Ntuziaka maka insulin Tujeo na analogues na ọnụahịa na nyocha nke endocrinologists
Toujeo SoloStar bụ glargine ọhụụ na-arụ ọrụ ogologo oge nke Sanofi mepụtara. Sanofi bụ nnukwu ụlọ ọrụ na-emepụta ọgwụ na-emepụta insulins dị iche iche maka ndị ọrịa mamịrị (Apidra, Lantus, Insumans).
Na Russia, Toujeo gafere aha ndebanye aha n'okpuru aha "Tujeo." Na Ukraine, a na-akpọ ọgwụ ọria mamịrị ọhụrụ Tozheo. Nke a bụ ụdị analog nke Lantus dị elu. Ezubere maka ụdị okenye 1 na ụdị ọrịa shuga 2.
Uru kachasị nke Tujeo bụ profaịlị na-enweghị atụ na ogologo oge ruru 35 awa.
Nnyocha e mere egosiwo na Toujeo gosipụtara njikwa glycemic dị mma na ụdị 1 na ndị ọrịa shuga 2. Mbelata nke ọkwa hemoglobin glygine dị na insulin glargine 300 IU adịghị iche na Lantus.
Onu ogugu ndi mmadu ruru otutu aka nke HbA1c bu otu, njiko nke gluu nke insulins ahu dika atule.
N'iji Lantus, Tujeo nwere nnabata insulin na-eji nwayọ nwayọ ewebata, yabụ uru dị ukwuu nke Toujeo SoloStar bụ mbelata nke ibute ọrịa hypoglycemia (ọkachasị n'abalị).
Nchịkọta obere maka iji Tujeo
Ọ dị mkpa ịgbanye insulin n'ime obere oge otu ugboro n'otu oge. Ebughịbe maka nchịkwa mgbochi. A na-ahọpụta usoro na oge nchịkwa otu otu site na dọkịta gị na - eleta anya mgbe ọ bụla ị na - enyocha glucose ọbara.
Ọ bụrụ na ndu ma ọ bụ oke ahụ gị gbanwere, enwere ike ịchọ ndozi ya. A na-enye Toujeo ndị ọrịa mamịrị timedị 1 otu oge kwa ụbọchị yana insulin ultrashort injection na nri. Mpempe ọgwụ glargin 100ED na Tujeo bụ ndị na - abụghị bioequurate na ndị na - agbanwe agbanwe.
A na-eme ntụgharị site na Lantus site na ngụkọta nke 1 ruo 1, insulins ndị ọzọ na-eme ogologo oge - 80% nke kwa ụbọchị.
Aha insulin | Ihe eji arụ ọrụ | Emeputa |
Lantus | glargine | Sanofi-Aventis, Germany |
Tresiba | deglutec | Novo Nordisk A / S, Denmark |
Levemir | detemir |
Njirimara na usoro nchịkwa insulin Tujeo si arụ ọrụ
A na-eji ọgwụ glycemic dị iche iche agwọ ọrịa shuga. Sanofi weputara ọgwụ ọhụụ, Tujeo Solostar, nke sitere na insulin.
Tujeo bụ insulin na-arụ ọrụ nke ukwuu. Na-achịkwa ọkwa glucose ụbọchị abụọ.
A na-etinye ọgwụ ahụ nwayọ nwayọ, na-ekesa ngwa ngwa na ngwa ngwa metabolized. Tujeo Solostar na-anabata nke ọma ma belata ihe ize ndụ nke hypoglycemia nke ehihie.
"TujeoSolostar" - ọgwụ nke sitere na insulin na-arụ ọrụ ogologo oge. Ezubere ya maka ịgwọ ụdị ọrịa shuga 1 na ụdị ọrịa shuga 2. Ọ gụnyere ihe mejupụtara Glargin - ọgbọ ọhụrụ nke insulin.
Ọ nwere mmetụta nke glycemic - belata shuga na-enweghị mgbanwe ọkụ. Ogwu ahu nwere udiri ka nma, nke n’enye gi ohere ime ka ihe ghara idi nma.
Tujeo na-ezo aka na insulin na-adịte aka. Oge ihe omume sitere na awa 24 ruo 34. Ihe dị n'ọrụ ahụ yiri insulin. E jiri ya tụnyere nkwadebe ndị yiri ya, ọ na-agbakarị ọsọ - ọ nwere nkeji 300 / ml, na Lantus - 100 nkeji / ml.
Emeputa - Sanofi-Aventis (Germany).
Mara! Ọgwụ ndị a na-ahụ maka glargin na-arụ ọrụ nke ọma ma anaghị akpata shuga na mberede.
Ọgwụ nwere mmetụta dị ala na-ebelata shuga site na ịhazi metabolism. Na-eme ka njikọ protein na-abawanye, na-egbochi nguzobe shuga n’imeju. Na-akpali nnakwere glucose site na anụ ahụ.
A na-etisasị ihe ahụ na gburugburu acidic. Ji nwayọọ nwayọọ na-etinye obi gị dum, kesaa ma kesaa ngwa ngwa. Ọrụ kachasị bụ awa iri atọ na isii. Iwepu ọkara ndụ dị ka awa iri na itoolu.
Insulin nke Toujeo: analogues ohuru na onu ahia
Taa n'ụwa, enwere mmụba dị ukwuu na ọnụ ọgụgụ ndị na-arịa ọrịa shuga. Dị ka amụma si kwuo, ka ọ na-erule 2035 ọnụ ọgụgụ ndị ọrịa mamịrị nọ na mbara ala a ga-abawanye site na abụọ na ọnụ ọgụgụ karịa ihe karịrị ọkara ijeri ndị ọrịa. Onu ogugu onu ogugu a gha eme ka ndi ulo oru ogwu meputa ogwu ohuru ohuru iji luso udiri oria a isi ala.
Otu n'ime mmepe ndị a na - adịbeghị anya bụ ọgwụ Toujeo, nke ụlọ ọrụ German Sanofi mepụtara site na insulin glargine. Ihe mejupụtara a na-eme ka Tujeo nwee insulin basal dị elu ma na-arụ ọrụ ogologo oge nke na-enyere aka ịchịkwa ọkwa shuga dị ọbara n'ụzọ dị mma, na-ezere mgbanwe mberede.
Uru ọzọ nke Tujeo bụ ihe fọrọ nke nta ka ọ bụrụ enweghị mmetụta nke nsonaazụ yana nnukwu ihe nkwụghachi ụgwọ. Nke a na - enyere aka igbochi mmepe nke nnukwu nsogbu na ọrịa shuga, dịka mmebi nke akwara obi na sistem, nke nwere ike ibute ọhụhụ ụzọ, mmebi nke oke yana nsogbu n'ọgbaze.
Nke a pụtara na ụdịrị ụlọ ahụ bụ ihe kacha mkpa maka ọgwụ mgbochi ọrịa, ebe ọ bụ na ihe ndabere maka ọgwụgwọ ọrịa shuga bụ mgbochi ọfụma na-egbochi mmepe nke nsonaazụ ndị dị ize ndụ nke ọrịa ahụ. Mana iji ghọta nke ọma etu Tujeo si arụ ọrụ yana etu o si dị iche na analogues ya, odi nkpa ikwu okwu banyere ogwu a.
Atụmatụ na Uru
Tujeo bụ ọgwụ zuru ụwa niile dabara nke ọma maka ọgwụgwọ ọgwụgwọ na ndị ọrịa nwere ọrịa shuga 1 na ụdị 2. A na-eme ka ihe ndị insulin na-arụ ọrụ nke ọgbọ ikpeazụ, glargin 300, nke bụ mpaghara ya, nke bụ akụrụngwa kachasị mma maka nguzogide insulin siri ike.
Na nmalite oria a, ndi oria nwere oria na - adighi eme insulin, nwere ike ime ya naanị site na iji ogwu eme ka mmanu daa.Ma ka obula mgbe ogbaara oria a, ha gha achoro inje insulin nke basal, nke kwesiri inyere ha aka iguzogide mmanu glucose na agam.
N'ihi nke a, ha na-eche nsogbu niile metụtara ọgwụgwọ insulin ọgụ, dị ka ịba ụba ma mwakpo hypoglycemia ugboro ugboro.
Na mbu, iji belata nsonaazụ insulin, ndị ọrịa na-agbaso ezigbo nri ma na-eme ọtụtụ mmega ahụ kwa ụbọchị. Mana imata analogues nke insulin ọhụụ, dị ka glargine, mkpa maka ịchịkwa ibu dị ogologo oge na ịdị njikere ịkwụsị ọgụ nke hypoglycemia kpamkpam kpamkpam.
N'ihi mgbanwe dị ala, ogologo oge nke ime ihe, na ịhapụ nkwụsi ike nke anụ ahụ n'ime ọbara, glargine adịkarịghị akpata mmiri shuga dị ala ma ọ dịghị enye aka n'inwe oke ahụ.
Nkwadebe niile dabere na glargine dị nchebe maka ndị ọrịa, ebe ọ bụ na ha anaghị ebute shuga dị njọ na shuga ma na-echekwa sistemụ akwara kachasị mma, dịka ọtụtụ ọmụmụ gosiri. Na mgbakwunye, ojiji nke glargine kama detemir na ọgwụ insulin na-enyere aka belata ụgwọ ọgwụgwọ maka ihe fọrọ nke nta ka ọ bụrụ 40%.
Toujeo abụghị ọgwụ mbụ nwere ụmụ irighiri glargine. Eleghi anya mbu mbu nke glargargin bu Lantus. Agbanyeghị, na Lantus, ọ dị na mpịakọta nke 100 PIECES / ml, ebe ọ bụ na Tujeo itinye uche ya okpukpu atọ - 300 PIECES / ml.
Yabụ, iji nweta otu insulin Tujeo insulin, ọ ga - ewekarị okpukpu atọ karịa Lantus, nke na --eme ka injections ghara inwe mgbu n'ihi oke mbelata mpaghara mpaghara ahụ. Na mgbakwunye, obere olu nke ọgwụ ahụ na-enye gị ohere ịchịkwa usoro insulin n'ime ọbara.
N'iji obere ebe mgbakwụnye, ịmịpụta ọgwụ sitere na anụ ahụ dị n'okpuru nwayọ na nwayọ nwayọ. Ngwongwo a na-eme Tujeo n’enweghi ike ana insulin insulin, nke na enyere aka idobe shuga n’otu otiti ma gbochie mmepe nke hypoglycemia.
N'icheta glargin 300 IU / ml na glargin 100 IU / ml, anyị nwere ike iji obi ike kwuo na ụdị insulin nke mbụ nwere profaịlụ mara mma na-arụ ọrụ na ogologo oge, nke bụ 36 awa.
Ngosiputa kachasi nma na nchekwa nke glargine 300 IU / ml gosiputara n’oge ihe omumu a bu nke udiri oria 1 nke oria di iche iche n’abia.
Ọgwụ Tujeo nwere ọtụtụ nyocha dị mma, ma ndị ọrịa ma ndị dọkịta na-agwọ ha.
Ntuziaka maka iji ọgwụ ahụ
Toujeo dị n'ụdị nke mmezi doro anya, akpọchiri na katriiki iko 1.5 ml. A na-etinye katriiki n’onwe ya n’ime mkpụrụ akwụkwọ sirinji maka otu oge. N'ime ụlọ ahịa ọgwụ, a na-ere ọgwụ Tujeo na igbe kaadi, nke nwere ike ịnweta pensụ 1.3 ma ọ bụ 5.
A ga-enye insulin tual basal otu ugboro kwa ụbọchị. Agbanyeghị, enweghị ntuziaka akọwapụtara maka oge kachasị mma maka inje. Onye ọrịa ahụ n'onwe ya nwere ike ịhọrọ mgbe ọ ga-akara ya mma inye ọgwụ ahụ - n'ụtụtụ, n'ehihie ma ọ bụ na mgbede.
Ọ dị mma ma ọ bụrụ na onye ọrịa shuga nwere ike banye insulin Tujeo n'otu oge. Mana ọ bụrụ na echezọ ma ọ bụ na ọ nweghị oge iji gbaa ntụtụ n’oge, n’oge nke a, nke a agaghị enwe nsogbu ọ bụla maka ahụ ike ya. N'iji ọgwụ Tujeo, onye ọrịa ahụ nwere ohere iji gbaa ntụtụ awa atọ tupu mgbe ahụ ma ọ bụ awa 3 gachara karịa ka enyere ya.
Nke a na-enye onye ọrịa ahụ oge 6 awa nke ọ ga-emerịrị insulin basal, na-atụghị ụjọ mmụba nke shuga ọbara. Ngwongwo ọgwụ a na - eme ka ndụ onye ọrịa mamịrị na - eme ka ndụ ya ghara ịdị, n'ihi na ọ na - enye ya ohere ịme inje na gburugburu ebe kachasị adaba.
Ntughari nke uzo ogwu a gha agha kwa n’otu n’otu na ntinye aka nke endocrinologist. Oru ubara insulin guzobere n’enwe mgbanwe nke mmanye n’onye mgbanwe n’ariri ahu ike nke onye oria, bughari n’iri nri ozo, bulie ma obu iwetulata ahu aru, ma gbanwee oge ngbanye ya.
Mgbe ị na-eji insulin basal eme ihe, Tujeo ga-atụrịrị shuga ọbara ugboro abụọ n'ụbọchị. Oge kachasị mma maka nke a bụ ụtụtụ na mgbede. Ọ dị mkpa imesi ya ike na ọgwụ Tujeo adaghị maka ọgwụgwọ nke ketoacidosis. Ekwesịrị iji insulins dị mkpụmkpụ maka ebumnuche a.
Ofzọ ọgwụgwọ Tujeo si dabere na ụdị ọrịa shuga na-arịa onye ọrịa:
- Tujeo nwere oria 1. Ọgwụ ọgwụgwọ maka ọrịa a kwesịrị ijikọ insulin insulin na-arụ ọrụ ogologo oge na iji insulin insulin dị mkpirikpi. N'okwu a, ekwesịrị ịhọrọ ọgwụ insulin Tuje kpamkpam ka ewere ya.
- Tujeo nwere ọrịa shuga nke 2. N'ime ụdị ọrịa shuga a, endocrinologists na-adụ ndị ọrịa ha aka ịhọrọ ụzọ ziri ezi nke ọgwụ ahụ dabere n'eziokwu ahụ maka kilogram nke ọ bụla onye ọrịa chọrọ 0.2 nkeji / ml. Tinye insulin basal otu ugboro n'ụbọchị, ọ bụrụ na ọ dị mkpa, na-edozi dose ahụ n'otu uzo ma ọ bụ ọzọ.
Ọtụtụ ndị ọrịa nwere ọrịa shuga amaghị etu esi agbanwe site na iji Lantus gaa Tujeo. N'agbanyeghị eziokwu ahụ bụ na ọgwụ abụọ ahụ sitere na glargine, ha abụghị bioequurate ya mere na-atụleghị ka ha na-agbanwe agbanwe.
Na mbu, a na-adụ onye ọrịa ọdụ ka ọ were nyefe ọgwụ were otu insulin mee ihe na nke ọzọ na ọnụego otu. Agbanyeghị, n’ụbọchị mbụ eji Tujeo eme ihe, onye ọrịa kwesịrị iji nlezianya nyochaa ọkwa nke glucose dị n’ahụ. O kwere omume na iji mezuo ọkwa shuga dị ọbara a chọrọ, onye ọrịa ga-achọ ịbawanye ọgwụ a.
Ntughari site na insulins ndị ọzọ na ọgwụ Tujeo chọrọ nkwadebe siri ike karị, ebe ọ bụ na nke a, a ga-agbanwe usoro ọgwụgwọ ọ bụghị naanị maka insulins ogologo oge, kamakwa maka ndị na-eme obere oge. Maka ndị ọrịa nwere ụdị shuga 2, a ga-agbanwekwa usoro nke ndị na - ahụ ihe hypoglycemic.
- Ntughari site na insulin eme ihe ruo ogologo oge. N'ọnọdụ a, onye ọrịa nwere ike ọ gaghị agbanwe usoro onunu ogwu ya, na-ahapụrụ ya otu ihe ahụ. Ọ bụrụ n’ọdịniihu onye ọrịa ahụ na-achọpụta mmụba shuga ma ọ bụ, n’ụzọ megidere, mgbaàmà nke hypoglycemia, a ga-agbaziri dose ahụ.
- Ntughari site na insulins ndị na-ajụ ase. A na-etinye insulins medal na-eme n'ime ahụ onye ọrịa ugboro abụọ n'ụbọchị, nke bụ ọdịiche ha dị ukwuu site na Tujeo. Iji gbakọọ izu nke ọgwụ ọhụụ, ọ dị mkpa ichikota dum olu nke insal insulin kwa ụbọchị ma wepụ ya ihe dịka 20%. 80% fọdụrụnụ ga-abụ usoro ọgwụgwọ kwesịrị ekwesị maka insulin ogologo oge.
Ekwesiri ime ka ọ pụta ìhè na ọgwụ Tujeo machibidoro ịgwakọta na insulins ndị ọzọ ma ọ bụ gwakọta ya na ihe ọ bụla, n'ihi na nke a nwere ike ime ka ọ dị mkpụmkpụ ma kpatara ọdịda.
Ofzọ nke ngwa
Toujeo ezubere naanị maka itinye ya n'ime anụ dị n'okpuru afọ, apata ụkwụ na ogwe aka. Ọ dị mkpa ịgbanwe saịtị ịgba ntụtụ kwa ụbọchị iji gbochie ịmalite nke scars na mmepe nke hyper- ma ọ bụ hypotrophy nke anụ ahụ dị n'okpuru ala.
Ekwesịrị izere iwebata insulin basal Tuino na akwara, n'ihi na nke a nwere ike ibute nnukwu hypoglycemia. Ogologo oge ọgwụ a na-adịgide naanị na ọgwụ ntụtụ. Na mgbakwunye, ọgwụ Tujeo enweghị ike iji ọgwụ insulin gbanye n'ahụ mmadụ.
N'iji pen-syringe mee ihe, onye ọrịa ahụ ga-enwe ike ibunye onwe ya site na iji nkeji 1 ruo 80. Na mgbakwunye, n'oge eji ya, onye ọrịa ahụ nwere ohere ịbawanye ọgwụ insulin site na otu 1 n'otu oge.
Iwu maka mkpụrụ edemede sirinji:
- E dere mkpụrụ akwụkwọ sirinji ka ọ nwee mita onunu ogwu nke na-egosi onye ọrịa ahụ ọnụọgụ insulin ga-abanye n'oge ịgba ya. Emepụtara mkpịsị sirinji a ka ọ bụrụ insulin Tujeo insulin, yabụ, mgbe ị na-eji ya, ọ dịghị mkpa ịme usoro ịkọwa ọzọ,
- Ọ bụụrụ ezigbo nkụda mmụọ ka o jiri sirinji otịnye wee nweta ihe Tujeo tinye na ya. N'iji sirinji mee ihe, onye ọrịa agaghị enwe ike ikpebi usoro insulin dị n'ụzọ ziri ezi, nke nwere ike ibute nnukwu hypoglycemia.
- A machibidoro ya iwu iji otu agịga ahụ ugboro abụọ Mgbe ị na-akwadebe ọgwụ ntụtụ insulin, onye ọrịa ahụ ga-eji ọgwụ ọhụrụ dochie ochie agịga ahụ. Mkpịsị insulin dị gịrịgịrị, yabụ mgbe ị na-eji ha eme ihe, ihe egwu nke ịchipu agịga dị oke. N'okwu a, onye ọrịa ahụ nwere ike ịnata obere insulin nke ukwuu. Na mgbakwunye, iwere agịga nwere ike ibute ọrịa nke ọnya site na ntụtụ.
Ọ bụ naanị otu onye ọrịa chọrọ iji ya sụọ mkpụrụ. Ojiji ọtụtụ ndị ọrịa were otu mgbe mee ka ọ bute ọrịa na-efe efe na-ebute site n'ọbara.
Mgbe ịgba mbụ ahụ gasịrị, onye ọrịa ahụ nwere ike iji mkpịsị mkpụrụ Tujeo sisi mee ihe maka izu anọ ọzọ. Ọ dị mkpa ịchekwa ya mgbe niile na ebe gbara ọchịchịrị, ebe nchekwa anyanwụ na-echebe ya nke ọma.
Ka ị ghara ichefu ụbọchị nke ntụtụ mbụ ahụ, a ga-egosipụta ya n'ahụ nke mkpụrụ sirinji.
Ekwenyere insulin toulino basal n'oge na-adịbeghị anya na Russia na July 2016. Ya mere, ọ natabeghị ụdị nkesa sara mbara n'obodo anyị dịka ndị nnwale ndị ọzọ na-eme ogologo oge.
Ọnụ ego dị elu nke Tujeo na Russia bụ ihe dịka 3,000 rubles. Nke kacha nta dị ihe dịka 2800 rubles, ebe kacha nwere ike iru ihe ruru 3200 rubles.
Enwere ike ịtụle insulin ndị ọzọ nke ọgbọ ọhụrụ dịka analogues nke ọgwụ Tujeo. Otu n'ime ọgwụ ndị a bụ Tresiba, nke e mepụtara na insulin Degludec insulin. Degludek nwere ngwongwo yiri ya na Glargin 300.
Ọzọkwa, a na-enwe mmetụta yiri nke ahụ n'ahụ onye ọrịa ahụ site na insulin peglizpro, na-adabere na ya nke a na-emepụta ọtụtụ ọgwụ maka ndị ọrịa shuga taa. Vidio dị na isiokwu a ga - enyere gị aka ịchọpụta mgbe edepụtara insulin.
Ojiji na Usoro Ọgwụ
Tujeo Solostar na-arụ naanị subcutaneously, na ubu, afọ ma ọ bụ apata ụkwụ. Ekwesịrị ịgbanye ebe ndị irighiri oge niile (iji gbochie mmeghachi omume na-adịghị mma). Ezubeghi ọgwụ ahụ maka nchịkwa na nchịkwa ọbara site na nfuli insulin. Dabere na usoro ọgwụ a na-ahụ maka ọgwụ nke ndị dibịa na-ekwu okwu, sitere na nkeji 1 ruo 80 na-eji mkpịsị mkpụrụ sitere.
Emebe Solostar ka ewepụ ya na katriiki wee kwaga na sirinji. Amachibidoro iji agịga a ugboro ugboro, ebe enwere ike igbochi ya, n'ihi mmụba ma ọ bụ ibelata usoro ọgwụ. Debe Tujeo Solostar ma ọ bụ insulin glargine n'ime ebe gbara ọchịchịrị maka ihe na-erughị izu anọ site na ojiji mbụ.
A machibidoro insulin nke Toujeo ịgwakọta ụdị insulin ọ bụla. Nke a na-eme ka mgbanwe nke akụrụngwa nke ọgwụ ahụ na-eduga ọdịda. A machibidoro Tujeo Solostar ịmụba.
Ekwesịrị ịkọwa usoro ị theụ ọgwụ ahụ wee gbanwee n'otu n'otu ma ọ bụ naanị dọkịta na-aga.
A na-agbanwe iji ogwu Tujeo mee ihe iji belata ma ọ bụ nwekwuo ahụ ike nke onye ọrịa, gbanwee ụdị ndụ ya ma ọ bụ gbanwee oge ntụtụ. A ga-ebido iwebata usoro ọgwụ a gbanwetụrụ etu ọgwụ dị n'ihu ndị ọkachamara n'ịgwọ ọrịa.
"Me ya bụ 'unit' na-ezo aka naanị insulin a, ọ bụghị otu ihe maka otu na-egosi ike nke ụzọ ndị ọzọ yiri. A ga-edozigharị Toujeo otu ugboro n'ụbọchị n'oge ọ bụla n'ụbọchị, mana ọkacha mma n'otu oge ahụ. N'ihi ogologo oge, ndị ọrịa na-enwe ike ịgbanye ọgwụ ahụ awa atọ tupu ma ọ bụ mgbe ọkọlọtọ ha zuru oke maka ha.
Debe Tujeo n'ebe gbara ọchịchịrị ma ọ bụghị karịa izu anọ site na ụbọchị mbụ ejiri!
Mgbe ịgaghị eji ya
Toujeo Solostar bụ contraindicated maka ndị nwere ọrịa shuga na-erubeghị afọ 18 n'ihi enweghị nyocha ụlọ ọgwụ na nke ọgbọ a maka nchekwa nke ọgwụ ma ọ bụ maka nnabata nke Toujeo ma ọ bụ insulin glargine.
Ekwesịrị ịkpachara anya na ịkọwapụta:
- Womenmụ nwanyị dị ime (na njikọta na ọ ga-ekwe omume dochie anya ọgwụ a na-a afterụ mgbe ha mụsịrị nwa na oge ịtụrụ ime).
- Ndị okenye (ihe karịrị afọ iri asaa).
- Na-arịa ọrịa shuga na ọnụnọ nke ọrịa endocrinological.
Mgbe ị na-atụgharị site na otu insulin gaa na nke ọzọ, ọ dị mkpa ịmalite nyocha nke ndị endocrinologists, naanị a ga-ahọrọ. N'ọnọdụ ọnya ọnya na ọgbụgbọ na ọgbụgbọ, oke akụrụ ma ọ bụ ọdịda akwara, ọ dịkwa mkpa ịkpachara anya.
Ihe ichere mgbe ewere ya na ezighi ezi
Ọ bụrụ na ọgwụ a karịrị gafere, hypoglycemia nwere ike ịdapụta (mmeghachi akachasị njọ na ọgwụgwọ insulin).
Ihe ịrịba ama nke hypoglycemia bụ:
- Adịghị Ike.
- Ike ike
- Ahụ erughị ala
- Igwe ojii
- Mmepo.
- Ọnwụ nke mmụọ.
Tupu mmalite nke ihe ịrịba ama, tachycardia, agụụ nke agụụ, ahụ erughị ala, mmetụta nke ụjọ na ụjọ nwere ike ịdapụta, ọsụsọ, pallor nke anụ ahụ.
N'ime ndị ọrịa nwere ọrịa shuga, nsogbu nwere ike ịhụ nwa oge nwere ike ịpụta. N'ebe inje nke Toujeo na insulin glargine, mmepe nke lipodystrophy, ọdịdị nke itching, urticaria, mgbu, mbufụt, na ịcha ọbara ọbara ga-ekwe omume.
Iji gbochie mmeghachi omume na-adịghị mma, a na-arụ ọrụ inje n'ebe dị iche iche.
Mmeghachi omume nfụkasị nke ngosipụta ozugbo bụ nke obere.
Omume yitere
Tujeo Solostar nwere insulin nke ukwuu. Ihe dị iche n'ihe analogue bụ na Tujeo nwere okpukpu atọ nke arụ ọrụ (ya bụ, otu ml nke otu ọgwụ Tujeo Solostar insulin na ml atọ nke analogue). N'ihi ya, mgbe ị na-agbanwe site na ọgwụ na-adịchaghị ike gaa na nke siri ike, ị ga-agakwuru dọkịta gị, onye ga-ekpebi elekere ole insulin iji belata site na ọgwụ ole ị na-enye.
Mgbe ị na-agbanye insulin, Tujeo Solostar ga-agakwuru dọkịta mgbe niile!
N'oge ọnwụnwa nke ụlọ ọgwụ, onye rụpụtara ekpughere na mmiri nke Toujeo ga-agbasafefe ahụ karịa, nke a na-ebelata ike nke hypoglycemia, ọkachasị n'abalị. N'iji ya tụnyere ndị ọgbọ, Tujeo Solostar ruru pasenti iri na ise na ehihie na pasent 30 n'ime abalị na-ebelata ọghọm hypoglycemia, ebe Solostar nwere ezigbo akara ure.
Ihe anakpo Toujeo ana ahazi ogo glucose di n’ahu n’ime ubochi niile, mana n’omume ya ka o di obere ihe kariri iri n’abuo
Nkezi ego insulin Tujeo Solostar bu 3000 rubles.
Ọnụ ego nke insulin lantus bụ 3550 rubles (mkpụrụ sirinji 100 IU / ml 3 ml, 5 PC.)
Ọ bụrụ na ịchọrọ ị insụ insulin, ndị ọrịa kwesịrị inwe ike ịchịkwa ọkwa nke glucose n'ọbara, nwee usoro ọgwụgwọ kwesịrị ekwesị, marakwa ihe ị ga-eme mgbe hyper - na hypoglycemia pụta. N’ọnọdụ ọ bụla ị ga-edozighị onwe gị oge usoro ịgba ọgwụ nke dọkịta depụtara na ego insulin gbanyere n’ọrụ, agbanyela na ọgwụ insulin ọzọ (ejila blog ọgwụ na ịntanetị kama ịbụ ezigbo dọkịta), wee chọọ ndụmọdụ ahụike ozugbo.
Toujeo Solostar ga-abụ onye enyemaka a pụrụ ịdabere na ya maka ndị nwere ọrịa shuga. Ndị ọrụ Sanofi nyere Tujeo ọrụ ogologo oge, nke na-enye ohere injections naanị otu ugboro kwa ụbọchị, ihe ndị mejupụtara ya na-ebelata nnukwu nsogbu nke hypoglycemia.
Uru na ọghọm ya
Uru nke Tujeo ma e jiri ya tụnyere ọgwụ ndị yiri ya gụnyere:
- ogologo oge nke ihe karịrị ụbọchị 2,
- ihe ize ndụ nke ịmalite ịrịa hypoglycemia n'abalị n'abalị,
- obere onunu ogwu na, ya mere, obere oriri nke ọgwụ iji nweta mmetụta chọrọ.
- pere mpe mmetụta
- ihe nkwụghachi ụgwọ dị elu
- Ikike ibu dị ntakịrị na iji ya mgbe niile
- ezigbo ihe na-enweghị spikes na shuga.
Otu n'ime adịghị ike nwere ike mata:
- enyela umuaka iwu
- ejighị ya na ọgwụgwọ nke ọrịa ketoacidosis mamịrị,
- ewepu ihe oghom n’agha.
Ihe ngosi na contraindications
Ihe ngosi maka ojiji:
- Ọrịa shuga 1 na insulin,
- T2DM dị ka monotherapy ma ọ bụ ọgwụ mgbochi antidiabetic nke ọnụ.
A naghị akwado Tujeo maka ọnọdụ ndị a: hypersensitivity nke homonụ ma ọ bụ ihe mejupụtara ọgwụ ahụ, n'okpuru afọ 18, n'ihi enweghị nchekwa nchekwa.
Ekwesịrị iji nlezianya mesịa ìgwè ndị ọrịa a:
- ọnụnọ nke ọrịa endocrine,
- ndị agadi nwere ọrịa akụrụ,
- n'ihu ọnụnọ nke imeju.
N'ime ndị otu a, mkpa maka homonụ nwere ike dị ala n'ihi na ọ na-ebelata ike ha.
Dị Mkpa! N'ime usoro nyocha, enweghị mmetụta akọwapụtara na nwa ebu n'afọ. Enwere ike ịkọ ọgwụ a n'oge afọ ime, ma ọ bụrụ na ọ dị mkpa.
Ọrịa na-eji ọgwụ ahụ eme ihe n’agbanyeghi oge nri. A na-atụ aro ịgbanye ya n’otu oge. A na-enye ya subcutaneously otu ugboro n'ụbọchị. Ntachi obi bụ awa 3.
A na-ekpebi usoro ịlogistụ ọgwụ ahụ site na endocrinologist dabere na akụkọ ahụike - afọ, ogo, ịdị arọ nke onye ọrịa, a na-elebara ụdị ọrịa ahụ anya.
Mgbe ị na-edochi homonụ ma ọ bụ na-agbanwe na akara ọzọ, ọ dị mkpa ijikwa ọkwa glucose ike.
N'ime otu ọnwa, a na-enyocha ndị na-egosi metabolic. Na ntughari, ịnwere ike ịbelata 20% iji gbochie mbelata nke glucose ọbara.
Mara! A naghị akụ Tujeo ma ọ bụ gwakọta ya na ọgwụ ndị ọzọ. Nke a mebiri profaịlụ omume nwa oge ya.
Dose ukpụhọde bụ ndị a ikpe:
- mgbanwe nri
- ngbanwe na ogwu ozo
- Ọrịa ma ọ bụ nke oria dị adị
- mgbanwe nke mmega ahụ.
Ofzọ nchịkwa
A na-eji Tujeo arụ ọrụ naanị subcutaneously na mkpịsị mkpụrụ sirinji. Mpaghara a na-atụ aro - mgbidi akụkụ ihu, apata ụkwụ, akwara ubu elu. Iji gbochie ịmepụta ọnya, a gbanwere ebe injections na-enweghị otu mpaghara. Amachibidoro iji ọgwụ ahụ site na enyemaka nke nfuli ọkpọkọ.
Ndị ọrịa nwere ụdị oria 1 na-ewere Tujeo na usoro ọgwụgwọ nke ya yana insulin dị mkpụmkpụ. A na-enye ndị ọrịa nwere ụdị ọrịa shuga 2 ọgwụ dị ka monotherapy ma ọ bụ na mbadamba ụrọ na ọkara nke 0.2 nkeji / n'arọ nwere mmezi enwere ike.
Ntị! Tupu nchịkwa, ekwesịrị ịdebe ọgwụ ahụ na ụlọ okpomọkụ.
Nkuzi vidiyo na iji sirinji:
Mmeghari Ahụhụ yana dofịkasị
Nsonaazụ kachasị emetụta bụ hypoglycemia. Ihe omumu ihe banyere ulo ogwu achoputala mmeghachi omume ojoo ndia.
Na usoro ị ga-ewere Tujeo, nsonaazụ ndị a na - esote nwere ike ime:
- mmebi anya
- lipohypertrophy na lipoatrophy,
- mmeghachi omume nfụkasị ahụ
- mmeghachi omume mpaghara na mpaghara irighiri - itching, swelling, redness.
Dodoụbiga mmanya ókè na-abụkarị mgbe usoro ọgwụgwọ homonụ nke ọgwụ batara karịrị ihe achọrọ maka ya. Ọ nwere ike ịdị nfe ma sie ike, mgbe ụfọdụ ọ na-ebute onye ọrịa nnukwu ihe egwu.
Site na ịdoụbiga mmanya ókè, a na-edozi hypoglycemia site na ị carbohydụ carbohydrates ma ọ bụ glucose. N'ihe omume ndị dị otú a, idozi usoro ọgwụ ga-ekwe omume.
N'ọnọdụ ndị siri ike, nke a na-esochi ọnwụ nke akọ, coma, ọgwụ chọrọ. A na-etinye onye ọrịa ahụ glucose ma ọ bụ glucagon.
Ogologo oge, a na-enyocha ọnọdụ ahụ iji zere akụkọ ugboro ugboro.
A na-echekwa ọgwụ a site na t + site na + 2 ruo +9.
Ntị! Amachibidoro iji ifriizi!
Ọnụahịa nke ihe ngwọta Tujeo bụ 300 nkeji / milimita, mkpịsị mkpụrụ nke mpekere 1.5, pcs 5. - 2800 rubles.
Analogues nke ọgwụ gụnyere ọgwụ nwere otu ihe eji arụ ọrụ (insulin Glargin) - Aylar, Lantus Optiset, Lantus Solostar.
Iji ọgwụ ọjọọ eme ihe nwere otu ụdị ọrụ, ma ihe ndị ọzọ na - arụ ọrụ (insulin Detemir) gụnyere Levemir Penfil na Levemir Flekspen.
Relelị site na ndenye ọgwụ.
Echiche onye ọrịa
Site na nyocha ndị ọrịa banyere Tujeo Solostar, anyị nwere ike ikwubi na ọgwụ ahụ adabaraghị onye ọ bụla. Onweghi oke oke nke ndị ọrịa mamịrị enweghị afọ ojuju ọgwụ na ike belata shuga ọbara. Ndị ọzọ, n'ụzọ megidere, na-ekwu maka omume ya dị mma na enweghị nzaghachi.
Akwukwo ndi ozo ndi ozo choro
Tujeo Solostar: ọnụahịa dị na ahịa ọgwụ na ntụle ọnụahịa, ọchụchọ na ịtụ
Gosi na maapụ
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 1 | 940,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 1 | 1 059,60 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 1 | 1 096,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 060,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 128,00 | 24 ikp |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 217,00 | 24 ikp |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 277,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 281,50 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 318,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 398,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 450,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 450,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 450,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 450,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 3 | 3 475,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 4 700,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 4 728,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 200,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 268,00 | 24 ikp |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 369,00 | 24 ikp |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 372,10 | 24 ikp |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 384,90 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 600,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 600,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 670,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 5 670,00 | |
katriki 300ME / ml 1.5ml sirinji SoloStar Nke 5 | 6 090,00 | 24 ikp |
Tujeo SoloStar gbakwunyere mgbako mgbako insulin Dosem Algorithm - Ihe Nlereanya Dị Iche
Nke mbu, onye ikwu gi nwere ụgwọ nkwụghi ụgwọ maka shuga ọbara, n'ihi site na 7 ruo 11 mmol / l - ndị a bụ nnukwu shuga, enweghị atụ na-eduga n'ọrịa mamịrị. Ya mere, nhọrọ nke usoro ọgwụ insulin chọrọ ka ọ dị chọrọ. Did deghị ụbọchị ole o nwere shuga 5 mmol / l, yana oge ọ rutere 10-11 mmol / l?
Basal Insulin Tujeo SoloStar (Toujeo)
Toujeo SoloStar (Toujeo) nwere insulin gbatịrị - ọkwa ọhụrụ nke ụlọ ọrụ ọgwụ Sanofi, nke na-emepụta Lantus. Ogologo oge nke ihe ọ na-eme dị ogologo karịa nke Lantus - ọ na-adịgide> awa 24 (ruo awa 35) ma e jiri ya tụnyere awa 24 nke Lantus.
Insulin Tozheo SoloStar Odi ihe nlere kariri Lantus (nari ato / milu iri n’otu nari 100 / ml maka Lantus). Mana ntuziaka maka ojiji a na-ekwu na ọgwụ ahụ ga-abụrịrị nke Lantus, otu na otu. Ọ bụ naanị na itinye uche nke insulins ndị a dị iche, mana gradation na nkeji itinye ihe na-adịgide.
Na-ekpe ikpe site na nyocha nke ndị ọrịa mamịrị, Tujeo na-eme ihe nzuzu na obere ike karịa Lantus, ma ọ bụrụ na itinye ya otu usoro. Biko mara na o were ụbọchị 3-5 ka Tujeo rụọ ọrụ zuru oke (nke a metụtakwara Lantus - ọ na-ewe oge iji kwado insulin ọhụụ). Ya mere, nwalee, ọ bụrụ na ọ dị mkpa, belata usoro ya.
Enwekwara m ụdị shuga 1, ana m eji Levemir ka insulin basal. Enwere m otu usoro onunu ogwu - etinye m nkeji iri na anọ n’etiti ehihie na elekere 15 ruo 15 ruo 15.
Ihe algorithm maka ịgbakọ dose insulin Tujeo SoloStar (Levemira, Lantus)
Ikwesiri ka gị na onye ikwu gị nọrọ ngụkọta oge ịchọrọ ị ofụ insulin. Emere nke a dika ndi a:
- Ka anyị bido site n’ịgụkọ mgbede. Mee ka onye ikwu gị rie nri dị ka ị na-eribu ma gharakwa iri ụbọchị ahụ. Nke a dị mkpa iji wepu nsị shuga nke na-eri site na iri nri na insulin obere. Ebe site na 18-00 na-amalite mgbe ọ bụla awa 1.5 na-ewere shuga ọbara ya. Enweghị nri abalị. Ọ bụrụ na ọ dị mkpa, tinye obere insulin dị mfe iji mee ka ọkwa shuga dị nkịtị.
- N'elekere 22 ka itinye insulin na-emebu. Mgbe ị na-eji Toujeo SoloStar 300, ana m akwado ịmalite na nkeji iri na ise. 2 awa mgbe ogwu ogbugba, bido ilekwa nha shuga ọbara. Debe akwukwo ihe edere - dekọ oge ntụtụ na ihe ngosipụta nke glycemia. Enwere ihe ize ndụ nke hypoglycemia, yabụ ịkwesịrị idobe ihe dị ụtọ na aka - tii na-ekpo ọkụ, ihe ọ sweetụ sweetụ dị ụtọ, cubes, mbadamba Dextro4, wdg.
- Peul basal insulin kwesịrị ị bia n'ihe dị ka elekere 2-4 nke ụtụtụ, yabụ nọrọ na nche. Enwere ike ịme nha shuga kwa awa.
- Ya mere, ị nwere ike soro arụmọrụ nke mgbede (abalị) nke insulin agbatị. Ọ bụrụ na shuga na-ebelata n'abalị, mgbe ahụ, a ga-belata dose ahụ site na otu 1 wee gaa n'ọmụmụ ihe ahụ ọzọ. Ọzọ, ọ bụrụ na shuga na-eto, mgbe ahụ usoro onunu ogwu nke Toujeo SoloStar 300 kwesịrị iwelie ntakịrị.
- N'otu aka ahụ, nwalee dose ụtụtụ nke basal insulin. Ọ ka mma ọ bụghị ozugbo - buru ụzọ mee ihe banyere mgbede, mezie usoro kwa ụbọchị.
Mgbe ị na-agbakọ ọ̀tụ̀tụ̀ insulin insulin kwa awa 1-1.5, tụọ shuga ọbara
Dịka ọmụmaatụ, aga m enye akwụkwọ edetu m maka ịhọrọ ntụtụ nke insulin Levemir (iji ọgwụ ụtụtụ dị ka ihe atụ):
Na elekere asaa ka ọ setịpụrụ nkeji iri na anọ nke Levemir.Eat riri nri ụtụtụ.
oge | ọbara shuga |
7-00 | 4.5 mmol / l |
10-00 | 5,1 mmol / l |
12-00 | 5,8 mmol / L |
13-00 | 5,2 mmol / l |
14-00 | 6,0 mmol / l |
15-00 | 5,5 mmol / l |
Site na tebụl enwere ike ịhụ na eburu m ọgwụ ziri ezi nke ụtụtụ ogologo oge ụtụtụ, n'ihi shuga nọ na ya. Ọ bụrụ na ha malitere ịba ụba site n’ihe dị ka awa iri na abụọ na 10-12, mgbe ahụ, nke a ga-abụ ihe mgbaàmà ịbawanye ọnya. Na Anglịkan.
Insulin Tujeo Solostar: ntuziaka maka onye dabara, ọnụahịa
Ọnụ ọgụgụ ndị ọrịa na-arịa ọrịa shuga na Russia karịrị nde 6, ọkara n'ime ha nwere ọrịa ahụ na nkewa. Iji meziwanye ndụ nke ndị ọrịa mamịrị, mmepe nke insulins ka mma na-aga n'ihu.
Otu n'ime ọgwụ ọhụụ edepụtara aha na afọ ndị na-adịbeghị anya bụ Toujeo. Nke a bụ insulin basal ọhụrụ, nke a na-ahụ maka otu ugboro kwa ụbọchị ma na-enye gị ohere ịmezi njikwa glycemic ma ọ bụrụ na e buru ya ụzọ, Lantus. Dabere na ọmụmụ, Tujeo dị mma maka ndị ọrịa, ebe ọ bụ na ihe ize ndụ nke hypoglycemia na ojiji ya dị ala.
Ntụziaka dị mkpirikpi
Tujeo SoloStar bụ ngwaahịa nke otu n'ime ndị isi ụwa na mmepụta insulin, ihe ndị European na-emetụta Sanofi. Na Russia, ngwaahịa ụlọ ọrụ ahụ anọchi anya ihe karịrị afọ iri anọ. Tujeo nwetara akwụkwọ ndebanye aha ndị Russia na nso nso a, n’afọ 2016. Na 2018, a malitere imepụta insulin a n'alaka Sanofi-Aventis Vostok, nke dị na mpaghara Oryol.
Ndewo Aha m bụ Galina, enweghịzi m ọrịa shuga! O were m naanị izu 3Ighaghachi shuga n’agha ma ghara iji ọgwụ ọjọọ na-enweghị ihe ọ bụla riri ya ahụ
>> Can nwere ike gụọ akụkọ m ebe a.
Onye rụpụtara ya tụrụ aro ka ịgbanye insulin Tujeo ma ọ bụrụ na ọ gaghị ekwe omume ịkwụ ụgwọ zuru oke maka ọrịa shuga ma ọ bụ wepu hypoglycemia ugboro ugboro. Ọtụtụ ndị ọrịa mamịrị ga-eji Tujeo n'agbanyeghị agbụrụ ha chọrọ, dịka akụkụ nke mpaghara Russia zụrụ insulin kama nke Lantus.
Mpempe mwepụta | Toujeo nwere okpukpu atọ dị elu karịa ka ọ na-emebu insulin na-emebu - U300. Azịza ya bụ ụzọ doro anya, ọ naghị achọ agwakọta tupu nchịkwa. A na-etinye insulin n'ime katriiki iko nke milimita 1.5, nke a na-akachasị akara na sịnịma SoloStar nwere usoro usoro 1 ml. Anaghị enye dochie katriji n'ime ha, mgbe ejiri ha sichara ya. Na ngwugwu 3 ma ọ bụ 5 mkpịsị sirinji. |
Ntụziaka pụrụ iche | Fọdụ ndị ọrịa mamịrị na-esi pensọl sirinji naanị iji rụọ ọrụ n'ime ntụtụ ngwaọrụ iji tinye ha ntụtụ ọgwụ nke ọma. Mgbe ị na-eji Tujeo eme ya machibidoro kpam kpam, ebe ọ bụ na akụrụngwa sirinji niile, ewezuga SoloStar mbụ, emere maka insulin U100. Dochie ngwaọrụ nchịkwa nwere ike ibute ple overụbiga ọgwụ ike okpukpu atọ. |
Ngwakọta | Dị ka ọ dị na Lantus, ihe na-arụ ọrụ bụ glargine, yabụ ụkpụrụ nke ọrụ insulins ndị a bụ otu. Ndepụta nke ihe inyeaka jikọtara ọnụ kpamkpam: m-cresol, glycerin, chloride zinc, mmiri, ihe dị iche iche maka ndozi nke acidity. N'ihi otu ihe mejupụtara, a na-ebelata ihe ize ndụ nke mmeghachi omume nfụkasị n'oge mgbanwe site n'otu insulin gaa na nke ọzọ ruo efu. Ọnụnọ nke nchekwa abụọ na ngwọta ahụ na-enye ohere ịchekwa ọgwụ ahụ ogologo oge, na-elekọta ya na-enweghị ọgwụgwọ ọgwụ mgbochi ọzọ nke anụ ahụ, na-ebelata ihe ize ndụ nke mbufụt ahụ na ntụtụ. |
Omume ọgwụ | Yiri nke insulin emekọtara n'ime ahụ ike. N'agbanyeghi obere ihe di iche na nhazi nke glargine na insulin endogenous, Tujeo nwekwara ike kegide ndi na - anabata insulin, na - eme ka glucose si n’ọbara banye n’arụ. N'otu oge ahụ, ọ na-akpali nchekwa nke glycogen na akwara na umeji (glycogenogenesis), na-egbochi nguzobe site na imeju (gluconeogenesis), na-egbochi imebi abụba, ma na-akwado guzobe protein. |
Ihe na-egosi | Ntughari onughari insulin n’ime ndi okenye nwere oria shuga. A kwadoro insulin Tujeo maka ndị ọrịa nwere ọrịa nephropathy na-arịa ọrịa mamịrị, ọdịda akụrụ, na ọrịa imeju. Dịka iwu, usoro ya na ihe ndị a dị ntakịrị. |
Usoro onunu ogwu | Ntụziaka maka iji ya eme ihe anaghị enwe usoro Tujeo tụrụ aro, ebe ọ bụ na ahọpụtara ọgwụ insulin kwesịrị ịhọrọ ya n'otu n'otu dabere na shuga dị n'ọbara. Mgbe ha na-agbakọ insulin, ihe na-eduzi ha bụ data nke ọ bụla n'ehihie glycemia. Onye rụpụtara ya tụrụ aro ka ịgbanye Tujeo otu ugboro n'ụbọchị. Ọ bụrụ n’otu ịgba ọgwụ mgbochi anaghị ekwe ka imepụta shuga dị mma n’afọ na-enweghị isi, a ga-ekewa ụbọchị ahụ ụzọ abụọ. Mgbe nke ahụ gasịrị, a na-enye ọgwụ mgbochi tupu ụra, nke abụọ n'isi ụtụtụ. |
Dodoụbiga ya ókè | Ọ bụrụ na ego nke Tujeo na-achị gafere mkpa insulin nke onye ọrịa, a ga-agharịrị ịrịa hypoglycemia. Na ogbo nke mbụ, a na-ejikọkarị ya na mgbaàmà doro anya - agụụ, ịma jijiji, obi. Ma onye na-arịa ọrịa shuga na ndị ikwu ya kwesịrị ịma iwu nke ụgbọ ihe mberede maka hypoglycemia, na-ebu carbohydrates ngwa ngwa yana otu enyemaka nke glucagon. |
Mmetụta nke ihe ndị dị na mpụga | Insulin bu homonụ nke nwere ike ịda mba ọzọ homonụ nke arụ n’arụ mmadụ, ndị akpọrọ antagonist. Ọkpụkpọ anụ ahụ nye ọgwụ nwere ike ibelata ruo nwa oge. Mgbanwe ndị a bụ njiri mara ọnọdụ ndị so n'ọbara endocrine, ahụ ọkụ, ọgbụgbọ, afọ ọsịsa, oke ọnya afọ, na nchekasị. N'ime ndị ahụ dị mma, n'oge oge ndị a, mmụpụta nke insulin na-abawanye, ndị ọrịa mamịrị kwesịrị ịbawanye dose nke Tujeo. |
Ihe ngbanwe | Dochie ọgwụ a dị mkpa ma ọ bụrụ na enwere mmeghachi omume nfụkasị glargine ma ọ bụ ihe inyeaka. Tujeo, dị ka insulin ọ bụla toro ogologo, enweghị ike iji ya mee ihe maka ndozi ọbara shuga. Ọrụ ya bụ ịnọgide na-enwe glycemia n'otu ọkwa ahụ .. N'ihi enweghị ọmụmụ na-egosi na nchekwa nke ụmụaka, insịnye Tujeo kwere naanị maka ndị ọrịa mamịrị. |
Mmekọrịta na ọgwụ ndị ọzọ | Hormonal, antihypertensive, psychotropic, ụfọdụ ọgwụ nje na ọgwụ mgbochi mkparị nwere ike imetụta mmetụta hypoglycemic. Ọgwụ gị niile ejiri ọgwụ shuga kwenye na dọkịta gị. |
Mmetụta akụkụ | Dịka ntuziaka ahụ si dị, ndị ọrịa mamịrị nwere ike inweta:
Mbelata shuga dị mma mgbe mmalite insulin na-agwọ ọrịa nwere ike ibute neuropathy nwa oge, myalgia, ọhụụ mara mma, ọzịza. Nsonaazụ ndị a ga-apụ n’anya mgbe imegharị ahụ. Iji zere ha, ndị ọrịa nwere ọrịa mellitus na-arịa ọrịa shuga na-amụba nke Tujeo SoloStar nke nta nke nta, na-enweta mgbada nwayọọ nwayọọ na glycemia. |
Ime | Insulin Tujeo anaghị akpata nsogbu mmepe nwa ebu n'afọ; ọ bụrụ na ọ dị mkpa, enwere ike iji ya n'oge ime. Ọ fọrọ nke nta ka ọ ghara ịbanye na mmiri ara ehi, ya mere a na-ahapụ ụmụ nwanyị inye nwa ara na ọgwụgwọ insulin. |
Jiri na umuaka | Ruo ugbu a, ntuziaka maka Tujeo machibidoro iji insulin a n'ahụ ụmụaka nwere ọrịa shuga. Echere na dịka nsonaazụ nke nyocha pụtara, a ga-ewepụ mmachi a. |
Exbọchị mmebi | Afọ 2,5 site n’ụbọchị e nyere ya, izu anọ ka emepere katriiki, ọ bụrụ na ezutara ọnọdụ nchekwa. |
Njirimara nke nchekwa na njem | A na-echekwa Tujeo SoloStar na 2-8 Celsius C na friji, mkpịsị sirinji ejiri mee bụ n'ime ma ọ bụrụ na okpomọkụ dị n'ime ya anaghị akarị 30 Celsius. Insulin na-efunari ihe omuma ya mgbe ekpughere ya n’agha site n’itughari ahihia, ntu oyi, kpo oku karie ya, yabụ mkpuchi oku pụrụ iche na-echebe ya n’oge njem. |
Ọnụahịa | Otu ngwugwu nwere pensụl pensụ atọ (mkpokọta 1350) na-efu ihe dịka 3200 rubles. Ọnụahịa nke igbe nwere aka 5 (nkeji 2250) bụ 5200 rubles. |
Ozi bara uru banyere Tujeo
Toujeo bụ insulin kachasị ogologo na ndị otu ya. Ugbu a, ọ karịrị naanị ọgwụ Tresib, nke metụtara insulins ndị nwere ogologo oge. Tujeo ji nwayọ banye n’ime arịa ahụ n’ọkpụkpụ ọkpọ ma n’ime awa iri abụọ na anọ na-enye glycemia kwụsiri ike, mgbe nke a gasịrị nsonaazụ ya ji nwayọ nwayọ. Oge awa ọrụ bụ ihe dịka awa iri atọ na isii.
Dị ka insulins ndị ọzọ, Tujeo enweghị ike dochie mmepụta homonụ nke eke ahụ kpamkpam. Na agbanyeghị, nsonaazụ ya dịkwa nso maka mkpa anụ ahụ. Ọgwụ nwere ihe fọrọ nke nta ka ọ bụrụ ihe na - eme ka ụbọchị dị, nke na - eme ka nhọrọ ịhọrọ ya belata, belata ọnụọgụ na ogo nke hypoglycemia, ma nwee ọfụma maka ọrịa mellitus na agadi.
A na-atụ aro insulin Tujeo karịsịa maka ndị ọrịa nwere nnukwu ọgwụ ọgwụ. A na - eji obere mkpịsị ọdee gbanyere mkpịsị sirinji belata ugboro atọ, yabụ, belata mbibi nke anụ ahụ, a na-anabatacha injezo ndị dị mfe.
Ọ dị ezigbo mkpa: Kwụsị ị mafụ ọgwụ mafia. Endocrinologists na-eme ka anyị na-emefu ego na pill mgbe enweghi ike imeghari shuga ọbara maka naanị 143 rubles ... >> >> gụọ akụkọ akụkọ Andrey Smolyar
Ndịiche si na Lantus
Onye rụpụtara ekpughere ọtụtụ uru nke Tujeo SoloStar karịa Lantus, yabụ, na ezughi ụgwọ maka ọrịa shuga, ọ na-atụ aro ka ịgbanye ọgwụ ọhụrụ.
>> Gụkwuo gbasara insulin Lantus - gụọ ebe a
Uru insulin Tujeo:
- Olu a ga-eme dị pere mpe, yabụ mpaghara a na-akpọtụrụ ọgwụ ọgwụ na arịa ọbara, homonụ na-abanye nwayọ nwayọ.
- Oge a na-eme ihe karịrị awa iri abụọ na anọ, nke na-enye gị ohere ịgbanye oge oge injection n’emebighị ahụike.
- Mgbe ị na-agbanye na Toujeo site na insulin basal ndị ọzọ, ugboro ole hypoglycemia na-ebelata. A na - ahụta nsonaazụ kacha mma na ndị agadi nwere ọrịa shuga 2, shuga ha nwere abụbeghị nke 33%.
- A na-ebelata ume na glucose n’ehihie.
- Ọnụ ọgụgụ insulin Tujeo na usoro 1 unit dị ntakịrị karịa Lantus.
Imirikiti nyocha ndị ọrịa shuga dị mma, nhọrọ nke ị whenụ ọgwụ mgbe ị na-agbanwe insulin dị mfe, ọ naghị ewe ihe karịrị otu izu.
Ndị ọrịa ahụ na-eji Tujeo eme ihe kwekọrọ na ntuziaka ndị ahụ na-ekwu maka ya dị ka ọgwụ dị elu, ma dị mfe iji.
Tujeo adighi enwe obi uto na ndi oria n’obara n’eji eji mkpịsị pen ede ọtụtụ oge. N'ihi ịba ụba ịba ụba, ọ na-adịkarị na crystallization, yabụ, ọ nwere ike ibochi oghere na agịga.
Nzaghachi ahụ mmadụ nyere Toujeo bụ nke onwe ya, dịka insulin ọ bụla. Fọdụ ndị ọrịa na-eche n ’enweghị ike ịtụtụrụ ọgwụ a, sụchaa shuga, mmụba na mkpa insulin dị mkpụmkpụ, na ịba ụba n’arụ ahụ, yabụ ha na-alaghachi n'iji Lantus.
Ntụgharị sitere na Lantus ruo Tujeo
N’agbanyeghi otu ihe mejuputara n’ime insulin, Tujeo insulin aputaghi na Lantus. Ntụziaka eji eme ihe na-egosi na ịnweghị ike iji ọgwụ ọzọ dochie ya. Ọ dị mkpa ịhọrọ ọgwụ ọhụrụ na nchịkwa glycemic ugboro ugboro n'oge a.
Uzo esi aga na Lantus gaa Tujeo nwere ọrịa shuga:
- Anyị na-ahapụ ọgwụ mbụ ahụ agbanweghị, ọ bụrụ na anyị nwere ọtụtụ Tujeo dị ka Lantus dị. Olu nke ihe ngwọta ga-abụ ugboro 3 obere.
- Agbanwela oge ntụtụ.
- Anyị na-enyocha glycemia ruo ụbọchị 3, oge nke insulin na-amalite ịrụ ọrụ zuru oke.
- Anyị na-atụle shuga ọ bụghị naanị na afọ efu, kamakwa mgbe anyị risịrị nri. Lantus nwere ike dozie njehie ya na ịgbakọ carbohydrates na nri. Tujeo SoloStar anaghị agbaghara mmejọ ndị dị otú ahụ, yabụ, ọ ga - ekwe omume ịbawanye ọgwụ insulin dị mkpụmkpụ.
- Dabere na data enwetara, anyị na-agbanwe usoro onunu ogwu. Ọtụtụ mgbe ọ chọrọ ntakịrị (ihe ruru 20%) ịba ụba.
- Nghazi nke ọ bụla kwesiri ime ma ọ dịkarịa ala ụbọchị atọ ka nke agafere.
- A na-ahụ usoro a ga-esi mee ya mgbe ọ dị glucose n'oge ụra, n'ụtụtụ yana afọ efu, ka edobere ya n'otu ọkwa n'etiti nri.
Iji jide n'aka na usoro nchịkwa gị, ị ga-agbasochi usoro ntụtụ ahụ anya. Tupu ntụtụ ahụ, ịkwesịrị ịhapụ mpaghara insulin iji chọpụta arụmọrụ nke mkpụrụ sirinji na patility nke agịga.
Biko rụba ama: You rọrọ iji kpochapụ ọrịa shuga otu oge? Mụọ otu esi emeri ọrịa ahụ, na-eji ọgwụ ọgwụ ndị dị oke ọnụ, na-eji naanị ... >> gụkwuo ebe a
Tujeo insulin na-arụ ọrụ ogologo oge - usoro iji ya, ihe ngosipụta, usoro onunu ogwu na nyocha
Ọtụtụ mmadụ na-arịa ọrịa shuga. Mgbasa nke ọrịa ahụ na-eduga n'eziokwu ahụ bụ na ụlọ ọrụ ọgwụ na-emepụta ndị na-agwọ ọrịa ọhụrụ na-eme ka ndị ọrịa nwee ike ibi ndụ dị mma.
Otu n'ime ọgwụ ọgbara ọhụrụ bụ Tujeo, nke ụlọ ọrụ German Sanofi mebere glargine mepụtara.
Ewepụtara ya site na inje subcutaneous, insulin Tujeo na-enyere aka ịchịkwa ọkwa shuga dị ọbara n'ụzọ ziri ezi, na-ezere ọnụ ya kachasị elu, na-ezere hyperglycemia na nsogbu ahụike ndị ọzọ.
Tujo SoloStar
Tujeo mepụtara ọgwụ ahụ bụ ụlọ ọrụ German Sanofi. E mepụtara ya na ntọala nke glargine, nke na-agbanwe ya ka ọ bụrụ insulin na-ewepụta ọkwa nke mmiri ogologo oge, nke nwere ike ijikwa ọkwa shuga ọbara nke ọma, na-egbochi mgbanwe ya na mberede.
Tujeo enweghị ihe ọ bụla ọ na-akpata, ebe enwere isi mgbapụta siri ike. Enwere ike izere nsị na mmetụta ndị na-adịghị mma na sistemụ akwara na akwara. Tujeo adabara maka ọgwụgwọ ụdị oria 1 na ụdị nke abụọ. Akụrụngwa nke ọgwụ ahụ bụ glargin 300, a na-ewere ya ka ihe dị elu maka iji ya rụọ ọrụ ebe achọtara mmachi insulin na-arị elu. Yzọ ọgwụgwọ mbụ bụ Lantus. Site na Tujeo, ị nwere ike ijikwa ọkwa insulin n'ụzọ ziri ezi, belata dose na mpaghara nke ọdịda ahụ, nke na-eme ka injections ghara ịba uru ma na-eme ka mmịkọta nke ọgwụ ahụ dị site na anụ ahụ subcutaneous, na-eme ka ọ bụrụ otu na ngwa ngwa. Tujeo dị ka ngwọta na-enweghị ụcha, nke e bubere maka nchịkwa n'okpuru anụ ahụ, a na-ere ya na sirinji pen. Akụkụ bụ isi bụ insulin glargin 300 PIECES. N'ime ndị na-amụ banyere ya: Ngwa Usoro onunu ogwu Glycerol 20 mg Metacresol 2,70 mg Ihe ndozi zinc 0.19 mg Sodium hydroxide ruru pH 4.0 Hydrochloric acid Ruo pH 4.0 Mmiri ruru 1.0 ml
Pharmacodynamics na pharmacokinetics
Tujeo bụ analogue nke insulin mmadụ, nke enwetara site na ntugharị nke DNA nke nje. Isi mmetụta insulin bụ ịchịkwa oriri nke glucose ahụ.
Ọ na - ebelata ọkwa glucose, na - eme ka mmụba ya na anụ ahụ adipose na akwara ọkpụkpụ, na - abawanye mmepụta protein, na - egbochi njikọ glucose na lipolysis na sel.
Nsonaazụ ojiji nke ọgwụ Tujo SoloStar na-egosi na enwere ogologo oge nnabata, na-ewe ruo awa 36.
N'iji ya na glargine 100, ọgwụ ahụ gosipụtara oge ntụgharị uche dị nwayọ. N'ime ubochi ụbọchi Tujeo subcutaneous gasịrị, mgbanwe dị iche iche bụ 17.4%, nke bụ ihe ngosi dị ala.
Mgbe ogwu ogbugba gasịrị, glargine insulin na-enweta metabolism dị omimi n'oge e guzobere otu ụzọ metabolites na-arụ ọrụ M1 na M2. Plasma ọbara dị na nke a nwere saturation ka ukwuu na metabolite M1.
Thebawanye ọgwụ ahụ na-eduga na mmụba na sistemụ nke metabolite, nke bụ isi ihe na-eme ka ọgwụ ahụ pụta.
Ihe ngosi maka ojiji
Ọrịa shuga mellitus, nke a ga-agwọrịrị na insulin.
Nlekọta afọ ime afọ, úkwù na ogwe aka. Ekwesịrị ịgbanwe saịtị ntụtụ ọ bụla kwa ụbọchị iji gbochie ịmepụta scars na mmebi anụ ahụ dị n'okpuru ala. Okwu mmeghe nke akwara nwere ike ibute nnukwu ọrịa hypoglycemia.
Ọgwụ nwere mmetụta na-adịte aka ma ọ bụrụ na etinye ntụtụ n'okpuru anụahụ. Sing na-ewere insulin na-eji mkpịsị mkpụrụ sirinji, ntụtụ gụnyere ihe dị ka nkeji iri asatọ.
Ọ ga-ekwe omume iwelie dose n'oge eji pen na-abawanye na 1 unit.
Edebere mkpịsị akwụkwọ a maka Tujeo, nke na-ewepụ mkpa iji weghachi ọgwụ onunu ogwu. Sirinji nkịtị nwere ike iji ọgwụ bibie kateeti ahụ, ọ gaghịkwa enye gị ohere ịlele insulin nke ọma. Enwere ike iwepu agịga ahụ ma were ya dochie ya.
Sirinji na-arụ ọrụ n'ụzọ ziri ezi ma ọ bụrụ na dobe insulin na-apụta n'ọnụ ọnụ agịga. N’iji mkpa nke agịga insulin dị, enwere ihe ize ndụ nke mgbochi ha n’oge a na-eme nke abụọ, nke na-agaghị ekwe ka onye ọrịa nwee ike nweta insulin ahụ kpọmkwem.
Enwere ike iji mkpịsị akwụkwọ ahụ otu ọnwa.
Ntụziaka pụrụ iche
Ndị na-arịa ọrịa shuga kwesịrị ilebara mkpokọ glucose ha anya, nwee ike ịme injections subcutaneous n'ụzọ ziri ezi, wee kwụsị hypoglycemia na hyperglycemia.
Onye ọrịa ahụ kwesịrị ịnọ na nche mgbe niile, leruo onwe ya anya n'oge ọgwụgwọ insulin maka ihe ga - eme ọnọdụ ndị a.
Ndị ọrịa na-arịa ọrịa akụrụ kwesịrị ịma na mkpa nke homonụ na-ebelata oge ụfọdụ n'ihi mbelata metabolism metabolism na mbelata ikike gluconeogenesis.
Njikọ Ọgwụ
Drugsfọdụ ọgwụ nwere ike imetụta metabolism nke glucose. Ọ bụrụ na akpọrọ ha na homonụ, mgbe ahụ ọ ga-adị mkpa ịkọwapụta otu ọnụọgụ ọgwụ.
N'ime ọgwụ ndị nwere ike ịbawanye mmetụta hypoglycemic nke insulin ma nye aka na mmalite nke hypoglycemia bụ fluoxetine, pentoxifylline, ọgwụ mgbochi sulfonamide, fibrates, ACE inhibitors, MAO inhibitors, viopyramide, propoxyphene, salicylates. Ọ bụrụ na ị were ego ndị a n'otu oge dịka glargine, ị ga-achọ mgbanwe mgbanwe onunu ogwu.
Ọgwụ ndị ọzọ nwere ike ime ka mmetụta hypoglycemic nke ọgwụ dịkwuo ike.
Themfọdụ n’ime ha bụ Isoniazid, glucocorticosteroids, homonụ na-eto, protein inhibitors, ọgwụ na phenothiazine, Glucagon, sympathomimetics (Salbutamol, Terbutaline, Adrenaline), estrogens na progestogens, gụnyere ndị dị na mgbochi ọgwụ homonụ, homonụ thyroid, atyroid glands diure, antipsychotics (clozapine, olanzapine), diazoxide.
Mgbe ejiri ya na ethanol, clonidine, salhi lithium ma ọ bụ ndị na-egbochi beta, mmetụta homonụ nwere ike ịbawanyewanye ike. Iji Pentamidine mee ihe mgbe ụfọdụ nwere ike ibute hypoglycemia, na-agbanwekarị hyperglycemia. Ojiji pioglitazone ya na homonụ na-adịghị ahụkebe nwere ike iduga na ngosipụta nke nkụda obi.
Ngwurugwu mgbochi na nsonaazụ ya
Ekwesighi iji ogwu a ma o buru na mmadu enwere ihe ndi ozo. Tujeo kwesịrị ekwesị maka ndị okenye naanị. Ekwesịrị iji nlezianya mee ihe n'ime ụmụ nwanyị dị ime, ndị nwere nsogbu endocrine na afọ ezumike nká. Tujeo adabara adighi ọrịa ketoacidosis nke na-arịa ọrịa shuga. Nsonaazụ ndị a na-esokarị gụnyere:
- mmeghachi omume nfụkasị ahụ
- lipodystrophy,
- I nweta ibu
- mmebi anya
- myalgia
- hypoglycemia.
Usoro ire na ebe nchekwa
Enyere ọgwụ a n'ụlọ ahịa ọgwụ nwere ndenye ọgwụ. Ọ dị mkpa ịchekwa n’ebe echekwara site n’ìhè, okpomọkụ kwesịrị ịdị n’agbata 2-8 Celsius. Zonahụ ụmụ. Mgbe ị na-echekwa ọgwụ, ọ dị mkpa ijide n'aka na nkwakọ nke pensụl anaghị abanye na friza, ebe insulin enweghị ike ịjụ oyi.. Mgbe ojiji nke mbụ gasị, chekwaa ọgwụ a karịa izu anọ.
Analogs nke insulin Tujeo
Uru nke ọgwụ a na-enweta n'elu analogues doro anya. Oge a dị ogologo (n'ime awa iri abụọ na anọ ruo iri abụọ na anọ), na obere nri, yana ịchịkwa usoro nke glucose ọbara dị iche iche (ọ bụ ezie na enwere ntakịrị irighiri), na oge injections enweghị ike ịhụ ya nke ọma. Otu n'ime analogues nke insul insal nke ọgbọ ọhụrụ: