Ihe kachasị dị mkpa nke ọgwụ ahụ bụ antioxidant endogenous.

Thioctic acid belata ogo nke glucose n’ime ọbara, na-enyere aka imeri nguzogide insulin, na-emekwa ka ihe glycogen na-abawanye na imeju. Ọ bụ ụdị okike na vitamin nke otu B. Ọ na-ekere òkè na oke ume na carbohydrate, na-eme ka ọrụ imeju na-arụ ọrụ, na-arụ ọrụ metabolism. cholesterol.

Na mgbakwunye, thioctic acid na-arụ ọrụ dị ka hepatoprotective, hypocholesterolemic, ịbelata ike na hypoglycemic pụtara. Ọ na-eme ka ọ nwee iko ọfụma neuronsna-ebelata ngosipụta nke mmanya na ọrịa shuga polyneuropathyrụọ ọrụ axonal ije.

Ntinye uche maka nkwadebe nke ihe ngwọta ya na nchịkwa ihe dị n'ime esighi n'oche 25-38 μg / ml. Olu nke nkesa dị ihe dịka 450 ml / n'arọ.

Capsules na mbadamba mgbe a na -ekwu ya n’okwu na-etinye oge na obere oge. Ọ bụrụ na ejiri nri rie ya, ọ na-ebelata mmịkọ. Bioavailability bụ 30-60%. Oke ruru n'ọbara na erute na nkeji 25-60.

N'agbanyeghị ụdị usoro onunu ogwu, a na-edozi ọgwụ ahụ na imeju site na conjugation na oxidation nke eriri akụkụ. Ọ bụpịrị ihe akụrụ ya dịka ihe dịka 80-90%. Oge iwepụ ọkara ndụ bụ nkeji iri abụọ na ise.

Ihe ngosi maka iji Oktolipen

Ihe na-egosi maka iji Oktolipen n'ụdị capsules nke 300 na 600 mg:

• polyneuropathy nke ọrịa mamịrị,
• polyneuropathy nke sitere na ịholicụbiga mmanya ókè.

Ihe ngosiputa maka iji Oktolipen na uzo nke uzo maka infusion nke 12 na 25 mg:

Nsonaazụ

Mgbe ị na-eji ọgwụ a, nsonaazụ ndị a nwere ike ime:

• anya nke mmeghachi omume nfụkasị ahụ (ọbụlagodi ihe atụ anaphylactic kwere omume)
• site na ngwe nri ọgbụgbọ, obi mgbawa, vomiting,
• mgbaàmà hypoglycemia.

Oktolipen - Ntụziaka maka ojiji

Maka ndị enyere ọgwụ mọstul Octenipen ma ọ bụ mbadamba nkume, ntuziaka maka ojiji gụnyere ị useụ ọgwụ kwa ụbọchị n'ụtụtụ na afọ na-enweghị isi ọkara otu awa tupu eri. Oge nri n’otu oge na-ebelata oke ịgwọ ọrịa ọgwụ. A naghị atụ aro ịta na ịta nri na mbadamba ụrọ.

Ọgwụ kwa ụbọchị, nke na-enye ntuziaka maka ojiji nke Oktolipen - 600 mg (1 mbadamba ma ọ bụ capsules abụọ). Agbanyeghị, dọkịta kpebiri na oge ole ihe a ga-eme ya na usoro ọgwụgwọ ikpeazụ ya bụ dọkịta.

Iji mee ka ịdị mma nke ọgwụ dịkwuo mma na oge ụfọdụ, etinyere izu mbụ nke 2-4 ka eji ntinye uche maka nkwadebe nke infusus, emesia eji capsules ma ọ bụ mbadamba na ọkọlọtọ ọkọlọtọ.

Iji kwadebe ihe ngwọta, a na-eji 1-2 ampoules mee ihe, nke a na-agwakọta na 50-250 ml nke slorum chloride 0.9%. Mgbe emechara nkwadebe, a na-ahụ ya n'usoro. Ọkọlọtọ bụ 300-600 mg kwa ụbọchị.

Ọgwụ nwere mmetụta dị nro na ọkụ, yabụ, a ga-ewepụ ampoules naanị ozugbo tupu ojiji. N'oge a, ọ dịkwa mma iji chebe vial site na ìhè anyanwụ. Ekwesịrị ịchekwa azịza a kwadebere ebe echekwara nke ọma site n'ìhè, ọ gaghịkwa awa 6 ka emechara nkwadebe.

Mmekorita

Ọgwụ na-akpali mmetụta hypoglycemic insulin na ọgwụ antidiabetic na-ewere n'ọnụ. Ọ bụ ya mere, mgbe ị na-ejikọ ọgwụ ndị a, ịkwesịrị ilebara ọdịnaya glucose plasma anya mgbe niile ma dozie usoro nke ọgwụ antidiabetic ma ọ bụrụ na ọ dị mkpa.

Na mgbakwunye, ị kwesịrị ị na-elele oge ọkara ahụ dị n'etiti iwere Oktolipen na ngwaahịa mmiri ara ehi, yana nkwadebe na iron, calcium na magnesium. N'okwu a, ọ ga-adị mma ka ị were Oktolipen n'ụtụtụ, ma nwee iron, magnesium na calcium na mgbede. Na mgbakwunye, ọgwụ a na-ebelata mmetụta. cisplatin na-eji otu oge.

Effectivedị arụ nke Oktolipen n’onwe ya na-ebelata mmanya ethyl. Yabụ na n'oge ọgwụ a, a na-atụ aro ka ọ hapụ ị drinkingụ mmanya.

Thioctic acid na-emekwa ka ihe mgbochi nke ọgụ na-arụ ọrụ ọgwụ glucocorticosteroid.

Nyocha banyere Oktolipen

Nyocha banyere Oktolipen na-abụkarị nke dị mma. Ọtụtụ ndị ọrịa na-achọpụta ịdị ike ya. Mgbe ụfọdụ a na-enye ya n’ụlọ ahịa ọgwụ n’ọnọdụ dị oke ọnụ karịa Izu ahihia. Nyocha banyere Oktolipen n'otu oge ahụ na-ekwu na nsonaazụ nke ọgwụ ahụ dị ka analogue ya.

Nchikota kwa mbadamba

Ngwakọta ọrụ na-arụ ọrụ, acid thioctic (ct-lipoic acid) - 600.0 mg. Ndị e mere:

isi: hyprolose dị ala (obere ntụgharị hydroxypropyl cellulose) -108.880 mg, hyprolose (hydroxypropyl cellulose) 28.040 mg. croscarmellose (croscarmellose sodium) - 24.030 mg, colloidal silicon dioxide - 20.025 mg, magnesium stearate - 20.025 mg,

shei: Opadry edo edo (OPADRY 03F220017 Yellow) - 28,000 mg nke hypromellose (hydroxypropyl methylcellulose) - 15.800 mg, macrogol-6000 (polyethylene glycol 6000) -4.701 mg, titanium dioxide - 5.270 mg, talc - 2.019 mg, quinoline ọla edo (quinoline 104) - 0.162 mg, iron dye oxide odo (E 172) - 0.048 mg.

Mbadamba ụrọ nwere ihe mkpuchi fim site na odo na-acha odo odo ruo odo, oval, biconvex nwere ihe ize ndụ n'otu akụkụ. Na kink si ìhè edo edo ruo odo.

Ngwongwo ogwu

A na-ahụ acid Thioctic (a-lipoic acid) n’ahụ mmadụ, ebe ọ na-arụ ọrụ dị ka coenzyme na phoidọsị oxidative nke pyruvic acid na alpha-keto acid. Thioctic acid bụ antioxidant endogenous. Thioctic acid na-enyere aka ichebe mkpụrụ ndụ site na nsonaazụ nsonaazụ nke radicals na-apụta na usoro metabolic, na-egbochi oke mmiri ọgwụ ọjọọ. Acid Thioctic na-eme ka ịba ụba nke endogenous antioxidant glutathione, nke na-eduga n'ịbelata ogo ihe mgbaàmà nke polyneuropathy. Ọgwụ nwere hepatoprotective. hypoliplera, hypocholesterolemic, mmetụta hypoglycemic, na-eme ka neurons trophic dịkwuo mma. Ihe mmekọrịta nke thioctic acid na insulin na-ebute na ịba ụba glucose. Mlọ ọgwụ

Mgbe a na -ekwu ya n’onu, ọ na-ewepu ngwa ngwa na ngwangwa ahụ site na eriri afọ, ịbịnye nri na nri nwere ike belata mmịnye ọgwụ ahụ. Theụ ọgwụ ahụ, dịka ndụmọdụ ndị a tụrụ aro si dị, nkeji iri atọ tupu iri nri agaghị enye gị ohere iso nri, ebe ọ bụ na emechaala ihe oriri thioctic acid n'oge iri nri. Oke ntụpọ nke thioctic acid na plasma ọbara ruru 30 nkeji mgbe ị theụsịrị ọgwụ ahụ wee bụrụ 4 /g / ml. Thioctic acid nwere “mbu ụzọ” sitere na imeju. Ezigbo bioavailability nke thioctic acid bụ 20%. Metabolzọ metabolic bụ ụzọ dị mkpa bụ oxidation na conjugation. Ọkpụkpụ nke Thioctic acid na metabolites ya na-apụta site na akụrụ (80-90%). Ọkara ndụ (T1 / 2) bụ nkeji iri abụọ na ise.

Jiri n’oge ime na n’oge a na-enye nwa ara

Ihe ogwu ahu n'oge ime anakwo na ezighi ezi ulo ogwu na thioctic acid n’oge di ime. Ihe omumu banyere ihe omimi banyere omumu amuputaghi ihe egwu di na omumu, ihe ndi n’eme na mmepe nwa ebu n’azu na ihe ogwu ndi n’eme ya.

Ogwu Oktolipen na-a duringụ ara n’oge a na-a isụ ara na-egbochi imebi data n’arịrị nke thioctic acid n’ime mmiri ara.

Usoro onunu ogwu na nhazi

Usoro a tụrụ aro bụ 1 mbadamba (600 mg) otu ugboro n'ụbọchị. A na-eji ọgwụ a na -e oomi ọgwụ, na afọ efu, nkeji 30 tupu nri ụtụtụ, na-enweghị atụ, jiri mmiri sachaa ya.

N’ime nsogbu nke onwe, nke siri ike, ọgwụgwọ malitere site na nhọpụta ọgwụ Okolipen intravenous solution maka izu iri abụọ na anọ, wee gafee n’ọnụ ọgwụ ọgwụ Okolipen® (usoro ntụgharị). Dọkịta ga-ekpebi ụdị oge ọ ga-eji agwọ ọrịa.

Ngwakọta, nchekwa na ọnọdụ ire ere

Ọ dị na otu n'ime ụzọ atọ ga - ekwe omume: mbadamba nkume, kapịnụ ma ọ bụ ampoule nwere oke iji kwado maka ụzọ edozi ndị na - akwatu ya.

A na - eji ihe inyeaka: na mbadamba - calcium hydroorthophosphate (ọcha ma ọ bụ enweghị kristal), magnesium stearate (ezigbo nkewa ntụ ntụ na - acha ọcha) yana titanium oxide - agba ọcha. Na capsules, a na-eji ihe dịtụ iche nke na-enye ihe eji edozi mmiri - gelatin, nkwụchi nke colloidal nke silicon oxide, yana agba edo edo abụọ: quinoline odo na "ọdịda anyanwụ" (E 104 na 110, n'otu n'otu). A na - enweta ọgwụ ampoules nwere oke zuru ezu yana ihe mgbaze site na ngwakọta nke mmiri mmiri na - etinye obi ya na nnu mmiri EDTA.

Iji ọgwụ ọjọọ eme ihe

O nwere ndepụta dị mma na ahụ. Otu n'ime ha:

• Neuroprotective - nchedo sel akwara, tinyere mkpụrụ ndụ ụbụrụ, site na mmetụta ọjọọ nke ọrịa ụfọdụ na nsí. Na-enye aka belata mmetụta ọjọọ nke nsị neurotoxin. Mmụba axonal arụ ọrụ na trophic neurons.
• Hypoglycemic - mbelata nke ọbara shuga. Ọ nwere ike inyere ndị ọrịa nwere ọrịa shuga ọgwụ nwere mgbagwoju anya n'ihe banyere polyneuropathy. Jiri ịkpachara anya na ndị mmadụ ozugbo ị insụsịrị insulin ma ọ bụ ndị mmadụ na-arụ ọrụ oke.
• Hypocholesterolemic - na - ebute mbelata nke cholesterol ọbara, yabụ, a na - a drugụ ọgwụ a maka ọrịa imeju, mmebi abụba na ọrịa imeju ndị ọzọ.
• Hepatoprotective - ọgwụ a na - eme ka ike gwụ ma ọ bụ na - ewepụ ihe pathogenic na imeju, nke na - agbanwe na ọnwụ. A na-ewere ya dị ka akụkụ nke usoro ọgwụgwọ siri ike maka ịba ọcha n'anya, na-ebelata oge ọ na-arịa ọrịa na ịkwụsịlata ihe ọdịdọ.
• HypolipPs - usoro iji belata ogo nke lipids n'ime ọbara, na-ebelata ihe ize ndụ nke oghere atherosclerotic na mgbidi arịa.

A kwenyere na thioctic acid bụ antioxidant dị ike dị n'ime nke na-eme ka ọ bụrụ naanị mgbe ọ gafesịrị usoro nri.

Alfa-lipoic acid na-agbadata mkpocha shuga n'ime ọbara ma na-emeri mmetụta nke nguzogide insulin. Site na ịbawanye ogo nke glucose na ahụ, ọ na-enye aka na mmụba nke nkwanye ugwu glycogen na anụ ahụ. Site na akụrụngwa ya, thioctic acid yiri vitamin B, na-ekere òkè na shuga na abụba metabolism n'ime ahụ, n'ihi ntụgharị nke cholesterol ka ọ bụrụ usoro ọmụmụ nke adịghị emerụ ahụ (cholesterol metabolism) na-eme ka arụ ọrụ nke gland hepatic na-arụ ọrụ.

A na - etinye ihe dị n'ọrụ sitere na mbadamba nkume na ihe mkpuchi na - abanye n'ọbara ngwa ngwa, mana a ga - echeta na nchịkwa oge nke ọgwụ na nri na - eme ka ịnakwere akụkụ nke ọgwụ ahụ. A na-ahụkarị nsị anụ ahụ kacha elu n'ime nkeji iri atọ ruo iri atọ na ise mgbe mmachara ahụ.

N'agbanyeghị ụdị nchịkwa (ọnụ ma ọ bụ infusion), Oktolipen 600 na-ahazi ya na imeju ma na-eme ya site na akụrụ ya ihe fọrọ nke nta ka ọ bụrụ kpam kpam - ọ dịghị ihe karịrị pasent iri na-adịgide n'ime ahụ mgbe ọkara ndụ abụọ gasịrị - nkeji iri asaa.

Ihe ngbanwe

Ọgwụ "Oktolipen 600", analogues na ihe ndị ọzọ yiri ya site na otu ọgwụ ọgwụ ndị ọzọ nwere obere contraindications. Ihe a na-enye nkwekọrịta contraindications anọ na - abụghị ọkachamara:

• Ọnụnọ nke hypersensitivity na-arụsi ọrụ ike na ọgwụ, obere mgbe - ka nso mmiri.
• Oge ime.
• Mmiri ara ehi nye nwa.
• Mụaka gbara afọ isii.

Nsonaazụ

Ọgwụ "Oktolipen 600" nwere mmetụta dị iche iche dị ịtụnanya, mana a naghị atụle ihe ka ọtụtụ n'ime ha, ebe ọ bụ na mmeghachi omume ndị dị otú ahụ na-erughị obere na otu narị puku mmadụ. Kacha nkịtị n’ime ha gụnyere:

• Mmeghachi omume nfụkasị (site na obere urticaria na / ma ọ bụ itching na saịtị nke ịkpọtụrụ ọgwụ ahụ na mucosa na edema nke akụkụ okuku ume na ujo anaphylactic).
• A naghị ahụkarị nsonaazụ na akwara afọ, gụnyere ọgbụgbọ, ọkụ na afọ, na ọgbụgbọ.
• Ihe a na-ahụkarị bụ ihe mgbaàmà nke shuga dị ala (hypoglycemia): ike ọgwụgwụ, dizzness, iro ụra - agbanyeghị, a na-ewepụ ha nke ọma site na ị aụ teaspoon shuga.

Iwu nnabata

"Otu esi ewere Oktolipen 600?" Ọtụtụ ndị na-azụ ahịa na-ajụ. Ndị ọrịa edepụtara maka ọgwụ "Oktolipen 600" kwesịrị ịhereomi nnabata ndị a: a na-ewere otu mbadamba ọkara ọkara tupu nri na afọ efu (teta - rankụọ ọgwụ - na-echere - rie).

A na-enye otu milligramms kwa ụbọchị 600 ọgwụ: otu mbadamba ma ọ bụ abụọ. N'otu oge, oge nchịkwa na usoro ị doụ ọgwụ ahụ ka dị n'aka dọkịta, a ga-agbanwe ya dabere na ọrịa ahụ.

Iji mee ka uru ọ bụla dị n’obere ndị ọrịa siri ike, a na-edenye ọgwụ ahụ n’otu oge ihe dị ka izu atọ. Mgbe ahụ, ka oge a gachara, a na-ebugharị onye ọrịa ahụ na usoro ọgwụgwọ: otu mbadamba kwa ụbọchị.

Maka nchịkwa site na igwe eji agwo mmiri, a na-akwado nkwadebe ahụ dịka teknụzụ ndị a: ọdịnaya nke otu ma ọ bụ abụọ Octolipen 600 ampoules na-agbaze na nha (site na 50 ruo 250 milliliters) nke salio physiological - ruru sodium chloride na mkpokọta nke ngwakọta bụ 0.9 pasent. A na-eri nri nke diluted, na-abụkarị n'ime awa abụọ, iwebata anụ ahụ na-ebu intravenly site na dropper. Adị ọgwụ dị otú a maka ọgwụ infusion na-enye gị ohere ịbanye n’arụ onye ọrịa site na narị milligrams nke narị atọ na narị isii nke ọgwụ "Oktolipen 600".

Ntụziaka maka ojiji, ọnụahịa - ihe ndị a niile chọrọ iji nlezianya jiri ọgwụ ahụ. Ọgwụ nwere mmerụ ahụ na-abawanye n'ihe omume anwụ, yabụ, a ga-emeghe ampoules nke itinye uche ozugbo tupu ejiri ya. Ọzọkwa, ọbụna ọgwụ gbara alụkwaghịm n'ọkụ, na-anyụ, na-akpụ ihe na-egbu egbu. Ọ dị mkpa iji chekwaa ngwaahịa ahụ n'ọchịchịrị, ebe akọrọ, ihe a rụchara arụchaala ihe ndị dị na ya na nchekwa nchekwa mgbe awa 6 gachara.

Dodoụbiga ya ókè

Mgbe ejiri ihe dị mma nke Oktolipen 600 mee ihe, a na-ahụkarị mgbaàmà nke isi ọwụwa: isi ọwụwa siri ike, mfu ikuala gị, yana ịbawanye mmetụta ndị dị ka ọgbụgbọ, ọgbụgbọ na ọgbụgbọ. Edere usoro ọgwụgwọ, nke a na-ewepu iwepu mmeghachi omume na-adịghị mma nke anụ ahụ. Nwere ike iwere: analgin, unyi na-arụ ọrụ, lavage gastric na-anabata, ma ọ bụ nkwụsị nke magnesium oxide na-anabata.

Nhazi ọkwa nosological (ICD-10)

Nkọwa nke ụdị usoro onunu ogwu

Ọgwụ ihe nkiri gbara agba site na ọkụ edo edo rue odo, odo, biconvex, nwere ihe ọghọm n’otu akụkụ. Na kink - si na odo na odo.

Capsules: siri ike opaque gelatin capsules Nke 0 edo edo. Ihe dị na capsules bụ ntụ ntụ nke edo edo edo ma ọ bụ agba odo. A na-anabata akwa nke agba ọcha.

Mlọ ọgwụ

Mgbe a na -ekwu ya ọnụ, ọ na-etinye obi gị dum na ngwa ngwa nri, ma iri nri na nri nwere ike belata mmịpụta nke ọgwụ.

Theụ ọgwụ ahụ, dịka ndụmọdụ ndị a na-atụ aro si dị, minit 30 tupu nri eri zere iso ndị mmadụ na-enwe mmekọrịta na-adịghị mma absorption nke thioctic acid n'oge nri ịba ụba emechaala. C_max A na - enweta thioctic acid na plasma ọbara 30 nkeji mgbe ị theụsịrị ọgwụ ahụ ma ọ bụ 4 μg / ml. Thioctic acid nwere mmetụta nke ibufe ọrịa imeju. Ezigbo bioavailability nke thioctic acid bụ 20%.

Metabolzọ metabolic bụ ụzọ dị mkpa bụ oxidation na conjugation. Ọ bụ akụrụ na -akpo Thioctic acid na metabolites ya (80-90%). Ndi_1/2 - Nkeji 25

Ime na lactation

Ihe ogwu ahu n'oge ime anakwo na ezighi ezi ulo ogwu na thioctic acid n’oge di ime.

Ọmụmụ nsị maka ọmụmụ adịghị ekpughe ihe egwu ọmụmụ, mmetụta na mmepe nwa ebu n'afọ, na akụrụngwa ọgwụ ọ bụla.

Ogwu Oktolipen ® n'oge a na-ara nwa ara na contraindicated na enweghị data na nbanye nke thioctic acid n'ime mmiri ara.

Ntụziaka pụrụ iche

Ndị ọrịa na-ewere Oktolipen ® kwesịrị ị®ụ mmanya, dị ka mmanya mmanya bụ ihe dị ize ndụ maka mmepe nke polyneuropathy ma nwee ike belata arụmọrụ ọgwụgwọ.

Ekwesịrị ịgwọ polyneuropathy na-arịa ọrịa shuga ka a na-eme ya mgbe ị na-ejigharị glucose dị n'ọbara.

Mmetụta ikike ịkwọ ụgbọala na usoro. Edebeghị mmetụta nke ike ịnya ụgbọ ala na usoro dị iche iche. Ekwesịrị ịkpachara anya mgbe ị na-anya ụgbọ ala ma na-eme ihe nwere ike ịdị ize ndụ na-achọ ịbawanye nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Mpempe mwepụta

Mbadamba ihe eji etinye fim, 600 mg. 10 mbadamba na ngwugwu na-acha uhie uhie nke eji eme ihe nkiri PVC ma ọ bụ PVC / PVDC na-ebubata, ma ọ bụ PVC / PE / PVDC na fodulum nke varnised dị mma.

3, 6, 10 blisters na-etinye na mkpọ nke kaadiboodu.

Capsules, 300 mg. Na ngwungwu ngwugwu, pcs 10. 3 ma ọ bụ 6 ngwungwu ngwugwu na kaadiboodu.

Emeputa

Site na mmepụta na JSC Pharmstandard-Tomskkhimfarm

Pharmstandard-Tomskkhimfarm OJSC 634009, 211 Lenin Ave., Tomsk, Russia.

Tel./fax: (3822) 40-28-56.

Site na imeputa na JSC Pharmstandard-Leksredstva

Pharmstandard-Leksredstva OJSC, 305022, Russia, Kursk, ul. Ọgbakọ nke abụọ, 1a / 18.

Tel./fax: (4712) 34-03-13.

Capsules OJSC Pharmstandard-Leksredstva, 305022, Russia, Kursk, ul. Ọgbakọ nke abụọ, 1a / 18.

Tel./fax: (4712) 34-03-13.

Analogues nke ọgwụ

Ọgwụ kachasị mma sitere na otu a bụ Oktolipen 600. Ntụziaka maka ojiji, ọnụahịa - ihe ndị a niile na-egosi na ngwá ọrụ a dị mma ma dị oke nhata maka ọtụtụ ọgwụ, dị ka Berlition na Neuroleepone - ndị nnọchianya nke otu ụdị ọgwụ ọjọọ.

Ndị ahịa na-eme nyocha

“Oktolipen 600” nwere ọtụtụ nyocha dị mma, dịka iwu, ọtụtụ ndị ọrịa ji ọgwụ a kpọrọ ihe nke ukwuu - ọ dị ọnụ ala karịa “Berlition”, mana ka arụ ọrụ karịa “NeroLipon”, n'ihi nsonaazụ ya kachasị mma maka ịzụta na ọgwụ.

A na-eresị ọgwụ ampouled na nkezi ọnụ ahịa nke 380 rubles, mbadamba nkume na capsules nke ọgwụ dọkịta nyere nwere ọnụ ahịa 290-300 rubles.

Ma cheta - lekọta ahụ ike gị. Ejila onwe gi ogwu, oktolipen mbadamba 600 kwesiri iwere ya aka mgbe ichochara dọkịta. Njikwa onwe gị nke ọgwụ na-enweghị ndenye ọgwụ dọkịta nwere ike ibute nsonaazụ ọjọọ maka ahụike gị, ọbụladị ọnwụ.

Ntụziaka maka iji ọgwụ Okolipen

Iji luso mgbaàmà nke ọrịa shuga ọgụ, dọkịta nwere ike inye ọgwụ Okolipen ọgwụ.

Ndị ọrịa kwesịrị ịma etu ọgwụgwọ a si dị ịtụnanya na otu o si emetụta ahụ.

Na mgbakwunye, ịkwesịrị ịchọpụta atụmatụ nke ọgwụ nwere ike ibute nsogbu. Nke a ga - enyere aka izere omume na - ezighi ezi ma nwekwuo arụmọrụ nke ọgwụgwọ.

Ozi izugbe

Oktolipen sitere na thioctic acid. Mgbe ụfọdụ enwere ike ịkpọ ọgwụ a lipoic acid, maka na o nwere otu ihe mejupụtara ya. Ebumnuche a chọrọ ikpochapụ ọtụtụ ọrịa.

O nwere otutu ihe bara uru:

• hepatoprotective
• hypoglycemic,
• neuroprotective
• hypocholesterolemic.

Can nwere ike ịchọpụta ihe mere eji etinye Oktolipen, site na ntuziaka. O kwesịrị ekwesị maka ọgwụgwọ nke ọrịa shuga, mana enwere ọrịa ndị ọzọ maka iwepụ nke ọ chọrọ.

Dọkịta kwesịrị inye gị ọgwụ ahụ. Ọ nwere ike ịtụle etu o si dị mma iji ya mee ihe n'otu ọnọdụ, họrọ usoro ọgwụgwọ ziri ezi ma nyochaa ọganihu nke ọgwụgwọ.

A na-emepụta Oktolipen na Russia. Purchasezụta ngwaahịa a n'ụlọ ahịa ọgwụ ị ga-eweta ọgwụ.

Ngwakọta, ụdị ntọhapụ

Ọgwụ dị n'ọtụtụ n'ụdị (capsules, mbadamba, ntụtụ). Nhọrọ nke ụdị ọgwụ dịgasị iche iche dabere na njiri nke ahụ onye ọrịa yana ụdị ọrịa ahụ. Isi ọrụ nke Octolipen bụ thioctic acid, nke bụ isi akụrụngwa.

Na mbadamba na capsules kwukwara ihe ndị dị ka:

• calcium hydrogen phosphate akpọnwụwo,
• gelatin ọgwụ
• stereị magnesium,
• titanium dioxide
• silica
• nwuo.

Mbadamba ụrọ na capsules dị iche iche na agba. Ọgwụ nke ihe nọ n'ọrụ n’ime ha bụ 300 na 600 mg. A na-ere ha na ngwugwu nke nkeji 30 na 60.

Ngwakọta infusion dị na mmiri mmiri, enweghị agba agba ma na-enweghị atụ.

Ngwa ihe ndị mejupụtara ya bụ:

Maka ịdị mma, etinye Oktolipen dị iche iche na ampoules.

Pharmacology na pharmacokinetics

Akụkụ nọ n'ọrụ nwere mmetụta dị ukwuu n'ahụ ahụ. Mgbe a na-ewere ya na ndị ọrịa, mgbanye ọbara shuga na-ebelata, ebe thioctic acid na-eme ka ọgụgụ insulin dịkwuo elu. N'ihi ya, sel na-anabata glucose ma ọ bụrụ na-ekesa ya.

Acid na - ewepu nsonaazụ nke ihe pathogenic, na - asacha ahụ nke ihe na - egbu egbu ma na - enyere aka ịkwalite ọgụ. N'ihi ya, a na-ebelata ego cholesterol, nke na-egbochi mmepe nke atherosclerosis. Na mgbakwunye, acid na-eme ka ọrụ imeju dịkwuo mma, na-emetụta usoro nke lipid na carbohydrate metabolism.

Mgbe a na -ekwu ya n'ọnụ, a na-etinye ọgwụ ahụ ma ekesa ngwa ngwa. Ọta ya ruru ogo ihe dị ka nkeji iri anọ. Enwere ike rụpụta arụmọrụ kachasị ukwuu site na ntụtụ. Oge iri nri na - emetụta oge ị ga - eri nri - ọ dị mma ị theụ ọgwụ tupu i rie nri.

Acid na-edozi ya. Otutu ihe a n’ewepu aru n’ariri n’onu. Ọkara ọkara na-ewe ihe dị ka otu awa.

Vidio banyere akụrụngwa nke thioctic acid:

Ihe ngosi na contraindications

Iji ọgwụ ọjọọ eme ihe ma ọ bụ iji ya eme ihe ọ bụla nwere ike imerụ onye ọrịa ahụ.

Ihe ngosi maka iji ogwu a:

• polyneuropathy na-ebute ọrịa shuga ma ọ bụ ahoụrụma (a na-eji ọgwụ mbadamba eme ihe),
• nsi nri site na nri ma obu ihe ojoo
• cirrhosis nke imeju
• hyperlipidemia,
• ụdị ịba ọcha n'anya A (n'ọnọdụ ndị a, a na-enye ihe eji eme ihe maka ntụtụ).

Ọzọkwa, enwere ike ịkwado ọgwụ ahụ maka ọrịa ndị anaghị apụta na ndepụta nke ihe ngosi. Anabatara nke a na usoro ọgwụgwọ siri ike.

Ọnụnọ nke nchoputa kwesiri ekwesi bu ihe di nkpa, ma enweghi anakpo contraindications bu ihe di nkpa. Ọ bụrụ na achọtara ha, a machibidoro iji Oktolipen iwu.

Ihe mgbochi:

• anabataghị ihe mejupụtara ya
• nke nwere umu
• nri eke
• afọ ụmụaka.

N'ọnọdụ ndị dị otú ahụ, ọgwụ ọgwụ Octolipen na-achọ onye ga-anọchi ya n'etiti ndị analogues.

Ndị Ọrịa na Nduzi Pụrụ Iche

Mgbe ị na-edenye ọgwụ ụfọdụ maka ụfọdụ ndị mmadụ, ịkpachara anya dị mkpa, ebe ọ bụ na ahụ ha nwere ike ịza ọgwụ a na-enweghị atụ.

Themfọdụ n’ime ha bụ:

1. Womenmụ nwanyị dị ime. Dabere na ọmụmụ, thioctic acid anaghị emerụ nwa ebu n'afọ na nne na-atụ anya, mana amabeghị nkọwa nke nsonaazụ ya n'ụzọ zuru ezu. N'ihi ya, ndị dọkịta na-ezere idebe Oktolipen n'oge a.
2. Womenmụ nwanyị na-azụ nri. Onweghi ihe omuma banyere ma mmanu ogwu nke aru oru di n’ime mmiri ara. N'akụkụ a, n'oge a na-enye nwa ara, anaghị eji ngwa a eme ihe.
3. Childrenmụaka na ndị nọ n'afọ iri na ụma. Ọ bụ enweghị ike igosipụta ịdị adị yana nchekwa nke thioctic acid maka ụdị ndị ọrịa a, ọ bụ ya mere a na-ewere ọgwụ ahụ dịka contraindicated maka ha.

Ndị ọrịa ndị ọzọ nwere ike iji ọgwụ ahụ ma ọ bụrụ na ha anaghị enwe ndidi.

Mgbe ị na-eji Oktolipen n'ime ndị nwere ọrịa shuga, mmadụ kwesịrị icheta ike nke thioctic acid iji belata ịba ọcha glu.

Nke a nwere ike ịkwalite nsonaazụ nke ndị ọrụ hypoglycemic ọzọ ma ọ bụrụ na onye ọrịa ahụ ewere ha. Yabụ, ị kwesịrị ị na-elele ọkwa shuga dị n'ọbara wee gbanwee usoro ị theụ ọgwụ ọjọọ dị na ya.

Akụkụ ọzọ dị mkpa nke ọgwụ ahụ bụ nsaghari nke ihe ọ kpatara n'okpuru mmanya. N'akụkụ a, ndị ọkachamara machibidoro ị ofụ mmanya n'oge usoro ọgwụgwọ.

Enweghi ihe omuma banyere otu Oktolipen si eme ihe na mmeghachi omume na itinye uche. Iji zere ihe ọghọm ndị enwere ike ime, a ga-akpachara anya mgbe ị na-anya ụgbọala yana ihe egwu dị egwu.

Njikọ Ọgwụ na Analogs

Ka ọgwụ ahụ wee na-arụpụta ihe, a ga-atụle atụmatụ ndị a

• Oktolipen na-eme ka mmetụta nke ndị na-arịa ọrịa hypoglycemic ọnụ na insulin,
• mgbe ejikọtara ọnụ, ọgwụ nwere ike belata arụmọrụ nke Cisplatin,
• Ekwesịrị ị nweta nkwadebe nwere iron, magnesium ma ọ bụ calcium tupu Oktolipen ma ọ bụ oghere dị ọtụtụ awa,
• ọgwụ kwalitere ọgwụ mgbochi mkpali nke glucocorticosteroids,
• n'okpuru mmetụta nke mmanya, arụmọrụ nke Octolipen n'onwe ya na-ebelata.

N'akụkụ a, ọ dị mkpa ịgbanwe dose nke ọgwụ ahụ ma nọgide na-agbatị oge. Ọ bụ ezie na ọ ka mma izere ijikọta ọgwụ a na ụzọ na-ekwesịghị ekwesị.

Mgbe ụfọdụ ndị ọrịa jụrụ ị thisụ ọgwụ a ma gwa ha ka ha họrọ ọgwụ analogues dị ọnụ ala. N'ọnọdụ ndị ọzọ, achọrọ onye nnọchi n'ihi nsogbu ọgwụ a dị iche iche.

Ogwu ejikọtara ọnụ gụnyere:

Ndị na-ahụ maka ahụike kwesịrị ịme nhọrọ ndị edochi Oktolipen.

Mkpebi nke ndị ọkachamara na ndị ọrịa

Site na nyocha nke ndị dọkịta banyere ọgwụ Okolipen, anyị nwere ike ikwubi na o yikarịrị ka etinyere ya na usoro ọgwụgwọ dị mgbagwoju anya maka oke ibu. N'ihe banyere ọrịa shuga, o yikarịrị ka nsogbu nke ụdị hypoglycemia dị elu.

Nyocha ndị ọrịa na - emegiderịta onwe ha - ọgwụ a na - enyere aka n'ibelata oke, mana na-egosipụta mmetụta ndị ọzọ na - eso ya.

Edere m Oktolipen nye ndị ọrịa m ugboro ugboro. Adabara ụfọdụ, ụfọdụ adịghị. Ngwá ọrụ na-enyere aka na nsi, na-ebelata ọkwa shuga, a na-arịọkarị ụmụ nwanyị ka ha depụta ya maka oke ibu. Mana, dị ka ọgwụ ọ bụla, ịkwesịrị ịkpachara anya na ya n'ihi contraindications na nsonaazụ ya.

Ekaterina Igorevna, dọkịta

Ana m akwado Oktolipen na analorọ ya na ndị ọrịa nwere oke ibu - na nke a ọ na - enyere aka n'ezie. Anaghị m akwado ya iji ya maka ndị ọrịa mamịrị. Ọ bụrụ na ha na-eji ọgwụ hypoglycemic eme ihe, mgbe ahụ Oktolipen nwere ike ibute ọrịa.

Irina Sergeevna, dọkịta

Ọgwụ a amasịghị m. N'ihi ya, shuga m dapụrụ nke ukwuu - dọkịta ahụ attentionaghị ntị n'eziokwu ahụ bụ na m nwere ọrịa mamịrị. N'ihi ọrịa hypoglycemia, adara m n'ụlọ ọgwụ. Acquainfọdụ ndị maara ama na-eto ọgwụ a, mana achọghị m itinye ya n'ihe egwu.

Ejiri Okolipen mee ihe maka oke ibu. N'izu mbu ahụ, ahụ ekweghị m; ọgbụgbọ na-emekpa m ahụ mgbe niile. M wee mara ya. Nsonaazụ ahụ masịrị m - na ọnwa 2, ewepụrụ m 7 n'arọ.

Iji zụta ọgwụ a na capsules, ịchọrọ site na 300 ruo 400 rubles. Mbadamba ụrọ (600 mg) na-eri 620-750 rubles. Ọnụahịa maka ịkwakọ Oktolipen nwere ampoules iri bụ 400-500 rubles.

Ihe ngosi maka iji Oktolipen

Ọgwụ Okolipen, ntuziaka maka ojiji akwadoro maka ọgwụgwọ nke polyneuropathy nke ọrịa mamịrị na onye aholicụrụma.

A na-ejikwa ya maka ọrịa ndị a:

• Ọrịa ịba ọcha n'anya
• Cirrhosis
• Neuralgia nke uzo nile di,
• Iji nnu mee ka ahụ banye n'ime ahụ.

Ọtụtụ nyocha banyere Oktolipen gosipụtara na ọ bụghị naanị maka polyneuropathies, kamakwa maka ọnọdụ dị iche iche mgbe usoro ụjọ ahụ chọrọ nkwado.

Ntụziaka maka iji Oktolipen, usoro onunu ogwu

Usoro onunu ogwu di iche iche: 50-400 mg / ubochi. Mgbe ụfọdụ, dọkịta depụtara ihe ruru 1000 mg, mana nke a bụ, enweghị atụ.

Ntụziaka gọọmentị maka Oktolipen anaghị atụ aro ịkarị 600 mg.

O kwere omume mepụta usoro ọgwụgwọ: nchịkwa ọnụ nke ọgwụ na-amalite mgbe izu ụka 2-4 nke parenteral (infusion) nchịkwa nke thioctic acid. Iri mbadamba kachasị oge bụ ọnwa 3.

Iji kwadebe osisa, a na-agbanye 300-600 mg nke ọgwụ ahụ na sodium chloride, a na-enye ọgwụ ahụ n'ọbara. A na-eme usoro ọgwụgwọ otu ugboro n'ụbọchị maka izu abụọ, izu anọ. Mgbe nke ahụ gasịrị, a na-egosi usoro ọgwụgwọ nke ọnụ (n'ọnụ).

A na - eji Oktolipen n'ụdị capsules ọnụ na 600 mg (okpu abụọ.) 1 oge / ụbọchị. A na-ewere okpokoro isi n'ụtụtụ, na afọ na-enweghị isi, nkeji iri atọ tupu nri mbụ, na-enweghị ata, na-a plentyụ nnukwu mmiri. Ọ bụ naanị dọkịta ka ọ ga-ekpebi oge ọ ga-amụ.

Njirimara ngwa

Ndị ọrịa chọpụtara ọrịa shuga mellitus kwesịrị ileba anya n'ihe dị iche iche dị n'ọbara glucose ọbara, ọkachasị n'oge mmalite nke ọgwụgwọ ya na Okolipen.

Enweghị data na nsonaazụ nke acid thioctic (α-lipoic) n'ikike ịnyacha usoro na ụgbọ ala.

Ọ bụrụ na a na-eme nhazi / infusion intravenous ngwa ngwa, enwere ihe ize ndụ nke nrụgide intracranial dịkwuo elu, ọdịdị nke nsogbu na sistem iku ume, yana ihe ndapụta. N'ihi mmetụta nke Oktolipen na platelet, ọbara ọgbụgba, oke ọbara n'ọbara na akpụkpọ ahụ ga-ekwe omume.

Oge nri n’otu oge na-ebelata oke ịgwọ ọrịa ọgwụ.

Ọgwụ a na-ahụ maka ọgwụ dị nro maka ọkụ, yabụ, ekwesịrị ịbara ampoules ozugbo tupu ojiji, ya bụ, tupu infusion.

Ndị ọrịa na-ewere Oktolipen kwesịrị ị fromụ mmanya ọ bụla nwere mmanya, dịka ethanol na metabolites ya na-ebelata oke ọgwụgwọ nke thioctic acid.

Mgbe ị na-a Okụ ọgwụ Okolipen, a naghị atụ aro iji mmiri ara ehi eme ihe (n'ihi ọdịnaya nke calcium n'ime ha). Oge dị n'etiti doses kwesịrị dịkarịa ala 2 awa.

Ọchịchị ahụ a na-ejikọta ya na Oktolipen ọgwụ na nkwadebe nke ígwè, magnesium na calcium anaghị akwadoro (n'ihi ntanetị nke usoro ya na ọla, etiti oge n’etiti doses kwesịrị dịkarịa ala elekere 2).

Analogs Okolipen, ndepụta

• Tiolepta
• Tiogamma
• Espa lipon
• Alfa lipoic acid,
• Ugbo ala,
• Lipamide
• Lipothioxone
• Neuroleipone.

Ihe dị mkpa - ntuziaka maka iji Oktolipen, ọnụahịa na nyocha nke analogues enweghị njikọ ma enweghị ike iji ya dịka nduzi ma ọ bụ ntụziaka. Nmeghachi ọgwụ ọ bụla na analog nke Octolipen kwesịrị ịdị n'okpuru nlekọta nke dibịa na-aga. N'agbanyeghi eziokwu na ọgwụ a na ọgwụ analogues ndị nwanyị na-ejikarị iji belata ibu, dọkịta nwere ahụmahụ kwesịrị ịdọ gị aka ná ntị maka nyocha ndị dị otú ahụ, ọ gwụla ma ọ bụrụ na ọ bụ mmebi nke carbohydrate na protein metabolism, yana mmezi ibu na ndị ọrịa mamịrị.