Ntụziaka maka iji ọgwụ ahụ Torvacard na ọgwụ analogues ya

N’eme ọgwụgwọ ọrịa shuga, ọ bụghị naanị ọgwụ ndị na-emetụta ókè glucose dị n’ọbara na-eji.

Na mgbakwunye na ndị a, dọkịta gị nwere ike ịde ọgwụ ndị na-enyere aka belata cholesterol.

Otu ọgwụ dị otú ahụ bụ Torvacard. Needkwesịrị ịghọta otú ọ ga-esi bara uru maka ndị ọrịa mamịrị na otu esi eji ya.

Ozi izugbe, ihe mejupụtara, ụdị ntọhapụ

Statin cholesterol mgbochi

Ngwá ọrụ a bụ otu n'ime ihe oyiyi - ọgwụ iji belata cholesterol ọbara. Isi ọrụ ya bụ belata nsị nke abụba dị n'ahụ.

Ejiri ya rụọ ọrụ nke ọma iji gbochie ma lụ ọgụ atherosclerosis. Na mgbakwunye, Torvacard nwere ike belata oke shuga dị n'ọbara, nke bara uru maka ndị ọrịa nwere nsogbu ibute ọrịa shuga.

Ndabere nke ọgwụ bụ ihe Atorvastatin. Ya na ngwakọta ndị ọzọ na - eme ka enwee ebumnuche.

A na-emepụta ya na Czech Republic. Nwere ike ịzụta ọgwụ naanị n'ụdị mbadamba nkume. Iji mee nke a, ịchọrọ ọgwụ n’aka dọkịta gị.

Akụkụ ahụ nọ n'ọrụ nwere mmetụta dị ukwuu n'ọnọdụ onye ọrịa, yabụ ị -ụ ọgwụ onwe ya na ya anabataghị. Gbalia inweta uzo ntuziaka.

A na-ere ọgwụ a n'ụdị ọgwụ. Ngwakọta ha na-arụ ọrụ bụ Atorvastatin, ọnụego ya na nke ọ bụla nwere ike ịbụ 10, 20 ma ọ bụ 40 mg.

Ihe ntinye aka inye aka na ntinye aka na ntinye aka nke Atorvastatin:

• magnesium oxide
• microcrystalline cellulose,
• sịlịkọn dioxide
• sodium croscarmellose,
• lactose monohydrate,
• stereị magnesium,
• hydroxypropyl cellulose,
• ntụ ntụ talcum
• macrogol
• titanium dioxide
• hypromellose.

Mbadamba nkume ndị ahụ nwere agba gbara gburugburu na agba ọcha (ma ọ bụ nke na-acha ọcha). A na-etinye ha na blisters nke 10 PC. Enwere ike idozi ngwugwu ahụ na blisters 3 ma ọ bụ 9.

Pharmacology na pharmacokinetics

Ihe atorvastatin bụ igbochi enzyme nke na - eme cholesterol. N'ihi nke a, a na-ebelata ego cholesterol.

Ndị na-anabata cholesterol na-amalite ịrụsi ọrụ ike, n'ihi nke a na - erepịa ihe dị n'ime ọbara ngwa ngwa.

Nke a na - egbochi nguzobe atherosclerotic na arịa. Ọzọkwa, n'okpuru nduzi nke Atorvastatin, nchịkọta nke triglycerides na glucose na-ebelata.

Torvacard nwere mmetụta ọsọ ọsọ. Mmetụta nke akụkụ ya nọ n'ọrụ na-erute ike ya kachasị elu mgbe awa 1-2 gachara. Atorvastatin fọrọ nke nta ka ọ bụrụ nke na-egbochi protein ndị dị na plasma.

Ọ na-eme ka metabolism ya na imeju mepụta metabolites na-arụ ọrụ. Ọ na-ewe awa iri na anọ iji kpochapụ ya. Ihe ahụ na-ahapụ ahụ ahụ na bile. Mmetụta ya na-adịgide ruo awa 30.

Ihe ngosi na contraindications

A na-atụ aro Torvacard n'ọnọdụ ndị a:

• cholesterol di elu
• mụbara triglycerides
• hypercholesterolemia,
• ọrịa obi na ọrịa obi
• ihe gbasara nke ato na myocardial infarction.

Dọkịta nwere ike inye gị ọgwụ a n ’ọnọdụ ndị ọzọ, ọ bụrụ na ojiji ya ga - enyere aka melite ọdịmma onye ọrịa.

Mana maka nke a, ọ dị mkpa na onye ọrịa ahụ enweghị njirimara ndị a:

• nnukwu ọrịa imeju
• ụkọ lactase
• lactose na anagide glucose,
• erughị afọ 18
• anabataghị ihe mejupụtara ya
• ime
• nri eke.

Njirimara ndị a bụ ihe mgbochi, n'ihi nke a machibidoro iji Torvacard iwu.

Ọzọkwa, ntuziaka ahụ kwuru oge mgbe ịnwere ike iji ngwa a naanị na nlekọta nlekọta ahụike mgbe niile:

• alisụrụma
• ọbara mgbali ike
• Akwụkwụ na-adọ
• nsogbu metabolic
• ọrịa shuga mellitus
• sepsis
• nnukwu mmerụ ahụ ma ọ bụ nnukwu ịwa ahụ.

N'okpuru ọnọdụ ndị dị otú a, ọgwụ a nwere ike ibute mmeghachi omume na-enweghị atụ, yabụ achọrọ ịkpachara anya.

Ntụziaka maka ojiji

Naanị nchịkwa ọnụ ọgụgụ nke ọgwụ ahụ ka a na-eme. Dabere na nkwenye izugbe, na mbido mbụ ị ga-a drinkụ ọgwụ ahụ na ọnụọgụ 10 mg. A na-eme nyocha ndị ọzọ, dịka nsonaazụ nke nke dọkịta nwere ike ịbawanye dose ahụ ruo 20 mg.

Ọnụ ego kachasị maka Torvacard kwa ụbọchị bụ 80 mg. A na-ekpebi akụkụ kachasị dị irè maka ikpe ọ bụla.

Tupu ojiji, mbadamba adịghị mkpa ka a gwepịa ya. Onye ọrịa ọ bụla na-ewere ha n'oge kwesịrị ekwesị maka onwe ya, ọ naghị elekwasị anya na nri, ebe nri anaghị emetụta nsonaazụ ya.

Ogologo oge ọgwụgwọ nwere ike ịdị iche. Enwere ike ịchọpụta otu ihe ma emechaa izu abụọ, ma ọ nwere ike iwe ogologo oge iji gbakee.

Akụkọ vidiyo sitere na Dr. Malysheva banyere akpụ:

Ndị Ọrịa na Nduzi Pụrụ Iche

Maka ụfọdụ ndị ọrịa, akụrụngwa na-arụ ọrụ nke ọgwụ nwere ike ịme ihe ọ bụla.

Ojiji ya chọrọ ịkpachara anya banyere otu ndị a:

1. Womenmụ nwanyị dị ime. N'oge mmegharị ahụ, kọlestrọl na ihe ndị ahụ na - agwakọta site na ya dị mkpa. Ya mere, iji atorvastatin n’oge a dị ize ndụ nye nwatakịrị nwere nsogbu mmepe. N'ihi ya, ndị dọkịta anaghị akwado ọgwụgwọ maka ọgwụgwọ a.
2. Ndi nne na enye nri igbo. Ngwaọrụ a na-arụ ọrụ nke ọgwụ ahụ na-abanye na mmiri ara ara, nke nwere ike imetụta ahụike nke nwa. Yabụ, amachara iji Torvacard n'oge ị na-a breastụ ara.
3. Childrenmụaka na ndị nọ n'afọ iri na ụma. Ejighi otu esi eji Atorvastatin eme ha eme. Iji gbochie ihe egwu nwere ike ime, ewezuga ịhọpụta ọgwụ a.
4. Ndị nke agadi. Ọgwụ a metụtara ha yana ndị ọrịa ọ bụla ọzọ enweghị ọgwụ mgbochi ọ bụla. Nke a pụtara na maka ndị ọrịa merela agadi, ọ dịghị mkpa nhazigharị usoro onunu ogwu.

Enweghị ọgwụ ndị ọzọ maka ọgwụ a.

Suchkpụrụ nke usoro ọgwụgwọ ahụ na-emetụta ụdị ihe a dị ka ọnya ọnya isi. Ọ bụrụ na ị dị, mgbe ụfọdụ ị ga-achọ ịkpachara anya karị n'iji ọgwụ ọjọọ.

Maka Torvacard, ọrịa ndị dị ka:

1. Ọrịa imeju na-arụ ọrụ. Ọnụnọ ha so n'etiti ihe ndị ahụ na - eme ihe.
2. Mmụba ọrụ nke ọbara transaminases. Akụkụ ahụ nke a na-arụkwa ọrụ dị ka ihe kpatara na ịghara ị toụ ọgwụ ahụ.

Ọgba aghara na arụ ọrụ akụrụ, nke a na-etinyekarị na ndepụta nke contraindications, apụtaghị n'ebe ahụ n'oge a. Ọnụnọ ha anaghị emetụta mmetụta Atorvastatin, nke mere na a na-ahapụ ndị ọrịa dị otú ahụ ị takeụ ọgwụ ọbụlagodi na-enweghị nhazi usoro onunu ogwu.

Ọnọdụ dị oke mkpa bụ iji ọgwụ mgbochi ndị a pụrụ ịtụkwasị obi na-emeso ụmụ nwanyị na-amụ nwa afọ. N'oge nlekọta Torvacard, mmalite nke ịtụrụ ime anabataghị.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Mgbe ị na-eji Torvacard, nsonaazụ ndị a nwere ike ime:

• isi ọwụwa
• ehighi ura
• ọnọdụ obi mgbawa
• ọgbụgbọ
• nsogbu na-arụ ọrụ na ngụgụ nri,
• ọria aru
• nri riri
• akwara na mgbu
• ogwe
• nsogbu anaphylactic,
• itching
• akpụkpọ anụ ahụ,
• nsogbu mmekọahụ.

Ọ bụrụ na-achọpụta ihe ndị a na ndị ọzọ na-emebi, ị kwesịrị ịkpọtụrụ dọkịta gị ma kọwaa nsogbu ahụ. Mgbalị onwe onye wepụrụ ya nwere ike bute nsogbu.

Over overụbiga ọgwụ ókè kwesịrị ekwesị. Mgbe ọ mere, a na-egosi usoro ọgwụgwọ Symptomatic.

Mmekọrịta na ọgwụ ndị ọzọ

Iji zere mmeghachi ahụ anụ ahụ na-adịghị mma, ọ dị mkpa iburu n'uche peculiarities nke ihe ọgwụ ndị ọzọ ewepụtara na arụmọrụ nke Torvacard.

Ọ dị mkpa ịkpachara anya mgbe ị na-eji ya na:

• Erythromycin
• ya na ndị na-ahụ maka ọgwụ antimycotic
• fibrates
• Okirikiri
• nicotinic acid.

Ọgwụ ndị a na - enwe ike ịbawanye ụba nke atorvastatin n'ime ọbara, n'ihi nke enwere ọghọm nke nsonaazụ ndị ọzọ.

Ọ dịkwa mkpa iji nlezianya nyochaa ọganihu nke ọgwụgwọ ma ọ bụrụ na ọgwụ ndị dị ka agbakwunye Torvacard:

• Colestipol,
• Cimetidine
• Ketoconazole,
• ogwu gboro ya
• Digoxin.

Iji zụlite usoro ọgwụgwọ ziri ezi, dọkịta kwesịrị ịmara banyere ọgwụ niile onye ọrịa ahụ na-a .ụ. Nke a ga - enyere ya aka iji nlezianya nyochaa foto ahụ.

N'ime ọgwụ ndị dị mma iji dochie ọgwụ a na-atụle enwere ike ịkpọ:

Ekwesịrị ka ekwenye na ojiji ha na dọkịta. Ya mere, ọ bụrụ na ọ dị mkpa ịhọrọ analogues ọgwụ a adịghị ọnụ, ịkwesịrị ịkpọtụrụ ọkachamara.

Echiche onye ọrịa

Nyocha banyere ọgwụ Torvakard bụ ọgwụ megidere nke ukwuu - ọtụtụ wee pụta ọgwụ ahụ, mana a manyere ọtụtụ ndị ọrịa ịjụ ị takeụ ọgwụ ahụ n'ihi nsonaazụ ndị ọzọ, nke gosipụtara ọzọ mkpa ọ dị ka ịkpọtụrụ dọkịta na nyochaa ojiji.

Ejirila m Torvacard ọtụtụ afọ. Ihe ngosi nke cholesterol belatara site na ọkara, mmerụ ahụ emeghị. Dọkịta tụrụ aro ịnwale ọgwụgwọ ọzọ, ma ajụrụ m.

Enwere m ọtụtụ mmetụta ndị sitere na Torvacard. Isi ọwụwa, ọgbụgbọ, ihe na-akụ n'abalị. Ọ tara ahụhụ ruo izu abụọ, jụọ dọkịta ahụ ka o jiri ihe ọzọ dochie ọgwụ a.

Ọgwụ ndị a amasịghị m. Na mbu ihe nile dị n'usoro, mgbe ọnwa gasịkwara mgbali elu, oke ụra na isi ọwụwa pụtara. Dọkịta ahụ kwuru na ule ndị ahụ bịara dị mma, mana enwere m obi ọjọọ. Aghaghị m ịjụ.

Anọ m na-eji Torvard ọnwa isii ugbu a ma enwere m obi ụtọ dị ukwuu. Cholesterol dị mma, shuga agbadatala ntakịrị, nrụgide alaghachila nkịtị. Ahụghị m mmetụta ọ bụla.

Ọnụahịa Torvacard dịgasị iche dabere na usoro nke Atorvastatin. Maka mbadamba 30 nke 10 mg, ịkwesịrị ịkwụ ụgwọ 250-330 rubles. Buyzụta ngwungwu mbadamba 90 (20 mg) ga-achọ 950-1100 rubles. Mbadamba nwere ọdịnaya kachasị elu nke ihe na-arụ ọrụ (40 mg) na-efu 1270-1400 rubles. Ihe ngwugwu a nwere pcs 90.

Gini bu atherosclerosis ma obu ihe ojoo ya?

Atherosclerosis bụ ọrịa na - akpata ọbara n'ọbara site na izụpụta cholesterol plaques n'akụkụ nile nke akwara ndị ahụ, nke na-eduga na mmepe nke ọrịa ndị ahụ dị egwu nke na - egbu ndụ.

• Index ọbara mgbali elu,
• Ọrịa ụbụrụ nke akwara obi tachycardia, arrhythmia na angina pectoris,
• Myocardial infarction na ọrịa ụbụrụ,
• Ọbara ụdị ọbara ọgbụgba,
• Atherosclerosis nke aka n'ụkwụ na-eduga n'ịgba ndụ mbepụ.

Ihe ndị nwere nsogbu na-akpalite ịrị elu nke mkpokọta cholesterol n'ime ọbara na obere lipoproteins molecule nke LDL na VLDL.

Mgbu nke nta lipoproteins molecule dị ala yana nke elu ịdị elu nke moleculaine dị n'ọbara, obere ihe ọghọm nke imepụta atherosclerosis system.

Ihe onyunyo nke otu nke statins nke na-egbochi ihe HMG-CoA reductase, nke na - eme ka mevalonic acid mebie mkpụrụ ndụ akwara, na - enyere aka ịkpụkọta irighiri ihe nke lipoprotein, nke na - akpata ịba ụba nke lipoproteins dị ala.

Onye nnọchite anya Torvacard otu nke statins dị irè iji belata cholesterol dị njọ na ọrịa ndị dị ka:

• Ọrịa shuga mellitus
• Ya na obara obara,
• O nwere nnukwu nsogbu ibute ọrịa ọrịa obi.

Nrụ ọrụ na-arụ ọrụ na statin Torvacard bụ atorvastatin, nke na-agbada:

• Nchịkọta cholesterol n'ime ọbara dị 30.0% 46.0%,
• Theta mkpụrụ ndụ LDL na 40.0% 60.0%,
• Enwere mbelata na ntanye triglyceride.

Atherosclerosis

Ngwakọta nke ọgwụ ọgwụ nke statins Torvard

A na-emepụta Torvacard n'ụdị agba gburugburu na mbadamba ihe convex na shei nke nwere isi mejupụtara atorvastatin na usoro onunu ogwu nke 10.0 milligrams, 20.0 milligrams, 40.0 milligrams.

Na mgbakwunye na atorvastatin, mbadamba Torvacard gụnyere:

• Microcrystalline cellulose ụmụ irighiri ihe,
• Magnesium stearate na oxide ha,
• Mkpụrụ ndụ sodium molecule,
• Hypromellose na lactose,
• Sịlịkọn dioxide
• Titanium dioxide,
• Ihe oriri macrogol 6000.0,
• Talc.

A na-ere ọgwụ Torvacard na ọgwụ analogues ya na netwọ ọgwụ ahịa naanị site na ndenye ọgwụ nke dọkịta na-abịa.

Croscarmellose sodium

Releasedị mgbapụta Torvard

Mbadamba Torvacard statin dị na blisters nke 10.0 iberibe ma tinye ya na igbe kaadi 3, ma ọ bụ blisters 9. N'ime igbe nke ọ bụla, onye na-emepụta mbadamba ihe eji etinye ndụmọdụ maka ojiji, na-enweghị ọmụmụ nke ị na-enweghị ike ịmalite iburu Torvacard.

Ọnụahịa ọgwụ dị na netwọ ọgwụ ahịa na-adabere na usoro onoduvastatin bụ isi nke atorvastatin yana ọnụ ọgụgụ mbadamba dị na ngwugwu, yana mba mepụtara.

Russian analogues dị ọnụ ala karịa:

Na Russia, ị nwere ike ịzụta analogues nke Torvacard dị ọnụ ala site n'aka onye na-emepụta Russia, dịka ọmụmaatụ, ọgwụ Atorvastatin na ọnụ ahịa nke ruru 100,00 rubles Russia.

Ihe analog a bu ezigbo ego.

Mlọ ọgwụ

Torvacard bụ ọgwụ ọgwụ sinetọ nke statin otu, nke ebumnuche iji gbochie HMG-CoA reductase iji gbochie njikọta cholesterol zuru oke. Ọbara nwere cholesterol n'ime akụkụ niile.

Torvacard, n'ihi isi ihe mejupụtara atorvastatin, na-ebelata ntinye uche na ọbara:

• Ngụkọta cholesterol,
• Nnukwu irighiri irighiri ihe ụmụ irighiri ihe,
• Mkpụrụ ndụ dị ala dị ala lipoproteins,
• Mkpụrụ irighiri Triglyceride.

Omume nke statin Torvakard na-eme ọbụnadị mmepe nke ụdị mkpụrụ ndụ ihe nketa dị:

• Homozygous na heterozygous ketara eketa hypercholesterolemia,
• Isi akwukwo nke hypercholesterolemia,
• Usoro ngwakọta nke dyslipidemia.

Ọrịa ezinụlọ na-arịa ọrịa anaghị anabata ọgwụgwọ ọzọ.

Torvacard nwere akụrụngwa nke ime ihe na akwara mkpụrụ ndụ iji mee ka njikọ ahụ dị elu nke mkpụrụ ndụ belata nke ukwuu, nke belata ohere ị nwere ibute ọrịa ndị dị na akwara obi na n'ọbara.:

• Anụghị angina nwere ischemia nke akụkụ ahụ obi,
• Myocardial infarction
• Ischemic na hemorrhagic ụdị ọrịa strok,
• Thrombosis nke isi akwara,
• Sistem atherosclerosis.

Isbọchị ọgwụ nke Torvakard ka a na-ahọpụta site na dọkịta na-aga eleta na ndabere nke plọgum yana njiri mara nke ahụ onye ọrịa.

Isbọchị ị attendingụ ọgwụ Torvacard ka dọkịta na-ahụ maka ịga n'ihu họpụtara

Mlọ ọgwụ

Ngwakọta ọgwụ ọgwụ Torvacard nke statins adịghị adabere n'oge ịre mbadamba ya ma ejikọghị ya na nri:

• Usoro oriri nke aru site na ahu. Aborọsọ na - aputa ihe n’esite na - agbari nri ma mgbe ewere ọgwụ, pịnye ya n’ọbara n’ime elekere 1 2. Ihe a na-a absorụ n ’usoro ahụ na-adabere n’usoro nke ihe ndị na-arụ ọrụ n’ime ya na mbadamba Torvacard. Bioavailability nke ọgwụ ahụ dị 14.0%, ihe mgbochi na mbenlata mbelata ruru 30.0%. Ọ bụrụ na a na-eji ọgwụ ahụ na mgbede, mgbe ahụ belata nchịkọta cholesterol site na 30.0%, oge nchịkwa anaghị adabere na ngosipụta nke iwetulata irighiri ihe dị ala,
• Nkesa nke aru oru nke atorvastatin n’ahu. Ihe kariri 98.0% nke ihe mejupụtara atorvastatin na - egbochi nchekwa.Nnyocha nke ọgwụ ahụ gosipụtara na atorvastatin na-abanye na mmiri ara, nke machibidoro ị takingụ Torvacard mgbe nwanyị na-enye nwa ara,
• Ọgwụ metabolism. Metabolism na-apụta nke ọma na metabolites na-arụ ọrụ karịa 70.0% nke mmetụta inhibitory na mbelata,
• Wepu ahihia nke ihe di n’ime aru. Akụkụ buru ibu (ihe ruru 65.0%) nke arụ ọrụ na atorvastatin bụ ihe adị na mpụga bile acid. Ọkara ndụ nke ọgwụ ahụ maka awa 14. Na mmamịrị, ọnaghị achọpụta ihe karịrị 2.0% nke atorvastatin. Emere ọgwụ ndị ọzọ ọgwụ site na iji feces,
• Omume mmekọahụ na mmetụta nke Torvacard, yana afọ onye ọrịa. N'ime ndị ọrịa nke ụmụ nwoke meworo agadi, pasent nke iwetula ụmụ irighiri ihe LDL dị elu karịa na ụmụ nwoke. N'ime ọbara nke ahụ nwanyị, itinye uche nke ọgwụ Torvacard dị ukwuu karị, n'agbanyeghị na nke a enweghị mmetụta na nbelata ọnụọgụ nke LDL. E kenyere Torvacard n'aka ụmụaka na-erubeghị afọ ole ha dị,
• Pathology nke akụrụ. Ọdịda akụrụngwa, ma ọ bụ ọrịa akwara ndị ọzọ anaghị emetụta ịta nke atorvastatin n'ọbara onye ọrịa, yabụ, achọrọ idozi usoro usoro kwa ụbọchị. Atorvastatin na-ejikọ ọgwụ protein ike, nke na-adịghị emetụta usoro hemodialysis,
• Pathology nke mkpụrụ ndụ imeju. Ọ bụrụ na ọrịa metụtara ịba ọcha n'anya na-a alcoholụ mmanya, mgbe ahụ, ihe mejupụtara atorvastatin na-aba ụba nke ukwuu na ọbara.

Lọ ọgwụ ọgwụ Torvacard nke statins adịghị adabere na mgbe ị na-ewere mbadamba nkume ndị ahụ.

Mmekọrịta na ọgwụ ndị ọzọ

Ozi a gosipụtara na nha pasent bụ ọdịiche dị na data gbasara iji Torvacard iche. AUC - mpaghara dị n'okpuru usoro na-egosi ọkwa nke atorvastatin ruo oge ụfọdụ. C max - ọdịnaya kachasị elu nke ihe oriri n'ime ọbara.

Nchikota Torvacard na analorọ ya na ogwu ndi ahu nwere ike ibute oria akwara rhabdomyolysis.

• Ọgwụ cyclosporin,
• Ogwu ahụ dị styripentol,
• Ejikọtara statins na telithromycin na clarithromycin,
• Delavirdine na-enye ọgwụ,
• Ketocanazole na Voriconazole,
• Ọgwụ Posaconazole na Itraconazole,
• Ọrịa nje HIV na-egbochi ya.

Nchikota Torvacard na analorọ ya na ogwu ndia nwere ike ibute oria akwara gbasara akwara.

Ọgwụ Torvacard na nje ya

E nyere ọgwụ Torvacard na ọgwụ analogues ka mgbochi nke abụọ:

• N'oge nzaghachị infarction,
• Mgbe ọnya na-egbu mgbu na
• Mgbe mwepụ nke thrombosis na pathology nke thrombosis.

E dekwara Torvacard na analogues ya iji gbochie mmepe nke atherosclerosis na ọrịa obi, n'ime ndị ọrịa nwere ihe ndị dị ize ndụ a:

• Agadi
• Mmanya na-egbu egbu,
• Ise anwụrụ,
• Site na ọbara mgbali elu.

Denye ọgwụ Torvakard, ma ọ bụ ọrịa ya maka ọrịa ndị dị na ahụ mmadụ:

• Ndeputa nke apoliprotein B nke ukwu, yana otutu ihe cholesterol na ihe ndi di ala n’aru ya, ihe bara uba nke triglycerides n’ime mejuputara obara n’ihi ezin’ulo na nke ozo.
• Ederede dị elu nke triglyceride molecules nke ụdị 4 (nkewa Fredrickon), mgbe ọgwụ ndị ọzọ adịghị arụ ọrụ,
• Site na oria ogwu, pịnye 3 dysbetalipoproteinemia (nkewa Fredrickson),
• Site na ọrịa ogwu gbasara ọrịa obi yana oke ahụike nke akwara ischemia.

Contraindications Torvacard ma ọ bụ ndị analogues ya

Edebela ọgwụ Torvacard, yana analogues ya n'ọnọdụ ndị dị otú a:

• Nnukwu anụ ahụ maka ihe ndị dị na mbadamba nkume,
• Pathology nke akwara mkpụrụ ndụ na-amụba ọrụ nke ụmụ irighiri ihe transminase,
• Mkpesa mkpụrụ ndụ akwara nwatakịrị (ọkwa A ma ọ bụ B),
• Ọmụmụ ọrịa nke lactose anagidee,
• Womenmụ nwanyị dị ime afọ na-enweghị mgbochi afọ ojuju,
• Womenmụ nwanyị dị ime na nne na-enye nwa ara,
• Zụlite nwa gị ruo afọ 18.

Uzo eji statin Torvakard, ma obu ntule ya na usoro ubochi ya

Oge kachasị dị mma iji were mbadamba Torvacard, ma ọ bụ analogues, bụ tupu ụra, n'ihi na n'abalị, ịta cholesterol bụ ihe kachasị elu.

Usoro ị ofụ ọgwụ na Torvacard analogues na ọgwụ ahụ n'onwe ya kwesịrị ịnwe nri cholesterol.

Ssụ ọgwụ kwa ụbọchị na izi ezi nke nhazi ha:

• N'ime usoro ọgwụgwọ mbụ, usoro ọgwụ kwa ụbọchị nke 10.0 milligrams, ma ọ bụ milligram 20.0, ka a na-enye, dabere na lipogram,
• Ọ bụrụ n’ịchọrọ iwetulata mpempe akwụkwọ LDL site na 45.0% 50,0%, mgbe ahụ ị nwere ike ịmalite usoro iji usoro onunu ogwu nke 40.0 kwa ụbọchị. Iji wedata cholesterol ngwa ngwa, dọkịta ahụ n'onwe ya na-ekpebi ọgwụ ọ ga-eji Torvacard, ma ọ bụ Atorvastatin (analogue Russia),
• Oke kasịnụ a na-anabata ị doụ ọgwụ a na ọgwụ ya na ihe analogues ekwesịghị gafere 80.0 milligrams,
• Dochie ọgwụ ahụ na analog ya nwere ike ịme tupu ụbọchị iri atọ ebidochara usoro ọgwụgwọ. A na-edochi ọgwụ ma ọ bụrụ na ọgwụ egosipụtaghị mmetụta ọgwụgwọ dị mkpa, ma ọ bụ na-emetụta ahụ onye ọrịa ahụ n'ụzọ na-adịghị mma. Ọ dị mkpa ịga hụ dọkịta nwere nsonaazụ ya, ọ ga - achọpụta n'etiti ndị analogues na ọ ka mma ịnọchi Torvacard,
• Ejila Torvacard, ma obu ihe omuma ya dika ogwu nke onwe gi.
• Mgbe ị na-emeso ndị statins, mmadụ ekwesịghị ichefu na ọgwụ ndị otu a na mmanya na-ekwekọghị.

Amachibidoro iji Torvacard maka ụmụ nwanyị dị ime

More analogues

A na-ahụ ọgwụ, ebe akụkụ bụ isi bụ atorvastatin, bụ analogues nke Torvacard. Ọzọkwa, analogues nke ọgwụ a nwere ike ịbụ ọgwụ ọgwụ, nke akụrụngwa nọ n'ọrụ bụ rosuvastatin.

Ihe analogues ndị a metụtara ọgbọ ọhụrụ, ebe mmetụta ole na ole na-emetụta ahụ yana ezigbo ọgwụ.

Analogs nwere atorvastatin dị ike:

• Statin Atoris,
• Ihe atụ Russian nke Atorvastatin,
• Ọgwụ Atomax,
• Liprimar ọgwụ,
• Mbadamba ụrọ Liptonorm,
• Tulip ọgwụ.

Analogs nwere rosuvastatin nọ n'ọrụ:

• Rosuvastatin na Ọgwụ,
• Crestor ọgwụ,
• Mbadamba ụrọ Rosucard,
• Ọgwụ Roxer
• Ọgwụ Rosulip.

Ngwakọta, ụdị ntọhapụ

Atorvastatin - naanị otu ihe eji eme ihe na Torvacard. Achọrọ ihe ndị ọzọ fọdụrụnụ iji nye mbadamba mbadamba ụbara, mee ka ndụ ndụ ya dịwanye elu, melite mgbaze ọgwụ. Ndị pụrụ iche: magnesium oxide, cellulose, lactose monohydrate, ssumum croscarmellose, hyprolose, silicon dioxide, magnesium stearate, shei (hypromellose, macrogol, titanium dioxide, talc).

Torvacard bụ mbadamba ụrọ, oval, nwere ihe dị ka 10, 20, 40 mg nke ihe arụ ọrụ. A na-emepụta ngwugwu 30, 90 iberibe.

Omume ọgwụ

Torvacard bụ onye nnọchianya hypolipidem si na otu nke statins. Akụkụ ya na-arụ ọrụ, atorvastatin, nwere ikike igbochi ọrụ nke enzyme HMG-CoA. Enzyme ahụ na-ejide otu n'ime mmeghachi mmezi mmemme cholesterol. Na-enweghị ya, usoro nke ịmalite ikuku na-akwụsị. Ihe cholesterol ọbara na-amalite ijulata.

N'ịchọ ịkwụ ụgwọ maka ụkọ sterol, anụ ahụ mebiri "LDL" ọjọọ "nke nwere ya. N'otu aka ahụ, ọ na - eme ka lipoproteins dị elu nke “dị mma” (HDL) dị mkpa, iji wepụta cholesterol na imeju site na akwara anụ ahụ.

Iwere mbadamba Torvacard nwere ike belata cholesterol site na 30-46%, LDL - site na 41-61%, triglycerides site na 14-33%. Normalization nke profaịlụ lipid na-enyere aka belata mmepe nke atherosclerosis. Ekwenyere na cholesterol LDL dị elu, yana HDL dị ala, na-arụ ọrụ dị mkpa na mmepe ya.

Torvacard na-enyere aka belata LDL n’ime ndị ọrịa nwere familial homozygous hypercholesterolemia. Usoro a bụ nke dabere na dose: nke buru ibu na dose ahụ, yabụ itinye uche ha na-ebelata.

Atorvastatin na-abanye ahụ ngwa ngwa. N'ime awa 1-2 ka nchịkwa gasịrị, ọkwa ya n'ime ọbara ruru oke. Mgbe iwere Torvacard, ọ na-arụ ọrụ ruo awa 20-30 ọzọ.

Ọgwụ dị n’ire (98%), yana akụrụ (2%). Ya mere, enwere ike inye ya ndị ọrịa nwere nsogbu gbasara akụrụ. Mana enwere nsogbu imeju, a ga-eji nlezianya kpoo ya.

Na-agbada cholesterol, LDL ekwughi ozugbo. Ọ na-ewe izu abụọ iji rụpụta ihe bụ isi. Torvakard gosipụtara ike kachasị mgbe izu anọ gachara site na mmalite nke nchịkwa.

Torvacard: ngosipụta maka ojiji

Torvacard, dịka statin ọ bụla, ka enyere ya maka ndị na-enwebeghị ike ịme kọlọdi, LDL ka ọ bụrụ nri nri. Dịka ntuziaka ahụ si dị, egosi Torvacard maka:

• hereditary homo-, heterozygous hypercholesterolemia na cholesterol dị ala, LDL, apolipoprotein B, mụbaa HDL,
• triglyceridemia,
• dysbetalipoproteinemia.

N'ọnọdụ pụrụ iche, enyere ọgwụ maka Torvacard maka ụmụaka 10-17 dị afọ, n'ime onye, ​​mgbe usoro ọgwụgwọ nri gasịrị, kọlestrọl adabaghị n'okpuru 190 mg / dl ma ọ bụ LDL n'okpuru 160 mg / dl. Ihe ngosi nke abuo kwesiri ijikọ ya na ihe ketara eketa banyere mmepe nke oria obi ma obu inwe ihe ojoo ≥ 2 maka uto ha.

Atorvastatin ka edepụtara maka igbochi ọrịa nke akụrụngwa obi. Na ụdị asymptomatic ụdị ọrịa obi obi, ndị mmadụ nwere ọtụtụ ihe ọghọm maka mmepe ya (ị smokingụ sịga, ịhoụ mmanya, ọbara mgbali, HDL dị ala, nhọpụta), nhọpụta atorvastatin na-enyere aka:

• belata ohere ịmụpụta ọrịa strok, nkụchi obi,
• gbochie ọgụ angina,
• Zere ịwa ahụ iji weghachi ọbara nke nkịtị.

Ndị ọrịa nwere ọrịa shuga ndị nwere ihe ize ndụ nke ịmalite ọrịa obi, a na-enye ọgwụ ahụ ka ọ belata ohere nke ịmalite ọrịa obi, nkụchi obi.

Ndị ọrịa nwere ọrịa obi na-eburu Torvacard maka:

• belata ihe ize ndụ nke infarction myocardial, ọrịa strok (ya na / na-enweghị ọnwụ),
• na -ebelata ọnụ ọgụgụ ụlọ ọgwụ maka ọrịa obi ọria obi,
• mgbochi angina pectoris.

Ofzọ nke ngwa, usoro onunu ogwu

A na-ewere Torvacard otu ugboro / ụbọchị, tupu, emechaa, ma ọ bụ jiri nri. Ọ dị mkpa ịrapara n'otu oge nnabata. Erere mbadamba ihe nile (a chetala, enyekwala ya), jiri mmiri ọ .ụ washedụ sachaa ya.

Ọgwụ Torvacard na-amalite site na obere usoro onunu ogwu. Ka izu anọ gachara, dibia nyochaa ọkwa cholesterol, LDL. Ọ bụrụ na arụpụtaghị nsonaazụ achọrọ, a na-abawanye ọgwụ a. N’ọdị n’ihu, a na-eme mgbanwe mmegharị oge niile n’etiti oge dịkarịa ala izu anọ. Usoro kachasị maka Torvacard bụ 80 mg. Ọ bụrụ na atorvastatin dị otú ahụ enweghị ike inye kọlọlẹle nkịtị, a na-enye statin dị ike ma ọ bụ ọgwụ ndị ọzọ nwere mmetụta yiri ya.

Ngwọta mbụ akwadoro nke Torvacard maka ịgwọ ndị ọrịa nwere hypercholesterolemia, ọrịa dyslipidemia bụ 10-20 mg / ụbọchị. A na-enye ndị ọrịa chọrọ mgbada cholesterol ihe mberede (karịa 45%) ozugbo 40 mg.

Otu usoro ọgwụgwọ a na-esochi mgbe ị na-edepụta ndị ọrịa ọrịa oria akwara ozi atorvastatin. Ntuziaka maka Torvacard bụ ndụmọdụ nke European Society maka Atherosclerosis maka ebumnuche nke usoro ọgwụgwọ belata. Ekwenyere na akara maka ihe ịga nke ọma ga-abụ mmezu nke kọlestrọl ọnụ

Dabere na ntuziaka maka iji Torvacard, ekwesighi inye ndị ọrịa nwere ọgụgụ isi na atorvastatin ọgwụ, akụkụ ndị ọzọ nke ọgwụ ma ọ bụ statins. Ndị ọrịa nwere ụkọ lactose kwesịrị ị attentiona ntị na ọnụnọ nke lactose.

• na nnukwu ọrịa ịba ọcha n'anya,
• na-aga n'ihu na-abawanye na transaminases nke amabeghị sitere,
• umuaka (ma ewezuga umuaka heterozygous hypercholesterolemia)
• ime
• lactating
• womenmụ nwanyị nọ n'afọ ndụ ịmụ nwa na-adịghị eji ọgwụ mgbochi pụrụ ịdabere na ya.

Ọ bụrụ na nwanyị dị ime mgbe ọ na-ewere Torvacard, a na-akwụsị ọgwụ ahụ ozugbo. Cholesterol dị mkpa maka nwa ebu n'afọ tolite nke ọma. Nlele na oke gosiri na ụmụ anụmanụ na anata atorvastatin mụrụ ụmụ. Ihe omuma a dika ndi okacha amara zuru oke iji gbochie iji ihe nlere anya di na nwanyi di ime.

Ọtụtụ ndị ọrịa na-anabata ọgwụ ahụ nke ọma. Mmetụta dị n'akụkụ anaghị emetụta ogo ndụ, gafere n'ime ụbọchị ole na ole ma ọ bụ izu. Categoriesfọdụ ndị mmadụ na-anabata usoro ọgwụgwọ siri ike karị. Ndị ọrịa na-alụbeghị di na-eche nnukwu ọrịa ihu. Ihe nwere ike ime na Torvacard:

• rhinitis, akpịrị mgbu,
• mmeghachi omume nfụkasị ahụ
• nnukwu shuga
• isi ọwụwa
• imi
• mmebi nke digestive tract (afọ ntachi, gas, ọgbụgbọ, dyspepsia, afọ ọsịsa),
• nkwonkwo, olu mgbu,
• akwara mgbu
• mụbara ALT, AST, GGT.

• shuga dị ala
• uru dị ukwuu
• anorexia
• ehighi ura
• n’abali
• anya ntughari
• nsogbu uche
• nụrụ ụtọ njo
• amnesia
• ọhụhụ ụzọ
• tinnitus
• ike adighi ike
• olu mgbu
• ọzịza
• ike ọgwụgwụ
• ahụ ọkụ
• urticaria, itching, ihe otutu,
• leukocyturia,
• aba ụba haemoglobin glycosylated.

• thrombocytopenia
• neuropathy
• mmebi anya
• cholestasis
• Imeji Quincke,
• obi ilu,
• myopathy
• olu ara
• rhabdomyolysis,
• tenopathy
• imebi ire ere.

• anafilais,
• ntị chiri
• imeju imeju
• gynecomastia
• ọrịa ngụgụ.

Ejiri Torvacard dọọ ndị mmadụ aka na ntị ịmalite ịrịa ọrịa rhabdomyolysis. Tupu ịmalite ọgwụgwọ, yana oge niile, ha kwesịrị ịchịkwa ọkwa nke creatine kinase. Ndị ọrịa nwere:

• ọrụ ezughi oke,
• ụbụrụ thyroid (hypothyroidism),
• nsogbu sitere na akwara ọkpụkpụ (ya na ndị ikwu),
• myopathy / rhabdomyolysis mgbe ewerechara akụkọ statins,
• ọrịa imeju na / ma ọ bụ ahoụrụma.

Ekwesịrị ịkpachapụ anya n'otu usoro ahụ maka ndị agadi (karịa karịa 70), na-eburu n'uche ihe ndị ọzọ dị ize ndụ.

Ikwesiri ịkwụsị iji Torvacard nwa oge, gwa dọkịta gị ma ọ bụrụ na ị nwere:

• mgbachi na-enweghị nchịkwa
• ọkwa ọbara dị elu / nke dị ala,
• nsogbu ahụ dara nke ukwuu
• nnukwu oria
• n'ihe banyere ịwa ahụ ma ọ bụ mberede.

Mmechi

Ọgwụ nke Torvakard otu nke statins bụ ọgwụ dị mma na-alụ ọgụ megide cholesterol na-adịghị njọ ma dịkwa njọ, nke nwere oke analogues, nke na-enye ohere ịme usoro ọgwụ.

Mmetụta nke statins na-abawanye nri cholesterol. Ejila Torvacard na analogues maka ogwu nke onwe gi na ezinulo gi.

Veronika, afọ 35: Enwere m ọrịa hypercholesterolemia, a chọpụtara na o nwere nsogbu ezinụlọ. Ekwesịrị m iji ọgwụ dị ala belata cholesterol, mana dọkịta ahụ kwụsịrị na mbadamba Torvakard.

Anọwo m na-ewere ha maka ọnwa ndị ahụ, mana mmetụta mbụ m mere mgbe m theụ ọgwụ ndị ahụ mgbe ọnwa gasịrị. N’ọnwa ndị a, kọlestrọl anaghị ebili. Torvacard enweghị mmetụta ọjọọ n'ahụ m.

Svyatoslav, afọ 46: Achọpụtara m na atherosclerosis ozugbo m ruru afọ 40, na kemgbe ahụ, anọwo m na-eme usoro ọgwụgwọ ọrịa statin mgbe niile. Elekere, usoro ọgwụgwọ dịruru ọnwa iri na abụọ n’ime ọnwa iri na abụọ, mana ọ na-ebute ihe na-akarịghị ọnwa isii, mgbe ahụ cholesterol na-efe efe ọzọ.

Otu afọ na ọkara gara aga, dọkịta ahụ weere m ọgwụ Torvakard. Ejiri m ya ọnwa 5, ma enwere m mmetụta nke ọgwụ a mgbe otu ọnwa gachara. Kemgbe afọ ahụ, kọlestrọl m dị nkịtị, ugbu a ọ malitela ịrị elu, ma na-enweghị nnukwu mkpọda.