Thioctacid BV > Ọgwụgwọ na mgbochi

Thioctacid BV: ntuziaka maka ojiji na nyocha

Aha Latin: Thioctacid

Koodu ATX: A16AX01

Ngwakọta ọrụ: thioctic acid (thioctic acid)

Onye na-emepụta: Nrụpụta GmbH MEDA (Germany)

Mmelite nke nkọwa na foto: 10.24.2018

Ego dị n'ụlọ ahịa ọgwụ: site na 1605 rubles.

Thioctacid BV bụ ọgwụ metabolic nwere mmetụta antioxidant.

Mwepụta wepụtara ya na ihe mejupụtara

Thioctacid BV dị n'ụdị mbadamba ụrọ nwere ihe mkpuchi fim: akwụkwọ ndụ akwụkwọ ndụ-odo, oblong biconvex (30, 60 ma ọ bụ 100. Na karama gbara ọchịchịrị, otu karama 1 na kaadiboodu).

Otu mbadamba 1 nwere:

ihe na-arụ ọrụ: thioctic (alfa-lipoic) acid - 0.6 g,
ihe inyeaka: magnesium stearate, hyprolose, hyprolose dị ala,
ihe mkpuchi ihe nkiri: titanium dioxide, macrogol 6000, hypromellose, aluminom varnish dabere na indigo carmine na dye quinoline odo, talc.

Mlọ ọgwụ

Thioctacid BV bụ ọgwụ metabolic na-eme ka neurons trophic dị elu, nwee ọrịa hepatoprotective, hypocholesterolemic, hypoglycemic, na mmetụta dị ala.

Ihe na-arụ ọrụ nke ọgwụ ahụ bụ thioctic acid, nke dị na ahụ mmadụ ma bụrụkwa antioxidant endogenous. Dịka coenzyme, ọ na-esonye na ọgwụ oxidative phosphorylation nke pyruvic acid na alfa-keto acids. Usoro ihe nke thioctic acid dị nso na mmetụta biochemical nke vitamin B Ọ na - enyere aka ichebe mkpụrụ ndụ site na nsonaazụ nsonaazụ nke radicals na - apụta na usoro metabolic, na - egbochi ihe ndị na - egbu egbu nke batara ahụ. Bawanye ọkwa nke antioxidant antioxidant glutathione, na-ebute mbelata ogo ihe mgbaàmà nke polyneuropathy.

Mmetụta mmekọrịta nke thioctic acid na insulin bụ mmụba nke itinye glucose.

Mlọ ọgwụ

Ntinye nke thioctic acid site na eriri afọ (GIT) mgbe ejiri ọnụ na-eme ya na-apụta ngwa ngwa na kpamkpam. Iji ọgwụ a were nri nwere ike belata mmịpụta ya. C_max oke itinye uche na plasma ọbara mgbe ewerechara otu ihe na - enweta ya mgbe nkeji iri atọ ma ọ bụ 0.004 mg / ml. Ezigbo bioavailability nke Thioctacid BV bụ 20%.

Tupu abanye n'ọbara sistem, thioctic acid na-enwe mmetụta nke akụkụ nke mbụ gafere site na imeju. Mainzọ nke ụzọ nke metabolism ya bụ oxidation na conjugation.

Ndi_1/2 (ọkara ndụ) bụ nkeji iri abụọ na ise.

Mwepu nke ihe na - arụ ọrụ bụ Thioctacid BV na metabolites ya na-arụ site na akụrụ. Site na mmamịrị, 80-90% nke ọgwụ na-adị.

Ntuziaka maka iji Thioctacid BV: usoro na usoro onunu ogwu

Dịka ntuziaka ahụ si dị, a na-ewere Thioctacid BV 600 mg n'ime afọ efu n'ime, awa 0,5 tupu nri ụtụtụ, na-elo ihe niile ma drinkingụọ nnukwu mmiri.

Usoro a tụrụ aro: 1 pc. Otu ugboro n'ụbọchị.

N'iburu ikike ogwu a, maka ọgwụgwọ nke ụdị polyneuropathy dị njọ, nchịkwa mbụ nke ihe ngwọta nke thioctic acid maka nchịkwa intravenous (Thioctacid 600 T) ga - ekwe omume maka oge nke ụbọchị iri na anọ ruo ụbọchị iri abụọ na asaa, nke a na - esote onye ọrịa na ị intụ ọgwụ kwa ụbọchị (Thioctacid BV).

Nsonaazụ

site na nri digestive: ọtụtụ mgbe - ọgbụgbọ, obere adịkarịghị - vomiting, mgbu afọ na eriri afọ, afọ ọsịsa, mebiri nke sensations
site na ụjọ usoro: oge ụfọdụ - akpịrị,
mmeghachi omume nfụkasị ahụ: ọ dịkarịsịrị - itching, ọnya anụ ahụ, urticaria, urepula anafilactic,
site na anụ ahụ n'ozuzu ya: ọ dịkarịsịrị ike - mbelata ọbara glucose, ọdịdị nke ihe mgbaàmà hypoglycemia n'ụdị isi ọwụwa, ọgba aghara, ịba ụba ịba ụba, na nkwarụ anya.

Dodoụbiga ya ókè

Mgbaàmà: megide nzụlite otu mkpụrụ ọgwụ nke 10-40 g nke thioctic acid, mmerụ ahụ siri ike nwere ike ịmalite site na ngosipụta dịka njiri amamịghe juputara n'ọbara, hypoglycemic coma, oke nsogbu nke acid-base balance, lactic acidosis, nsogbu ọbara ọgbụgba siri ike (gụnyere ọnwụ).

Ọgwụ: ọ bụrụ na a na-enyo enyo enyo nke Thioctacid BV (otu mkpụrụ maka ndị okenye karia mbadamba 10, nwatakịrị karịrị 50 mg kwa 1 kilogram nke ahụ ya), onye ọrịa ahụ chọrọ ụlọ ọgwụ ozugbo yana nhọpụta nke usoro ọgwụgwọ Symptomatic. Ọ bụrụ na ọ dị mkpa, a na-eji usoro ọgwụgwọ anticonvulsant eme ihe, usoro mberede chọrọ iji nọgide na-arụ ọrụ nke akụkụ ahụ dị mkpa.

Ntụziaka pụrụ iche

Ebe ethanol bụ ihe dị egwu maka mmepe nke polyneuropathy ma na-ebute mbelata ọgwụgwọ Thioctacid BV, oriri mmanya na-egbochi ndị ọrịa.

Na ọgwụgwọ polyneuropathy na-arịa ọrịa shuga, onye ọrịa ahụ kwesịrị ịmepụta ọnọdụ ndị na-ahụ maka ịkwado ọkwa glucose dị n'ọbara.

Dị mwepụta, nkwakọ na ngwakọta Thioctacid ® BV

Mbadamba ụrọ, odo na-acha akwụkwọ ndụ akwụkwọ ndụ, oblong, biconvex.

Taabụ 1
acid (α-lipoic) acid	600 mg

Ndị pụrụ iche: hyprolose dị ala - 157 mg, hyprolose - 20 mg, magnesium stearate - 24 mg.

Ihe mejupụtara nke uwe ihe nkiri ahụ: hypromellose - 15,8 mg, macrogol 6000 - 4.7 mg, titanium dioxide - 4 mg, talc - 2.02 mg, aluminom varnish dabere na acha odo odo quinoline - 1.32 mg, aluminom varnish dabere na indigo carmine - 0.16 mg.

30 PC - karama iko gbara ọchịchịrị (1) - ngwugwu nke kaadiboodu.
60 pcs. - karama iko gbara ọchịchịrị (1) - ngwugwu nke kaadiboodu.
100 pcs - karama iko gbara ọchịchịrị (1) - ngwugwu nke kaadiboodu.

Mkparịta ụka ọgwụ ọjọọ

Iji n'otu oge eji Thioctacid BV:

cisplatin - na-agbada mmetụta ọgwụgwọ ya,
insulin, ọnya hypoglycemic na-elekọta mmadụ - nwere ike ịkwalite nsonaazụ ha, yabụ, achọrọ nlebara anya glucose ọbara dị larịị, ọkachasị na mmalite nke ọgwụgwọ njikọta, ọ bụrụ na ọ dị mkpa, a na-anabata mbelata ọgwụ nke hypoglycemic ọgwụ,
ethanol na metabolites ya - kpatara ike ịgwụ ọgwụ.

Ọ dị mkpa iburu n'uche ngwongwo nke thioctic acid na njikọta nke ọla mgbe ejikọtara ya na ọgwụ ndị nwere iron, magnesium na ọla ndị ọzọ. A na-atụ aro ka mbanye ha ruo mgbe ehihie.

Nyocha na Thioctacide BV

Nyocha nke Thioctacide BV na-enwekarị echiche ziri ezi. Ndị ọrịa nwere ọrịa shuga na-egosi mbelata ọbara shuga na ọkwa cholesterol, ahụike dị mma megide mmalite nke iji ọgwụ ogologo oge. Otu akụkụ nke ọgwụ ahụ bụ mwepụta ngwa ngwa nke thioctic acid, nke na-enyere aka mee ka usoro metabolic dịkwuo elu na iwepu abụba na-enweghị afọ ojuju, ntụgharị nke carbohydrates na ike.

E gosipụtara mmetụta ọgwụgwọ dị mma mgbe ị na-eji ọgwụ maka ọgwụgwọ nke imeju, ọrịa akwara, oke ibu. N'iji ya tụnyere analogues, ndị ọrịa na-egosi ntakịrị ọnọdụ nke nsonaazụ achọghị.

N'ime ụfọdụ ndị ọrịa, ị theụ ọgwụ ahụ enweghị mmetụta a tụrụ anya ya na iwelata cholesterol ma ọ bụ tinye aka na mmepe nke urticaria.

Omume ọgwụ

Ọgwụ Metabolic. A na-ahụ acid Thioctic (α-lipoic) n'ime ahụ mmadụ, ebe ọ na-eme dị ka coenzyme na phoidhosị oxidative nke pyruvic acid na alpha-keto acid. Thioctic acid bụ ọgwụ antioxidant na-egbu egbu; dịka usoro biochemical si arụ ọrụ, ọ dị nso na vitamin B.

Thioctic acid na - enyere aka ichekwa mkpụrụ ndụ site na nsonaazụ nsonaazụ nke radicals na - apụta na usoro metabolic, ọ na - ewepụkwa ihe egwu mmiri na - emetụta ahụ. Acid Thioctic na-eme ka ịba ụba nke endogenous antioxidant glutathione, nke na-eduga n'ịbelata ogo ihe mgbaàmà nke polyneuropathy.

Ọgwụ nwere hepatoprotective, hypoliplera, hypocholesterolemic, hypoglycemic utịp, na-eme ka akwara trophic neurons dịkwuo mma. Ihe mmekọrịta nke thioctic acid na insulin na-ebute na ịba ụba glucose.

Ngwakọta, nkọwa, ụdị na nkwakọ ngwaahịa ọgwụ

You nwere ike ịzụta ọgwụ ahụ n'ụdị abụọ dị iche iche:

Nkwadebe ọnụ "Thioctacid BV" (mbadamba). Ntụziaka maka iji ya na-ekwu na o nwere udi convex, yana shei odo ma ọ bụ nke nwere agba akwụkwọ ndụ akwụkwọ ndụ. N'ihe ire, mbadamba ihe di otua na abia n’osisi iri ato. Ihe dị n'ọrụ a bụ thioctic acid. Ọgwụ a gunyere ihe ndị ọzọ n'ụdị nke obere hydroxypropyl cellulose, magnesium stearate, hydroxypropyl cellulose, hypromellose, macrogol 6000, quinoline salt aluminom, titanium dioxide, talc na indigo carmine aluminom salts.
Ngwọta "Thioctacid BV" 600. Ntụziaka maka iji akụkọ na-akọ na ụdị ọgwụ a ezubere iji gbaa ya ọgwụ. Ngwọta doro anya bụ edo edo ma dị na ampoules iko gbara ọchịchịrị. Ngwaọrụ ya na-arụ ọrụ bụkwa thioctic acid. Dika ihe ndi ozo, ejiri mmiri na trometamol di ọcha.

Ọgwụ Farmacology

N'ime ahụ mmadụ, thioctic acid na-arụ ọrụ nke coenzyme, nke na - etinye aka na mmeghachi nke oxidative nke phosphorylation nke alpha-keto acid, yana pyruvic acid. Na mgbakwunye, ọ bụ antioxidant endogenous. Site n'usoro iwu ya (biochemical), akụkụ a dị nso na vitamin B.

Dị ka ndị ọkachamara si kwuo, thioctic acid na-echebe mkpụrụ ndụ site na nsonaazụ nsonaazụ nke radicals na-etolite n'oge metabolism. Ọ na - enyere aka ịkwụsị ihe ndị na - egbu egbu mmiri na - abanye ahụ mmadụ.

Ngwongwo ogwu

Gịnị bụ Njirimara nke ọgwụ "Thioctacid BV 600? Ntuziaka maka iji akụkọ na-ekwupụta na thioctic acid na-enwe ike ime ka mkpocha nke antioxidant dị otú ahụ dị ka glutathione. Mmetụta yiri nke a na-eduga na mbelata nke nnukwu ihe mgbaàmà nke polyneuropathy.

Ọ gaghị ekwe omume ịsị na ọgwụ a na-ekwu okwu nwere mmetụta hypoglycemic, hepatoprotective, hypocholesterolemic na hypolipPs. O nwekwara ike imeziwanye neurons trophic.

Mmetụta mmekọrịta nke thioctic acid na insulin na-abawanye uru glucose.

Ihe ngbanwe

N'ihi enweghị ahụmịhe zuru oke na iji ngwa a na ọmụmụ ụlọ ọgwụ, a naghị atụ aro ịhọpụta ya nye ndị nne na-elekọta nwa na ụmụ nwanyị dị ime.

Ọ ga - ekwe omume inye nwatakịrị ọgwụ "Thioctacid 600BV"? Amachibidoro iji ọgwụ a na ụmụaka na ndị nọ n’oge uto. Ọzọkwa, ekwesighi iji ya mee ihe nfụkasị ọ bụla na mmiri.

Mmeghachi omume ọjọọ

Site na nchịkwa nke ọgwụ ahụ, onye ọrịa ahụ nwere ike ịmalite ụdị arụmọrụ dịka:

mmeghachi omume nfụkasị ahụ n'ụdị ihe ọkụ ọkụ na itching na anụ ahụ, yana urticaria,
nsonaazụ sitere na ngwara nri (afọ ọsịsa, ọgbụgbọ, mgbu na ọgbụgbọ).

Ma ụdị inject, ọ na-ebute:

ọnyá akpukpo aru, ujo na itching,
ume iku ume na mgbali dị elu (intracranial),
ọbara ọgbụgba, ọnya ọgbụgba, nsogbu ọhụụ, na obere ọbara ọgbụgba.

Ikpe nke ọgwụ ịdoụbiga mmanya ókè

Ọ bụrụ na ọgwụ ndị a tụrụ aro ka gafere karịa, onye ọrịa ahụ nwere ike ịmalite mgbaàmà dịka nkwarụ, lactic acidosis, nsogbu ọbara ọgbụgba na coma hypoglycemic.

Mgbe ị na-ahụ mmeghachi omume ndị dị otú ahụ, ị kwesịrị ịkpọtụrụ dọkịta, ma tinyekwa ọgbụgbọ na onye ọzọ merụrụ ya, nye ya enterosorbents ma hichaa afọ gị. Ekwesịrị ịkwado onye ọrịa ahụ ruo mgbe ụgbọ ihe mberede rutere.

Mpempe usoro onunu ogwu

Mpempe akwụkwọ mkpuchi 600 mg

Otu mbadamba ihe

ike - ọgwụ thioctic acid (alfa lipoic) 600 mg,

ndị na-ebu ụzọ: sel cellolose hydroxypropyl dị ntakịrị, hydroxypropyl cellulose, magnesium stearate,

hypromellose, macrogol 6000, titanium dioxide (E 171), talc, quinoline odo (E 104), indigo carmine (E 132).

Mbadamba ụrọ, akwụkwọ ndụ akwụkwọ ndụ na-acha odo odo na-acha akwụkwọ ndụ akwụkwọ ndụ, nwere ọdịdị biconvex.

Analogs na ọnụ ahịa

Dochie ọgwụ dịka Thioctacid BV site na ọgwụ ndị a: Berlition, Alpha Lipon, Dialipon, Tiogamma.

Banyere ọnụahịa ahụ, ọ nwere ike ịdị iche maka ụdị dị iche iche na ndị nrụpụta. Ọnụ ego ụdị mbadamba mbadamba nke "Thioctacid BV" (600 mg) bụ ihe dị ka 1700 rubles kwa 30. Enwere ike ịzụta ọgwụ n'ụdị ihe ngwọta maka 1,500 rubles (maka iberibe 5).

Nyocha banyere ọgwụ

Dị ka ị maara, ọgwụ a "Thioctacid BV" bụ maka ndị mmadụ na-arịa ajọ ọrịa metabolism. Nyocha nke ndị ọrịa gbasara ụdị mbadamba ihe bụ ihe atụ. Dabere na akụkọ ha, ngwá ọrụ a dị nnọọ irè. Mana ọ bụ ihe nwute, mbadamba nkume na-ebutekarị mmeghachi omume dị njọ, nke na-egosipụta onwe ha n'ụdị ọgbụgbọ, urticaria, na mgbe ụfọdụ ọbụna n'ụdị ọkụ ọkụ na mgbanwe na ọnọdụ onye ọrịa na ọnọdụ.

Ugbu a ịmara ihe ọgwụ “Thioctacid BV 600” nọchiri anya

Nyocha banyere usoro ọgwụgwọ a kpọtụrụ aha na-ahapụ ọ bụghị naanị ndị ọrịa ahụ na-ewere ụdị mbadamba ya, kamakwa ndị edepụtara otu usoro ọgwụgwọ maka injection.

Dabere na akụkọ banyere ndị dị otú ahụ, nsonaazụ ya na nchịkwa ịba uru nke ọgwụ ahụ adịkarịghị ala. Ọzọkwa, a naghị ekwu ya dị ka mgbe a na-a takingụ ọgwụ.

Ya mere, enwere ike ibute ya na "Thioctacid BV" bụ ezigbo ọrụ dị mma iji lụso ihe ịrịba ama nke polyneuropathy nke bilitere mgbe ị ofụsịrị mmanya ogologo oge ma ọ bụ megide nzụlite ọrịa shuga mellitus.

Ngwongwo ogwu

Mlọ ọgwụ

Site na nchịkwa ọnụ, a na-enweta acid ngwa ngwa nke thioctic (alpha-lipoic) n'ime ahụ. N'ihi nkesa ngwa ngwa, anụ ahụ, ọkara ndụ thioctic (alfa-lipoic) acid na plasma ọbara dị ihe dị ka minit 25. Nlele anya kachasị nke plasma nke 4 μg / ml tụrụ ka awa 0,5 mgbe nchịkwa ọnụ nke 600 mg nke alfa lipoic acid. Drawepụ ọgwụ ọjọọ na - aputa ihe site na akụrụ, 80-90% - n'ụdị metabolites.

Mlọ ọgwụ

Acid Thioctic (alfa-lipoic) bụ antioxidant endogenous ma na - eme dị ka coenzyme na decarboxylation nke oxidative decarboxylation nke alpha-keto acid. Hyperglycemia kpatara ọrịa shuga na-eduga n'inweta glucose na protein nke matriks nke arịa ọbara na ịmepụta nke a na-akpọ "ngwaahịa ngwụsị nke glycation dị ukwuu." Usoro a na - eduga n'ịbelata ọbara ọbara endoneural na hypoxia-ischemia nke endoneural, nke a na - emeju na ịba ụba nke ụzarị oxygen enweghị oke, nke na - eduga ná mbibi nke akwara ndị nwere oke na mbelata nke antioxidants dịka glutathione.

Usoro onunu ogwu na nhazi

Were 1 mbadamba Thioctacid 600BV otu ugboro kwa ụbọchị na otu iko, nkeji iri atọ tupu nri mbụ.

Buru afọ na-enweghị isi, na-enweghị ị ,ụ mmiri na ị cheụ ọtụtụ mmiri. Ejikọtara ya na oriri nri nwere ike belata mmịpụta nke alfa lipoic acid.

Ọ bụ dibia bekee ga-ekpebi oge ọgwụgwọ ọ bụla.

Mkparịta ụka ọgwụ ọjọọ

Enwere mbelata na arụ ọrụ nke cisplatin mgbe ejisiri thioctacid otu oge. Ekwenyeghi ọgwụ a n’otu oge, ya na iron, magnesium, potassium, oge etiti oge n’etiti usoro ọgwụ ndị a kwesịrị ịbụ ma ọ dịkarịa ala 5 awa. Ebe ọ bụ na enwere ike ịbawanye ike ịbawanye ike nke insulin ma ọ bụ ihe ndị na-egbu egbu na-enye ọgwụ ike, a na-atụ aro ịbanye na shuga ọbara mgbe niile, karịsịa mmalite nke Thioctacid 600BV. Iji zere ihe mgbaàmà hypoglycemia, ọ dị mkpa iji nlezianya nyochaa ọkwa nke glucose dị n'ọbara.

Mpempe akwụkwọ Mpempe akwụkwọ

MEDA Pharma GmbH & Co. KG, Germany

Adreesị nke nzukọ ahụ nke na-anabata ndị na-azụ ahịa banyere ogo ngwaahịa dị na Republic of Kazakhstan Onyinye nke MEDA Pharmaceuticals Switzerland GmbH na Republic of Kazakhstan: Almaty, 7 Al-Farabi Ave., PFC "Nurly Tau", ụlọ 4 A, office 31, tel. 311-04-30, 311-52-49, tel / faksị 277-77-32