Bagomet - ọgwụ na-ebelata shuga ọbara

Dabere na ntuziaka Bagomet bụ ọgwụ hypoglycemic sitere na ìgwè biguanide. Ọgwụ Bagomet na-egbochi gluconeogenesis na imeju, na-enyere aka belata nnabata glucose site na eriri afọ. Ọgwụ a na - akwalite ojiji nke glucose na - emegharị ahụ, na - eme ka mkpụrụ ndụ nke insulin dịkwuo nkọ. Nyocha banyere Bagomet na-egosi na ọgwụ a na-eme ka ọ dị mma, na -ebelata oke ahụ.

Bagomet egosi

Dabere na ntuziaka Bagomet, ndị dọkịta depụtara ndị ọrịa nwere ụdị ọrịa shuga 2 nke na-enweghị ketoacidosis. A na-ewere Bagomet ma ọ bụrụ na achọpụtala ọgwụgwọ nri na ọgwụgwọ na sulfonylureas adịghị mma na ọgwụgwọ. A na-ewere ọgwụ Bagomet na monotherapy ma ọ bụ na njikọta insulin ma ọ bụ ndị nnọchianya hypoglycemic.

Usoro onunu ogwu na nhazi

Dabere na ntuziaka Bagomet were ọnụ. Ekwesiri iburu n’uche na dọkịta kwesịrị ị theụ ọgwụ ọgwụ ahụ n’otu n’otu, dabere na ntinye glucose n’ọbara onye ọrịa. Enwere ike ibute Bagomet tupu nri ma mgbe nri gasịrị.

Ọ bụrụ na ndị ọrịa anaghị a insụ ọgwụ insulin, mbadamba Bagomet nwere ike ị drunkụ mmanya ugboro abụọ n'ụbọchị maka 1 gram. Ọ dịkwa mkpa iji ọgwụ ahụ na ụbọchị atọ mbụ nke ọgwụgwọ. You nwere ike drinkụọ dị ka atụmatụ ọzọ si dị - otu mbadamba nke Bagomet 500 mg ugboro atọ n'ụbọchị. Site n'ụbọchị nke anọ, atụmatụ ahụ gbanwere, ịkwesịrị ị were mbadamba abụọ nke Bagomet ugboro atọ n'ụbọchị. Yabụ ruo ụbọchị nke iri na anọ, gụnyere ya. Mgbe nke a gasịrị, a na-anwale ọbara na mmamịrị maka glucose. Site na ụbọchị nke iri na ise, ị ofụ ọgwụ Bagomet na-edozi. Dosebọchị kwa ụbọchị kwesịrị 1-2 g.

Ọ bụrụ na onye ọrịa ahụ nwere mbadamba 8,0 mg Bagomet, a ga-ewere ya ugboro abụọ n'ụbọchị, otu oge. Shouldkwesịrị ịmara na a ga-ewere gram atọ nke Bagomet na ọtụtụ ụbọchị.

Site na nhazi oge a nke Bagomet na insulin, onye ọrịa ga-ebelata ọgwụ insulin. Kwadoro ezi ndaba maka nnabata ụdị nnabata a kwesịrị inye dọkịta.

Bagomet mmetụta

Nyocha banyere Bagomet na-ekwu na ọgwụ nwere ike ibute nsonaazụ dị iche iche. Onye ọrịa ahụ nwere ike ịnweta ọgbụgbọ na ọgbụgbọ, ọnya afọ mgbe ị na-eji ọgwụ. Mgbe ụfọdụ iji Bagomet na-eme ka ụtọ nke ọla dị n’ọnụ. Ọgwụ ahụ nwekwara ike inye mmetụta ndị ọzọ: anaemia, nsogbu na -ebi agụụ, hypoglycemia. Iji Bagomet eme ihe ogologo oge na-ebute oke vitamin B12 n’ahụ mmadụ.

Ihe ngbanwe

Dabere na ntuziaka Bagomet enweghị ike iburu ya na hyperensitivity to metformin. A na-egbochi ọgwụ a na ọdịda akụrụ, ụkwara ume ọkụ, precoma, ketoacidosis. A naghị ewere Bagomet maka iku ume na nkụchi obi, nnukwu nkụchi obi, nnukwu ihe ọghọm cerebrovascular. Bagomet na-emegide contraindically na-egbu egbu ahoụrụma. Ọzọkwa, ndị dọkịta anaghị atụ aro ị thisụ ọgwụ a mgbe mmerụ ahụ na nnukwu arụmọrụ. Nyocha nke Bagomet na-ekwu na ọ naghị atụ aro ị takeụ ọgwụ maka ndị ọrịa mgbe afọ iri isii gasịrị.

Atụmatụ ọgwụ nke Bagomet

Bagomet bụ ọgwụ hypoglycemic na-ebelata ma shuga na-ebu ọnụ ma na-arụ ọrụ mgbe ọ risịrị. Ọgwụ anaghị emetụta njikọ nke insulin. Otu n'ime nsogbu ndị metụtara ọrịa hypoglycemia abụghị nke ekwesighi. Ọgwụgwọ enwere ike apụta mgbe mgbochi nke glycogenolysis na gluconeogenesis, nke na-akpalite mgbochi nke glycogen na imeju Ọgwụ na - enyere mkpụrụ ndụ aka ijide na ịhapụ glucose, na - eme ka amata ndị na - anabata ya na homonụ, ma na - egbochi nnabata nke carbohydrates site na mgbidi nke eriri afọ.

Bagomet na - akwalite arụmọrụ nke enzyme nke na - eme ka njikọ glycogen dịkwuo elu, na - eme ka ikike nke ụgbọ elu nke glucose dịkwuo elu. Ọgwụ ahụ na - eme ka metabolism dị ọcha - nke nwere ụdị ọrịa shuga 2 enwere ohere ida.

Bagomet jiri ya na ndị otu ya na-atụnyere nke ọma n'ihe banyere oke ngwa ngwa.

Mgbe etinyere nri, a na-enweta ọgwụ ahụ ngwa ngwa site na nri diges, a na-abanyekarị uche kachasị n'ime awa abụọ na ọkara. Na-akụda ohere nke ọgwụ yiri nri. Ihe ngosi bioavailability nke Bagomet bu ihe ruru 60% nke ngụkọta nke ọgwụ a enyere ndị akụkụ.

Dabere na nsonaazụ nke ọmụmụ ọgwụ, anyị nwere ike ikwubi na ọgwụ na-agafe ngwa ngwa site na anụ ahụ, na-achọpụta n'ime plasma. Ihe ndị mejupụtara ọgwụ ahụ ejikọtara na protein, ọ nwere ike banye na sel ọbara ọbara, mana n'ọbara, ha dị obere ma e jiri ya tụnyere plasma.

Nchọpụta egosipụtara na ọgwụ anaghị metabolized n'ime ahụ - akụrụ na-egosipụta ya na steeti mbụ ya. N'okwu a, ọkara ndụ ahụ bụ awa isii na ọkara. Bagometular filtration na renal tubule excretion na-akpasu iwe ọpụpụ, yabụ, ndị ọrịa niile nwere ọrịa gbasara akụrụ nọ n'ihe ize ndụ.

Ọkara ndụ na-abawanye, nke pụtara na enwere ihe ọghọm nke ịnakọta ọgwụ.

Ihe ngosiputa na uzo eji eji ya

A na-eme Bagomet maka ịgwọ ndị ọrịa mamịrị nwere ụdị ọrịa na-enweghị insulin na-enwere onwe ya (na enweghị ketoacidosis na nzaghachi na-ezughị ezu na ọgwụgwọ na sulfonylureas).

Ojiji nke Bagomet ga-ekwe omume naanị dị ka nkwenye nke endocrinologist, onye ga-akọwa usoro ọgwụgwọ na-eburu ogo ọrịa ahụ na ahụike nke onye ọrịa.

Ezubere ọgwụ ahụ maka ojiji nke ime. Jiri mmiri kwoo mbadamba nkume ahu. Nke a na - abụkarị nri ma ọ bụ ozugbo ọ gachara. Usoro ọgwụgwọ oge mbụ bụ 500-100 mg / ụbọchị, dabere na ọkwa nke glycemia. Nwere ike ịhazigharị usoro ọnụọgụ ọgwụ naanị ka izu abụọ nke nnabata ya na ileba anya nke ndị na-egosi glycemic.

Ọ bụrụ na dọkịta emebeghị mkpebi onwe onye banyere onye ọrịa, mgbe ahụ, a na-enye usoro ọgwụgwọ ọgwụgwọ ahụ ka ọ dị site na 1500 ruo 2000 mg. Ọ gaghị ekwe omume ịgafe ụkpụrụ kachasị. Ọ bụrụ na ọgwụ na-akpalite ọgba aghara nke stool, ị nwere ike imebi usoro kwa ụbọchị site na ugboro 2-3.

Site na usoro ogwu di mgbagwoju anya "Bagomet gbakwunyere insulin kwadebere", onunu ogwu dika 1500 mg / ubochi. Maka mbadamba nkume nwere ikike ogologo oge, oke kachasị mma kwa ụbọchị bụ 850 mg -1000 mg. Site na iji nnabata nkịtị, ha na-akwụsị na usoro mmezi nke 1700 mg / ụbọchị., Ọgwụ - 2550 mg / ụbọchị. Site na iji usoro ọgwụgwọ siri ike yana ọgwụ ndị ọzọ na-ebutelata shuga, a na-enye otu mbadamba (850 mg ma ọ bụ 100 mg).

N'oge ịbụ okenye, Bagomet anaghị ewe ihe karịrị 1000 mg / ụbọchị. Nwere ike ịkọ ọgwụ maka ụmụaka gafere afọ 10. Childrenmụaka, yana ndị okenye, kwesiri ịmalite usoro ọgwụgwọ site na 500-850 mg / ụbọchị. N ’oge nwata, ọgwụ kachasị kwa ụbọchị bụ 2000 mg.

Nsonaazụ

N'izugbe, ọtụtụ ndị ọrịa nabatara ọgwụ ahụ nke ọma, mana, dịka ọgwụ ọ bụla, enwere ike inwe mmetụta ndị ọzọ.

Nchoputa preclinical gosiri na Bagomet anaghị akpasu mutagenicity, carcinogenicity na teratogenicity. A gosipụtara mmetụta na-anọpụ iche na ọrụ omumu.

Nsonaazụ Njikọ Ọgwụ

Ike nke hypoglycemic nke Bagomet na-eme ka sulfonamides, insulin, acarbose, ọgwụ mgbochi steroidal na-abụghị ọgwụ mgbochi, ACE na MAO inhibitors, oxytetracycline, β-blockers.

Glucocorticosteroids, GOK, epinephrine, glucagon, ọgwụ hormonal thyroid, sympathomimetics, thiazide na "loop" diuretics, usoro nke phenothiazine na nicotinic acid gbochiri ọrụ ya.

A na - egbochi cimetidine na - ewepu Bagomet n’arụ ahụ. Ihe ikike anumanu nke anakpo Coumarin na egbochi mgbochi Bagomet.

Of useụ mmanya na-egbu oge na-akpalite lactic acidosis. Ngosipụta ya bu oke nke aru, myalgia, erughi ala na odiba, nsogbu nke dyspeptik, dyspnea, stool dissel, ita mba. Na mbido mbụ, onye ahụ metụtara ụlọ ọgwụ, achọpụtakwa nchọpụta ya site na inyocha nsonaazụ nke lactate n'ahụ yana anụ ahụ. .Zọ kachasị dị mma iji sachapụ ahụ nke toxins bụ ịba ọcha n'anya. Dabere na njiri mara, a na-emeju ya site na usoro ọgwụgwọ Symptomatic.

Doụbiga ihe mgbaàmà ókè

Ọ bụrụ na usoro onunu ogwu nke Bagomet karịrị akachasị anabata iwu, lactic acidosis nwere nsonaazụ kacha njọ n'ụdị coma na ọbụna ọnwụ ga-ekwe omume. Ọ bụ mmetụta ahụ ka ọ na-akpata site na ịba ụba nke ọgwụ n'ime ahụ yana nsogbu na mpụta ya site na akụrụ. Nsogbu na-ebilite n'ime awa ole na ole ma jikọta mgbaàmà njirimara:

• Ọrịa Dyspeptik
• Hypothermia,
• Mmebi nke n'afọ iri na ụma,
• Mgbu na afọ
• Myalgia
• Ọnwụ nke nhazi
• Ainta nkụ na ọrịa shuga.

Ọ bụrụ na opekata mpe akụkụ nke akara ndị edepụtara egosipụtara, a ga-akagbu Bagomet ngwa ngwa, onye ahụ kwesịrị ịgaghachi ụlọ ọgwụ.

Mwepụta wepụtara, ihe mejupụtara, ọnọdụ nchekwa

Mbadamba ụrọ nwere ike inwe ụdị dị iche iche na agba dị iche iche, dabere na usoro onyonyo: ọcha, gburugburu na convex - 500 mg nke ọ bụla, n'ụdị capsules 850 mg bluish na agba na 1000 mg na ọcha. Nke ikpeazụ a nwere ogologo ọrụ. Otu njiri mara ụdị mwepụta ahụ bụ akara nkewa yana akara ndị nrụpụta, nke dị n’elu mbadamba nkume niile.

Otu mbadamba ihe sitere na 500 ruo 100 mg nke metformin hydrochloride nke na-arụ ọrụ na mgbakwunye ndị nwere ụdị n'ụdị sodium croscarmellose, povidone, stearic acid, stachi ọka, lactose monohydrate.

Ekwesịrị itinye ihe enyemaka na ntinye ọgwụ ka ebe ụmụaka na-agaghị anabata ya, yana oke ruru 25 Celsius. Debe Bagomet ihe kariri afọ abụọ.

Mmechi na analogues nke ogwu

Ihe anakpo Bagomet gunyere ogwu nke ma ndi otu a (ogwu antidiabetic) na ihe ndi ahu na aru aru (metformin).

Anaakpọ Bagomet bụ ọgwụ nke enwere ọ dịkarịa ala otu ọrịa ma ọ bụ ọnọdụ dabara na akaebe a, ụdị shuga 2 dị.

1. Avandia
2. Apidra
3. Baeta
4. Glemaz
5. Glidiab
6. Glucobay,
7. Glurenorm,
8. Lymphomyozot,
9. Levemir Penfill,
10. Levemir Flekspen,
11. Multisorb,
12. Methamine
13. NovoFormin,
14. Pioglar
15. Mpempe akwụkwọ,
16. Mpempe.

Site na ọgwụgwọ siri ike na ọgwụ ndị ọzọ nwere mmetụta yiri nke ahụ, ọ dị mkpa ịtụle ohere nke hypoglycemia. Ọgwụ ahụ nwere ike imebi nhazi ma jiri nwayọ kwuo mmeghachi omume psychomotor, yabụ mgbe ị na - arụ ọrụ n’ezie ma ọ bụ mgbe ị na - akwọ ụgbọala, ọ ka mma ịkwụsị ị takingụ ọgwụ. Ojiji nke Bagomet gụnyere nnabata nke mmanye nri nwere obere carb nke na-a theụ oriri nke carbohydrates n’ime ọbara.

Nyocha banyere Bagomet

Banyere ọgwụ Bagomet, nyocha ndị dọkịta kacha dị mma. Dị ka ndị ọkachamara si kwuo, ị suchụ ụdị ọgwụ a ma ama na-eme ka nchịkwa glycemic nke glucose ọbara dị ka awa 12. Ohere dị otú a na-ekwe ya nkwa ụfọdụ: ị nwere ike belata ugboro ole ị na-a theụ ọgwụ, melite ileba anya nke usoro metabolic. N'otu oge ahụ, a na - eme ka nnabata nke ihe na - arụ ọrụ site na eriri afọ ma belata ihe ize ndụ nke ibute mmetụta ọjọọ.

Ndị ọrịa na-ahụkwa na ọgwụ dị: na Bagomet ọnụahịa (nchịkọta 850 mg) bụ naanị 180-230 rubles maka mbadamba 60. Wepụ ọgwụ ahụ na ọgwụ ahịa ka eji ọgwụ depụta ya.

Nkọwa nke ọgwụ ahụ enweghị ike ịbụ nduzi maka ojiji. Tupu ịzụta, ịkwesịrị ịgakwuru ọgwụ endocrinologist, tupu ịlogistụ ọgwụ Bagomet, gụọ ntuziaka maka ojiji sitere na onye nrụpụta. Enyere ozi banyere Bagomet maka mmekorita mmadu n'ozuzu ya na ikike ya abughi ntuziaka maka ọgwụgwọ onwe. Usoro ọgwụgwọ a ka ga --eche maka ogo ọria mamịrị, ọrịa na - efe efe na ọnọdụ ahụike nke onye ọrịa mamịrị nwere ike imepe ya.