Ntụziaka maka iji Glidiab MV
Usoro ọgwụgwọ maka ọrịa shuga abụghị naanị mgbanwe nri, kamakwa iji ọgwụ pụrụ iche.
Ọrịa ụdị nke abụọ, ndị mmadụ na-edekarị ọgwụ iji nweta mgbatị nkịtị. Otu ọgwụgwọ dị otú ahụ bụ Glidiab MV.
Ozi izugbe, ihe mejupụtara na ụdị ntọhapụ
Ọgwụ Glidiab MV bụ otu sitere na usoro sulfonylurea (ọgbọ abụọ), yabụ ebum n'uche ya iji kpalite sel beta dị na pancreas.
A na-emepụta ọgwụ ahụ na mpaghara Moscow site na ụlọ ọrụ ọgwụ Akrikhin ma bụrụ nke a na-ewere dị ka ihe atụ nke hypoglycemic mbadamba Diabeton MV, nke arụpụtara na France. Lọ ọrụ ahụ nwere usoro onunu ogwu eji eme ka amata tọhapụ ya.
Ogwu a di n ’ud i mbad i nwere ihe oma. Ha yiri mpụta nke clinda ewepụghị. Ọgwụ ahụ dị na ngwugwu nke mbadamba 30 ma ọ bụ 60.
E jiri ya tụnyere Diabeton MV, nke nwere onodu ogwu nke 0.06 g, Glidiab MV nwere ọkara ihe eji arụ ọrụ (0.03 g).
- Gliclazide bụ ihe kachasị mkpa,
- cellulose (microcrystalline),
- hydroxypropyl methylcellulose,
- stereta magnesium,
- Aerosil
Edere ọtụtụ ndị ọrịa Glidiab 80, nke nwere ihe nọ n'ọrụ, ọ bụghị mgmịn 30, mana 80 mg na mbadamba ọ bụla.
Omume ọgwụ
Ngwa nke Glidiab MV na-emetụta ahụ dịka ndị a:
- mee ngwangwa insulin nke emepụtara na pancreas,
- mụbaa anụ ahụ uche na homonụ emepụtara,
- belata oge dị n’ime nri n’oge a na-ebuga insulin,
- n'okpuru mmetụta nke ọgwụ a, a na-eweghachi insulin insulin n'oge mmalite ma e jiri ya tụnyere ọgwụ ndị ọzọ na-eme ka sulfonylurea,
- melite usoro microcirculation n'ihi ntanye mkpụrụ ndụ platelet, mweghachi nke ngwangwa akwara na obere ihe ize ndụ nke microthrombosis,
- belata glycemia,
- nyere aka wepụ protenuria,
- jiri nwayọ nwayọ etolite,
- na-enyere aka ịbelata oke, dị n'okpuru nri nri.
Mlọ ọgwụ
Usoro ịmịkọrọ, nkesa n'ime ahụ, metabolism na excretion nke ihe mejupụtara ya bụ ndị a:
- Egwu. Ọgwụgwọ ahụ na-agbada kpamkpam site na nri digestive (eriri afọ). Ọbara ya na-abawanye na plasma nwayọ, wee rute nke kachasị site n'oge nchịkwa mgbe awa isii ma ọ bụ awa iri na abụọ gachara. Nri anaghị emetụta ọnụego nnabata. Ọgwụ dị irè maka 24 awa.
- Nkesa. Nkwado nkwukọrịta na protein ndị dị na plasma na ọgwụ ọgwụ dịka 95%.
- Metabolism. Usoro a na-aputa n'ime imeju, akwara site na nguzobe nke metabolites na-adịghị arụ ọrụ.
- Ojiji. Mgbapụta na-aputa site na akụrụ n'ụdị metabolites, naanị 1% nke ọgwụ na-apụta na mmamịrị. Kpochapu ọkara ndụ ọgwụ ahụ na-apụta na awa iri na isii.
Usoro ọgwụ ọgwụ nke ndị ọrịa nwere ndị agadi anaghị agbanwe agbanwe.
Ihe ngosi na contraindications
Mbadamba ụrọ Glidiab MV bụ ọgwụ hypoglycemic, yabụ, a na-eji ya na ọgwụgwọ nke ọrịa shuga 2, mgbe ụzọ ndị ọzọ nke iwetulata glucose ewetaghị ihe ngosi gosipụtara na nkịtị.
Ihe ndi choro igbochi ogwu a:
- ketoacidosis
- arụ ọrụ akụrụ
- Ọrịa shuga 1dị 1
- Coma (ọrịa shuga ma ọ bụ hyperosmolar),
- arụmọrụ
- mmerụ ahụ
- bowel mgbochi,
- ime
- ọnọdụ na-akpata hypoglycemia (dịka ọmụmaatụ, ọrịa nke efe efe),
- leukopenia
- oke oku
- hypersensitivity na bekee na mejupụtara ngwaahịa a,
- inye ara.
Ntuziaka maka iji ya na ndụmọdụ pụrụ iche
Usoro ị drugụ ọgwụ ahụ dabere na njirimara nke ọrịa shuga na ngosipụta ya, yabụ ndị dọkịta ahọpụtara ya n'otu n'otu maka onye ọrịa ọ bụla.
Na mbido ị theụ ọgwụ ahụ, a na-atụ aro ị aụ ọgwụ 30 mg ma ọ bụ mbadamba 1. Dabere n'ọnọdụ onye ọrịa n'oge ọgwụgwọ, enwere ike ịba ụba nke ihe na-arụ ọrụ kwa ụbọchị ruo 120 mg (oke kachasị).
A na-ewere mbadamba okwu ọnụ n'oge nri ụtụtụ (otu ugboro n'ụbọchị). Pairrụ ọrụ akụrụ dị nwayọ (na creatinine si na 15 ruo 80 ml / min) anaghị achọ idozi dose.
Na mbido ọgwụgwọ ọgwụ ma rue mgbe ahọrọ ọgwụ dị mkpa, ndị ọrịa na-enwekarị hypoglycemia ekwesịghị ịrụ ọrụ chọrọ nzaghachi ngwa ngwa ma ọ bụ nlebara anya dị ukwuu.
Womenmụ nwanyị ekwesịghị iji ọgwụ mee ihe n’oge oge ịmụ nwa, yana inye nwa ara.
Oru oke imebi akụrụ ma ọ bụ imeju machibidoro iji ọgwụ eme ihe ọbụla.
- Ihe achọrọ iji nweta nsonaazụ nke ngwa ahụ bụ isochi usoro nri na mmega ahụ na-agafeghị oke. N'ime nri ụbọchị, carbohydrates kwesịrị ịnọ na obere ego.
- Ọ dị oke mkpa na a na-enyocha glycemia tupu yana mgbe nri gasịrị ka enwere ike idozi ọnụọgụ dabere na nsonaazụ nha.
- Maka usoro ịwa ahụ ma ọ bụ oria na-arịa ọrịa diski, a ga-eji ọgwụ insulin dochie ọgwụ ahụ.
- Iji zere ịda ọrịa hypoglycemia, yana mmeghachi omume disulfiram, ị drinkụ mmanya.
- A machibidoro ya iwu iri nri, leghara nri ndị dị na nri n'oge mmalite nke agụụ.
- Tupu ịrụ ọrụ ike, a ga-ebelata dose ahụ.
Ihe kachasị emetụta ọgwụ hypoglycemic bụ:
- ndị mmadụ n’oge agadi
- ndị ọrịa na-enweghị ike iri ezigbo nri,
- ndị mmadụ nwere ahụ esighi ike
- ndị ọrịa nwere ọrịa ọrịa ụbụrụ pituitary-adrenal insufficiency.
Mmetụta akụkụ na ị andụbiga mmanya ókè
Illsnweta ọgwụ nwere ike ibute mmeghachi omume ndị a na mmadụ:
- n'ihe metụtara usoro endocrine - hypoglycemia nke nwere njiri mara isi ọwụwa, ọsụsọ, adịghị ike, ịda mba, ụdọ, ịma jijiji, enweghị mmụọ, ọhụhụ ụzọ na nhazi nke mmegharị,
- Site na nri diges - dyspepsia, anorexia, ọgba aghara na imeju,
- leukopenia, thrombocytopenia, anaemia,
- Ngosiputa nfụkasị (itching, ihe ngbu, ma ọ bụ urticaria).
Site na ịdoụbiga ọgwụ ókè, hypoglycemia na-apụta. Iji wepu ihe mgbaàmà ya, o zuru ezu iri ọtụtụ carbohydrates, ma ọ bụrụhaala na onye ahụ maara ihe. N'ọnọdụ ebe onye ọrịa enweghị ike ị takeụ nri n'onwe ya, ekwesịrị inye ya ọgwụgwọ glucose ọbara (40%) yana ntụtụ glucagon. Mgbe ị laghachitere onye na-arịa ọrịa shuga, ị ka ga -eme ihe ọ bụla iji zere ịda glucose ugboro ugboro.
Mmekọrịta na ọgwụ ndị ọzọ na analogues
Ojiji nke ọgwụ ndị ọzọ na njikọta na Glidiab MV nwere ike ịkwalite ma ọ bụ ibelata mmetụta hypoglycemic.
Ejikọtara ọgwụ na ọgwụ dịka:
- Ihe mgbochi ACE,
- antifungal elekọta mmadụ (fluconazole),
- Ndị NSAID
- ọgwụ mgbochi
- Fibrates
- ọgwụ mgbochi ụkwara nta
- Salicylates,
- Pentoxifylline
- Ethanol
- ọgwụ nke na - egbochi tubular secretion.
A na-ebelata hypoglycemic mmetụta mgbe ejikọtara ya na ọgwụ ndị a:
- mgbochi ego
- thiazide diuretics,
- Furosemide
- homonụ iji nọgide na-arụ ọrụ thyroid,
- nkwadebe lithium
- estrogens
- ụzọ nke mgbochi afọ ime.
N'ime ọgwụ ndị nwere otu mmetụta dị ka mbadamba Glidiab MV, ihe ndị a ka edepụtara bụ:
- Meglimide
- Ọlta
- Glibetic,
- Clay,
- Glimepiride
- Eglim
- Igwe
- Glibenclamide,
- Glurenorm.
Ihe omuma vidiyo banyere oria shuga, udiri ya na mgbochi ya:
Echiche nke ndị ọrịa na ndị dọkịta
Site na nyocha ndị ọrịa, anyị nwere ike ikwubi na a nabatara ọgwụ ahụ nke ọma yana arụmọrụ ya. Agbanyeghị, ndị dọkịta siri ọnwụ na ị usingụ ọgwụ ahụ naanị mgbe ọ kpọchara ọkachamara.
Ezigbo usọbọ. N’ihu nhụsianya siri ike, enwetara m ihe dị ka kilogram 30, n’agbanyeghi na agbanweghị m ụdị nri m na -eri. N'ihi ya, achọtara m shuga dị elu. Dọkịta nyere m iwu ka m were mbadamba 2 nke Glidiab MV kwa ụtụtụ, na ị toụ mbadamba 1 nke Glucofage 1000 na mgbede.Ekele usoro ọgwụgwọ a, ntanye glucose daa site na nkeji 4 wee nọgide na-anọ na gburugburu 7 mmol / L mgbe niile.
Kristina, onye ndidi, afọ 47
Ọgwụ dị mfe iji. Glidiab CF nwere ọtụtụ contraindications, yabụ ndị ọrịa ekwesịghị ịmalite iwere ya n'onwe ha na-enweghị nkwado mbụ site n'aka dọkịta na-abịa. Ọ dị mkpa iji nyochaa glycemia mgbe niile ma nyochaa ịdị irè nke ọgwụgwọ ọrịa shuga tinyere endocrinologist. Site na usoro ọgwụgwọ ahọpụtara n'ụzọ ziri ezi, ọ ga-ekwe omume ịhazi ogo glucose ngwa ngwa. A na-enye ọgwụ ahụ n pharm ụlọ ọgwụ ebe ọgwụ nyere ya ọgwụ, mana ụmụ amaala na-arịa ọrịa a na-enweta ya n'efu, n'okpuru ndị ọkachamara n'ụlọ ọgwụ ha na-ahụ maka ya mgbe niile.
Victor Vladimirovich, dọkịta
Ọnụahịa nke mbadamba 60 nke Glidiab MV na ngwugwu bụ ihe dịka 200 rubles.