdịiche ndị mmadụ buru ibu.

N'ime ndị ọrịa nwere nnukwu akụrụ egwu, ọkara nke nadroparin nwere nchịkwa subcutaneous mụbara ruo awa 6.

Nsonaazụ nke ọmụmụ a gosipụtara na enwere ike ịhụ ntakịrị ihe nchịkọta nadroparin na ndị ọrịa nwere nnukwu akwara na-ada ada ma ọ bụ na-adịghị ala ala (njikwa nke creatinine dị ukwuu karịa ma ọ bụ ya ka Som / min na erughị 60 ml / min), ya mere, usoro Fraxiparin kwesịrị belata 25% na ndị ọrịa dị otú ahụ na-enweta Fraxiparin maka ọgwụgwọ nke thromboembolism, angina pectoris / myocardial infarction na - enweghị ebili mmiri A na - enyefe Fraxiparin na ndị ọrịa nwere nnukwu akụrụ siri ike, iji wee gwọ ọnọdụ ndị a. N'ime ndị ọrịa nwere obere akwara ezughi oke, na ojiji nke Fraxiparin maka mgbochi nke thromboembolism, nnabata nadroparin adịghị agafe nke ahụ na ndị ọrịa nwere ọrụ gbasara ọrụ nkịtị, na-ewere usoro ọgwụgwọ Fraxiparin. Ya mere, iwetulata Fraxiparin ewere maka ebumnuche profilactic na udi ndi ọrịa a achoghi ya. N'ime ndị ọrịa nwere nnukwu akwara na-anata prophylactic fraxiparin, mbelata dose nke 25% dị mkpa ma e jiri ya na usoro onyonye enyere ndị ọrịa nwere ikike idozi okike ya.

A na-ewebata heparin dị obere irighiri akwara na usoro akwara dialysis zuru oke iji gbochie coagulation ọbara na akaghị. Mdị ọgwụ Pharmacokinetic anaghị agbanwe agbanwe, ma ewezuga oke ịdoụbiga mmanya ókè, mgbe ụzọ ọgwụ ga - esi banye n'ọbara sistemụ nwere ike ibute mmụba nke ọrụ ihe metụtara mbipụta metụtara usoro ikpeazụ nke ọdịda akụrụngwa.

Analoo Fraxiparin

akụ m (jana)

Ndi odi nkpe ..

Mụ nwanyị, ọ nwere nnukwu ọdịiche dị n’etiti Clexane na Fraxipain? Akwụzi m Kleksan na onye ọkachamara n'ọrịa ụmụ nwanyị 0.4 (ọ bụghị ihe doro anya kpatara na ọkachamara n'ọrịa ụmụ nwanyị na-ahọpụta ya) '(nye ndị ọkachamara n'ọrịa ọbara na Tuesday 13) Amalitere m ikwu banyere ịgbanye 0.6.

Ternyaahụ agara m 0.4 ọzọ, mgbe ahụ ọ ga-efu m 0.6 ma ọ bụrụ na. Mụ nwanyị nke 816 rubles, i.e. maka iri na abuo, kwesiri ka akpọpu ya na mpaghara 10,000 rubles. Abụghị m nwanyị nke nde ego ma enweghị m ebe obibi akwụkwọ ọ bụla, n'agbanyeghị etu o si dị njọ, echere m na ọ nọghị na onye ọ bụla.

LCD na-enye ntinye nke fraxiparin

Mụ agbọghọ ndị na-abanyekwa analogues nke fraxiparin na clexane n'ime afọ ime? Ekwesịrị inye m ọgwụ ndị a na LCD, mana ha na-ekwu na ha adịghị, na ha chọrọ idepụta ụfọdụ analogues, enweghị m oge iji kpoo aha na Ntụziaka (ha enyebeghị ya).

Ha na-ekwu na ọ bụ otu ihe. Mana ọ bụrụ na nke ahụ dị, yabụ dọkịta (dọkịta anaghị ede ọgwụ maka LCD) ga-ebu ụzọ kwupụta ndepụta ọgwụ niile m nwere ike iji, o wee dee naanị Fraxiparin na clexane.

Analogs nwere ike ezigbo mmetụta…

OGWU ANYI N'AGBARA EGO

Fraxiparin, Clexane, Wessel Douai ntuziaka maka ojiji, ọnụ ahịa, analogues

Gụkwuo ... Olga (nne Vova)

Hemopaxan dị ka atụ nke Fraxiparin

Na LCD m, e nyere m ọgwụ maka Hemopaxan na-akwụghị ụgwọ, nke yiri ka ọ bụ analog nke Fraxiparin. Anyone nweela onye nụtụrụla ọgwụ a? N'ezie analog? Ha tụrụ aro ịnwale ya n'ihe egwu na ihe ọghọm gị.

Fraxiparin hụrụ m nkọ nkọ, kenyere m ọgwụ dibịa ya dị ka "ọ bụrụ na", iji gosi na oxygen na nwa ahụ na-agbapụta na-enweghị nsogbu… .. Achọrọ m ịnwale, mana n'ihi

Amaghị m ihe ọ bụla gbasara ọgwụ a - m kpebiri ịrịọ na nnọkọ…

Kalenda nke ime izu

Anyi ga - agwa gị ezigbo akụkọ banyere nne anyị ndị gabigara ihe a ma ọ bụ na - agafe ugbu a!

Fraxiparin na ụlọ ọrụ

Anaghị m ule ọ bụla pụrụ iche, otu ihe ahụ ka ọ dị, edere fraksiparin. Site na otu nyocha, ọnụ ọgụgụ platelet nwere ntakịrị ịrị elu. Agaraghị m ọkachamara n'ọrịa dimkpa na, na isi, ọ nweghị ụzọ ịga. Enwere ajụjụ ole na ole. Dọkịta na-ekwu “ga-enwerịrị” na ihe niile dị otu ahụ.

O nweghị ihe dị. Enweghị m ike ịgbanwe dọkịta.

1) tinye njedebe nke afọ ime? 2) kedu ihe ga - eme ma oburu na ichoghi igba otutu oge? Dịka ọmụmaatụ, ọ bụrụ na enweghị ọgwụ na ahịa ọgwụ ọ bụla 3) ọ bara uru ị were hemostasiogram? Ebee ka m ga - eso ya mgbe ahụ, ma ọ bụrụ nye ndị ọkachamara n'ihe banyere ọbara

M ga-ere Zibor 3500! Moscow Nkwa

Mụ nwanyị, ana m ere analog nke clexane na fraksiparin. Ọ bịarukwuo m nso, n'agbanyeghị na ọ siri ike ịchọta. Emere afọ ime niile !! Tsibor 3500 5 PC maka 1000 r. Kwadoro ruo mgbe 05.2016.

Azụtara m na mbubreyo August tupu ịmụrụ nwa 10 PC maka 3550 p. Enwere m ike inye corinfar ihe fọrọ nke nta ka ọ bụrụ ọnya ọnya mkpụrụ ya na mgbakwunye. Zibor rụchara ọrụ nke ọma, nke a bụ ihe m chọrọ onye ọ bụla! Moscow Nastya. Tẹ 8-926-93-67-560.

Bulite site na ọdụ ọdụ ụgbọ mmiri Yuzhnaya na ụbọchị ụka ...

Kwurịtanụ isiokwu gị n’obodo, nweta echiche nke ndị ọrụ na-arụ ọrụ nke Babloglog

Gaa n’obodo

Olga (nne Vovchik)

Ọbara site na imi mgbe ọ gbasịrị obere ka ọ dịrị ọbara

Ternyaahụ bụ nrịba ikpeazụ nke Gemapaksan, nke ndị dọkịta depụtara m maka "onye ọ bụla na-agba ọkụ", nke a bụ analog nke Fraksiparin, ihe ọ pụtara bụ na-ahụcha ọbara. Hemostasis n'ime injections dị mma, mana .... ụnyaahụ na taa, imi malitere na mberede.

Ọ bụghịkwa ole na ole, kamakwa isi iyi! Ma ọ kwụsịghị ruo ogologo oge. N’ezie, ụjọ tụrụ m.

Ejiri m n'ụzọ ziri ezi jikọta nke a na ingin Gemapaksan? Enwere olile anya na mgbe akagbuo injections (agaghị m eme taa) nkọcha a ga-akwụsị? Nke a emebeghi tupu .......

Gụkwuo… Mama m na Cuba

Aga m anabata dịka onyinye ma ọ bụ n’ọnọdụ mgbanwe ọgwụ! Moscow!

Girlsmụ nwanyị mara mma, m ga-arịọ maka onyinye ma ọ bụ ka mụ na mmadụ nwekọrịta, gịnị na-adịgide mgbe mkpali ahụ?! Anyị chọrọ menopur (ma ọ bụ ihe atụ ya), sụgharịa sirinji, cytrocide, orgalutran, na-eregharị! Ntali nke asaa (IVF), ọ dị mwute ikwu na anyị enweghị snowflakes, n'ihi na Mgbatị 1-3 na-adị ndụ oge niile, na-ebufe ihe niile, yabụ na ị ga-abanye n'ime usoro ahụ oge ọ bụla nke ọhụụ! Enwere ike ịgbanwe ihe, enwere m ike ịhụ ihe m nwere site na ọgwụ m iji kwado ime (Utrozhestan, Clexane, Fraxiparin!? Ọ bụrụ ...

Ana m enye ọgwụ nkwado a kagbuo

Ana m enye ọgwụ nkwado a kagbuo na protocol maka ego ọnụahịa nke Fraxiparin 0.3 1 pc. URGENTLY ruo 06.2015! Clexane 0.8 ml 2 pcs rue 01.2017 MARA Analog of clexane edema ọgwụ Anfibra (ọtụtụ) na ampoules nke 0.6 ml na 0.4 ml ka a ga-enye ndị nọ ya mkpa. nkwụghachi ụgwọ maka okporo ụzọ (akpọrọ ebe a site na Elena), ọ baghị uru, kagbuo ihe ọma!

fraxiparin ma obu aspirin kadio?!

Girlsmụ nwanyị, biko kọwaara m ya, ma ọ bụghị na isi m na-awa. Dọkịta m na-ekwusi ike na a ga-eji ọgwụ a na-eji fraxiparin injections (gbanye ya otu ugboro kwa ụbọchị 5) na ọgwụ aspirin-cardio ma ọ bụ ọgwụ analogues na mbadamba 100 mg n'abalị kwa ụbọchị.

Aghọtaghị m ihe kpatara nke a? Ọ dịghị akọwa n'ezie. Na-ekwu ihe dị ka ihe mejupụtara nke fraxiparin n'onwe ya agbanweela ma oge ụfọdụ ha na-eduga na nsonaazụ ọzọ, ya bụ, ha anaghị ehicha ọbara ahụ, kama ọ na-akpata mkpụkọ ọbara. Dị ka ihe dị ọhụrụ na ọgwụ.

Nke ahụ ọ̀ bụ eziokwu? M weputara nwa m nwoke…

Anfiber kama clexane, onye kporo ogwu ya?

Umu agbogho ndi no na clexane ma obu fraxiparin na ogwu yiri ya. M na-eji clexane oge niile, ma taa na ZhK, ha nyere analog nke Russia dị ọnụ ala karịa nke ọgwụ a, Anfibra, otu ihe na-arụ ọrụ, wdg. Onye chere ihu Echiche gị banyere ya, ma ọ bụ ikekwe mmadụ ịmịnye ya ọbara na onye ọzọ?

Nkwadebe mgbe emechara, Ukraine

Ree / zụta Ree utrozhestan, progina, kleksan, iberibe, Kiev Price300 UAH. 05/18/2017 09:27 Mpaghara: Kiev (Kiev) M ga-ere foduru nke ọgwụ: Utrozhestan 100mg dị irè ruo mgbe 08/08 - 300 UAH enwere 4 ngwugwu.

Proginova 2mg kwesịrị ekwesị ruo mgbe 2020, enwere ngwugwu 2 nke 200 UAH ọ bụla. Clexane 0.2ml dị irè ruo mgbe 09.2018, enwere sirinji 20 - 60 UAH maka otu sirinji. Fragmin 2500me (analog of clexane na fraxiparin) bara uru rue mgbe 09.

2018, enwere 18 shrishchov- 70 UAH maka injections sirinji nke Papaverine kwesịrị ...

Banyere ọgwụ oke ọnụ. Njem ọzọ na LCD,

Enwetara m ntụziaka site na Ngalaba maka ZhK na m chọrọ ọgwụ ọjọọ, agara m ZhK. Na Jenụwarị, ha depụtara analog nke Fraxiparin Anfibra, mana kama 0.6 ml achọrọ m, ha nyere m naanị 0.4.

Mgbe m bịara ichebe ma dọkịta ahụ hụrụ ọrịa hemostasis, ọ sịrị ozugbo 0.6 chọrọ. N’ọnwa Febụwarị, dịka onye isi kwuru. Alaka ahụ nyere iwu ampoules 30 nke 0.6 nke ọ bụla maka m. Dọkịta ahụ nyere ọgwụ maka ampoules 30. Mana n'eziokwu ọ tụgharịrị na ọ bụ naanị 20 ka enyere n'iwu.

Ha achọghịkwa inye. Go, ha na-ekwu, gụgharia Ntụziaka ahụ, agbagoro m n'okpukpu ụlọ nke 3rd ...

Innogep, fraksiparin, clexane - enwere ike ịgbanwe ibe gị?

Umuigbo! Ọzọ n’enwetaghị enyemaka gị na ahụmịhe gị n’ụzọ ọ bụla. Nyere ndụmọdụ! Enwere m thrombophilia na n'ihi nke a, aghaghị m ịnye ọgwụ ọnụ nke heparin dị ala dị ala n'oge afọ ime m. Ugbu a (izu 15) ejiri m ike Innogep 4500 - na Gris.

Mana ọ bụ oge ịlaghachi Russia, ọ nweghị ọgwụ a (echere m na n'ihi mmachi) yana analogue ya na sodium na-arụ ọrụ. Mana na Russia enwere Fraksiparin (agwara m ime mbụ m) na Kleksan. Ma enwere ọgwụ ndị ọzọ na-arụ ọrụ.

Otu n’ime unu n’oge ime…

My nkwado mgbe cryoprotection

Fraxiparin: ntuziaka, ihe ekwuru, analogues, egosi, contraindications, akporo na doses

Calcium Nadroparin * (Nadroparin calcium *) Anticoagulants

Aha onye nrụpụta Aha ọnụego ya
Fraxiparin 9500me / ml 0.3ml n10 sirinjiAspen Notre Dame de Bondeville / Nanolek, LLC2472.00
Fraxiparin 9500me / ml 0.4ml n10 syringe tubeAspen Notre Dame de Bondeville / Nanolek, LLC2922.00
Fraxiparin 9500me / ml 0.6ml n10 sirinjiAspen Notre Dame de Bondeville / Nanolek, LLC3779.00
Fraxiparin 9500me / ml 0.8ml n10 sirinjiAspen Notre Dame de Bondeville / Nanolek, LLC4992.00

020 (anticoagulant na-eme ihe ozugbo - heparin dị ala dị ala)

Ngwọta maka nchịkwa sc bụ transperent, ntakịrị opalescent, enweghị agba ma ọ bụ edo edo edo na agba.

Sirinji 1
kaltinarin nadroparin2850 IU Anti-Ha

Ndị na - ahụ maka ihe:: calcium hydroxide ma ọ bụ dilgọn hydrochloric acid (ruo pH 5.0-7.5), mmiri d / i (ihe ruru 0.3 ml).

0.3 ml - sirines otu (2) - blisters (1) - ngwugwu nke kaadiboodu; 0.3 ml - syringes single-2 (2) - blisters (5) - paali nke kaadiboodu.

Ngwọta maka nchịkwa sc bụ transperent, ntakịrị opalescent, enweghị agba ma ọ bụ edo edo edo na agba.

Sirinji 1
kaltinarin nadroparin3800 IU Anti-Ha

Ndị na-ahụ maka mbu: mmiri calcium hydroxide ma ọ bụ dilọn hydrochloric acid (ruo pH 5.0-7.5), mmiri d / i (ihe dị ka 0.4 ml).

0.4 ml - sirines otu (2) - blisters (1) - ngwugwu nke kaadiboodu 0.4 ml - syringes single (2) - blisters (5) - packs kaadiboodu.

Ngwọta maka nchịkwa sc bụ transperent, ntakịrị opalescent, enweghị agba ma ọ bụ edo edo edo na agba.

Sirinji 1
kaltinarin nadroparin5700 IU Anti-Ha

Ndị na - ahụ maka ihe:: calcium hydroxide ma ọ bụ dilgọn hydrochloric acid (ruo pH 5.0-7.5), mmiri d / i (ihe dị ka 0.6 ml).

0.6 ml - sirines otu (2) - blisters (1) - ngwugwu nke kaadiboodu; 0.6 ml - syringes single (2) - blisters (5) - ngwugwu nke kaadiboodu.

Ngwọta maka nchịkwa sc bụ transperent, ntakịrị opalescent, enweghị agba ma ọ bụ edo edo edo na agba.

Sirinji 1
kaltinarin nadroparinAnti-Ha 7600

Ndị na-ahụ maka mbu: mmiri calcium hydroxide ma ọ bụ dilọn hydrochloric acid (ruo pH 5.0-7.5), mmiri d / i (ihe dị ka 0.8 ml).

0.8 ml - sirines otu (2) - blisters (1) - ngwugwu nke kaadiboodu; 0.8 ml - syringes single-2 (2) - blisters (5) - ngwugwu nke kaadiboodu.

Ngwọta maka nchịkwa sc bụ transperent, ntakịrị opalescent, enweghị agba ma ọ bụ edo edo edo na agba.

Sirinji 1
kaltinarin nadroparin9500 IU Anti-Ha

Ndị na-ahụ maka mbu: mmiri calcium hydroxide ma ọ bụ dilọn hydrochloric acid (ruo pH 5.0-7.5), mmiri d / i (ihe ruru 1 ml).

1 ml - sirinji otu (2) - blisters (1) - ngwugwu nke kaadiboodu 1 ml - sirinji otu (2) - blisters (5) - ngwugwu nke kaadiboodu.

Fraxiparin analogues

NJIKWUTA banyere ọgwụ Fraxiparin

Omume ọgwụ
Calcium nadroparin (ihe na-arụ ọrụ nke Fraxiparin) bụ heparin dị ala nke nwere heparin sitere na heparin ọkọlọtọ site n'ọnọdụ depolymerization n'okpuru ọnọdụ pụrụ iche ọgwụ ahụ bụ ihe akpọrọ megide ihe kpatara ọbara ọbara ụkọ Xa na arụ ọrụ adịghị ike megide ihe Pa. A na-akpọ ọrụ Angi-Xa (i.e., antiplatelet / platelet adhesion / task) nke ọgwụ ahụ karịa nsonaazụ ya na mpempe platelet thrombocyte na-arụ ọrụ (ihe na-egosi ọnụego coagulation ọbara), nke na-eme ka mkpụrụ obi nadroparin dị ọcha na heparin na-enweghị usoro. Ya mere, ọgwụ ahụ • nwere ọgwụ antithrombotic (na-egbochi imepụta eriri ọbara), ma nwee ọsịsọ ma na-adịgide.

Ihe ngosi maka ojiji
A na-akwado iji ojiji nke Fraxiparin maka:

• mgbochi nke nsogbu ụbụrụ thromboembolic (ịkpụpụta mkpụkọ ọbara na akwara) mgbe usoro ịwa ahụ, ma n’ozuzu ya na n’ịwa ahụ, n’ebe ndị ọrịa na-anaghị awa ahụ nwere nnukwu nsogbu ibute ọrịa thromboembolic (nnukwu akụkụ iku ume na / ma ọ bụ ọrịa iku ume, nnukwu obi ọgụ), ndị ọrịa na-anara ọgwụgwọ na ngalaba nlekọta ahụike dị ukwuu, • mgbochi nke ịmịnye ọbara n'ọbara n'oge hemodialysis, • ọgwụgwọ nke nsogbu nke thromboembolic, • ọgwụgwọ nke ejighị n'aka. iliac angina pectoris na infarction myocardial na-enweghị ebugharị Q na ECG.

Ofzọ nke ngwa
Fraxiparin ezubere maka subcutaneous na

nchịkwa intraven. Ejila intxiusinal int Frameparin. Site na ntinye nke Fraxiparin, enweghi ike ịgwakọta ya na ọgwụ ndị ọzọ Mgbochi Mgbochi Ọrịa thromboembolic Nnukwu ịwa ahụ. Ọgwụ a na-atụ aro na mbụ bụ 0.3 ml nke Fraxiparin otu ugboro kwa ụbọchị maka subcutaneously maka opekata mpe asaa. N'ọnọdụ ọ bụla, mgbochi kwesịrị ịmalite n'oge oge ihe ize ndụ.

A na-etinye ọgwụ izizi nke 2 ruo 4 awa tupu ịwa ahụ. A na-etinye ọgwụ mbụ nke Fraxiparin awa iri na abụọ tupu awaa ya awa iri na abụọ mgbe ọ gbasịrị ya. A na-aga n'ihu iji ọgwụ ahụ maka ọ dịkarịa ala ụbọchị 10. N'ọnọdụ ọ bụla, mgbochi kwesịrị ịmalite n'oge oge ihe ize ndụ.

Ahapụ Gị Ikwu