Aha Latin: Hydrochlorothiazide

Koodu ATX: C03AA03

Ngwakọta ọrụ: Hydrochlorothiazide (Hydrochlorothiazide)

Analogs: Hypothiazide, Hydrochlorothiazide-SAR Hydrochlorothiazide-Verte, Dichlothiazide

Onye na-emepụta: Valenta Pharmaceuticals OJSC (Russia), Borshchagovsky HFZ (Ukraine), LEKFARM LLC, (Republic of Belarus)

Nkọwa gabigara na: 03/10/17

Ọnụahịa dị na ahịa ọgwụ n'ịntanetị:

Hydrochlorothiazide bụ ọgwụ eji eme ya maka ọrịa nke akụrụ, ngụgụ, umeji na obi iji belata edema.

Ihe ngosi maka ojiji

• ọbara mgbali ọbara (ọbara mgbali elu),
• ọrịa shuga insipidus (imebi nguzozi mmiri-nnu n’ime ahụ, nke mere n’ihi mbelata nke nzuzo nke homonụ antidiuretic),
• mkpọchi obi
• jade na nephrosis,
• cirrhosis nke imeju
• ilu okwute,
• nsogbu ime ime: mmebi akụrụ, edema, eclampsia (oke ọbara mgbali elu),
• ọrịa edematous nke sitere na ụzọ dị iche iche,
• compdị gbara nke glaucoma.

Ihe ngbanwe

• hypersensitivity na mmiri,
• ụkọ lactose, ụyọkọ galactosemia na ịpaụ ya nke galactose na glucose,
• ọria akwara na ọrụ ịba ọcha n'anya,
• ọrịa shuga siri ike, gout, anuria (enweghi usoro mmamịrị na eriri afo),
• hypercalcemia (calcium ọbara dị elu),
• systemic lupus erythematosus, pancreatitis.

Nsonaazụ

Ojiji hydrochlorothiazide nwere ike ibute nsogbu ndị a:

• vomiting, ọgbụgbọ, anorexia, akọrọ akọrọ, dyspepsia (ọgba aghara nri),
• ọrụ imeju, jaundice, cholecystitis (mbufụt nke ọnya afọ), pancreatitis (mbufụt nke pancreas),
• ihe ọdịdọ, ọgba aghara, ike ọgwụgwụ, mbelata nke mgbakasị ahụ, iwe iwe, ike ọgwụgwụ,
• ike ọgwụgwụ, ọgba aghara nke obi, thrombocytopenia, agranulocytosis,
• urticaria, itching skin, photoensitivity (ịmụba na nwute ọkụ),
• libido belatara, ikike nwere nsogbu, mgbu mgbu, hypokalemia (ọkwa dị ala nke ion potassium dị n'ọbara).

Dodoụbiga ya ókè

Bụrụ na ị doụfere hydrochlorothiazide, nnabata ndị dị otú ahụ nwere ike ime:

• ọgbụgbọ, adịghị ike,
• anya ntughari
• oke nsogbu na mmiri-electrolyte,
• mgbaka nke gout.

Enweghị ọgwụ mgbochi akọwapụtara. Edere usoro ọgwụgwọ na akara nke mmiri-electrolyte na ahụ.

N'ọnọdụ hypokalemia, a na-atụ aro iji potassium chloride ma ọ bụ asparkam. Mgbe ụfọdụ enwere ike ịmebe hyperchloremic alkalosis (mgbanwe nke metabolism electrolyte). A gwaziri onye ọrịa iwebata 0,5% saline (sodium chloride). N'ihe banyere ngosipụta dị nro nke gout, a na-eji allopurinol.

Mgbe ị na-a largeụ ọgwụ ndị gbara ọkpụrụkpụ, onye ọrịa, n’adaghị ada, ga-anọrịrị n’ụlọ ọrụ ahụike n’okpuru nlekọta nke ndị ọkachamara.

Hypothiazide, Hydrochlorothiazide-ATS Hydrochlorothiazide-Verte, Dichlothiazide.

Omume ọgwụ

Mmetụta diuretic hydrochlorothiazide dị n'ike ya iji sọpịlị potassium, bicarbonate na magnesium ion rụọ ọrụ.

• Na-enye mbelata reabsorption (mwepu azu) nke mmiri mmiri, chlorine na sodium ion na the distal tubules. Ọ na-arụ ọrụ na tubules distal, na -ebelata mpụta nke calcium ma na-egbochi nguzobe nke calcium na akụrụ.
• Na-eme ka ikike ịta akụrụ dịkwuo ukwuu, na-egbochi ike nke mgbidi arịa ọbara iji mee ihe nke ndị mgbasa ozi, bụ ndị na-etinye aka na ntinye nke mkpịsị akwara. A na-ejikwa mbadamba na ọgwụgwọ nke ndị mmadụ na-anata ọgwụgwọ na ndị ọrụ homonụ (estrogens, corticosteroids).
• Ejiri ya hypotensive, yana belata oke mmamịrị n’etiti ndị nwere ọrịa insipidus. Na mgbakwunye, ọgwụ ahụ n'ọnọdụ ụfọdụ nwere ike belata nrụgide intraocular.
• Mgbe nchịkwa ọnụ gasịrị, ọ na-etinye ahụ nke ọma na eriri afọ ma kpụta ya na akụrụ ya fọrọ nke nta ka ọ gbanwee.
• A na-ahụkarị arụmọrụ kachasị elekere 4 mgbe nchịkwa ma na - ewere ọnọdụ n'ime elekere 12 ọzọ. Ọ bụ ike gabiga Plasenta na banye na mmiri ara.

Ntụziaka pụrụ iche

• N'iche oke nlezianya anya, a na-enye ya ọgwụ maka ndị ọrịa agadi, ndị ọrịa atherosclerosis nke arịa nke obi na ụbụrụ yana yana ọrịa shuga.
• N'oge ọgwụgwọ, ọ dị mkpa iji zere ikpughe anyanwụ ruo ogologo oge, ebe ọ bụ na ọgwụ ahụ na-eme ka ịba ụba nke anụ ahụ na radieshon ultraviolet.
• Enwere ike ịkọ ọgwụ ogwu naanị mgbe ejiri nlezianya nyocha nke uru ihe ọ bụla dị na ndị ọrịa na-arịa metabolism na-akpata ahụ, ụba nke triglycerides na cholesterol na plasma ọbara, yana yana sodium dị ala n'ime ahụ.

Mkparịta ụka ọgwụ ọjọọ

• N'iji oge nke ndị na - eme ihe na - emegharị ahụ, ndị na - eme ihe na - egbochi ọgwụ, a na - eme ka mmetụta ha dịkwuo mma.
• Mgbe ejikọtara ya na corticosteroids, enwere nsogbu hypokalemia na hyperension orthostatic.
• N'iji oge nke ethanol, diazepam, barbiturates, ihe ọghọm nke ịmalite hyicension orthostatic na-abawanye.
• Site na nchịkwa mgbagwoju anya na ndị na - egbochi ACE, a na - eme ka mmetụta antihypertensive dịkwuo mma.
• Site na nhazi oge nke ọgwụ hypoglycemic ọgwụ, arụmọrụ ha na-ebelata.

Hydrochlorothiazide

Aha Latin: Hydrochlorothiazide

Koodu ATX: C03AA03

Ngwakọta ọrụ: hydrochlorothiazide (Hydrochlorothiazide)

Onye na-emepụta ihe: Atoll LLC (Russia), Pharmstandard-Leksredstva OJSC (Russia), Pranafarm LLC (Russia)

Nkọwa na nwelite: 07/10/2019

Ahịa dị n'ụlọ ahịa ọgwụ: site na 42 rubles.

Hydrochlorothiazide bụ ọrịa diuretic.

Mwepụta wepụtara ya na ihe mejupụtara

Mpempe usoro onunu ogwu - mbadamba: okirikiri, cylindrical, nke nwere oghe n’otu akụkụ na ogwe uzo n’ahia, nke dikariri ocha ma obu ocha (iri abuo n’abuo na iri, 10, 20, 30, 40, 50, 60 na 100 pcs na Mkpọ, na ngwungwu mkpọchi nke 1, 2, 3, 4, 5, 6, 10 ma ọ bụ 1 nwere ike na ntuziaka maka ojiji nke hydrochlorothiazide).

Ngwakọta 1 mbadamba:

• ihe na-arụ ọrụ: hydrochlorothiazide - 25 ma ọ bụ 100 mg,
• ihe inyeaka: stachi ọka, microcrystalline cellulose, lactose monohydrate (shuga mmiri ara ehi), magnesium stearate, povidone-K25.

Mlọ ọgwụ

Hydrochlorothiazide bụ ọkara ọgwụ thiazide diuretic.

Ọgwụ na-ebelata reabsorption nke sodium na mpaghara cortical nke loop nke Henle, ebe ọ naghị emetụta akụkụ ya na-agafe na ụbụrụ akụrụ. Nke a na - akọwa mmetụta adịghị ike diuretic hydrochlorothiazide karịa furosemide.

Hydrochlorothiazide na-egbochi carbon anhydrase na proximal tubules a na-ejikọ ọnụ, na-eme ka mkpụrụ ndụ nke hydrocarbons, phosphates, na potassium dị (na distal tubules, sodium gbanwere maka potassium). Na -eme ka mmanu calcium na aru ma wepu urate. Na-eme ka excisetion nke magnesium. Ihe fọrọ nke nta ka ọ ghara inwe mmetụta dị na steeti acid-base (a na-ekepụ sodium na chlorine ma ọ bụ na bicarbonate, yabụ, na acidosis, a na-eme ka mpụ nke chlorides, yana alka alka - bicarbonates).

Mmetụta diuretic nke hydrochlorothiazide na - etolite n'ime awa 1-2 mgbe ị takingụsịrị ọgwụ ahụ, ruru oke mgbe awa 4 gachara, wee ruo awa 6-12. Mmetụta ahụ na-ebelata mbelata nke mmamịrị ọgbụgba ụwa, na uru 2 nke anụ ahụ dị elu 1 oge kwa ụbọchị. Ngụkọta ụbọchị kwa ụbọchị maka ụmụaka 3-12 dị afọ nwere ike site na 37.5 ruo 100 mg. Mgbe ọ gwasịrị ụbọchị 3-5 ọgwụgwọ, a na-atụ aro ka ya ezumike maka otu ụbọchị ahụ. Site na ọgwụgwọ mmezi, a na-a theụ ọgwụ ahụ na ọgwụ a tụrụ aro ya ugboro 2 n'izu. N'ime ndị ọrịa na-anata usoro ọgwụgwọ oge na Hydrochlorothiazide otu ugboro n'ime ụbọchị 1-3 ọ bụla ma ọ bụ nwee nchịkwa maka ụbọchị 2-3 na-esochi oge ezumike, mmeghachi omume na-adịghị ala ala, ọ na-esiri ike ịgwọ ya ọgwụgwọ.

Nsonaazụ

A na-ekewa nsonaazụ ndị a kọwara n'okpuru ebe a dabere na oge mmepe dị ka ndị a: ọtụtụ mgbe - karịa 1/10, ọtụtụ mgbe karịa 1/100, mana erughi 1/10, ugboro ugboro - karịa 1/1000, mana erughị 1/100, adịkarịghị - karịa 1 / 10 000, mana erughi 1/1000, dịkarịsịrị obere - erughi 1/10 000, gụnyere ozi nkeonwe:

• ọghọm nke mmiri-electrolyte nguzozi: mgbe - hypercalcemia, hypomagnesemia, hypokalemia, hyponatremia (nke gosipụtara na nkwonkwo akwara, ike ọgwụgwụ, usoro echiche, iwe iwe, mgbakasị ahụ, ọgba aghara, ọdịdọ), hypochloremic alkalosis (nke akpịrị mucous membrane, gosipụtara na akpịrị, akpịrị) , ọgbụgbọ, ọgbụgbọ, mgbanwe na ọnọdụ na psyche, arrhythmia, cramps and pain mgbu, adịghị ike ma ọ bụ ike ọgwụgwụ pụrụ iche), nke nwere ike ibute hepatic e tsefalopatiyu ma ọ bụ hepatic Coma,
• nsogbu nke metabolic: ọtụtụ mgbe - glucosuria, hyperglycemia, hyperuricemia na mmepe nke mwakpo nke gout, mmepe nke nnabata glucose, ngosipụta nke ọrịa shuga mellitus na-arịa, na iji hydrochlorothiazide na usoro ọgwụgwọ dị elu - mmụba nke mkpokọta lipids n'ọbara ọbara,
• sitere na akwara gbasara obi: odi - orthostatic hypotension, bradycardia, vasculitis,
• site na usoro akwara: ike adịghị ike,
• site na akụkụ ahụ haemopoietic: dịkarịsịrị ike - hemolytic / aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia,
• site na nri digestive: adịkarịghị - sialadenitis, afọ ọsịsa, afọ ntachi, ọgbụgbọ, vomiting, anorexia, cholestatic jaundice, pancreatitis, cholecystitis,
• sitere na ụjọ na akwara anụ ahụ: ọ na - adịkarịghị - ọhụụ na - adịchaghị mma, ọgụ dị egwu nke glaucoma nnukwu, myopia, isi ọwụwa, isi ọwụwa, mgbakasị ahụ, paresthesia,
• mmeghachi omume hypersensitivity: na - adịkarịghị - fotoensitivity, purpura, akpịrị anụ ahụ, itching, urticaria, necrotizing vasculitis, Stevens-Johnson syndrome, mmeghachi omume anaphylactic ruo ujo, ọrịa mgbu iku ume (gụnyere pneumonitis na ọrịa obi na-abụghị cardiogenic)
• ndị ọzọ: iwe iwe nke sistemu lupus erythematosus, nephritis interstitial, ọrụ ezughi oke, belata ikike.

Ọnụahịa dị na ahịa ọgwụ

Ọnụ ego hydrochlorothiazide maka ngwugwu 1 sitere na 50 rubles.

Nkọwa dị na ibe a bụ ụdị dị mfe nke nkọwapụta ọgwụ ọgwụ. Enyere ozi a maka ebumnuche gbasara ọfụma ọ bụghị ntuziaka maka ọgwụ ịchọrọ onwe gị. Tupu ị usingụ ọgwụ ahụ, ị ​​ga-agakwuru onye ọkachamara ma mara onwe gị na ntuziaka nke onye nrụpụta kwadoro.

Usoro onunu ogwu na nhazi

Iji wedata ọbara mgbali elu: site n’ọnụ, 25-50 mg / ụbọchị, ebe a na-ahụ ntakịrị diuresis na natriuresis naanị n’ụbọchị mbụ nke nchịkwa (enyere iwu ka ọ dị ogologo oge na ọgwụ ndị ọzọ antihypertensive: vasodilators, angiotensin-converting inhibitors, ọmịiko, beta-blockers). Site na mmụba nke dose site na 25 ruo 100 mg, a na-achọpụta mmụba nke diuresis, natriuresis na mbelata ọbara mgbali. N'ime otu ụdị ihe karịrị 100 mg, a na-achọpụta mmụba nke diuresis na mbelata ọbara mgbali elu adịghị mkpa, a na-ahụkarị ọnwụ electrolytes, ọkachasị potassium na magnesium ion. Asingbawanye ọgwụ karịrị 200 mg abụghị ihe arụ, n'ihi na ụba diureis anaghị eme.

Na ọrịa edematous (dabere na ọnọdụ na mmeghachi omume nke onye ọrịa) ka etinyere na ọgwụ kwa ụbọchị nke 25-100 mg, ewere otu ugboro (n'ụtụtụ) ma ọ bụ na usoro 2 (n'ụtụtụ) ma ọ bụ 1 oge na ụbọchị 2.

Ndị okenye - 12.5 mg 1 - ugboro 2 n'ụbọchị.

Maka umuaka mgbe ọ dị afọ atọ ruo afọ iri na anọ - 1 mg / kg / ụbọchị.

Mgbe ọ gwọchara ụbọchị atọ ruo ise, a na-atụ aro ka ya ezumike ruo ụbọchị 3 ruo ise. Dika usoro nlekọta mmezi na onodu ekwesiri ka aghọrọ ọgwụ ugboro abụọ n'izu. Mgbe ị na-eji usoro ọgwụgwọ dị iche iche na nchịkwa mgbe ụbọchị 1 ruo 3 ma ọ bụ n'ime ụbọchị 2 ruo atọ, nke na-esochi izu ike, mbelata nke ịdị irè agaghị ekwusi ike na nsonaazụ ya anaghị apụta obere oge.

Iji belata nrụgide intraocular Ejiri 25 mg otu ugboro kwa ụbọchị ruo ụbọchị isii, mmetụta ahụ na-apụta mgbe awa 24 - 48 gachara.

Na ọrịa shuga insipidus - 25 mg 1 - ugboro 2 kwa ụbọchị na mmụba nwayọ nwayọ na dose (kwa ụbọchị - 100 mg) ruo mgbe a ga-enweta nsonaazụ ọgwụgwọ (belata na akpịrị ịkpọ nkụ na polyuria), mbelata ọzọ ọgwụ ga-ekwe omume.

Njirimara ngwa

Site na ọgwụgwọ ogologo oge, ọ dị mkpa iji nlezianya nyochaa ihe ngosipụta ahụike nke nrụgide mmiri-electrolyte, nke mbụ na ndị ọrịa nọ n'ihe ize ndụ dị elu: ndị ọrịa nwere ọrịa obi na sistem imeju.

A ga-ezere Hypokalemia site na iji ọgwụ ndị nwere potassium ma ọ bụ nri bara ụba na K + (potassium), mkpụrụ osisi, karịchaa ụkọ K + (mmụba dị ukwuu, ọgwụgwọ ogologo oge) ma ọ bụ ọgwụgwọ n'otu oge na cardiac glycosides ma ọ bụ glucocorticosteroids.

Ọ na - eme ka amịnesia magnesium dị na mmamịrị ya, nke nwere ike ibute hypomagnesemia.

Na ọdịda akụrụngwa akwara na-adịghị ala ala (CRF), ọ dị mkpa ileba anya mgbe niile na iwepụta ihe iji mee ka ihe dị mma (CC). Na ọdịda akụrụngwa na-adịghị ala ala, ọgwụ nwere ike ịnakọta ma kpatara mmepe nke azotemia. Site na mmepe nke oliguria, enwere ike ịtụle ohere nke ịhapụ ọgwụ.

N'ọnọdụ dị njọ ma na-agbatị umeji na-agafe agafe ma ọ bụ ọrịa imeju na-aga n'ihu, a na-eji ọgwụ elebara ọgwụ anya, ebe ọ bụ na obere mgbanwe na mmiri-electrolyte itule na mkpokọta amonia na serum nwere ike ibute ọrịa ịba ọcha n'anya.

N'ihe banyere akụkụ ụbụrụ na ọnya na-akpata oke ala, iji ọgwụ a chọrọ nlekọta pụrụ iche.

Nwere ike imebi nnabata glucose. N'ime ogologo oge ọgwụgwọ maka ọrịa mellitus na-arịa ọrịa shuga na shuga, ọ kwesịrị ịdị mkpa iji nyochaa metabolism metabolism; ịhazigharị ọgwụ hypoglycemic ọgwụ. N'oge ọgwụgwọ, ọ dị mkpa itinye uche ugboro ugboro banyere itinye uric acid.

Site na usoro ọgwụgwọ ogologo oge, n'ọnọdụ ndị a na-adịghị ahụkebe, a chọpụtara mgbanwe ọrịa na arụ ọrụ nke glands parathyroid, yana hypercalcemia na hypophosphatemia. O nwere ike imetụta nsonaazụ nyocha nke ụlọ nyocha nke ọrụ parathyroid, yabụ, tupu ikpebie ọrụ nke glands parathyroid, ọgwụ ahụ kwesịrị ịkwụsị.

Hydrochlorothiazide nwere ike belata ego nke ayodiin jikọtara protein na-enweghị ihe ngosi nke ọrụ thyroid na-arụ ọrụ.

N'ime mmalite ọgwụ iji ọgwụ ọjọọ eme ihe (a na-ekpebi oge a n'otu n'otu), a na-atụ aro ka ọ kwụsị ịkwọ ụgbọala na ịrụ ọrụ na-achọ ịbawanye ụba nke nlebara anya na ọsọ nke mmeghachi omume psychomotor (n'ihi mmepe nke nkụda mmụọ na ụra.

Ngwá ọgwụ ọgwụ

Mbadamba Hydrochlorothiazide bụ thiazide diuretics. Ihe dị n'ime ọgwụ ahụ na - akpaghasị nnweta nke sodium, mmiri na ion chlorine na akụkụ ndị dị anya nke akụrụ real, ma na - akwalite uto nke potassium na ion magnesium.

Mmetụta ọgwụgwọ kachasị kacha elu na-etolite awa 2 mgbe ị takingụ ọgwụ ọ bụla.

N'ihi iwepu mmiri dị ukwuu n'ahụ ahụ, ihe na-arụ ọrụ nke diuretic ahụ na-enyere aka belata ọbara mgbali elu, belata edema, belata polyuria na ndị ọrịa nwere ọrịa insipidus.

Ojiji nke ogwu n’oge di ime na inye ndi ara ara

A machibidoro iji hydrochlorothiazide mbadamba n'ime oge atọ nke afọ ime, ebe ọ bụ na n’oge a, ịkpụpụta akụkụ nke akụkụ nwa ebu n'afọ na sistem, ọgwụ nwere ike kpaghasị usoro a.

Ojiji nke ogwu n'ime oge nke abụọ na nke atọ nke afọ ime ga - ekwe omume naanị mgbe nyochachara nke ọma banyere ndị na - egosi uru / ihe ize ndụ yana n'okpuru nlekọta dọkịta.

Amachibidoro iji ọgwụ eme ihe n’oge a na-enye nwa ara, ebe ọ bụ na ihe ndị dị n’ọrụ nke ọgwụ ahụ nwere ike ịbanye n’ime mmiri ara, wee banye n’ime nri nwata. Ọ bụrụ na ọgwụgwọ hydrochlorothiazide dị mkpa, a ga-akwụsị ịhapụ mmiri ọkụ!

Nsonaazụ

N'iji ọgwụ mee ihe n'ụzọ ziri ezi, nsonaazụ ya na-apụta naanị n'ọnọdụ ndị a na-adịghị ahụkebe. Ọ bụrụ n ’ịnwere ike karịa iji ọgwụ enyere gị aka ma ọ bụ iji ọgwụ a na-achịkwaghị achịkwa ruo ogologo oge, ọnọdụ ndị a nwere ike ịmalite na ndị ọrịa:

• Ọrịa digestive: mbufụt nri, cholecystitis, nsogbu ọnya, enweghị agụụ, jaundice, mgbu nke imeju,
• Ahụhụ anya
• Dizzness ma ọ bụ isi ọwụwa,
• Mmetụta nke "ịgba" na anụ ahụ,
• Mmepe nke vasculitis, anaemia, leukopenia, hyponatremia,
• Mkpesa megide nzụlite nke imebi nguzozi-nnu n’ime ahụ,
• Mgbakasị ma ọ bụ ịba ụba oke iwe
• Thirstba ụba akpịrị ịkpọ nkụ, akpịrị kpọrọ nkụ,
• Ogbugbu na gagging
• Uto adịghị ike ma ọ bụ nkụda mmụọ,
• Ọrịa akpụkpọ ahụ Allergic - urticaria, angioedema, rashes,
• Akwara mgbu
• Imebi akụrụ na imeju, n'ọnọdụ ndị siri ike, mmepe nke imeju etolite ruo coma.

Mmekọrịta nke ọgwụ ya na ọgwụ ndị ọzọ

Iji otu mbadamba ọgwụ hydrochlorothiazide na ọgwụ mgbochi mkpali na-abụghị steroidal ma ọ bụ anticoagulants na-apụtakarị, a na-eme ka mmetụta ọgwụgwọ nke diuretic ahụ dị, nke ekwesiri iburu n'uche mgbe ị na-ede ọgwụ ahụ.

Ojiji nke ọgwụ a n’otu oge na antidepressants, barbiturates, ma ọ bụ ethanol, enwere mmụba na mmetụta ya.

Ihe na - arụ ọrụ nke hydrochlorothiazide na - ebelata ọgwụ mgbochi ọgwụ a na - egbochi ọgwụ iji gbochie afọ ime, nke ekwesịrị ịdọ ndị ọrịa aka na ntị karịa ụdị ịtụrụ ime na - achọghị ịtụrụ ime.

Mbadamba ala diuretic, ọkachasị hydrochlorothiazide, na-amụba ohere nke mmetụta ndị ọzọ mgbe a na-agwọ ya na glycosides cardiac.

Ọnọdụ nke ọgwụ na ịchekwa ọgwụ

A na-enye mbadamba osisi Hydrochlorothiazide n'ụlọ ahịa ọgwụ n'enyeghị ọgwụ dọkịta. Ekwesịrị ịchekwa ọgwụ ahụ site na iru ụmụaka agaghị enweta ogo 20. Ndụ nchekwa nke mbadamba bụ afọ abụọ site na ụbọchị a rụpụtara.

Onu ego nke ọgwụ Hydrochlorothiazide n'ụdị mbadamba ihe dị na ụlọ ahịa ọgwụ na Moscow bụ 60-70 rubles.