Ọgwụ Diabinax: ntuziaka maka ojiji > Ọgwụgwọ na mgbochi

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	20 mg

PRING microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

10 PC. - blisters (1) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (1) - ngwugwu nke kaadiboodu.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	40 mg

PRING microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

10 PC. - blisters (1) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (1) - ngwugwu nke kaadiboodu.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	80 mg

PRING microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

10 PC. - blisters (1) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (1) - ngwugwu nke kaadiboodu.
10 PC. - blisters (6) - ngwugwu nke kaadiboodu.

Omume ọgwụ

Diabinax bụ ọgwụ hypoglycemic sitere na ọgbọ sulfonylurea II. Ọ na - akpali umeji insulin site na pancreas, na - eme ka insulin na nzuzo nwee mmetụta glucose, ma na - emewanyewanye uru anụ ahụ dị na insulin. Na-akpali ọrụ nke enzymes intracellular - muscle glycogen synthetase. Na -ebe oge site na oge iri nri rue mmalite insulin insulin. Ọ na-eweghachi ọkwa mbụ nke insulin insulin (n'adịghị ka ihe ndị ọzọ sitere na sulfonylurea, dịka ọmụmaatụ, glibenclamide na chlorpropamide, nke metụtara tumadi n'oge ọkwa nke abụọ nke nzuzo). Na-ebelata oke hyperglycemia mgbe ị risịrị nri.

Na mgbakwunye na emetụta metabolism metabolism, ọ na-emetụta microcirculation. Na-ebelata oke hyperglycemia mgbe ị risịrị nri. Na-ebelata platelet na nchịkọta, na-ebelata mmepe nke thrombus mgbidi. Ọ na - eme ka ọghọm nke akwara ghara imebi, na - egbochi mmepe nke microthrombosis, na - eweghachite usoro physiological parietal fibrinolysis.

Na-ebelata akwara vaskụla na adrenaline. Ọ nwere ihe anti-atherogenic, na-ebelata ịta nke cholesterol n'ime ọbara.

Na-eme ka mmepe nke ọrịa mamịrị nke ọrịa mamịrị na -akwụkọ nke ukwuu. Site na nephropathy ọrịa mamịrị na iji ogologo oge, enwere nnukwu mbelata na proteinuria.

Ọ naghị ebute mmụba n’arụ ahụ, n’ihi ọ nwere mmetụta kachasị ukwuu na mmalite nke insulin insulin ma ghara ịkpata hyperinsulinemia, na-enyere aka belata oke ahụ n'ahụ ndị ọrịa buru ibu, na-agbaso nri kwesịrị ekwesị.

Mlọ ọgwụ

Mgbe a na -ewere ya ọnụ, a na-etinye ọgwụ ahụ nke ọma na ngọngọ nri. C max na plasma ọbara ruru ihe ruru awa anọ mgbe ị aụchara otu ọgwụ were 80 mg. Njikọ protein protein Plasma bụ 94%. Ọ bụ metabolized n'ime imeju na -emepụta ọtụtụ metabolites. Ọ kpụrụ ya akụrụ - 70% n'ụdị metabolites, ihe na-erughị 1% dị na mmamịrị na-agbanwe agbanwe, yana ọrịa ahụ - 12% n'ụdị metabolites. T 1/2 - ihe dị ka awa iri na abụọ

Usoro onunu ogwu nke DIABINAX

Ọtọ ọgwụ a n’otu n’otu, dabere n’afọ onye ọrịa, ngosipụta nke ọrịa ahụ na ọkwa nke glycemia na-ebu ọnụ na mgbe awa 2 gachara. Ọgwụ mbụ kwa ụbọchị bụ 80 mg, nkezi kwa ụbọchị bụ 160 mg, yana kacha ụbọchị kwa ụbọchị bụ 320 mg. A na -ebu Diabinax ugboro abụọ / ụbọchị (ụtụtụ na mgbede) nkeji 30-60 tupu nri.

Mkparịta ụka ọgwụ ọjọọ

Sulfanilamides, salicylates, anticoagulants na-apụtakarị, ọgwụ anabolic steroid, beta-blockers, fibrates, chloramphenicol, phenfluramine, fluoxetine, guanethidine, MAO inhibitors, pentoxifylline, theophylline, caffeine, phenylbutazone, tlinecycline tlinecycline na tlinecycline na tlinecycline tlinecycline

N'iji oge nke gliclazide na acarbose, ana-ahụ mmetụta hypoglycemic na-agbakwunye, nke chọrọ mmezi nke ọgwụ ndị a.

Cimetidine na-eme ka ịbawanye ụba nke gliclazide na plasma ọbara, nke nwere ike ibute hypoglycemia dị ukwuu (ịda mbà CNS, adịghịzi emetụta), yabụ, a naghị atụ aro ijikọta ọgwụ ndị a.

Barbiturates, chlorpromazine, glucocorticosteroids, sympathomimetics, glucagon, nicotinic acid, estrogens, progesins, ọgwụ mgbochi, diuretics, rifampicin, homonụ thyroid, nnu nke lithium na-ebelata ike hypoglycemic nke glyclazide.

Inwe ojiji nke gliclazide na imerizole imerizo (gụnyere miconazole).

Mpempe ntọhapụ, nkwakọ ngwaahịa na ihe mejupụtara Diabinax

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	20 mg

Ndị pụrụ iche: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (3) - ngwugwu nke kaadiboodu.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	40 mg

Ndị pụrụ iche: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (3) - ngwugwu nke kaadiboodu.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide	80 mg

Ndị pụrụ iche: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (3) - ngwugwu nke kaadiboodu.

DIABINAX - nsonaazụ

Site na usoro endocrine: hypoglycemia (yana ị anụbiga mmanya ókè na / ma ọ bụ nri ezughị ezu).

Mmeghachi omume nfụkasị: ọnya anụ ahụ, urticaria, pruritus.

Site na usoro digestive: adịkarịghị - anorexia, ọgbụgbọ, vomiting, afọ ọsịsa, mmetụta nke oke ma ọ bụ ihe mgbu na mpaghara epigastric.

Site na sistemụ hemopoietic: thrombocytopenia, leukopenia ma ọ bụ agranulocytosis, anaemia (a na-atụgharịkarị).

Ntụziaka pụrụ iche maka iwere DIABINAX

A na-eme ọgwụgwọ Diabinax yana nri nwere obere kalori.

N'oge ọgwụgwọ, ị kwesịrị ị na-enyocha ọkwa nke ibu glycemia na mgbe ị risịrị nri.

Iji nlezianya kpachara anya, a ga-eji ọgwụ ahụ mee ihe na ndị ọrịa na-arịa ụkọ adrenal, ọrịa nke gland thyroid (yana ọrụ na-arụ ọrụ), pyelonephritis na-adịghị ala ala, na ahoụrụma.

N'ibute mmerụ ahụ dị ukwuu, ọrịa na-efe efe, ịwa ahụ, a ga-atụle ohere nke iji insulin kwadebe ya.

Imeghari otu ọ̀ dị mkpa maka ịghara oke nri anụ ahụ na nke mmetụta uche, mgbanwe nri.

N'ọnọdụ ọnụ ma ọ bụ alcoholụọ mmanya, ohere ịba ụba hypoglycemia na-abawanye.

Mmetụta ikike ịkwọ ụgbọ ala na usoro nchịkwa

N'oge ọgwụgwọ, a naghị atụ aro ka ị na-eme ihe ndị chọrọ ntinye anya na nzaghachi ngwa ngwa.

Ihe ngbanwe

Ọrịa hyperensitivity, ụdị ọrịa shuga mellitus 1, ọrịa shuga, prepoa shuga na coma, nnukwu ịba ọcha n'anya na / ma ọ bụ akụrụ gbasara afọ ime, ime, ịgba nwa, n'okpuru afọ 18. 18kpachara anya. Ọnọdụ na-adakarị ọrịa na-achọkarị nlekọta insulin (nnukwu ihe ịwa ahụ na mmerụ ahụ, oke ọkụ, ọrịa na-efe efe na ọrịa febrile), ịhoụbiga mmanya ókè, ịka nká.

Etu esi eji: usoro onunu ogwu na usoro ọgwụgwọ

N'ime, n'oge nri, usoro mbụ kwa ụbọchị bụ 80 mg, nkezi nkezi kwa ụbọchị bụ 160-320 mg (maka 2 onunu, n'ụtụtụ na mgbede). Ọgwụ a na-adabere na afọ, ogo nke ọrịa shuga, ịta nke glucose ọbara na-ebu ọnụ na awa 2 mgbe ị risịrị nri.

A na-ewere mbadamba 30 mg agbanwe mbadamba otu ugboro kwa ụbọchị na nri ụtụtụ. Ọ bụrụ na ọgwụ ahụ funahụrụ ya, yabụ echi ya ekwesịghị ịba ụba ọgwụ a. Usoro ọgwụgwọ akwadoro nke mbụ bụ mg mg 30 (gụnyere maka ndị ruru 65). Enwere ike ịgbanwe mgbanwe ọ bụla na - esote izu ma ọ dịkarịa ala izu abụọ. Dosebọchị kwa ụbọchị ekwesịghị ịfe 120 mg. Ọ bụrụ na onye ọrịa enwetara ọgwụgwọ na sulfonylureas nwere ogologo T1 / 2 (dịka ọmụmaatụ, chlorpropamide), iji nlezianya nyochaa (1-2 izu) dị mkpa iji zere hypoglycemia n'ihi nsonaazụ nke mmetụta ha.

Usoro usoro ọgwụgwọ maka ndị ọrịa agadi ma ọ bụ na ndị ọrịa nwere obere mkpesa na-adịghị ala ala (CC 15-80 / min) bụ otu ihe ahụ dị n'elu.

Na insulin, a na-atụ aro mg 60-180 ka ụbọchị dum.

Releasedị Diabinax, nkwakọ ngwaahịa ọgwụ na ihe mejupụtara.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

Taabụ 1
gliclazide
20 mg
-«-
40 mg
-«-
80 mg

Ndị ọkachamara: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu.
20 nkp. - blisters (3) - ngwugwu nke kaadiboodu.

NWAANYI NIILE ANYA.
A na-egosi ozi niile enyere naanị maka ịmara ọgwụ ahụ, ị kwesịrị ịkpọtụrụ dọkịta maka ohere eji ya.

Mmetụta dị n'akụkụ Diabinax:

Site na usoro digestive: adịkarịghị - anorexia, ọgbụgbọ, vomiting, afọ ọsịsa, mgbu epigastric.

Site na usoro hemopoietic: n'ọnọdụ ụfọdụ - thrombocytopenia, agranulocytosis ma ọ bụ leukopenia, anaemia (nke a na-atụgharịkarị).

Site na usoro endocrine: na ị anụbiga mmanya ókè - hypoglycemia.

Mmeghachi omume nfụkasị: ọnya anụ ahụ, itching.

Ntụziaka pụrụ iche maka iji Diabinax.

A na-eji Gliclazide gwọọ ọrịa mellitus na-abụghị insulin na-etinye ya na obere kalori, nri nwere obere carb.

N'oge ọgwụgwọ, ị kwesịrị ị na-enyocha ọkwa nke glucose n'ọbara na afọ na-enweghị nri na mgbe ị risịrị nri, na-agbanwe kwa ụbọchị na ọkwa glucose.

N'ihe banyere usoro ịwa ahụ ma ọ bụ mejupụta ọrịa shuga mellitus, ọ dị mkpa ịtụle ohere iji insulin insulin mee.

Site na mmepe nke hypoglycemia, ọ bụrụ na onye ọrịa maara, a na-edenye glucose (ma ọ bụ ihe ngwọta shuga) n'ime. Ọ bụrụ na mmụọ amaghị, a na-edozi glucose intravenous ma ọ bụ glucagon sc, intramuscularly ma ọ bụ intraven. Mgbe ọ nwetasịrị, ọ dị mkpa inye onye ọrịa ahụ nri nwere carbohydrates iji zere ịmaliteghachi hypoglycemia.

N'iji oge nke gliclazide na verapamil, a na-achọ nlezianya nke ọkwa glucose ọbara, yana acarbose, jiri nlezianya na-agbazi ma na-agbazi usoro ọgwụgwọ usoro nke ndị na-ahụ ike hypoglycemic si chọọ.

Ekwesighi iji gliclazide na cimetidine n'otu oge.

Nmekorita nke Diabinax ya na ogwu ndi ozo.

Mmetụta hypoglycemic nke gliclazide bụ nke a na-eji ya eme ihe na iji ya eme ihe na pyrazolone, salicylates, phenylbutazone, antibacterial sulfonamide ọgwụ, theophylline, caffeine, MAO inhibitors.

Ojiji nke beta-egbochi na-eme ka enwee ike ịbawanye hypoglycemia, ọ nwekwara ike ikpuchi tachycardia na ịma jijiji aka, njirimara nke hypoglycemia, ebe ịchafụ nwere ike ịba ụba.

N'iji oge nke gliclazide na acarbose, a na-ahụ mmetụta hypoglycemic na-eme ihe.

Cimetidine na-eme ka ịbawanye ụba nke gliclazide na plasma, nke nwere ike ibute nnukwu hypoglycemia (ịda mbà CNS, nsụhọ mmụọ).

Site na iji GCS n'otu oge (gụnyere usoro onunu ogwu maka iji mpụga), diuretics, barbiturates, estrogens, progesins, ọgwụ estrogen-progestogen jikọtara ọnụ, diphenin, rifampicin, mmetụta hypoglycemic nke glyclazide belatara.

Nsonaazụ

Ọrịa hypoglycemia (nke mebiri usoro ịsingụ mmiri na nri na-ezighi ezi): isi ọwụwa, ịda mba, agụụ, ịsụsọ na-aba ụba, ike ọgwụgwụ, ahụ ike, iro ụra, oke iwe, oke iwe, nchekasị, iwe, enweghị nchekasị, enweghị ike itinye uche n'ihe na igbu oge. nkwarụ anya, aphasia, shoor, paresis, nsogbu uche, nkụda mmụọ, mmetụta nke enweghị enyemaka, ọnwụ nke njide onwe onye, nchekasị ahụ, ihe mgbu, hyperomnia, nsụhọ, iku ume, imi dicardia.

Site na usoro nri: dyspepsia (ọgbụgbọ, afọ ọsịsa, mmetụta nke oke na epigastrium), agụụ ririlata - ogo na-ebelata nri, adịkarịghị - nsị imeju (cholestatic jaundice, ụba ọrụ nke transminases "imeju").

Site na akụkụ ahụ na hemopoietic: mgbochi nke ụmị ọkpụkpụ (anaemia, thrombocytopenia, leukopenia).

Mmeghachi omume nfụkasị ahụ: itching, urticaria, flop na maculopapular.

Ihe ozo: mgbakasị ahụ nke akpụkpọ ahụ na mucous akpụkpọ ahụ overdose. Mgbaàmà: hypoglycemia, nsụhọ nke uche, hypoglycemic coma.

Ọgwụgwọ: ọ bụrụ na onye ọrịa maara, were shuga n'ime, yana nsogbu nke nsụhọ - na / na ntinye nke hypertonic dextrose solution (40%), 1-2 mg nke glucagon / m, ịchịkwa mgbanye glucose ọbara kwa nkeji 15, yana mkpebi siri ike nke pH, urea, creatinine, na ọbara electrolytes. Mgbe ọ nwetasịrị, ọ dị mkpa inye onye ọrịa ahụ nri nwere nnukwu carbohydrates na-adị ngwa ngwa (iji zere ịmalite ịmalite hypoglycemia). Na ọrịa ụbụrụ, mannitol na dexamethasone.

Leasedị ntọhapụ, ihe mejupụtara na nkwakọ

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

	Taabụ 1
gliclazide	20 mg

Ndị ọkachamara: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu. - blisters (3) - ngwugwu nke kaadiboodu.

Mbadamba nkume ndị ahụ dị ọcha, gburugburu, dị larịị, nwere mpe mpe mpekere na ahịrị nke dị n'otu akụkụ.

	Taabụ 1
gliclazide	40 mg

Ndị ọkachamara: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu 20 pcs. - blisters (3) - ngwugwu nke kaadiboodu.

Mbadamba ndị ahụ na-acha ọcha, gburugburu, ewepụghị, nwere akụkụ gbara agba na eriri na-adịghị mma n'otu akụkụ.

	Taabụ 1
gliclazide	80 mg

Ndị ọkachamara: microcrystalline cellulose, stachi, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium starch glycolate, talc, mmiri dị ọcha.

20 nkp. - blisters (2) - ngwugwu nke kaadiboodu. - blisters (3) - ngwugwu nke kaadiboodu.

Ngwakọta na ụdị ntọhapụ

Otu mbadamba 1 nwere 20, 40 ma ọ bụ 80 mg glycoslide, yana excipients (MCC, stachi, povidone, sodium methyl paraben, colloidal silicon dioxide / aerosil, magnesium stearate, sodium sitashi glycolate, talc, mmiri dị ọcha), na ngwugwu blister 10 pcs. ., n'ime ngwugwu kaadiboodu 6.

Usoro onunu ogwu na nhazi

N'ime, nkeji 30-60 tupu nri ugboro 2 n'ụbọchị (n'ụtụtụ na mgbede).A na-ahọrọ ọgwụ ahụ n'otu n'otu, dabere na afọ onye ọrịa, ngosipụta nke ọrịa na ọkwa nke glycemia na-ebu ọnụ na awa 2 mgbe iri nri. Ọtụtụ mgbe, usoro mbụ kwa ụbọchị bụ 80 mg, nkezi bụ 160 mg / ụbọchị, ihe kachasị bụ 320 mg / ụbọchị.

Diabinax shelf ọgwụ ndụ

Ejila oge ngwụcha ụbọchị egosipụta na ngwugwu ahụ.

Hapụ okwu gị

Nchọpụta Ozi Ugbu A, ‰

Aha ọgwụ dị mkpa yana ọgwụ ndị dị mkpa

Asambodo ndenye aha Diabinax

P N014190 / 01

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Anaghị anabata iji ihe azụmaahịa.

Ezubere ozi a maka ndị ọrụ ahụike.

DIABINAX: DOSAGE

Ọtọ ọgwụ a n’otu n’otu, dabere n’afọ onye ọrịa, ngosipụta nke ọrịa ahụ na ọkwa nke glycemia na-ebu ọnụ na mgbe awa 2 gachara. Ọgwụ mbụ kwa ụbọchị bụ 80 mg, nkezi ụbọchị kwa ụbọchị bụ 160 mg, yana kacha ụbọchị kwa ụbọchị bụ 320 mg. A na -ebu Diabinax ugboro abụọ / ụbọchị (ụtụtụ na mgbede) nkeji 30-60 tupu nri.

Dodoụbiga ya ókè

Mgbaàmà: pallor nke anụ ahụ, tachycardia, agụụ, ọsụsọ na-aba ụba, ịma jijiji, n'ọnọdụ ndị siri ike - mmụọ adịghị mma.

Ọgwụgwọ: ọ bụrụ na onye ọrịa maara, glucose ma ọ bụ mmiri shuga bụ nke ọnụ ka edepụtara. Ọ bụrụ na mmụọ amaghị, a na-edozi 40% glucose ma ọ bụ glucagon s / c, i / m, i / v na-achịkwa iv. Mgbe ọ nwetasịrị, ọ dị mkpa inye onye ọrịa ahụ nri nwere carbohydrates iji zere ịmaliteghachi hypoglycemia.