Na 1930, Frey buru ụzọ jiri trasilol kallikrein inactivator nwee ihe ịga nke ọma n'ịgwọ ọrịa pancreatitis. Ihe mbu nke nchekwa ọcha bu nke M. Kunitz na J. H. Norlrop nwetara na 1936 site na pancreas nke anumanu.

Ihe ndi mmadu na - eme bu ihe ndi mmadu na - egbochi ihe ndi mmadu na - egbochi ihe ndi mmadu na - enyocha ha. Ruo ugbu a, ebipụtala ihe karịrị ọrụ 2,000 na ojiji nke antienzyme maka ọgwụgwọ nke nnukwu ọrịa ọrịa pancreatitis, ma n'ụlọ ọgwụ ma na nnwale. Agbanyeghị, enweghị nkwekọrịta gbasara izi ezi nke pathogenetic nke iji ha, ịdị irè, usoro ọgwụgwọ, ụzọ nchịkwa. Ọtụtụ ndị na-awa ahụ kwenyere na ojiji nke inhibitors adịghị enye mmetụta, na-ezo aka n'eziokwu ahụ na nkwadebe mgbochi, ọbụlagodi na nnukwu usoro, anaghị egbochi usoro necrotic na gland na para-pancreatic fiber. Site n'ụdị edere nke ọrịa pancreatitis, ojiji nke trasilol na nkwadebe antienzyme adịghị ka ezighi ezi site na ụlọ nyocha ma site n'echiche akụ na ụba. Agbanyeghị, iji ihe ndị na - egbochi nchebe na - ekwenyeghị ka ahapụ ya kpamkpam.

Ahụmahụ nke ndị ụlọ ọgwụ na nke mba ọzọ na-egosi na proteolysis na-egbochi mgbochi kinin na autolysis site na inactivating trypsin, kallikrein, chymotrypsin na plasmin. Anyị chọpụtara na site n'enyemaka nke ndị na - egbochi ọ bụrụ na ọ ga - ekwe omume iwepụ ndị ọrịa na ujo, toxemia, iji melite ọnọdụ izugbe ma mezie ụfọdụ usoro biochemical. Na mgbakwunye, a maara na nkwadebe mgbochi na-egbochi esterase, ihe nchebe na ọrụ kininogenase nke plasma na pancreatic kallikrein.

Mgbe nchịkwa nke nkwadebe antienzyme nye onye ọrịa ruo minit 5, usoro mgbagwoju anya inhibitor-enzyme na-adịghị arụ ọrụ (Werle, 1963). Nkeji iri isii na iteghete nke ọgbụgba ahụ na-ebelata ihe inhibitor n’ime ọbara na-ebelata, ebe ka ọ dị ugbu a akụrụ nwere ntakịrị ihe karịrị 50% nke inhibitor injection. Ihe mgbochi enzyme zuru oke ka ana-ahụ naanị n'ihu ọnụnọ nke mgbochi.

E guzobere ya na nnwale na ihe ruru 98% nke antienzymes n'ụdị ihe dị mgbagwoju anya bụ akụrụ na-esi n'ahụ mmadụ wepụta. Ekwenyere na trasilol na analogues inhibit fibrinolysis, na-egbochi ọrụ kininogenin (kallikrein) na anụ ahụ, na-egbochi ọrụ metabolic nke gland parenchyma, na-emetụta microcirculation na oxygen oxygen nke anụ ahụ, inhibit elastase, chymotrypsin ozugbo na pancre. Ọkara ọkara nke trasilol, kontrikal na ihe nchebe ndị ọzọ sitere na ọbara bụ awa 2. Ya mere, a ghaghi inye nkwadebe antienzyme ugboro ugboro. Ọdịiche dị n'etiti nchịkwa ekwesịghị ịgafe awa 3, na ọkwa nke inactivator kwesịrị ịdị elu karịa ọkwa enzymes proteolytic. N'akụkụ a, ogologo oge nchịkwa nke obere ọgwụ mgbochi na-egbochi adịghị arụ ọrụ ma ọ nweghị arụ ọrụ. Kwa ubochi inhibitors kwesịrị ikpebi iburu n'uche ọkara ndụ ha site na ọbara (awa 2). Ekwesịrị inye ọgwụ kachasị maka antienzyme n'ụbọchị mbụ nke ọrịa.

Dabere na data anyị (Mayat B.C. et al., 1976), dabere na nyocha nke nsonaazụ ọgwụgwọ nke ndị ọrịa 107, nchịkwa intravenous nke nkwadebe antienzyme ọbụlagodi na nnukwu usoro ọgwụgwọ anaghị akwụsị mmalite nke ọrịa akwara. Ọ dị mkpa ịmara na arụ ọrụ nke ndị gbochiri egbochi bụ oge ọ gafegoro site na mbido ọrịa ahụ ruo n'oge eji ha na usoro nke ọgwụ a na-enye. Dabere na ọtụtụ ndị ụlọ ọgwụ, ekwesịrị ịhazi ọgwụ antienzyme na 6 awa mbụ site na mmalite nke ọrịa ahụ. Enwetara nsonaazụ na-agba ume karị site na ntinye nke ndị na-egbochi ya ịbanye na eriri celiac. Saveliev B.C. (1983) na-atụ aro nchịkwa nchịkwa nke nhazi antienzyme na oge awa 3-4.

G.P. Titova (1989) chọpụtara na ndị na-egbochi nchekwa na nnwale nnwale anaghị amachi oke mbibi gland na iwepụ nsogbu ọgbụgba nke mpaghara.

N'ime usoro ọgwụgwọ, ndị na-egbochi nchebe nchebe ndị a zuru ebe niile: Ọgụ, Trasilol (Germany), Gordox (Hungary), Pantripin (Russia), Tsalol (Italy).

Esemokwu bụ ọgwụ dịpụrụ iche na ngụgụ nke ehi. Ọ na-egbochi ọrụ nke trypsin, kallikrein, plasmin. A na-eji ya eme ihe ma tinye ya na nkeji antitrypsin (otu 1 na - egbu 6 μg nke trypsin). Otu ụzọ maka ọrịa pancreatitis siri ike bụ 20,000 nkeji, kwa ụbọchị - 60,000 nkeji. Usoro ọgwụgwọ ya dị 500,000-700,000 nkeji. Enwere ike iji ọgwụ ahụ mee ihe site na chipping parapancreatic fiber.

A na - enweta trasilol site na gland nke anụmanụ. Ọgwụ ahụ na-egbochi ọrụ nke plasmin, kallikrein, trypsin na enzymes ndị ọzọ na-echebe. Ọzọkwa, ọ na-emetụta trypsin nọ n'ọrụ ugboro 4 adịghị ike karịa ọrụ nke kallikrein. Ọkara okirikiri nke mgbasa ya n’ime ọbara bụ nkeji 150. Ejiri ya na ogwu: 50,000-75,000 nkeji, n'ọnọdụ ndị siri ike - ruo otu narị puku, ka a na-achịkwa ya mgbe ọ bụla na 250-500 ml nke 5% glucose ngwọta. Maka usoro ọgwụgwọ - nkeji 400000-500000. Usoro ọgwụgwọ antienzyme na-ejedebe site na ụbọchị 7-10.

A na-enweta Gordox, dị ka trasilol, site na gland nke anụmanụ. Tinye ntinye n'ime. Dịka ọgwụ izizi, aga-ahazi nkeji 500,000 nwayọ nwayọ, mgbe ahụ, nkeji 50,000 kwa awa-mmiri. N’ụbọchị na-esote mmezi ahụ, a ga-eji nwayọ belata nha kwa ụbọchị rue 300,000-500,000.

A na-enweta Pantripin site na pancreas nke ụmụ anụmanụ. Otu akụkụ ya kwekọrọ na 800 IU nke trasilol. Thebọchị kwa ụbọchị bụ nkeji 300, n'ụdị siri ike - ihe ruru 400-500 n'otu oge.

A na - enweta Tsalol site na parotid glands nke ehi. Otu usoro - 25,000 nkeji, kwa ụbọchị - 50,000 nkeji. Banye intraven. Usoro ọgwụgwọ ya dị nkeji 300000-400000.

Enwere ike ịmebata ndị na - egbochi ihe ọ bụla n'ime akpa nri, retroperitoneally n'oge ịwa ahụ.

Ọnọdụ ndị a na-ejikọ ndị na-egbochi ya. Enwere ụfọdụ ntụaka maka anaphylactic na mmeghachi ahụ nfụkasị anụ ahụ, mmepe nke thrombophlebitis n'akụkụ veins. P. Kyrle (1962) hụrụ mmepe nke pseudocysts na abịaghị.

Mgbe ị na-edepụta usoro ọgwụgwọ ọrịa maka ndị ọrịa nwere ọrịa pancreatitis, a ga-agbaso ụkpụrụ ndị a: 1) ịtụle ihe oge (nyocha nke mbụ, ụlọ ọgwụ na ọgwụgwọ), 2) ịtụle ọgwụ na ụdị ọrịa akwara, 3) mmalite nke usoro ọgwụgwọ antienzyme dị elu, 4) ojiji ụzọ nchịkwa nke ndị na - egbochi (Savelyev BC et al., 1976).

Intzọ mgbaafọ nke nchịkwa nke ndị na-egbochi nchebe, anaghị enye ohere iwepụta ọtụtụ n'ime ha na pancreas. Iji meziwanye nsonaazụ ọgwụgwọ B.C. pancreatitis Saveliev (1976), Yu.A. Nesterenko et al. (1978) tụrụ aro maka nlekọta nke ndị na-egbochi intra-aortic ma ọ bụ site na catheterization nke mkpụrụ ndụ celiac dịka Seldinger-Edman siri kwuo. N'ime ụlọ ọgwụ, K.N. bu ụzọ tinye usoro a n'ọrụ. Grozinger na Wenz (1965). Ọ bụghị ewu ewu ugbu a.

B.C. Briskin et al. (1989) mere ọgwụgwọ intra-aortic na ndị ọrịa 92 nwere nnukwu ọrịa pancreatitis. Catheterized okporo osisi celiac ma ọ bụ elu akwara ozi, obere mgbe ahụ arteries. Ngwakọta nke ngwakọta ọgwụ gụnyere: gelatin, polyglucin, albumin, yana enweghị spa, papaverine, nnabata, ọgwụ nje, gordox (600 000-800 000 nkeji kwa ụbọchị). Ogo nke infusion dabere na BCC ma site na 2000 ruo 3500 ml kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, a na-etinye mmiri na ọgwụ ndị ọzọ mgbe ọ bụla. Ndị ode akwụkwọ kwenyere na enwere ike ịkwụsị mgbasa nke usoro mkpali na anụ ahụ retroperitoneal site na ntinye nke mmiri na ọgwụ n’otu oge n’ime akwara abụọ.

V.P. Grigoriev (1978) maka iwebata ndị na - egbochi inyocha catheterized gland kwesịrị ekwesị. Uru nke akpọrọ nchịkwa nke ndị na - egbochi mgbochi bụ nke a, na mgbakwunye na usoro a na-ahụ maka pancreas, ọ na - enye gị ohere ịgafe ihe nzacha nke ndu - imeju na ngụgụ.

N'ime usoro ọgwụgwọ, ejirila ndị na-egbochi nchebe mee ihe maka ebumnuche akụ na ụba, yana n'ihi enweghị ike na mkpocha akwara. Agbanyeghị na toxemia siri ike, ọgwụgwọ ejikọtara ya na cytostatics na protease inhibitors bụ ihe amamihe dị na ya, nke ga - enye gị ohere igbochi usoro na gland n'onwe ya ma mee ka enzymes na - agagharị n'ọbara, nymph, na anụ ahụ.

Ọgwụ ọria pancreatitis

Okwesiri iburu n’uche na nnukwu oria a na-ekwu maka ọnọdụ ọsịsọ, a na-emekwa ọgwụgwọ ya naanị n’ụlọ ọgwụ, ebe a na-ebute ndị ọrịa mberede site n’ụlọ ọrụ mberede. N'okwu ndị siri ike, nke na-eme na 20-25% nke ndị ọrịa, enwere ike ịhụ ọnọdụ dị n'akụkụ ure mgbu azụ, yana enwere oke mmụba n'ihi ọgbụgbọ, na hypovolemia.

Ya mere, ọgwụ maka nnukwu pancreatitis, na mbụ, kwesịrị belata nnukwu ihe mgbu, yana ọgbụgbọ, vomiting, ọnụego obi na-abawanye na mbelata ọbara mgbali, yana iweghachi nguzo mmiri-electrolyte na ahụ. A na-ewepụta ihe mgbu site na nchịkwa parenteral nke analgesics (Novocaine nwere glucose, Analgin, Ketanov) ma ọ bụ ọgwụ antispasmodics: No-shpa, Papaverine hydrochloride, Platifillin hydroartate, Metacin ma ọ bụ Ganglefen hydrochloride.

N'otu oge ahụ, a na-eme mgbake mmiri na nkwụghachi nke akwara: a na-etinye dropper ugboro ugboro maka pancreatitis - nke nwere nnu, glucose na ihe ndị ọzọ na-akwado ọrụ nke sistemu na akụkụ dị iche iche. Ọrịa nkwarụ sitere na sistemụ mkpali, sepsis na otutu akwara na - etolite n'ime ndị ọrịa nwere nnukwu ọrịa pancreatitis n'ihi eziokwu ahụ bụ na enzymes na - eme ka pancreatic enzymes na - agbari membranes nke mkpụrụ ndụ nke ya.

Ya mere, a na-ejikọkwa usoro nlekọta siri ike na mgbochi nke ọrịa nke anụ ahụ na-emetụta ya ma ọ bụ ọgụ megide ọrịa nje na-adị, a na-ejikwa ọgwụ nje na gastroenterology iji dozie nsogbu a (oge kachasị, nke a bụ Amoxiclav ma ọ bụ cephalosporins nke atọ). Na njirimara nke iji ha na gastroenterology, lee - Ọrịa pancreatitis na-efe efe na ụmụaka

Ọrụ ọzọ bụ ịkwụsịlata ọrụ nzuzo nke gland iji ghara nanị ịmachi ibu ya ruo ókè o kwere mee, kamakwa iji kwụsị mbibi a na-apụghị ịgbagha agbagha nke mkpụrụ ndụ, na-eduga na pancreatic necrosis. Maka nke a, enwere ọgwụ ndị na-egbochi njikọ nke enzymes pancreatic. Aha ha:

• Aprotinin (okwu - Kontrikal, Gordoks, Traskolan),
• Octreotide (Octrid, Octretex, Sandostatin, Seraxtal).

Dịka iwu, a na-eji ha maka nnukwu pancreatitis na okenye. Gụkwuo banyere ha n’okpuru.

Ọgwụ maka pancreatitis na-adịghị ala ala

Isi ihe kachasị mkpa, nke gụnyere usoro ọgwụgwọ maka ọrịa ọgwụ pancreatitis na ọgwụ, bụ igbochi ọrụ nke pancreas, ya bụ, belata mmepụta nke enzyme ya. Ọ bụ ihe a nabatara na mkpụrụ ndụ gland parenchyma na-emebi site na nchekwa nke ya na ya mebiri, a na - amalite imebi ihe na mkpụrụ ndụ acinar mgbe intracellular bidoro ọrụ nke enzymes diges.

Na ụdị ọrịa ahụ na-adịghị ala ala, enwere ike iji Pirenzepine (Gastrocepin) ma ọ bụ Profinia bromide (Riabal) iji belata mmepụta enzymes proteolytic. Edere ọgwụ ndị a maka iwe ọrịa pancreatitis: ọ bụrụ na e bute onye ọrịa n'ụlọ ọgwụ, a na-eji Pirenzepine eme parenterally.

Ọnọdụ nke erughi nke enzymes nri ihe mgbu na-esonyere ọnya na-adịghị ala ala yana mmebi nke mkpụrụ ndụ na akwara. Iji kpuchie ya, ndị na-ahụ maka gastroenterologists na-edepụta nhazi enzyme nwere protein (nke na-ekewa), amylase (maka hydrolysis nke carbohydrates dị mgbagwoju anya) na lipase (nke mere na anụ ahụ nwere ike ịmịkọrọ abụba). Ndị a gụnyere Pancreatin, nke nwere ọtụtụ aha azụmaahịa: Pancitrate, Pangrol, Pancreasim, Penzital, Mikrazim, Creon, Mezim, Gastenorm forte, Vestal, Hermitage, wdg Na mgbakwunye na pancreatitis, ihe ngosi maka iji enzymes gụnyere nsogbu na usoro digestive nke etiologies dị iche iche, dyspepsia. , flatulence, fiystrosis cystic, njehie nke ihe oriri.

Iji gbochie mmepụta hydrochloric acid na afọ, ụba ọrụ nke na-eme ka njikọta ihe ọ pancụ pancụ pancreatic jupụta na usoro ọgwụgwọ. mgbu na-adịghị ala ala ewebata ogwu nke otu uzo ogwu ato ozo:

• antisecretory H2 antihistamines: Ranitidine (Ranigast, Atzilok, Zantak, wdg) ma ọ bụ Famotidine (Pepsidin, Kvamatel, Gastrosidin),
• ndị na - egbochi enzyme hydrogen-potassium ATPase (proton pump): Omeprzazol (Omez, Gastrozole, Promez), Rabeprazole ma ọ bụ Lansoprol (Lanzol, Clatinol, wdg),
• antacids na alumini na magnesium hydroxides - Almagel (Alumag, Gastratsid, Maaloks), nke na - egbochi acid n’ime afọ.

A kọwara usoro nke ihe, ụdị mwepụta, usoro nke ihe na dose na ọgwụ ndị ọzọ nke ọgwụ ọgwụ ndị a ka akọwapụtara n'ụzọ zuru ezu Ọbara afọ

Banyere ọgwụ ndị a chọrọ maka ọrịa ọrịa pancreatitis na ụmụaka, yana gbasara atụmatụ ha si eji nwata, gụọ akwụkwọ - Ọgwụ nke pancreatitis na-adịghị ala ala

A na-atụle ọgwụ maka pancreatitis, nke na-egbochi mmepụta enzyme nke pancreatic (Aprotinin, Octreotide, Pirenzepine, Prifiny bromide) ma mejupụta maka erughi ha nke mechara pụta (Pancreatin), ka a tụlere n'ụzọ zuru ezu n'okpuru.

Ojiji nke ndị na - egbochi ihe na - egbochi ihe ọria

Na pancreatitis, mmegharị nke nchebe na-eduga na mbufụt nke anụ ahụ yana mmepe nke saịtị necrotic.

Iji gbochie usoro ọgwụgwọ dị otú a, ọkachamara ahụ na-edepụta Mgbakọ, Trasilol, Gordoks ma ọ bụ Antagozan. Ojiji nke ọgwụ ndị a maka nchịkwa intraven dị mkpa n’ụbọchị mbụ nke nnukwu pancreatitis.

Endị enzymes pancreatic

Isi ọrụ nke pancreas bụ ịrụ ọrụ endocrine (nke ime) na exocrine (mpụga). Ọrụ endocrine gụnyere mmepụta nke homonụ - insulin, nke na-ebelata glucose, na glucagon, nke na-atụnye ụtụ n'inye glucose na umeji.

Ọrụ exocrine nke pancreas bụ imepụta enzymes pụrụ iche (enzymes) maka nri. Ha kwesiri ka ekee ha n’otu n’otu - lipolytic, amylolytic na enzymes proteolytic. Ka anyị tulee n'ụzọ zuru ezu akụkụ nke ọ bụla.

Enzymes Lipolytic. Otu a nwere ọrụ maka mmebi nke abụba abụba na glycerol. Prolipase bụ enzyme lipase na - adịghị arụ ọrụ nke, mgbe ọ banyere duodenum, na - ejikọ ya na colipase.

Lipase na-eme ka enwee salts na trypsin zuru oke. A na-emebisị ihe ndị dị na lipolytic n'ime awa 7-14. Renal glomeruli na-ahụ maka ịkpụcha ha: ha na-akwalite nnabata nke lipase na nhazi anụ ahụ, ya mere, a chọpụtaghị irighiri mmiri nke mmịkọ na mmamịrị. A na - emepụtakwa ihe ndị dị ka lipase site na imeju, akpa ume na eriri afọ.

Enzymes amylolytic. E nwere ọtụtụ ụdị - alfa, beta na gamma amylase.A na-akpọkwa enzymes ndị a sitị. Na usoro mgbaze, ọ bụ naanị alfa-amylase esonye.

A na -emepụtakwa ya na obere ego site na gland dị iche iche, karịsịa mgbe a na-ata ata. Yabụ, anyị na-enwe mmetụta dị ụtọ mgbe anyị na-ata ata nri dị iche iche - osikapa ma ọ bụ nduku. Site na amylase, usoro nke iwelata stachi na carbohydrates ndị ọzọ siri ike na-adị mfe.

Enzymes nke Proteolytic. Ọrụ bụ isi otu a bụ ndọkpụ nke protein. Enzymes nke Proteolytic na-eso akpata mmebi nke amino asịd dị na peptides na protein. E nwere ụdị nchebe abụọ dị iche iche na mmiri ihe ọ juiceụ pancụ:

1. Peptidase, ma ọ bụ exopeptidase, na-ahụ maka hydrolysis nke ogige mpụga nke peptides.
2. Proteinase, ma ọ bụ endopeptidase, nke na-akụda ihe dị n’ime peptides.

N'ihi ya, lipase, amylase na protease na-emejupụta mmiri ọgwụ areatụ, nke, mgbe ọ na-abanye duodenum, na-agbajikwa ụmụ irighiri ihe nri ndị dị mgbagwoju anya ka ha dịrị nfe.

Ihe na-akpata ya na ihe mgbaàmà nke pancreatitis

N'ime ahụike, ịgbalite enzymes pancreatic na-apụta na duodenum.

Ọ bụrụ na arụ ọrụ nke amylase, proteinase na lipase na-amalite na pancreas n'onwe ya, anyị nwere ike ikwu maka ọdịda nke akụkụ ahụ.

Aghọtara Pancreatitis dị ka ihe mgbagwoju anya nke syndromes na ọrịa ndị na-esite na mmezi nke enzymes na gland, nke na-eduga usoro "mgbaze onwe". N'ihi ya, ha anaghị abanye duodenum ahụ, nri digestion na-ama jijiji.

E nwere ọtụtụ ihe na-eduga ụdị usoro a:

• ị drinkingụ mmanya ugboro ugboro
• ịhapụ iso nri ziri ezi,
• oke oriri nke nri eghe na nke abuba,
• iri nri na-edozi ahụ riri oke nri ma ọ bụ buo ọnụ,
• Nchịkwa ọgwụ ụfọdụ n’agaghị achịkwa
• mmerụ nri usoro
• pathology nke ọrịa.

Site na mmegharị nke enzymes na pancreas, mbufụt na-eme: ọ na-abawanye na nha, mpaghara necrotic na-apụta. Usoro dị otú a enweghị ike ịbụ asymptomatic, na mgbakwunye, enwere mmebi nke eriri afọ.

Site na enweghi ntụpọ nke enzymes pancreatic na duodenum na mbufụt nke pancreas, a na-ahụ ihe mgbaàmà ndị a:

1. Mgbu na hypochondrium nke aka ekpe, mgbe mgbe ọ na-eme ọrịre.
2. Nnukwu mbelata nkwarụ, ọrịa na adịghị ike.
3. Ọrịa dyspeptik - ịmịcha ọbara ọgbụgba, ọgbụgbọ ma ọ bụ ọgbụgbọ, enweghị agụụ, nri ụra.

Ihe mgbaàmà nke ọrịa ahụ nwere ike ịdị iche na-adabere na enweghị enzyme otu:

• Enweghị Amylase na-ebute afọ ọsịsa, ụkọ vitamin, oke ịbelata oke. Ahụ ọkụ na-aghọ mmiri, ihe oriri na-esighi ike dị na ya.
• Enweghi oke nke lipase nke na-akụda abụba na-akpata steatorrhea - mmụba na ụba nke abụba dị na oche. Site na otite, ọnya na-acha odo odo ma ọ bụ oroma, a na-ahụ ihe dị n'ime mmiri.
• Site na ụkọ protin, a na-ahụ eriri protein nke na-enweghị ihe ọ bụla. Ihe njiri mara ya bu nmeghari akwara.

Ọ bụrụ na mmadụ achọpụta ihe ịrịba ama ndị ahụ, ọ kwesịrị ịchọ enyemaka ahụike ozugbo enwere ike. Dọkịta ga-edenye ụzọ maka nnwale na ọgwụgwọ zuru oke.

Nkịtị Enzyme Enzyme Na-egbochi

Ahụ́ mmadụ na - emepụta ọ bụghị naanị enzymatic ihe na - enyere aka nbibi nke ụmụ irighiri ihe dị mgbagwoju anya, kamakwa ndị na - egbochi ihe nzuzo na - egbochi. ihe ndị na - egbochi oke mmiri ihe ọ pancụ pancụ pancreatic.

Ndị na - egbochi enzyme gụnyere ọgwụ ndị a na - eme ka ọ bụrụ polypeptide pancreatic (PPP), YY peptide, somatostatin, glucagon pancreatic, pancreastatin na neuropeptides.

Agwaetiti Langerhans, nke kachasị na ọdụ nke pancreas, na-emepụta hormone pụrụ iche, PPP, nke na-egbochi mmepụta mmiri, enzymes na bicarbonates. Ọ na - egbochi mmepụta nke acetylcholine.

Usoro nzuzo PPP na-abawanye n'ụdị ndị a:

1. inye nri ma ọ bụ iri nri,
2. site na mkpali nke irighiri akwara,
3. na duodenal acidification,
4. Mgbe ekpughere ya na gastrin na-ewepu peptide,
5. mgbe ekpughere ya na nzuzo, cholecystokinin na VIP.

Umlọ ahụ na colon distal na-ahapụ YY peptide ozugbo abụba batara na mgbaze. Peptide a na - enyere aka belata ike nke gland na nsonaazụ cholecystokinin na nzuzo.

Mkpụrụ ndụ Pancreatic D na akpụkpọ ahụ mucous nke diges na-emepụta somatostatin. Homonụ a na - egbochi mmepụta nke enzymes na bicarbonates. Sistem na akwara autonomic na-ekere òkè na mmepụta nke somatostatin, ozugbo abụba na amino asịd sitere na nri.

Ndị ọzọ na-egbochi ọgwụ mgbochi na-anọchi anya homonụ ndị dị otú a:

• Pancreatic glucagon, nke na-akwụsị imepụta mmiri, bicarbonates na enzymes.
• Pancreastatin, na-egbochi ịhapụ acetylcholine. A na-emepụta ya na ngwụcha njedebe nke akwara ahụ.
• Neuropeptides, nke mejupụtara calcitonin-information peptide (na-akpali somatostatin) na enkephalins (belata mmepụta acetylcholine).

Site na usoro ndị na-emebi emebi na gland, enwere ike ịmechi ihe nzuzo nke pancreatic enzyme inhibitors, yabụ ị ga-a medicationsụ ọgwụ.

Cipleskpụrụ nke ọgwụgwọ maka ọrịa anụahụ

Ihe abuo abuo nke ezigbo ọgwụgwọ maka oria a bu nri nri na ogwu. Usoro ọgwụgwọ a na-ewulite n'otu n'otu dabere ogo ọrịa ahụ na mmebi ahụ.

Ihe oriri pụrụ iche maka ọrịa anụ ezi sitere na nri Nke 5 dị ka Pevzner. Ọ na-ewepụ oke nri nke carbohydrate na abụba oriri, ma na-ezubekwa iri nri protein.

Site na mmalite nke ọrịa pancreatitis na-adịghị ala ala, a na-edenye ụbọchị 3-4 nke ibu ọnụ. N'oge a, ị ga-ajụrịrị iri nri na ị drinkụ mmiri alkaline dị ọkụ, dịka ọmụmaatụ, Borjomi.

Agụụ na-egbu ya mgbu, a na-ewebata nri ndị dị na nri nke na-agaghị agbari nri nri. A na-ahapụ ndị ọrịa na-arịa ọrịa pancreatitis:

• ụdị anụ na azụ, ụdị nri dị iche iche.
• ofe akwukwo nri na ahihia kpọrọ nkụ,
• Achịcha na achịcha ụnyaahụ,
• skim mmiri ara ehi,
• nkpuru osisi, ahihia na akwukwo nri.
• ọka a gbanyere n'ime mmiri ma ọ bụ mmiri ara ehi na-enweghị abụba.
• na àkwá kechara ọtụtụ,
• efere rosehip, mmanụ a honeyụ ma ọ bụ jam (amachaghị).

Site na mbufụt nke pancreas, ọ dị mkpa ịjụ nri na-eme ka usoro digestive ka njọ:

1. Ngwa ahịa chọkọleti, achịcha, kuki.
2. Achịcha ọhụrụ.
3. Ihe oriri.
4. Ichebe ya, smut meats na pickles.
5. Anụ oriri na azụ̀ nwere abụba.
6. Ngwaahịa mmiri ara ehi.
7. Ihe ọ .ụ .ụ Carbonated.
8. Ngwa nri.
9. Ọkpụkọ ọgaranya.
10. E nwere ọtụtụ àkwá.
11. Tii siri ike na kọfị.
12. Ngwa soseji.
13. Legumes na tomato.

Site na mkpo obi nke pancreatitis na-adịghị ala ala, ọ dị mkpa ịgbaso ezumike ụra.

Ọgwụ maka pancreas gụnyere ihe:

• enzyme inhibitors iji belata rụọ ọrụ nke pancreatic proteases (proteinases),
• ihe ndị na - egbochi ihe na - egbochi ọnya afọ nke oghere nwa, purulent mbufụt nke nkwanye bursa, mmepe nke necrosis na ịtụgharị cellulite cellulose nke oghere n'azụ peritoneum
• Ihe mgbochi H2 iji belata mmepụta hydrochloric acid,
• ọgwụ mgbochi na-egbochi mmiri hydrochloric acid n'ime eriri afọ,
• antispasmodics maka nkwarụ nke akwara dị mma nke metụtara ọrụ sphincter arụ ọrụ na nsị akwara,
• ọgwụ anticholinergic iji gbochie usoro ndị na-adịghị ahụkebe na ganglia na cobex cerebral,

Na mgbakwunye, a na-eji ndị enzymatic mee ihe iji melite usoro mgbaze ma kpochapụ ọgba aghara dyspeptik.

Ọgwụ dị irè

N'ụbọchị mbụ nke iwe nke ụdị na-adịghị ala ala, ojiji nke mgbochi inhibitors maka ọgwụgwọ nke pancreatitis dị mkpa. Ọgwụ ndị a na - ewepụ ihe kpatara ọdịdị nke mgbu azụ na mgbasa nke saịtị necrotic.

A na-enweta ọgwụ site na pulmonary parenchyma na ehi pancreas.

N'okpuru ebe a bụ ọgwụ kachasị dị irè, usoro ọgwụgwọ nke ọgwụ dibịa na-ekpebi n'otu n'otu. Ha adịghị n'ụdị mbadamba, mana n'ụdị itinye uche ma ọ bụ lyophilisate maka infusion.

A na-eme ọgwụgwọ nke pancreatitis na inhibitors na nlekọta intravenous naanị na ọnọdụ supine. Ọzọkwa, nọọsụ na dọkịta kwesịrị iji nlezianya nyochaa ọnọdụ onye ọrịa. Diet Nke 5, nke ya na usoro ogwu kwesiri ijikwa na mgbake onye ọrịa n’enweghi nsogbu, aghaghi ileba ya anya nke ọma.

Otu esi agwọ ọrịa pancreatitis ga-agwa ndị ọkachamara na vidiyo n'isiokwu a.