Insulin protafan NM: sirinji mkpirisi na nyocha

Iji belata ọkwa glucose ọbara dị elu, a na-eji ọgwụ eme ihe, ndị kachasị rụọ ọrụ bụ insulin. N'ime ụdị ọrịa shuga 1, mgbe ọrịa na-enweghị ike inye mkpa nke homonụ a, insulin bụ naanị ụzọ iji chekwaa ahụike na ndụ ndị ọrịa.

A na - enye insulin ike nwayọ dịka dọkịta si nye ya ma na - achịkwa shuga ọbara. Ngụkọta nke dose dabere na ọdịnaya nke carbohydrates na nri. A na-ekpebi usoro ọgwụgwọ iche iche maka onye ọrịa ọ bụla ma dabere na profaịlụ glycemic.

Iji mepụta insulin dị nso n'okike, a na - eji insulins eme ihe ogologo. Nnukwu ihe ndị dị n'etiti gụnyere ndị ọrụ ụlọ ọrụ Danish Novo Nordisk rụpụtara - Protafan NM.

Mwepụta weputara ya na ebe nchekwa Protafan

Nkwụsị ahụ nwere insulin - isophan, ya bụ, insulin mmadụ mepụtara site na inyocha mkpụrụ ndụ ihe nketa.

N'ime 1 ml ọ nwere 3.5 mg. Na mgbakwunye, enwere excipients: zinc, glycerin, sulfate protamine, phenol na mmiri maka ịgba ntụtụ.

Ewepụtara insulin Protafan hm n'ụdị abụọ:

Nkwụsị nke nchịkwa subcutaneous 100 100 IU / ml 10 ml na vials jiri mkpuchi roba kpuchie ya, nke a na-ejikwa aluminom na-agba. Karama ahụ ga-enwerịrị mkpuchi nchebe. Na ngwugwu, na mgbakwunye na karama ahụ, enwere ntụziaka maka ojiji.
Protafan NM Penfill - na katriki dị na hydrolytic, kpuchie ya na diski roba dị n'otu akụkụ na pistons roba n'akụkụ nke ọzọ. Iji mee ka agwakọta, a na-etinye bọọlụ iko iko ahụ.
A na-akanye mkpụrụakụ nke ọ bụla n'ime mkpịsị akwụkwọ Flexpen. Ihe ngwugwu a nwere pensụl na ntụziaka 5.

N'ime karama 10 nke protafan insulin nwere 1000 IU, yana mkpịsị mkpụrụ siliọnu 3 ml - 300 IU. Mgbe ọ na-eguzo ọtọ, a na-emechi nkwusioru ahụ ka ọ bụrụ mmiri na mmiri na-enweghị ụcha, yabụ agụnyere agwakọta ihe ndị a tupu ijiri ya.

Iji chekwaa ọgwụ a, a ga-etinye ya n'etiti shelf nke friji, okpomọkụ nke ekwesiri idobe ya site na ogo 2 ruo 8. Zere iwere ọkụ. Ọ bụrụ na emepee kalama Protafan NM Penfill mepee emepe, mgbe ahụ ka edobere ya na temprechọ ime ụlọ, mana ọnaghị elu karịa 25 Celsius. Ojiji insulin Protafan ga-emerịrị n'ime izu isii.

A naghị echekwa Flexpen na friji, okpomọkụ iji nọgide na-enwe ụlọ ọgwụ ya ekwesịghị ịdị elu karịa ogo 30. Iji chebe site na ọkụ, a ga-etinyerịrị okpu n'isi. A ga-echedorịrị ihe ahụ n'aka mmebi yana ihe ndị mebiri emebi.

A na-ehicha ya site na mpụta ya na akwa owu na-egbu egbu na-egbu egbu, a gaghị emikpu ya na mmiri ma ọ bụ tee ya mmiri, n'ihi na nke a na-emebi usoro ahụ. Ejikwala mkpịsị ede edewuriro.

A na-enyefe akwụkwọ nkwado na ụdị penfill na katriji ma ọ bụ mkpịsị akwụkwọ site n'ụlọ ahịa ọgwụ site na ndenye ọgwụ.

Pricegwọ maka insulin n'ụdị pen (Flexpen) dị elu karịa nke Protafan NM Penfill. Ọnụahịa kachasị ntakịrị maka nkwụsị na karama.

Etu esi eji Protafan?

A na - eji insulin Protafan NM eme ihe naanị. Agaghị atụ aro maka nchịkwa nke intrauscular. Ejighi ya mejupụta insulin. Gbalịsie ike lelee okpu nchebe mgbe ị na-azụ ụlọ ahịa ọgwụ. Ọ bụrụ na ọ nọghị ma ọ bụ tọghee, ejila insulin.

A na-ewere ọgwụ a dị ka nke na-adịghị mma ma ọ bụrụ na emebi emebi ọnọdụ nchekwa ma ọ bụ kpoo ya, ma ọ bụrụ na mgbe agwakọchara ya, ọ gaghi abụ otu - ọcha ma ọ bụ igwe ojii.

A na - ejikwa insulin ma ọ bụ mkpịsị insulin na - eme insulin. Mgbe ị na-eji sirinji, ịkwesịrị ịmụ banyere ogo ọrụ ihe. Mgbe ahụ, a na-adọta ikuku n'ime sirinji tupu nkewa nke insulin na-atụ aro. A na-atụ aro ka iji aka gị kwatu vial ahụ. A na-ewebata Protafan naanị mgbe nkwusiri ahụ ghọrọ usoro ime mmụọ.

Flexpen bụ mkpịsị sirinji juputara na ikike ịza site na nkeji 1 ruo 60. Ejiri ya mee ihe na NovoFayn ma ọ bụ NovoTvist agịga. Ogologo agịga bụ 8 mm.

A na-eji mkpịsị ọrịre eme ihe dị ka iwu ndị a:

Lelee akara na iguzosi ike n'ihe nke pen ọhụrụ.
Tupu ojiji insulin kwesịrị ịdị n ’ụlọ okpomọkụ.
Wepu okpu ma bugharia aka ya ugboro iri abụọ ka bọọlụ iko ahụ wee nwee ike ịga ije na katriiki.
Ọ dị mkpa ịgwakọta ọgwụ ahụ ka o wee nwee urukpuru.
Tupu inje ọzọ, ịkwesịrị ịkwaga aka ahụ elu ma dịkarịa ala ugboro iri.

Mgbe ịkwesịrị nkwusio ahụ, a na-eme ntụtụ ahụ ozugbo. Maka nguzobe ihe mgbochi edo na mkpịsị akwụkwọ kwesịrị ịbụ ihe na-erughị 12 IU nke insulin. Ọ bụrụ na ọnweghị ego achọrọ, ọ ga-eji nke ọhụrụ.

Iji kegide agịga ahụ, a na-ewepụ ihe mmado na-echebe ya wee na-agagharị agịga na pen sirinji. Mgbe ahụ ịkwesịrị iwepu okpu dị na mpụta, yana nke ime.

Iji gbochie ụfụfụ ikuku ịbanye na saịtị ịgba ahụ, pịa nkeji 2 site na ịpị onye na-ahọrọ ya. Mgbe ahụ tụọ agịga elu ma pịa katriji ka ịhapụ ụfụfụ. Pịa bọtịnụ mmalite oge niile, mgbe onye ahọpụtara na-alaghachi efu.

Ọ bụrụ na dobe insulin apụta na njedebe nke agịga, ị nwere ike ịgbanye. Ọ bụrụ na enweghị dobe, gbanwee agịga. Mgbe ị gbanwere agịga ugboro isii, ịkwesịrị ịkagbu ojiji ahụ, n'ihi na ọ nwere nkwarụ.

Iji gosipụta insulin, ọ dị mkpa ịgbaso omume ndị a:

Dose selector ga-efu.

Tụgharịa onye na-ahọrọ ihe n'akụkụ ọ bụla iji họrọ otu dose site na ijikọ ya na pointer. N'okwu a, ịnweghị ike pịa bọtịnụ mmalite.
Were anụ ahụ na mmanye ma tinye agịga ahụ n'ime ntọala ya na ogo 45.
Pịa bọtịnụ “mbido” ruo mgbe “0” pụtara.
Mgbe itinyechara ya, agịga kwesịrị ịdị n'okpuru anụ ahụ maka sekọnd isii iji nweta insulin niile. Mgbe ị na-ewepụ agịga ahụ, a ghaghị ijide bọtịnụ mmalite.
Tinye okpu na agịga na mgbe nke ahụ gasịrị, enwere ike iwepu ya.

A naghị akwado ya iji agịde dochie Flexpen, ebe insulin nwere ike ipu. A ga-eji nwayọ kpochapụ agịga ndị ahụ, na-ezere inje na mberede. Isi sirinji na mkpịsị akwụkwọ niile bụ maka onwe ya.

A na-ewebata insulin ji nwayọ nwayọ banye na akpụkpọ apata ụkwụ, ụzọ njikwa ngwa ngwa nke nchịkwa abanyekwa n'ime afọ. Maka ntụtụ, ị nwere ike ịhọrọ gluteus ma ọ bụ deltoid muscle nke ubu.

Ekwesịrị ịgbanwe saịtị ntụtụ ka ọ ghara ibibi abụba dị n'okpuru ala.

Nzube na usoro onunu ogwu

Insulin na-amalite ime ihe dị ka elekere 1,5 site na nchịkwa, ruru oke n'ime awa 4-12, ka ewepụtara na otu ụbọchị. Ihe kachasị egosi maka iji ọgwụ ahụ bụ ọrịa shuga.

Usoro nke usoro hypoglycemic nke Protafan nwere njikọ na nchịkwa nke glucose n'ime sel na mkpali nke glycolysis maka ike. Insulin na-ebelata mmebi nke glycogen na inwe glucose n’imeju. Site n'okpuru nduzi nke Protafan, a na-echekwa glycogen na mpaghara n'ime akwara na umeji.

Protafan NM na-eme ka njikọ protein na uto, nkewa nke sel, na-ebelata mmebi protein, n'ihi nke gosipụtara mmetụta anabolic ya. Insulin na-emetụta akwara adi adi, na -ebelata ogwe abụba ma na-abawanye nkwụnye ya.

A na-ejikarị ya na ọgwụgwọ ọgwụgwọ maka ụdị shuga 1 na-arịa insulin. Obere oge, a na-enye ya ndị ọrịa nke ụdị nke abụọ n’oge usoro ịwa ahụ, njikọta nke ọrịa na-efe efe, n’oge ime.

Ime ime, dị ka lactation, abụghị contraindication maka iji insulin a. Ọgaghị agafe Plasenta ma ọ nweghị ike ịmụrụ nwa nwere ara ara. Ma n’oge ime na ịrara ara, ị kwesịrị iji nwayọ họrọ ma dozigharị oge niile iji mee ka ogo glucose dị n’ọbara.

Enwere ike ịkọwa Protafan NM ma enwere onwe ya yana yana insulin ma ọ bụ nke dị mkpụmkpụ. Ọgwụ a dabere na ọkwa shuga yana mmetụta nke ọgwụ. Site na oke na oke uto, mgbe ọ nwere nnukwu ahụ elu. Na-emekwa ka mkpa insulin dị na ọrịa nke usoro endocrine.

Ọgwụ ezughi oke, nguzogide insulin ma ọ bụ ihie ụzọ na-ebute hyperglycemia site na mgbaàmà ndị a:

Obi mgbawa bilitere.
Ike na-arịwanye elu.
Gha ugboro ugboro.
Agụụ na-ebelata.
Isi nke acetone si n'ọnụ ya.

Ihe mgbaàmà ndị a nwere ike ịbawanye n'ime awa ole na ole, ọ bụrụ na shuga adịghị ala, mgbe ahụ ndị ọrịa nwere ike ịmalite ketoacidosis na-arịa ọrịa shuga, na-eduga na nsonaazụ dị egwu, karịsịa na ụdị shuga 1.

Nsonaazụ nke Protafan NM

Hypoglycemia, ma ọ bụ iwetu shuga dị n'ọbara, bụ ihe ndị dịkarịsịrị njọ ma dị ize ndụ nke ị effectụ ọgwụ inulin. Ọ na - ebilite na nnukwu onyonyo, mgbali anụ ahụ, nri echefuru.

Mgbe akwụghachi ọkwa shuga, ihe mgbaàmà hypoglycemia nwere ike gbanwee. Site n'ịgwọ ọrịa shuga ruo ogologo oge, ndị ọrịa na-efunahụ ikike ha ịghọta mmalite shuga. Ọgwụ ndị a na-eji belata ọbara mgbali elu, ọkachasị ndị na-abụghị ndị na - akpọ beta-mgbochi na ọgwụ mgbochi, nwere ike ịgbanwe ihe ịrịba ama mbụ.

Ya mere, a na-atụ aro ịka ọkwa shuga ugboro ugboro, ọkachasị na izu mbụ nke iji Protafan NM ma ọ bụ mgbe ị na-agbanye ya na insulin ọzọ.

Ihe ịrịba ama izizi nke iwetulata shuga dị n'okpuru ala nwere ike ịbụ:

Anya isi mberede, isi ọwụwa.
Mmetụta ụjọ, iwe.
Mmegide nke agụụ.
Ọcha.
Nnukwu aka.
Ọkpụkpụ nkụ na obi mgbawa.

N'ọnọdụ siri ike, yana ọrịa hypoglycemia n'ihi nsogbu nke ụbụrụ, ọgba aghara, ọgba aghara na-etolite, nke nwere ike ibute coma.

Iji wepu ndị ọrịa hypoglycemia n'ọnọdụ ndị dị nro, a na-atụ aro ị toụ shuga, mmanụ a orụ ma ọ bụ glucose, ihe ọ juiceụ sweetụ ụtọ. N'ihe banyere mmụọ ịta ahụhụ, 40% glucose na glucagon na-agbanye n'ime akwara. Mgbe ahụ ịchọrọ nri nwere carbohydrates dị mfe.

Site na nnagide insulin, mmeghachi omume nfụkasị ahụ n'ụdị ihe ọkụ ọkụ, dermatitis, urticaria nwere ike ịdapụta, n'ọnọdụ ndị adịkarịghị akpata ụjọ anaphylactic. Enwere ike gosipụta nsonaazụ n'akụkụ mmalite nke ọgwụgwọ site na mmebi nke ntụgharị uche na mmepe nke retinopathy, ọzịza, mmebi nke akwara ozi n'ụdị ụdị neuropathy na-egbu mgbu.

N’ime izu izizi nke ọgwụgwọ insulin, ọzịza, ọsụsọ, isi ọwụwa, ehighị ụra, ọgbụgbọ, na ịbawanye obara nwere ike ịba ụba. Mgbe ọ usedụchara ọgwụ ahụ, mgbaàmà ndị a na-ebelata.

Enwere ike ịza, itching, redness, ma ọ bụ ọnya na ebe insulin insulin.

Mpempe usoro onunu ogwu

Nkwụsị ahụ maka nchịkwa s / c nke agba ọcha, mgbe ọ mebiri emebi, na-etolite ntụpọ ọcha na nke enweghị agba ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ nke enweghị agba, na-akpali akpali, a ga-atụgharịghachi ikuku ahụ

isofan insulin (inyocha mkpụrụ ndụ mmadụ) 100 IU *

Ndị ọkachamara: zinc chloride, glycerol, metacresol, phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, hydrochloric acid na / ma ọ bụ sodium hydroxide ngwọta (iji nọgide na-enwe pH), mmiri d / na.

* 1 IU dabara na 35 μg nke insulin na-eme mmadụ.

Mlọ ọgwụ

Protafan® NM Penfill® bụ ihe na - anọchi anya insulin mmadụ na-ahụ maka biosynthetic, nke mejupụtara isofan-insulin.

A na - eme insulin mmadụ na - arụ ọrụ site na iji teknụzụ DNA jikọtara ọnụ na - eji sel yist dị ka ihe na - emepụta ihe. Ọgwụ bụ ọgwụ insulin na-akpata insulin na mmadụ.

N'ime uwe mwụda Penfill® nwere bọọlụ iko na-arụ ọrụ na-ekesa ihe insulin ọcha n'otu. Mgbe ị tụgharịrị Penfill ma gbadaa ọtụtụ oge, mmiri mmiri ahụ na-aghọ ihe dull ọcha na edo.

Profaịlụ nke ime ihe na injection subcutaneous (ihe ruru ọnụ ọgụgụ):

mmalite nke ime ihe mgbe awa 1.5 gachara, nsonaazụ kachasị: site na awa 4 ruo 12, oge ọrụ: 24 awa.

Atụmatụ ire

- insulin na-arịa ọrịa shuga mellitus (ụdị nke m),

- ọrịa mellitus na-arịa insulin na-abụghị insulin (ụdị II): ọkwa nke iguzogide ndị ọrịa hypoglycemic ọnụ, nguzogide ele mmadụ anya na ọgwụ ndị a (n'oge ọgwụgwọ njikọta), ọrịa intercurrent, arụmọrụ, ịtụrụ ime.

Mkparịta ụka ọgwụ ọjọọ

Enwere ọtụtụ ọgwụ na-emetụta chọrọ insulin. Ya mere, ọ bụrụ n’ị na-a medicationsụ ọgwụ ọ bụla, gwa dọkịta gị.

You nwere ike ịzụta Protafan nm penfill 100me / ml 3ml n5 katriki na Moscow na ụlọ ahịa ọgwụ ga-adabara gị mma site na itinye iwu na Apteka.RU.
Pricegwọ nke Protafan nm penfill 100me / ml 3ml n5 cartridges na Moscow bụ 800,00 rubles.
Ntụziaka maka iji Protafan nm penfill 100me / ml 3ml n5 katọn.

Nwere ike ịhụ isi nnyefe kacha nso na Moscow ebe a.

Ahịa maka Protafan Nm n’obodo ndị ọzọ

Ọ bụ dibia a ka edobere ọgwụ iji dozie ọgwụ ọ bụla. A na-eji ọgwụ ahụ eme ihe naanị maka ọgwụ ntụtụ. Mgbe ọ gbasịrị, agịga kwesịrị ịdị n’okpuru anụ ahụ ruo ọtụtụ sekọnd, nke na -eme ka ị fullụ ọgwụ zuru oke.

N'ihe banyere mellitus na-arịa ọrịa shuga (ụdị nke m), a na-eji ọgwụ ahụ eme insulin basal yana nkwadebe insulin na-eme ngwa ngwa.

Site na mellitus na-arịa insulin na-abụghị insulin (ụdị II), enwere ike iji ọgwụ ahụ mee ihe dị ka monotherapy yana yana insulins na-eme ngwa ngwa.

Mgbe ị na-ebufe onye ọrịa site na ezì dị ọcha ma ọ bụ insulin nke mmadụ na Protafan NM Penfill, ị doseụ ọgwụ ahụ ka na-agbanwe otu ihe.

Mgbe ị na-ebufe site na anụ ehi ma ọ bụ insulin gwakọtara ya na Protafan NM Penfill, ekwesịrị ịbelata dose ahụ site na 10%, ọ gwụla ma usoro mbu ahụ erughị 0.6 U / n'arọ ahụ.

N'ihe dị kwa ụbọchị gafere 0.6 U / n'arọ, a ghaghi inye insulin ụdị n'ụtụtụ abụọ ma ọ bụ karịa na ebe dị iche iche

Njikọ Ọgwụ

Oge nchịkwa ọgwụ nwere ike ịkwalite mmetụta nke insulin. Ndị a gụnyere monoamine oxidase inhibitors (Pyrazidol, Moclobemide, Silegilin), ọgwụ antihypertensive: Enap, Kapoten, Lisinopril, Ramipril.

Ọzọkwa, ojiji nke bromocriptine, steroid anabolic, Colfibrate, Ketoconazole na Vitamin B6 na-abawanye ohere nke hypoglycemia na ọgwụgwọ insulin.

Ọgwụ Hormonal nwere mmetụta nke otu: glucocorticosteroids, homonụ thyroid, mgbochi nke a na-ede ede, antidepressanma tricyclic na thiazide.

Enwere ike ịbawanye elu na insulin insulin mgbe ị na-ede akwụkwọ Heparin, ndị na-egbochi calcium, Danazole na Clonidine, vidiyo dị n'isiokwu a ga-enye ozi banyere protofan instofan ọzọ.

Protafan insulin: nkọwa, nyocha, ọnụahịa

Insulin Protafan na-ezo aka na insulin na-arụ ọrụ mmadụ.

Mkpa iji ọgwụ insulin Protafan HM Penfill nwere ike ịpụta nwere ọtụtụ ọrịa na ọnọdụ. Nke mbu, jiri udiri oria 1 di ya. Na mgbakwunye, ọgwụ ahụ gosipụtara na ọkwa nke iguzogide ọgwụ hypoglycemic mbụ.

A na-ejikwa ọgwụ a na usoro ọgwụgwọ agbakwụnyere (ọgwụ mgbochi ntakịrị na ọgwụ hypoglycemic ọgwụ), ma ọ bụrụ na a na-achọpụta ọrịa shuga n'ime ụmụ nwanyị dị ime ọ bụrụ na ọgwụgwọ nri anaghị enyere aka.

Ọrịa ọgbụgba na mgbochi ịwa ahụ (jikọtara ma ọ bụ monotherapy) nwekwara ike ịbụ ihe kpatara agba a.

Njirimara nke ogwu

Ọgwụ bụ nkwusioru ewepụtara n’okpuru anụahụ.

Otu, ihe na-arụ ọrụ:

Isulin insulin-mmadu semisynthetis (semisynthetic mmadu). O nwere nkezi oge ihe.Protafan NM bụ contraindicated na: insulinoma, hypoglycemia na hypersensitivity na-arụ ọrụ.

Etu esi ewere na n’ime usoro onunu ogwu?

A na-etinye insulin otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị, ọkara otu awa tupu nri ụtụtụ. N'okwu a, ebe a ga-eme inje, ọ ga-agbanwe ya mgbe niile.

Ekwesịrị ịhọrọ dose ahụ maka onye ọrịa ọ bụla n'otu n'otu. Olu ya na-adabere n’otú glucose dị n’ime mmamịrị na ọbara ọbara, yana n’omume nke otu ọrịa. N'ụzọ bụ isi, a na-enye ọgwụ ahụ otu oge kwa ụbọchị ma ọ bụ 8-24 IU.

N'ime ụmụaka na ndị okenye nwere insulin, a na-ebelata ogo ahụ ka ọ bụrụ 8 IU kwa ụbọchị. Ma maka ndị ọrịa nwere oke mmetụ uche, dibịa na-aga ahụ nwere ike ịkọtara otu ọgwụ karịrị 24 IU kwa ụbọchị. Ọ bụrụ na ọgwụ kwa ụbọchị karịrị 0.6 IU kwa kilogram, mgbe ahụ ọgwụ ọgwụ abụọ na-ahụ maka ọgwụ abụọ, nke a na-eme n'ebe dị iche iche.

Ndị ọrịa na-anata 100 IU ma ọ bụ karịa kwa ụbọchị, mgbe ha na-agbanwe insulin, ha ga-anọrịrị na-elekọta ndị dọkịta mgbe niile. Should ga-eji dochie ọgwụ ọzọ site na ilele ọkwa glucose ọbara.

Ngwongwo ogwu

Njirimara nke insulin Protafan:

lowers ọkwa glucose ọbara,
na-eme ka akpịrị gwọọ glucose na anụ ahụ,
na-eme ka njikọ protein dị mma,
lowers ọnụọgụ nke ịmịkọ nke imeju,
na-ebuli glycogenogenesis,
na-eme ka lipogenesis dịkwuo mma.

Microinterakti na ndị na-anabata ya na mejupụtara sel ahụ dị n’èzí na-akwalite nguzobe ụlọ ọrụ nnabata insulin. Site na mkpali na sel imeju na abụba, njikọ nke ma ọ bụ nnabata n’ime akwara ma ọ bụ sel, nnabata nke insulin na-arụ ọrụ n’usoro nke dị n’ime sel.

Ọ na - amalite njikọ nke ụfọdụ enzymes isi (glycogen synthetase, hexokinase, pyruvate kinase, wdg).

Nbelata nke glucose ọbara bụ:

ụba glucose na-abanye n'ime mkpụrụ ndụ,
mkpalite nke glycogenogenesis na lipogenesis,
ịba ụba na nnabata glucose site na anụ ahụ,
njikọ protein
mbelata na ọnụego shuga nke imeju na-amịpụta, i.e. mbelata nke mmebi nke glycogen na ndi ozo.

Nsonaazụ

Hypoglycemia (ọhụhụ na anya na okwu, pallor nke anụ ahụ, mmegharị mgbagwoju anya, ịba ụba, njiri mara, palpitations, mgbakasị ahụ, ịma jijiji, ịda mba, ụba agụụ, ụjọ, mkparị, ehighị ụra, nchekasị, ụra ụra, paresthesia n'ọnụ, isi ọwụwa. ,

Mmeghachi omume nfụkasị ahụ (mbelata ọbara mgbali, urticaria, mkpụmkpụ ume, fever, angioedema),

Mmụba na otu ụzọ titter nke ọgwụ mgbochi insulin na mmụba nke glycemia,

Ọrịa mamịrị acidosis na hyperglycemia (megide nzụlite nke ọrịa na ahụ ọkụ, ụnwụ nri, nsị na-enweghị atụ, ntakịrị ntakịrị): nsị ihu, ụra, agụụ, agụụ, agụụ mgbe niile.

Na nmalite ọgwụgwọ mbụ - njehie na edema (ihe na-adị nwa oge nke na-ebute ọgwụgwọ ndị ọzọ),

Mwepu nke nsụhọ (mgbe ụfọdụ stema na precoatose steeti amalite),

N'ebe a na-agbanye ya, itching, hyperemia, lipodystrophy (hypertrophy ma ọ bụ atrophy nke abụba subcutaneous),

Na mbido ọgwụgwọ bụ nsogbu nke anya na-adịghị ala ala,

Mmeghachi omume mgbochi nke mmadụ na insulin.

ogwe
igba ajirija
hypoglycemic coma,
nkuchi obi
ehighi ura
ọhụụ na-adịghị mma,
ịma jijiji
ndaghari
iro ụra
mụbara agụụ
omume di iche
nchegbu
mgbakasị ahụ
paresthesia na onu ogugu,
ịda mba
pallor
tua egwu
isi ọwụwa.

Etu esi eleghara ịdoụbiga mmanya ókè?

Ọ bụrụ na onye ọrịa nọ n'ọnọdụ ahụ, mgbe ahụ dọkịta deputara dextrose, nke a na-enye site na dropper, intramuscularly ma ọ bụ intravenously. A na-ejikwa Glucagon ma ọ bụ usoro dextrose hypertonic deprorose.

A bụrụ na mmepe nke hypoglycemic coma, 20 ruo 40 ml, i.e. Mpempe 40% dextrose ruo mgbe onye ọrịa na-apụta site na Coma.

Tupu i were insulin site na ngwugwu ahụ, ịkwesịrị ịlele na ihe ngwọta dị n'ime karama ahụ nwere agba agba. Ọ bụrụ n'igwe ojii, mmiri ma ọ bụ akụkụ ala ọzọ ka ahụrụ, amachibidoro ya.
Okpomoku nke ogwu tupu ochichi kwesiri ibu ulo.
Na ọnụnọ nke ọrịa na-efe efe, ịrụ ọrụ nke glandị thyroid, ọrịa Addiosn, ọdịda akụrụ na-adịghị ala ala, hypopituitarization, yana ndị ọrịa shuga agadi, ọgwụ insulin kwesịrị ka edozi ya n'otu n'otu.

Ihe na - akpata hypoglycemia nwere ike ịbụ:

nnyefere
vomiting
ọgwụ ịgbanwe
ọrịa na-ebelata mkpa insulin (ọrịa imeju na akụrụ, hypofunction nke thyroid gland, pituitary gland, adrenal cortex),
Emeghị ihe oriri,
nmekorita ya na ogwu ndi ozo
afọ ọsịsa
anụ ahụ arụ,
mgbanwe nbanye saịtị.

Mgbe ị na-ebufe onye ọrịa si insulin anụmanụ n’ime insulin mmadụ, mbelata nke glucose ọbara nwere ike pụta. Ntughari na insulin nke mmadụ kwesiri ịbụ ihe ziri ezi site na elele ahụike, ekwesịrị ịme ya n'okpuru nlekọta dọkịta.

N'oge ịmụ nwa na mgbe a mụsịrị nwa, enwere ike belata mkpa nke insulin. N’oge ị na-agba ara, ịkwesịrị ilebara nne gị anya ọtụtụ ọnwa, ruo mgbe ọ ga-egbo mkpa insulin.

Ihe nwere ike ime ka ọrịa hypoglycemia na-arịa ọrịa nwere ike ime ka mmadụ nwekwuo ike ịnya ụgbọ ma nwee usoro na igwe.

Site n'enyemaka nke shuga ma ọ bụ nri nwere nnukwu ọdịnaya nke carbohydrates, ndị ọrịa mamịrị nwere ike ịkwụsị ụdị hypoglycemia dị nro. Ọ bụ ihe amamihe dị na ya na onye ọrịa a nwere shuga dịkarịa ala 20 mgbe niile.

Ọ bụrụ na eyigharị hypoglycemia, ọ dị mkpa ịgwa dọkịta onye ga-eme mgbanwe ọgwụgwọ ahụ.

N’ime afọ ime, a ga-elele mbelata (1 ọkara) ma ọ bụ ịrị elu (2-3 ọkara) nke ahụ ịchọrọ insulin.

Mmekọrịta na ọgwụ ndị ọzọ

MA inhibitors (selegiline, furazolidone, procarbazine),
sulfonamides (sulfonamides, ọgwụ nke hypoglycemic).
NSAIDs, ACE inhibitors na salicylates,
steroid anabolic na methandrostenolone, stanozolol, oxandrolone,
carbonic anhydrase inhibitors,
ethanol
androgens
chloroquine
bromocriptine
quinine
tetracyclines
quinidine
ekwo ekwo
pyridoxine
ketoconazole,
Li + njikere,
mebendazole,
theophylline
fenfluramine,
cyclophosphamide.

Ihe mgbochi H1 - vitamin na-anabata ya,
glucagon,
epinephrine
somatropin,
ihe ndapụta
GKS,
nikotin
ogwu gboro ya
wii wii
estrogens
morphine
loop na thiazide diuretics,
diazoxide
BMKK,
Ndị na-emegide nnu
homonụ thyroid,
clonidine
heparin
tricyclic antidepressants,
sulfinpyrazone
danazol
nnabata ọmiko.

E nwekwara ọgwụ ọgwụ ndị nwere ike ime ka ike gwụ insulin na mmụba nke insulin. Ndị a gụnyere:

pentamidine
ihe mgbochi beta,
octreotide
reserpine.

Protafan nm penfill - ntuziaka maka ojiji, ọnụahịa, nyocha na analogues

Protafan NM Penfill bụ onye na-ahụ maka ọgwụgwọ nke ebumnuche ya na ọgwụgwọ nke ọrịa shuga mellitus. Ogwu a, mgbe ejiri ya mee ihe n’ụzọ ziri ezi, na-enye gị ohere ịgbanye ọkwa glucose dị n’ọbara, n’emebighị ahụike onye ọrịa.

International Nonproprietary Aha

A.10.A.C - insulins na analorọ ha na nkeji nke ihe ha mere.

Nkwụsị nke nchịkwa subcutaneous 100 IU ml dị n'ụdị: karama (10 ml), katriiki (3 ml).

Ngwakọta nke 1 ml nke ọgwụ ahụ nwere:

Ihe eji eme ihe: insulin-isophan 100 IU (3.5 mg).
Ihe inyeaka: glycerol (16 mg), zinc chloride (33 μg), phenol (0.65 mg), sodium hydrogen phosphate dihydrate (2.4 mg), protamine sulfate (0.35 mg), sodium hydroxide (0.4 mg) ), metacresol (1.5 mg), mmiri maka injection (1 ml).

Nkwụsị nke nchịkwa subcutaneous 100 IU ml dị n'ụdị: karama (10 ml), katriiki (3 ml).

Omume ọgwụ

Na-ezo aka na ndị na-ahụ maka hypoglycemic nwere oge ọrụ ha. A na-emepụta teknụzụ DNA recombinant site na iji Saccharomyces cerevisiae. Ọ na - emekọ ihe na ndị na - anabata membrane, na - akpụpụta insulin-receptor complex nke na - eme ka njikọ nke enzymes tinye aka na ndụ (hexokinases, glycogen synthetases).

Ọgwụ na-akpali ntụgharị nke protein n’ahụ́ niime sel nke ahụ. N'ihi nke a, a na - eme ka glucose na - adịwanye mma, a na - akpali lipo- na glycogenesis, a na --ebelata nri glucose site na imeju. Ọzọkwa, arụ ọrụ protein na-arụ ọrụ.

Mlọ ọgwụ

A na-ekpebi ịdị irè nke ọgwụ na ọsọ nke nrube ya site na usoro onunu ogwu, ọnọdụ nchịkwa, usoro ntụtụ (subcutaneous, intramuscular), ọdịnaya insulin na ọgwụ. Ọbara dị n’ọbara dị n’iru na-erute mgbe awa 3-16 gachara irighiri ụrọ.

Etu esi ewere Protafan NM Penfill?

Mee ọgwụ irighiri akwara ma ọ bụ okirikiri. A na-ahọrọ usoro onunu ogwu na-eburu n'uche nkọwa na ọrịa ahụ. Onwere ike ịkwado insulin dịgasị n'etiti 0.3-1 IU / kg / ụbọchị.

A na-eji mkpịsị ọrịrị kwee insulin. Ndị nwere insulin na-eguzogide ọgwụ na-ahụkarị ihe insulin na-arị elu (n'oge mmepe mmekọahụ, oke ahụ dị oke), ya mere, a na-enye ha ọgwụ kachasị.

Iji belata ihe ize ndụ nke lipodystrophy, ọ dị mkpa ịme ọzọ ebe nlekọta ọgwụ. A machibidoro nkwusioru, dika ntuziaka a si di, machibidoro iwu ịbanye na intra.

Na-arịa ọrịa shuga

A na-eji Protafan mee ihe maka ụdị ọrịa shuga ọ bụla. Usoro ọgwụgwọ ahụ na-amalite site n'ọrịa shuga 1. Edere ụdị ọgwụ 2 ahụ ma ọ bụrụ na enweghị nsonaazụ sitere na usoro sulfonylurea, n'oge afọ ime, n'oge na mgbe a wachara ya ahụ, yana ọrịa ndị na-esochi ahụ na-enwe mmetụta ọjọọ n'ọrịa shuga.

Nsonaazụ Protafan NI Penfill

Ihe omume ọjọọ na - achọpụta na ndị ọrịa n'oge ọgwụgwọ ahụ bụ ihe riri ahụ ma ọ bụrụ na ha na - eme ihe metụtara ọgwụ ọgwụ. N'ime nsogbu ndị a na-enwekarị nsogbu, hypoglycemia na-ama ama. Na-aputa ihe n'ihi ekwenyeghi iwu nke insulin.

Na nnukwu hypoglycemia, mwepu nke onwe, ihe ọdịdọ, ọrụ ụbụrụ na-akpata, na mgbe ụfọdụ ọnwụ, enwere ike. N'ọnọdụ ụfọdụ, mmebi nke metabolism metabolism.

N'akụkụ nke sistem na-alụ ọgụ ga-ekwe omume: ihe ọkụ ọkụ, urticaria, ọsụsọ, itching, mkpụmkpụ ume, nkụchi obi, mgbada ọbara, mbelata nke mmụọ.

N'akụkụ nke usoro ahụ ji alụso ọrịa ọgụ, nsonaazụ na-adịghị mma ga-ekwe omume: ihe ọkụ ọkụ, urticaria, itching.

Sistemmuo ụjọ nọkwa n’ihe ize ndụ. N'ọnọdụ ndị na-adịghị ahụkebe, akwara neuropathy na-apụta.

Ntụziaka pụrụ iche

Ọdịnaya ahọpụtara n'ụzọ na-ekwesịghị ekwesị ma ọ bụ ịkwụsị usoro ọgwụgwọ na-akpata hyperglycemia. Mgbaàmà nke mbu bidoro igosipụta n’ime awa ole na ole ma ọ bụ ụbọchị ole na ole. Ọ bụrụ na enyeghị enyemaka n'oge, ihe egwu nke ịrịa ọrịa mamịrị ketoacidosis, nke na-emetụta ndụ mmadụ na-abawanye.

Site na ọrịa ọnya na-efe efe nke na-egosipụta ahụ ọkụ ma ọ bụ ọrịa na-efe efe, ịchọrọ insulin na ndị ọrịa na-abawanye. Ọ bụrụ na ọ dị mkpa, gbanwee usoro ọgwụgwọ ọ nwere ike idozi ya na oge ntụtụ mbụ ma ọ bụ jiri ọgwụgwọ ọzọ.

Jiri na agadi

Ndị ọrịa ruru afọ 65 anaghị enwe mmachi n’ị takingụ ọgwụ. Mgbe ha ruru afọ a, ndị ọrịa kwesịrị ịnọ n'okpuru nlekọta nke dọkịta ma tụlee ihe ndị metụtara ya.

Enwere ike iji ya maka ụmụaka na-erubeghị afọ 18. Usoro ogwu a ka edobere iche n’otu n’otu nyocha. A na-ejikarị ụdị diluted.

Jiri n'oge ime na lactation

Ejiri n'oge ime, dị ka ọ bụghị gafere Plasenta. Ọ bụrụ na a naghị agwọ ọrịa shuga n’oge a na-amụ nwa, ihe ize ndụ nke nwa ebu n’afọ na-abawanye.

Ọrịa hypoglycemia na-apụta na usoro ọgwụgwọ ahọpụtaghị nke ọma, nke na-abawanye ohere nke ntụpọ na nwatakịrị ahụ na-eyi ya egwu ọnwụ intrauterine. N’oge mbụ, ọ dị mkpa inweta insulin n’okpuru, na n ’2 na 3 ọ na-abawanye. Mgbe inyechara ya, mkpa ịchọrọ insulin na-abụ otu.

Ọgwụ ahụ adịghị ize ndụ mgbe ị na-enye nwa ara. N'ọnọdụ ụfọdụ, achọrọ mgbanwe maka usoro ịgba ọgwụ ma ọ bụ usoro nri.

Nwepu nke Protafan NI Penfill

Achọpụtabeghi usoro ọgwụ mmịnye ọbara riri. Maka onye ọrịa ọ bụla, na-eburu n'uche etu usoro ọrịa ahụ dị, enwere nnukwu ọgwụ, nke na-eduga n'ọdịdị hyperglycemia.

Site na ọnọdụ hypoglycemia dị nwayọ, onye ọrịa ahụ nwere ike ịnagide ya n'onwe ya site na iri nri dị ụtọ na nri nwere nnukwu carbohydrates.

Ọ dịghị afụ ụfụ ị sweụ mmanya, kuki, ihe ọ fruitụ fruitụ mkpụrụ osisi ma ọ bụ naanị obere shuga.

N'ọdị siri ike (amaghị ihe), a na-agbanye mgbanye glucose (40%) na akwara, 0,5-1 mg nke glucagon n’ahụ ma ọ bụ akwara. Mgbe a na-eme ka mmadụ mara ihe, iji zere ihe ize ndụ nke ịlaghachi azụ, ha na-enye nri nri carb.

Ọnọdụ nchekwa maka ọgwụ

Ekwesịrị idobe ọgwụ a na ebe dị jụụ na ọchịchịrị na okpomọkụ nke + 2 ... + 8 Celsius C (enwere ike itinye ya na friji, mana ọ bụghị friza). Ọ bụghị n'okpuru kefriza. Ekwesịrị idobe katọn ahụ na nkwakọ ngwaahịa ya iji chebe ya pụọ na ìhè anyanwụ.

A na-echekwa katalọgụ ahụ na 30 Celsius C karịa ụbọchị 7. Echekwala na friji. Machibido ohere ụmụaka.

Emeputa

NOVO NORDISK, A / S, Denmark

Protafan insulin: nkọwa, nyocha, ọnụahịa

Ihe nyocha insulin na-ahụ maka mmadụ

Svetlana, onye gbara afọ 32, Nizhny Novgorod: “N'oge imem, eji m Levemir, mana hypoglycemia na-egosipụta mgbe niile. Dọkịta na-aga ahụ tụrụ aro ka ịgbanye inje nke Protafan NM Penfill. Ọnọdụ ahụ agbagbuola, mmetụta ndị ọzọ n'oge afọ ime ahụ na mgbe a hụpụtaghị ya. "

Konstantin, dị afọ 47, Voronezh: “Kemgbe afọ 10, amalitewo m ọrịa shuga mellitus. N'oge niile m enweghị ike ịhọtara onwe m ọgwụ kwesịrị ekwesị maka ijigide glucose n'ọbara. Naanị ọnwa isii gara aga, azụrụ m ọgwụ mgbochi Protafan NM Penfill ma enwere m obi ụtọ na nsonaazụ ya. Ihe isi ike na nsogbu niile na-apụta na mbụ anaghị eme onwe ha obi ọzọ. Ọnụ ahịa dị ọnụ. ”

Valeria, onye dị afọ 25, St. Petersburg: “Anọwo m arịa ọrịa shuga kemgbe m bụ nwata. Anwara m ihe karịrị ọgwụ 7, ọ nweghịkwa afọ ojuju. Ọgwụ ikpeazụ m zụrụ dịka dọkịta m gwara ya bụ nkwusioru Protafan NM Penfill.

Ruo n'oge na-adịbeghị anya, enwere m obi abụọ banyere ịdị irè ya ma enweghị m olileanya karịsịa na ọnọdụ ahụ ga-agbanwe. Mana ọ chọpụtara na ọdịdị hypoglycemia kwụsịrị inye ya nsogbu, ahụike ahụike zuru oke. Ana m azụta na karama.

Ngwaahịa a dịkwa mma iji ma ọ dịkwa ọnụ ala. ”

Protafan - ntuziaka zuru ezu maka ojiji

Ọrịa shuga mellitus na-ezo aka na ọrịa ọrịa na-adịghị ala ala na-emetụta akụkụ ahụ niile. A na - ejikọta usoro nke mmepe dị na ụkọ insulin nke hormone, nke na - ahụ maka itinye glucose site na mkpụrụ ndụ. N'ihi nke a, enwere nguzozi na metabolism, ọkwa glucose dị n'ọbara na-ebili. Usoro ọgwụgwọ nke ọrịa shuga mellitus na-agbago ruo mgbe ọ ga-edochi homonụ dị ogologo ndụ.

Azoputala uzo nile siri puta. Otu n’ime ha bụ Protafan. Ntụziaka maka iji ya nwere ozi zuru oke dị mkpa maka iji nnwere onwe nke ọgwụ a dị mkpa.

Ngwakọta na ụdị ntọhapụ

Ihe na-arụ ọrụ bụ insulin mmadụ, nke teknụzụ sitere na mkpụrụ ndụ ihe mepụtara. Dị na ọtụtụ usoro onunu ogwu:

"Protafan NM": nke a bụ nkwusioru na vials, kwa 10 ml, insulin concentrated nke 100 IU / ml. Ihe ngwugwu nwere otu karama.
Protafan NM Penfill: katriki nke nwere 3 ml (100 IU / ml) nke ọ bụla. N'otu ọnya - katriiti 5, na ngwugwu - 1 ọnya.

Ndị ọkachamara: mmiri maka injection, glycerin (glycerol), phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, metacresol, sodium hydroxide na / ma ọ bụ hydrochloric acid (iji dozie pH), zinc chloride.

Cipleskpụrụ nke iji Protafan

A na-eji ọgwụ ahụ eme ihe maka ụdị ọrịa ọ bụla. N’ime Idị nke I, a na-amalite ya ngwa ngwa, n’ụdị nke II, a na-egosi Protafan n’ọnọdụ arụmọrụ sitere na ụdị sulfonylurea, n’oge afọ ime, n’oge na mgbe ọ rụsịrị ọrụ, n’ihu ọrịa ndị na-agbakọ agbakọ na-agbagha usoro nke ọrịa shuga mellitus.

Ọgwụ mlọ Ọgwụ

A na - edekọ mmalite mmalite nke ihe omume 1.5 awa mgbe nchịkwa subcutaneous gasịrị. Arụmọrụ kachasị - mgbe awa 4-12 gasịrị. Oge ngụkọta nke awa 24.

Pharmdị ọgwụ pharmacokinetics ahụ na-ekpebi usoro izugbe nke eji "Protafan":

Mellitus na-arịa insulin na-adabere - dị ka ihe bụ isi maka ya na insulins na-adị mkpụmkpụ.
A na-anabata ọrịa shuga na-arịa insulin na-abụghị insulin - monotherapy nwere ihe nnọchianya a, yana ngwakọta na ọgwụ ndị na-eme ngwa ngwa.

Ọ bụrụ na eji ọgwụ ahụ eme ihe dị ka ọgwụgwọ anụ, ọ bụ ọnụ tupu nri. Na usoro eji arụ ọrụ, a na-ahụ maka otu ugboro n'ụbọchị (n'ụtụtụ ma ọ bụ na mgbede).

Ajuju ajuju nke Protafan nwere ike inye azịza na-adịghị mma; nke a bụ ihe ndabere maka ọgwụgwọ ọ bụla enweghị ike ịnye ya.

Ofzọ nke ngwa

Ọgwụ a na-abanye n’ahụ. Ebe ọdịnala bụ mpaghara hip. A na-anabata inje na mpaghara nke mgbidi ime, isi, na akwara aka. Ekwesịrị ịhọrọ saịtị ntụgharị ahụ iji gbochie mmepe nke lipodystrophy. Ọ dị mkpa ịdọrọ ikiri akpụkpọ ahụ nke ọma iji gbochie insulin nke anụ ahụ na - egbochi insulin.

IKWU! Amachibidoro nchịkwa insulin na ịkwadebe ya na ọnọdụ ọ bụla.

Ofzọ iji mkpịsị sirinji maka insulin "Protafan"

Ogologo oge iji aka ya mee ihe n ’icho ihe icho ichochu were mee ka usoro a di nma. Maka nke a, edepụtara mkpịsị mkpụrụ sirinji, nke a na-ejizi katriji Prota emezi.

Onye ọ bụla na-arịa ọrịa shuga kwesịrị ịma ntuziaka maka ojiji ya site n'obi:

Tupu ijuputa katriki, lelee nkwakọ ngwaahịa iji jide n'aka na usoro ịse ahụ ziri ezi.
Gbalịsie ike nyochaa katki ahụ n'onwe ya: ọ bụrụ na ọ nwere ihe ọ bụla mebiri emebi ma ọ bụ oghere dị n'etiti teepu ọcha na pịpị rọba, mgbe ahụ ejighị nkwakọ ngwaahịa a.
A na-eji akpụkpọ ahụ roba na-eji ọgwụ na-ehicha ọrịa site na iji swab owu.
Tupu ị wụnye kadi ahụ, a na-adọ mmiri. Iji mee nke a, gbanwee ọnọdụ ahụ ka bọọlụ iko ahụ wee banye n'otu nsọtụ gaa na nke ọzọ opekata mpe 20. Mgbe nke a gasị, mmiri mmiri kwesịrị iburu oke gbaa.
Naanị katalọgụ ndị ahụ nwere opekata mpe insulin iri na abụọ kwesiri ka agwakọta dịka usoro a kọwara n’elu. Nke a bụ nke kacha nta karịa maka ejupụta n'ime mkpụrụ sirinji.
Mgbe etinye ya n'okpuru anụ ahụ, agịga ahụ kwesịrị ịnọ ebe ahụ opekata mpe isii. Naanị na nke a, a ga-abanye dose ahụ kpamkpam.
Mgbe ogwu ogbugba nke ọ bụla, agịpụrụ agịga ahụ na sirinji. Nke a na - egbochi mmiri mmiri na - ejideghi ya, na - eduga ngbanwe nke usoro onodu ọzọ.

Protafan: ntuziaka maka ojiji, ọnụahịa, nyocha na analogues

Enwere ọtụtụ ọgwụ na ahịa ọgwụ ndị ụlọ ọrụ na-emepụta ọgwụ a ma ama na-emepụta, mana ịchọta ụzọ kachasị mma maka ndị ọrịa ọ bụla nwere ọrịa shuga siri ezigbo ike. Dabere na ntuziaka maka ojiji, "Protafan NM" nwere ezigbo akụ ma dị ọnụ ala. Tụlee ọgwụ a na nkọwa ndị ọzọ.

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

Ọgwụ bụ nkwusioru ọcha. Mgbe echekwara, ọ na - agbanye mmiri ọcha na - enweghị ụcha. Nke a apụtaghị na ọgwụ ahụ arịala njọ - na-ama jijiji, nkwụghachi ahụ laghachiri na steeti ya bu ụzọ.

insulin-isophan na mkpokọta nke 100 IU kwa 1 ml,
zinc chloride
glycerin (glycerol),
metacresol
phenol
ikuku sodium hydrogen phosphate na-ada mmiri,
protamine sulfate,
sodium hydroxide na / ma ọ bụ hydrochloric acid,
mmiri maka ịgba ntụtụ.

A di ya na usoro aka nri (iberibe 5 kwa nbudata) ma obu na 10 ml vials.

Ndị na-emepụta INN

Aha mba ndị na - abụghị nke aka bụ insulin-isophan (injinị mmadụ sitere na mkpụrụ ndụ).

Nke Novo Nordisk, Bugswerd, Denmark rụpụtara. Enwere ụlọ ọrụ nnọchiteanya na Russia.

Ihe dị iche site na 400 rubles (maka otu karama 10 ml) ruo 900 rubles (maka katriiki). Enwere ike ịchọta ụlọ ahịa ọgwụ dị n'ịntanetị na ọnụahịa dị ala.

ụdị 1 na ụdị ọrịa shuga 2
oria oria abuo n’ime ndi nwanyi di ime.

Ntụziaka maka ojiji (usoro)

A na-ekpebi ya n’otu n’otu dabere na insulin chọrọ ahụ. Edere ya na dibia bekee dika odi nyocha nke nyocha. Ihe dị ka ọkara bụ 0,5 ruo 1 IU / kg kwa ụbọchị.

A na-eji ya maka naanị nchịkwa okpuru ala. Enwere ike iji ya mee ihe dị ka monotherapy, yana yana ọgwụ ndị ọzọ. Ọtụtụ mgbe, a na-eme ọgwụ na apata ụkwụ, ubu, isi ma ọ bụ n'afọ. Ọ dị mkpa ka saịtị ntanetị ọzọ iji gbochie mmepe nke lipodystrophy. Ya mere, n’ime otu ọnwa, ịgaghị agwọ ọgwụ ahụ ugboro abụọ otu ebe.

Ime na lactation

Enwere ike iji ya n'oge oge ịgba akwụkwọ na n'oge a na-enye nwa ara, ebe ọ bụ na ọ gaghị abụ ihe iyi egwu maka mmepe nwa ebu n'afọ ma ọ banyeghị na mmiri ara.

Nwanyị chọrọ nrụpụta usoro ọgwụgwọ oge niile, n'ihi na n'oge afọ ime, mkpa maka insulin nwere ike gbanwee. Yabụ, ọ na-agbadata na ọkara nke mbụ ma na-abawanye na-esote.

Ya mere, ị kwesịrị ịdị na-enyocha ọnọdụ gị mgbe niile ma gbochie hypoglycemia nke na-emerụ nwata ahụ.

Usoro na ọnọdụ nchekwa

Ndụ shelf - afọ 2.5, mgbe ọ gwụsịrị ụbọchị ọ na-ewepu.

A na-echekwa ya n'ebe kpọrọ nkụ, ọchịchịrị, na refrjiraeto na okpomọkụ nke 2 ruo 8 Celsius. Emela ifriizi! Mgbe emepechara ngwungwu ahụ, ndu nchekwa ahụ bụ izu isii n’arụghị mmiri ogo 30.

A ga-echebe ya site na ụmụaka.

Tụnyere ihe analogues

Enwere otutu analogues nke ogwu a.

Aha, ihe eji arụ ọrụ	Emeputa	Uru na Cons	Ọnụahịa, tee.
Humulin, insulin insulin.	"Eli Lilly", USA, "BIOTON S.A.", Poland.	Enwere ike iji ya: enwere ike iji ya n'oge afọ ime yana na ụmụaka na-erubeghị afọ 18.

Cons: ọnụahịa ahụ dị elu, jiri mkpachapụ anya na ndị mmadụ karịrị afọ 65.

site na 500 (maka karama 10 ml), site na 1100 (maka katriiki). "Biosulin", insulin-isophan.Pharmstandard-Ufavita, Russia.Uru: ọ bụghị ọtụtụ nsonaazụ.

Cons: achọrọ nlekọta dọkịta mgbe ejiri ya na ndị ọrịa agadi, ọ ga-ewe ogologo oge ichere maka mmalite nke usoro.

site na 500 (karama 10 ml), site na 900 (katrized maka mkpịsị sirinji). Levemir, insulin detemir.Novo Nordisk, Denmark.Uru: ọ na-adị ogologo oge, enweghị protamine, nke nwere ike ibute ihe nfụkasị.

Cons: dị oke ọnụ, anaghị atụ aro maka ụmụaka na-erubeghị afọ isii.

site na 1800 (mkpụrụedemede sirinji).

Iji dochie otu ọgwụ na ọgwụ ọzọ ga-ekwe omume naanị site na dọkịta. Amachibidoro ị medicationụ onwe gị ọgwụ!

Insulin Protafan: ntuziaka maka idochi ya na ole

Usoro ọgwụgwọ shuga n'oge a gụnyere iji ụdị insulin abụọ: ikpuchi mkpa ndị dị mkpa na ịkwụ ụgwọ shuga mgbe ị risịrị. N'ime ọgwụ ndị na-eme ka ọ dị ala ma ọ bụ nke dị n'etiti, akara mbụ dị na ọkwa bụ nke Protafan insulin, òkè ahịa ya bụ ihe dịka 30%.

Onye rụpụtara ya, ụlọ ọrụ Novo Nordisk, bụ onye ama ama n'ụwa niile n'ọgụ megide ọrịa shuga. Site na nyocha ha, insulin pụtara na ebe dị anya na 1950 na-arụ ọrụ ogologo oge, nke mere ka o kwe omume ime ka ndụ ndị ọrịa dị mfe. Protafan nwere akwa nhicha dị elu, kwụsiri ike ma nwee ike ịkọpụta ya.

Ntụziaka dị mkpirikpi

A na-emepụta Protafan n'ụzọ ndụ. A na-ewebata DNA dị mkpa maka njikọ insulin n'ime microorganisms nke yist, emesịa ha malitere imepụta proinsulin. Insulin enwetara mgbe ọgwụgwọ enzymatic gasịrị bụ mmadụ.

Iji mee ka ihe omume ya dịkwuo ogologo, a na-agwakọta homonụ ahụ na protamine, a na-akụkwa ya site na iji teknụzụ pụrụ iche. A na-eji ọgwụ mepụtara n'ụzọ dị otú a na-egosipụta ya mgbe niile, ị nwere ike ijide n'aka na ngbanwe nke karama ahụ agaghị emetụta shuga ọbara.

Maka ndị ọrịa, nke a bụ ihe dị mkpa: ihe ole na ole na-emetụta ọrụ insulin, ụgwọ dị mma maka ọrịa shuga ga-abụ.

Protafan HM dị na iko vials nwere usoro 10 ml. N’ụdị a, ọgwụ ndị ụlọ ọgwụ na ndị ọrịa shuga na-anara insulin. N'ime igbe kaadiboodu 1 kalama na ntuziaka maka ojiji.

Protafan NM Penfill bụ 3m katridges a ga-etinye na NovoPen 4 pensụl pensụl (usoro nke 1) ma ọ bụ NovoPen Echo (nkeji 0,5). Maka ịdị mma nke ịgwakọta na katalọgụ ọ bụla iko bọọlụ. Ihe ngwugwu ahụ nwere katọnges na ntuziaka 5.

Mbelata shuga ọbara site na ibuga ya na nsị anụ ahụ, na-eme ka njikọ glycogen nwee akwara na umeji. Ọ na - akpali nguzobe nke protein na abụba, yabụ, na - enye aka n'ịba ụba.

A na-eji ya maka ịnọgide na-enwe shuga na-ebu ọnụ nkịtị: n'abalị na n'etiti nri. Enweghi ike iji protafan mezie glycemia, a na-ezube insulins dị mkpa maka ebumnuche ndị a.

Mkpa insulin na-abawanye na nrụgide akwara, mmerụ ahụ na nke uche, mbufụt, na ọrịa na-efe efe. Of ofụ mmanya na-egbu egbu n'ime ọrịa shuga abụghị ihe a na-achọghị, n'ihi na ọ na-eme ka uru nke ọrịa ahụ dịkwuo elu ma nwee ike ịkpasu hypoglycemia siri ike.

Imeghari dose mgbe ị na-a certainụ ọgwụ ụfọdụ. Mụbaa - site na iji ọgwụ mgbarụ na ọgwụ ọgwụ homonụ. Mbelata - n'ihe banyere otu oge nchịkwa na mbadamba shuga dị ala, tetracycline, aspirin, ọgwụ antihypertensive site na otu nke ndị na - anabata ndị na - anabata ụdọ AT1 na ndị na - egbochi ACE.

Mmetụta dị njọ nke insulin ọ bụla bụ hypoglycemia. Mgbe ị na-eji ọgwụ ọgwụ NPH, ihe ize ndụ nke ịda shuga n'abalị bụ nke kachasị elu, ebe ọ bụ na ha nwere oke ọrụ.

Nocturnal hypoglycemia kacha dị ize ndụ na ọrịa shuga mellitus, ebe onye ọrịa ahụ enweghị ike ịchọpụta ma kpochapụ ya n'onwe ha.

Obere shuga n’abali bụ nsonaazụ nke ahọpụtara nke ọma ma ọ bụ njirimara metabolic nke mmadụ.

N'ihe na-erughị 1% nke ndị ọrịa mamịrị, insta protafan na-akpata mmeghachi omume nfụkasị mpaghara dị nro n'ụdị ọnya, itching, ọria na ebe injection. Ihe puru iche nke nnukwu ahu anataghi emeputara na erughi 0.01%. Mgbanwe na abụba subcutaneous, lipodystrophy, nwekwara ike ịdaba. Ihe ize ndụ ha dị elu ma ọ bụrụ na esoghị usoro ịgba ntụtụ ahụ.

Amachibidoro Protafan iji ndị ọrịa nwere ọrịa akpịrị ma ọ bụ ede ede Quincke maka insulin. Dịka dochie anya, ọ ka mma iji abụghị NPH insulins nwere ụdị ihe mejupụtara, kama insulin analogues - Lantus ma ọ bụ Levemir.

Ndị ọrịa mamịrị ekwesịghị iji Protafan mee ihe n'ịrụ ọrụ hypoglycemia, ma ọ bụ ọ bụrụ na-ehichapụ ihe mgbaàmà ya. Achọpụtara na insulin analogues na nke a dị nchebe karịa.

Nkọwa	Protafan, dị ka ihe NPH niile, na-ekpughere ya na vial. N'okpuru ebe enwere ntụpọ ọcha, n’elu - mmiri mmiri translucent. Mgbe agwakọta, ngwakọta ahụ dum na-acha ọcha. Ta ụta nke ihe arụ ọrụ bụ 100 nkeji kwa mililita.
Dị Mwepụta
Ngwakọta	Ngwakọta ọrụ na-arụ ọrụ bụ insulin-isophan, ihe inyeaka: mmiri, sọlfọ protamine iji mee ka ogologo oge nke ihe, phenol, metacresol na zinc ion dị ka ihe nchekwa, ihe maka idozi acidity nke ihe ngwọta.
Ihe omume
Ihe na-egosi	Ọrịa shuga dị n'ime ndị ọrịa chọrọ ọgwụ insulin, n'agbanyeghị afọ ole ọ dị. Site na oria 1 - site na mmalite nke nsogbu nke carbohydrate, ya na ụdị nke 2 - mgbe ọgwụ ịbelata shuga na nri anaghị arụ ọrụ nke ọma, na haemoglobin glycated karịrị 9%. Afọ ime na ụmụ nwanyị dị ime.
Nhọrọ onunu ogwu	Ntụziaka ahụ enweghị ọgwụ a tụrụ aro ya, ebe ego insulin chọrọ maka ndị ọrịa mamịrị dị iche. A na-agbakọ ya na ndabere nke data glycemia na-ebu ọnụ. A họọrọ usoro insulin maka nchịkwa ụtụtụ na nke mgbede - ngụkọta oge nke insulin maka ụdị abụọ ahụ.
Dose ukpụhọde
Nsonaazụ
Ihe ngbanwe
Nchekwa	Nwee nchedo site na ọkụ, okpomoku na ekpomoku (> 30 Celsius C). Ekwesịrị idobe ya na igbe, a ga-eji okpu chekwaa insulin na mkpịsị mkpụrụ ogwu. Na ihu igwe na-ekpo ọkụ, a na-eji ngwaọrụ nkwụghachi pụrụ iche na-ebugharị Protafan. Ọnọdụ kachasị mma maka nchekwa ogologo oge (ruo izu 30) bụ shelf ma ọ bụ ọnụ ụzọ friji. N'ime ụlọ dị na ụlọ, Protafan na vial ya bidoro izu isii.

Oge ihe omume

Ọnụego ntinye nke Protafan sitere na anụ ahụ dị n'okpuru ala n'ime ọbara n'ọrịa na ndị ọrịa nwere ọrịa shuga dị iche, yabụ agaghị ekwe omume ịkọ n'ụzọ ziri ezi mgbe insulin malitere ịrụ ọrụ. Nkezi data:

Site na ntụtụ gaa na ọdịdị nke homonụ n’ime ọbara, ihe dịka awa 1.5 gafere.
Protafan nwere ọrụ kachasị elu, n'ọtụtụ ndị ọrịa mamịrị ọ na - apụta na awa anọ 4 site n'oge nchịkwa.
Oge ngụkọta oge ana - eme ihe ruru awa iri abụọ na anọ. N'okwu a, ndabere nke oge ọrụ na dose achọrọ. Site na ntinye nke nkeji iri nke protafan insulin, a ga-ahụta mbelata mmịpụta ihe dịka elekere 14, nkeji 20 maka ihe dịka awa 18.

Usoro usoro ịgba ọgwụ mgbochi

N'ọtụtụ ikpe na-arịa ọrịa shuga, nchịkwa abụọ nke Protafan ezuru: n'ụtụtụ na tupu ụra. Jectiontụtụ mgbede kwesịrị iji zuru ezu iji nwee glycemia n'abalị niile.

Ndewo Aha m bụ Alla Viktorovna, enweghịzi m ọrịa shuga! O were m nanị ụbọchị 30 na 147 rubles.iweghachite shuga n’agha ka ọ ghara ịdabere n’arụ ọgwụ na-abaghị uru nke nwere ọtụtụ nsonaazụ.

>>You nwere ike gụọ akụkọ m nke ọma ebe a.

Ntuziaka maka usoro ziri ezi:

shuga n’ụtụtụ bụ otu ihe n’oge ụra
enweghi hypoglycemia n'abalị.

Ọtụtụ mgbe, shuga ọbara na-ebili mgbe elekere 3 nke ụtụtụ gasịrị, mgbe mmepụta nke homonụ na-enwekarị ọrụ, na mmetụta nke insulin na-ebelata.

Ọ bụrụ na ọnụ ọgụgụ kachasị elu nke Protafan ga-akwụsị na mbụ, ọ ga-ekwe omume nsogbu ahụ ike: hypoglycemia na-amaghị n'abalị na nnukwu shuga n'ụtụtụ. Iji zere ya, ịkwesịrị ịlee ọkwa shuga kwa oge na elekere 12 na 3.

Enwere ike ịgbanwe oge mgbede mgbede, na-agbaso atụmatụ nke ọgwụ.

Ihe omume nke obere doses

Site n'ọrịa shuga 2dị nke abụọ, ọrịa shuga nke ụmụ nwanyị dị ime, na ụmụaka, na ndị okenye nọ na nri nwere obere carb, mkpa nke insulin nke NPH nwere ike ịbụ obere. Site na obere obere ọgwụ (ruo 7 nkeji), oge nke ihe Protafan nwere ike ịbụ naanị awa 8. Nke a pụtara na inpa abụọ ahụ ntuziaka a na-enye agaghị ezu, n'etiti etiti shuga n'ọbara ga-amụba.

Enwere ike izere nke a site na ịgbanye insulin insulin ugboro atọ kwa awa 8 ọ bụla: a na-enye ntụtụ nke mbụ ozugbo ịmụrụ anya, nke abụọ n’oge nri ehihie na insulin mkpụmkpụ, nke atọ, nke kachasị ukwuu, tupu ị lakpuo ụra.

Nyocha banyere ọrịa mamịrị, ọ bụghị mmadụ niile na-eme nke ọma n’ị nweta ezigbo ụgwọ maka ọrịa shuga n'ụzọ dị otu a. Mgbe ụfọdụ ọgwụ ụra abalị na-akwụsị ịrụ ọrụ tupu ịmụrụ anya, yana shuga n'ụtụtụ dị elu. Thebawanye dose ahụ na-eduga n'ịba ụba insulin na hypoglycemia. Naanị otu ụzọ enwere ike isi na ya pụta bụ ịgbaga insulin analogues na ogologo oge ị ga-eme.

Ihe iri nri

Ndị ọrịa shuga na insulin na-abụkarị ndị a na-akọ ka ọ bụrụ insulin na nke dị mkpụmkpụ.Short dị mkpa iji belata glucose na-abanye n'ọbara nke nri. A na-ejikwa ya iji dozie glycemia. Yana Protafan ọ ka mma iji obere nkwadebe nke otu emeputa ihe - Actrapid, nke dịkwa na vials na katridges maka mkpịsị mkpụrụ sirinji.

Oge nchịkwa nke insulin Protafan anaghị adabere na nri n'ụzọ ọ bụla, ihe dị ka otu oge n'etiti nsị zuru ezu. Ozugbo ịhọrọ oge dabara adaba, ịkwesịrị ịgbaso ya mgbe niile.

Ọ bụrụ na ọ dabara na nri, enwere ike ịkwụ ụgwọ Protafan na insulin dị mkpụmkpụ.

N'otu oge ịgwakọta ha n'otu sirinji bụ ihe a na-achọghị, ebe okwesiri imehie uzo na iwelata nwayọ n’ọkpụkpụ hormone.

Ikike dị ukwuu

Na shuga mellitus, ịkwesịrị ịbanye insulin dị ka a chọrọ iji mee ka glucose dị ọcha. Ntụziaka maka ijibebeghị ọgwụ kacha ike. Ọ bụrụ na ego ziri ezi nke protafan insulin na-eto, nke a nwere ike igosipụta nguzo insulin. Na nsogbu a, ị ga-agakwuru dọkịta gị. Ọ bụrụ na ọ dị mkpa, ọ ga-edenye ọgwụ na-eme ka ihe ahụ na - eto homonụ.

Iji Oge ime

Ọ bụrụ na enwere ọrịa shuga, ọ gaghị ekwe omume ị nweta ọrịa nkịtị nkịtị naanị site na nri, a na-enye ndị ọrịa ọgwụ insulin. A na-ahọrọ ọgwụ na ọgwụ ya karịsịa nke ọma, ebe ọ bụ na hypo- na hyperglycemia na-amụba ohere nke imerụ nwata ahụ. Anabataghị insulin Protafan maka oge afọ ime, mana n'ọtụtụ oge, ogologo oge analogues ga-adị irè karị.

Ọ na-emekpa gị ọbara mgbali elu? Knowmara na ọbara mgbali elu na-eduga ọgụ obi na ọrịa strok? Nọmalị nrụgide gị na ... Echiche na nzaghachi banyere usoro a na-agụ ebe a >>

Ọ bụrụ na ime tụụrụ ime n'ọrịa shuga nke 1, nwanyị ahụ wee kwụọ ụgwọ ọrịa ahụ Protafan, ọgwụ agbanweghị ya.

Breastfeu ara ara na usoro insulin. Protafan agaghị emerụ ahụike nwata ahụ. Insulin na-abanye n'ime mmiri ara ehi na obere ntakịrị, mgbe nke ahụ gasịkwara nke ahụ, ọ na-agbazekwa na usoro nri nke nwa ahụ, dịka protein ọ bụla.

Protafan analogues, na-agbanye insulin ọzọ

Analogues zuru oke nke Protafan NM nwere otu ihe ahụ na-arụ ọrụ na oge ọrụ dị nso bụ:

Humulin NPH, USA - onye asọmpi kachasị, nwere ike ahịa karịa karịa 27%,
Insuman Bazal, France,
Biosulin N, RF,
Rinsulin NPH, RF.

Site na echiche nke ọgwụ, ngbanwe nke Protafan gaa na ọgwụ ọgwụ NPH ọzọ abụghị ngbanwe insulin ọzọ, yana na Ntụziaka naanị naanị ihe ndị nọ n'ọrụ ka egosiri, ọ bụghị akara aha akọwapụtara.

Na omume, ndochi dị otú ahụ nwere ike ọ bụghị naanị igbochi njikwa glycemic nwa oge ma chọọ ndozi nke dose, kamakwa na-akpasu oke nfụkasị.

Ọ bụrụ na haemoglobin glycated dị nkịtị na hypoglycemia dị ụkọ, ọ gaghị adị mma ka ị jụ insulin Protafan.

Ọdịiche nke analogues insulin

Ogologo insulin analogues, dị ka Lantus na Tujeo, enweghị ọnụ ọgụgụ kasị elu, a na-anabata ya karịa ka o nwere ike ibute ọrịa. Ọ bụrụ na onye na-arịa ọrịa shuga enweghị ọrịa hypoglycemia nke ehihie ma ọ bụ na-egbochi shuga n'ihi ihe ụfọdụ, a ga-eji Protafan dochie anya insulins oge ọhụụ.

Ihe ọghọm ha dị ukwuu bụ ụgwọ ha dị elu. Ọnụahịa nke Protafan bụ ihe ruru 400 rubles. maka otu karama na 950 maka mbukota ogwe maka mkpịsị mkpụrụ sirinji. Insulin analogues nwere ihe kariri ugboro ato.

Gbalia imuta! Ì chere na ọgwụ na insulin bụ nanị ụzọ iji gbochie shuga? Ọ bụghị eziokwu! Nwere ike ịchọpụta nke a n'onwe gị site na ịmalite iji ... gụkwuo >>