Diabetalong, Russian na analogues nke ọgwụ na ọnụahịa na nyocha

Diabetalong bụ ọgwụ nwere usoro eji eme ya dịka akụkụ nke monotherapy ma ọ bụ usoro ọgwụgwọ ngwakọta maka ụdị shuga 2. Edebere mbadamba diabetalong na enweghị mmetụta dị ukwuu nke mgbazi nri yana ọrụ anụ ahụ nke onye ọrịa, kwekọrọ na afọ ya na njikwa ahụ.

Ekwesịrị ijikọ ya na ọgwụ ahụ yana nri ọgwụgwọ (tebụl No. 9) - nke a dị mkpa iji gbochie mwakpo hypoglycemic ma bulie arụmọrụ nke ọgwụgwọ.

Otu akụkụ pụrụ iche nke ọgwụ ahụ bụ ịhapụ ọgwụ ndị na-arụ ọrụ ogologo oge, nke na-enye ohere belata ọgwụ kwa ụbọchị ma hụ na mbelata ogo glucose na nkeji na - ekesa ọbara.

Ngwa

"Diabetalong" na-ezo aka na otu ọgwụ nwere mmetụta hypoglycemic, nke a na-eji dịka ọgwụgwọ bụ isi maka ọrịa mellitus na-abụghị insulin. Ihe na-arụ ọrụ nke mbadamba nkume ndị ahụ bụ gliclazide.

Nke a bụ ọgwụ nwere ọrụ nhọrọ dị elu, yana bioavailability yana ịba ụba na iguzogide gburugburu ebe obibi dị iche iche.

Mmetụta ọgwụgwọ nke ọgwụ ahụ sitere na Njirimara nke gliclazide, n'etiti ndị:

mụbara insulin n'ahụ nke ha, nke na-ebelata oke ịba ahụ homonụ ịbara n’ime ọbara.
mkpali nke mkpụrụ ndụ beta (mkpụrụ ndụ na - eme ka akwara ndị dị n’akpịrị ikiri ma na - achọpụta akụrụngwa nke endocrine),
normalization nke carbohydrate metabolism (karịsịa na ndị ọrịa na oke ibu nke ọrịa mamịrị ụdị 2, 3 ma ọ bụ 4 ogo),
ihe mgbochi nke platelet agakọ (nsogbu) yana mgbochi nke thrombocytopenia, thromboembolism na thrombosis.

E gosiputara na Diabetalong nwere ọrụ mgbochi ma belata ihe egwu nke ibute ọrịa na - egbu egbu site na obi, arịa ọbara, akwara nri na ụbụrụ.

Mkpụrụ ọgwụ dị ike nwere ọgwụ nwere ogologo oge, a na-enwetakwa itinye uche ya kachasị n'ime awa 4-6.

A na-echekwa nsonaazụ nke ọgwụ ahụ ruo awa 10-12, ọkara ndụ dịkwa site na awa isii ruo awa iri na abụọ (ọ dabere na sistemụ arụ ọrụ na-arụ ọrụ).

Ngosipụta maka ị ofụ ọgwụ ahụ bụ ụdị ọrịa shuga mellitus nke 2 - ụdị nnwere onwe nke onye ọrịa ahụ nwere ọrịa hyperglycemia na-adịghị ala ala (mmụba na glucose ọbara) yana mmetụta anụ ahụ na insulin.

Mpempe mwepụta

"Diabetalong" dị n'otu ụdị usoro onunu ogwu - nke wepụtara ogologo oge ma ọ bụ nke mbadamba ihe-ọhụụ gbanwere. Lọ ọrụ na-emepụta ọgwụ na-emepụta ọgwụ abụọ:

30 mg (ngwungwu 30) - akwadoro maka usoro ọgwụgwọ mbụ,
60 mg (mkpọ 60 iberibe).

Onye nrụpụta na-eji ihe mgbakwunye dị ka ihe inyeaka, dịka ọmụmaatụ, calcium stearate, silicon dioxide na talc.

Enwere ike ịnabata mmachi ọgwụ ahụ site na lactose (n'ụdị nke monohydrate) - ụmụ irighiri mmiri ara ehi nwere ụmụ irighiri mmiri.

Ndị ọrịa nwere ọrịa lactase ma ọ bụ enwetara lactase nwere ike ịrịa ọrịa diski, ya mere, na usoro a, analogues ma ọ bụ dochie ya nwere ihe ndị yiri ya na-enweghị shuga mmiri ara ehi kwesịrị ịhọrọ.

Mbadamba ụrọ ahụ na-acha ọcha ma dị larịị n'ụdị nke sịlịnda.

N'ọnọdụ ụfọdụ, ọgwụ ahụ nwere ike ịmịcha mkpụrụ - a na-akọwara ihe ịtụnanya a site na nkesa ezighi ezi nke talcum base na anaghị emetụta Njirimara ọgwụ nke ọgwụ.

Ntụziaka maka ojiji

Ntuziaka maka iji "Diabetalong" na-atụ aro ị theụ ọgwụ 1 ugboro 2 kwa ụbọchị (dabere na usoro ọgwụgwọ enyere).

Ọ bụrụ na ị dailyụ ọgwụ kwa ụbọchị bụ mbadamba 1-2, a ga-emerịrị ya n'otu ụtụtụ.

N'agbanyeghị eziokwu ahụ bụ na nkọwapụta ahụ na-enye ohere ịre mbadamba n'etiti nri, ịdị irè nke ọgwụgwọ ahụ ga-adị elu ma ọ bụrụ na ị were "Diabetalong" nkeji 10-20 tupu eri.

Ọ bụrụ na onye ọrịa echefula ị theụ ọgwụ ahụ, ọ dị mkpa ịmaliteghachi ọgwụgwọ site na ngwa ọzọ enyere n'aka nke usoro ojiji na usoro usoro ọgwụ usoro ahụ siri arụ ọrụ.

Etinyela ogwu ahụ (dịka ọmụmaatụ, ịnweghị ike ịillsụ ọgwụ ụtụtụ na mgbede), n'ihi na nke a nwere ike ibute mwakpo hypoglycemia na mmepe nke akpịrị, ọkachasị ndị mmadụ karịa afọ 65 na ndị ọrịa nọ n'ihe ize ndụ.

Ihe ngbanwe

Tupu ị drugsụ ọgwụ hypoglycemic ọ bụla, ị ga-agakwuru dọkịta, ma na-emegide usoro ọgwụgwọ, ọ dị mkpa iji chịkwaa ọkwa shuga na arụ ọrụ nke sistem.

Amachibidoro ị drugsụ ọgwụ ọjọọ na otu a maka ụdị shuga 1, ebe nke a nwere ike ibute ịba ụba insulin n'ime anụ ahụ.

A na - egbochi ngwaahịa ndị Glyclazide n'ime ụmụ nwanyị dị ime na ndị nne na - enye nwa ara, n'ihi na ha nwere ike ibute ọrịa endocrine na ọrịa obi nke nwa n’afọ na n’afọ.

Ihe mgbochi ozo maka idebanye Diabetalong gunyere:

Ọrịa dị ukwuu nke akụrụ na umeji, na-eduga n'ịrụ ọrụ akụkụ zuru oke ma ọ bụ akụkụ ahụ.
nnukwu ọnọdụ esonyere mebiri nke carbohydrate metabolism,
mmezi nke mmeghachi omume nke ekweghị n'ihe ma ọ bụ mmetọ ahụ nye ihe ndị sitere na otu nke esi na usoro sulfonlurea ma ọ bụ sulfonamides,
ọrịa shuga na ọnọdụ ndị bu ya ụzọ,
ụkọ nke enzymes na-emebi shuga mmiri ara ehi (n'ihi ọnụnọ nke lactose na ihe mejupụtara).

A na-ezube Diabetalong naanị maka ịgwọ ndị ọrịa okenye.

Maka ndị gbara afọ 65, ọgwụ ọgwụ ahụ ka enwere ike ịkọwa ya naanị ka ọ na-enyocha kwa mmiri ọgwụ na mmamịrị biochemical mgbe niile. Mgbe ị na-ede akwụkwọ, ekwesịrị ịtụle usoro nke ọgwụ ndị a na-eji mee ihe. Amachibidoro ị gụ gliclazide na ọgwụ antifungal systemic nke dabere na miconazole, yana Danazol na Phenylbutazone.

Ọ dị mkpa ịmalite iji ọgwụgwọ dị ala nke 30 mg (mbadamba ihe ntọhapụ nke gbanwere). N'otu usoro onunu ogwu a, a na-atụ aro ka ndị nọ n'ihe ize ndụ maka mmepe nke ọnọdụ hypoglycemic. Ihe ndị nwere ike ibute gụnyere:

erighị ihe na-edozi ahụ na mineral na vitamin ezughị ezu na oke nri nwere nnukwu carbohydrates na shuga dị mfe.
agadi (karịrị 65)
enweghị na akụkọ banyere ọrịa nke iji ọgwụgwọ eji ọgwụ na-ebelata glucose ọbara,
ọgba aghara na arụ ọrụ grenia adrenal na pituitary gland,
ezughi oke nke homonụ thyroid nke thyroid gland,
carotid arteriosclerosis,
ọrịa obi obi siri ike (gụnyere ọrịa obi na-arịa ọrịa obi 3 na 4).

Ọgwụ a na usoro onunu ogwu nke 30 mg ka a na-ewere otu ugboro n’ụtụtụ n'ụtụtụ tupu ma ọ bụ n'oge nri ụtụtụ.

Maka ndị ọrịa ndị ọzọ, a na-agbakọọ usoro onyonye ahụ n'otu n'otu na-ebido ogo nke ọrịa, afọ onye ọrịa, shuga ọbara yana ihe ndị ọzọ na-egosi nyocha ụlọ nyocha nke mmamịrị na ọbara.

Thebọchị nke ọgwụ ahụ agaghị agafe 120 mg (mbadamba 2 nke 60 mg ma ọ bụ mbadamba 4 nke 30 mg).

Nsonaazụ

Mmetụta akụkụ ndị metụtara ya na Diabetalong bụ isi ọwụwa, uto na-adịghị mma, ụdị ọrịa hemolytic, na mmeghachi omume nfụkasị ụdị ahụ. N'adịghị ka ọ na-adịkarị, enwere akụkọ banyere nsogbu ndị ọzọ, nke gụnyere:

anya ntughari
Ọrịa nkwarụ
na-ama jijiji n’ahụ
mara nghọta nghọta,
ike iku ume na nsogbu na eloda nri,
yellowing nke anụ ahụ na mucous membranes nke anya sclera (ịba ọcha n'anya nke cholestatic ụdị),
mgbanyụ ihu anya,
mmụba n'ọbara.

N'ọnọdụ ụfọdụ, ị theụ ọgwụ "Diabetalong" nwere ike ịkpasu mmebi iwu na imeju, na-eyi ndụ nke onye ọrịa ahụ egwu. Ọgwụ nwekwara ike imetụta ọrụ nke hematopoiesis nke ụmị ọkpụkpụ, ya mere, ekwesịrị ịdaba ya na nlezianya nke onye ọkachamara, yana nri nri na ahụ ike zuru ezu.

A na-ahụta ọnụahịa nke "Diabetalong" dị oke ọnụ maka ụdị ndị ọrịa niile, ebe ọgwụ a na-akwụ ụgwọ na-ezo aka na ọnụahịa ọnụahịa dị ala. Ọnụ ego maka otu mbadamba mbadamba 60 bụ 120 rubles.

Enwere ike ịchọ ọgwụ analogues maka mmeghachi omume nfụkasị ma ọ bụ anabataghị akụkụ nke ọgwụ ahụ. Iji chịkwaa shuga shuga, dọkịta ahụ nwere ike ịkọwa ego site na otu nke usoro ọgwụgwọ sulfonylurea ma ọ bụ ọgwụ hypoglycemic ndị ọzọ nwere ụdị ọgwụgwọ ahụ.

"Ọrịa mamịrị" (290-320 rubles). Analogue nke “Diabetalong” nwere otu ihe eji arụ ọrụ. A na-ahụ ọgwụ ahụ ka ọ dị irè karị n'ihi mmalite ngwa ngwa nke ọgwụgwọ ọgwụgwọ - a na-enweta mkpokọta gliclazide kachasị na plasma ọbara n'ime awa 2-5.
"Gliclazide" (100-120 rubles). Nkwadebe hypoglycemic n'ụdị ntụ ntụ, analogue nke aha Diabetalong.
"Glucophage ogologo" (170-210 rubles). Ọgwụ ogologo oge, nke gụnyere metformin. Enwere ike iji ya dị ka ọgwụ bụ ọgwụ ma jikọta ya na insulin na ọgwụ ndị ọzọ iji belata shuga.

Ọ gaghị ekwe omume ịkagbu ọgwụ na hypoglycemic Njirimara nke aka ha, ebe ọ bụ na ha chọrọ iwepu nwayọ nwayọ site na ibelata usoro ịchekwa otu na ilele ọbara na mmamịrị mgbe niile. Ọgwụ ọ bụla n’ime ndị otu a nwere ike ịhọpụta ma nyekwa ya ọgwụ ọkachamara.

Dodoụbiga ya ókè

Ọ bụrụ na ị gafere ihe a tụrụ aro na mmalite nke akara nke hypoglycemic ọgụ, ị ga-emerịrị ọgwụ glucose (40% - 40-80 ml), wee were shuga gụrụ 5-10% gulite mkpali. Site na mgbaàmà dị nro, ị nwere ike iwelite ọkwa shuga ngwa ngwa na ngwaahịa ọ bụla nwere protein ma ọ bụ carbohydrates dị mfe.

Nyocha banyere ọgwụ maka ndị ọrịa mamịrị “Diabetalong” kacha mma.

Onye ọrụ Venera87 si n'obodo Kursk na nyocha http://otzovik.com/review_3106314.html kwuru na ngwa ọrụ ahụ nyeere ndị ikwu ya merela agadi aka ịchịkwa ọkwa shuga ha. Edere ọgwụ a na usoro onunu ogwu nke 30 mg otu ugboro kwa ụbọchị wee were ọgwụ ahụ ka dọkịta nyere ya iwu. O nweghi mmetụta ọ bụla dị n'akụkụ ahụghị n'oge ọgwụgwọ.

Vitaly Koval na-ekwukwa okwu ọma banyere ọgwụ ahụ ma kwuo na mbadamba ụta ahụ nyeere nne nne ya aka ịnagide ị ofụ shuga mgbe niile (https://health.mail.ru/drug/diabetalong/).

Mana Ivan, na ntụle, na-ekwu na ọgwụ ahụ adabaghị na nna ya, ma megide usoro ndabere nke ọgwụgwọ ahụ, onye ọrịa malitere inwe ihe mgbu dị ukwuu na mpaghara apịtị, n'ihi nke a ga-akwụsị ọgwụgwọ ahụ ụbọchị iri mgbe mmalite nke mbadamba (http: //www.imho24 .ru / nkwanye / 57004 / # review77231).

"Diabetalong" - ọgwụ nke dọkịta kwesiri inye ya naanị onye nwere ọgụgụ mmadụ na-agbakọ etu o si a andụ na usoro. Ọ bụrụ na ọgwụ ahụ adabaghị na ọrịa a kapịrị ọnụ, ị ga-agakwuru dọkịta wee họrọ ọgwụ hypoglycemic kwesịrị ekwesị.

Chekwaa ma ọ bụ kesaa:

Diabetalong na Moscow

Oral hypoglycemic ọgwụ, a na-enweta sulfonylurea nke ọgbọ nke abụọ.

Ọ na - akpali umeji insulin site na pancreas, na - agbada ọkwa nke glucose n'ọbara, na - eme ka mmetụta glucose dịkwuo elu ma na - eme ka ọ nwee mmetụta nke uru ahụ dị na insulin. Mgbe afọ 2 ọgwụgwọ gasịrị, ọtụtụ ndị ọrịa anaghị azụ ọgwụ ahụ (mmụba nke ọkwa insprandial insulin na nzuzo nke C-peptides na-aga n'ihu).

Na-ebelata oge dị n'etiti oge iri nri rue mmalite insulin insulin.

Ọ na - eweghachi mmiri ọgwụ insulin n'oge mbụ maka nzaghachi glucose (n'adịghị ka ihe ndị ọzọ sitere na sulfonylurea, nke nwere mmetụta tumadi n'oge ọkwa nke abụọ nke nzuzo).

Ọ na - emekwa ka usoro nke abụọ nke insulin na - ebuwanye ibu. Na-ebelata ọnụ ọgụgụ kachasị elu nke hyperglycemia mgbe ị risịrị nri (belata postprandial hyperglycemia).

Glyclazide na - eme ka anụ ahụ dị n ’insulin dịkwuo ala mara mma (ya bụ, nwere mmetụta extrapancreatic). Na akwara anụ ahụ, mmetụta insulin na -akpali glucose, n'ihi mmetụta anụ ahụ nke insulin na-abawanye ụba (ruru + 35%), ebe ọ bụ na glycazide na-akpali ọrụ nke muscle glycogen synthetase.

Na -ebelata usoro glucose na imeju, na -eme ka ebumnuche glucose ọnụ na-ebu ọnụ.

Na mgbakwunye na emetụta metabolism metabolism, gliclazide na-eme ka microcirculation dịkwuo mma.

Ọgwụ ahụ na-ebelata ihe ize ndụ nke thrombosis nke obere arịa, na-emetụta usoro abụọ nwere ike itinye aka na mmepe nke nsogbu na ọrịa shuga mellitus: ịhapụ akụkụ nke platelet na nrapado na mbelata ihe ndị na-eme ka platelet rụọ ọrụ (beta-thromboglobulin, thromboxane B2), yana mweghachi nke fibrinolytic vaskụla endothelial ọrụ na ụba ọrụ nke plasminogen anụ ahụ.

Glyclazide nwere ihe ndị na-egbochi antioxidant: ọ na-ebelata ọkwa nke peroxides lipid na plasma, na-abawanye ọrụ nke sel ọbara ọbara superoxide dismutase.

N'ihi ogo nke usoro onunu ogwu, usoro ubochi nke Diabetalong® 30 mg mbadamba ọgwụ na-enye nnabata ọgwụgwọ gliclazide dị irè na plasma ọbara ruo awa 24.

Mgbe nchịkwa ọnụ gachara, a na-etinye gliclazide kpamkpam na ngụgụ nri. Iri nri anaghị emetụta mmịpụta.

Ntinye uche nke ihe aru oru n’ime plasma obara ji nke nta nke nta mee, rute oke ma rute plateau rue elekere isii tupu i takingụọ ọgwụ. Onweghi ike n’otu n’otu di ala.

Mmekọrịta dị n'etiti dose na itinye uche nke ọgwụ na plasma ọbara bụ ihe kwụ chịm n'oge.

Nkesa na metabolism

Njikọ protein protein Plasma bụ ihe dịka 95%.

Ọ bụ metabolized na imeju na-abụkarị site na akụrụ. Ọ dịghị metabolites nọ n'ọrụ na plasma.

Cụpụ akụrụ site na akụrụ na-emekarị n'ụdị metabolites, ihe na-erughị 1% nke ọgwụ a apụbeghị.

T1 / 2 bụ ihe dịka awa iri na isii (awa iri na abụọ ruo iri abụọ).

Pharmacokinetics n'ihe gbasara ọrịa

N'ime ndị agadi, enweghị mgbanwe pụtara ìhè dị na pọọmọnkinetic ọgwụ.

- elldị ọrịa shuga abụọ nke ọrịa mellitus na usoro ọgwụgwọ nri na nri na mmega ahụ ezughi oke.

Emere ọgwụ a naanị maka ọgwụgwọ. nke ndi okenye.

30 mg mbadamba mbadamba Diabetalong® a na-ewere ọnụ ya otu oge / ụbọchị mgbe nri ụtụtụ.

Maka ndị ọrịa na-anatabeghị mbụ ọgwụgwọ (gụnyere maka mmadụ karịrị 65), usoro mbu bu 30 mg. Mgbe ahinyere dose ahụ n’otu n’otu rue mgbe ikewapụtara ọgwụgwọ ọgwụgwọ chọrọ.

A ga-eme nhọrọ nhọrọ ya dabere na ogo nke glucose dị n'ọbara mgbe mmalite ọgwụgwọ. Enwere ike ịgbanwe mgbanwe ọ bụla na - esote izu ma ọ dịkarịa ala izu abụọ.

Theụ ọgwụ kwa ụbọchị nwere ike ịdị iche site na mg mg 30 (1 tab.) Ruo 90-120 mg (3-4 tab.). Dosebọchị kwa ụbọchị ekwesịghị ịkarị 120 mg (4 mbadamba).

Diabetalong® nwere ike dochie mbadamba gliclazide mbido (80 mg) na mbadamba 1 ruo 4 / ụbọchị.

Ọ bụrụ n’otu ọgwụ ị oneụ otu ọgwụ ma ọ bụ karịa ga-efu gị, ịnweghị ike ị aụ ọgwụ dị elu na usoro ọzọ (na-esote ụbọchị).

Mgbe dochie ọgwụ hypoglycemic ọzọ na mbadamba Diabetalong® 30 mg, ọ nweghị oge mgbanwe. Must ga-ebu ụzọ kwụsị ị theụ ọgwụ kwa ụbọchị na naanị ụbọchị na-esote ịmalite ị startụ ọgwụ a.

Ọ bụrụ na onye ọrịa ahụ anatala ọgwụgwọ na sulfonylureas na ọkara ndụ ogologo, mgbe ahụ nlezianya nlezianya (nyochaa nke glucose ọbara) maka izu 1-2 dị mkpa iji zere hypoglycemia n'ihi nsonaazụ nsonaazụ nke usoro ọgwụgwọ gara aga.

Enwere ike iji Diabetalong® jikọta ya na biguanides, alfa glucosidase inhibitors ma ọ bụ insulin.

Ọrịa nwere nsogbu gbasara akụrụ na-ada ada ruo obere Edere ọgwụ ahụ n'otu usoro ogwu ahụ yana ndị ọrịa nwere ọrụ ezumike nkịtị. Na nnukwu nsogbu gbasara akwara Diabetalong® bụ contraindicated.

N'ime ndị ọrịa n'ihe ize ndụ nke ịmalite hypoglycemia (nri na-ezughị ezu ma ọ bụ nke na-adịghị edozi ahụ, nkwarụ endocrine na-arịa ma ọ bụ na-adịghị mma - pituitary na adrenal insufficiency, hypothyroidism, kagbuo glucocorticosteroids mgbe ogologo oge na / ma ọ bụ nchịkwa dị elu, ọrịa siri ike nke usoro obi. ajọ ọrịa obi, akwara carotid arteriosclerosis, atherosclerosis /) na-atụ aro ka iji ntakịrị opekata mpe (30 mg 1 oge / ụbọchị) nke ọgwụ Diabetalong®.

Hypoglycemia (nke megidere usoro usoro onunu ogwu na nri ezughi oke): isi ọwụwa, ike ọgwụgwụ, agụụ, ịsụsọ, adịghị ike siri ike, palpitations, arrhythmia, ọbara mgbali elu, iro ụra, ehighị ụra nke ọma, oke iwe, nchekasị, mgbakasị ahụ, ịta ahụhụ, enweghị ike itinye uche ma megharịa oge, ịda mbà n'obi, ọhụhụ ọhụhụ, aphasia. , ujo, paresis, nsogbu uche, nkụda mmụọ, mmetụta nke enweghị enyemaka, ọnwụ nke njide onwe onye, enweghị nchekasị, ihe ngbu, iku ume, bradycardia, ọnwụ nke mmụọ.

Site na nri digestive: ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, mgbu nke afọ, afọ ntachi (ogo ihe mgbaàmà ndị a na-ebelata mgbe ewere ya na nri), adịkarịghị - ọrụ imeju na - arụ ọrụ (ịba ọcha n'anya, ịba ụba ọrụ nke ịba ọcha n'anya, alkaline phosphatase, cholestatic jaundice - chọrọ iwepụ ọgwụ).

Site na akụkụ ahụ dị na hemopoietic: mgbochi nke ụmị ọkpụkpụ (anaemia, thrombocytopenia, leukopenia, granulocytopenia).

Mmeghachi omume nfụkasị ahụ: pruritus, urticaria, ọnya akpụkpọ, gụnyere maculopapular na okwu ojoo), erythema.

Ndị ọzọ: mmebi anya.

Nsonaazụ ndị ọzọ na-emetụtakarị nke sulfonylureas: erythropenia, agranulocytosis, hemolytic anaemia, pancytopenia, vasculitis nfụkasị, ọrịa imeju na-egbu ndụ.

Ihe ngbanwe

- ụdị shuga 1

- mamịrị ketoacidosis, ọrịa mamịrị, ụkwara ume ọkụ,

Na oke gbasara akụrụ na / ma ọ bụ imeju akwara,

- afọ ruo afọ 18

- oge ị breastụ nwa (na-enye nwa ara),

- ihe ọmụmụ nke lactose anabataghị, ụkọ lactase ma ọ bụ ọrịa glucose-galactose malabsorption,

- Hypersensitivity na gliclazide ma ọ bụ ihe ọ bụla nke ọgwụ ọgwụ, gaa n'ụkpụrụ ndị ọzọ nke sulfonylurea, na sulfonamides.

A naghị akwado ya ka ị useụ ọgwụ ahụ n'otu oge yana yana phenylbutazone ma ọ bụ danazole.

Na ịkpachara anya: nká, nsogbu na - anaghị edozi ahụ, ọrịa siri ike nke usoro akwara obi (gụnyere ọrịa obi na akwara, atherosclerosis), hypothyroidism, adrenal or pituitary insufficiency, hypopituitarism, renal na / ma ọ bụ imeju, ogologo oge na corticosteroids, ahoụrụma, ezughi oke. dehydrogenase glucose-6-phosphate.

Ime na lactation

Enweghị ahụmịhe na gliclazide n'oge afọ ime. Ihe omuma banyere ojiji nke ihe ndi ozo nke sulfonylurea n’oge di ime.

N'ime ihe omumu banyere umu anumanu, achoputala ihe omuma di nke gliclazide.

Iji belata ihe egwu nke ọrịa metụtara ọrịa metụtara ọrịa, ọ dị mkpa ijikwa ezigbo (ọgwụgwọ kwesịrị ekwesị) nke ọrịa shuga mellitus.

Anaghị eji ọgwụ hypoglycemic ọgwụ n'oge ime. Ọgwụ ịhọrọ maka ịgwọ ọrịa shuga n'ime ụmụ nwanyị dị ime bụ insulin. A na-atụ aro ka iji ọgwụ inspoglycemic nke na-aralụ ọgwụ jiri ọgwụ insulin dochie ya ma n'oge ime atụgharịrị, ma ọ bụrụ na ime mere mgbe ị na-a theụ ọgwụ ahụ.

N'iburu n'uche enweghị data na ị gụ gliclazide na mmiri ara ara yana ihe ọghọm nke ịmalite hypoglycemia nke afọ, a na-enye ụmụ ara ara n'oge ọgwụ.

Jiri na umuaka

Contraindicated n'ime ụmụaka na-erubeghị afọ 18.

Ọrịa hypoglycemia, nsogbu mmachi, hypoglycemic coma.

Ọgwụgwọ: ọ bụrụ na onye ọrịa maara, were shuga n'ime.

Ikekwe mmepe nke ọnọdụ hypoglycemic siri ike, tinyere coma, nkwarụ ma ọ bụ nsogbu akwara ndị ọzọ. Ọ bụrụ na ụdị mgbaàmà ndị ahụ apụta, nlekọta ahụike mberede na ụlọ ọgwụ ozugbo ọ dị mkpa.

Ọ bụrụ na enyo enyo na hypoglycemic coma na-enyo enyo ma ọ bụrụ nchoputa, 50 ml nke ihe 40% dextrose (glucose) na-abanye n'ime onye ọrịa ngwa ngwa. Mgbe ahụ, a na-edozi ngwakọta dextrose 5% (glucose) 5 n'ime oge iji mee ka ọkwa glucose dị n'ọbara chọrọ.

Mgbe ọ nwetasịrị, ọ dị mkpa inye onye ọrịa ahụ nri nwere nnukwu carbohydrates na-adị ngwa ngwa (iji zere ịmalite ịmalite hypoglycemia).

Ekwesịrị iji nlezianya nyochaa ọkwa glucose ọbara na nyochaa onye ọrịa ahụ ma ọ dịkarịa ala awa 48 na-esote.

Mgbe oge a gasị, dabere n'ọnọdụ onye ọrịa, dibịa na-aga na-ekpebi mkpa ọ dị inyochakwu ya.

Nchọpụta adịghị arụ ọrụ n'ihi nkwupụta akpọrọ nke gliclazide na protein protein.

Glyclazide na-akwalite nsonaazụ anticoagulants (warfarin); enwere ike ịchọ ndozi nke ọgwụ ahụ anticoagulant.

Miconazole (ya na usoro nchịkwa na mgbe ị na-eji gel na mucosa oral) na-eme ka mmetụta hypoglycemic nke ọgwụ ahụ dị elu (hypoglycemia nwere ike ịmalite ruo na coma).

Phenylbutazone (usoro nchịkwa) na-eme ka mmetụta hypoglycemic nke ọgwụ ahụ pụta (na-apụ n'ihi protein nke plasma na / ma ọ bụ na-akwụsịlata ahụ), njikwa glucose ọbara na mmezi nke glyclazide dị mkpa, ma n'oge nchịkwa phenylbutazone na mgbe ọpụpụ ya.

Ọgwụ ethanol nwere ọgwụ ethanol na-akwalite hypoglycemia, na-egbochi mmeghachi ụgwọ nkwụghachi ụgwọ, nwere ike inye aka na mmepe nke hypoglycemic coma.

Mgbe ewere ọgwụ ọgwụ hypoglycemic ndị ọzọ (insulin, acarbose, biguanides), beta-blockers, fluconazole, AC inhibitors (captopril, enalapril), ndị na-anabata ọgwụ mgbochi H2 (cimetidine), MAO inhibitors, hypoglycemic na sulfanilamides na akara ihe egwu nke hypoglycemia.

N'iji ihe eji eme ihe na iji Danazol, choputara ihe oria mamiri. Ọ dị mkpa ịchịkwa ọkwa nke glucose ọbara ma mezie ọnụọgụ nke gliclazide, ma n'oge nchịkwa danazol na mgbe ọpụpụ ya.

Chlorpromazine na ọnụọgụ dị elu (karịa 100 mg / ụbọchị) na-abawanye ọdịnaya glucose na ọbara, na-ebelata ihe nzuzo nke insulin. Ọ dị mkpa ijikwa glucose ọbara ma dozie dose nke gliclazide, n'oge nlekọta nke chlorpromazine na mgbe ọpụpụ ya.

GCS (usoro, intraarticular, mpụga, nchịkwa rectal) na-abawanye glucose ọbara na mmepe nke ketoacidosis nwere ike (ibelata ntachi obi na carbohydrates). Ọ dị mkpa ijikwa glucose ọbara ma dozie dose nke gliclazide ma n'oge nchịkwa GCS na mgbe ha kwụsịrị.

Ritodrine, salbutamol, terbutaline (iv) na-abawanye glucose ọbara. A na-atụ aro nchịkwa glucose ọbara ma, ọ bụrụ na ọ dị mkpa, nyefee onye ọrịa na ọgwụgwọ insulin.

Usoro ahịa ọgwụ ahịa

Ogwu gi bu ogwu.

Usoro na ọnọdụ nchekwa

Ndepụta B. Ekwesịrị ịchekwa ọgwụ a na nkụ, gbara ọchịchịrị, na ụmụaka agaghị eru ala na-erughị ogo 25 Celsius. Ndụ shelf bụ afọ 3.

Jiri maka ọrụ imeju na-arụ ọrụ

Na-akpachara anya na imeju ọdịda.

- nnukwu akwara na / ma ọ bụ imeju akwara.

Jiri maka ọrụ ezighi ezi na-arụ ọrụ

Jiri ndị ọrịa agadi

A na-eme ọgwụgwọ naanị na jikọtara obere kalori, nri nwere obere carb.

Ọ dị mkpa ịdị na-enyocha ọkwa glucose mgbe niile n'ọbara na afọ na-enweghị nri na mgbe erichara nri, ọkachasị na ụbọchị mbụ ọgwụgwọ ọgwụ.

Diabetalong® ka enwere ike inye ya ọgwụ naanị ndị ọrịa na-eri nri mgbe niile, nke ha na-agụnye nri ụtụtụ ma na-enye ezigbo carbohydrates.

Mgbe ị na-edepụta ọgwụ ahụ, ekwesịrị iburu n'uche na n'ihi nnweta nke ikike dị iche iche nke sulfonylurea, hypoglycemia nwere ike ịmalite, na n'ọnọdụ ụfọdụ n'ụdị siri ike ma dịte aka, chọrọ ụlọ ọgwụ na nchịkwa glucose ruo ọtụtụ ụbọchị. Hypoglycemia na-etolitekarị nri nwere kalori, mgbe ọ gbasịrị ogologo ma ọ bụ mgbatị ahụ siri ike, mgbe ị alcoholụ mmanya na-egbu egbu, ma ọ bụ mgbe ị na-ewere ọtụtụ ọgwụ hypoglycemic n'otu oge.

Iji zere mmepe nke hypoglycemia, a chọrọ nlezianya na nhọrọ nke usoro onunu ogwu, yana inye onye ọrịa ozi zuru ezu gbasara ọgwụgwọ a tụrụ aro.

Site na oke mmega ahụ na nke mmetụta uche, mgbe ị na-agbanwe nri, ọ dị mkpa ịhazigharị ọgwụ nke Diabetalong®.

Kachasị emetụta ọrụ nke hypoglycemic ọgwụ bụ ndị agadi, ndị ọrịa na-adịghị enweta a nri edozi, na a n'ozuzu ike gwụrụ ala, ndị ọrịa na-enwe pituitary-adrenal ezughi oke.

Beta-blockers, clonidine, reserpine, guanethidine nwere ike kpuchie ngosipụta nke hypoglycemia.

E kwesiri ịdọ ndị ọrịa aka na ntị gbasara ike ịba ụba hypoglycemia n'ọnọdụ ethanol, NSAIDs, na agụụ.

N'ihe banyere ethanol (mmanya), ọ ga-ekwe omume ịmalite ọrịa disulfiram dịka ọrịa afọ, mgbu, ọgbụgbọ, ọgbụgbọ, isi ọwụwa.

Nnukwu ihe ịwa ahụ na mmerụ ahụ, oke ọkụ, ọrịa na-efe efe na ọrịa febrile nwere ike ịchọ nkwụsị nke ọgwụ hypoglycemic nke ọnụ na ịhọpụta ọgwụgwọ insulin.

Mmepe nke iguzogide ọgwụ nke abụọ ga - ekwe omume (a ghaghị ịpụ iche na nke mbụ, nke ọgwụ a anaghị enye nsonaazụ a na-atụ anya na nnọkọ mbụ).

Na-emegide usoro ọgwụgwọ nke ọgwụ Diabetalong®, onye ọrịa ahụ ga-ahapụ ị ofụ mmanya na / ma ọ bụ ọgwụ ethanol nwere ọgwụ na nri nri.

N'oge ọgwụgwọ na Diabetalong®, onye ọrịa ahụ ga-ekpebi ọkwa nke glucose na glycosylated haemoglobin n'ọbara, yana ọdịnaya glucose na mmamịrị.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

N'oge ọgwụgwọ, a ga-akpachara anya mgbe ị na-anya ụgbọ ala ma na-eme ihe ndị ọzọ nwere ike ịdị ize ndụ chọrọ mmụba nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Diabetalong - ntuziaka maka ojiji

Ọrịa shuga bụ ọrịa na-enweghị ọgwụgwọ. A na-eme ka onye ọrịa ahụ medicationsụọ ọgwụ na-edozi shuga ọbara n'oge ndụ ya niile.

Maka ndị ọrịa nwere ụdị shuga 1, nke a bụ insulin, ụdị nke abụọ bụ ọgwụ ndị na-eme ka sulfonylurea.

Diabetalong bụ ọgwụ hypoglycemic ọgwụ enyere maka ndị nwere shuga ọbara dị elu iji belata ya.

A na-ewere ọgwụ ahụ ọnụ, na n'ihi usoro ogologo oge, a na-eji 1, ọ na-erughị ugboro 2 n'ụbọchị.

Edere ọgwụ ahụ dị ka ngwaọrụ nnwere onwe ma ọ bụ na usoro ọgwụgwọ njikọta. A na-eji ya n'ọnọdụ ebe ịgbaso nri anaghị enyere aka, mana ị takingụ ọgwụ ahụ kwesịrị mgbe niile ịgbakwunye ndụmọdụ nri.

Ngwakọta, ụdị ntọhapụ

Diabetalong dị n'ụdị mbadamba ihe ọcha. Ha juru eju na blisters nke iberibe 10 na igbe kaadiboodu, ebe enwere ike iburu efere 3 ruo 6.

Ọgwụ dị na usoro abụọ: 30 mg na 60 mg nke ihe na-arụ ọrụ, nke bụ gliclazide.

Ngwa inyeaka ọgwụ:

colloidal silicon dioxide,
lactose monohydrate,
calcium stearate
pyromellose
ntụ ntụ talcum.

Sdị usoro onunu ogwu nwere ike ịbụ n’ụdị mbadamba ndị nwere ndọtị agbanwetara ma ọ bụ jiri ogologo oge.

Pharmacology na pharmacokinetics

Ngwakọta bụ isi na-arụ ọrụ bụ gliclazide, site na okike ya bụ usoro sitere na usoro nke abụọ sulfonylurea. Gliclazide gosipụtara ọrụ nhọrọ na bioavailability dị elu.

Ọ na - eguzogide gburugburu ebe obibi dị iche iche ma nwee mmetụta ndị a:

na - eme ka insulin na - arụ ọrụ na - eme ka ọ belata ogo nke homonụ a,
normalizes carbohydrate metabolism,
na-abawanye ọrụ nke mkpụrụ ndụ beta pancreatic,
na-ebelata usoro platelet, nke na - egbochi thrombosis na ọrịa nje ndị ọzọ.

Diabetalong na-agbaso kpamkpam mgbe ochichi gachara. Jiri nwayọ na-agbakọta n’ọbara, rute n’uche kachasị awa isii na isii mgbe nlekọta ọrụ gasịrị, na-egosi nsonaazụ ya maka awa iri na 10-12, na ntinye uche ya na-ebelata nke ukwuu ma mgbe awa iri na abụọ gachara ọgwụ kpamkpam.

Gliclazide bụ metabolized kachasị site na umeji, kọọpu ya.

Ihe ngosi na contraindications

Ihe kpatara ịabụ Diabetalong bụ nyocha onye ọrịa - ụdị shuga 2. Edere ọgwụ a ka ọ wedata glucose ọbara mgbe ịdebere ihe mgbochi a tụrụ aro maka nri anaghị enyere aka.

Ọzọkwa, a na-enye ọgwụ ahụ ka ọ bụrụ ọgwụ maka nsogbu nke ọrịa shuga mellitus kpatara, mgbanwe bụ isi na nhazi nke akwara ọbara n'okpuru nduzi nke nnukwu glycemia.

Enwere contraindications maka ọgwụ ahụ, ha gụnyere:

ụdị shuga 1
na-ewere miconazole,
oké ịba ọcha n'anya na akụrụ odida,
oge ime na inye nwa ara,
ọnụnọ nke ketoacidosis na-arịa ọrịa shuga, kokoma ma ọ bụ precoma,
mmetụta dị elu maka ihe mejupụtara ọgwụ ahụ,
mebiri metabolism nke lactose,
ka okenye.

Akpachara anya na naanị n'okpuru nlekọta nke dọkịta, a na-eji ọgwụ ahụ:

na nká
ndị nri ha adịghị agbanwe agbanwe,
ndị ọrịa nwere ọnya obi,
ndị ọrịa na-arịa ọrịa glucose-6-phosphate dehydrogenase,
mgbe ọgwụgwọ glucocorticosteroid ogologo oge,
ndị mmanya na-egbu egbu
inwe akụrụ ma ọ bụ ọrịa imeju.

N'okwu a, dọkịta ga-eme mkpebi dabere na data dịnụ.

Ihe vidio si n’aka ndị na-ere ọgwụ:

Ndị ọrịa pụrụ iche

Maka ndị okenye karịrị afọ 65, enwere ike ịchọ mgbanwe usoro ọgwụgwọ. N'izugbe, a na-eji ọgwụ ahụ eme ihe dịka otu iwu si dị.

N'oge mmegharị ahụ, a na-atụ aro ka ọgwụ insulin dochie ya ruo mgbe nnyefe. Enweghị ahụmịhe iji Diabetalong na ọgwụ ndị ọzọ metụtara glycoside n'oge afọ ime, yabụ ọ gaghị ekwe omume ịchọpụta nsonaazụ ya na nwa ebu n’afọ.

N'oge a na-enye nwa ara, a gaghị enwe ike iji ọgwụ ahụ eme ihe, n'ihi na enwere ohere nke ịmalite ịmịnye hypoglycemia nwa ọhụrụ. N’ihi nke a, amụrụ nwanyị na-arịa ọrịa ara.

Ndị ọrịa nwere ọdịda akụrụngwa na ọrịa ndị ọzọ kwesịrị ịgbaso usoro ọgwụ dị ala, nke kachasị mkpa, ka dọkịta na-ahụ maka nyocha ya.

Ntụziaka pụrụ iche

Ọnọdụ dị mkpa maka ị Diụ Diabetalong bụ nri na-edozi ahụ mgbe niile. O kwesiri ekwenye na ntuziaka maka ndi otu a ma hazie ya n’oge. Nke a dị mkpa iji kpochapụ ihe ize ndụ hypoglycemia, nke nwere ike ime n'ihi enweghị isi ike na ọbara.

Ihe kpatara na - eme ka ọrịa hypoglycemia nwere ike ịbụ:

enweghị onye nlebara anya banyere ọnọdụ ya,
enweghị usoro nke usoro nri na oke nri, agụụ, nri akwadoghị nke ọma.
akụrụ ma ọ bụ imeju akụrụ,
ịdoụ ọgwụ ọdoụ .ụ
oria endocrine,
atughi ime ihe aru oru na aru nke ndi anakpo carbohydrate natara,
nhazi nke ọtụtụ ọgwụ ọgwụ.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Isi mmetụta dị n'ị ofụ ọgwụ bụ:

isi ọwụwa
hemolytic ụdị anaemia,
imebi uto
nfụkasị, na-egosipụtakarị n'ụdị ọnya anụ ahụ.

Oria ndi ozo puru igosi:

ogwe
anya ntughari
imebi nke uche
ịma jijiji
imebi iku ume na oru ilo ihe,
mmụba mgbali elu
ọhụhụ ụzọ
ịba ọcha n'anya nke ụdị cholestatic.

N'okwu a, ọ dị mkpa ịkwụsị ị theụ ọgwụ ahụ wee họrọ analogues dabere na ihe ndị ọzọ.

Do Anụbiga ọgwụ ókè ga-ekwe omume ma ọ bụrụ na inwere onwe gị karịa ị exceedụ ọgwụ ole ị .ụrụ. Isi ihe ọ na-akpata bụ hypoglycemia, ruo coma.

Site na hypoglycemia a na-emepụtabeghị, a ga-ebelata dose ahụ, na ụba nke carbohydrates na nri kwesịrị ịba ụba. N'ihe banyere klaasị hypoglycemic coma, a na-edenye usoro ọgwụgwọ glucose na-emetụta ọbara.

Mmekọrịta na ọgwụ ndị ọzọ

Diabetalong na-emekọrịta ihe n'ọtụtụ ihe, yabụ tupu ịmalite iwere ya, ị kwesịrị ịmara nke a.

Yabụ, ma ọ bụrụ na n'otu aka a na-achịkwa n'otu oge:

na mmanya nwere ike ime ka hypoglycemia,
ya na Danazol, ekpughere oria shuga, nke na -ebilata mmetuta nke ogwu.
na miconazole, a na-eme ka mmetụta nke gliclazide dịkwuo mma, nke nwere ike itinye aka na ịmepụta hypoglycemia, otu ihe na-eme na ndị nnọchianya hypoglycemic ndị ọzọ,
ya na chlorpromazine, nke na - eweputa insulin, a na - ebelata oke oru ya.
ya na tetracosactide na glucocorticosteroids nwere ike iduga mmepe nke ketoacidosis yana mbelata na nnabata carbohydrate,
ya na Wafarin na coagulants ndi ozo n’eme ka aru ya puta.

Nyocha nke ndị dọkịta na-egosi na Diabetalong na-arụ ọrụ nke ọma na mbenata glucose ọbara, agbanyeghị, enweghị ike iji ya mgbe niile.

N'okwu a, analolololo nke Diabetalong, nke dị ọtụtụ:

Diabetalong na Diabeton ka etolitere n’otu ihe eji arụ ọrụ, ma a na-ahụta ọgwụ nke abụọ ka ọ dị irè, ebe ọ bụ na nsonaazụ nke ihe a rụpụtara ngwa ngwa, mana ọnụ ahịa ọgwụ a ji okpukpu abụọ karịa. Glyclazide bụ ihe fọrọ nke nta ka ọ bụrụ analog.

Glucophage nwere metformin n'ime ya, enwere ike ijikọ ya na insulin na ọgwụ ndị ọzọ iji belata shuga ọbara.

Akwukwo ndi ozo ndi ozo choro

Ọrịa shuga na-arịa ọrịa shuga

Ọ bụghị mgbe niile ị ga - enwe ike ijikwa ụdị ọrịa shuga nke ọrịa shuga 2 naanị site na enyemaka nke nri obere carb na ibu. Ọ dịkwa mkpa ịlụso hyperglycemia ọgụ, n'ihi na ọgwụgwọ agụghị akwụkwọ na-eduga ná nnukwu nsogbu.

Otu n'ime ihe ndị kasị dị ize ndụ bụ ọrịa obi. Diabetalong (Latin Diabetalong), ọgwụ hypoglycemic nwere mgbatị ogologo ma ọ bụ gbanwee, ga - enyere aka belata ihe ize ndụ nke ịmalite CVD.

Ohere nke ọgwụ ọgwụ

Njirimara nke ọgwụ antidiabetic nke ọgwụ ahụ bụ n'ihi gliclazide na-arụ ọrụ. Mbadamba ụrọ nwere 30 ma ọ bụ 60 mg nke ihe ndị bụ isi na ihe ndị nwere ya: calcium stearate, hypromellose, talc, lactose monohydrate, colloidal silicon dioxide.

Diabetalong bụ ọgwụ nke klaasị nke anọ na-eme ka ihe na-eme n ’ime mmụọ.

Mgbe ọ banye n'ọbara ọbara, gliclazide na-akpali njikọ nke homonụ endogenous site na mkpụrụ ndụ nke pancreas, na-eme ka itinye glucose ike (na-eme ka ahụ glycogen synthase na-eme ka ahụ dịkwuo ngwa).

N'ime ụbọchị ole na ole site na mmalite nke usoro ahụ, glycemic profaịlụ bụ nkịtị. Oge etiti oge site na nbata nke nri na nri diges ruo na imepụta insulin na-emebi emebi belata, ihe ngosi glycemic nke nri na-akpalite belata.

Ọ bụ ihe na-achọsi ike na afọ 2 mgbe ị theụsịrị ọgwụ ahụ, a na-eme ka ịbawanye uru nke insprandial insulin na C-peptide. Mmetụta anụ ahụ na Diabetalong dị mgbagwoju anya:

Na -eme ka metabolism metabolism,
Ọ nwere mmetụta antioxidant systemic,
Na-akpali insulin insulin,
Ọ nwere mmetụta haemovaskụla (na-egbochi nchịkọta platelet).

Mgbe glucose abanye n’afere ọbara, gliclazide na-arụ ọrụ n’imepụta insulin ngwa ngwa. Site n'ịgwọ ya mgbe niile, ọgwụ ahụ na-adọ aka ná ntị:

Ọrịa microvascular - retinopathy (usoro mbufụt na retina) yana nephropathy (ezighi ezi na akụrụ),
Nsonaazụ Macrovaskụla - ọnya, nkụchi obi.

Njirimara nke Pharmacokinetic

Site na afọ, a na-etinye ọgwụ ahụ n'ụzọ zuru ezu. Ọdịnaya kachasị n’ime ọgbụgba ọbara na-eru mgbe awa 2-6 gachara, yana maka mbadamba nwere MV - awa 6-12.

Mmetụta ọgwụgwọ ahụ na-adịru awa 24, ihe nchebe ọbara glycazide na-ejikọ ọnụ na 85-99%. N'ime imeju, a na-agbanwe ngwaahịa ndu ahụ ka ọ bụrụ metabolites, otu n'ime ha nwere ezigbo mmetụta na microcirculation. Ọkara ọkara bụ awa 8-12, maka mbadamba nkume ndị nwere MB - awa 12-16. Ọgwụ 65% nwere mmamịrị, ọgwụ jiri okpukpo 12% nweta ọgwụ ahụ.

Nsonaazụ

Ihe na-adighi nma maka ogwara nri diges nwere ike ibute nsogbu dyspeptik na iru ura, vomiting, mgbu afo. Site n'akụkụ nke metabolism, hypoglycemia ga-ekwe omume, maka sistem - ọbara - eosinophilia, cytopenia, anaemia. N'akụkụ nke anụ ahụ, enwere ike ịrịa nfụkasị na nyocha ya. Site na akụkụ ahụ ndị nwere mmetụta, enwere mgbakasị uto, isi ọwụwa, ọnwụ nke nhazi, ike gwụ.

Mkparịta ụka ọgwụ ọjọọ

A na-eme ka ịdị mma nke glycoside site na iji ọgwụ anabolic steroid, ndị na-egbochi ACE, β-blockers, cimetidine, fluoxetine, salicylates, MAO inhibitors, Flucanazole, Pentoxifylline, Miconazole, Theophylline, Tetracycline.

A nwere ike ịbelata glyclozide mgbe ejiri ya mee ihe na cobiturates, glucocorticoids, sympathomimetics, saluretics, rifampicin, ọgwụ mgbochi ọmụmụ, estrogens.

Otu esi etinye

Ekwesịrị iji Glycloside nweta nri. Erere mbadamba ihe nile, eji miri rutu ya dika miri. Ihe endocrinologist choputara usoro ogwu ya na usoro ọgwụgwọ ya n’otu n’otu, n’iburu n’usoro banyere oria ya na mmeghachi omume nke ndi oria shuga na ogwu. Maka ọgwụ Diabetalong, ntuziaka maka iji ya na-atụ aro ịmalite mbido nke 30 mg na mgbakwunye mgbakwunye na ụzọ nke mmụba (ọ bụrụ na ọ dị mkpa).

Iji nweta oke ọgwụgwọ ọgwụgwọ kachasị, ọ dị mkpa ịgbaso iwu dị mfe.

A na-ewere ọgwụ kwa ụbọchị otu ugboro, nke kachasị mma - n'ụtụtụ,
Enwere ike idozi ọnụọgụ ọgwụ ahụ n'ime 30 -120 mg / ụbọchị,
Ọ bụrụ na egburu oge nnabata, ị gaghị enwe ike imebi iwu nke okpukpu abụọ site na mgbe ọzọ ọ ga - eme,
Mgbe ị na-agbakọ ọnya, dọkịta na-eburu n'uche ọgụgụ nke glucometer na HbAlc.

Site na arụmọrụ na-ezughi oke, a na-abawanye usoro ahụ (mgbe ya na dọkịta kwechara), mana ọ bụghị tupu otu ọnwa ka ewerechara glycoside nke mbụ. Kwa izu abụọ, na-akwụghị ụgwọ glycemia na-ezughi ezu, ị nwere ike ịbawanye dose ahụ.

Ọ dị mkpa ịtụle na mbadamba 1 nke Diabetalong PV nwere 60 mg nke glyclazide, nke a kwekọrọ na mbadamba 2 nke Diabetalong MV 30 mg nke ọ bụla.

Mgbe ị na-ebufe onye na-arịa ọrịa shuga na gliclazide site na ọgwụ hypoglycemic ndị ọzọ, nkwụsịtụ adịghị mkpa, belụsọ maka usoro sulfonylurea. Uzo mbu na nke a bu ezi - 30 mg, ma oburu na endocrinologist edeputara usoro ya.

N'ime usoro ọgwụgwọ dị mgbagwoju anya, a na-eji Diabetalong na ụdị insulin, biagudins, α-glucosidase inhibitors mee ihe. N'iji nlezianya mee ọgwụ, a na-enye ndị ọrịa shuga ọgwụ ahụ site na otu nsogbu ahụike hypoglycemic (ị alcoholụbiga mmanya ókè, ọrụ siri ike ma ọ bụ egwuregwu, agụụ, ndabere dị oke egwu). Ọrụ hemopoietic na-arịa ya na mmepe anaemia, thrombocytopenia, leukopenia, granulocytopenia.

Nchedo nchekwa

Iji zere hypoglycemia, ọ dị mkpa iji oge eji ọgwụ eme ihe maka iri nri, igbochi nnukwu nkwụsịtụ na nri, iji kwụsị kpamkpam ị ofụ mmanya na-aba n'anya. Oge nlekọta nke ckers-blockers nwere ike imegharị ihe ịrịba ama nke hypoglycemia.

Enwere ike ịmata ọnọdụ hypoglycemic site na isi ọwụwa, nsogbu nhazi, ọgụ na-enweghị nchịkwa nke agụụ, ịda mbà n'obi, ọhụhụ, ọhụụ na-adịghị mma, ọrịa dyspeptik. A na-egosipụtakwa mmeghachi omume nke adrenergic: nchekasị, ọsụsọ, ọdịda ọbara mgbali, ọrịa obi na-efe efe, mgbagha obi. Ọrịa diski diski, ọgba aghara na ụsụ nke mbibi, na mmeghachi omume anụ ahụ (rashes, erughị ala, erythema, urticaria, Quincke's edema) bụ ihe njiri mara.

Agaghị enwe ọgwụgwọ na-aga nke ọma n’etinyeghị obere carb nri. N'ihi ihe egwu dị egwu, ndị ọkwọ ụgbọ ala kwesịrị ịkpachara anya jiri ọgwụ ahụ. Otu ndụmọdụ a na-emetụta ndị nnọchite nke ọrụ metụtara ogo mmeghachi omume dị elu na itinye uche.

Ọkpụkpụ nke imeju na akwara na-akpalite ịba ọcha n'anya, mmụba nke ọrụ enzyme.

Ọ bụrụ na onye ahụ mara ihe, ọ kwesịrị ịra swiiti, aụọ otu iko tii ma ọ bụ ihe ọzọ nwere carbohydrates. Mgbe ọnọdụ ahụ gbanwere, endocrinologist chọrọ nyocha iji dozie dose ma ọ bụ dochie ọgwụ.

Analogues nke ọgwụ

Dabere na ngalaba na-arụ ọrụ maka Diabetalong, analog ga-abụ ọgwụ Glidiab nke ruru ru 140 rubles. Ndị dọkịta nyere Diabeton na Diabeton MV ọgwụ dị elu na ọnụahịa dị elu site na 286 ruo 318 rubles. N'ime usoro synonymic, a na-atụ aro Glyclada.

Nkwadebe nke nwere ụdị hypoglycemic mmetụta dịka Amaril, Glimepiride, Glemaz, Glyurenorm ga-abụ nke ọma na ihe mejupụtara. Edere ha maka hypersensitivity ma ọ bụ ihe mgbochi ọzọ maka glycoside.

Nyocha Diabetalong

Ọria mamiri amụrụla ọrịa Diabetolong, na nyocha na-achọpụta uru ya:

Ndota nke oma nke ihe ngosi glucose.
Ezi ndakọrịta na ọgwụ ndị ọzọ,
Oké ọnụ ọgwụ a na-akwụ maka ya
Ike idalata ibu n’oge ọgwụgwọ.

Ọ bụghị mmadụ niile nwere afọ ojuju na achọrọ njikwa glycemic kwa ụbọchị (ugboro ise kwa ụbọchị), mana oge na-aga, ndị na-egosi ya kwụsiri ike ma nwekwuo njikwa njide onwe onye belata.

Na mkpokọta, Diabetalong bụ ọgwụ ịgwọ ọrịa antidiabetị ịdabere na ya nke na-edozi profaịlụ glycemic. Mgbe ejiri ya n'ụzọ ziri ezi, ọ nwere ike igbochi ihe omume obi na oke nsogbu ndị ọzọ nke ọrịa shuga 2.