Ojiji nke ọgwụ Blotran, uru na ọghọm ya

Blockdị nke usoro Blocktran bụ mbadamba 12.5 mg (nke a na-etinye ihe nkiri) na 50 mg (ihe mkpuchi 10) (pcs 10. N'ime blisters, na ngwugwu kaadiboodu 1, 2, 3, 5, ma ọ bụ 6 ngwugwu).

Nri arụ ọrụ: losartan potassium, na mbadamba 1 - 12.5 ma ọ bụ 50 mg.

Ngwa ntinye aka: sodium carboxymethyl stachi (sodium sitashi glycolate), celclose microcrystalline, lactose monohydrate, silloon silicon dioxide (aerosil), povidone (polyvinylpyrrolidone, povidone K17), stachi nduku, stek magnesium.

Ihe mejupụtara shell: titanium dioxide (E171), copovidone, polysorbate 80 (tween 80), talc, hypromellose (hydroxypropyl methylcellulose).

Mpempe mwepụta

• Mbadamba ụrọ biconvex pink-orange. Mbadamba 10 dị na ngwungwu ngwugwu, 1, 3, 2, 5 ma ọ bụ 6 na igbe kaadi.
• Mbadamba pink nke biconvex nke ụdị gbaa gburugburu, na ezumike - agba ọcha. Mbadamba 10 dị na ngwungwu ngwugwu, 1, 3, 2, 5 ma ọ bụ 6 na igbe kaadi.

Pharmacodynamics nke losartan

Angiotensin nke ụdị nke abụọ bụ vasoconstrictor siri ike, onye mgbasa ozi bụ isi sistemụ renin-angiotensin na njikọta isi pathophysiological ọbara mgbali ike. Losartan Ihe mgbochi Receptor angiotensinỤdị 2. Angiotensin ahọrọ nke ọma Pdị ndị mgba ọkụ AT1dị na gland adrenal, na akwara nke arịa ọbara, akụrụ na obi ma na - akpali vasoconstriction na mmepụta aldosteronena - enwekwa ike ịkpalite uto nke akwara mkpụrụ ndụ. Ihe a na arụ ọrụ ya metabolite igbochi mmetụta niile angiotensin 2dị abụọ na agbanyeghị isi ma ọ bụ usoro njikọta.

Losartan anaghị egbochi ndị ọzọ nabata ya homonụ ma ọ bụ ion ọwa na-edozi sistemụ akwara. Anaghị egbochi ya angiotensin na - agbanwe enzymena-ahụ maka inactivation bradykininna-ebute nsonaazụ ndị metụtara bradykinin na-eruta na adịkarịghị. Mgbe ị na-eji losartan enwere mmụba na ọrụ plasma renin, nke nke a na - akpali mmụba nke ọdịnaya nke ụdị 2 angiotensin na ọbara. Antihypertensive ọrụ na mbelata ịta aldosteroneọbara na-ejigide, nke na-egosi mmachi dị irè ndị na-anabata angiotensin.

Losartan na metabolite ya bụ isi nwere tropism maka ndị na-anabata ya angiotensin Typedị 1 bukarịrị ndị na-anabata ya angiotensin Ụdị 2. Metabolite ahụ akọwapụtara na-arụ ọrụ karịa losartan 10-40 ikp. Mgbe onye nchịkwa gachara, ihe a na-ebute ike ya kacha mma mgbe elekere isii gachara, wee were nwayọ belata oge awa 24 gachara. A na - edekọ mmetụta kachasị mma maka antihypertensive mgbe izu isii isii site na mmalite nke ọgwụ ọgwụ. Mmetụta a na-abawanye site na ịba ụba usoro onunu ogwu. losartan.

Losartan anaghị emetụta mgbanwe nke ahịhịa anaghị agbanwe agbanwe ịta ahụhụ norepinephrine n'ọbara ogologo oge.
Na ndị ọrịa nwere abawanye ventricle aka ekpe na ọbara mgbali ikelosartan, gụnyere na yana hydrochlorothiazide, na-ebelata ohere nke ọrịa obi na ọrịa.

Pharmacodynamics nke hydrochlorothiazide

Usoro nke ime ihe uredị ụdị thiazide amaghi. Ha anaghị emetụta nrụgide nkịtị.

Hydrochlorothiazide bụ abụọ ọgwụ antihypertensive, na diuretic. Ọ na - emetụta nlọghachi azụ nke electrolytes na tubules nke akụrụ. Odika otu ihe mgbakwunye ion dị elu chlorine na sodium. Natriurez esighi ike ọnwụ bicarbonateion potassium na igbu oge kalshial. A na-edekọ mmetụta diuretic ahụ awa 2 mgbe nchịkwa gasịrị, ruru oke mgbe awa 4 gachara wee rue awa 7-12.

Onye ka ekenyero

N'ime ntuziaka ahụ, ngosipụta maka ojiji nke Blocktran bụ naanị ihe abụọ:

1. Site n'ọbara mgbali elu, nhọpụta nke ọgwụ na-enye gị ohere ịnweta nrụgide na-akwụsị ike. Blocktran maka ngosipụta a ga-a dailyụ mmanya kwa ụbọchị ruo ogologo oge.
2. N’ewepu obi, a na-enye ọgwụ ọgwụ ka-elu dị ka onye dochie anya ndị na - egbochi ACE (mbadamba ọgwụ mgbochi na-ejedebe - adj) ma ọ bụrụ na ha na-akpata nsonaazụ.

Ntụnyere nke ịdị irè nke Blocktran na analorọ ya na ọgwụ ọbara mgbali elu nke ndị otu ọgwụ ọgwụ na-egosi na ọgwụ ndị a dị nso: ha na-enye nbilata otu nrụgide ahụ, echekwara nha anya pụọ ​​n'ọgba aghara mgbali elu na nsonaazụ ha dị egwu.

Blocktran na ọgwụ ndị ọzọ na losartan nwere ọtụtụ ọdịiche dị iche na ọgwụ mgbochi ọgwụ ndị ọzọ. Ọ bụ ọdịiche ndị a na-ekpebi oke ha nwere iji.

Ihe na - enyere aka Blocktran:

• Mbadamba ụrọ nwere mmetụta ngwụcha. Maka mmepe nke ime ihe kachasị, achọrọ nri kwa ụbọchị maka izu 2-5.
• mbelata nrụgide nke enwetara na Blocktran na-adịgide. Usedmata ọgwụ ahụ na iwelata ịdị irè ya na ọgwụgwọ ogologo oge na-apụta n'ọtụtụ oge na-erughị na ndị na-egbochi beta ma ọ bụ ndị na-egbochi ACE,
• ike nke ihe omume Blocktran emetụtaghị agbụrụ, okike, afọ onye ọrịa,
• a na-anabata ndị saịịnti niile, gụnyere Blocktran. Ọgwụ ndị a kachasị nchebe nke ọgwụ mgbochi oke, ugboro ole ọ na-ebute nsonaazụ ha pere mpe. E jiri ya tụnyere ndị na - egbochi ACE, o yikarịrị ka ịkpasu ụkwara, hyperkalemia, mmeghachi omume nfụkasị ahụ siri ike,
• Ruo ogologo oge, echere na Blocktran anọpụghị iche na metabolism. A maara ugbu a na ọ na-enyere aka belata insulin iguzogide na cholesterol, ya mere enwere ike iji ya mee ihe iji chịkwaa ọbara mgbali n'ime ọrịa shuga mellitus,
• ọgwụ ahụ anaghị emetụta patchial patchial (anaghị akpata ụkwara) yana ọrụ arụmọrụ,
• ndị sartans bụ ndị kachasị asọmpi nke ndị na - egbochi ACE na nkụda obi. E nwere ihe akaebe na losartan na-enye otu ụdị ndụ, na -ewepụta ohere nke nkụchi obi na ọrịa strok, na-eme ka ọnọdụ ndị ọrịa na-arịa nephropathy, hyyoro hypertrophy, yana ndị na-egbochi ACE.
• na nephropathy, iji mbadamba Blocktran ogologo oge nwere ike belata proteinuria site na 35%, belata ihe ize ndụ nke ọdịda akụrụ site na nke ikpeazụ, ọnụ, ogbo site na 28%,
• losartan nwere mmetụta antiarrhythmic,
• ọgwụ nwere mmetụta dị mma na metabolism purine: ọ na-akwalite excretion nke uric acid, na-eme ka ọnọdụ nke ndị ọrịa nwere gout.

Ya mere, ojiji nke Blocktran na omume ulo ogwu ka sara mbara karia akowara ntuziaka.

Kedu ka ọgwụ si arụ ọrụ?

Usoro nke losartan bụ igbochi ndị nabatara ụdị angiotensin II AT-1. Angiotensin II bụ otu n'ime peptides kachasị na - etinye aka na sistemụ nrụgide nke ahụ. Ọ nwere mmetụta ọfụma na ọkwa mgbali: ọ na - egbochi akwara ọbara, na - eme ka nguzogide ha dịkwuo elu, na - akpali mmepụta nke aldosterone (hormone nke na - akpata nguzozi-nnu mmiri), ma na - ebelata mmamịrị.

Mbadamba Blocktran na-eme oke nhọrọ: ha na-egbochi naanị ndị na-anabata angiotensin ndị na-emetụta ihe ndị na-ebute ọbara mgbali elu. N'ihi mgbochi dị otú ahụ, ụda olu vaskụla na-ebelata, nrụgide na-ebelata.

Kedụ nsogbu e kwesịrị iwere Blocktran: A na - achọpụta ọbara mgbali elu ozugbo ogo mgbali elu kwa ụbọchị ruru 140/90. Na mbido, kachasị dị nrị, ogo nke ọrịa, a na-atụ aro ka ndị ọrịa hapụ ifelata, mmega ahụ, na nri. Ọ bụrụ na usoro ndị a anaghị arụ ọrụ, debe ọgwụ ọgwụ mgbochi. Mgbe ị na-ahọrọ otu ọgwụ, ha na-elekwasịkarị anya na akụrụngwa ndị ọzọ. Iji maa atụ, a na-egosi mkpịsị akwara maka nkụchi obi, ndị na - egbochi calcium - mgbe ọ gbasịrị ya. Ọnọdụ nke sartan dị na ọkwa a bụ mgbochi nke ischemia obi. Ndị na-egbochi ACE na-anọchikarị ha ma ọ bụrụ na ha na-akpata nsonaazụ. Dabere na ndị ọrịa, a na-enye iwu losartan ka ọ bụrụ ọgwụ mbụ na-adịghị ahụkebe.

Njirimara ọgwụ ọgwụ nke mbadamba Blocktran:

N'adịghị ka ndị na - egbochi ACE, Blocktran anaghị ebute hypotension na mbido ọgwụgwọ. Mgbe akagbuola mbadamba nkume, nrụgide ahụ jiri nwayọ rute larịị gara aga, ndo dị nkọ anaghị eme.

Ihe ngbanwe

nnukwu ike ọgwụgwụ ọbara,

- enwere ezigbo nsogbu akwara (wepu ihe na-erughi 30 ml / min),

- na-emekotaotu eme eji eme ihe na udiri potassium, ndi na –eme ka udiri ogwu

- dysfunction imeju siri ike (karia isi itolu n'ihe banyere nwatakiri-Pugh), cholestasis,

- afọ ime na oge inye ara,

- gbara afọ 18 (edobebeghị ịdị adị nke nchekwa na ojiji).

- Hypersensitivity na mmiri ọgwụ ahụ, ihe ndị ọzọ ana - akpọ sulfonylamide,

-Anagaghị adị nke lactose, ụkọ lactase, ọrịa glucose-galactose malabsorption.

Etu ị ga-esi

Ofdị irè nke ọgwụgwọ yana mbadamba Blocktran na-adabere n'ụzọ dị mma ịsụ ọgwụ yana nnabata iwu nnabata. Ndị ọrịa edepụtara ọgwụ a na-enwekarị ajụjụ ndị a na-agaghị ekwe nghọta ma ọ bụ na-ezughị ezu na ntuziaka maka ojiji. Ka anyị tụkwasịnụ obi na ha.

Etu esi ahọrọ ezigbo uzo?

Ọgwụ nke ọbara mgbali elu bidoro na 50 mg. Ọ bụrụ na onye ọrịa ahụ na - a diụ ọgwụ - site na 25 mg, na nkụda obi - site na 12.5 mg. A drunkụrụ ọgwụ a n'izu 1, na-elezi ọnọdụ ha na ọkwa nke nrụgide anya. Ọ bụrụ na nrụgide ahụbelatala na ọkwa ahụ (site na 125/75 ruo 140/90, dọkịta ahụ kpebiri), na ọgwụ ahụ anaghị akpata nsonaazụ, a na-eji nwayọọ nwayọọ na-abawanye. Site na mbido izu ọhụrụ, a na-agbakwunye 12.5 mg ma na-achọpụta ihe na-aga n'ihu. N'ọtụtụ ọnọdụ, enwere ike ịbawanye dose ahụ ruo ogo 100 mg. Ọ bụrụ na enyeghị ọkwa nrụgide a chọrọ, nkuzi a na-atụ aro ka iji Blocktran GT dochie Blocktran.

T chọrọ mgbochi nri tupu nri ma ọ bụ mgbe nri gasịrị?

Site n'echiche nke ịdị irè nke ọgwụgwọ, oge nchịkwa adịghị mkpa, ebe ọ bụ na nri adịghị emetụta ogo ịmịkọrọ nke losartan. Agbanyeghị, enwere ike ịnabata ọtụtụ ọgwụ ma ọ bụrụ na ị themụọ ha mgbe ị gachara.

Ọ ka mma ị drinkụ ọgwụ n'ụtụtụ ma ọ bụ na mgbede? Ntuziaka maka iji Blocktran egosighi oge kachasị mma maka ịnata ya. Ebe ọ bụ na nsonaazụ ọgwụ ahụ ezighi ezi (kachasị awa 6 mgbe nchịkwa), enwere ike ịchịkwa mmetụta hypotensive ya. Dịka ọmụmaatụ, ọ bụrụ na nrụgide na-ebili n'ehihie, ọ bụ ihe ezi uche karịa ị toụ mkpụrụ ọgwụ n'ụtụtụ, ọ bụrụ na n'isi ụtụtụ - tupu alakpu ụra.

Ole ka onini ole ị chọrọ iji gwaa ọgwụ kwa ụbọchị?

Maka ọtụtụ ndị ọrịa, otu mkpụrụ ọgwụ dị mma. Ọ bụrụ na dose ahụ karịrị 50 mg, enwere ike ikewa ya abụọ ugboro abụọ.

Dọkịta nke Sciences Medical, Isi nke Institute of Diabetology - Tatyana Yakovleva

Agụọla m ọrịa shuga kemgbe ọtụtụ afọ. Ọ na-atụ ụjọ mgbe ọtụtụ mmadụ nwụrụ, nweekwa nkwarụ karịa n'ihi ọrịa shuga.

Emere m ngwa ngwa izisa ozi ọma - Endocrinological Research Center nke Russian Academy of Medical Sciences jikwaa aka ịmalite ọgwụ na-agwọ ọrịa shuga mellitus kpamkpam. N'oge a, ịdị irè nke ọgwụ a na-eru nso 98%.

Ozi ọma ọzọ: Ministri Ahụike echekwaala maka mmemme pụrụ iche nke na-akwụ ụgwọ ọgwụ dị elu. Na Russia, ndị ọrịa mamịrị ruo Mee Mee 18 (isonye) nwere ike inweta ya - Naanị 147 rubles!

Kedu ọgwụ nsogbu m nwere ike ị drinkụ Blocktran? Ngwakọta kachasị dị irè maka losartan bụ ndị na-emegide calcium na diuretics, nchikota a na-anabata bụ losartan na beta-blockers. Blocktran nwere contraindication maka imekọ ihe ọnụ na ọgwụ ndị nwere ụdị arụmọrụ: sartans ndị ọzọ, ndị na-egbochi ACE. Ojiji ya na ọgwụ ndị na-enye potassium (Veroshpiron) chọrọ njikwa ọzọ n'ihi ihe ọghọm nke hyperkalemia.

Etu esi eji: usoro onunu ogwu na usoro ọgwụgwọ

Anakwere site n’onu ede, agbanyeghi agbanyeghi ube nno, ugboro ole ana anata Blocktran GT - oge 1 kwa ubochi.

Ihe mbido na ndozi bụ 1 mbadamba 1 oge kwa ụbọchị. N'okwu 13 dị iche iche, iji nweta nsonaazụ ka ukwuu, a na-amụba dose ahụ ruo mbadamba abụọ 1 oge kwa ụbọchị. Oke kachasị kwa ụbọchị bụ mbadamba abụọ nke Blocktran GT.

Ọ dịghị mkpa ka ịhazigharị ọgwụ ahụ ka ndị ọrịa agadi na ndị ọrịa nwere nsogbu ịgbazigharị na-adịghị ala ala (CC 30-50 ml / min).

Mbelata ihe ize ndụ nke ọrịa obi na ọnwụ na ndị ọrịa nwere ọbara mgbali elu na mgbali ventricular hypertrophy.

Omume ọgwụ

Ihe ndị mejupụtara Blocktran GT nwere mmetụta antihypertensive na-eme ka ọ dị ala, na-ebelata ọbara mgbali elu (BP) karịa nke ọ bụla n'ime otu. N'ihi mmetụta diuretic ahụ, hydrochlorothiazide na-abawanye ọrụ plasma renin (ARP), na-akpali nzuzo nke aldosterone, na-eme ka mkpokọta nke aigiotensin II ma na-ebelata ọdịnaya potassium. Recenata losartan na egbochi ihe omimi nke aigiotensin nke abuo na, n’ihi nnabata nke aldosterone, nwere ike inye aka belata mmebi nke ihe gbasara potassium na i takingomi.

Hydrochlorogiazide na-akpata ntakịrị mmụba na mkpo uric acid na plasma ọbara, losartan nwere mmetụta uricosuric dị ala na nke dị mkpụmkpụ. Nchikota nke losartan na hydrochlorothiazide na-enyere aka belata ogo hyperuricemia nke diuretic kpatara.

Losartan: Angiotensin II bụ vasoconstrictor dị ike, hormone nke na - arụ ọrụ nke usoro renin-angiotensin-aldosterone, yana njikọ prọfesọ dị mkpa na mmepe nke ọbara mgbali elu. Losartan bụ onye na - emegide ụzọ nnabata nke aigiotensin II (ụdị AT1). Angiotensin II na-ejikọ ndị na - anabata AT1 ndị a hụrụ n'ọtụtụ anụ ahụ (na akwara anụ ahụ dị mma, akwara na obi) ma na - arụ ọtụtụ ọrụ ndu dị mkpa, gụnyere vasoconstriction na mwepụta nke aldosterone. Angiotensin II na - akpalitekwa ịbawanye uru akwara dị mma.

Nsonaazụ

N'ime ọmụmụ ụlọ ọgwụ na losartan / hydrochlorothiazide, ọ nweghị ihe ọghọm metụtara otu ọgwụ ọgwụ a jikọtara. Ọ bụ naanị ndị losartan na hydrochlorothiazide ka emechara ka ihe ọjọọ mee.

N'akụkụ ọbara na sistem lymphatic: ugboro ugboro - anaemia, Shenlane-Genoch purpura, ecchymosis, hemolytic anemia.

Mmeghachi omume nfụkasị: na - adịkarịghị - mmeghachi omume anaphylactic, angioedema, urticaria.

Na akụkụ nke metabolism na nri na-edozi ahụ: ugboro ugboro - anorexia, iwe ọkụ nke gout.

Site na sistemụ akwara: etiti oge - isi ọwụwa, dizzness, ehighị ụra nke ọma, enweghi oge - nchekasị, paresthesia, neuropathy nke ụjọ, ụjọ, migraine, nkụda mmụọ, nchekasị, nsogbu ụjọ, ọgba aghara, ọgba aghara, ịda mba, ụra, ọgba aghara nchekasị .

Site n'akụkụ akụkụ ahụ nke ọhụụ: ọhụhụ - ọhụhụ na-enweghị isi, mmetụta nke nkụ na ọkụ n'anya, conjunctivitis, belata acuity visual.

Site n'akụkụ akụkụ anụ ahụ: ugboro ugboro - vertigo, tinnitus.

N'akụkụ ọbara na sistem lymphatic: ugboro ugboro - agranulocytosis, aplastic anaemia, hemolytic anaemia, leukopenia, purpura, thrombocytopenia.

Mmeghachi omume nfụkasị: na - adịkarịghị - mmeghachi omume anaphylactic.

Site n'akụkụ nke metabolism na nri na-edozi ahụ: enweghi oge - anorexia, hyperglycemia, hyperuricemia, hypokalemia, hyponatremia.

Site na sistem ahụ ụjọ: ọtụtụ mgbe - isi ọwụwa, ugboro ugboro - ọgbụgba, ehighị ụra nke ọma.

Site n'akụkụ akụkụ ahụ nke ọhụụ: enweghi ike oge - enweghi ike ịhụ anya, xanthopsia.

Site na usoro obi: ugboro ugboro - necrotizing vasculitis.

Ntụziaka pụrụ iche

Blocktran GT, yana ụfọdụ ọgwụ na-emetụta sistemụ renin-angiotensin-aldosterone, nwere ike ime ka mkpụkọ ọbara urea na creatinine ọbara dị na ndị ọrịa nwere akwara akwara ma ọ bụ stenosis nke akwara akwara. Mgbanwe ndị a dị na arụ ọrụ akụrụ bụ ndị agbanwere ma kpochapụ mgbe ha kwụsịrị ọgwụgwọ.

Achọghị ọgwụ a ka enye ọgwụ maka mmụba nke Symicomatic na mkpo uric acid yana maka gout.

Mmekorita

Enwere ike inye gị ọgwụ ndị ọzọ na - ere ọgwụ na - ere ọkụ.

Site na iji ya mee ihe n'otu oge na barbiturates, narcotic analgesics, ethanol, orthostatic hypotheisia nwere ike ịmalite. Iji otu oge iji ọgwụ hypoglycemic (maka nchịkwa ọnụ na insulin), enwere ike ịchọrọ ịhazigharị ọgwụ nke hypoglycemic ọgwụ. N'ihi ihe egwu nke etolite lactic acidosis n'ihi ọrụ akụrụ nwere nsogbu, ekwesịrị iji metformnn jiri nlezianya mee ihe mgbe ị na-eji hydrochlorothornazide.

Site na ojiji nke Blocktran GT n'otu oge, ọgwụ ọgwụ ndị ọzọ na - egbochi mkpali, a na - achọpụta mmetụta mmelite.

Mlọ ọgwụ

Mgbe a na-elekọta ya, losartan na-anara mmiri nke ọma na eriri afọ ma metabolized na imeju na ntinye nke CYP2C9 isoenzyme, na-etolite metabolite na-arụsi ọrụ ike (ihe dị ka 14% nke ọgwụ a nabatara na-abanye na ya) na ọtụtụ metabolcologically adịghị arụ ọrụ metabolites. Ya bioavailability ruru 33%. A na-edekọ mmiri kachasị losartan na metabolite ya mgbe elekere 1 na awa 3-4 gachara Blocktran.

Ogo nke jikọtara ihe ndị dị n'ọrụ nke Blocktran na protein ndị na-enye plasma (ọkachasị albumin) bụ ihe dịka 99%. Losartan fọrọ nke nta ka ọ ghara ịbanye n'ime mgbochi ụbụrụ.

Nkeji ọkara ndụ nke losartan bụ awa 1.5-2, na metabolite na-arụ ọrụ nke ọgwụ ya bụ awa 6-9. Ihe dị ka 35% nke dose ahụ wepụtara site na akụrụ, yana ihe dịka 60% site na eriri afọ.

Ọmụmụ nyocha ahụike gosipụtara na ọdịnaya nke losartan na plasma ọbara n'ime ndị ọrịa nwere ọrịa cirrhosis na-abawanye nke ukwuu, yabụ, ndị ọrịa nwere akụkọ banyere ọrịa imeju chọrọ mmezi nke Blocktran gbadata.

Ntuziaka maka iji Blocktran: usoro na usoro onunu ogwu

Ekwesịrị iburu Blocktran ọnụ 1 oge kwa ụbọchị. Nri anaghị emetụta mmịpụta nke ọgwụ.

Site na mgbali ọbara, 50mg kwa ụbọchị ka a na-edenye ya. N'ọnọdụ ụfọdụ, ọ ga - ekwe omume ịbawanye ọgwụ kwa ụbọchị ruo 100 mg na 1-2 usoro.

Na nkụpu obi, ọgwụgwọ na-ebido kwa ụbọchị nke 12.5 mg. Mgbe ahụ, otu ugboro n'izu, a na-amụba dose ahụ dabere na foto ụlọ ọgwụ: nke mbụ ruo 25 mg, emesịa ruo 50 mg.

Ọgwụ nke ụbọchị mbụ maka ndị ọrịa nwere nkụda mmụọ na-anata usoro ọgwụgwọ diuretics dị elu bụ 25 mg.

Site na imeju imeju, itinye uche nke losartan na plasma ọbara na-abawanye nke ukwuu, yabụ, a na-eji Blocktran eme ihe na obere usoro.

Ntuziaka maka iji Blocktran GT

Ekwesịrị ị oụ ọgwụ ahụ otu ugboro n'ụbọchị.

Na ọbara mgbali ike usoro mbụ na usoro mmezi - 1 mbadamba otu ugboro kwa ụbọchị. N'ọnọdụ ụfọdụ, iji rụpụta nsonaazụ ka mma, a na-abawanye usoro ịba ụba gaa mbadamba abụọ otu ugboro n'ụbọchị. Ihe kachasị elu kwa ụbọchị bụ mbadamba ọgwụ abụọ.

Mgbe ejiri ya belata ihe egwu ọrịa obi na onwu na ndi mmadu na ọbara mgbali ike na ịba ụba na ọgwụ mbụ ventricle losartan hà 50 mg otu ugboro n’ụbọchị. Ndị ọrịa nwere 50 mg losartan otu ubochi ike nrụgide ekwesighi iru, nhọrọ nke ọgwụgwọ site na njikọta ka achọrọ losartanusoro onunu ogwu hydrochlorothiazide (12.5 mg), ma ọ bụrụ na ọ dị mkpa, mụbaa usoro onunu ogwu losartanihe ruru 100 mg kwa ụbọchị yana 12.5 mg hydrochlorothiazide kwa ụbọchị. Mgbe ahụ enyere ya ka iwelie onunu ogwu ya rue mbadamba nkume abụọ nke Blocktran GT kwa ụbọchị.

Dodoụbiga ya ókè

N'ihe banyere ịdoụbiga ọgwụ ike ókè, a ga-akwụsị ị useụ ọgwụ ahụ, ekwesịrị inye onye ọrịa ịchịkwa obi na ọrụ ngụgụ, ọgwụgwọ Symptomatic - gastric lavage, mkpocha nsogbu ọgba aghara, akpukpo mmiri. ịba ọcha n'anyana nkụda mmụọ site na usoro ọkọlọtọ.

Omume mmetụta enwere ike

Dabere na ọmụmụ, n'etiti mbadamba ọgwụ mgbochi, sartans bụ ihe e ji amata nke ka mma. Nke a pụtara na ndị ọrịa na-akpọrọ ha ịdọ aka na ntị karịa, o yikarịghị ka ha ga-akwụsị ịgwọ onwe ha. Ihe kpatara ihe ịga nke ọma a bụ ịdị mma nke nchịkwa (naanị 1 oge), ịdị mfe nke nhọrọ dose, ọnụọgụ nke nsonaazụ kachasị nta.

Ntughari nke Blocktran nwere dika placebo (ogwu ogusi). Imirikiti mmetụta dị n ’ọgwụ adịghị ejikọta ya na ahụike adịghị mma, kama ọ na nzaghachi nke anụ ahụ na mbelata ọbara mgbali elu. Dịka iwu, n'ọnwa mbụ nke ọgwụgwọ hypertensives na-enwe mmetụta ka njọ, onye nrụgide ogologo oge nọ n'ọkwa dị elu.

Mmetụta ọghọm nke, mgbe ị na-eji Blocktran, mere ọtụtụ oge karịa na placebo otu:

A na-anabata ndị ọrịa hypertensive na ọrịa akụrụ, ndị ọrịa agadi, mbadamba Blocktran yana ndị ọrịa ndị ọzọ. Site na ọrịa imeju na ọrịa imeju, ihe ize ndụ nke ịdoụbiga mmanya ókè dị elu n'ihi mmebi nke metabolism nke losartan. N'ihe banyere oke nnyefere, hypotension, tachycardia, bradycardia ga-ekwe omume.

Ndị ọrịa nwere nkụda mmụọ, ndị ọrịa mamịrị na-enwe nephropathy, ndị na-a takingụ Veroshpiron ma ọ bụ potassium na-enwe ihe ize ndụ dị elu nke hyperkalemia. Enwere ike icheta ọnọdụ a maka adịghị ike akwara, nsogbu nke mpaghara, nsogbu obi. Ọ bụrụ na achọpụtara hyperkalemia (potassium> 5.5 dị ka nyocha), a ghapụrụ Blocktran.

Analogs na nnọchi

A na - emepụta ọtụtụ analogs nke Blocktran site na ọtụtụ ndị na - emepụta ọgwụ. Na-ekpe ikpe site na nyocha nke ndị ọrịa nwere oke ume, ọgwụ ndị a bụ ihe a ma ama na Russia:

Ndị nọchiri Blocktran na mmetụta kachasị nso bụ valsartan (mbadamba Valsacor, Diovan, wdg), candesartan (Ordiss), telmisartan (Mikardis, Telzap).

Nkọwapụta na ọgwụ ọgwụ ọgwụ

Iji ngwaahịa ahụ na-enyere aka belata ihe mgbochi nke arịa ụsọ mmiri, belata ogo ịhapụ aldosterone na angiotensin n'ọbara. Mbadamba Blocktran, ntuziaka maka ojiji nke nwere ozi zuru ezu banyere ọgwụ ahụ, ka ndị dibia bekee debere iwu imezi ọrụ obi ndị agadi na ndị okenye. Otu mbadamba ihe dị 50 mg nke losartan tinyere ihe inyeaka, gụnyere lactose, stachi, magnesium stearate na ọtụtụ ihe ndị ọzọ.

Dị Mkpa! Emepụtara ọgwụ Blocktran GT iji belata nrụgide ma weghachite ya na nkịtị na ndị ọrịa na-arịa ọtụtụ ọrịa ọrịa ama ama. Ngwa ndị nọ n'ọrụ - losartan na hydrochlorothiazide - nwere mmetụta dị mgbagwoju anya.

N'ime usoro ị theụ ọgwụ ahụ na ndị ọrịa, a na-ahụta mbelata nke ibu na akwara obi, nke na-egbochi mmepe nke mmebi myocardial hypertrophic. Losartan na-enyekwa nsị diuretic ma ọ dịghị egbochi enzyme AP nke na-emebi bradykinin. N'ihi nke a, Blocktran anaghị akpasu mmepe nke ụkwara nkụ, dịka ọgwụ ndị ọzọ nke otu otu.

Mmetụta akpọpụtara pụtara awa 6 mgbe nchịkwa gasịrị, mgbe ahụ ọkwa nrụgide na-ebelata ụbọchị ma nọgide na-enweta uru a na-anakwere. N'iji ya mgbe niile, ọgwụ ahụ nwere mmetụta hypotensive mgbe ọnwa gasịrị.

Obi

Kinetic edinam

Dabere na ntuziaka maka ojiji a na-etinye ọgwụ ahụ ngwa ngwa site na nri digestive na bioavailability nke opekata mpe 30%. Concentta ụta nke ihe arụ ọrụ ruru ogo ya otu elele mgbe nchịkwa gasịrị. Ngwa nke mbadamba n’ime sel imeju na-agbanwe ka ọ bụrụ metabolites na-akpalite oke hypotensive. A na-etinye metabolite n’ime ọbara n’ime awa anọ gachara. Losartan na-apụ apụ n'ahụ mgbe awa 1.5-2 gasịrị, ngwaahịa metabolic ya na-agbadata nwayọ karịa, oge ntụgharị ha na-ewe awa 6-9. Ọ bụ akụrụ na eriri afọ ga-ewepụ ihe ndị dị ọtụtụ.

Ihe ngosi na contraindications

A na-enye ọgwụ Blocktran na analogues nke ọgwụ ahụ naanị na nkwenye dọkịta nwere nyocha nke egosipụtara. Theụ ọgwụ ahụ bụ ihe amamihe dị na ọbara ọgbụgba na akwara obi. Ọgwụ nwere ike ịbụ akụkụ nke usoro ọgwụgwọ dị mgbagwoju anya maka ndị ọrịa nwere ntachi obi na ndị na-egbochi ACE.

Ọ na-ebelata ihe ize ndụ nke ịmalite ọrịa dị egwu nke obi na akwara ọbara, ọnụego ọnwụ na ndị ọrịa na-arịa ọbara mgbali elu yana mgbakwunye hypertrophy nke aka ekpe. Ndepụta nke contraindications maka ojiji gụnyere:

• hypotension
• akpịrị ịkpọ nkụ na hyperkalemia,
• afọ ruo afọ 18
• ime na lactation
• oke uche nke ihe na mejupụtara ngwaahịa a,
• mmụba n'ọnụ ọgụgụ potassium ion n'ọbara ọbara,
• akpịrị ịkpọ nkụ.

A na-enye ndị ọrịa nwere nsogbu ọrụ akụrụ na umeji Blocktran na usoro ha nwere oke iji zere mmebi. Ọnụ ọgụgụ mbadamba oge a na-agwọ ọrịa kwesịrị ịbụ ihe kwesịrị ịdị, ihe ndị mejupụtara ya nwere ike ibute nnukwu nsogbu ruo ọnwụ.

Erere ọbara ọgbụgba

Ofzọ nke ngwa

Mgbe a bịara n'ihe Blocktran na-enyere aka, ọ bara uru ịkọwapụta otu esi eji ya. A ga-emerịrị ngwa ahụ otu ugboro n'ụdị ọnụ, ọ na-akarịghị usoro nke dọkịta nyere na ndenye ọgwụ ahụ. A na-enye ndị ọrịa nwere ọbara mgbali elu 50 mg kwa ụbọchị. Ọ bụrụ na ebumnuche a rụpụta ihe akpọrọ akpọrọ, ego a na-abawanye ruo 100 mg kwa ụbọchị ma ọ bụ nke 50 mg ekewa ya mgbe ewere ya ugboro abụọ n'ụbọchị. A na-enye ndị ọrịa nwere nkụda mmụọ ọbụlagodi 12.5 mg kwa ụbọchị.

Ọtụtụ mgbe, usoro ịba ụba na-abawanye na oge nke otu izu ka ọkwa dị elu, ụkpụrụ ikpeazụ bụ ma ọ dịkarịa ala 50 mg kwa ụbọchị. Ọ bụrụ na onye ọrịa ahụ ewere ọgwụ ọ ofụ buru ibu, ọgwụ a na-agbadata ọgwụ ahụ ruo 25mg kwa ụbọchị. Site na iji ọrịa imeju, a na-eji nlezianya na obere usoro iji dochie Blocktran. Ekwesịrị iburu n'uche na n'oge ọgwụgwọ a chọrọ ka ọ na-enyocha ọkwa nke potassium na ọbara mgbe niile, ọ kachasị ndị ọrịa afọ ma ọ bụ nsogbu akụrụ.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Nzuzo nke Blotran bu ka eme ka obara di ala nke oma ma nwee ike inyere onye ọrịa aka ka o na-ele onunu ogwu nke dọkịta nyere. N'ọnọdụ ị anụbiga mmanya ókè, a na-akwụsị nnabata ahụ, a na-achọpụta obi onye na-arịa ya na ngụgụ, a na-edenyekwa usoro ọgwụgwọ Symptomat. Nke a na-agụnye lavage gastric ọkọlọtọ, mkpocha nsogbu electrolyte, coma na akpịrị ịkpọ nkụ, nhọpụta nke ọgwụ iji mee ka nsogbu dịkwuo elu.

Ndepụta nke nsonaazụ ya gụnyere:

• nsogbu ihi ụra, isi ọwụwa na nkụda mmụọ, nrụrụ ụbụrụ, oke ike ọgwụgwụ na ịda mba,
• nkwarụ anya, nsogbu ụfụ, tinnitus,
• ngwo, akọrọ ụkwara, rhinitis,
• dyspepsia, ụkọ ma ọ bụ abawanye na agụụ, gastritis, afọ ntachi, mmetụta nke akpịrị ịkpọ nkụ,
• mgbu na nkwonkwo akwara nke ụkwụ na azụ, ngosipụta nke ogbu na nkwonkwo,
• nsogbu mgbali, arrhythmia, angina pectoris ma ọ bụ tachycardia,
• mbufụt nke urinary tract.

Patientsfọdụ ndị ọrịa nwere ike ịnwe mmeghachi omume nfụkasị, edema, ihe ọkụ ọkụ, ọmịiko gabigara ókè maka ìhè anyanwụ. Ọtụtụ mgbe, ọgwụ a na-anabata nke ọma na ọkwa niile nke nchịkwa, ya mere enwere ike ịde ya ọgwụ na-enweghị mgbochi na enweghị ọgwụ mgbochi doro anya. Imirikiti nsonaazụ na-apụ n'anya mgbe ịkwụsị ọgwụ, nke analog dochie ya.

Medicationakingụ ọgwụ

Ndụmọdụ pụrụ iche

Ọ bụrụ na akpịrị na-arịa ọrịa mmiri n'otu oge ahụ ọgwụgwọ Blocktran, ọ ga-adị mma ịmalite ị theụ ọgwụ na obere usoro. Site na stenosis akwara akụrụ, ọgwụ ahụ nwere ike ime ka ịta ụba nke creatinine na urea na ọbara. Mgbe ị na-a theụ ọgwụ ahụ, ọ dị mkpa iji nyochaa oge niile mkpokọta potassium n'ime ọbara, nke a metụtara ndị agadi na ndị ọrịa nwere nsogbu gbasara akụrụ.

Ọdịda ntaramahụhụ abụghị ihe mere iji belata usoro onunu ogwu, naanị ihe ọ dị mkpa ka e belata. Edeghị ọgwụ ahụ ruo mgbe ọ dị afọ 18, a na-anabata ya maka ndị agadi, na-eburu n'uche nyocha nke steeti usoro ahụ obi ha, nyocha ọbara na ihe ndị ọzọ na-egosi. Enwere ike ịzụta Blocktran n'ụlọ ahịa ọgwụ naanị site na ndenye ọgwụ.

Ihe ngosi zuru ezu banyere ogwu a ka egosiputara ya na vidiyo di n'okpuru:

Ọbara mgbali elu - gịnị ka ọ bụ?

Site n'okwu dị ka “ọbara mgbali elu” pụtara mmadụ ịbawanye ọkwa ọbara mgbali elu karịa 140/90 mm Hg. Art. Mgbe ụfọdụ, ọ bụ usoro izizi ma ọ bụ nnwere onwe na-etolite na onye ọrịa na-enweghị ihe ọ bụla akọwapụtara (ọbara mgbali dị mkpa). Ma oge ụfọdụ ọ na-aghọ ihe mgbagwoju anya ma ọ bụ nsonaazụ nke ọrịa ndị ọzọ (ọbara ọgbụgba na -akpata). Ọrịa ọrịa obi bụ ihe a na - ahụkarị, ọ bụ na ọ na - eme ka nde mmadụ nde mmadụ gburugburu ụwa na-agakwuru dọkịta kwa ụbọchị maka enyemaka. Ọ bụ ole na ole maara ihe ọ bụ.

Ọbara mgbali elu abụghị naanị mmụba mgbali elu. Ọrịa ahụ na-ekpuchi ụdị ọrịa dịgasị iche iche site na sistem akwara, akwara ọbara, akụrụ na obi, nke metụtara ahụike onye ọrịa.

Ọbara mgbali elu bụ otu n'ime ihe na - ebute ọnwụ n’etiti ndị na - eto eto nwere ike, ebe nsonaazụ kachasị njọ nke ọrịa dị otú a bụ imebi ọbara mgbasa nke ụbụrụ ma ọ bụ ọrịa strok.

Ngwakọta ọgwụ ahụ

Otu mbadamba ọgwụ nke Blocktran gụnyere milligrams potassium nke losartan potassium. Ihe ndi ozo: microcrystalline cellulose, lactose monohydrate, povidone di omimi pere mpe, sodium carboxymethyl stachi, silicon dioxide, sitriji nduku, steeti magnesium. Ihe mejupụtara Shell: titanium dioxide, ihe eji acha odo odo, ọdịda anyanwụ, hypromellose, talc, copovidone, polysorbate 80.

Otu mbadamba nkume nke Blocktran GT gụnyere hydrochlorothiazide (12.5 mg) na potassium losartan (50 mg). Ihe ndi ozo: microcrystalline cellulose, lactose monohydrate, povidone di omimi pere mpe, sodium carboxymethyl stachi, stachi nduku, silicon dioxide, magnesium stearate.

Ihe mejupụtara nke membrane ahụ gụnyere hypromellose, polydextrose, red dye carmine, ọkara chain triglycerides, talc, maltodextrin, titanium dioxide.

Kedu ihe bụ ọgwụ pịnyere Blocktran GT? A ga-atụle nke a ma emechaa.

Kpachara anya ọgwụ

N'iji nlezianya mee ihe, a na-eji Blocktran GT rụọ ọrụ n'ọnọdụ ndị a:

• Mmebi nke mmiri-electrolyte nguzogide, ọmụmaatụ, megide ndabere nke vomiting ma ọ bụ afọ ọsịsa (hyponatremia, hypokalemia, hypomagnesemia, hypochloremic alkalosis).
• N'ime ndị ọrịa nwere akụrụngwa akụrụngwa (mwepụ nke creatinine karịrị 30 ml / min), na stenosis nke akwara nke otu akụrụ (otu) na ọgbụgba akwara akwara akụrụ.
• Bụrụ na arụ ọrụ imeju adịghị mma (n'okpuru isi 9 dabere na Child-Pugh).
• Na ọnụnọ nke gout na / ma ọ bụ hyperuricemia, hypercalcemia, ọrịa shuga mellitus, na akụkọ ihe mere eme na-akpata nfụkasị (angioedema mepụtara na ụfọdụ ndị ọrịa n'oge gara aga site n'iji ọgwụ ọjọọ ndị ọzọ, gụnyere ndị na-egbochi ACE), ụkwara ume ọkụ, yana usoro pathologies nke anụ ahụ na - ejikọta (gụnyere sistemu lupus erythematosus) .
• Na hypovolemia (gụnyere megide ndabere nke nnukwu ọgwụ ịba ọcha n'anya),
• Ndị ọrịa nwere nnukwu ọgụ nke glaucoma nkuku.
• Mgbe edepụtara ya na ndị ọrụ mgbochi mkpali na-egbochi steroid, gụnyere ụdị 2 nke cyclooxygenase inhibitors, na cardiac glycosides.
• Ndị ọrịa nwere ọrịa obi, ndị agadi.

Usoro onunu ogwu

A na-eji ngwá ọrụ "Blockchain GT" nke nwere ọbara mgbali elu n'ime anụ ahụ, n'agbanyeghị nri nri, ugboro ole nchịkwa - otu ugboro n'ụbọchị.

Nlekọta ya na usoro ọgwụgwọ nke mbụ ha na otu mbadamba otu ugboro kwa ụbọchị. N'ọnọdụ ụfọdụ, iji wee nweta nsonaazụ ka ukwuu, ọ na-abawanye na abuo abụọ otu ugboro n'ụbọchị. Usoro kachasị elu kwa ụbọchị bụ mbadamba abụọ nke Blocktran GT.

Adjusthaghari etu esi eme ndi agadi ma obu ndi oria ndi mmadu na ahaghi ihe na adighi nma.

Iji belata ohere nke ịmalite ọrịa obi na ọrịa obi na ọrịa na ndị ọrịa nwere ọbara mgbali elu ventricular na ọbara mgbali elu, a na-enye ọgwụ ọgwụ dịka atụmatụ dị n'okpuru. Ọkọlọtọ nke usoro nke Blocktran GT bụ 50 mg otu ugboro kwa ụbọchị. Ndị ọrịa na-enweghị ike inweta nrụgide nkịtị ka ha na-ewere ụdị losartan dị mkpa ịhọrọ ọgwụgwọ site na ijikọta losartan na obere hydrochlorothiazide, ọ bụrụ na ọ dị mkpa, a na-abawanye usoro nke losartan na 100 mg n'otu oge yana 12.5 mg nke hydrochlorothiazide kwa ụbọchị, wee nwekwuo dose ahụ mbadamba abụọ (ngụkọta nke milligrams 25 nke hydrochlorothiazide na 100 milligram nke losartan otu ugboro n'ụbọchị).

Mmeghachi omume na-adịghị mma

Kedu ihe mmetụta dị n'akụkụ GT Blocktran? Nkewa nke ihe ojoo adighi nma bu nke eji aru oru ndi World Health Organisation guzobere.

N'ime ule nke ụlọ ọgwụ nwere hydrochlorothiazide / losartan, enweghị mmetụta ọ bụla akọwapụtara na njikọta njikọ a. Ihe ọghọm bụ naanị ndị a ga-atụle ma emesịa (mgbe ị na-ekiri hydrochlorothiazide na losartan iche).

A hụrụ mmetụta ndị edepụtara n'okpuru ebe a na-eji hydrochlorothiazide na losartan na monotherapy.

Mmeghachi omume ọjọọ na Losartan

Sistemu Lymphatic na ọbara: oge ​​ụfọdụ - anaemia hemolytic, ecchymoses, Shenlein-Genoch purple, anaemia.

Mmeghachi omume nfụkasị: na - adịkarịghị - urticaria, angioedema, mmeghachi omume anaphylactic.

Site n'akụkụ nri nri na metabolism: ugboro ugboro - njọ nke akparamagwa gout, anorexia.

Site na sistemụ akwara: etiti oge - nchekasị nchekasị, nchekasị, nsogbu ihi ụra, paresthesia, iro ụra, neuropathy nsogbu, obi erughị ala, ọgba aghara, migraine, nsogbu ụjọ, nkụda mmụọ, nchekasị, nchekasị, enweghị mgbe ọ bụla, ụra, isi ọwụwa, isi ọwụwa. .

Na akụkụ nke akụkụ ahụ nke visual: oge ​​na - adịghị ahụ anya na nkụ dị n'anya, ọhụhụ ụzọ, belata acuity visual, conjunctivitis.

Site na akụkụ ahụ nke auditory: ugboro ugboro - tinnitus, vertigo.

N’akụkụ akụkụ akụkụ iku ume: oge ​​- ụkwara, imi mkpọchi, akụkụ okuku ume na-efe efe (pharyngitis, sinusitis, sinusopathy, akpịrị mgbu, oke ahụ ọkụ), adịghị ala ala - ahụ erughị ala na pharynx, imi afọ, rhinitis, bronchitis, dyspnea, laryngitis pharyngitis.

Site na akụkụ eriri afọ: oge ​​- mgbaàmà nke dyspeptik, afọ ọsịsa, mgbu nke afọ, ọgbụgbọ, ugboro ugboro - eze mgbu, akpịrị akọrọ nke ọnya ọnya, afọ ntachi, gastritis, flatulence, vomiting.

Usoro akwara: ure na ikpere, ubu, ogwe aka, ọrịa ogbu na nkwonkwo, ọrịa akwara, ike ọgwụgwụ, olu mgbu, nkwonkwo akwara, mgbe mgbe mgbu na ụkwụ na azụ, myalgia, cramps.

Site n'akụkụ nke usoro obi na ọbara: ugboro ugboro - ọgbụgba orthostatic hypotension, hypotension arterial, brady ma ọ bụ tachycardia, palpitations, angina pectoris, arrhythmias, ọkwa II nke AV ngọngọ, mgbu obi, vasculitis, infarction myocardial, ihe omume cerebrovascular.

Site na usoro mkpụrụ ndụ: enweghi oge - enweghi ike, belata libido, ọrịa urinary na-arịa, urination ugboro ugboro, nocturia.

Site na akpụkpọ ahụ na - emegiderịta: ugboro ugboro - erythema, akpụkpọ akọrọ, ọbara "ọkụ" ruo anụ nke ihu, dermatitis, photoensitivity, alopecia, itching nke anụ ahụ, ọsụsọ excessiveụfe, anụ ahụ ọkụ.

Ngosiputa ndi ozo: oge ​​mgbe - oke ike, asthenia, ugboro ugboro - ahuhu, mbufụt nke ihu.

Ihe ngosi nke ulo-akwukwo: ugboro ugboro - ihe di elu nke creatinine na urea, oge obula - mbelata hemoglobin na hematocrit, hyperkalemia, nke di obere - karia oru mmeju nke imeju.

Na hydrochlorothiazide

Sistemu Lymphatic na ọbara: obere oge - thrombocytopenia, agranulocytosis, purpura, aplastic anaemia, leukopenia, hemolytic anemia.

Mmeghachi omume nfụkasị: obere oge - mmeghachi omume anaphylactic.

Oriri na-edozi ahụ na metabolism: enweghi oge - hyponatremia, anorexia, hypokalemia, hyperglycemia, hypokalemia, hyperuricemia.

Site na usoro ụjọ ahụ: nwa oge - ehighị ụra nke ọma, ọgbụgbọ, mgbe mgbe - isi ọwụwa.

Site n'akụkụ akụkụ akụkụ ahụ nke visual: ugboro ugboro - xantopsia, ntụpọ nke adịghị ahụ anya.

Site na sistemu nke obi na arịa ọbara: adịkarịsịrị - ịrịa vasculitis.

Akụkụ akụkụ iku ume: oge ​​ụfọdụ - akụkụ akwara umeji, oyi baa, ọrịa iku ume.

Usoro nri: dịkarịsịrị - sialodenitis, pancreatitis, chorasis intrahepatic (jaundice), mgbakasị ọnya afọ, ọnya ọgbụgba na - egbu egbu, ọgbụgbọ, jaundice, vomiting, afọ ntachi, afọ ọsịsa.

Site na anụ ahụ na akpụkpọ anụ subcutaneous: ugboro ugboro - urticaria, photoensitivity.

Site na mọzụlụ: akwara - akwara olu.

Site na sistemụ urinary: adịkarịghị - arụ ọrụ akụrụngwa arụ ọrụ, glucosuria, ọdịda akụrụ, intephitial nephritis.

Nsogbu izugbe: adịkarịghị - ahụ ọkụ.

Y’oburu na enweigha ahia ahia hydrochlorothiazide / losartan, oputara na nsogbu ndi ozo.

• site na nri digestive - obere ịba ọcha n'anya,
• Nyocha nyocha nke ụlọ nyocha: adịkarịghị - ụba ọrụ transaminase ọrụ, hyperkalemia.

Nyocha Ọgwụ

Nyocha banyere GT Blocktran na-agba akaebe na ikike ya dị elu iji belata nrụgide, mana n'otu oge ahụ, nsonaazụ na-apụta mgbe ị na-eji ọgwụ ahụ mgbe mgbe, tumadi mgbu na ike ọgwụgwụ.

Ndị mmadụ na-ekwu na ọgwụ ahụ dị irè, enwere mgbanwe dị mma nke steeti. Naanị nsogbu nke na-amasị ọtụtụ ndị ọrịa bụ enweghị ọgwụ na ụlọ ahịa ọgwụ, ọ na-apụ n'anya na mberede maka ihe amaghị.

Mgbe ụfọdụ, a na-ahụta ịdị elu nke ọgwụ ka oge na-aga, mana mgbe otu afọ gasịrị, ọ na-ebelata ike ya.

Ọnụahịa nke Blocktran GT na Russia na-amalite na 160 rubles. Ọ dabere na mpaghara na netwọọ ahịa ọgwụ.