Metformin Sandoz > Ọgwụ

Mbadamba ihe mkpuchi.

Njirimara nke anụ ahụ na kemịkal:

Mbadamba 500 mg okirikiri, acha ọcha, mbadamba biconvex, ihe nkiri na-acha uhie uhie, nwere "M 500" n'otu akụkụ ma dị mma n'akụkụ nke ọzọ

Mbadamba mbadamba 850 Mpempe akwụkwọ ọcha, okike gbara agba, nwere “M 850” n'otu akụkụ na ọkaibe na nke ọzọ.

Ngwongwo ogwu

Metformin bụ biguanide nwere mmetụta antihyperglycemic. Ọ na - e belata ma ọkwa glucose mbụ ma ọ bụ ọkwa glucose mgbe erichara ihe na ọbara ọbara. Ọ naghị akpali insulin na-enweghị mmiri ma ọ dịghị akpata mmetụta hypoglycemic.

Metformin na-arụ ọrụ n'ụzọ atọ:

na-eduga na mbelata na mmepụta glucose na imeju n'ihi mgbochi nke gluconeogenesis na glycogenolysis,
na - eme ka nnabata insulin dị nwayọ site na imeziwanye ihe na itinye uru nke glucose na - emegharị ahụ
na-egbu oge ịmịkọta glucose na eriri afọ.

Metformin na - akpali intracellular glycogen synthesis site n'ime ihe na glycogen synthetases. Na-eme ka ikike ibuwanye nke ndị na-ebuga glucose membrane niile (GLUT).

Site n'iji metformin mee ihe, ịdị arọ nke onye ọrịa ahụ kwụsiri ike ma ọ bụ belata obere oge. Na mgbakwunye na emetụta ọkwa ọkwa glucose ọbara, metformin na-emetụta nke ọma na metabolism lipid.

Egwu. Mgbe ịwachara metformin, ọ na-agbadata kpamkpam na ngụgụ nri, 20-30% na-adị na feces. Oge ị ga-eji nweta ntinye kachasị (T _max ) bụ elekere 2.5. Bioavailability dị ihe dịka 50-60%.

N’ime nri n’otu oge, nnabata nke metformin na-agbadata ma were nwayọ nwayọ.

Nkesa. Mgbakwunye protein Plasma bụ nke ileghara anya. Metformin banye n’ime sel ọbara. Oke itinye uche na ọbara dị ala karịa na plasma ọbara, a na-erute ya ihe dị ka n'otu oge ahụ. Mkpụrụ ndụ ọbara uhie na-anọchite anya ụlọ ekesa nke abụọ. Nkezi olu nke nkesa (V _d ) dịgasị iche na lita nke 63-276 lita.

Metabolism. Metformin na-agbanwegharị na mmamịrị. Ahụbeghị metabolites n’ime mmadụ.

Mmechi Mkpochapu akwara nke metformin bụ> 400 ml / min, nke na-egosi na a na-ekepụta metformin n'ihi nchacha mmiri na tubular. Mgbe ị theụsịrị ọgwụ ahụ, ọkara ndụ ahụ bụ ihe dịka awa 6.5. N'ihe banyere ọrụ akụrụ na-emebi emebi, mkpochapu akwara na-agbadata n'ike n'ike, n'ihi ya, iwepụ ọkara ndụ na-abawanye, nke na-eduga n'ịba ụba ọkwa plasma metformin.

Elldị nke abụọ nke ọrịa shuga mellitus (nke na-abụghị insulin) na arụ ọrụ nke usoro ọgwụgwọ nri na usoro mmega ahụ, ọkachasị ndị ọrịa nwere oke ibu

dị ka monotherapy ma ọ bụ ọgwụgwọ njikọta na njikọta ọnụ nke hypoglycemic ndị ọzọ ma ọ bụ na njikọta insulin maka ọgwụgwọ nke ndị okenye.
dị ka ọgwụ monotherapy ma ọ bụ ọgwụ ngwakọta na insulin maka ọgwụgwọ ụmụaka karịa afọ 10.

Iji belata nsogbu ọrịa shuga na ndị okenye nwere ọrịa shuga nke 2 na oke ibu, dị ka ọgwụ nke mbụ nwere nri ịgwọ ọrịa.

Ihe ngbanwe

Hypersensitivity na metformin ma ọ bụ ihe ọ bụla ọzọ nke ọgwụ ahụ,
ọrịa mamịrị ketoacidosis, ọrịa shuga,
ọdịda gbasara akụrụngwa ma ọ bụ arụ ọrụ gbasara akụrụngwa (mkpochapụ creatinine)
Ọnọdụ nnukwu ihe nwere ike ịdaba na dysfunction gbasara akụrụ, dịka:

akpịrị ịkpọ nkụ, ọrịa na-efe efe siri ike, ujo

ọrịa na-adịghị ala ala na nke na-adịghị ala ala nke nwere ike ibute mmepe nke hypoxia:

obi ma ọ bụ akụkụ iku ume ọdịda, infarction myocardial n’oge na-adịbeghị anya, ujo

ọdịda imeju, nnukwu ị alcoholụ mmanya na-egbu egbu, ịhoụbiga mmanya ókè.

Mmekọrịta na ọgwụ ndị ọzọ na ụdị mmekọrịta ndị ọzọ

A naghị atụ aro ka agakọ.

Alcohol intoụbiga mmanya ókè Ejikọtara ya na oke ihe ize ndụ nke lactic acidosis, karịchaa n'ihe banyere ibu ọnụ ma ọ bụ ịgbaso nri kalori, yana imeju imeju.

Iodine nwere ihe eji eme rediopaque nwere ike ibute mmepe nke lactic acidosis na ndị ọrịa nwere ọrịa mellitus megide ndabere nke ọdịda akụrụngwa na-arụ ọrụ. Ekwesịrị ịkwụsị iji ọgwụ ahụ eme ihe tupu ọmụmụ ihe ahụ ekwesighi ịmaliteghachi tupu oge awa 48 ka ọmụmụ ahụ jiri ọgwụ radiopaque na nyocha nke ọrụ mkpo ya.

Ekwesịrị iji nlezianya mee ihe.

Ọgwụ nwere mmetụta hyperglycemic (GCS nke systemic na ihe omume mpaghara, sympathomimetics, chlorpromazine) . Ọ dị mkpa ịdị na-enyocha ọkwa nke glucose na ọbara, oge niile na mmalite ọgwụgwọ. N'oge na mgbe ọ kwụsịrị ọgwụgwọ nkwonkwo dị otú a, ọ dị mkpa iji dozie dose nke metformin n'okpuru njikwa nke glycemia.

Diuretics, ọkachasị akwara looure, nwere ike ịbawanye ohere nke lactic acidosis n'ihi mbelata nke ọrụ akụrụ.

Njirimara ngwa

Lactic acidosis bụ ụkọ metabolic dị ụkọ ma sie ike nke nwere ike ịdapụta n'ihi nchịkọta metformin hydrochloride. A kọwo ọrịa nke lactic acidosis na ndị ọrịa nwere ọrịa mellitus, na nnukwu ọrịa gbasara akụrụ. Ihe ndị dị ize ndụ maka lactic acidosis: ọrịa shuga na-achịkwa nke ọma, ketosis, ibu ọnụ ogologo oge, ị alcoholụbiga mmanya ókè, ọdịda imeju, ma ọ bụ ọnọdụ ọ bụla metụtara hypoxia.

Lactic acidosis nwere ike ime n'ụdị nkwonkwo akwara nke afọ mgbu na oke asthenia. N’ọdịnihu, mmepe nke acid dyspnea, mgbu afọ, hypothermia na coma ga-ekwe omume. Ihe na-egosi nchọpụta ọrịa gụnyere mbelata ụlọ nyocha na pH ọbara, mmụba nke mkpokọta lactate n'ọbara ọbara dị elu karịa 5 mmol / l, mmụba na oge anion na nha nke lactate / pyruvate. Ọ bụrụ na ị na-enyo enyo na lactic acidosis, ị ga-akwụsị ị usingụ ọgwụ ahụ wee kwụọ onye ọrịa ozugbo.

Odida ntaramahụhụ . Ebe ọ bụ na akụrụ ga - emegharị metformin, tupu oge a na - eji metformin, a ga - enyocha ọkwa nke serum creatinine:

ndị ọrịa nwere ọrụ mkpokọta nkịtị ọ dịkarịa ala 1 oge kwa afọ,
ndị ọrịa nwere ọrụ ezumike nka na ndị agadi nwere ọ dịkarịa ala ugboro 2-4 kwa afọ.

Ekwesịrị iji nlezianya mee ihe n'ọnọdụ ọrụ ọrụ akụrụ nwere ike ịnwe, dịka ọmụmaatụ, na mbido ọgwụgwọ nke ọgwụ antihypertensive, diuretics, na mmalite ọgwụgwọ NSAID.

Ndị ọrụ rediopa nwere iodine . Iji ihe ndị na-enye rediopaque eme ihe na-akpata nsogbu nwere ike iduga ọdịda akwara, yana n'ihi nke a, nchịkọta nke metformin na mmepe nke lactic acidosis. Ya mere, dabere na ọrụ akụrụ, a ga-akwụsị iji ihe metformin rụọ awa 48 tupu ma ọ bụ n'oge ọmụmụ ihe ahụ, ọ dịghịkwa emeghari tupu mgbe elekere iri anọ na asatọ gachara.

Gerywa ahụ . Ọ dị mkpa ịkwụsị iji ọgwụ ahụ awa 48 tupu ọrụ ịwa ahụ a na-eme atụmatụ, a na-eme ya n’okpuru, ọrịa azụ ma ọ bụ ọgwụ epidural na a gaghị eweghachi ya tupu mgbe awa 48 gachara arụmọrụ na nyocha nke ọrụ akụrụ.

Childrenmụaka na ndị nọ n'afọ iri na ụma . Tupu ịmalite ọgwụgwọ metformin, a ga-enyocha nchọpụta nke ụdị shuga 2. Dabere na nsonaazụ nke ọmụmụ ọgwụ, enweghị mmetụta nke metformin na uto na uto nke ụmụaka. Agbanyeghị, enweghị data na nsonaazụ metformin na uto ya site na iji ogologo oge, ya mere, iji nlezianya na-atụle paramita ndị a mgbe afọ 10-12 dị, nke a na-eji ọgwụ ahụ eme ihe, karịsịa n'oge uto.

Usoro ndị ọzọ . Ọrịa dị mkpa iji soro usoro nri, oriri nke carbohydrates na-eri ogologo ụbọchị. Ndị ọrịa nwere oke ibu kwesịrị ịnọgide na-agbaso nri obere kalori. Ọ dị mkpa iji nyochaa ndị na-egosi ụlọ nyocha oge niile.

Site na ojiji nke metformin n’otu oge na insulin ma ọ bụ ọgwụ hypoglycemic nke ọzọ (dịka ọmụmaatụ, sulfonylureas ma ọ bụ meglitinide), mmụba na mmetụta hypoglycemic ga-ekwe omume.

Jiri n’oge ime ma ọ bụ n’ịra.

Ọrịa shuga na-achịkwaghị achịkwa n'oge afọ ime (mmeme ahụ ma ọ bụ ịnọgidesi ike) na-ebulite ohere nke ịmalite imebi ọrịa na-emetụta afọ na ọnwụ nke afọ.

Ara. A na-apụpụ Metformin na mmiri ara ara. N'ime ụmụ amụrụ ọhụrụ / ụmụ ọhụrụ, a hụghị nsonaazụ ya. Agbanyeghị, ebe enwere data ezughi oke maka nchekwa ọgwụ a, a naghị akwado inye ụmụ ara ara n'oge usoro ọgwụgwọ metformin. Ekwesịrị ime mkpebi nke ịkwụsị ị takingụ ara na-eburu n'uche mkpa ị needụ ọgwụ maka nne na ihe ize ndụ dị na nwa a.

Ọmụmụ . Metformin emetụtaghị ọmụmụ nke ụmụ nwoke na ụmụ nwanyị mgbe ejiri ya mee ihe na 600 mg / kg / ụbọchị, nke fọrọ nke nta ka okpukpu atọ karịa nke kachasị elu kwa ụbọchị, nke a na-atụ aro maka ojiji mmadụ ma gbakọọ dabere na mpaghara elu ahụ.

Ikike iji metụta ọnụego mmeghachi omume mgbe ị na-anya ụgbọala ma ọ bụ usoro ndị ọzọ.

Ọgwụ anaghị emetụta ọnụego mmeghachi omume mgbe ị na-anya ụgbọ ala ma ọ bụ usoro ndị ọzọ, ebe monotherapy nwere metformin anaghị akpata hypoglycemia.

Agbanyeghị, ekwesịrị iji metformin kpachara anya na njikọta ndị ọzọ hypoglycemic (sulfonylureas, insulin, repaglinide, meglitinides) n'ihi ihe ize ndụ nke hypoglycemia.

Usoro onunu ogwu na nhazi

Monotherapy ma ọ bụ ọgwụgwọ njikọta yana njikọta ọnụ nke hypoglycemic nke ọzọ.

Ndị okenye . Dịka ọ dị, usoro izizi bụ 500 mg ma ọ bụ 850 mg ugboro abụọ kwa ụbọchị n'oge nri ma ọ bụ mgbe nri gasịrị.

Mgbe ụbọchị iri 10-15 gafere, a ga-agbanwe ọgwụ ya dabere n'ihe nhazi nke ogo glucose ogo.

Mmụba na-adịghị ala ala na -ebelata nsonaazụ site na mgbari nri.

Ọgwụ kachasị atụ aro ya bụ 3000 mg kwa ụbọchị, kewara n'ime usoro 3.

N'ihe banyere mgbanwe iji metformin gwọọ ya, ọ dị mkpa ịkwụsị ị agentụ ọgwụ antidiabet ọzọ.

Ngwakọta ọgwụ na insulin .

Iji nweta nchịkwa kachasị mma nke ọkwa glucose ọbara, a pụrụ iji metformin na insulin mee ihe maka njikọta ọgwụgwọ.

Monotherapy ma ọ bụ ọgwụgwọ ọgwụgwọ yana insulin.

Childrenmụaka . Jiri metformin maka ụmụaka gbara afọ 10. Dịka ọ dị, usoro izizi bụ 500 mg ma ọ bụ 850 mg otu ugboro kwa ụbọchị n'oge ma ọ bụ mgbe nri gasịrị. Mgbe ụbọchị iri 10-15 gafere, a ga-agbanwe ọgwụ ya dabere n'ihe nhazi nke ogo glucose ogo.

Mmụba na-adịghị ala ala na -ebelata nsonaazụ site na mgbari nri.

Ogo kachasị akwadoro bụ 2000 mg kwa ụbọchị, kewara 2-3 usoro.

N'ime ndị ọrịa agadi mmebi nke ọrụ akụrụ ga-ekwe omume, ya mere, a ga-ahọpụta dose nke metformin dabere na ntule nke ọrụ gbasara akụrụ, nke a ga-emerịrị oge niile (lee Nkebi " Njirimara ngwa »).

Enwere ike iji ọgwụ ahụ gwọọ ụmụaka site na afọ 10.

Dodoụbiga ya ókè

Mgbe ị na-eji ọgwụ ahụ na ọgwụ nke 85 g, ahụghị mmepe nke hypoglycemia. Kaosinadị, na nke a, mmepe nke lactic acidosis hụrụ. N'ihe banyere mmepe nke lactic acidosis, a ghaghị ịkwụsị ọgwụgwọ ma mee ka onye ọrịa ahụ gaa ụlọ ọgwụ ngwa ngwa. Measurezọ kachasị dị irè maka iwepu lactate na metformin n'ahụ ahụ bụ hemodialysis.

Ozi izugbe banyere ọgwụ hypoglycemic

Onye na-ahụ maka hypoglycemic nwere ihe nwere arụ ọrụ, metformin hydrochloride, nke bụ naanị onye nnọchite klas biguanide. Dabere na usoro onodu ogwu, emeputara mbadamba ihe nke gunyere 500 ma obu 850 mg nke ihe eji eme ihe. Mmetụta ọgwụ ọgwụ nke ihe a jikọtara ya na ikike nke igbochi oruru glucose site na nchịkọta ndị na - enweghị carbohydrate (gluconeogenesis).

Na mgbakwunye na metformin hydrochloride, otu mbadamba ọgwụ ahụ nwere obere stodi sodium, magnesium stearate, silicon dioxide, colloidal anhydrous, copolyvidone Va64 na microcrystalline cellulose.

Ọgwụ anaghị akpalite mmepụta nke homonụ na-ebutelata shuga, yabụ ndị ahụike na-a drugụ ọgwụ a anaghị enwe mmetụta nke hypoglycemia. N'etiti ezigbo Njirimara nke ọgwụ, ọ dị mkpa iji gosipụta ihe ndị a:

Mwepu nke gluconeogenesis.
Cebawanyewanye ike nke mkpụrụ ndụ achọrọ insulin.
Mkpali nke mmanu glucose site na myocytes.
Ibu ibu, ọkachasị n’etiti ndị buru oke ibu.
Mbelata na abamuru nke shuga na ọdịnaya ya mgbe erichara nri.
Mmetụta dị mma na metabolism lipid (ibelata cholesterol, triglycerides na LDL).
Agụụ belatara.
Strekwusi ike glycolysis anaerobic.
Mwepu nke carbohydrates n’ime eriri afọ.

A na-ewere onye na - ahụ maka ọrịa antioxide n'ime, a na-ahụ ịta ahụhụ kachasị mgbe awa 2.5 gachara. Mwepu nke ihe di mkpa na - aputa ihe na nkowa nke diges.

A na-apịpụta Metformin hydrochloride n'ụdị mmamịrị na mmamịrị.

Ntuziaka maka mbadamba mbadamba

Dịka anyị kwuworo na mbido, enwere ike iji ọgwụ ahụ mee ihe maka insulin-based na-abụghị insulin na-arịa ọrịa shuga. Naanị dọkịta nwere ike ịkọwa usoro ọgwụ dị mkpa, dabere na ịba ụba glucose na mgbaàmà ndị metụtara ya na onye ọrịa.

Mgbe ị na-azụ ọgwụ, onye ọrịa ekwesịghị naanị ịgbaso ndụmọdụ dọkịta, kamakwa ịmata ntinye ngwugwu. Ọ bụrụ na ajụjụ bilite, ndị ọkachamara ahụike ya ga-ajụrịrị ha.

Na nmalite ọgwụgwọ, a na-enye usoro ọgwụ dị ala kwa ụbọchị - naanị 500 ma ọ bụ 1000 mg. Izu abụọ ka nke ahụ gasịrị, dọkịta ahụ nwere ike iwelie dose nke ọgwụ ahụ, ma nye ya ọdịnaya shuga dị n'ọbara. Enwere ike ibute usoro ọgwụgwọ mbụ na ọgwụ a site na imebi usoro nri. A na-akọwa ụdị ọrịa a na-adịghị mma site na imeghari ahụ ka akụkụ ahụ nọ n'ọrụ ma mgbe ụbọchị 10-14 gachara onwe ha. Iji kwado ọkwa glucose nkịtị, ị kwesịrị ị na-eri 1,500-2,000 mg kwa ụbọchị. Oke kachasị bụ 3000 mg. Iji belata mmetụta na-adịghị mma nke ọgwụ ahụ na ngịga diges na mbido ọgwụgwọ, ịkwesịrị ikesa usoro onunu ogwu ọtụtụ ugboro.

Site na ijikọta Metformin Sandoz na insulin, enwere ike belata nsonye dị mma karịa ịta shuga. A na-a drugụ ọgwụ a ugboro abụọ ma ọ bụ ugboro atọ n'ụbọchị na 500 mg. Banyere usoro insulin, ọ dabere na ọkwa glucose dị n'ọbara.

Ndị okenye ọrịa shuga na-eji Metformin Sandoz kwesịrị nlebara anya pụrụ iche. Dọkịta na-ekpebi usoro ị theụ ọgwụ ahụ, nyere ọnọdụ akụrụ ya.

Mgbe ị na-azụ ọgwụ, mmadụ ekwesịghị ichefu banyere ịlele ụbọchị gwụ, nke bụ afọ 5.

A na-echekwa ọgwụ a na ebe akọrọ na okpomọkụ nke erughi ogo 25 Celsius.

Metformin Sandoz: Mmekorita Ọgwụ

Ekwesiri icheta na ọgwụ ụfọdụ nwere ike ịkwalite ma ọ bụ belata mmetụta hypoglycemic nke ọgwụ a. Mayfọdụ nwere ike ibute lactic acid coma.

N'akụkụ a, onye ọkachamara n'ọgwụ kwesịrị ịmara ọrịa niile nke ọrịa ya iji zere nsonaazụ na-adịghị mma. Onye ọrịa, n'aka nke ya, ekwesịghị igbochi ọgwụ ndị ọzọ na-abụghị ọrịa shuga.

Ya mere, n'okpuru ebe a, aha ọgwụ ndị belata ịdị irè nke ọgwụ ọgwụ, si otú a na-abawanye ọkwa nke ọrịa glycemia na ndị ọrịa:

Danazole
Chlorpromazine
ọgwụ mgbochi
glucagon,
homonụ thyroid
thiazide diuretics,
usoro nicotinic acid,
nnabata ọmiko
ọgwụ estrogen-progestogen
ndị na-anabata beta-2-adrenergic,
glucocorticosteroids nke ime obodo na usoro.

Enwere ọtụtụ ọgwụ ọgwụ na, n'ụzọ megidere, na-akwalite mmetụta hypoglycemic nke onye na-elekọta antidiabetic. Ndị a gụnyere:

Acarbose.
Ogologo ure na emechara insulin.
Beta-2 adrenergic antagonists.
MAO na ACE inhibitors.
Nchịkwa nke sulfonylureas.
Salicylates.
Nchịkwa nke clofibrate.
Ndị NSAID.
Cyclophosphamide, yana usoro ya.
Oxytetracycline.

Na-eme ka ohere nke lactic acidosis na-a medicationụ ọgwụ na mmanya na ọgwụ ọjọọ nke ethanol, iodine nwere ihe dị iche iche, cimetidine na diuretics.

Ọnụ ego ọgwụ ahụ, nyocha na analogues

Enwere ike ịzụta ọgwụ ahụ n'ụlọ ahịa ọ bụla na ọgwụ dọkịta. Iji chekwaa ego, a na-enye ọgwụ ahụ iwu na weebụsaịtị onye na-ere ere.

Na nkezi, ọnụ ahịa ọgwụ ahụ dị na 230 ruo 800 rubles, dabere n'ụdị ntọhapụ. Yabụ, onye nlekọta antidiedi dị n'akụkụ niile nke ndị mmadụ, nke bụ, bụ uru ya.

Na Internetntanetị, ị nwere ike ịchọta ọtụtụ nyocha dị mma site n'aka ndị ọrịa na-a theụ ọgwụ ahụ. Ọ na-agbadata agbadata ma mee ka ọ dịkwuo mma. Ọ na - enye aka ịkwụ ụgwọ obere ụgwọ frized na ndị ọrịa mamịrị. Onye na-ahụ maka hypoglycemic n'ụdị mbadamba ihe dị mfe iji. Na mgbakwunye, ọ fọrọ nke nta ka ọ ghara ibute nsonaazụ (na mgbakwunye na emeghasịkwa ọnya nri).

Agbanyeghị, enwere nyocha na-adịghị mma banyere ọgwụ. E jikọtara ha na mgbagha nri nke na - ebilite n'oge mmegharị ahụ nke anụ ahụ na - arụ ọrụ. Somefọdụ ndị ọrịa, a na-ekwupụta ụdị mgbaàmà ndị a karịa ndị ọzọ, yabụ na ha ga-eji ọgwụ ndị ọzọ dochie onye nnọchi ọgwụ a na-egbu egbu.

Ndị dọkịta anaghị ekwu na ị ga-enye ndị ọrịa ọgwụ nke ebumnuche na-enweghị oke. Amachibidoro ị toụ mmanya na-aba n'anya n'oge ịgwọ ọrịa.

Oge ụfọdụ ndị dọkịta nwere ịhazigharị usoro ọgwụgwọ ndị ọrịa. Nke a nwere ike ịbụ n'ihi mmeghachi omume na contraindications. Dochie ọgwụ na-akwadoghị nwere ike ịbụ ụzọ nwere otu ihe eji arụ ọrụ, ma ọ bụ nwee ụdị ọgwụgwọ ahụ.

Metformin hydrochloride bụ mpaghara a ma ama n'ụwa, yabụ ejiri ya rụọ ọrụ n'ọtụtụ ọgwụ hypoglycemic. Ọ bụghị ihe ijuanya na Metformin Sandoz nwere ọtụtụ analogues, n'etiti ndị enwere:

Gliformin (112 rubles).
Metformin-Teva (136 rubles),
Glucophage (223 rubles).
Metformin Richter (183 rubles),
Metfogamma 850 (134 rubles), Metfogamma 1000 (168 rubles).
Metformin Zentiva (134 rubles).
Siofor (245 rubles).
Canon Metformin (172 rubles).
Mpempe akwụkwọ (100 rubles).

Dịka ị pụrụ ịhụ, Metformin Sandoz bụ ọgwụ dị irè n'ezie nke na-ewepụ hyperglycemia na ọrịa shuga na ndị ọrịa okenye. Site n'iji ọgwụ a mee ihe n'ụzọ ziri ezi, ị nwere ike ịnọgide na-enwe glycemia nkịtị ruo ogologo oge.

Ndi okacha mara ga-akọ maka ihe Metformin mere n’arụ ọrịa shuga na vidiyo n’isiokwu a.

Usoro nke ime ihe

Metformin ma ọ bụ dimethylbiguanide bụ akụkụ nke ìgwè ọgwụ mgbochi antidiabetic, biguadins.

Kedu ka Metformin si ewelata glucose ọbara? Ọ dị mma ịmara na okwu a ezighi ezi, ọkwa glucose anaghị agbanwe agbanwe, kama nke ahụ, a na-ekesa ya na enweghị nchịkọta. Nke a na - apụta n'ihi ọtụtụ usoro. Nke mbu, Metformin na egbochi mgbochi glucose n’ahụ. N'aka nke ọzọ, ọ na-akpali ire ere. Nke a na - eme n'ihi na Metformin na - egbochi ike na oxygen n'ime sel nke na - eme ka glucose dị, n'ihi nke glucose na - agbaji n'enweghị oke oxygen. Ọrịa glucose na-abanye n’ime sel ahụ site na imepụtakwa mkpụrụ ndụ, sel ndị ahụ na-anabatakwa glucose dị mkpa, a ga-ebibikwa akụkụ nke ihe ahụ kpamkpam.

Ọzọkwa Metformin, ntuziaka maka ojiji, ọ na-akọwa n'ụzọ zuru ezu, na-akpali oriri nke ụlọ ahịa glycogen na imeju na-enweghị iwetulata ọkwa glucose ọbara. Ọ tụgharịrị na Metformin na - enyere aka ịmalite ọrụ glucose dị ka ebe achọrọ ya, na - egbochi ụzọ isi mepụta glucose na - adịghị eduga n'ịgbanwe ọkwa glucose na ahụ.

N’oge ọrịa shuga, oke nke abụba na-abawanye, ibu n’arụ na-ebili. Metformin na - egbochi ike abụba n'efu. Ọzọkwa, oke ibu nwere ike ime n'ihi ọkwa insulin dị elu mgbe niile, n'ihi ihe Metformin, a na-ebelata ọkwa insulin. Usoro a dị ezigbo mkpa maka igbochi nsogbu na arịa nke ahụ.

Metformin na - enyere aka ịbawanye uru nke anụ ahụ na insulin, nke a na - enyere aka ịbanye glucose na akụkụ na anụ ahụ na - arịa ọrịa glucose n'oge ọrịa shuga. Mgbe ị na-a theụ ọgwụ ahụ ihe karịrị otu afọ, onye ọrịa na-enwe mbelata agụụ na oke ibu.

Metformin na-agbaze ọbara, na-ebelata ọkwa nke abụba ndị na-adịghị mma, na-egbochi imebi mgbidi nke arịa ọbara. Nke a na-egosi mkpa Metformin dị na mgbochi nke vaskụla nsogbu nke ọrịa shuga. Ya mere, Metformin na-egbu oge mmalite nke ọrịa angiopathy mamịrị. Yabụ na ị ga - ekpebi oke ihe egwu dị n'ọbara obi ma ọ bụ ọrịa strok n'ọdịniihu site na ịgbakọ ntinye ederede SCORE, ọ bụrụ na kọlesterol daa, ihe egwu belata.

Metformin, ntuziaka maka ojiji, nke a na-egosi nsonaazụ dị mma na mbenata mmalite nke ọrịa shuga, na-eme akụkụ niile nke ọrịa.

Mgbe ị theụsịrị ọgwụ ahụ, a na-achọpụta ọdịnaya kachasị ya na ọbara mgbe awa 2-2.5 gasịrị.

Nreta ziri ezi nke Metformin bụ naanị tupu nri, maka na ọ ga - aka njọ iwe afọ na eriri afọ ma ghara iru ntinye ebe ọgwụgwọ ọgwụgwọ na - apụta.

Ọ dị mma icheta na ị antụ ọgwụ antidiabet na-eme ka ọ bụrụ ihe ezi uche dị na ya naanị ma ọ bụrụ na onye ọrịa ahụ nọgidere na-agbaso na nri nri nke endocrinologist depụtara ma ghara itinye ụdị ndụ ọ bụla, na-eme egwuregwu, na-eme mmega ahụ.

Ihe ngosi maka ojiji

Metformin bụ ọgwụ nwere ọtụtụ ọgwụ, na mgbakwunye na ọrịa shuga n'afọ ndị na-adịbeghị anya, achọpụtara mmetụta ya n'ọtụtụ ọrịa ndị ọzọ.

Ihe ngosi maka ojiji:

2dị nke abụọ nke ọrịa shuga mellitus, naanị otu ọgwụ ma ọ bụ yana ọgwụ ndị ọzọ na-enye antidiabetic nke ndị ọzọ ma ọ bụ insulin,
Ọrịa shuga 2dị 2 na oke ibu. N'okwu mgbe ọ gaghị ekwe omume ịkwụsị ọrịa shuga na ọgwụgwọ na-abụghị ọgwụ (mmega ahụ na nri).

Ngwa nwale

N'oge na-adịbeghị anya, ejirila Metformin na-emewanye ihe na nnwale nke ụmụ nwanyị polycystic, ọrịa imeju na-adịghị egbu egbu, n'oge mgbanwe nwoke na ọrịa na ọrịa ndị ọzọ metụtara nguzogide insulin, dị ka acromegaly, hypercorticism.

Enweghi data zuru ezu na nkwubi okwu sayensị banyere mmetụta nke Metformin na ọrịa ndị a dị n'elu, agbanyeghị, ụfọdụ ndị dọkịta na-ekwu na mgbe nchịkwa Metformin, ọkwa glucose na insulin belatara, mana nke a ezughi ịgụnye ọgwụ ahụ na usoro gọọmentị maka ịgwọ ọrịa ahụ.

Metformin maka polycystic ovary maka ọgwụgwọ nke mkpali ovulation ka bụ n’adighi iwu, dịka ọtụtụ ọmụmụ banyere nsonaazụ ya na arụ ọrụ arụpụtarala arụpụta dị iche iche. Doctorsfọdụ ndị dọkịta, na-eji Metformin maka polycystic ovary na ọrịa shuga, hụrụ na-abawanye na ime ndị ọrịa na-ewere Metformin, n'adịghị ka ndị na-adịghị. Agbanyeghị, ejiri Clomiphene mee ihe n'oge ochie iji kpalite ovulation.

MD Anderson Cancer Center mere nchọpụta buru ibu nke gosipụtara mmetụta Metformin na mgbochi nke ọrịa akwara. Nchoputa nke ihe omumu a gosiputara na uzo 62% nwere ike ibute oria akwara na ndi sonyere omumu tinyere Metformin dika ndi otu ndi oria eweghi. Nke a butere mmalite nke nyocha ọhụụ na mmepe mmemme maka igbochi kansa kansa.

Ngwaọrụ Metformin

Taa, ọ bụ ihe a ma ama n'etiti ndị buru oke ibu na oke oke ibu na-ewere Metformin dịka ụzọ isi belata ibu. Enwere usoro ọgwụgwọ ụfọdụ na Metformin iji gbaa oke ibu. Endocrinologists anaghị adụ onye ọrịa ọdụ ka ha were Metformin n’enweghi ọrịa shuga na mbelata nke inwe mmetụta nke sel na insulin. Ntuziaka maka iji dee banyere ya. Mana ọtụtụ mgbe, ndị ọrịa na-eme nke a n’ejighị dọkịta. Nke a bụ omume dị oke egwu.

Ọ bụrụ na ịhapụ iso nri dị mkpa nke nwere obere glucose, amaghị nke ọgwụ a chọrọ, nwere ike ibute ọtụtụ nsogbu, nke a bụ, nke mbụ. Nke abuo, egosiputara na Metformin emetutaghi onodu glucose obara n’ebe ndi mmadu no, nke putara na obu uzo iji belata ogo nke abuba ga aru oru n’okwu a.

Metformin maka oke ibu, ọkachasị na-enweghị ndenye ọgwụ dọkịta, ka ekwekọrịtara.

Dọkịta nwere ike inye ya ọgwụ naanị ma a bịa n'ihe banyere ọria mamịrị ma ọ bụ na-egbochi insulin. Mana ọbụlagodi na nke a, nri na mmega ahụ na-arụ ọrụ nke ọma karịa ọgwụ Metformin dị. Ntuziaka maka ojiji anaghị akọwa ojiji nke ọgwụ maka oke ibu.

Ntuziaka maka iji hazie ihe ịchọrọ

A na-eji ọgwụ ede ya ma jiri mmiri hichaa ya. Ọ bụrụ na mbadamba nkume ahụ bụ 850 mg - ọ nwere ike isi ike ilo, mgbe ahụ ị nwere ike kewaa mbadamba ahụ ụzọ abụọ. Ọ bụrụ na-achọpụta nsonaazụ mgbe ọ gbasachara, iji kwado ahụ efe ha, enwere ike kee ubochi ọ bụla ka ọ bụrụ usoro 2-3.

Obere opekempe kwa ụbọchị bụ gram 1, kachasi ihe dị kwa ụbọchị bụ gram 3. Abụọ abụọ ruo izu atọ mgbe agbachara ọgwụ ahụ, enwere ike ịbawanye dose ahụ. A na-ahụ ọrụ zuru oke nke ọgwụ ahụ na nsonaazụ ya ka ụbọchị 10-15 gachara.

Ọ bụrụ na ịchọrọ ịmalite ịbanye Metformin kama ị antụ ọgwụ antidiabetic ọzọ, ị ga-akwụsị ị theụ ọgwụ mbụ, wee malite ịmalite ị Metụ Metformin, dịka otu ahụ siri dị.

O kwesiri ka a belata onodu insulin ma oburu na edeputara ya na metformin. Ọgwụ abụọ ahụ na-eme ka hypoglycemic Njirimara nke ibe ha.

Mlọ ọgwụ

Na -akpata akụkụ akụkụ eriri afọ. Enwere ike kpebie itinye uche kachasị mgbe awa 1.5-2 gachara. Ceptionnabata ga-abawanye oge ruo awa 2.5. Ihe nọ n'ọrụ nwere ikike imubanye akụrụ na umeji. Iwepu ọkara ndụ bụ awa 6. N’oge agadi yana ọrụ akwara nwere nsogbu, oge izu ike si n'ahụ ya na-agbatịkwu.

Na-arịa ọrịa shuga

O kwesịrị ka dọkịta dozie usoro ọgwụgwọ ya. Dosebọchị izizi gị bụ 1 mbadamba. N’oge ị kara nká, a gaghị a thanụ ihe karịrị 1000 mg kwa ụbọchị. Mgbe ụbọchị 10-15 gachara, ị nwere ike iwelie usoro onunu ogwu. Anabataghị oke kwa ụbọchị ka o were 2.55 mg. Site n'ọrịa shuga 1, a pụrụ ibelata ọ̀tụ̀tụ̀ insulin kwa oge.

Usoro endocrine

Enwere mbelata ọbara mgbali na ntinye glucose n'ọbara, mgbu akwara, iro ụra.

Dermatitis nwere ike ime.

Mgbe ịwusịrị Metformin 850, mbelata ọbara mgbali elu na-apụta mgbe ụfọdụ.

Ntụziaka pụrụ iche

N'oge usoro ọgwụgwọ, ọ dị mkpa ịlele arụ ọrụ nke imeju, akụrụ ma tụọ njupụta nke glucose na ọbara (ọkachasị mgbe ejiri insulin na usoro sulfonylurea).

Akụkụ nọ n'ọrụ nke ọgwụ na-egbochi mmịpụta nke vitamin B12.

Maka mgbu mgbu, ọ dị mkpa iji chọpụta ọkwa nke lactic acid dị na plasma ọbara.

Mmekọrịta na ọgwụ ndị ọzọ

Usoro nke iwetulata shuga ọbara ji nwayọ nwayọ ma ọ bụrụ na ị were GCS, glucagon, progestogens, homonụ thyroid, thiazide diuretics, adrenaline, ọgwụ nwere mmetụta adrenomimetic, estrogens, antipsychotics (phenothiazines). Ngwakọta ọrụ na-arụ ọrụ nwere mmekorita na-adịghị mma na cimetidine n'ihi mmepe mmepe nke lactacidemia.

Ndị na - egbochi ACE na oxidases monoamine, sulfonylureas, ihe ndị a na - enweta clofibrate, cyclophosphamide, beta-blockers, ndị NSAID nwere ike ịkwalite mmetụta hypoglycemic. Nchikota ya na Danazol na ndi ozo di iche iche nwere ayodiin ka erere.

Wezuga nnabata ma ọ bụrụ na arụ ọrụ imeju adịghị ya.

Were oge ị alcoholụbiga mmanya ókè, gụnyere. amachibidoro iji mmiri amachibidoro.

Ọnụ ọgụgụ ihe na-arụ ọrụ na plasma ọbara na-abawanye 60% mgbe ị na-ewere Triamteren, Morphine, Amiloride, Vancomycin, Quinidine, Procainamide. Ọ dị mkpa iji ọgwụ hypoglycemic jikọtara ya na cholestyramine.

Mmanya ndakọrịta

Alcoholụ mmanya na-abawanye n’ihe ize ndụ nke lactic acidosis. A na-atụ aro ka ewezuga mmanya n'oge ọgwụgwọ.

N'ime ụlọ ahịa ọgwụ ị nwere ike ịchọta onye nnọchi maka ọgwụ a. Enwere usoro analogues na usoro ọgwụ na ihe mejupụtara:

Glyformin
Glucophage na Glucophage ogologo,
Metfogamma,
Mpempe akwụkwọ,
Siofor.

Metformin ọgwụ ahụ si n'aka onye nrụpụta ọzọ nwere ike ịnwe ihe odide Zentiva, Long, Teva ma ọ bụ Richter na ngwugwu ahụ. Tupu ị dochie akara analog, ịkwesịrị ịchọpụta ọkwa shuga dị n'ọbara, gaa nyocha maka ọnụnọ ọrịa ndị ọzọ na ịkpọtụrụ dọkịta.

Metformin Richter: Ntụziaka maka mbadamba mbadamba

A na-ewere mbadamba Metformin - ọgwụ nwere mmetụta hypoglycemic iji mee ka ọgụgụ isi dịkwuo na insulin ma belata nnabata nke glucose na eriri afọ.

Egosiputara ojiji nke Metformin Richter maka udiri oria abuo n’onodu n’enweghi ike iwulite ketoacidosis (karie na ndi mmadu buru oke ibu) n’enweghi ike n’ilebe nri.

Ngwakọta na ụdị ntọhapụ

Ọgwụ (1 tab.) Nwere naanị metformin umi na-arụ ọrụ, akụkụ ya nwere ike ịbụ 500 mg na 850 mg. A na-egosiputa ihe ndi ozo:

Magnesium Stearate
Polyvidone
Aerosil
Copovidone
MCC.

500 mg na ọgwụ ogwu 850 bụ nke elongated, na-acha ọcha. A na-etinye mbadamba na blisters nke 10 PC. N'ime ngwugwu ahụ enwere blister 5.

Ngwongwo na-agwọ ọrịa

N'okpuru mmetụta nke metformin, a na-ahụ na igbochi gluconeogenesis na mkpụrụ ndụ imeju, a na-ebelata nnabata nke glucose site na mgbidi eriri afọ, usoro a na-eji ya eme ihe.

N'otu oge ahụ, mmụba nke ike nke anụ ahụ na ime ihe insulin na-edekọ na-enweghị emetụta mmepụta nke insulin site na mkpụrụ ndụ located-nke dị na pancreas, n'ihi nke enwere ike belata cholesterol, LDL, na triglycerides n'ọbara.

Isi ọgwụ ọgwụ ọgwụ gosipụtara bụ:

Kachasịsịsịsịsịsịsị usoro nke mgbagha mgbaru ọsịị na mbelata nke mkpụkọ umeji
Regulation nke ọkwa thyroid na-akpali akpali
Ihe mgbochi nke gluconeogenesis
Mbibi nke thrombosis
Meziwanye usoro nke resorption nke egbochi mkpụkọ ọbara
Mbelata linoproteins na triglycerides
Cenweta ọnya nke otutu nke abụba
Normalization nke cholesterol.

Mgbe eji mbadamba ụrọ, enwere nnabata ngwa ngwa ihe na-arụ ọrụ nke eriri afọ. Ihe ngosi bioavisible kariri 60%. A na-edekọ mkpokọta plasma kachasị elu mgbe awa 2.5 gachara. Mgbe ị na-eri nri, a na-ebelata ogo a site na 40% na ihe ọ rụpụtara na-egbochi ihe dị ka nkeji iri atọ na ise.

A na-eji Metformin mara maka nkesa ngwa ngwa n'ime akwara, yana usoro metabolic dị ala. Mmekọrịta metformin na protein plasma dị ntakịrị.

A na-ewepu usoro mkpochapu site na ntinye nke sistem. Ọ dị mma ịmara na ọkara ndụ ahụ bụ awa 6.5.

Metformin Richter: ntuziaka zuru oke maka ojiji

Ọnụahịa: site na 162 ruo 271 rubles.

Iri nri riri oke nri ma obu ozugbo. E kwesịrị iji mmiri mmiri were were sachaa ọgwụ. Iji belata ohere nke ịmalite ịrịa ọrịa na-adịghị mma, m na-a drinkụ ihe ọ dailyụ theụ kwa ụbọchị maka 2-3 r.

A na-ekpebi usoro ị drugsụ ọgwụ ọjọọ n’otu n’otu n’inwe ndekọ glucose.

Ceptionnabata ọgwụ ị withụ ọgwụ ọ bụla nke milligram 500: bido gwọọ ya kwa ụbọchị nke 0-1-1 g. enwere ike ịbawanye usoro onunu ogwu mgbe ịchochara glucose. Ọtụtụ mgbe, usoro mmezi kwa ụbọchị anaghị agafe 1.5-2 g, nke kachasị - 3 g.

Ojiji nke mbadamba ogwu nwere ogwu nke 850 milligrams: n'ime ubochi mbu nke ọgwụgwọ, a na-atụ aro ka ị were 850 mg nke metformin kwa ụbọchị. Mgbe ụbọchị 10-15 gachara. dọkịta gị nwere ike ikwu ka iwelie ọgwụ gị. N'oge ọgwụgwọ mmezi, a na-ewere usoro metformin kwa ụbọchị na ọnụọgụ 1.7 g. Usoro ọgwụgwọ kachasị elu ekwesịghị gafere 2.55 g.

Adịghị akwado ndị ọrịa agadi ka ha rie ihe karịrị 1 g nke metformin kwa ụbọchị.

N'ihe banyere nnukwu nsogbu metabolism, enwere ike nke lactic acidosis na-abawanye, nke a ga-achọ mbelata usoro ị theụ ọgwụ ahụ.

Nsonaazụ

Nsonaazụ ndị ọzọ na Metformin dị ụkọ, ọtụtụ oge ị theụ ọgwụ ahụ dị nfe maka onye ọrịa. Ihe kachasị emetụta ya bụ:

ọgbụgbọ
vomiting
obi mgbawa
ime na afọ na-egbu mgbu,
nri riri
a mmetụta nke atọ ụtọ na ọnụ.

Dị ka ọ dị, mgbaàmà ndị a na-amalite na usoro ọgwụ mbụ ma kwụsị ngwa ngwa, ọbụlagodi ma ọ bụrụ na ịgbanweghị ọgwụ Metformin.

N’oge na-adịkarịghị anya, ndị nwere oke mmụọ na ihe mejupụtara ọgwụ ahụ nwere ike ịnweta mmeghachi ahụ nfụkasị ụdị nke erythema na anụ ahụ. N'okwu a, ọ bara uru ịtụle nhọrọ nke ịkwụsị ọgwụ ma dochie ya na onye ọzọ. Achọpụtaghị edema anaphylactic ma ọ bụ Quincke edema na Metformin.

Ọ dịkarịghị, Metformin, ntuziaka maka iji dee maka nke a, nwere ike ibute mmepe nke lactic acidosis. Ya mere, onye ọrịa ahụ kwesịrị ịgakwuru dọkịta oge niile maka nyocha.

Megaloblastic anaemia ma ọ bụ ụkọ vitamin B12 nwere ike ime na mpaghara warara nke ndị ọrịa na-ebute Metformin ogologo oge na ndị ọrịa nwere nnukwu ọrịa siri ike nke eriri afọ na mgbe ọnya afọ gasịrị. Ihe mgbaàmà nke ọrịa megaloblastic anaemia: ụkwara nke akpụkpọ ahụ na akpụkpọ ahụ mucous, adịghị ike nke izugbe, nkụ na akpịrị nke anụ ahụ, ntutu isi, mmetụta nke ụkwụ owu.

N'ime ndị ọrịa nwere hypothyroidism, mbelata homonụ typeotropic ga-ekwe omume. N’ọnọdụ ndị a na-adịghị ahụkebe, enwere ike ibelata testosterone zoro ezo n’ime ụmụ nwoke. Site na ogwu, akpabeghi ihe ogugu abuo ikpe azu.

Mgbaàmà na ihe ize ndụ nke ịdoụbiga mmanya ókè

Formdoụfere Metformin dị ụkọ. N'ime akwụkwọ a, ị nwere ike ịchọta nkọwa nke naanị otu ikpe mgbe ị na-a theụ ọgwụ ahụ na ọgwụ nke 75g. N'otu oge ahụ, ọkwa glucose agbanweghị, mana lactic acidosis mepụtara - ọnọdụ dị oke njọ nke ọkwa lactate dị n'ọbara wee dị elu karịa 5 mmol / l. Ihe ịrịba ama mbu nwere ike:

anya ntughari
isi ọwụwa ruo mmalite nke migraine,
ahụ ọkụ
ihe nkwụsị iku ume
ọgbụgbọ
vomiting
afọ ọsịsa
mgbu afọ
Ọkpụkpụ akwara n’ọkpụkpụ ụkwụ.

Ọnọdụ siri ike nwere ike ibute etolite coma na mkpa ijikọ onye na-eku ikuku.

N'ọnọdụ mgbaàmà ndị dị otú ahụ, ọ dị mkpa ịgwọ onye ọrịa ozugbo ma duzie ule niile dị mkpa nke ga-egosi ọkwa nke lactate, pyruvate na oke ha na ọbara.

Maka iwepụ Metformin ngwa ngwa n'ahụ ahụ, ọ bụ ihe ezi uche dị na iji ọgwụ na-agwọ ọrịa.

Metformin n'oge ime na lactation

N'ime afọ ime, Metformin na - egbochi contraindicated. Enwere ike iwere ya tupu atụrụ ime maka ụmụ nwanyị nwere ọrịa shuga 2 na oke ibu iji mee ka ohere nke ịtụrụ ime na oke belata, ma ekwesịrị ịkwụsị ọgwụ ahụ mgbe ịtụrụ ime. Ọtụtụ ndị dọkịta ka na-edenye Metformin n'oge ọnwa atọ, mana nke a bụ ọtụtụ nsogbu maka nwa ebu n'afọ.

Nke ọzọ, ụmụaka ndị nne mụrụ Metformin n'oge afọ ime ga-adị n'ihe ize ndụ nke ibute oke ibu na ọrịa shuga. Ya mere, ekwuputara na nwanyi kwesiri iwere Metformin n’oge di ime ya oge obula ihe di nkpa ma nweghi ike iji ogwu ozo dochie ya.

Maka atụmatụ ịtụrụ ime, Metformin nwetara aha “ihe dị mkpa” n'etiti ụmụ nwanyị nwere ọrịa shuga, oke oke na oke nke polycystic. Womenmụ nwanyị oke ibu nwere ike inweta ọrịa amụghị nwa. Metformin na-enyere ahụ aka kesaa glucose ma belata ọkwa nke abụba, si otú ahụ mee ka ọnọdụ homonụ ahụ dịghachi ma weghachite usoro ịhụ nsọ nke nkịtị.

Mgbe ị na-enye nwa ara, ọ bara uru ịkwụsị iji Metformin eme ihe.

Metformin maka ụmụaka

Na narị afọ nke iri abụọ na otu, ụdị ọrịa shuga II n'ahụ ụmụaka na ndị nọ n’oge uto ghọrọ ihe a na-ahụkarị. Ọzọkwa, ọrịa ahụ adịghị agabiga ụmụaka dị iche iche na ndị otu dị iche iche. Aroundmụaka gburugburu ụwa na-enwekarị oke ibu ma na -ebelata mmetụta anụ ahụ na insulin. N'oge na-adịbeghị anya, e mepụtala ọtụtụ mmemme maka ọgwụgwọ na-abụghị ọgwụ ọgwụ nke ụmụaka nwere ọrịa shuga na-eguzogide ọgwụ, nke gụnyere nri nri na mmega ahụ. Ka osi di, otutu ihe gha aghaghi igba ogwu. Passzọ ndụ ndụ na nri adịghị mma nke nwere shuga na abụba buru ibu kpatara mmụba nke ọrịa ahụ.

E mechiri Metformin na ụmụaka ruru afọ 15. Mgbe nyocha nke ndị dọkịta America mere n’oge na-adịbeghị anya, nke ụmụaka na ndị nọ n’afọ 10 ruo afọ iri na isii were Metformin ruo izu iri na isii, mbelata nke ogo abụba n’efu na ọbara, mbelata nke ogo lipoproteins dị ala na nke dị ala, triglycerides, na ifelata. N'ime nsogbu ndị a na-enwe, a hụghị hypoglycemia ma lactic acidosis, ihe omume ndị a na-adịghị ahụkebe n'ụzọ ọgbụgbọ ma ọ bụ afọ ọ naghị emetụta nsonaazụ nke ọmụmụ ahụ.

Egosipụta uru nke iji Metformin na nwata gosipụtara, malite na afọ 10 na-enweghị nnukwu nsogbu, mana yana nsonaazụ dị mma na ọdịnihu iji mezuo nchịkwa nke ọrịa shuga ma belata dose ahụ ruo ntakịrị na enwere ike ịkagbu.

Metformin na Vitamin B12

Vitamit B12 ma ọ bụ cyanocobalomin bụ ihe dị mkpa maka hematopoiesis yana ọrụ nke sistem; n'ihi ya, protein na - arụ ọrụ n'ime ahụ.

Echere na iji Metformin ruo ogologo oge, ọgwụ a na-eme ka mmịpụ ahụ na-abawanye n'ụlọ obibi nke vitamin a, nke na-eduga n'ibe ya nwayọ n'ime ọbara ya. N'afọ nke ise nke nnabata, ọkwa B12 na-agbada 5% maka afọ 13 - site na 9.3%.

Okwesiri iburu n’uche na enweghi nsogbu 9% adighi ebute hypovitaminosis na mmepe obara obara ya, kama o na abawanye nsogbu nke oganihu n’iru.

Enweghị ntụpọ nke B12 na-ebute anaemia hemolytic, nke pụtara na mkpụrụ ndụ ọbara uhie na-aghọ ihe na-emebi emebi na oke ọgụ n'ọbara. Nke a na - eduga na mmepe nke anaemia na jaundice. Akpụkpọ ahụ na akpụkpọ ahụ mucous na-acha odo odo, onye ọrịa na-eme mkpesa banyere adịghị ike, ọnụ na -akwụsị, ọnya ụkwụ na ogwe aka, afọ ntigbu, enweghị agụụ, na enweghị nhazi.

Iji chọpụta ọkwa nke vitamin B12, ịkwesịrị ime nyocha ọbara n'ozuzu iji lelee ụdị na sel sel ọbara uhie. Site na ụkọ ọbara ọbara hemolytic na B12, mkpụrụ ndụ ọbara uhie ga-ebuwanye ibu karịa akwara, anaemia, na bilirubin na-enweghị oke ga-abawanye na nyocha nke biochemical.

Ọ bara uru ịhapụ maka enweghị vitamin B12 mgbe ị na-ewere Metformin. Dọkịta gị nwere ike ịnye ọgwụ mgbakwunye na vitamin.

A na-akpa ọchị ma nwee ezi uche, mana ọgwụgwọ nke ụkọ B12 bụkwa nke a na-arụ site na ị na-enye vitamin, na-amalite ugbua.

Ọnọdụ nchekwa

Ekwesịrị idobe Metformin na ebe kpọrọ nkụ, ọchịchịrị, na okpomọkụ nke 15-25. Na nchekwa dị mma, ndụ nchekwa ahụ dịka afọ atọ.
Mee ka ụmụaka ghara iru. Ọ bụ contraindicated iwere mgbe ngafe ụbọchị.

Glucophage bụ analogue mbụ nke Metformin wepụtara na USA.

N'ime nyocha, ọtụtụ bụ ihe dị mma. Convenientzọ dabara adaba iji mee ihe, obere nsonaazụ bụ njirimara ndị na-amasị ndị ahịa. Mkpa nke iji dochie ọgwụ n'oge afọ ime bụ ụfọdụ ihe na-adịghị mma. Ọtụtụ ndị ọrịa nwere ụdị shuga nke 2, polycystic ovary, proiabetes na-ahapụ ọtụtụ nyocha juru afọ banyere ọgwụ.

Ọ bara uru ma dịkwa ọnụ ala iji zụta ọgwụ ahụ ọtụtụ ọnwa, ị nwere ike were ya na ọnụahịa dị mma ma ọ bụrụ na ịzụta ọtụtụ ngwugwu otu mgbe. Nke a ga - ekwe omume, n'ihi na dọkịta ezinụlọ na - achọpụta ịdị irè nke ọgwụgwọ Metformin otu ugboro kwa afọ, ọ bụghị ọtụtụ mgbe.

Tụlee ezigbo nyocha ole na ole:

Mama m nwere ọrịa shuga, yabụ amaara m na ọ dị m mkpa inyocha ọkwa shuga. Mgbe nrụgide ọzọ na-arụ ọrụ, amalitere m inwe obi ọjọọ, achọrọ m ihi ụra mgbe niile, agakwuuru dọkịta. Ọ tụgharịrị na ọkwa shuga dị elu ma dọkịta depụtara m Metformin, ma dụọ m ọdụ ka m nwetụ obere mmega ahụ ma soro usoro nri.
Ọ bidoro ịigụ ihe dị ka milligrams 500 nke Metformin ugboro abụọ n'ụbọchị. Ntuziaka maka ojiji eji nsonaazụ ndị akọwapụtara na mbụ enwere afọ na-ewe iwe na mgbu n'ime afọ. Agbanyeghị, mgbe ụbọchị ole na ole iwere ọnọdụ ọjọọ ndị a, ọ gafere. Achọrọ m iri obere nri mgbe ị na-a theụ ọgwụ. Izu ole na ole gafere ura, wee malite inwe ahụ mma. Mgbe ọ gafere ule shuga ma ya onwe ya bụchaghị ahụ. Metformin nyeere m aka. Ntụziaka ahụ na-atụ aro ị drinkingụ ya naanị otu dọkịta nyere ya, yabụ ewerela ọgwụ ahụ n'onwe gị.

Mgbe afọ 30 gasịrị, ọ malitere iji nwayọọ nwayọọ na-ebukwu ibu, na-anwale ụzọ dị iche iche dị nro iji tufuo ya, mana ihe fọrọ nke nta ka ọ ghara inweta ya. Achọpụtara m na Internetntanetị ị nwere ike iji Metformin maka oke ibu. Ntuziaka maka ojiji anaghị akwado ị theụ ọgwụ ahụ ka ndị mmadụ dị mma, mana ekpebiri m iji ohere. Were ya otu ọnwa, oge nke dara 7 pound. Metformin na-ebelata oke agụụ. Edebekwara ya na nri, ụtọ na ntụ ọka. Afọ juru m na nsonaazụ ahụ, ka ọ dị ugbu a, anaghị adị m oke.

Afọ anọ gara aga, dọkịta chọpụtara ọrịa polycystic ovary syndrome. Alụọla m nwanyị ma n’oge a anaghị m atụrụ ime. Enwere nsogbu mgbe niile na okirikiri ahụ, m nwara ọgwụ dị iche iche, mana ọ nweghị ihe nyeere aka. Mgbe m ghachara agha na intaneti n'otu ebe a na-ahụ maka etu a siri metụta Metformin na ikpe ahụ. Ntụziaka maka iji ọgwụ were ọgwụ mee ihe dị ka ọgwụ antidiabet, mana agụrụ m na a na-agwọkwa polycystosis na nsonaazụ ahụ na-agba ume. Ekpebiri m ịnwale ya.

Aụrụ m ya nwa oge, ma na ngụkọta m na-a itụ ya ruo ọtụtụ ọnwa, na mbụ enwere mmetụta dị na ya, mana emesịa ha gafere. Na nyocha ọzọ, dọkịta ahụ kwuru na enwere akara nke afọ ime. Ekwetaghị m ntị m! Agara m nye onyinye ọbara - mana n'ezie, aga m aghọ nne!

N'agbanyeghị na m drugsụrụ ọgwụ ndị ọzọ, echere m na Metformin nyeere m aka!

Na Russia, ọnụ ahịa ọgwụ na-akwụ dị iche site na 100-220 rubles per blise. Ka anyị leba anya n'umu ahia kariri:

Mbadamba ụrọ Metformin 500 mg, 60 pcs. (onye nrụpụta Gedeon Richter) - 95 rubles,
Mbadamba ụrọ Metformin 500 mg, 60 pcs. (onye na-emepụta Canonfarm, Russia) - 165 rubles,
Mbadamba Metformin-Teva 1000 mg, 30 PC. (onye na-emepụta Teva, Israel) - 200 rubles,
Mbadamba Metformin Richter 500 mg, 60 pcs. (onye na-emepụta Gideon Richter, Hungary) - 215 rubles.

Ego dị na Ukraine site na 22 ruo 380 hryvnia. Ka anyị leba anya n'umu ahia kariri:

Mbadamba ụrọ Metformin 500 mg, 30 PC. (onye na-emepụta Indar Ukraine) - 25 hryvnias,
Mbadamba ụrọ Metformin 500 mg, 60 pcs. (onye na-emepụta Indar Ukraine) - 45 hryvnias,
Mbadamba Metformin Sandoz 500 mg, 120 PC. (onye na-emepụta LEK S.A., Poland) - 280 hryvnias,
Mbadamba ụrọ Metformin Astrapharm 500 mg, 60 pcs. - 45 hryvnia.

Metformin bụ ọgwụ amụrụ nke ọma ejiri n'ọtụtụ ebe, mepụtara n'etiti narị afọ gara aga, ọ ka dịkwa mkpa. Mmetụta ya na metabolism glucose na-agbanwe ụzọ nke ọrịa shuga mellitus, na-egbochi mmepe nke nsogbu vaskụla, nke pụtara na ọ bụ ezigbo mgbochi nke nnukwu myocardial infarction, ischemic na hemorrhagic strok, ọrịa shuga ụbụrụ, neuropathy na nephropathy, na mmepe nke ọrịa mamịrị. Site na iji nke Metformin, ọkwa na ndụ ndụ nke ndị ọrịa mamịrị amụbawo. A na-eme ọmụmụ ihe ọhụrụ kwa afọ ma na-aga n'ihu na-ekpughekwu ohere nke ọgwụ ahụ, mgbe ọ nwere ọtụtụ ọgwụ, taa ọ dị ka ọ na-eso ụwa dum.

Nyocha banyere Metformin 850

A na-anabata ngwaahịa a nke ọma. Ndị ọrịa na-agbaso ntuziaka dọkịta na-ahụ maka ha na-ahapụ nzaghachi dị mma. Na ọnụnọ nke contraindications, a na-ejikarị ọgwụ ahụ, mana emesịa na-ahapụ nyocha na-adịghị mma n'ihi nbibi.

Yuri Gnatenko, endocrinologist, 45 afọ, Vologda

Ngwakọta ọrụ na-arụ ọrụ na-eme ka metabolism metabolism dịkwuo elu, na-akwalite itinye glucose ma na-eme ka ahụ nwee insulin. Na mgbakwunye, ịkwesịrị belata oke nke carbohydrates dị mfe ma rie ọtụtụ eriri. Na-agbaso usoro ọgwụgwọ a chọrọ na ndụ siri ike, ọ ga-ekwe omume igbochi mgbagwoju anya n'ụdị ọrịa obi.

Maria Rusanova, onye na-agwọ ọrịa, dị afọ 38, Izhevsk

Ngwá ọrụ nwere mmetụta ịchekwa insulin. Ọgwụ na-enyere aka belata ibu, melite njikwa glycemic. N ’iwere ọnọdụ, ịta nke biochemical egosi ọbara, haemoglobin glycice, na-ebelata. Iji gbochie nsonaazụ na eriri afọ, ịkwesịrị iwelie onunu ogwu oge 1 n’ime izu abụọ ma ọ dị mkpa.

Elizabeth, afọ 33, Samara

Ọgwụ shuga dị nro. Enyere gi 1 mbadamba nkume ugboro abụọ n'ụbọchị. Ihe onunu ogwu ezuola ime ka glucose di ala. Nsonaazụ gụnyere nsị, stool tọgbọ, ọgbụgbọ na bloating. Amalitere m ị foodụ ọgwụ ọjọọ na ihe mgbaàmà ahụ wee pụọ. Ana m akwado ị drinkingụ mmanya dị ka ntuziaka a si dị.

Diana, 29 afọ, Suzdal

Mgbe onye ọkà mmụta ọgwụ endocrinologist gwara ya, ọ malitere ị .ụ ọgwụ. Ọgwụ ahụ nyere aka belata oke, ịhazi shuga ọbara na ọkwa cholesterol. Metformin nagide ọrụ ahụ na-enweghị nsonaazụ ya. N'ime ọnwa 3 Etuola m kilogram 7. Akpara m gaba n'ihu.

Mkparịta ụka ọgwụ ọjọọ

Enwere mmụba na mmetụta hypoglycemic n'oge a na-eme n'otu oge:

Ndị na-egbochi ya
NWPS
Nkwadebe nke sitere na usoro sulfonylurea, clofibrate
Ndị mgbochi ACE na MAO
Acarbose
Cyclophosphamide
Oxytetracycline
Insulin.

E dere mbelata nke mmetụta hypoglycemic n'oge eji ọgwụ ndị na-esonụ:

COC
Sympathomimetics
Homonụ thyroid
GKS
Ngwakọta nke phenothiazine yana acid nicotinic
Epinephrine
Difọdụ mkpụrụ mmiri ("akaghị" na otu ìgwè thiazide)
Glucagon.

Cimetidine nwere ike igbochi mkpochapụ nke metformin, nke na-abawanye ohere nke lactic acidosis.

Site na iji ọgwụ anticoagulants na-eme n'otu oge, mmetụta nke ọgwụ ndị dabere na metformin nwere ike ibelata.

Alcoholakingụ mmanya na ọgwụ ethanol nwere ike ibute mmepe nke lactic acidosis.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Ohere nwere ike ibute mgbaàmà nke akụkụ:

Afọ akpa umeji: ọgbụgbọ na ọgbụgbọ, ọgbụgba pụtara n'ọnụ, nri na-adịghị mma, afọ mgbu, mgbu azụ.
Metabolism: n'ihe banyere ogologo oge iji - hypovitaminosis B12, adịkarịghị - mmepe nke lactic acidosis
Usoro nke Hematopoietic: ihe mere megaloblastic ụdị anaemia
Usoro endocrine: ọdịdị nke ihe ịrịba ama nke hypoglycemia
Akpukpo ahu: aru aru, nfụkasị ahu.

Achọghị ịdoụbiga ihe ọ withụ withụ n'iji ọgwụ ndị ọzọ ejikọtara na nchịkọta nke sulfonylurea, ethanol na insulin. Ọ na-egosipụta onwe ya na mgbu afọ, afọ ọsịsa, ọgbụgbọ, mkpụmkpụ ume, yana ihe ịrịba ama ndị ọzọ nke lactic acidosis. A na-egosi usoro ọgwụgwọ ọkụ ọkụ iji gosipụta usoro iji belata mfu mmiri ma mezie metabolism.

Ọnụahịa site na 87 ruo 545 rubles.

Gliformin bụ ọgwụ nke so n'òtù ọgwụ biguanide, nke mmetụta hypoglycemic na-egosipụta. Ihe nọ n'ọrụ bụ metformin. Ọgwụ na -ebelata mmịpụta nke glucose na nri diges, nke na-eme ka mmụba nke ike anụ ahụ na insulin. Releasedị ntọhapụ Gliformin - mbadamba.

Uru:

Na-enyere aka belata ahụ
Enwere ike idere ya na insulin
Anabatara iji ogologo oge.

Cons:

Contraindicated n'oge ime na lactation
O kwere omume omume nke ngabiga si na nri diges
Nwere ike kpalite mmepe nke allergies.

Ihe na-enyere Metformin aka. Ntụziaka maka ojiji

Udi: m Mee 7, 2017 ·: 3 · Ọgụgụ: 5 min · Echiche:

Ọgwụ antidiabet nke oge a na-akwalite nnabata kachasị mma nke glucose si n'ọbara - mbadamba Metformin. Kedu ihe ọgwụ na-enyere gị? Ntuziaka maka iji gosipụta na ọgwụ egosipụtara onwe ya na ọgwụgwọ nke ọrịa shuga 2.

Gini bu ihe nkiti

Onye mere ya na ihe mejupụtara ọgwụ ahụ "Metformin" na - egosi isi ihe na - arụ ọrụ - Dimethyl Biguadine. O bu ya bu onye ekere eke n’oru nke kachasi nma n’inweta glucose site n’akwara.

N'ime ihe ntinye aka ka edeputara - starch na mania stearate, yana talc. Ebumnuche ha bụ isi bụ idozi ma kwalite nsonaazụ nke isi ihe na-arụ ọrụ.

Enyere mmetụta ọgwụ ọgwụ

Onye na-anọchite anya obere ngalaba biguanide bụ Metformin ọgwụ antidi na-agwọ ọrịa. Ntuziaka maka ojiji (ọnụahịa, nyocha, a ga-atụle ntụpọ ọgwụ ahụ n'isiokwu dị n'okpuru ebe a) kọwara na ị theụ ọgwụ ahụ so na-eme ka mmachibido glucose dị mma na akụkụ nke imeju. Site na usoro a, hyperglycemia dị adị na-agbadata n'ọbara.

Na mgbakwunye, akụrụngwa na-enye mmụba kachasị mma na nnabata nke ndị na - anabata insulin, na - eme ka nnabata nke insulin na homonụ nke abụba mara abụba, nke na - enyere aka ịbawanye ojiji nke glucose na - emetụta. Na mgbakwunye, a na -ebelata mwepu ya na nri diges.

Ọgwụ "Metformin" n'ụzọ kachasị mma na-agbada ọkwa nke homonụ na-akpali akpali n'ime ọbara ọbara, yana ọkwa nke ịlestụ cholesterol na obere njupụta lipoproteins. Na mgbakwunye, a na-egbochi mgbanwe ọrịa na arịa. Mmetụta ọgwụ ndị ọzọ kwesịrị igosipụta:

mweghachi nke ọbara ọbara,
mmelite nke rheological Njirimara nke ọbara,
Ọ nwere ike bụrụkwa nke thrombosis.

Ọgwụ na-enye mgbazi nke oke ibu na oke ibu na mmadụ.

Mbadamba ụrọ Metformin: ihe ọgwụ na - enyere aka na mgbe enyere ya ọgwụ

Ntụziaka maka ọgwụ a depụtara ọnọdụ ọjọọ ndị a ebe ọgwụ ahụ gosipụtarala onwe ya site n'akụkụ kachasị mma:

ọrịa shuga - nke mbụ ma ọ bụ nke abụọ,
mgbakwunye na akụrụngwa bụ isi na insulin ma ọ bụ ọgwụ shuga ndị ọzọ,
ọrịa shuga monotherapy.

Na mgbakwunye, ọgwụ ọkachamara nwere ike inye onye na-arịa oke ibu oke ọgwụ, ma ọ bụrụ na achọrọ ịchịkwa glucose na usoro ọbara, ọ gaghị ekwe omume iji nweta ụdị ihe ahụ naanị na usoro ọgwụgwọ nri na mmega ahụ.

Ọ ga - ekwe omume iji ọgwụ maka polycystic ovaries - na - agbanyeghị, nlekọta ọkachamara na - arụ ọrụ siri ike, achọrọ nlezianya nke pọdọd glucose.

Ọgwụ "Metformin": ntuziaka maka ojiji na usoro onunu ogwu

Ntụziaka dị na ngwugwu ahụ na ọgwụ ọgwụ ahụ na-egosi na eburu mbadamba nkume ndị ahụ maka nchịkwa ọnụ. Kwesighi ịzọpịa, ghee, ita ha. O zuru ezu ị ilo otu mbadamba, tinyere mmiri zuru oke, ọkacha mma mgbe ị gachara.

Ọ bụrụ na ị theụ mkpụrụ osisi ahụ siri ike n'ihi nha ya, ọ ga-ekwe ka nkewa kee abụọ, bụ nke a na-elo site na ibe ya.

Na mbu, ọgwụ a tụrụ aro ya bụ 1000 mg / ụbọchị, mana iji zere mmerụ ahụ, a ga-ekewa ya na 2-3.

Mgbe ahụ usoro a ga - abawanye - jiri obere oge nke 10-14 ma nyochaa ọdịmma onye ọrịa, plygial glycemic. Ogo kachasị anabata kwa ụbọchị bụ 3000 mg.

N'oge ọgwụgwọ ya na onye na-elekọta ọgwụ "Metformin" nke ndị agadi, a na-atụ aro ka ileba anya na ọrụ nke ụlọ akụrụngwa. A na-enweta arụmọrụ ọgwụgwọ kachasị mma nke ọgwụ ahụ ka ụbọchị 10-14 gachara site na mmalite ọgwụgwọ.

Ọ bụrụ na mmadụ ewerela ọgwụ mgbochi ọ bụla, na mbido nnabata ya ka ọ ga-akwụsị, wee gwọọ ọgwụ Metformin na-amalite na usoro onunu ogwu nke onye okacha mara.

Ọ bụrụ na ọ dị mkpa, ị canụ ọgwụ ahụ nwere ike jikọta ya na insulin, n’ụbọchị ole na ole mbụ, ị doseụ ọgwụ insulin adịghị agbanwe. Ma mgbe ahụ, a ga-eji nwayọ wedata ya - n'okpuru nlezianya nlezianya nke dọkịta na-aga.

Ekeresimesi na nso contraindications

Dị ka ndị ọrụ ọgwụ ọzọ, ọgwụ Metformin nwere ndepụta nke ọgwụ contraindications zuru oke na nke ọ bụla. Ntụziaka edepụtara ndị a:

lactic acidosis guzobere, ma ọ bụ ọnụnọ ya na anamnesis,
ala
ịba ọcha n'anya na arụmọrụ Metformin, nke mbadamba ụrọ nwere ike ibute nsonaazụ,
ọ bụrụ na arụ ọrụ akụkụ akụrụngwa, ma ọ bụ ihe dị adị nke sistem, nke nwere ike ịkpalite ụdị nsogbu a,
adrenal ezughi ezu,
ọrịa ịba ọcha n'anya,
Ọrịa ịba ọcha n'ọrịa
ọnọdụ niile na - adịghị mma nke na - akpalite akpọnwụ nke ahụ mmadụ, dịka ọmụmaatụ, vomiting, afọ ọsịsa, yana hypoxia - ujo, ọrịa obi (cardiopulmonary ọdịda),
a .ụrụma.

Ndị ọkachamara na-ekwusi ike na ọbụna ojiji nke ngwaahịa mmanya na mbadamba Metformin otu oge nwere ike ịkpasu mmebi iwu na metabolic system.

Na mgbakwunye, ị theụ ọgwụ ahụ bụ contraindicated:

ya na oria di iche-iche.
ahụ ọkụ
ọrịa na-adịghị ala ala na ogbo ha lara n'iyi,
ihe mgbochi ọtụtụ ịwa ahụ, yana oge nwughari mbụ sochiri ha,
oge nke imu nwa n’ime nwata ahụ, a na-enye ya ara ga-esochi ya.

Iji kpachara anya, enwere ike ịkwado ọgwụ ahụ "Metformin" na ọgwụgwọ nke ọrịa mamịrị ma ọ bụ n'ụdị ụmụaka. Agbanyeghị, n'ọnọdụ nke a, a ga-ebu ụzọ nyochaa site na dọkịta na-aga ya. Na nsuso glycemic parameters, ọrụ akụrụ.

Mmetụta ndị achọghị

N'ọtụtụ oge, ndị mmadụ na-anabata ọgwụ ahụ nke ọma. N’oge na-adịghị anya, mmetụta ndị a na-achọghị

ọrịa dyspeptik - mkpali nke ọgbụgbọ, ma ọ bụ ọgbụgbọ,
hypovitaminosis B12,
nri riri
ọkụ ọgbụgba, ọnya afọ,
gastralgia,
lactic acidosis chọrọ ịkwụsị ọgwụ,
ọla uto n'ọnụ
megablastic anaemia,
Ọgba aghara na mmiri.

Mgbe ịkwụsịsị mbadamba Metformin, nsonaazụ ya kwụsịrị. Ọkachamara ahụ họrọ ụzọ ọgwụgwọ ndị ọzọ.

Analogues nke ọgwụ "Metformin"

Ngwakọta yiri nke ahụ nwere analogues:

Metformin Richter.
"Metformin hydrochloride."
Nova Met.
"Metformin Sandoz."
NovoFormin.
"Metfogamma 850."
Siofor 500
"Metadiene."
Gliformin.
Siofor 1000
Metformin Richter.
Ọkpụkpụ.
Bagomet.
Siofor 850
"Metfogamma 500."
"Metformin Canon."
Gliminfor.
"Formethine."
"Metformin Teva."
"Langerine."
Glycon.
Glucophage Long.
"Metfogamma 1000."
"Metformin."
"Metospanin."
Sofamet.
"Pliva ike."

Enwere ike ịzụta mbadamba Metformin na Moscow maka 92 - 284 rubles. Ọnụahịa ahụ na Kazakhstan bụ 1190 tenge. Na Minsk, ndị na-ere ọgwụ na-enye otu ihe analog nke “Metformin farmland” maka bel 3-6. rubles. Na Kiev, a na-ere ọgwụ ahụ n'ụlọ ahịa ọgwụ maka 100 - 300 hryvnia.

Nchịkọta dị mma nke ndị mmadụ hapụrụ na nnọkọ ndị metụtara mkparịta ụka nke ọgwụ ịba ụba na-egosi ịdị irè nke ọgwụ Metformin.

Ntụziaka maka ojiji na nyocha nke ndị dọkịta na-egosi na ọgwụ na-enye gị ohere ijikwa oke nke hyperglycemia.

Patientsfọdụ ndị ọrịa na-a Metụ ọgwụ nri Metformin, nke ndị ọkachamara anaghị atụ aro ya.

Otu esi ewere metformin maka oke ibu ma ọ bụ ọnụ ahịa ya

Daybọchị ọma! N'ịchụso njirimara mara mma nke naanị ụmụ nwanyị anaghị anwa anwa, n'agbanyeghị eziokwu ahụ bụ na ụzọ ahụ dị irè ma ọ bụ na-emetụta ahụike dum.

Ma taa, anyị ga-ekwu maka metformin (Richter, Teva, wdg), otu esi ewere ya n'ụzọ ziri ezi mgbe ị na-efufu ibu, nye ntuziaka maka ojiji, yana nzaghachi gị dị ka dọkịta na-arụ ọrụ ọgwụ a mgbe niile.

Enwere m olileanya na mgbe ị gụsịrị isiokwu ị ga-enwe foto zuru oke banyere ọgwụ ị ga-echekwa otu narị ugboro ma ịchọrọ iji ya na ọgụ megide oke ibu.

Metformin: ntuziaka maka ojiji ibu

Iji malite, e mepụtara Metformin na mbụ maka ọgwụgwọ nke ndị ọrịa nwere ọrịa shuga mellitus. Mgbe e mechara, n'oge ọmụmụ banyere ọgwụ ahụ, ekpughere ihe ndị ọzọ gosiri, dịka ọmụmaatụ, ọgwụgwọ nke oke ibu na oke ibu. Mana ọ na - adị irè n’arụ ndị na - enweghị ọrịa shuga? Iji mee nke a, anyị kwesịrị ịghọta etu ọgwụ a si arụ ọrụ na ihe kpatara oke ibu ji apụta.

Ọ bụrụ na ịchọrọ ịmụcha ọrụ niile nke metformin, ana m akwado ka ị buru ụzọ gụọ akụkọ nyocha "Metformin: otu esi arụ ọrụ." N’isiokwu a, agaghị m ekwu gbasara ihe niile dịnụ, mana m ga-ekwu naanị gbasara ndị metụtara ibu dị oke ibu.

N'ihi ihe metformin "na-enyere aka" ifelata

Enwere m ike ikwu na 99% doro anya na ihe fọrọ nke nta ka ọ bụrụ mmadụ niile buru ibu na-ebute nsogbu nke inwe mmetụta insulin n'oge oge.

Insulin bụ homonụ a na-eme ka ọ bụrụ nke na - eso irutu glucose n’ime sel. N'ihi ihe ụfọdụ, sel agaghịzi enweta insulin na glucose enweghị ike ịbanye sel.

N'ihi nke a, enyere pancreas aka ka ọ buru ihe ngosi ka ọ bawanye bawanye insulin ma ọ na-abawanye n’ọbara.

Eziokwu a nwere mmetụta dị oke njọ na metabolism abụba, n'ihi na ịchekwa abụba na-adịwanye mfe.

Ihe kpatara sel ji kwụsị inwe otutu insulin, mana n’ọtụtụ ebe ọ bụ ị nweta oke carbohydrates.

Ejiri glucose kpuchie sel ndị ahụ wee si otú a na-anwa imechi ya n’emeghị insulin. Ọ tụgharịrị na insulin anaghị emejọ ihe ọ bụla, n'ihi na ọ rụrụ ọrụ ya.

N’ihi ya, ọ na-emewanye, ọ na-abụwanye nke na-akpọ asị maka mkpụrụ ndụ nke ahụ. Ọ na-agbanwe usoro ọjọọ nke na-ebute oke ibu, insulin na-eguzogide ọgwụ na hyperinsulinism.

Metformin na-emetụta nguzogide insulin gburugburu, na-ebelata ya ma laghachi na ọkwa okike. Nke a na - ebute sel na - anabata glucose, ọ naghịkwa ekwe ka a gwakọta insulin n'ọtụtụ buru ibu, nke pụtara ịchekwa abụba.

N'ikwu ya n'ụzọ dị mfe, metformin na-arụ ọrụ site n'ime ihe insulin insulin site na iwepu nguzogide insulin. Na mgbakwunye, metformin nwere mmetụta concomitant na-adịghị ike - iji belata agụụ (mmetụta aranrexigenic). Nke ahụ bụ ihe onye ọ bụla na-eche banyere ya mgbe ha malitere ị drinkụ ọgwụ ọjọọ.

Agbanyeghị, nsonaazụ a adịghị ike nke na ọ bụghị mmadụ niile na-ahụ ya. Ya mere dabere na nke a, dị anya site na isi, nsonaazụ nke ọgwụ adịghị ya.

Ọ ga - ejikwa mwepu metformin felata: nyocha nke dọkịta

N’agbanyeghi ezigbo okpukpo okpomoku, n’ihi eziokwu na ọ na - akwalite nnabata nke glucose site na mkpụrụ ndụ, metformin anaghị ebute oke ibu. M ga-ekwudị na nke a bụ nnọọ obere na egosighi.

Ọ bụrụ n’ịche na iwere mbadamba mbadamba abụọ n’ụbọchị, mana n’emeghị ihe ọzọ iji belata ahụ, ị ga-efufu kilogram 30 n’uche, mgbe ahụ aghaghị m imechu gị ihu. Metformin enweghi ihe ndi ahu. Ihe kachasị na ọnọdụ a ị ga-efunahụ naanị kilogram ole na ole.

Ma otu esi ewere metformin maka oke ibu

Ekwesịrị icheta na metformin abụghị ọgwụ anwansi nke na-agbari kilogram gị n'ụzọ ọrụ ebube, ka ọ dị ugbu a ị na-eri achịcha nke iri nke dina n'elu sofa. Site na usoro a, ọ nweghị ngwá ọrụ ga-arụ ọrụ. Naanị mgbanwe mgbanwe n’usoro obibi, nke gụnyere nri, mmegharị na echiche, nwere ike ibute nsonaazụ ezigbo.

Anyị nwere ike ikwu na ụdị ndụ ọhụụ bụ ihe kachasị mkpa, na metformin naanị na-enyere aka. Ọgwụ a abụghị panacea ma ọtụtụ mgbe ị nwere ike ime n’enweghị ya. Nke a anaghị emetụta ikpe ebe enwere oke ibu yana ọrịa shuga. Ma ọ bụrụ na ị nwere naanị oke na enweghị ọrịa shuga, ọ bụ ihe dị na akọnuche na-efulata oke site na ilo ilo ọgwụ, mee ya n'eziokwu.

Kedu metformin ịhọrọ? Metformin Richter ma ọ bụ Metformin Teva, yana ma eleghị anya Metformin Canon

Ugbu a, n'ahịa ahịa ọgwụ, enwere ọtụtụ ụlọ ọrụ na-arụpụta mbadamba nkume ndị dị otú ahụ. Dị ka o kwesịrị, ụlọ ọrụ ọ bụla na-emepụta metformin n'okpuru aha ahia ya, mana mgbe ụfọdụ a na-akpọkwa ya "Metformin", naanị njedebe na-agbakwunye nke na-egosi aha ụlọ ọrụ ahụ. Iji maa atụ, metformin-teva, metformin-canon ma ọ bụ metformin-ọgaranya.

Enweghị ọdịiche dị egwu na ọgwụ ndị a, yabụ ị nwere ike ịhọrọ nke ọ bụla. Enwere m ike ikwu na agbanyeghị otu ụdị arụ ọrụ, ihe ndị ọzọ nwere ike ịdị iche ma ọ bụ na ha ka enwere ike ịhụ ntaramahụhụ ma ọ bụ nfụkasị ahụ, ọ bụ ezie na metformin n’onwe ya nwekwara nsonaazụ. Gụọ akụkọ m tụrụ aro n’elu.

Otu esi a toụ metformin maka oke ibu

Shouldkwesiri ịmalite site na obere ọgwụ nke 500 mg otu ugboro. Ọgwụ nwere ọgwụ dịgasị iche - 500.850 na 1000 mg. Ọ bụrụ na ịchọrọ ịmalite na nnukwu ọgwụ, ị ga-enwe obi ụtọ niile nke nsonaazụ, nke bụ nsogbu nke dyspeptik ma ọ bụ, na Russian, nsogbu nri nri. Dịkwuo 500 mg kwa izu.

Oke kachasị kwa ụbọchị nwere ike ịbụ 3,000 mg, mana dịka iwu, ndị dọkịta na mụ n’etiti anyị nwere oke ruru 2,000 mg.Karịa ego a, arụmọrụ ahụ pere mpe, nsonaazụ ya na-abawanye.

A na-a drugụ ọgwụ ahụ n'oge nri ma ọ bụ mgbe nri gasịrị. Edebere ya tupu oge ịrahụ ụra - ọnọdụ a dịkwa mma ma nwee ebe ịnọ. Ọ bụrụ na nsonaazụ dị n'akụkụ pụtara ma ghara ịgafe mgbe izu abụọ gachara site na mbido nchịkwa, mgbe ahụ ọgwụ a adabaghịrịrị gị ma ekwesịrị ịkwụsị ya.

Metformin: nyocha nke ifelata

Adịghị m umengwụ ma arịgo na nnọkọ na saịtị ebe a na-enwe nkwukọrịta n'etiti iwelata ibu na ebe ha na-akọ ahụmahụ ha. Arịrịọ a na-etinye ike nke metformin ozugbo.

Ana m enye gị nyocha nke ndị mmadụ ka ị ghara ịchọ ha na netwọkụ. Imirikiti nyocha na-adịghị mma. Ndị dị mma na-akwalite ụdị ọgwụ ụfọdụ ma ọ bụ na-eji ụzọ ndị ọzọ na-abụghị metformin.

Anaghị m akọwa iwu nke ọma; na ha nwere ike nwee njehie dị iche iche.

Nyocha Nke 1 (na nkwenye nke okwu m)

Gee ntị, ma ọ bụrụ na ị na-agbaso ndụmọdụ nri na metformin .. mgbe ahụ metformin n'onwe ya adịghị mkpa))))))))

Nyocha Nke 2 (na abụghị maka ndị ọrịa mamịrị niile)

Mama m, onye ọrịa shuga, na-a metụ metformin. Ọ chọghịkwa ka ihe ọ bụla funahụ ya. = -)))))))))) ojo ozo.

Nyocha Nke 3 (nsonaazụ efu esitekwala na ya pụta, ihe bụ isi bụ imezu nkwubi okwu)

Ekpebiri m ị drinkụ Metformin iji felata, n'ihi na ihe ekwesịrị na-egbochi carbohydrates. Ana m a dụ dị ka ntuziaka ndị a si dị, ji nwayọọ nwayọọ na-abawanye usoro onunu ogwu. Ekwesịrị m ikwu ozugbo na enweghị m ọrịa shuga ma ọ bụ ọrịa ọ bụla n'ozuzu ị toụ ya dabere na ngosipụta.

Ma, n'eziokwu, ahụghị m mmetụta ọ bụla mgbe ọnwa gasịrị. Mmadu dere na o nweghi nsogbu ojoo, na inwere ike oria ma oburu n’a drinkuru ihe n’enyeghi. Ihe niile dị m mma, ma ọ bụ, na enweghị ụzọ ọ bụla - na m whatụọ ihe m na-enweghị. Eleghi anya ọ dị mma dịka ọgwụ, mana maka ịbelata ibu - 0.

Ya mere enweghị m ike ikwu n'ezie ma m na-akwado ya ma ọ bụ na m akwadoghị. Ma maka ịta ahụ dị oke, hoo haa.

Nyocha Nke 4 (nwere mmetụta)

Onwe ya, usoro a emetụtaghị m, nsogbu m na-emetụta, yana ọgbụgba anaghị apụ apụ ma ọ bụrụ na belatara ọgwụ ahụ, m ga-akwụsịtụ ụzọ. Anaghị anwa anwa.

Nyocha Nke 5 (anaghị arụ ọrụ na-enweghị nri)

Aụrụ m ihe ọ indicụ toụ n'ihe ngosipụta ọgwụ, etufulatara ya n’erighị nri. N'iji nri, n'ezie, enwere m ifelata, mana glucophage enweghị ihe gbasara ya

Yabụ, echere m na onye ọ bụla ghọtara na usoro metformin abụghị ọgwụ ogwu dị ịtụnanya ma ọ bụ mgbakwunye nri eji emeju nri, ọ bụghị abụba ọkụ, ọ bụghị ihe mgbochi carbohydrate na eriri afọ, mana ọgwụ siri ike nke nwere ihe ngosi ya.

Isi okwu m choro ime ka ị mata bụ na metformin agaghị enyere aka n’agbanweghị nri, kama dịka ọgwụ ndị ọzọ iji lụso oke ibu ọgụ.

Site na metformin na ụdị ndụ ọhụụ, ifelata bụ ihe ọchị karịa, n'ụzọ ụfọdụ ọ ga - adị mfe.

Ma ebe enwere ohere iji nweta nsonaazụ na-enweghị ọgwụ, yabụ na ị gaghị adị mkpa ịmalite ozugbo ị drinkingụ metformin? Obere kemistri putara ihe ahu ike! Nke ahụ bụ ihe niile. Idenye aha ịnata edemede ọhụrụ site na ozi-e wee pịa bọtịnụ ndị na-elekọta mmadụ n'okpuru isiokwu a.

Site na ikpo ọkụ na nlekọta, endocrinologist Lebedeva Dilyara Ilgizovna

* Ihe omuma a emetụtaghi ndi mmadu nwere ngwakọta nke oke ibu, oria mamria ma obu oria ndi ozo nke metabolism metabolism. Ceptionmata metformin na nke a na-abụ ihe ngosipụta sitere na ya, dị ka hypoglycemic.

Ogwu hypoglycemic ọgwụ

Leasedị mwepụta, ihe mejupụtara na nkwakọ

Mbadamba ụrọ gbara agba acha ọcha, gburugburu, biconvex.

Taabụ 1metformin hydrochloride 500 mg

Ndi ozo: povidone K90, stachi ọka, crospovidone, magnesium stearate, talc.

Ihe mejupụtara shell: methaclates acid na methyl methacrylate copolymer (Eudragit L 100-55), macrogol 6000, titanium dioxide, talc.

10 PC. - blisters (3) - ngwugwu nke kaadiboodu.

Omume ọgwụ

Metformin na - egbochi gluconeogenesis n'ime imeju, na - ebelata nnabata nke glucose site na eriri afọ, na - eme ka ojiji nke glucose na - emejuwanye oge, na - emekwa ka ọ nwee mmetụta nke anụ ahụ na insulin.

Ọ naghị emetụta nzuzo nke insulin site na mkpụrụ ndụ beta nke pancreas, anaghị akpata mmeghachi omume hypoglycemic. Na-ebelata ọkwa nke triglycerides na obere linoproteins dị ala n'ime ọbara. Na-eme ka ahụ gị dị ike ma ọ bụ belata ya.

O nwere mmetụta nke fibrinolytic n'ihi mkpochapụ nke plasminogen activates inhibitor anụ ahụ.

Mkparịta ụka ọgwụ ọjọọ

Ekwesighi ka eji Danazol eme ihe oge a iji zere uto hyperglycemic nke ikpeazụ. Ọ bụrụ na ọgwụgwọ na danazol dị mkpa ma kwụsịchaa nke ikpeazụ, a chọrọ ndozi nke metformin na ayodiin iji chịkwaa ọkwa nke glycemia.

Njikọ ndị chọrọ nlekọta pụrụ iche: chlorpromazine - mgbe ewere ya na nnukwu doses (100 mg / ụbọchị) na-abawanye glycemia, na-ebelata ntọhapụ nke insulin.

Na ọgwụgwọ nke ọgwụ mgbochi na mgbe ịkwụsịsịrị ịhapụ nke ikpeazụ, achọrọ ịgbatị dose nke metformin n'okpuru njikwa glycemia.

Iji otu ihe eji eme ihe na usoro sulfonylurea, acarbose, insulin, NSAIDs, MAO inhibitors, oxygentetracycline, AC inhibitors, clofibrateeri, cyclophosphamide, β-blockers, ọ ga-ekwe omume ịbawanye hypoglycemic mmetụta nke metformin.

Site na iji GCS eme ihe n'otu oge, mgbochi ogwu a na-aralụ a ,ụ, epinephrine, sympathomimetics, glucagon, homonụ thyroid, thiazide na loop diuretics, ọgwụ phenothiazine, usoro nicotinic acid, mbelata mmetụta hypoglycemic nke metformin ga - ekwe omume.

Cimetidine belatara mkpochapu nke metformin, nke na-abawanye ohere nke lactic acidosis.

Metformin nwere ike ịkụda nsonaazụ anticoagulants (ọgwụ coumarin).

Mmanya na-aba n'anya na-eme ka ohere mmadụ nwere ịrịa lactic acidosis n’oge ị alcoholụbiga mmanya ókè, karịchaa n’ihe metụtara ibu ọnụ ma ọ bụ ịgbaso nri kalori, yana ọrịa imeju.

Ime na lactation

Mgbe ị na-eme atụmatụ ịtụrụ ime, yana n’oge ime n’oge ị na-ewere Metformin, ekwesịrị ịkagbu ya, ekwenyekwa ọgwụ insulin. Ebe o bu na enweghi data banyere banye n’ime mmiri ara, a na - enye ogwu a n’ime mmiri ara. Ọ bụrụ n’ịchọrọ iji Metformin n’oge na-enye nwa ara, a ga-akwụsị ịhapụ inye ya ara.

Usoro na ọnọdụ nchekwa

Chekwaa n’ebe kpọrọ nkụ, ọchịchịrị na okpomọkụ nke 15 Celsius ruo 25 Celsius. Ekwela ka ụmụaka ghara iru ya. Oge ichere bu afọ ato.

Nkọwa nke ọgwụ METFORMIN dabere na ntuziaka akwadoro maka ojiji nke ndị nrụpụta kwadoro.

Chọta ahụhụ? Họrọ ya wee pịa Ctrl + Tinye.

Metformin Sandoz 500 mg na 850: ọnụahịa, nyocha

Metformin Sandoz bụ otu n'ime ọgwụ ndị a ma ama nke a na-eji ma ọrịa shuga Idị nke mbụ yana ntụtụ insulin na maka ụdị ọrịa II, mgbe agụmakwụkwọ nkịtị na nri na-edozi ahụ anaghị ibelata ọkwa glucose.

N'ihi ihe ndị dị n'ọrụ, mbelata shuga na-eme n'ọbara ọbara, a na-ebelatakwa uru nke glucose na-ebelata.

Dị ka ị maara, ọgwụ ọ bụla nwere ọtụtụ contraindications, mmetụta ndị ọzọ na njirimara ọgwụ ndị ọzọ. Ya mere, ọ dị mkpa ịmara ọtụtụ ozi dị ka o kwere mee banyere ọgwụ a na-a .ụ. Etu esi eji ogwu a?