Insulin Actrapid: ọnụ ahịa na ntuziaka maka ojiji

Traditionzọ ọdịnala iji belata shuga mgbe ị risịrị nri gụnyere insulins mmadụ na-eme mkpụmkpụ. Otu n'ime ọgwụ ndị kachasị ewu ewu, Actrapid, na-alụ ọgụ ọrịa shuga kemgbe ihe karịrị afọ iri atọ. N'ime ọtụtụ afọ, ọ gosipụtala ezigbo mma ya ma zọpụta ọtụtụ nde ndụ.

Ka ọ dị ugbu a, insulins ọhụụ dị ugbua adịlarị na -emepụta glycemia nkịtị ma nwekwa nsogbu site na ndị bu ha ụzọ. N'agbanyeghi nke a, Actrapid anaghị ada mba ọ nọ ma jiri ya rụọ ọrụ na ọgwụgwọ nke ọrịa shuga 1 na ụdị nke 2.

Ntụziaka dị mkpirikpi maka ojiji

Actrapid bụ otu n'ime ihe mbụ ebupụtara site na usoro inyocha mkpụrụ ndụ ihe nketa. Emepụtara ya na 1982 bụ ọgwụ ọgwụ Novo Nordisk, otu n'ime ndị kachasị mmepe nke ọgwụ shuga n'ụwa. N'oge ahụ, ndị ọrịa mamịrị nwere afọ ojuju na insulin anụmanụ, nke nwere ntakịrị mmacha yana oke allergenicity.

A na - enweta ọgwụ eji eme ihe site na iji ọgwụ nje emegharị, ngwaahịa a rụchara arụpụtaghachi kpamkpam insulin emepụtara n'ime mmadụ. Teknụzụ mmepụta ahụ na-enye aka nweta ezigbo hypoglycemic mmetụta na ịdị ọcha dị elu nke ihe ngwọta, nke belatara ihe ize ndụ nke allergies na mkpali na ntanetị. Rada (edebanye aha ọgwụ nke Ministrylọ Ọrụ Ahụike debara aha) na-egosi na enwere ike ịhazi ọgwụ ahụ ma kee ya na Denmark, France na Brazil. A na-achịkwa njikwa mmepụta naanị na Europe, ya mere, enweghị mgbagha dị ka ọgwụ.

Ozi dị mkpirikpi banyere Actrapide site na ntuziaka maka ojiji nke ọrịa shuga ọ bụla kwesịrị ịmara:

Ọ bụrụ n ’usoro a gafere gabiga ya, hypoglycemia na - apụta, nke nwere ike ibute coma n’ime otu elekere. Udiri shuga na -emekarị ugboro ugboro na-emebi mmebi akwara, na-ewepụ ihe mgbaàmà hypoglycemia, nke na-eme ka o sie ike ịchọpụta.

N'ọnọdụ nke imebi usoro nke ịgba ọgwụ insulin Actrapid ma ọ bụ n'ihi njirimara nke ọkpọ anụ ahụ, lipodystrophy ga-ekwe omume, ugboro ole ha na-erughị 1%.

Dịka ntuziaka ahụ si dị, mgbe ị na-agbanwe insulin na ọdịda shuga ngwa ngwa, mmeghachi omume n'akụkụ oge ga-ekwe omume na-apụ n'anya nke onwe ha: ọhụhụ anya, ọzịza, neuropathy.

Insulin bụ nkwadebe siri ike, n'otu sirinji enwere ike ịgwakọta ya naanị na nnu si na insulins ndị na-ajụ, ka nke otu emeputa (Protafan). Ọ dị mkpa ka ndị insulin na - arịa insulin na - arịa ọrịa shuga nke nwere ọgụgụ isi dị ukwuu na homonụ, dịka ọmụmaatụ, ụmụaka. Ejikọtara ya na ọgwụ ndị na-eme ihe maka ụdị shuga 2, na-abụkarị ndị agadi.

Drugs drugsụ ọgwụ ụfọdụ n’otu oge nwere ike metụta ọrụ insulin. Hormonal na diuretics nwere ike ịkụda nsonaazụ nke Actrapid, yana ọgwụ ọgbara ọhụrụ maka nrụgide na ọbụna tetracycline nwere ọgwụ aspirin nwere ike iwusi ya ike. Ndị ọrịa na ọgwụ insulin kwesịrị iji nlezianya mụọ ngalaba “Nmekorita” na ntuziaka nke ọgwụ niile ha na-eme atụmatụ iji. Ọ bụrụ na ọgwụ a nwere ike imetụta ihe insulin na-eme, a ga-agbanwe usoro onodu ogwu nke Actrapid nwa oge.

A na - etinye ọgwụ Actrapid kwa afọ na ndepụta ọgwụ ndị dị mkpa, yabụ ndị ọrịa mamịrị nwere ike nweta ya n'efu, na ndenye dọkịta gị.

Ozi ndi ozo

Actrapid NM na-ezo aka na mkpụmkpụ (ndepụta nke insulins dị mkpụmkpụ), mana ọ bụghị ọgwụ ultrashort. Ọ na-amalite ime ihe mgbe nkeji iri atọ gasịrị, yabụ ha na-ewebata ya tupu oge eruo. Ọrịa glucose sitere na nri nwere GI dị ala (dịka ọmụmaatụ, buckwheat na anụ) na-ejide “ijide” insulin a ma wepụ ya n'ọbara n'oge oge. Site na ngwa ngwa carbohydrates ngwa ngwa (dịka ọmụmaatụ, tii na achicha), Actrapid enweghị ike ịlụ ọgụ ngwa ngwa, yabụ mgbe ị eatingụ hyperglycemia ga-emerịrị, nke ga-eji nwayọ belata. Ọ bụghị nanị na ụdị shuga dị otú a na-eme ka ọdịmma onye ọrịa ka njọ, kamakwa ọ na-eme ka ọganihu nke ọrịa shuga na-akpata. Iji belata uto nke glycemia, nri ọ bụla nwere insulin Actrapid kwesịrị inwe eriri, protein ma ọ bụ abụba.

Oge ọrụ

Actrapid na-arụ ọrụ ruo elekere asatọ. Oge awa ise mbụ - ihe bụ isi, emesia - ngosipụta ndị ọzọ. Ọ bụrụ na a na-ahụ insulin ugboro ugboro, nsonaazụ nke doses abụọ ga-ejikọ ibe ha. N'otu oge ahụ, ọ fọrọ nke nta ka ọ bụrụ ihe siri ike ịgụta usoro ị theụ ọgwụ a chọrọ, nke na-abawanye ihe ize ndụ nke hypoglycemia. Iji were ọgwụ ọfụma na-eme nke ọma, ọ dị mkpa ka ekesaa nri na inje inulin ọ bụla kwa awa 5.

Ọgwụ ahụ nwere oke arụmọrụ mgbe awa 1.5-3.5 gachara. N'oge a, ọtụtụ nri nwere oge mgbari, yabụ hypoglycemia na-apụta. Iji zere ya, ịchọrọ nri maka 1-2 XE. Na mkpokọta, na-arịa ọrịa shuga mellitus kwa ụbọchị, a na-enweta 3 isi na nri 3 ọzọ.A na-ahụ maka insulin Actrapid naanị tupu ndị bụ isi, mana a na-agbakọ ọnụọgụ ya na-eburu n'uche nri.

Iwu mmeghe

Enwere ike iji vials nwere Actrapid NM nwere ike iji sirinji insulin kpọrọ akara U-100. Cartridges - ya na ogwe osisi sirinji na pensụl: NovoPen 4 (usoro onunu ogwu 1 nkeji), NovoPen Echo (0,5 nkeji).

Iji mee ka insulin rụọ ọrụ nke ọma na ọrịa shuga, ịkwesịrị ịmụ usoro ntụtụ na ntuziaka maka ojiji ma soro ya. Ọtụtụ mgbe, a na-agbanye Actrapid n'ime mmanu na afọ, a na-etinye sirinji n'akụkụ akụkụ ahụ. Mgbe itinyechara ya, anaghị ewepụ agịga ahụ ruo ọtụtụ sekọnd iji gbochie ngwọta ahụ ịpụta. Insulin kwesịrị ịdị n ’ọnọdụ ụlọ. Tupu nchịkwa, ọ dị mkpa ịlele ụbọchị ngafe na ọdịdị nke ọgwụ.

A machibidoro karama nwere ọka, sedimenti ma ọ bụ kristal n’ime ime.

Tụnyere ihe ndị ọzọ insulins

N'agbanyeghị eziokwu ahụ bụ na mora Actrapid dị na insulin mmadụ, mmetụta ha dị iche. Nke a bụ n'ihi nchịkwa ọgwụ subcutaneous. Ọ chọrọ oge iji hapụ anụ abụba wee mepụta ọbara. Na mgbakwunye, insulin na-adịkarịzi ike n’inwe usoro dị omimi n’ime akwara, nke na-egbochikwa mbelata shuga ngwa ngwa.

Dọkịta nke Sciences Medical, Isi nke Institute of Diabetology - Tatyana Yakovleva

Agụọla m ọrịa shuga kemgbe ọtụtụ afọ. Ọ na-atụ ụjọ mgbe ọtụtụ mmadụ nwụrụ, nweekwa nkwarụ karịa n'ihi ọrịa shuga.

Emere m ngwa ngwa izisa ozi ọma - Endocrinological Research Center nke Russian Academy of Medical Sciences jikwaa aka ịmalite ọgwụ na-agwọ ọrịa shuga mellitus kpamkpam. N'oge a, ịdị irè nke ọgwụ a na-eru nso 98%.

Ozi ọma ọzọ: Ministri Ahụike echekwaala maka mmemme pụrụ iche nke na-akwụ ụgwọ ọgwụ dị elu. Na Russia, ndị ọrịa mamịrị ruo Mee Mee 18 (isonye) nwere ike inweta ya - Naanị 147 rubles!

A na - anapụ ndị insidins ndị ọhụrụ ultrashort - Humalog, NovoRapid na Apidra - adịghị ike ndị a. Ha na-amalite ịrụ ọrụ na mbụ, yabụ ha na-ejikwa wepu carbohydrates ngwa ngwa. Oge ha na-ebelata, ọ nweghịkwa ọnụ ọgụgụ kacha elu, ya mere nri nwere ike ịdị ọtụtụ ugboro, nri adịghị mkpa. Dabere na ọmụmụ, ọgwụ ultrashort na-enye njikwa glycemic ka mma karịa Actrapid.

Uzo eji insul na-eme insulin maka oria shuga nwere ike ikwenye ekwenye:

• n'ime ndị ọrịa na-agbasosi obere nri carb, ọkachasị na ụdị shuga 2,
• n'ime ụmụ nke na-eri nri kwa awa 3.

Ego ole bụ ọgwụ ahụ? Uru ndị a na-ejighị n’aka nke insulin a bụ obere ọnụahịa ya: otu 1 nke Actrapid na-akwụ 40 kopecks (400 rubles kwa karama 10 ml), homonụ ultrashort - ugboro atọ karịa ọnụ.

Nkwadebe insulin na-eme mmadụ nwere ihe dị na ndụ otu na ihe ndị ọzọ yiri ya:

Mgbanwe site na insulin gaa na nke ọzọ ga-eme naanị n'ihi ihe gbasara ahụike, ebe ọ bụ na akwụ ụgwọ nke ọrịa shuga ga-emerịrị njọ n'oge nhọrọ nke usoro ị ofụ ọgwụ.

Jikere muta! You chere na nchịkwa ọgwụ ogologo oge na ọgwụ bụ naanị ụzọ eji egbochi shuga? Ọ bụghị eziokwu! Nwere ike ịchọpụta nke a n'onwe gị site na ịmalite iji ya. gụkwuo >>

Pharmacodynamics na pharmacokinetics

Insulin insulin mepụtara site na iji mmiri ọgwụ nje mee ihe ọzọ Saccharomyces cerevisiae. Ya INN bu - Insulin mmadụ.

Ọgwụ ahụ na-eso onye na-anabata ihe mejupụtara mkpụrụ ndụ nke cytoplasmic nke mkpụrụ ndụ. Ọ na-etolite ogige nnabata insulin. Ọ na - eme ka usoro intracellular rụọ ọrụ site na - akpali biosynthesis. cAMP ma ọ bụ site na ịbanye na akwara akwara.

Mbelata nke ọkwa glucose bụ n'ihi ụba njem na nnabata intracellular site na anụ ahụ, ịgbalite lipogenesisnjikọ protein na glycogenogenesis, yana mbelata ọnụego mgbụpụta glucose site na imeju, wdg.

Ihe ị ofụ ọgwụ ahụ na-amalite n'ime nkeji iri atọ mgbe etinyere ngwa. A na-ahụkarị mmetụta kachasị na nkezi n'ime elekere 2.5. Oge ngụkọta oge a na-eme ihe ruru awa 7-8.

Atụmatụ nke onwe maka ndị ọrịa ga-ekwe omume, gụnyere ndị dabere n ’ụzọ ọ dị.

Ntụziaka maka iji Actrapid (Usoro na usoro onunu ogwu)

Ntuziaka maka Actrapid na-akọ na a na-achịkwa ọgwụ ahụ subcutaneously ma ọ bụ intravenously. A na-ahọrọ usoro ọgwụgwọ ahụ site n'aka ndị ọkachamara n'otu n'otu, dabere na mkpa nke onye ọrịa. insulin. Dịka iwu, usoro ịse ya bụ 0.3-1 IU / kg kwa ụbọchị. Na nguzogide insulinchoro nwere ike idi elu, ma n'ihe banyere olulu mmepụta insulin na-agwụ ike - n'okpuru. Ndị ọrịa kwesịrị iji nlezianya nyochaa glucose ha ọbara.

Bụrụ na nsogbu ndị gbasara akụrụngwa ma ọ bụ ọrụ ịba ọcha n'anya insulinbelata. Ya mere, ịkwesịrị idozi usoro ọgwụgwọ.

Ntuziaka maka iji Actrapid na-egosi na enwere ike iji ya na yana ogologo eme insulins.

A na-enye ọgwụ ahụ ọkara ọkara tupu nri ma ọ bụ nri nwere carbohydrates. Dịka iwu, a na-eme inje subcutaneously na mpaghara nke akụkụ ihu ime. Nke a na-enye nnabata ngwa ngwa. Na mgbakwunye, enwere ike ịme ntanetị n'apata ụkwụ, akwara deltoid nke ubu ma ọ bụ buttock. Iji gbochie lipodystrophyỌ dị mkpa ịgbanwe saịtị ndị gbanye mmadụ.

Nchịkwaa nke intraven ka nwere ike ikwe naanị ma ọ bụrụ na ndị ọkachamara n ’ọgwụ. N'ime intramuscular, a na-enye ọgwụ ahụ naanị ka onye ọkachamara nyere ya ndụmọdụ.

Dodoụbiga ya ókè

Yabụ ị anụbiga mmanya ókè, ihe ndị a ga-ekwe omume: ehighi uraoke pallor, mmụba na-abawanye na agụụ, ịma jijiji, ọsụsọ, isi ọwụwa, paresthesia n'ọnụ, palpitations. N'ihe banyere iji ọgwụ eme ihe na ọgwụ onunu ogwu gabigara oke iwu, onye ọrịa nwere ike ịdaba onye ka.

Bụrụ na ìhè hypoglycemiasugar ga-eri shuga ma ọ bụ nri nwere nnukwu shuga. N'ime ịdoụbiga mmanya ókè, a na-edozi 1 mg intramuscularly Glucagon. Ọ bụrụ na ọ dị mkpa, a na-agbakwunye ngwakọta glucose ike.

Mmekorita

Mmetụta hypoglycemic insulinna-abawanye mgbe ewere ya ndị na-arịa ọrịa hypoglycemic nke ọnụ, angiotensin na - agbanwe enzyme inhibitors, ndị na - abụghị ndị na - eme nhọrọ beta, sulfonamides, tetracycline, Ketoconazole, Pyridoxine, cyclophosphamidenkwadebe lithium ndị na-egbochi monoamine oxidase na carbonic anhydrase, Bromocriptine, anabolic steroid, Clofibrate, Mebendazole, Theophylline, Fenfluramine na ogwu nwere ethanol. Ọ bụghị nanị na mmanya na-egbu egbu na-eme ka ọ dịkwuo mma, mana ọ na-agbatịkwu mmetụta nke Actrapid.

Mmetụta hypoglycemic, na ntụle, na-agbada n'okpuru nduzi nke ogwu gboro ya, homonụ thyroid, Heparina, nnabata ọmiko, Clonidine, Diazoxide, Phenytoin, glucocorticosteroids, thiazide diuretics, tricyclic antidepressantsn'ime, Danazole, ihe mgbochi calcium, morphine, nikotin.

Nsonaazụ nke Actrapid nwere ike bulie ma ọ bụ ibelata n'ihi ojiji Ihe ndozi na salicylates. Octreotide, Lanreotide nwere ike belata ma ọ bụ nwekwuo mkpa maka insulin.

N'ikuku ihe mgbochi beta nwere ike zoo ihe mgbaàmà hypoglycemia ma gbochie ikpochapu ya.

Productsfọdụ ngwaahịa, dịka ọmụmaatụ, nwere thiolsma obu sulfitesnwere ike ịkpata mbibi insulin.

Exbọchị mmebi

A na-echekwa karama emepe ihe ọ bụla karịa izu isii. Tupu ịmalite, ndụ nchekwa nke ọgwụ bụ ọnwa 30. Ejila ihe osisa nye ya mgbe emechara ya.

Nyocha na-akọwa Actrapid dị ka ọgwụ a pụrụ ịdabere na ya nke na-enye gị ohere ịnweta njikwa amụma glycemia. Ndị ọrịa na-enwe ike ị likeụ ọgwụ ọsọ. N'etiti akụkụ ndị na-adịghị mma, ọ bụ naanị ụdị ịtọhapụ ọgwụ ọjọọ n'ụdị ihe ngwọta maka ogwu ogbugba, ntinye nke a na-achọkarị nlekọta ọkachamara.

Ọnụahịa efu, ebe ịzụta

Ọnụahịa Actrapida ihe dịka 450 rubles. Nwere ike ịzụta ngwa ọrụ a naanị site na ndenye ọgwụ.

Ọnụahịa Insulin Actrapid HM Penfill bụ ihe dịka 950 rubles. N'ihi ya, a na-ewere ọgwụ dị oke ọnụ. Somefọdụ ụlọ ahịa ọgwụ dị n'ịntanetị, ọnụahịa nke Actrapid nwere ike ịdị elu karịa ka egosipụtara.

Ngwakọta na ụdị ntọhapụ

Ngwọta maka ntụtụ - 1 ml:

• bekee na-arụ ọrụ: insulin soluble sistemụ mmadụ - 100 IU (3.5 mg), 1 IU kwekọrọ na 0.035 mg nke insulin mmadụ na-arụ ọrụ,
• ndị na - ahụkarị: zinc chloride, glycerin (glycerol), metacresol, sodium hydroxide na / ma ọ bụ hydrochloric acid (iji dozie pH), mmiri maka injection.

10 ml n'ime karama iko, jiri roba teepu na okpu plastic, jiri karama 1 karama.

Ngwọta nke nsị ahụ doro anya, enweghị agba.

Insulin na-eme ka mmadụ dị mkpụmkpụ.

Nnukwu insulin nke mmadụ na-eme n’onwe ya. Ọ bụ insulin nke oge ihe ji arụ ọrụ. Na -emezi usoro glucose, nwere mmetụta anabolic. Na akwara na akwara ndị ọzọ (ewezuga ụbụrụ), insulin na - eme ka glucose na amino acids nwee intracellular intracellular. Insulin na - akwalite ntụgharị nke glucose na glycogen na imeju, na - egbochi gluconeogenesis ma na - akpali ntụgharị nke oke glucose na abụba.

Ngwọta nm Jiri ime na ụmụaka

N’ime afọ ime, ọ dị mkpa ijide njiri glycemic nke ọma n’ime ndị ọrịa nwere ọrịa shuga. N'oge afọ ime, mkpa nke insulin na-ebelata na ọkara nke mbụ ma na-abawanye na nke abụọ na nke atọ.

A na-atụ aro ka ndị ọrịa na-arịa ọrịa shuga mellitus gwa dọkịta banyere mmalite ma ọ bụ atụmatụ nke ịtụrụ ime.

N'ime ndị ọrịa nwere ọrịa mellitus n'oge a na-enye nwa ara (inye nwa ara), enwere ike ịchọ mgbanwe insulin, nri, ma ọ bụ ha abụọ.

Na nyocha nke nsen mkpụrụ ndụ ihe ọmụmụ na in vitro na usoro vivo, insulin mmadụ enweghị mmetụta nke mutagenic.

Nsonaazụ nm

Site na usoro endocrine: hypoglycemia.

Ọrịa hypoglycemia siri ike nwere ike ibute ọnwụ na (n'ọnọdụ ụfọdụ) ọnwụ.

Mmeghachi omume nfụkasị: mmeghachi omume nfụkasị mpaghara enwere ike - hyperemia, ọzịza ma ọ bụ itching na saịtị ịgba ahụ (na - akwụsịkarị n'ime oge ọtụtụ ụbọchị ruo ọtụtụ izu), mmeghachi omume nfụkasị usoro (na - erughị oge, mana ọ ka njọ) - itching juputara, mkpụmkpụ ume, mkpụmkpụ ume , mgbada ọbara na-ebelata, obi mgbali elu, ịba ụba aja. Ọnọdụ siri ike nke mmeghachi omume nfụkasị systemic nwere ike igbu mmadụ.

A na-ebelata hypoglycemic mmetụta site na mgbochi nke ọnụ, corticosteroids, nkwadebe homonụ thyroid, thiazide diuretics, diazoxide, antidepressants tricyclic.

A na - eme ka mmetụta hypoglycemic dị elu site na ọgwụ ọgwụ hypoglycemic, salicylates (dịka ọmụmaatụ acetylsalicylic acid), sulfonamides, MA inhibitors, beta-blockers, ethanol na ọgwụ ethanol nwere.

Beta-mgbochi, clonidine, reserpine nwere ike kpuchie ngosipụta nke ọrịa hypoglycemia.

Dosage Actrapid nm

P / c, n'ime / n'ime. A na-ahọrọ ọ̀gwụ nke ọgwụ n’otu n’otu n’ileba anya na mkpa onye ọrịa. Dị ka ọ dị, mkpa onye insulin nwere ọrịa sitere na 0.3 ruo 1 IU / kg / ụbọchị. Ihe a chọrọ kwa ụbọchị maka insulin nwere ike ịdị elu karịa n’ebe ndị ọrịa na - eguzogide insulin (dịka ọmụmaatụ, n’oge uto, yana n’ime ndị ọrịa bu oke ibu) ma belata obere n’ime ndị ọrịa n’onwe ha imepụta insulin.Ọ bụrụ na ndị ọrịa na-arịa ọrịa shuga na-enweta njikwa glycemic kachasị mma, mgbe ahụ nsogbu ndị na-arịa ọrịa shuga na ha, dịka iwu, ga-apụta mgbe e mesịrị. N'akụkụ a, mmadụ kwesịrị ịgbalịsi ike ịkwalite njikwa metabolic, karịchaa, site n'iji nlezianya nyochaa ọkwa nke glucose dị n'ọbara.

Actrapid ® NM bụ insulin na-adị mkpụmkpụ ma enwere ike iji ya na insulins dị ogologo.

A na-enye ọgwụ ahụ nkeji iri atọ tupu nri ma ọ bụ nri nwere carbohydrates. A na-ahụkarị Ntanakiri ra NM ka ọ bụrụ mpaghara nke mgbidi akụkụ ihu. Ọ bụrụ na nke a dabara adaba, enwere ike ịme injections n'apata ụkwụ, mpaghara gluteal ma ọ bụ mpaghara akwara dị n'ubu. Site na ntinye ọgwụ a na mpaghara mpaghara mgbidi afọ, a na-enweta mmịpụ ngwa ngwa karịa iwebata ya na mpaghara ndị ọzọ. Perrụpụta ntụtụ n’akpụkpọ ahụ na-ebelata ohere ịbanye n’olu.

Ọ dị mkpa ịgbanwe ebe a na-agba agba gburugburu mpaghara anatomical iji gbochie mmepe nke lipodystrophy.

Ọ ga-ekwe omume inje intramuscular, ma ọ bụ naanị dị ka dọkịta si nye gị.

Actrapid ® NM nwekwara ike ịbanye / nbanye, usoro ndị ọkachamara ahụike nwere ike ịme ya.

N'ihi mmerụ akụrụ ma ọ bụ imeju, a na-ebelata mkpa insulin na-ebelata.

Ntugharị onye ọrịa na ụdị insulin ọzọ ma ọ bụ ịkwado insulin nwere aha azụmaahịa dị iche iche kwesịrị ịmalite n'okpuru nlekọta ahụike siri ike.

Mgbanwe na arụ ọrụ insulin, ụdị ya, ụdị (anụ ezi, insulin mmadụ, anaulin insulin) ma ọ bụ usoro mmepụta (insulin nke insulin ma ọ bụ insulin nke sitere anụmanụ) nwere ike ime ka edozigharị dose.

Enwere ike ịchọ mgbanwe mmezi onodu na nhazi mbụ nke nkwalite insulin mgbe nkwadebe insulin sitere na anụmanụ ma ọ bụ jiri nwayọ gafee ọtụtụ izu ma ọ bụ ọnwa mgbe nnyefe ahụ gasịrị.

Mkpa insulin nwere ike wedata na arụmọrụ adrenal ezughi ezu, pituitary ma ọ bụ thyroid gland, yana akụrụ gbasara akwara ma ọ bụ mmebi.

Somenwe ọrịa ụfọdụ ma ọ bụ nrụgide mmetụta uche, ịchọrọ insulin nwere ike ịba ụba.

Ọ nwekwara ike ịdị mkpa iji dozigharị azụ mgbe ị na-eme ka ahụ dịkwuo gị mma ma ọ bụ mgbe ị na-agbanwe nri ị na-eri.

Udiri oria ndi choro hypoglycemia n'oge ochichi nke insulin n’ime mmadu n’enweghi ike ikwuputa ma obu di iche na ndi ahutara n’oge ochichi insulin. Site na nhazi nke ọkwa glucose ọbara dị ka ọmụmaatụ, n'ihi ọgwụgwọ insulin kpụ ọkụ n'ọnụ, ihe niile ma ọ bụ ụfọdụ ihe mgbaàmà nke ihe ịrịba ama nke hypoglycemia nwere ike ịkwụsị, gbasara nke e kwesịrị ịgwa ndị ọrịa.

Mgbaàmà nke hypoglycemia nke hypoglycemia nwere ike gbanwee ma ọ bụ belata ka ọ dị ogologo oge na ọrịa mellitus, ọrịa mamịrị, ma ọ bụ iji beta-egbochi.

N'ụfọdụ, mmeghachi omume nfụkasị mpaghara nwere ike ibute site na ebughi ihe metụtara ọgwụ a, dịka ọmụmaatụ, mgbakasị anụ ahụ na onye na-asacha ma ọ bụ ntụtụ na-adịghị mma.

N'okwu ndị na-adịghị ahụkebe mmeghachi omume nfụkasị systemic, a chọrọ ọgwụgwọ ozugbo. Mgbe ụfọdụ, enwere ike ịchọ mgbanwe insulin ma ọ bụ ịtụgharị uche.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

N'oge hypoglycemia, ikike onye ọrịa nwere itinye uche n'ihe nwere ike ịka njọ na ọnụego mmeghachi omume psychomotor nwere ike ibelata. Nke a nwere ike ịbụ ihe egwu dị na ọnọdụ ebe ike ndị a dị mkpa (ịnya ụgbọ ala ma ọ bụ igwe eji arụ ọrụ). A dụrụ ndị ọrịa ọdụ ka ha kpachara anya iji zere hypoglycemia mgbe ha na-anya ụgbọala.Nke a dị ezigbo mkpa maka ndị ọrịa nwere mgbaàmà dị nro ma ọ bụ ndị na-anọghị ya, na - ebido hypoglycemia ma ọ bụ nwee mmepe hypoglycemia ugboro ugboro. N'ụdị ndị ahụ, dọkịta ga-enyocha ike nke onye ọrịa na - anya ụgbọ ala.

Ngwongwo ogwu

Actrapid bụ insulin na-adị mkpụmkpụ, nke a na-ere ka ọ bụrụ ihe ngwọta maka ịgba ntụtụ. Ọgwụ nwere mmetụta hypoglycemic, na-enyere aka belata shuga ọbara. Nke a bụ n'ihi njem nke glucose na-arụ ọrụ n'ime sel nke anụ ahụ na akwara, nnabata ya ngwa ngwa na izu oke. Insulin na-akpali glycogenesis na lipogenesis, na-eme ka mmepụta protein na-eto ngwa ngwa ma belata ogo shuga na umeji.

Ọgwụ nwere insulin mmadụ, nke a na-enweta site na mgbanwe mkpụrụ ndụ ihe nketa. Ọzọkwa, ihe mejupụtara ahụ gụnyere glycerin, ihe ndị na-edozi nguzogide-acid acid, na zinc chloride. A na-ere ọgwụ ahụ na katrized mmiri 3 pụrụ iche nke edepụtara maka mkpụrụ sirinji.

Oge ọrụ insulin na-arụ ọrụ na-adabere na usoro onodu ogwu, ọnọdụ na ụzọ nchịkwa nke ịgba ntụtụ. Yabụ, iji ọgwụ ntụtụ, a na-ahụ mmetụta mbụ mgbe ọkara elekere gachara, ana-ahụpụta nsonaazụ kachasị mgbe awa 2 gachara. Ogologo oge insulin na ọbara bụ awa 8.

N'ime ụlọ ahịa ọgwụ, ị nwere ike ịchọta analogues nke ọgwụ ahụ: Iletin II Regular, Actrapid MS, Betasint na-anọpụ iche E-40, Maxirapid BO-S na ndị ọzọ. Enwere ike ịnwe dochie anya insulin naanị dị ka dọkịta si kwuo ka ya na ndị ndụmọdụ nwee nkwalite tupu oge eruo.

Mmetụta akụkụ na ị andụbiga mmanya ókè

Mmetụta ndị ọzọ insulin na-arụ nwere ike ime na mgbali elu anụ ahụ, na-emeghị usoro a tụrụ aro ya ma ọ bụ erighị ihe na-edozi ahụ. Ndị ọrịa shuga na-enwe nchegbu banyere ọzịza nke aka na ụkwụ, belatara ọgbụgba akwara, belata ọsụsọ, mkpọda na pallor nke anụ ahụ. Origha uche na oghere, ụjọ ịba ụba na ike ọgwụgwụ ga-ekwe omume.

Ọtụtụ mgbe, ndị ọrịa mamịrị na-eme mkpesa banyere isi ọwụwa na ọgbụgbọ, ọgbụgbọ na mmetụta siri ike nke agụụ. N'ọnọdụ ụfọdụ, mwepu nke mmụọ na mmepe nke insulin coma ga-ekwe omume.

Site n'ịba ụba nke ọgwụ ahụ, ndị ọrịa na-enweta mmeghachi omume nfụkasị. E gosipụtara ọnọdụ ahụ site na ọgbụgbọ, ọsụsọ gabigara ókè, nkụda mmụọ, obi obi, na nsogbu iku ume.

Ikekwe mmepe nke mmeghachi omume na mpaghara na ntụtụ: redness, ọzịza na itching. Site na inje mgbe niile n'otu mpaghara, lipodystrophy nwere ike ime.

Inggabiga usoro eji eme ọgwụ Actrapid na-eduga n'ọrịa hypoglycemia. A na-egosipụta ya site na adịghị ike, agụụ siri ike, aka na ụkwụ ịma jijiji na pallor nke anụ ahụ. Nkwụsị kachasị dị njọ na ọnọdụ a bụ hypoglycemic coma.

Contraindications:

Ime na lactation
Enweghị mgbochi ọ bụla na ojiji nke insulin n'oge ime, ebe insulin anaghị agafe ihe mgbochi placental. Ọzọkwa, ọ bụrụ na agwọghị ọrịa shuga n’oge afọ ime, nwa ebu n’afọ n’enwe nsogbu. Yabụ, a ga-aga n'ihu na-arịa ọrịa shuga n'oge afọ ime.
Ma ọrịa hypoglycemia na hyperglycemia, nke nwere ike ịmalite n'oge nke usoro ọgwụgwọ ahọpụtaghị nke ọma, na-abawanye ihe ojoo nke arụmọrụ nwa ebu n’afọ na ọnwụ nwa ebu n’afọ. Shouldmụ nwanyị dị ime nwere ọrịa shuga kwesịrị ileba anya n’oge ha dị ime, ha kwesịrị ijikwa ikike nke ọkwa glucose ọbara ka ọ dị mma, otu ndụmọdụ a si emetụta ụmụ nwanyị na-eme atụmatụ ime.
Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.
Mgbe ịmụchara nwa, mkpa ịba insulin na-alaghachi ngwa ngwa ekwuru ya tupu ọmụmụ nwa.
Enweghịkwa mmachi iji ọgwụ Actrapid NM n’oge ara.Ingmụrụ nne na-enye nwa ara adịghị ize ndụ nye nwa ahụ. Agbanyeghị, nne nwere ike imezi usoro onunu ogwu nke Actrapid NM na / ma ọ bụ nri.

Mmetụta:

Ọ dịkarịghị ala - mmeghachi omume anaphylactic. Ihe mgbaàmà nke hypersensitivity zuru oke nwere ike ịgụnye mbube akpụkpọ anụ ahụ, itching, ọsụsọ nke ukwuu, nsogbu nke eriri afọ, angioedema, dyspnea, palpitations, ọbara mgbada, mbelata / amaghị ihe.
Mmeghachi omume hypers nke a na-enwe n'ọgụgụ obi nwere ike ịbụ ihe na-egbu ndụ.

Ọrịa nke sistem
Ugboro ugboro - neuropathy akụkụ.
Ọ bụrụ n ’ọganiihu na nchịkwa glucose ọbara, ngwa ngwa, ọnọdụ akpọrọ“ neuropathy na-egbu mgbu ”nwere ike ịmalite nke na-agbanwe agbanwe.

Mmebi nke akụkụ nke ọhụụ
Ugboro ugboro - njehie na-ezighi ezi.
A na-ahụkarị ihe nregharị uche na ọkwa mbụ nke ọgwụgwọ insulin. Dịka iwu, mgbaàmà ndị a na-atụgharị.

O siri ike - ọrịa ịrịa ọrịa retinopathy. Ọ bụrụ na enyere njikwa glycemic zuru oke ogologo oge, ọ ga-ebelata ihe ọghọm nke inwe ọrịa mameti retinopathy. Agbanyeghị, ịbawanye uru nke ọgwụ insulin na mmụba dị mma na njikwa glycemic nwere ike ibute mmụba nwa oge na ogo ọrịa retinopathy.

Ọkpụkpụ nke anụahụ na anụ ahụ dị n'okpuru ala
Ugboro ugboro - lipodystrophy.
Lipodystrophy nwere ike itolite n’ebe a na-agba agba n’ihe banyere mgbe ha anaghị agbanwe ebe a na-agba agba n’otu mpaghara ahụ.

Mgbakasị ahụ si n'ahụ ya niile, yana mmeghachi omume na saịtị ịgba ahụ
Ugboro ugboro - mmeghachi omume na saịtị ịgba ahụ.
Na-emegide nzụlite insulin, mmeghachi omume nwere ike ime na saịtị ịgba nrị (redness nke akpụkpọ ahụ, ọzịza, itching, ọnya, hematoma guzobere na ntụtụ). Agbanyeghị, n'ọtụtụ oge, mmeghachi omume ndị a dị obere ma na-apụ n'anya n'oge usoro ọgwụgwọ.

Na - enweghị oge - afụli.
A na-ahụkarị ọzịza n'oge mmalite nke ọgwụ insulin. Dịka iwu, akara a dị ntakịrị oge na okike.

Emeputa:

Ngwọta maka injection Actrapid NM (ntuziaka maka iji ya, ọ na-edobe ya nke ọma) ka akwadoro maka ndị mmadụ na-arịa ọrịa shuga. Ọgwụ sitere na insulin mmadụ nwetara biosynthetically. Onye mepụtara ya bụ ụlọ ọrụ ọgwụ Novo Nordisk A / S si Denmark, na-arụ ọrụ na mmepe na imepụta ọgwụ maka ọrịa shuga. A na-eji Actrapid eme ihe naanị dị ka dọkịta si kwuo ya ma nyefee ya n'ụlọ ahịa ọgwụ yana fọm ndenye ọgwụ.

Akụkụ ike na mmetụta nke ọgwụ ahụ, na-egosi nzube ya

Actrapid NM bụ ihe nnọchianya hypoglycemic nke nwere obere oge. A na-emepụta ya n'ụdị mmiri na-enweghị atụ na enweghị isi na isi, nke ezubere maka nchịkwa n'okpuru anụ ahụ na intravenously. Akụkụ ahụ na-arụ ọrụ nke ọgwụ ahụ bụ insulin mmadụ nwere, enwetara site na iji usoro RDNA bayoloji na-eji Saccharomyces cerevisiae. Na 1 ml nke ihe ngwọta bụ 100 IU nke ihe na-arụ ọrụ, nke bụ insulin 0.035 anhydrous. Na mgbakwunye na ihe ahụ na-arụ ọrụ, ngwaahịa ahụ nwekwara mmiri mmiri, sodium n'ụdị hydroxide, zinc chloride, metacresol na hydrochloric acid.

A na-ere ọgwụ ahụ na karama doro anya nke mmiri dị milimita 10, ejiri ya na roba na-akwụsị. A na-akwachi kalama ọ bụla na igbe nke nnukwu mpempe akwụkwọ ma tinye ya na nkọwapụta ọgwụ.

Ngwongwo na-eme ka okpukpo okpukpo nke Actrapid NM bu n ’iwepu mmanu mmanu n’ahu mgbe emechiri insulin n’aka ndi n’ekwe ekwenti na imeju imeputa ya site na imeju. Ngwa eji mara ihe dị mkpirikpi.Mmetụta eji ya na-apụta n'ime ọkara otu awa mgbe ọ theụsịrị ya wee ruo awa 8. A na-ahụta nsonaazụ kachasị ike nke Actrapid NM na plasma ọbara mgbe awa 1.5-2 gachara.

A na-eji Actrapid NM mee ihe na ọgwụgwọ nke ọrịa mellitus na-akpata insulin na-emetụta ndị nọ n'afọ ndụ niile. N'ihi ihe ngwa ngwa, enwere ike iji ọgwụ ahụ mee ihe n'ọnọdụ ndị dị oke mkpa mgbe onye ọrịa nwere nsogbu na njikwa glycemic.

Ọnọdụ nke ịkpachara anya na ọgwụ

Ndị mmadụ na-arịa ọrịa shuga kwesịrị ịma na iji Actrapid NM egosighi maka ndị ọrịa niile. Ntuziaka maka iji gbochie ịhọpụta ọgwụ a maka ndị nwere:

• mmadu anabataghi ya.
• hypoglycemia.

Ojiji nke Actrapid NM na usoro ọgwụgwọ ụmụaka anaghị egbochi ya. Enwere ike iji ya mee ihe na ọgwụgwọ nke ụmụaka na ndị nọ n'afọ iri na ụma ndị chọrọ inje insulin iji nọgide na-enwe ọ̀tụ̀tụ̀ shuga dị n'ọbara nkịtị.

Ọ bụghị ahụkarị maka ọgwụ insulin banye na mgbochi placental, yabụ enwere ike iji ndị ọrịa dị ime na-enweghị mgbochi. Womenmụ nwanyị ndị na-akwado maka nne kwesịrị ịhọrọ oke ọgwụ kwesịrị ekwesị, nke ga-enyere ha aka ịchịkwa ọkwa shuga ọbara ha. Iji ọgwụ ahụ eme ihe na-ezughị ezu nwere ike ibute ọnọdụ nke hypoglycemia ma ọ bụ hyperglycemia - ọnọdụ ndị dị n’oge ime nwere ike ibute mmepe na ọnwụ nke nwa ebu n’afọ.

Ndị nne na - atụ anya kwesịrị iji nwayọ dozie ọgwụ Actrapid NM. Okwesiri iburu n’uche na n’oge onwa mbu, o choro ya na-agbadata, ma oge n’abia n’enwe ya. Mgbe ịmụchara nwa, mkpa nwanyị dị insulin ga-eji nke nta nke nta laghachi n'ike ọ nwere tupu mmalite nke ọnọdụ “dị mma”.

Actrapid NM adịghị emerụ ahụ ike nke ụmụ aka, yabụ, ọ dịghị mkpa ịbelata ojiji ya na ụmụ nwanyị na-enye nwa ara. Oge ụfọdụ nne na-eto eto nwere ike ịchọ idozi ọgwụ ụfọdụ.

N'ime ndị na-arịa oke akụrụ na ụkọ akụrụngwa, ike anụ insulin nwere ike belata. Ọ dị ha mkpa iji nlezianya nyochaa ọkwa nke glucose dị n'ọbara ma gbakọọ ego nke ọgwụ a na-enye n'otu n'otu, dabere na nsonaazụ nyocha.

Ojiji nke Actrapid NM n’ime ndị gbara afọ 65 ka a ga-ebu ụzọ megide nlekọta nke glucose oge niile. Iji zere mmepe nke nsonaazụ na-adịghị mma site na ọgwụgwọ, ndị ọrịa nọ n'afọ ndụ a kwesịrị ịgbalị ịghara ịgafe usoro ọgwụgwọ.

Ọgwụ anaghị emetụta ọmụmụ mmadụ. Amachibidoro ndị ọrịa na-eji ya amụ nwa mgbe niile.

Njirimara nke ngwa na nsonaazụ achọghị

A ga-enyerịrị Actrapid n'okpuru anụahụ ma ọ bụ intravenously. Usoro ọgwụgwọ nke ọgwụ ahụ dabere na mkpa onye ọrịa nwere insulin. Onye endocrinologist kwesịrị ịwụnye ya dabere na nyocha nke ọrịa mamịrị. Ọgwụ a nwere nsonaazụ obere oge, yabụ, ọ bụrụ na ọ dị mkpa, enwere ike ịkọ ya ya na insulin na-eme ogologo ọrụ.

A na-atụ aro ka ị solutionụọ ọgwụ ọgwụ nke Actrapid NM iji ọkara ọkara tupu nri. N'iji subcutaneous, ọ dị mma ịmebata ọgwụ ahụ na mgbidi ihu nke peritoneum. Inwekwara ike igba insulin n’ime ubu, apata ma ọ bụ mpaghara gluteal. Iji zere mmepe nke abụba abụba, onye ọrịa ahụ kwesịrị ịgbanwe ebe mmeghe nke ihe ngwọta ya mgbe niile. Site na mkpebi nke dọkịta, enwere ike ịkọwa onye ọrịa ahụ iwebata Actrapid NM intravenously. A na-eme usoro a n'ụlọ ọgwụ.

Ojiji nke Actrapid NM nwere ike ime ka mmepe nke mmeghachi omume ojoo na mmadụ.Ihe na-ebutekarị nsogbu ọgwụgwọ na usoro a bụ hypoglycemia, nke na-etolite n'ihi iji insulin buru ibu ma chọpụta na ọ na-arịa shuga dị n'ọbara. Site n'ụdị usoro a dị nro, mmadụ nwere mkpesa nke ịda mba, adịghị ike, akpịrị ịkpọ nkụ, ọgbụgbọ, anụ ahụ, enweghị agụụ, ikupụ ugboro ugboro, iku ume acetone.

Enwere ike ịmata hypoglycemia siri ike site na ọrịa nkwarụ, ịda mba, ọrụ ụbụrụ na-arụ ọrụ. Na enweghị usoro ọgwụgwọ zuru oke maka ọgwụgwọ a, ọrịa a nwere ike ibute ọnwụ nke mmadụ. N'ihe banyere hypoglycemia, ndị ọrịa mamịrị kwesịrị izere nlekọta insulin na-esote ma chọọ enyemaka ahụike ruru eru ozugbo enwere ike.

Na mgbakwunye na hypoglycemia, onye ọrịa na-anabata inractions Actrapid NM nwere ike ịnweta mgbaàmà nke hypersensitivity na ọgwụ ahụ, nke gosipụtara dị ka mbelata ọbara mgbali, ọnya anụ ahụ, mkpụmkpụ ume, tachycardia, sweating, dyspepsia, ede ede Quincke, turbidity, ma ọ bụ ọnwụ nke nsụhọ. A na-ahụta mmeghachi omume dị otú ahụ maka ọgwụ ọgwụ na-egbu ndụ ma chọọ nlekọta ahụike ozugbo.

Mmetụta ọghọm nke na-etolite na ụfọdụ ndị ji Actrapid NM gụnyere:

• nsogbu neuropathy ebe,
• nsogbu ọhụụ (myopia, hyperopia, astigmatism, hyperopia, myopia),
• mmebi abuba,
• Mmeghachi azụ nfụkasị (itching, urticaria),
• mmeghachi omume mpaghara (mgbu, itching, ọria, hematomas, hyperemia na ntụtụ insulin).

Ọrịa ọ bụla na-adịghị mma na-eme mmadụ mgbe ọ malitere iji Actrapid kwesịrị ịbụ ihe mere ọ ga-eji gaa na ọkachamara. Ileghara mmeghachi omume ojoo anya nwere ike ibute mmepe nke nsonaazụ ahụike na-enweghị atụ.

Ihe enyemaka mbu banyere n ’ịdoụbiga mmanya ókè, ị drugụ ọgwụ na nchekwa

Ojiji nke Actrapid NM na usoro onunu ogwu akari oke na-eduga na mmepe nke ịdoụbiga mmanya ókè, nke na-egosipụta onwe ya n’ụdị hypoglycemia. Enyemaka nye onye ọrịa dabere ogo ọnọdụ ya. Ibelata shuga dị n'ọbara iji mee ka ọ ghara ịga dọkịta. Nwere ike idozi ọnọdụ gị na onye ọrịa mamịrị site na iri ntakịrị shuga ma ọ bụ nri ọzọ nwere ọtụtụ carbohydrates.

Na nnukwu hypoglycemia, tinyere ọrịa ala, onye ọrịa chọrọ nlekọta ahụike mberede. Iji wepu ihe egwu dị na ndụ, a na-egbu ya glucagon na dextrose. Iji gbochie ịba ụba glucose ugboro ugboro, a na-enye onye ọrịa nri nri nwere carbohydrate ka ọ tụchara.

Insulin insulin na otu ọgwụ ọgwụ ụfọdụ na-emekọrịta ihe. Maka ndị na-ewere beta-igbochi, ọgwụ mgbochi tetracycline, sulfonamides, steroidal anabolics, carbonic anhydrase inhibitors, monoamine oxidase na ACE inhibitors, ketoconazole, theophylline, mebendazole, clofibrate, ọgwụ na-akụda shuga maka iji ọnụ mee ihe, a ghaghị iburu ọgwụ niile n'uche;

Na-ejikọ akụrụngwa hypoglycemic nke Actrapid NM site na ya n'otu oge nlekọta na glucocorticosteroids, mgbochi mkpịsị ọnụnụ, ihe mgbochi calcium, thiazide diuretics, sympathomimetics, morphine, heparin, danazole, tricyclic antidepressants.

Mgbe ị na-agwakọta ọgwụ insulin na salicylates na reserpine, mmeghachi omume na-atụghị anya ya nwere ike ime. Mgbe ị na-a theụ ọgwụ na mmanya na ethanol nwere ọgwụ n'ụzọ yiri ya, ọ na-enwewanye ike ma na-adịte aka.

Actrapid NM ekwekọghị na ọgwụ ndị dabere na sulfites na thiols. Mgbakwunye ha na ngwọta ahụ na-eduga mbibi ya.

Ndụ nchekwa nke Actrapid NM bụ nanị ọnwa 30 site na ụbọchị emepụtara.A na-atụ aro vials na-enweghị ọgwụ nke ọgwụ a ka echekwa ya na friji na okpomọkụ nke 2 Celsius ruo 8 Celsius. Ọ dị mkpa iji hụ na insulin anaghị ajụ oyi, n'ihi na nke a na-ebelata ihe hypoglycemic Njirimara.

Mgbe emepechara karama ahụ ọgwụ a ga-edobe ya n'ime ụlọ dị n'ime ụlọ ebe echekwara site na ìhè na-enwu. Ekwesịrị ị consumedụ insulin ebi akwụkwọ maka ụbọchị 45. Ọgwụ, nke na-adịgide mgbe njedebe nke oge a, amachibidoro iwu.

Daalụ maka nzaghachi gị.

Nkwupụta

Megan92 () izu abụọ gara aga

Ha kwuru na ọ gaghị ekwe omume ịgwọ ya kpamkpam.

Daria () Izu abụọ gara aga

Echekwara m na ọ gaghị ekwe omume, mana mgbe m gụchara isiokwu a, echefurula m ọrịa a "enweghị ọgwụgwọ".

Megan92 () daysbọchị 13 gara aga

Daria () ụbọchị 12 gara aga

Megan92, yabụ edere m na nkwupụta mbụ m) Mpempe akwụkwọ naanị ma ọ bụrụ na - njikọta na isiokwu.

Sonya ụbọchị iri gara aga

Nke ahụ ọ́ bụghị ịgba alụkwaghịm? Gịnị kpatara ha ji ere ahịa na ntanetị?

Yulek26 (Tver) ụbọchị iri gara aga

Sonya, olee mba i bi? Ha na-ere ya na Internetntanetị, n'ihi na ụlọ ahịa na ụlọ ọgwụ na-ere ọgwụ ọjọọ. Na mgbakwunye, ịkwụ ụgwọ naanị mgbe nnata gachara, ya bụ, bu ụzọ lelee ya, lelee ya ma kwụchaa ya. Ee, ugbu a kwa, ha na - ere ihe niile dị na ntanetị - site na akwa ruo na igwe na arịa.

Nzaghachi Editọ ụbọchị 10 gara aga

Sonya, ndewo. A naghị ere ọgwụ a maka ịgwọ ọrịa shuga mellitus n'ezie maka netwọ ahịa ọgwụ iji zere ị overụbiga mmanya ókè. Ruo taa, ịnwere ike ịtụ naanị websaịtị gọọmentị. Nwee ahụike!

Sonya ụbọchị iri gara aga

Insulin Actrapid bụ ọgwụ eji eme ihe maka ụdị 1 na ụdị ọrịa shuga 2, yana maka enyemaka nke nnukwu ọgụ nke hyperglycemia. Ọ na-edozi shuga dị n'ọbara ma na-akwado ọdịmma. Iji meziwanye nsonaazụ ma nọgide na-enwe ọkwa glucose dị mma, a na-atụ aro ijikọta ọgwụ ahụ na insulin na-arụ ọrụ ogologo oge na ọgwụ antidiabet ndị ọzọ.

Ntụziaka pụrụ iche

Iji nweta nsonaazụ a na-atụ anya site na iji ọgwụ ahụ, a ga-ejikọ ya na insulin na-arụ ọrụ ogologo oge ma ọ bụ nke na-ajụ. N'oge ọgwụgwọ, nyochaa ọkwa shuga dị n'ọbara iji chọpụta oge na gbochie mmepe nke hyper-ma ọ bụ hypoglycemia.

Iji zere lipodystrophy, gbanwee saịtị ntụtụ oge niile.

A na - eji insulin Actrapid eme n'oge ime. N’ime oge nke atọ, mkpa iji homonụ na-ebelata, ma n’ụbọchị echi ya na-abawanye, yabụ, usoro a ga-eji nwayọ nwayọ. Dọkịta kpebisiri ike iji ọgwụ ha mee ihe n'okwu nke ọ bụla, na-eburu n'uche njirimara nke anụ ahụ na oge ịtụrụ ime.

Mgbe ọ mụsịrị nwa, nwanyị kwesịrị ịlaghachi n'okpo insulin ọ nwetara tupu ịtụrụ ime. Agbanyeghị, n'oge a na-enye nwa ara, mkpa nke homonụ nwere ike ibelata, yabụ, ọ dị mkpa ileba ọkwa glucose na ọdịmma gị anya.

Mgbe ị na-eji ọgwụ ahụ, hapụ ọrụ chọrọ ọgwụgwọ ngwa ngwa na ịbawanye ụba. Ihe mgbochi ndị a metụtara ịnya ụgbọ ala. Nke a bụ n'ihi eziokwu ahụ na enwere hypoglycemia, enwere ike ibelata nzaghachi nye mkpali mpụga.

Hypo- na hyperglycemia mgbe ị na-eji ọgwụ ahụ

Ojiji insulin Actrapid nwere ike iduga mmepe nke hypoglycemia (nnukwu shuga na shuga) ma ọ bụ hyperglycemia (mmụba nke glucose). Nke a bụ n'ihi na enweghị nrube isi na usoro ọgwụgwọ a tụrụ aro ya, erighị ihe na-edozi ahụ (nri iri nri ma ọ bụ ịreatụbiga ya ókè), ịgbatịkwu anụ ahụ, yana ịwụnye injections ma ọ bụ nchịkwa na-adịghị mma nke ihe ngwọta.

Ihe omuma ndi a bu akparamagwa nke hyperglycemia: akpiri ojoo, ure ugboro ugboro, nri riri nne, ahuhu ya na akpukpo aru. Site na ketoacidosis, isi acetone sitere na onu.Mgbaàmà na-akụ na-egosi na ịchọrọ inyocha ọbara ọbara gị ma, ọ bụrụ na ọ dị mkpa, tinyegharịa Actrapid ọzọ.

Ihe hypoglycemia bụ mmụba na agụụ, ụcha na akpụkpọ ụkwụ na-ama jijiji. Iji kwụsị ihe ngosi ahụ ma gbochie mmepe nke hypoglycemic coma, a na-atụ aro onye ọrịa ka ọ rie obere shuga ma ọ bụ ngwaahịa carb dị elu (kuki, swiiti), juiceụọ mmiri ọ orụ sweetụ ma ọ bụ tii. N'ihe banyere mmụọ ịmara, a na-edozi ngwongwo dextrose 40% na glucagon. Iji gbochie nlọghachi azụ ka ọ gbasachaa, a na-atụ aro onye ọrịa ka ọ rie nri nwere nnukwu carbohydrates ngwa ngwa.

Ọnọdụ nchekwa

Wepụ ìhè anyanwụ. Zere ikpo oke ma ọ bụ ịcụbiga mmanya ókè ma ghara ikwe ka asachalụ ahụ belata. Jụ iji ọgwụ ahụ ma ọ bụrụ na ọ gbanweela agba ma ọ bụ flakes (sediment) apụtala. Dowe ọgwụ ahụ ka ụmụaka ghara inweta ya.

Actrapid HM Penfill (Actrapid HM) - nkwadebe nke insulin mmadụ, nke emepụtara site na iji mkpụrụ ndụ ihe nketa.

O nwere oge dị mkpirikpi nke ime ihe na pH na-anọpụ iche. Edebere ya na uzo ozo. HM n'aha ọgwụ ọjọọ na Latin pụtara "Injinịa mkpụrụ ndụ mmadụ, monocomponent."

N'isiokwu a, anyị ga-atụle ihe mere ndị dọkịta ji depụta Actrapid NM, gụnyere ntuziaka maka ojiji, analogues na ọnụ ahịa ọgwụ a na ahịa ọgwụ. AKR REAKA ndị mmadụ ejirila Actrapid gụọ ihe ha kwuru.

Omume ọgwụ

Nnukwu insulin nke mmadụ na-eme n’onwe ya. Ọ bụ insulin nke oge ihe ji arụ ọrụ.

Na -emezi usoro glucose, nwere mmetụta anabolic. Na akwara na akwara ndị ọzọ (ewezuga ụbụrụ), insulin na - eme ka glucose na amino acids nwee intracellular intracellular. Insulin na - akwalite ntụgharị nke glucose na glycogen na imeju, na - egbochi gluconeogenesis ma na - akpali ntụgharị nke oke glucose na abụba.

Ihe ngosi maka ojiji

Bụrụ na nsogbu ndị gbasara akụrụngwa ma ọ bụ ọrụ ịba ọcha n'anya insulinbelata. Ya mere, ịkwesịrị idozi usoro ọgwụgwọ.

Ntuziaka maka iji Actrapid na-egosi na enwere ike iji ya na yana ogologo eme insulins.

A na-enye ọgwụ ahụ ọkara ọkara tupu nri ma ọ bụ nri nwere carbohydrates. Dịka iwu, a na-eme inje subcutaneously na mpaghara nke akụkụ ihu ime. Nke a na-enye nnabata ngwa ngwa. Na mgbakwunye, enwere ike ịme ntanetị n'apata ụkwụ, akwara deltoid nke ubu ma ọ bụ buttock. Iji gbochie lipodystrophyỌ dị mkpa ịgbanwe saịtị ndị gbanye mmadụ.

Nchịkwaa nke intraven ka nwere ike ikwe naanị ma ọ bụrụ na ndị ọkachamara n ’ọgwụ. N'ime intramuscular, a na-enye ọgwụ ahụ naanị ka onye ọkachamara nyere ya ndụmọdụ.

Ofzọ nke ngwa

Emere usoro ọgwụgwọ dị mkpụmkpụ nye ndị nwere ọrịa shuga - n’otu n’otu. Ọ niile dabere n'ọkwa glucose dị n'ọbara. Tupu dọkịta endocrinologist kwupụta ọgwụgwọ ya na Actrapid nke nwere insulin, ịkwesịrị ịmụ ntuziaka. Ntuziaka maka iji ọgwụ ahụ na-akọwa n'ụzọ zuru ezu:

• ihe ọgwụ ahụ mere
• usoro nke ngwa
• contraindications
• mmetụta
• ihe mejupụtara.

Ofzọ itinye ihe eji eme ihe na-adabere n'ụdị ntọhapụ. A na-agunye insulin. Enwere ike ilekọta ya n'okpuru anụ ahụ n'ime ihe mgbochi, akwara aka na afọ. Ihe dị iche bụ mgbe achọrọ ọgwụ iji intramuscularly ma ọ bụ intravenously. Ọgwụ, nke a na-eji subcutaneously, nwere ụdị katriiki.

• a na-enye ọgwụ ahụ ka nkeji iri atọ tupu nri,
• ugboro ugboro n'otu ebe, etinyela insulin,
• A ga-ezere ịbanye n'ime arịa ọbara,
• mgbe nchịkwa insulin gasịrị, a naghị atụ aro ka ntinye ebe a na-agba ya ka ọ metụ ma pịa ya.
• ọ bụrụ na ịgwakọta insulin na-eme obere oge, ị ga-enye ọgwụ mgbochi ozugbo.
• a na-agbakọ doses dabere na onye ọrịa, okenye ma ọ bụ nwatakịrị,
• a na-ahụ doses dabere na ngwakọta ọgwụ,
• a bụrụ Coma ma ọ bụ acidosis, a na-ahụ ọgwụ ahụ intravenly,
• a na-eme ọgwụ inje n'okpuru nlekọta nke dibịa.

Enwere ndị nwere ọrịa shuga, nke ọrịa na-efe efe na-agbagha. N'okwu a, ọ dị mkpa ịtụle ọnọdụ ha. Mgbe ị na-ewere Actrapid dabere na insulin, a na-atụ aro ka ntuziaka maka ojiji. Nweta ndụmọdụ n’aka dọkịta gị. Omume ndị nweere onwe ha n'iji ọgwụ ahụ ga-ebute nsonaazụ na-adịghị mma.

Ntụziaka ahụ, nnabata nke ekwesịrị inyocha, ga-azọpụta gị n'ọtụtụ nsogbu. Mana enwere ụdị ikpe ahụ na mmadụ na-eme. Ya mere, a na-atụ aro ị paya ntị na mgbaàmà ndị na-enweghị nkọwa:

• isi ọwụwa
• ike ọgwụgwụ
• ihi ụra mgbe niile
• arrhythmia,
• oké ọsụsọ, ọbụna n'oge oge oyi,
• ndaba,
• akpụkpọ ahụ na-achazi ọcha
• vomiting
• Ọnọdụ nna nna.

Ekwesiri iburu n’uche na onye na-enyocha ọnọdụ ahụ ogologo oge, na-a certainụ ọgwụ ụfọdụ, ọ nwere ike ọ gaghị achọpụta oke nrịanrịa. Ọrịa dị iche iche na-enye ọgwụ dịgasị iche iche. Imezi ọnọdụ onye ọrịa a bụrụ na ị doụbiga ya ókè enwere ike iji ya:

• ntinye nke ihe ngwọta pụrụ iche n’okpuru anụ ahụ,
• ntinye nke glucose di na ala.

Suchzọ ndị dị otú a nwere ike mee ka onye ọrịa nwere ọrịa mellitus belata ma gbochie ya ịdaba.

Ngwakọta na ịhapụ ụdị

Ngwakọta ọrụ na-arụ ọrụ n'ime ihe mejupụtara bụ insulin nke mmadụ n'ụdị etisasịworo. Ndị pụrụ iche n’ime ihe mejupụtara: zinc chloride, glycerol, mmiri injection, metacresol, sodium hydroxide.

A na-ere ọgwụ ahụ n'ụdị injectable, a na-enwekwa ihe eji eme ọgwụ nm penfill, nke a na-erekwa ka ọ ga-esi wee dochie injections dị n'okpuru.

Usoro nke Actrapid NM

Ngwa a nwere insulin nke mmadu nwetara site na inyocha mkpụrụ ndụ ihe nketa. Maka nrụpụta ya, a na-eji DNA sitere na yistcharomycetes yist.

Insulin na-ejikọ ndị nabatara ya n ’sel sel nke a na - eme ka glucose si n’ọbara banye n’ime sel.

Na mgbakwunye, insulin na-egosipụta insulin omume ndị dị otú a na usoro metabolic:

1. A na - akwalite usoro glycogen na imeju na akwara anụ ahụ
2. Na-akwalite ojiji nke glucose site na mkpụrụ ndụ akwara na anụ ahụ adipose maka ume
3. Mmebi nke glycogen belatara, dịkwa ka nguzobe nke mkpụrụ ndụ glucose ọhụrụ n’ime imeju.
4. Ọ na - eme ka abụba a na - eme ike ma belata mmebi abụba
5. N'ime ọbara, njikọ nke lipoproteins na-abawanye
6. Insulin na-eme ka uto sel na nkewa too
7. Na-eme ka njikọta protein na --ebilata ndakpọ.

Ogologo oge nke Actrapid NM dabere na dose, saịtị injection yana ụdị ọrịa shuga. Ọgwụ na-egosi akụrụngwa ya ọkara ọkara mgbe nchịkwa, a na-ahụkarị kachasị ya mgbe awa 1.5 - 3.5 gasịrị. Mgbe oge asaa nke asaa ruru elekere asatọ gachara, ọgwụ ahụ kwụsịrị ihe ọ bụla ma enzyme bibie ya.

Isi ihe na-egosi maka ojiji nke insulin insulin bụ mbelata ọkwa glucose na ọrịa mellitus, ma maka iji ya mgbe niile yana maka mmepe nke ọnọdụ mberede.

Arụ ọrụ n'oge ime

Enwere ike inye ọgwụ insulin Actrapid NM iji belata hyperglycemia n'ime ụmụ nwanyị dị ime, ebe ọ bụ na ọ naghị agafe ihe mgbochi placental. Enweghị ụgwọ maka ọrịa shuga na ụmụ nwanyị dị ime nwere ike ịdị ize ndụ nye nwa ahụ.

Nhọrọ nke doses maka ụmụ nwanyị dị ime dị oke mkpa, ebe ọ bụ na ọkwa shuga dị ala ma dị ala na-akpaghasị usoro ọmụmụ ahụ ma na-eduga mmebi, yana ịbawanye n'ihe ize ndụ nke nwa ebu n'afọ.

Site na nhazi atụmatụ ịtụrụ ime, ndị endocrinologist ga-enyocha ndị na-arịa ọrịa shuga, ha na-egosikwa na ha na-enyocha ọkwa nke glucose ọbara.Mkpa insulin nwere ike ibelata n’oge ọnwa mbụ nke ịtụrụ ime ma mụbaa n’ime nke abụọ na nke atọ.

Mgbe amuchara nwa, ogo nke glycemia na-alaghachikwute ọgụgụ ndị mbụ dị tupu ime ime.

Maka ndị nne na-azụ nwa, nchịkwa nke Actrapid NM adịghị n'ihe ize ndụ.

Mana e nyere ụba ihe achọrọ maka nri, nri kwesiri ịgbanwe, ya mere na insulin.

Etu esi etinye Actrapid NM?

A na-enye insulin insịlị subcutaneously na intravenously. A na-ahọrọ usoro onunu ogwu kpamkpam. Dị ka ọ dị, achọrọ insulin dị n'etiti 0.3 na 1 IU kwa ụbọchị kwa kilogram nke ịdị arọ onye ọrịa. Site na nguzogide insulin na ndị ntorobịa ma ọ bụ buru oke ibu, ọ dị elu karị, maka ndị ọrịa nwere ihe nzuzo insulin nke onwe ha, ọ dị ala.

N'ime ụzọ ụgwọ ọrịa shuga, nsogbu nke ọrịa a na-etolite obere oge ma emesịa. Yabụ, ịdị na-enyocha glucose ọbara mgbe niile na ịhọrọ ọgwụ insulin nke na-ejigide ọkwa a mgbe ọ bụla.

Actrapid NM bụ insulin na-adị mkpụmkpụ, ya mere a na-ejikọkarị ya na ụdị ọgwụ ogologo oge. Ekwesịrị inye ya ọkara otu awa tupu nri, ma ọ bụ nri dị ọkụ nke nwere carbohydrates.

Estzọ ntinye ọsịsọ bụ ntụtụ n’ime afọ. Iji mee nke a, dị njikere itinye sirinji insulin na mkpo akpụkpọ ahụ. A na-ejikwa mpaghara hips, isi, ma ọ bụ ubu. A ga-agbanwerịrị ebe a na-agba agba gburugburu ka ọ ghara imebi mbibi anụ ahụ.

Site na mmepe nke nephropathy mamịrị, mkpa insulin na-ebelata, ya mere, a na-atụgharị dose ahụ na-eburu n'uche njigide mmiri glomerular na ọkwa nke ọdịda akụrụ. Na ọrịa nke adrenal gland, thyroid gland, pituitary gland, yana mmebi imeju, oke ọgwụ insulin chọrọ chọrọ nwere ike gbanwee.

Mkpa insulin na-agbanwekwa na nrụgide mmetụta uche, mgbanwe na mmega ahụ ma ọ bụ mgbanwe na nri dị iche. Ọrịa ọ bụla bụ ihe kpatara mgbazi nke insulin kwenyero na dọkịta gị.

Ọ bụrụ na ịnwe insulin dị ala, ma ọ bụ onye ọrịa ahụ n'onwe ya akagbuola insulin, hyperglycemia nwere ike ịmalite na mgbaàmà ndị a:

• Mmụba iro ụra na ike ọgwụgwụ.
• Akpịrị ịkpọ nkụ.
• Ogbugbu na ọgbụgba na-anọpụ iche.
• Akpụkpọ anụ na-acha uhie uhie na akọrọ.
• Urination mmụba.
• Agụụ agụụ.
• Ọnụ kpọrọ nkụ.

Ọrịa nwayọọ nwayọọ na - ebido - ọtụtụ awa ma ọ bụ ụbọchị. Ọ bụrụ n ’idozilata shuga ọbara gị, ọ na-amalite. Ihe e ji mara ya bu isi acetone n’igwe ikuku ekuru. Ihe ize ndụ nke hyperglycemia na-abawanye na ọrịa na-efe efe na ahụ ọkụ.

Mgbanwe site n'otu ụdị insulin gaa na nke ọzọ chọrọ nhọrọ nke usoro ọhụrụ. Iji mee nke a, ịkwesịrị ịgụta ọgwụ endocrinologist. Agaghị enwe ike iji insulin Actrapid na nfuli insulin, na enweghị enweghị nchebe na vial ahụ, ọ bụrụ na echekwara ya n'ụzọ na-ezighi ezi ma ọ bụ kpọnwụrụ akpọnwụ, yana ọ bụrụ na ngwọta ya bụrụ urukpuru.

Maka ntụtụ, ị ga-eso iwu ndị a:

1. Kpoo ikuku n'ime sirinji, nke ya na dose enyere.
2. Tinye sirinji site na nkwunye ma pịa piston.
3. Tụgharịa karama ahụ.
4. Were otu insulin n’ime sirinji.
5. Wepu ikuku ma lelee dose.

Mgbe nke a gasịrị, ịkwesịrị igba ya: were anụ ya banye n'oghere ma fanye ntụtụ ahụ na ntọala ya, na ogo 45. Insulin kwesịrị ịdakwasị anụahụ.

Mgbe ogwu ogbugba gasịrị, agịga kwesịrị ịdị n'okpuru akpụkpọ ahụ ọ dịkarịa ala 6 sekọnd iji nye ọgwụ ahụ n'ụzọ zuru ezu.

Mmetụta dị na Actrapid

Nsonaazụ kachasị na-emetụta mgbe a na-agabiga insulin bụ hypoglycemia. Ọ na --eme ọ bụla na mberede, ya na pallor nke anụ ahụ, ọsụsọ oyi, oke ike ọgwụgwụ ma ọ bụ adịghị ike, oke ntụsara ahụ metụtara, nchekasị, ụjọ na aka.

Rationta ụta ga-agbada, ụra na-ebilite, mmetụta nke agụụ, imerụ anya na-akawanye njọ.Isi ọwụwa na ọgbụgbọ, ọgbụgbọ na palpitations na-aga n'ihu. Sedị siri ike nke ịda suga nwere ike ịmetụta ọrụ ụbụrụ na enweghị mmụọ ma ọ bụ ọbụna ọnwụ.

Ọ bụrụ na ọrịa shuga dị ogologo oge, ya na neuropathy mamịrị, na ọgwụgwọ nke beta-igbochi ma ọ bụ ọgwụ ndị ọzọ na-eme ihe na sistemụ ụjọ, mgbe ahụ ihe ịrịba ama mbụ nke hypoglycemia nwere ike ịbụ nke na-adịghị mma, yabụ ịkwesịrị ilekwasị anya mgbe niile na ọkwa glucose ọbara.

Maka ịdị nro, ịkwesịrị ị sugarụ shuga ma ọ bụ ihe ọ juiceụ juiceụ, kuki, mbadamba glucose. N'ọnọdụ siri ike, a na-edozi glucose 40% n'ọbara, na glucagon ka a na-elekọta intramuscularly ma ọ bụ subcutaneously. Mgbe onye ọrịa mechara nwetaghachi mmụọ, ọ kwesịrị iri nri nri ya na carbohydrates dị mfe.

Mmegide nke glycemia nwere ike ikwugharị n'ime otu ụbọchị, yabụ, ọbụlagodi na nhazi nke glucose dị mkpa, ọ dị mkpa iji mee ka njikwa na ọdịnaya ya dị ike. Ndị ọrịa dị otú a chọrọ ka a na-enweta carbohydrates ugboro ugboro.

Nsonaazụ ndị ọzọ dị ụkọ ma enwere ike ịda n'ụdị:

• Ọrịa ụkwara ume ọkụ ma ọ bụ nke hives. Ọ na-esikarị ike ịgwọ ọrịa mmadụ - mmeghachi omume anaphylactic.
• Ọsụsọ, ọgbụgbọ, na isi ọwụwa.
• Rateba ụba n’obi.
• Ọkpụkpụ akwara ozi.
• Ntughari ezughi oke ma obu mmepe nke retinopathy.
• Lipodystrophy na ntaneti, itching, hematoma.
• Puffiness, akpan akpan ke akpa ụbọchị iji.

Ofdị ntọhapụ na nchekwa nke insulin Actrapid NM

Ọgwụ dị na netwọsụ ndị na - ere ahịa nwere ike ịdị n'ụdị: insulini nke NM Penfill (ọ chọrọ mkpịsị insulin pụrụ iche), yana insulin na vials (a chọrọ sirinji insulin maka injections).

Udi nkwadebe abuo a nwere ihe omuma ya na ntughari nke 100 IU na 1 ml. Karama nwere ihe dị milimita iri, na katriiki - 3 ml nke iberibe ise n’otu ngwugwu. Ntuziaka maka iji ya so na ụdị ịtọhapụ ọ bụla.

Ọnụahịa Actrapid na karama dị ala karịa nke ụdị penfil. Ọnụahịa ọgwụ ahụ nwere ike ịdị iche na agbụ ndị na-ere ahịa. Na mgbakwunye, mgbanwe mgbanwe ego nke mgbanwe ego na-emetụta nguzobe nke ọnụahịa, ebe nke a bụ ọgwụ nke ihe dị mbubata. Ya mere, ọnụahịa Actrapid dị mkpa naanị n'ụbọchị ịzụta.

A na-echekwa insulin na friji pụọ na friza n'oge okpomọkụ abụọ ruo asatọ. Can nweghị ike ifriizi ya. Enwere ike ịchekwa karama mepere emechi na n ụlọ okpomọkụ maka izu isii, jide n'aka na ịchebe ya site na ọkụ na ọkụ n'ime igbe kaadi. Vidio dị n'isiokwu a ga-aza ajụjụ banyere nchịkwa insulin.

Ihe dị mkpụmkpụ bụ insulul Actrapid. Ọ dị n ’ọnya ma jiri ya gwọọ ọrịa shuga 1 na ụdị nke 2, yana maka nlekọta mberede maka hyperglycemia. Karịsịa, a na-eji ya na ọrịa shuga na-akpata insulin. Ọrịa dị insulin mkpa nke ndị ọrịa dị otú a. Maka ịchịkwa ọkwa shuga dị n'ọbara karịa, agwakọta ụdị ọgwụ a. Na otu n'ime ọgwụ ịhọrọ bụ Actrapid - insulin obere.

Njirimara ọgwụ

Insulin "Actrapid NM Penfill" bụ ihe eji egbochi mmiri ọgwụ. Ọgwụ ahụ nwere ọgwụ hormone nke mmadụ na-enweta site na mgbanwe n’usoro mkpụrụ ndụ. 1 ml nke ihe ngwọta nwere 3.5 mg nke insulin. Na mgbakwunye, glycerin, zinc chloride na ihe ndị pụrụ iche na-agbanye na mmiri maka ịgba ntụtụ, nke na-emepụta ọkwa achọrọ nke acid-base. Ọgwụ dị na katridges pụrụ iche maka mkpịsị ọsụgharị 3 ml. Nke a bụ nkezi otu ụdị, mana n'ọnọdụ ụfọdụ achọrọ ka ọ mụbaa.

Na mgbakwunye n'ụdị ntọhapụ a, enwere insulin Actrapid NM na vials 10 ml. O nwekwara ihe homonụ nke mmadu na-enweta site na iji usoro inyocha mkpụrụ ndụ. Enwekwara mmechu nke ogwu ahu - Actrapil MS. A na-eji ya eme obere oge, ebe ọ bụ insulin na-anọpụ iche insulin.

Ihe nke ogwu a

Insulin na-abanye n’ime sel ma na-emetụta usoro metabolism, na-eme ka njem glucose dị mma. N'ihi nke a, nnabata anụ ya na-abawanye. A na-akpalikwa Glycogen na mkpụrụ ndụ akwara na-abawanye. Insulin "Actrapid" na-ezo aka ọgwụ na-adị obere oge. Mmetụta hypoglycemic ya nwere ike ịdị iche dabere na usoro na ebe ịgba ọgwụ, usoro onyonyo yana njiri mara ndụ onye ọrịa. Mana ọtụtụ oge, nsonaazụ nke ọgwụ na-amalite mgbe ọ fọrọ nkeji iri atọ ka ọ na-eru 8 awa. Mmetụta kachasị na-adaba na awa 2-3 mgbe iwebata usoro a. Oke oriri kacha elu nwere Actrapid NM, ọkachasị ma ọ bụrụ na etinyere ya n'ụzọ ziri ezi. Ọ kachasị mma ịme ntụtụ na mpempe akpụkpọ ahụ na afọ, yabụ ọgwụ ahụ ga-amalite ime ngwa ngwa.

Ngwurugwu mgbochi na nsonaazụ ya

Patientsfọdụ ndị ọrịa enweghị nnabata nke insulin. Mgbe ụfọdụ, a ga-ahụta mmeghachi omume nfụkasị ihe ndị ọzọ dị na ọgwụ ahụ. N'ọnọdụ ndị a, a na-edenye insulin ọzọ. A na - egbochi ọgwụ iji ọgwụ eme ihe ma ọ bụrụ na hypoglycemia. Yabụ, tupu mmeghe, ọ dị mkpa inyocha ọkwa shuga dị n'ọbara. Cannweghị ike iji “Actrapid” maka ọrịa kansa a na - eme ya - insuloma. Ihe ogwu a amaghi ihe umuaka, ma ndi nwanyi di ime.

Mgbe ị na-eji insulin “Actrapid”, mmetụta ndị na-esote ya nwere ike ime:

Iwebata insulin "Actrapid"

Uzo ochichi nke ogwu a,, ufodi, bu igba obara. Maka nke a, achọrọ sirinji insulin pụrụ iche. Ha nwere ngụsị akwụkwọ na-enye gị ohere ịlele ego ole ọgwụ dị. Ọtụtụ mgbe, a na-eji mkpụrụ akwụkwọ sirinji pụrụ iche maka insulin “Actrapid NM” eme ihe. N'ụzọ dị otú a, ịgba ntụtụ kachasị adaba. Ekwesịrị ime na afọ ma ọ bụ ubu, naanị n’oghere dị n'okpuru ala, na-ezere ntụtụ intramuscular. Mgbe ụfọdụ ọgwụ ntụtụ ga - agbatị n’apata ụkwụ ma ọ bụ n’ọkpụkpụ, mana na nke a, ọgwụ ahụ na-agbakarị njọ.

Etu esi ahazi insulin Actrapid? Ntụziaka ahụ kọwara usoro a dịka ndị a:

• ịkwesịrị ịbịaru ego ziri ezi na sirinji ahụ n'ime karama ma ọ bụ tinye katrijị n'ime mkpịsị sirinji pụrụ iche,
• jiri aka ekpe gi ichikota mkpịsị aka ya abụọ n’afọ, apata ụkwụ ma ọ bụ ubu,
• ragide agịga ahụ n'ime okpokoro n'oghere nke ogo 45,
• jiri nwayọ gbanye nsị n'okpuru anụ ahụ,
• hapụ agịga maka 5-6 sekọnd,
• wepu ya nke oma, oburu na obara aputaputara, odi nkpa igbari ebe ngbanye ahihia.

Insulin "Actrapid": ntuziaka maka ojiji

Naanị dọkịta na-aga ya nwere ike ikpebi usoro achọrọ ọgwụ ole ọ chọrọ. Ọ dabere na ntụgharị metabolism nke onye ọrịa, ụzọ ndụ ya, usoro nri ya na ihe insulin chọrọ. Na nkezi, a chọghị ihe karịrị 3 ml kwa ụbọchị, mana ihe ngosi a nwere ike ịba ụba karịa ndị buru ibu, n'oge afọ ime ma ọ bụ na - egbochi ihe anụ ahụ. Ọ bụrụ na pancreas emepụtara insulin dịkarịa ala, a ga-enyerịrị ya na obere doses. A na-ebelata mkpa insulin na ọrịa nke imeju na akụrụ.

Inje nke "Actrapid" na-eme ugboro abụọ n'ụbọchị. Ọ bụrụ na ọ dị mkpa, ịnwere ike iwelie ugboro ole ojiji ruo ugboro 5-6. Ọkara elekere mgbe ịgba ọgwụ mgbochi ahụ, ị ​​ga-eri nri ma ọ bụ opekata mpe nwere carbohydrates.

Ọ ga-ekwe omume ịgwakọta ọgwụ a na ọgwụ ogologo oge. Dịka ọmụmaatụ, a na-ejikarị ngwakọta: insulin "Actrapid" - "Protafan". Ma naanị dọkịta nwere ike ịhọrọ usoro nchịkwa nchịkwa mmadụ. Ọ bụrụ na ọ dị mkpa, tinye insulin abụọ n'otu oge a na-achịkọta ha na otu sirinji: nke mbu - "Actrapid", na nke ahụ - insulin na-arụ ọrụ ogologo oge.

Ihe ị ga - eme n’ihe banyere hypoglycemia

N'ọnọdụ ụfọdụ, ọ na - abụkarị mgbe ị anụbiga mmanya ókè, onye ọrịa na - ebute hypoglycemia. Ọ nwere ike ịpụta ma ọ bụrụ na onye ọrịa ahụ riri nri ma ọ bụ gosi oke mmega ahụ.Ọnọdụ a na-eme na mberede. Onye ọrịa ahụ na-enweta mgbaama ndị a:

• tachycardia
• ọgbụgbọ
• mkpochapụ izugbe, iro ụra,
• ọsụsọ
• ụjọ, ụjọ
• isi ọwụwa
• ike agụụ
• nhazi nke mmeghari.

Mmalite nke hypoglycemia dị mfe ịhụ. Ihe mbụ ị ga - eme bụ iri ihe dị ụtọ. Maka nke a, ndị na-arịa ọrịa shuga na-ebu swiiti, kuki, mmiri ọ sweetụ sweetụ dị ụtọ ma ọ bụ otu shuga na ha. Ọ bụrụ na ọnọdụ onye ọrịa ahụ kara njọ, ọ nwere ihe mgbu ma ọ bụ nkụda mmụọ, ntụtụ nke glycogen dị mkpa. Ikwesiri ịhụ dọkịta ma dozie usoro nke Actrapid iji gbochie mmepe nke hypoglycemia.

Hyperglycemia mgbe ị na-eji ọgwụ ahụ

Mgbe ụfọdụ ọnọdụ ọzọ kwere omume mgbe shuga dị elu bilitere. Nke a nwere ike ịbụ na mmụba nke okpomoku, yana ọrịa na-efe efe, na mbelata ọgwụ ị orụ ọgwụ ma ọ bụ mmụba nke nri carbohydrate. obughi ikwuputa ya, mana onodu ahu dikwa nsogbu, nihi na enwere ike ibute mmepe nke ketoacidosis na coma. Enwere ike ịkọ eziokwu ahụ shuga abawanye site n'ihe ịrịba ama ndị a:

• oke agu
• ugboro ugboro
• ọgbụgba, agụụ na-agụ,
• adịghị ike
• Akpụkpọ anụ na akpụkpọ anụ mucous,
• isi acetone si n’ọnụ ya.

Ọ bụrụ n’inwere mgbaama ndị a, ị ga-elele ọkwa shuga ozugbo, ịnwere ike ịme ntinye nke Actrapid ọzọ.

Mlọ ọgwụ

Ndụ ọkara nke insulin site n'ọbara ọbara bụ naanị nkeji ole na ole.

Ogologo oge nke ihe insulin na-eme bụ n'ihi nzere, nke dabere na ọtụtụ ihe (dịka ọmụmaatụ, na insulin insulin, usoro na ebe nlekọta, ọkpụrụkpụ nke subcutaneous abụba oyi akwa na ụdị ọrịa shuga mellitus). Yabụ, ọgwụ ọgwụ insulin nke gọọmentị na-enwe mgbanwe dị iche iche na-emetụta mmadụ.

A na-enweta insulin kachasị (C max) na plasma n'ime awa 1.5-2.5 mgbe nchịkwa subcutaneous gasịrị.

O nweghị ihe akpọrọ ihe na-egbochi protein amasara ahụ, ewezuga ọgwụ mgbochi insulin (ọ bụrụ na ọ dị).

A na-ewepụ insulinase mmadụ ma ọ bụ enzymes na-eme ka insulin na-ehichapụ ya, ikekwe site na protein disulfide isomerase.

Echere na na molekul nke insulin mmadu nwere otutu saịtị nke cleavage (hydrolysis), agbanyeghị, ọ nweghị nke metabolites guzobere n'ihi nsachapụ adịghị arụ ọrụ.

Oge nnabata nke ọkara (T ½) kpebisiri ike site na nha iwepu akwara dị n'okpuru ala. Yabụ, T ½ bụ ọkwa nke nnweta, kama ịbụ ihe a na - ewepu insulin na plasma (T ½ nke insulin n'ọbara bụ naanị nkeji ole na ole). Mmụta emere gosiri na T ½ dị ihe dịka awa 2-5.

Childrenmụaka na ndị nọ n'afọ iri na ụma

A mụrụ profaịlụ pharmacokinetic nke Actrapid ® NM na obere ụmụaka nwere ọrịa shuga mellitus (mmadụ 18) ndị dị afọ 6-12, yana ndị na-eto eto (afọ 13-17 afọ). Agbanyeghi na data ndi enwetara bu ihe oke, ha gosiputara na profaịlụ ogwu nke Actrapid ® NM n’ebe umuaka na umuaka di. N'otu oge ahụ, ekpughere ọdịiche dị n’etiti afọ dị iche iche site na ngosipụta dị ka C max, nke na-ekwusi ike ọzọ mkpa nke ịhọrọ otu.

Data Nchekwa nke ime

Na omumu ihe omumu, tinyere akwukwo banyere ogwu ihe banyere ogwu, ihe omumu nke otutu, otutu ihe omumu nke ihe omumu, ihe banyere oria, ma oghaghi ihe ojoo nye ndi mmadu.

Ime na lactation

Enweghị mgbochi ọ bụla na ojiji nke insulin n'oge ime, ebe insulin anaghị agafe ihe mgbochi placental.

Ma ọrịa hypoglycemia na hyperglycemia, nke nwere ike ịmalite n'oge nke usoro ọgwụgwọ ahọpụtaghị nke ọma, na-abawanye ihe ojoo nke arụmọrụ nwa ebu n’afọ na ọnwụ nwa ebu n’afọ. Shouldmụ nwanyị dị ime nwere ọrịa shuga kwesịrị ileba anya n’oge ha dị ime, ha kwesịrị ijikwa ikike nke ọkwa glucose ọbara ka ọ dị mma, otu ndụmọdụ a si emetụta ụmụ nwanyị na-eme atụmatụ ime.

Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.

Mgbe ịmụchara nwa, mkpa insulin dị, dịka iwu, na-alaghachi ọsọ ọsọ na ọkwa a hụrụ tupu ime ime.

Enweghịkwa mmachi iji ọgwụ Actrapid ® NM na-azụ ara. Ingmụrụ nne na-enye nwa ara adịghị ize ndụ nye nwa ahụ. Agbanyeghị, nne nwere ike imezi usoro onunu ogwu nke Actrapid ® NM na / ma ọ bụ nri

Ngwongwo na-agwọ ọrịa

Ọgwụ nwere mmetụta ọgwụgwọ ngwa ngwa, ebe ọ bụ na ọ bụ nke otu ọgwụ ọgwụ nke insulins na-eme ngwa ngwa. Emere ihe eji eme ihe a site na iji teknụzụ bio bioine nke DNA mejuputara site na ntinye nke omenaala nke ndi na-eme bred. Mgbe nchịkwa ọgwụ ahụ mechara nke ọma, ihe ahụ na - arụ ọrụ amalitela iso ndị na - anabata cytoplasmic na - emetụta ụbụrụ. Ihe ahụ na - eme ka usoro dị n'ime sel ahụ pụta site na - akpali biosynthesis nke cAMP, nke na - enye ya ohere ịbanye n'ime oghere n'ime sel.

Dị ka ntụpọ radar si egosi, mbelata ọbara shuga bụ mmụba intracellular mmeghari na nnabata site na anụ ahụ, nke na-eme ka nchekwa nke abụba dịkwuo mma, nchịkọta nke protein protein, glycogenogenesis na-eme, yana mbelata mmepụta glucose site na imeju. Ọgwụ na-amalite imega ahụ niile ọkara elekere mgbe ejiri ya. A na-enweta nsonaazụ kachasị elu mgbe awa 2.5 gachara, oge ngụkọ oge niile bụ ihe dịka awa 7-8.

Mkparịta ụka ọgwụ ọjọọ

Ihe ndị na - eme ka ọ dị mma ịbelata shuga: ọgwụ ọgwụ hypoglycemic, ọgwụ anabolic steroid, androgens, ketoconazole, tetracycline, vitamin B6, bromocriptine, mebendazole, theophylline, ndị na - abụghị ndị na - ahọrọ beta, ihe ọholicụ alcoụ na - egbu egbu, nke na - abụghị naanị ịkwalite mmetụta, mana na-agbatịkwu oge nke ime ihe.

Ọbara shuga dị n’ọbara na-amụba: a na-egbochi ọgwụ mgbochi ọnụ nke ụmụ nwanyị (analogues nke progesterone na estradiol), homonụ thyroid, anticoagulants, clonidine, diazoxide, danazole, tricyclic antidepressants, mgbochi ndị na-egbochi calcium, ọgwụ opioid, nicotinic acid na nicoteroids, Reserpine, salicylates, octreotide, lanreotide na-emetụta arụmọrụ insulin na -aghọta. Ihe ndị a nwere ike ịbelata ma mee ka ọ dịkwuo mkpa ịsụ ọgwụ ahụ.

Thiols na sọlfọ na-enye aka na mbibi ma ọ bụ mmebi nke ọgwụ ọgwụ, na ndị na-egbochi beta na-akpata hypoglycemia ụgha.

Okwu Mmalite

A na-ahapụ ọgwụ nke Subcutaneous, intramuscular na intravenous ọgwụ ahụ. Site na nchịkwa subcutaneous, a na-adụ ndị ọrịa ọdụ ịhọrọ mpaghara apata ụkwụ maka ịgba ọgwụ, ọ bụ ebe a ka ọgwụ ahụ na-edozi nwayọ nwayọ.

Na mgbakwunye, ịnwere ike iji ụkwụ, aka gị na mgbidi ihu nke oghere afọ maka injections (mgbe etinye ya n’ime afọ, mmetụta ọgwụ ahụ ga-amalite ozugbo o kwere omume). Emebela otu mpaghara ugboro ugboro karịa otu ọnwa, ọgwụ ahụ nwere ike kpasuo lipodystrophy.

Ọ bụrụ na ọ dị mkpa ịgbakwunye insulin dị mkpụmkpụ na ogologo, a na-eme algorithm ndị a:

1. A na-ewebata ikuku n'ime ma ampoules (ma ndị dị mkpụmkpụ ma ogologo),
2. Nke izizi, a na-adọrọ insulin ahụ na-adịghị adị obere ke sirinji, mgbe ahụ, ọ na-emeju ọgwụ ọgwụ ogologo oge,
3. A na-ewepụ ikuku site na ịme ọpịpị.

Ọrịa shuga na-enwechaghị ahụmahụ anaghị akwado iwebata Actropide n'ime mpaghara ubu n'onwe ha, ebe enwere nnukwu ihe imepụta abụba na-ezughi oke na ịingụ ọgwụ ahụ intramuscularly. Ọ dị mma ịmara na mgbe ị na-eji agịga ruo 4-5 mm, etinyere abụba subcutaneous ma ọlị.

Amachibidoro itinye ọgwụ ahụ n'ime anụ ahụ gbanwere site na lipodystrophy, yana n'ime hematomas, akàrà, ọnya na ọnya.

Enwere ike ijikwa Actropid site na iji sirinji insulin, otinye sirinji ma ọ bụ mgbapụta akpaka. N'okwu nke abụọ, a na-ewebata ọgwụ ahụ n'ime ahụ n'onwe ya, na abụọ mbụ ọ bara uru ịmara usoro nchịkwa.

• A na-etinye agịga disposer,
• A na-agwakọta ọgwụ ahụ n'ụzọ dị mfe, site n'enyemaka nke onye nkesa ọgwụ 2, a na-ahọrọ ya n'ikuku,
• Iji ngbanwe, a na-edobe uru nke ọgwụ achọrọ,
• Anụ abụba na akpụkpọ ahụ, dịka akọwara ya na usoro gara aga,
• Emeputara ọgwụ a site na ịpị ọkpọ ahụ,
• Mgbe sekọnd iri gasịrị, a na-ewepụ agịga ahụ n’akpụkpọ ahụ, a na-ahapụ opi ahụ.

A gha atụpụ agịga ahụ.

Ọ bụrụ na ejiri ihe eji eme ihe na-adịghị adị oge, ekwesighi ịgwakọta tupu ejiri ya.

Iji wepu nnabata na-ezighi ezi nke ọgwụ yana ịba ụba hypoglycemia, yana hyperglycemia, ekwesighi ịbanye insulin n'ime mpaghara na-ekwesịghị ekwesị na usoro ọgwụgwọ ekwenyeghị na dọkịta ahụ. Amachibidoro iji Actrapid emebiela, ọgwụ nwere ike ibute insulin ókè.

A na-eme nchịkwa ma ọ bụ intramuscularly naanị n'okpuru nlekọta nke dibịa na-aga. A na-ewebata Actrapid n'ime ahụ ọkara elekere tupu nri, nri ga-enwerịrị ike carbohydrates.

NDMỌD:: Ọ ka mma ịbanye insulin n'ụlọ okpomọkụ, yabụ mgbu ga-adị obere.

Kedu ka esi eme Actrapid

Insulin Actrapid bụ otu nke ọgwụ ọgwụ bụ ebumnuche bụ wedata ọkwa shuga dị ala. Ọ bụ ọgwụ na-eme obere oge.

Mbelata shuga bụ:

Ogo ogo ya na ekpughe ya ọgwụ ọgwụ nwere na-adabere na ọtụtụ ihe:

1. Usoro ugwọ nke insulin nkwadebe,
2. Ofzọ nchịkwa (sirinji, mkpịsị sirinji, mgbapụta insulin),
3. Ebe ahọrọ maka nchịkwa ọgwụ (afọ, aka, apata ma ọ bụ isi).

Site na ochichi subcutaneous nke Actrapid, ọgwụ ahụ malitere ime ihe mgbe nkeji iri atọ gachara, ọ rutere n’uche ya kachasị n’arụ mgbe awa 1-3 gachara, dabere n’omume nke onye ọrịa, mmetụta hypoglycemic na-arụ ọrụ ruo elekere asatọ.

Jiri n’oge ime

Anakwere ọgwụgwọ ọgwụgwọ ma ọ bụrụ na ịtụrụ ime nke onye ọrịa. N'ime oge niile, ọ dị mkpa ijikwa ọkwa shuga ma gbanwee usoro ị .ụ ya. Yabụ, n'oge oge ọkara mbụ, mkpa ọgwụ a na-ebelata, n'oge nke abụọ na nke atọ - na iche, ọ na-abawanye.

Mgbe ịmụchara nwa, a chọghachila ịchọrọ insulin etu o si dị tupu ime ime.

N'oge a na-enye nwa ara, mbelata usoro ọgwụgwọ nwere ike ịdị mkpa. Ọrịa dị mkpa iji nlezianya nyochaa ọkwa shuga dị n'ọbara ka ọ ghara ileghara oge oge mkpa ọgwụ ahụ kwụsịrị.

Zụ na nchekwa

Nwere ike ịzụta Actrapid na ụlọ ahịa ọgwụ dịka ọgwụ dọkịta gị nyere gị.

Ọ kachasị mma ịchekwa ọgwụ ahụ na friji n'oge okpomọkụ 2 ruo 7 Celsius. Ekwela ka ekpughere ngwaahịa a ka ọ bụrụ ọkụ ọkụ ma ọ bụ ìhè anyanwụ. Mgbe oyi kpọnwụrụ, Actrapid na-efunyụọ njimara shuga ya.

Tupu ntụtụ ahụ, onye ọrịa ahụ kwesịrị ịchọpụta ụbọchị ọgwụ kwụsịrị, ọ naghị anabata ọgwụ insulin emeela. Gbalia ilele ampoule ma obu vial ya na Actrapid maka sedimenti na ihe ndi ozo si mba ozo.

Ndị ọrịa nwere ụdị 1 na ụdị shuga mellitus abụọ na-eji Actrapid . N'iji ya mee ihe kwesiri ekwesi na onunu ogwu nke dọkịta gosipụtara, o dighi ebute mmepe nke ihe ndi ozo na ahu.

Cheta na ekwesịrị ịgwọ ọrịa shuga n'ụzọ zuru ezu: na mgbakwunye na ọgwụ ị dailyụ ọgwụ kwa ụbọchị, ị ga-agbasosi ụdị nri gị anya, nyochaa mmega ahụ ma ghara ikpughe ahụ ahụ n'ọnọdụ ndị na-akpata nrụgide.

A na-eme ọgwụgwọ nke ndị ọrịa nwere ụdị shuga 1 n'ụdị ọgwụgwọ ọgwụ insulin. Yana mgbochi nri, insulin nchịkwa nwere ike igbochi ndị ọrịa dị otú ahụ ibute ọrịa siri ike nke ọrịa shuga.

Mgbe ị na-edepụta insulin, ọ dị mkpa ịnwale imepụtaghachi nso dị ka o kwere mee na ụda eke nke ịbanye n'ọbara. Maka nke a, a na-enyekarị ndị ọrịa ọgwụ insulin abụọ - ogologo na obere mkpụmkpụ.

Ogologo oge insulins mimic basal (obere na-adịgide adịgide) nzuzo. Edebere obere insulins maka nnabata nke carbohydrates na nri. A na-ahazi ha tupu nri n'ụtụtụ nke kwekọrọ na ọnụ ọgụgụ achịcha dị na ngwaahịa a. Actrapid NM bụ nke ụdị nnụnụ a.