Ihe mgbochi megide iji Mikardis, usoro nke ime ihe, ihe ngosi, mmekorita ya, mmetụta na ntuziaka maka ojiji

Mlọ ọgwụ Telmisartan bụ onye antagonistin II receptor antagonist a kapịrị ọnụ ma dị irè (ụdị AT1). Telmisartan, nwere ezigbo ogo mmekọrịta, dochie angiotensin II na saịtị ya jikọtara ndị na-anabata ndị na-anabata AT1, bụ ndị na-ahụ maka mmetụta physiological nke angiotensin II. Telmisartan anaghị egosipụta oke ọrụ agonistic megide ndị na-anabata AT1. Ekwekọrịtara onye na-anabata ya, akọwapụtara ya ogologo. Telmisartan enweghị mmekọrịta maka ndị na-anabata ndị ọzọ, gụnyere AT2 na ndị na-anabata ndị ọzọ AT. Achọpụtaghị ọrụ dị mma nke ndị na-anabata ndị a, dị ka mmetụta nke ike ịmebiga ha ókè site na angiotensin II, ekpughebeghị ọkwa nke telmisartan. Telmisartan na-ebelata ọkwa plasma aldosterone, ọ naghị emetụta ọrụ plasma renin, anaghị egbochi ọwa ion, anaghị egbochi ACE (kininase II), enzyme nke na-akụda bradykinin. Ya mere, ị theụ ọgwụ ahụ esoghịkwa nsonaazụ ndị metụtara nsụkọ bradykinin.
Mgbe ewere ya na 80 mg, telmisartan fọrọ nke nta ka ọ gbochie mmetụta ọbara mgbali elu nke angiotensin II, mmetụta akpọrọ antihypertensive na-adịgide ruo awa 24 ma na-adịgide ruo 48 awa.
Mgbe ị theụsịrị ọgwụ mbụ nke telmisartan, mmetụta antihypertensive na-amalite nwayọọ nwayọọ karịa awa 3, mmetụta hypotensive kachasị na-ebido izu 4-8 mgbe mmalite nke ọgwụgwọ ma nọgide na-eji ọgwụ ogologo oge. Mmetụta antihypertensive na-anọgide na ọkwa mgbe niile ruo awa 24 mgbe nchịkwa gasịrị, gụnyere gụnyere awa anọ gara aga tupu nchịkwa ọzọ. Ekwenyere nke a site na nlele anya nke ọbara mgbali.
N'ime ndị ọrịa nwere ọbara mgbali elu (akwara ọbara), telmisartan na-ebelata ma ọbara systolic na diastolic ọbara na-enweghị emetụta mmetụ obi. Site na ịwepụ ọgwụ ahụ na mberede, ọkwa ọbara mgbali ji nwayọ laghachi ọkwa mbụ na-enweghị mmepe nke ọrịa mwepụ.
Ọmụmụ nyocha nke ụlọ ọgwụ ekwenyela na ọgwụgwọ na telmisartan belatara belata ventricular myocardial mass na ekpe ventricular myocardial mass na ndị ọrịa nwere ọbara mgbali elu (mgbali elu) yana mgbali elu ventricular myocardial.
N'ime ọmụmụ ụlọ ọgwụ, achọpụtara na telmisartan yikarịrị ka ndị na-egbochi ACE na-akpata mmepe nke ụkwara akọrọ.
Mlọ ọgwụ Gbasara ngwa ngwa mgbe nchịkwa ọnụ gasịrị, nkezi bioavailability zuru oke bụ ihe dịka 50%. Ọ bụrụ na ejiri ọgwụ ahụ were nri, mbelata na AUC dị iche na 6% (mgbe ewere ya na 40 mg) na 19% (mgbe ewere ya na 160 mg). Mgbe awa atọ gachara ị theụ ọgwụ ahụ, ịta ọbara na plasma ọbara ahụ kwụsiri ike ma ọ dabaghị na ma a kpọgara Telmisartan na afọ efu ma ọ bụ na nri.
A na-ejikọkarị Telmisartan na protein plasma (99.5%), tumadi ya na albumin na glycoprotein alpha-1-acid. Olu nke ikesa n’usoro izizi di 500 lita. A na-agbanye Telmisartan site na conjugation na glucuronide. Na conjugate enweghị ọrụ ọgwụ. A kọwara Telmisartan site na profaịlụ ọgwụ Biexponential nke nwere ọkara ndụ na ọdụ ụgbọ ihe karịrị awa 20. Oke ịba ụba na plasma ọbara na AUC na-abawanye nke ukwuu na dose ahụ. Onweghi ihe akaebe banyere imubanye akwara di egwu n’ahu mgbe ejiri ya were mee ya. Ngwakọta plasma dị na ụmụ nwanyị karịrị nke ụmụ nwoke, na-agbanweghị arụmọrụ.
Mgbe nchịkwa ọnụ gachara, telmisartan fọrọ nke nta ka ọ bụrụ na feces, anaghị abụkarị agbanwe agbanwe, urinary excretion erughị 2% nke dose. Mkpokọta mkpụkọ ọbara plasma dị elu (ihe dị ka 900 ml / min), ma e jiri ya tụnyere ọbara ọwụwa hepatic (ihe dị ka 1500 ml / min).
Otu ndị ọrịa pụrụ iche
Ndị okenye na-arịa ọrịa
Lọ ọgwụ ọgwụ telmisartan n'ime ndị agadi adịghị iche na nke ndị okenye.
Ndị ọrịa nwere ọrụ mgbazinye nsogbu
N'ime ndị ọrịa nwere ọrịa akụrụ na -eche onyocha akwara, a na-ahụkarị ọkwa plasma nke telmisartan, mana nke a enweghị ihe gbasara ọgwụgwọ. Telmisartan nwere ogo dị ukwuu na-egbochi protein ndị dị na plasma, yabụ, ọ fọdụchaghị ya n'oge a na-ahụ ya.
Ndị ọrịa nwere ọria imeju
N'ime ndị ọrịa nwere ọrụ imeju na-adịghị mma, bioavailability na-abawanye ruo 100%.

Mwepụta wepụtara ya na ihe mejupụtara

Sdị usoro onunu ogwu - mbadamba: oblong, ihe fọrọ nke nta ka ọ bụrụ ọcha ma ọ bụ na-acha ọcha, n'otu akụkụ - na-ese "51N" (mbadamba 40 mg) ma ọ bụ "52H" (mbadamba 80 mg), na nke ọzọ - akara nke ụlọ ọrụ (pcs 7. n'ime igbe kaadi 2 ma ọ bụ 4 nke nwere mbadamba 40 mg ma ọ bụ blister 2, 4 ma ọ bụ 8 nwere mbadamba 80 mg na ntuziaka maka iji Mikardis).

Ngwakọta ọrụ: telmisartan, ọdịnaya ya na mbadamba 1 bụ 40 ma ọ bụ 80 mg.

Ndị ọkachamara: sodium hydroxide, polyvidone (collidone 25), sorbitol, meglumine, magnesium stearate.

Mlọ ọgwụ

Ihe mejupụtara nke Mikardis - telmisartan, bụ ihe na - emegidekarị ndị nnabata angiotensin II. Egosiputara site na ezi enyi maka AT subpepe₁ndị na-anabata angiotensin II, site na nke omume nke angiotensin II. Telmisartan anaghị enwe mmetụta agonistic na angiotensin nke II ma chụpụ ya site na njikọta nke onye na-anabata ya, na njikọ ahụ na-etinyere naanị na mpaghara AT.₁ndị na-anabata angiotensin nke abụọ, ebe njikọ ahụ na-adịgide.

Ọgwụ ahụ enweghị mmekọrịta maka ndị na-anabata angiotensin ndị ọzọ, gụnyere AT subtype₂. Agụbeghị uru ọrụ ha na nsonaazụ nke mkpali na angiotensin nke abụọ, amụchaghị nke telmisartan.

Telmisartan na -ebelata mkpụkọ aldosterone n'ọbara. Ọ naghị egbochi ọtụ ion ma ọ dịghị egbochi mgbochi nke plasma ọbara. Ọ naghị egbochi kininase nke abụọ (enzyme angiotensin) na enzyme nke nwekwara ikike ibibi ihe megide bradykinin, yabụ, atụghị anya mmụba nke mmetụta nke bradykinin kpatara.

Mgbe ewere ya na 80 mg, telmisartan na-egbochi mmetụta ọbara mgbali elu nke angiotensin II. A na-ahụta mmetụta nke ọgwụ ahụ n'ime awa 3 mgbe ọgwụ mbụ gasịrị, ọ na-adịgide ruo awa 24 ma na-adịgide ruo ihe dị ka awa 48. Mmetụta ọgwụ antihypertensive na-amalite mgbe izu 4-8 nke iji Mikardis na-aga n'ihu.

N'ime ndị ọrịa nwere ọbara mgbali elu, Mikardis na-ebelata diastolic na ọbara mgbali systolic, mana ọ naghị emetụta ọnụego obi.

Mgbe akagbuola telmisartan na mberede, ndị na - egosi ọbara mgbali jiri nwayọ laghachi ọkwa mbụ ha, nke na - esite na mmepe nke ọrịa mwepu.

Mlọ ọgwụ

A na-etinye Telmisartan ngwa ngwa site na eriri afọ site na nchịkwa ọnụ nke Mikardis. Ya bioavailability bụ 50%. N'ihe banyere iri nri otu oge, uru nke AUC na-agbada (mpaghara dị n'okpuru usoro nlebara anya): ihe ngosi egosi sitere na 6% (na ọnụọgụ nke telmisartan 40 mg) ruo 19% (na dose 160 mg). Mgbe awa atọ gachara Mikardis, ọgwụ ịta ahụ na plasma na-agbasa n'agbanyeghi oge ewere nri ahụ.

Ihe e ji mara Telmisartan bụ nnukwu ihe metụtara protein protein (ọkachasị albumin na alfa)₁- glycoprotein) - karịa 99.5%.Olu doro anya nke ekesara nha anya ruru ihe ruru 500 l.

A na-eme ka ọgwụ ahụ mejupụta ọgwụ glucuronic acid site na conjugation, n'ihi nke a na-emepụta ọgwụ metabolites na-adịghị arụ ọrụ. Ọ bụpịrị ya site na eriri afọ n'ụdị agbanweghi, ihe na-erughị 2% nke dose ahụ bụ akụrụ ga-apụ.

Mwepu ọkara ndụ gafere karịa awa 20. Mkpochapụ plasma bụ 900 ml / min, ọbara ịba ọcha n'anya bụ 1500 ml / min.

Pharmacokinetics n'okwu ikpe gbasara ọrịa:

• okike: n'ime ụmụ nwanyị, ntinye uche kachasị na AUC dị elu karịa na ụmụ nwoke, ihe dịka ugboro atọ na ugboro abụọ, n'otu n'otu, ebe enweghị nnukwu ọdịiche dị na arụmọrụ Mikardis,
• ịka nká: ọgwụ pharmacokinetic na ndị ọrịa agadi adịghị iche na ndị ọrịa na-eto eto, ya mere, a chọghị mgbanwe mgbanwe dose,
• afọ ụmụaka site na afọ isii ruo afọ iri na asatọ: mgbe ị na-etinye Mikardis n'ọtụtụ 1 mg / n'arọ ma ọ bụ 2 mg / n'arọ maka izu anọ, ọgwụ pharmacokinetics nke telmisartan yiri nke ndị toro eto, nke na-egosi na enweghị linearity nke pharmacokinetics nke ihe ahụ, ọkachasị metụtara oke ịta,
• odida akwara na usoro ịba uru: akparamagwa nke telmisartan anaghị agbanwe, yabụ ndozi ọgwụ adịghị achọrọ. Ogwu n’enyeghi aka na iwepu ogwu n’anu ahu,
• obere ịba ọcha n'anya na-agafe agafe (Childmụaka Pugh na A na B): ọgwụ kwa ụbọchị nke telmisartan ekwesịghị gafere 40 mg.

Ihe ngbanwe

• Nleghara nke fructose anabataghị (n'ihi sorbitol ọdịnaya),
• Ọkpụkpụ na-arụ ọrụ imeju (klas C dị ka ọnụ ọgụgụ ụmụaka-Pugh)
• Ọrịa na-egbochi ọnya biliary
• Primary aldosteronism,
• N’agbata afọ 18
• Ime na lactation
• Akpachapụ anya na akụkụ nke mbadamba Mikardis.

• Hyperkalemia
• Hyponatremia,
• Obi akwara obi (CHD),
• Ọrịa obi na-adịghị ala ala
• Idiopathic hypertrophic subaortic stenosis,
• Stenosis nke aortic na valvụ valve,
• Mbelata ọbara n’arịa n'ihi afọ ọsịsa ma ọ bụ ọgbụgbọ, amachibido nnabata nnu na / ma ọ bụ ọgwụgwọ ụgwụ nke gara aga,
• Imeju na arụ ọrụ akụrụ arụ,
• Stenosis akwara klaasị ma ọ bụ stenosis nke otu akụrụ
• Ọnọdụ mgbe akụrụ gbasara akụrụ.

Nkọwa nke usoro eji eme ihe: pharmacodynamics na pharmacokinetics

A na - etolite Angiotensin II site na angiotensin nke m nọ n'okpuru ikike nke angiotensin na - agbanwe enzyme (ACE). Homonụ nke Vasoactive na-emetụta ọbara mgbali site na ndị na-anabata AT1. Angiotensin II na - ebute vasoconstriction ma na - eme ka ọkwa nke sistemụ ọmịiko na - abawanye, nke na - eduga n'ịba ụba nke sodium reabsorption na akụrụ na nzuzo aldosterone na gland adrenal.

Onye nnabata AT1

Telmisartan, dị ka usoro antagonensin II ndị ọzọ na-anabata antagonist, bụ usoro benzimidazole. Ọ na - egbochi ụdị 1 angiotensin ndị na - anabata ya ma na - wedata ọbara mgbali elu.

A na-etinye Telmisartan ngwa ngwa. Oke plasma dịkarịsịrị na-adị ma elekere 1 gachaa. Ọgwụ na-eme metabolism nke usoro. Bioavailability bụ ọgwụ dabere na oke sitere na 40 ruo 60%. N'otu oge, nri nwere ike belata iwere ọgwụ. A na-ejikọ Telmisartan na glucuronic acid ma wepu ya site na bile na stool. Ọkara ọkara bụ ihe dịka awa iri abụọ na anọ. Enwere ike ịnweta ozi ndị ọzọ gbasara ọgwụ na ọnụ ahịa na aha ọgwụ (RLS).

Ọmụmụ nyocha ahụike

E jiri Telmisartan tụnyere placebo na ọgwụ mgbochi ọgwụ ndị ọzọ. Ọtụtụ ọmụmụ nwoke gụnyere ụmụ nwoke na ụmụ nwanyị nọ n'afọ ndụ niile. N'ime ihe omumu abuo a na - ejikwa ogwu na - egbochi telmisartan. N'ime oke site na 20 ruo 80 mg / ụbọchị, ọgwụ ahụ belatara nrụgide. Karịrị 80 mg / ụbọchị, mmetụta ahụ amụtaghị, agbanyeghị, nsonaazụ ndị dị mkpa.

Na omumu omumu abuo, ndi mmadu 385 natara telmisartan na ndi mmadu 193 natara lisinopril. Ọgwụ izizi maka telmisartan bụ 40 mg / ụbọchị otu ugboro na 10 mg / ụbọchị maka lisinopril. Ọ bụrụ na ọbara ọgbụgba diastolic adaghị n'okpuru 90 mmHg ka izu anọ gachara, ọnụọgụ abụọ ahụ okpukpu abụọ. Mgbe ahụ ndị ọrịa gara n'ihu na-a doseụ ọgwụ enyere maka izu 48. Telmisartan monotherapy zuru ezu na 44% nke ikpe. Obara mgbali belatara jiri mgbada 18/16 mm Hg. Maka lisinopril, ọnụ ọgụgụ kwekọrọ bụ 48% na 19/16 mm Hg. Na njikọta hydrochlorothiazide, telmisartan belatara mgbali ọbara site 2 mmHg. Art. karịa lisinopril.

Hydrochlorothiazide

Dabere na atụmatụ yiri nke ahụ, e jiri telmisartan tụnyere enalapril ọnwa isii. Ọmụmụ ihe metụtara mmadụ 272 bụ ndị dịkarịa afọ 65. Ọgwụ nke telmisartan sitere na 40 ruo 80 mg, na enalapril - site na 1 ruo 5-20 mg kwa ụbọchị. Ihe abuo ndi ahu gosiputara uto antihypertensive.

N'ime ọmụmụ ihe mkpị nwere nku abụọ maka izu isii, ndị ọrịa 222 natara placebo, telmisartan (40 ma ọ bụ 80 mg / ụbọchị otu ugboro), ma ọ bụ losartan. Nkeji mgbada n'ọbara bụ 14/9 mm Hg. (40 mg / ụbọchị) ma ọ bụ 16/10 mmHg mgbe ị na-eji telmisartan.

Ndị ọrịa 232 natara telmisartan (40-120 mg / ụbọchị), amlodipine (5-10 mg / ụbọchị), ma ọ bụ placebo maka izu iri na abụọ. E bu ụzọ depụta ọgwụ mgbochi abụọ ka ọ dịkarịa ala. Ọ bụrụ n’ọbara ọbara ọgbụgba ahụ agbadaghị nke ọma, a mụbaara ọgwụ ahụ. Ọbara ọbara belatara site na nkezi nke 17/12 na telmisartan na 18/12 mm Hg. ya na amlodipine. N'ime otu telmisartan, usoro izizi ezughi oke. N'ime ìgwè amlodipine, naanị 40% nke ndị ọrịa nwere usoro ọgwụ ha. Ọzọkwa n'ọmụmụ ihe a, achọpụtara na mkpụrụ nke telmisartan karịa 80 mg / ụbọchị nwere obere ọgwụ antihypertensive ọzọ.

Dabere na otu nnyocha, telmisartan na-eme otu ihe ahụ ma atenolol (1 oge site na 50 ruo 100 mg / ụbọchị). Na nyocha ụfọdụ, a na-enyocha ụfọdụ ndị ọrịa awa iri abụọ na anọ. Achọpụtara ya na telmisartan nwere mmetụta antihypertensive dị mma karịa ihe ndị nwere obere ndụ (dịka ọmụmaatụ, losartan). Agbanyeghị, e jiri ya tụnyere enalapril, enweghị ọdịiche ọ bụla. N'ime nnyocha mepere emepe, achọpụtara telmisartan dị ka ọfụma dị n’etiti mmadụ nwere ọbara mgbali elu.

Nsonaazụ

Dizziness, isi ọwụwa, syndrome na-adịghị ala ala, enweghi ike, ọgbụgbọ, afọ ọsịsa, na ọrịa akụkụ elu akụkụ okuku ume nwere ike ime mgbe ị na-ewere mycardis. Nsonaazụ ndịa bụ otu ihe. Patientsfọdụ ndị ọrịa na-emekwa mkpesa maka ụkwara.

Ihe banyere angioedema mere na ihe omumu a. Nke a na-egosi ahụmịhe gara aga na nsogbu abụọ a, ọ bụ ezie na ọ dịchaghị ala karịa nke ndị na - egbochi ACE, nwekwara ike ịdaba na ndị na - ekwenye ekwenye na AT1. Na nyocha anụmanụ, oke mbuze na ọnya afọ na-eme ugboro ugboro site na telmisartan.

Usoro onunu ogwu na nhazi

A na-ewere mbadamba okwu ọnụ, n'agbanyeghị nri.

Usoro izizi nke Mikardis na ọgwụgwọ ọbara mgbali: 1 mbadamba (40 mg) 1 oge kwa ụbọchị. A na-anabata mmụba nke okpukpu abụọ okpukpu abụọ n'ọnọdụ, mgbe ị na-ewere 40 mg kwa ụbọchị, enweghị ọgwụgwọ ọgwụgwọ ahụ ezubere. Ma mgbe ị na-ekpebi ịbawanye ọgwụ, ọ dị mkpa iburu n'uche eziokwu ahụ bụ na mmetụta antihypertensive kachasị na ọtụtụ ikpe nwere ike ịtụ anya naanị ụbọchị 28-56 mgbe mmalite ọgwụgwọ.

Usoro onunu ogwu iji welata oria obi na onwu bu 1 mbadamba (80 mg) 1 oge kwa ubochi. Na mmalite ọgwụgwọ, enwere ike ịchọ mgbazi ọbara mgbali elu ọzọ.

Dailybọchị Mikardis kwa ụbọchị maka ọrụ imeju na-arụ ọrụ nke ogo dị nwayọ na obere (klaasị A na B na ogo Child-Pugh) agaghị agafe 40 mg.

Achọzigharị usoro usoro usoro ọgwụgwọ maka ndị agadi agadi na ndị ọrịa nwere ọrịa gbasara akụrụngwa (gụnyere ndị nọ n'ọbara ha).

Ntụziaka pụrụ iche

N'ụfọdụ, n'ihi mkpochapu sistemụ renin-angiotensin-aldosterone, ọkachasị mgbe ị na-ejikọ ọgwụ ndị na-emetụta usoro a, ọrụ akụrụ na-emebi emebi (nke gụnyere nnukwu akwara renal). N'akụkụ a, ọgwụgwọ yana ụdị mgbochi abụọ nke usoro renin-angiotensin-aldosterone (dịka ọmụmaatụ, na mgbakwunye nke angiotensin-na-agbanwe enzyme inhibitors ma ọ bụ onye na-egbochi renin inhibitor, aliskiren, ka ndị mgbochi angiotensin II), kwesịrị ka ejiri ya rụọ ọrụ kpam kpam n'otu ụzọ ma jiri nlezianya nyochaa ya. akụrụ (gụnyere nlebara anya oge niile nke serum creatinine na potassium.

Mgbe ọrụ nke akụrụ na akwara olu na-adabere na ọrụ nke sistemụ renin-angiotensin-aldosterone (dịka ọmụmaatụ, na ndị ọrịa na-arịa ọrịa akụrụ ma ọ bụ obi na-adịghị ala ala, gụnyere ya na akwara akwara ma ọ bụ stenosis akụrụ), iji ọgwụ eme ihe na-emetụta na usoro a nwere ike isonyere na mmepe nke oliguria, hyperazotemia, nnukwu ọgbụgba ọbara na, n'ọnọdụ obere, nnukwu nsogbu gbasara akụrụ.

N'iburu n'uche ahụmịhe ị drugsụ ọgwụ ndị ọzọ na-emetụta sistemụ renin-angiotensin-aldosterone mgbe ị na-edepụta Mikardis na mgbakwunye nri, potassium-sparing diuretics, potassium nwere nri nnu na ọgwụ ndị ọzọ na-eme ka mkpokọta potassium dị n'ọbara (dịka ọmụmaatụ, heparin), A na-atụ aro ya ka ị chịkwaa ihe ngosi a na ndị ọrịa.

N'ihe banyere ọrịa mellitus nke ọrịa shuga na ihe ize ndụ ọzọ maka usoro obi, dịka ọmụmaatụ, na ndị ọrịa nwere ọrịa obi mellitus na ọrịa obi, ojiji nke ọgwụ ndị na-ebelata ọbara mgbali (dịka angiotensin na-agbanwe ndị na-egbochi enzyme ma ọ bụ ndị na-emegide angiotensin II) nwere ike ịbawanye n'ihe ize ndụ nke infarction myocardial infarction. na ọnwụ obi na mberede. Ọrịa obi na-arịa ọrịa shuga nwere ike ịbụ asymptomatic, na nke a, o yikarịrị ka ọnaghị achọpụta ya. N'akụkụ a, tupu ịmalite ọgwụgwọ Mikardis na ndị ọrịa nwere ọrịa mellitus, ọ na-atụ aro ka emee nchọpụta nyocha dị mkpa, gụnyere nnwale mmega ahụ, iji chọpụta ma gwọọ ọrịa obi.

Dịka usoro ọgwụgwọ ọzọ, enwere ike iji ọgwụ ahụ jikọta ya na thiazide diuretics (hydrochlorothiazide), nke gbakwunyere nwere mmetụta hypotensive (dịka ọmụmaatụ, Mikardis Plus).

Na isi aldosteronism, ọgwụ antihypertensive, onye usoro ya bụ iji gbochie usoro renin-angiotensin-aldosterone, dịka iwu, enweghị mmetụta achọrọ.

A na - ekekarị Telmisartan na bile. Site na ọrịa na-egbochi ọnya biliary ma ọ bụ ọdịda imeju, mbelata ọgwụ ịhapụ ọgwụ ahụ ga-ekwe omume.

Okwesiri iburu n'uche na Mikardis abaghị uru ọ bụla na ndị ọrịa agbụrụ Negroid.

Ọtụtụ ndị bi na Japan ka a hụrụ mmeju ọrụ imeju na-eme n'oge telmisartan.

Ndị ọrịa n'oge ọgwụgwọ kwesịrị ịkpachara anya mgbe ha na-eme ihe egwu nwere ike ịchọrọ nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Mkparịta ụka ọgwụ ọjọọ

Achọpụtaghị mmekọrịta dị n'etiti ọrịa na mgbakwunye, na mgbakwunye na ike nke telmisartan iji mee ka mmetụta hypotensive nke ndị ọrụ antihypertensive ọzọ mata.

Ojiji nke telmisartan na amlodipine, simvastatin, paracetamol, ibuprofen, glibenclamide, hydrochlorothiazide, warfarin ma ọ bụ digoxin anaghị eduga na mmekọrịta dị n'etiti ụlọ ọgwụ.

N'iji telsmisartan na digoxin, n'otu oge, a na-achọpụta mmụba nke nke abụọ na plasma ọbara site na nkezi 20% (n'otu oge, site na 39%). N'akụkụ a, a na-atụ aro ya mgbe ị na-ejikọta ụdị ọgwụ a iji chọpụta oge itinye digoxin n'ọbara.

Mgbe ị na-eji telmisartan na ramiprilat (ramipril), mmụba nke okpukpu abụọ na Cmax na AUC0-24 nke ndị nnọchi nke abụọ (egosighi mkpa ọhụụ nke ihe omume a).

N'ihe banyere ojiji nke angiotensin-n'ịtụgharị enzyme inhibitors na nkwadebe lithium, a hụrụ mmụba mbugharị nke mkpo lithium n'ọbara, nke a sokwa nsonaazụ nsị. N’oge na-adịbeghị anya, a kọrọ na mgbanwe ndị dị otú ahụ na ndị na-emegide ndị nnabata angiotensin II. A na-atụ aro ka ekpunye uche nke lithium n'ime ọbara n'otu oge iji ọgwụgwọ lithium na antagonensin II antagonist.

Ọgwụ na-abụghị ọgwụ steroidal anti-inflammatory ọgwụ, gụnyere cyclooxygenase-2 inhibitors, acetylsalicylic acid na ndị na-abụghị steroidal anti-inflammatory ọgwụ, nwere ike iduga mmepe nke nnukwu aha akwara ọdịda na ndị ọrịa nwere akpịrị nkụda mmụọ.

Ogwu ndi n’eme ihe banyere renin-angiotensin-aldosterone nwere ike inwe mmuta. N'ime ndị ọrịa na-a drugsụ ọgwụ mgbochi na - abụghị ọgwụ steroidal na telmisartan, na mmalite ọgwụgwọ, a na - atụ aro ka ọ kwụọ ụgwọ maka ịmegharị ọbara ma duzie ọmụmụ banyere akụrụ ọrụ.

A na-ebelata ịdị mma nke telmisartan n'ihi mgbochi nke vasodilating mmetụta nke prostaglandins mgbe ojiji nke Mikardis nwere ọgwụ mgbochi mkpali na-abụghị steroid.

Ọbara mgbali elu

N'ime ụwa nke oge a, nkụchi obi na ọnya na-akpata ihe fọrọ nke nta ka ọ bụrụ pasent 70 nke ndị nwụrụ anwụ. Taa, mmadụ asaa n'ime mmadụ iri ọ nwụrụ na-anwụ n'ihi akwara mkpụrụobi ma ọ bụ ụbụrụ nwere oghere. Nke kacha ewute bu eziokwu bu na otutu ndi mmadu anaghi enyo ihe obula ha na aru aru. Ọtụtụ ndị ọrịa n'ihi nke a na-efunahụ ohere idozi ihe, si otú ahụ na-ama onwe ha ikpe ọnwụ.

N'akụkụ a, mmadụ ekwesịghị ileghara ahụ ike mmadụ anya ma na-eleghara nyocha ahụike oge niile nke ndị dọkịta. Ma bụrụ na achọpụtara ọbara ọgbụgba, ọ dị mkpa ịme usoro niile maka ọgwụgwọ ya. Ngwá ọrụ kachasị dị irè maka ịgwọ ọrịa a taa bụ ọgwụ a na-akpọ "Mikardis".

Ihe omuma banyere ogwu

A na-ahụ ọgwụ a ọtụtụ ugboro dị irè karịa Losartan. Dịka ntuziaka ahụ si dị, Mikardis bụ ọgwụ na-egbu egbu. Ọ nwere ezigbo ọptionụ, a na-etinye ya kpamkpam na anụ ahụ, mana ọdịghị ọdịiche dị mgbe, ihe, na ole mmadụ riri. Ọgwụ ahụ, dịka iwu, amalite ị absorụ ya mgbe otu elekere na ọkara gasịrị. Maka nrụgide, ọ na-amalite ịda awa atọ mgbe ị takingụ ọgwụ ahụ. Nke a bụ ọrụ bụ isi Mikardis. Ọgwụ ahụ emeghị ọnọdụ maka nguzobe metabolites na-arụ ọrụ. Site na ahụ mmadụ, ọgwụ a kapịrị ọnụ na bile.

A gosipụtara ọgwụ a, gụnyere maka ndị ọrịa na-arịa ọrịa akụrụ. Dabere na ntuziaka maka ojiji, "Mikardis" enyeghị ndị mmadụ ọrịa imeju na-arịa ọrịa, yana mgbakwunye, maka ndị nwere nsogbu na ọnya biliary. Ndị ọrịa ahụ nwere ọdịda akụrụngwa na-agafeghị oke nwere ike iwe ihe karịrị 40 milligrams kwa ụbọchị.

Ofzọ nke itinye akwụkwọ na nsonaazụ nke ọgwụ

Dika ntuziaka a nyere Mikardis, na-achọ ị takingụ ọgwụ otu ugboro n'ụbọchị, n'agbanyeghị nri. Usoro ubochi nile bu milligrams 40. Site na ọbara mgbali elu mbụ, ọgwụgwọ na-amalite site na milligrams 20, n'ụdị siri ike, enwere ike ịbawanye ego ọgwụ ọgwụ gaa milligrams 160.

Ofdị irè nke ọgwụ a na-adabere na usoro onunu ogwu. Ọ bụrụ na ị na-abawanye usoro ubochi kwa ụbọchị site na 20 ruo 80 milligrams, nke a ga-apụta na nrụgide ga-agbada ugboro abụọ. Increbawanye onodu ogwu nke Mikardis ruo ihe karịrị 80 milligrams bụ ihe a na-achọghị, n'ihi na nke a agaghị enye aka na nrụgide dị ukwuu karị. Usoro mmezi nke ọgwụ ahụ bụ milligrams 40 kwa ụbọchị. Mgbe otu ọnwa gachara ọgwụ ahụ, nrụgide dị na mmadụ na-alaghachikarị ọtọ. Isi ihe bụ ilele onodu ogwu nke Mikardis.

N'ọnọdụ nke onye ọrịa ahụ nwere mmalite mmalite ọbara mgbali elu, ọ bụ ihe amamihe dị na ya iji zụta ọgwụ nke 40 milligram ma were ọkara mbadamba ụbọchị (ya bụ, 20 milligrams). Ọ bụrụ na mmadụ nwere ọdịdị na-adịghị ala ala, werezie 40 milligrams.

Ngwakọta nke "Mikardis"

Yabụ, ọgwụ a dị nso mejupụtara telmisartan, nke bụ mpaghara ihe na-arụ ọrụ. Na mgbakwunye, a na-etinye ihe ndị dị n'ụdị hydrochlorothiazide, polyvidone, sodium hydroxide, meglumine, magnesium stearate na sorbitol dị ka ndị inyeaka na Mikardis.

Kedu ihe na-egosi Mikardis?

Ihe ngosi maka ojiji

Ihe na-egosi maka iji ọgwụ mgbochi angiotensin na-atụ aro na onye ọrịa nwere nkụda obi na nephropathy, nke na-egosi dị ka nsogbu nke ọbara mgbali elu na ọrịa shuga. Dịka ntuziaka ahụ si dị, a na-a theụ ọgwụ ahụ iji mezuo ebumnuche ndị a:

• Ọgwụ ọbara mgbali elu.
• Mgbochi obi na ọrịa vaskụla.

Kedụ mgbe ọ dị mkpa ịutionụ ọgwụ?

N'ikwekọ na ntuziaka agbakwunyere maka iji mee ihe, ekwesịrị iji ọgwụ a "Mikardis" jiri nlezianya na n'okpuru nlekọta nke dọkịta na ndị ahụ na-arịa ọrịa ndị a:

• Ọrịa obi.
• Stenosis nke akwara gbasara akwara.
• Ọrịa obi na-adịghị ala ala.
• Stenosis nke valves obi.
• Ọrịa Cardiomyopathy ma ọ bụ ọbara ọgbụgba akwara.
• Hyperkalemia
• Ọkpụkpụ ọgbụgba na - ebugharị akụkụ ahụ.
• Mmebi nke mpụga bile.
• Ọrịa imeju.
• Ọrịa shuga mellitus.
• Akpịrị ịkpọ nkụ na nzụlite nsị nri. Ọ dị mma ịmara na n'ọnọdụ nke a, a ga-eweghachite ụfụ mmiri mmiri ozugbo iwere Mikardis. Ntụziaka ahụ kwadoro nke a.

Mikardis, ntuziaka maka ojiji: usoro na usoro onunu ogwu

Ekwesịrị iji okwu mbadamba Mikardis. Iri nri anaghị emetụta arụmọrụ nke ọgwụ.

Maka ọbara mgbali elu, a na-atụ aro ka ịmalite site na ntinye ọgwụ kwa ụbọchị nke 40 mg na 1 dose. Ọ bụrụ na ọgwụgwọ ahụ ezughi oke, a na-abawanye kwa ụbọchị ka ọ bụrụ 80 mg na 1 dose, ebe ekwesịrị iburu n'uche na mmetụta kachasị njọ nke Mikardis na-etolite n'ime izu 4-8 mgbe mmalite nke ọgwụgwọ.

Iji belata ihe egwu na ọrịa obi, ọ na-akwadoro ka ị were 80 mg otu ugboro kwa ụbọchị. Na nmalite ọgwụgwọ, enwere ike ịchọ mgbazi ọbara mgbali elu ọzọ.

Dailybọchị Mikardis kwa ụbọchị maka ndị ọrịa nwere ọrụ imeju na-arụ ọrụ nke ogo dị nwayọ ma na-agafeghị oke (klas A na B na ogo Child-Pugh) agaghị agafe 40 mg.

Ọgwụ nke na-agbatị ndụ

Mikardis bụ sartan, ma ọ bụ ihe nnabata angiotensin. A na-eji ọgwụ a agwọ ọrịa ọbara mgbali elu. Ofkpụrụ nke ọrụ nke sartans bụ na akụrụ na-emepụta renin mgbe ha mechara, nke na-agbanwe ụdị arụmọrụ nke angiotensinogen ka ọ bụrụ angiotensin-1, nke na-akachasị akwara ọbara ma bụrụ onye ọrịa.Gbaso n'ime ahụ na -eme ọtụtụ nzaghachi dị iche iche na-egbochi ọbara mgbali elu.

N'ihi ya, ọbara ọgbụgba ga-alaghachi na nkịtị ma ọ bụrụ na ọ buliri elu. Na nkenke n'ihi nke a, ndụ onye ọrịa na-arịa ọbara mgbali elu na obi, na mgbakwunye, ọrịa vaskụla, agbatịkwuru.

N'okpuru ebe a, anyị ga-atụle analogues nke Mikardis.

Analogs Ọgwụ

A na-emepụta mbadamba Mikardis na Austria, yabụ ọnụahịa Mikardis dị elu ma rute puku kwuru puku ruble n'otu ngwugwu, nke enwere ọgwụ ọgwụ iri abụọ na asatọ. Mana enwere ụdị analogues nke ọgwụ a, nke emepụtara na Russia, anyị na-ekwu maka "Angiakand", "Blocktran", "Aprovel", "Candesartan", "Atakanda", "Lozartan", "Cozaar", "Lozape", " Valse ”na“ Valsartan ”.

Drugsụ ọgwụ niile dị n’elu nwere otu ọgwụgwọ ọgwụgwọ dị ka Mikardis, mana ha dị iche na usoro onunu ogwu na ihe mejupụtara. Ihe analogues ndị a dị ọnụ ala, site na ihe dị ka otu narị na iri atọ ruble n'otu ngwugwu. N'etiti analogues na Mikardis si dị, ọ bara uru ịkọpụta ọgwụ ndị dị ka Telmista tinyere Teseo, Priitor, Twinsta, Telpres, Telsartan, Tsart na Hipotel.

Telmista bụ ọgwụ antihypertensive. Ọ dị n'ụdị mbadamba. Ihe dị n'ime ọgwụ ọgwụ telmisartan, nke nwere akụrụngwa antihypertensive, bụ antiotistin II receptor antagonist.

E gosipụtara ya maka ọbara mgbali elu, nnukwu ihe ike nke ọrịa na akwara nke afọ karịa afọ 55. Ọ contraindicated n'ụdị siri ike nke ọrịa dysfunction imeju, mgbochi biliary, jikọtara ya na aliskiren na ndị ọrịa nwere nnukwu ma ọ bụ na-agaghị ala ala akwara ma ọ bụ na-arịa ọrịa shuga, lactase / sucrose / isomaltase, fructose ndidi, glucose-galactose malabsorption, ịtụrụ ime na oge lactation, afọ ruo afọ 18, afọ ojuju nke telmisartan ma ọ bụ ihe ọ bụla inyeaka nke ọgwụ ahụ.

Ọnụ ego ọgwụ ndị German mere nwere otu ụdị ọgwụgwọ ahụ, yana ọgwụ nke ndị na-emepụta Hungarian na ndị Poland, dị ka iwu, dị ọtụtụ ugboro karịa ndị nnọchi Russia maka Mikardis. Mana ọ dị mma ịmara na taa enweghị ọgwụ Russia na ihe nwere ike.

Tụnyere ya na ọgwụ ndị ọzọ

Ọtụtụ ndị ọrịa na-echekarị ihe ka mma ime - "Lorista" ma ọ bụ "Mikardis"? Mkpụrụ ọgwụ abụọ a na -ebelata nrụgide n'ụzọ dị irè, mana ihe ndị na-arụ ọrụ n'ime ha dị iche kpamkpam. Costgwọ a dịkwa iche. Dịka ọmụmaatụ, ọgwụ "Lorista" na-akwụ ihe dị ka narị atọ ruble, ebe "Mikardis" na-akwụ ndị ahịa ụgwọ ugboro atọ karịa.

Tụnyere "Mikardis" na "Valz", ọ bara uru ịmara na ọgwụ ikpeazụ ahụ dịkwa ọnụ ala karịa. "Valz" na-akwụ ihe dị ka narị ruble atọ. Ma ha na-eji ya dị ka akụkụ nke ọgwụgwọ nke ọrịa obi na-adịghị ala ala. A nwekwara ike iji ya gwọọ ndị ọrịa merụrụ ahụ ma ọ bụ nkụchi obi.

Ọtụtụ mgbe ndị mmadụ na-anwa ịtụle Mikardis na Lisinopril. Ekwesịrị m ikwu na ọgwụ ndị a dị iche iche nke ọgwụ ọjọọ. Ọgwụ ndị a nwere ihe dị iche iche dị iche iche na - arụ ọrụ, na mgbakwunye, usoro nke mmetụta ha na ahụ mmadụ dịkwa iche. "Lisinopril" na-arụ ọrụ dị ka ihe mgbochi ACE na mgbakwunye na-akpata ọnụ ọgụgụ dị ukwuu nke mmeghachi omume ọjọọ. A na-emepụta mkpụrụ okwu a na Russia, ọnụ ahịa ya dịkwa ihe dị ka otu narị na iri abụọ rubles.

Shouldkwesịrị ịtụle Mikardis na Concor. Ọgwụ ndị a gosipụtara nwekwara usoro dị iche iche eji arụ ọrụ. "Nchebe" dị irè ọ bụghị naanị ma ọ bụrụ na onye ọrịa nwere ọbara mgbali elu, kamakwa megide ndabere nke ischemia na nkụda obi.Abụọ ọgwụ ndị a na-anabata ndị ọrịa nke ọma, dabere na usoro onunu ogwu. Consor nwere mmepụta German, ọnụ ahịa ya dịkwa narị atọ na iri ise rubles.

Ọ dị mkpa iburu n'uche na mgbe ịkwụsị ọrụ ọgwụgwọ na Mikardis, ndị ọrịa anaghị ahụ akara mgbapụta, yana usoro olu, jiri nwayọ laghachi ụkpụrụ ha mbụ. Okwesiri ime ka ọ pụta ìhè na Mikardis na-arụ ọrụ dị ka ọgwụ antihypertensive dị irè nke ndị ọrịa na-anabata nke ọma. Na mgbakwunye, ọgwụ a nwere ọnụ ọgụgụ dị nta nke contraindications.

Mana ọgwụ a gosipụtara nwere ọnụ ahịa dị elu, yabụ, na ọgwụgwọ ogologo oge, ọtụtụ ndị ọrịa na-anwa ịchọta analogues dị ọnụ ala. N'akụkụ a, ọ dị mkpa icheta na ọ bụ naanị dọkịta nwere ike dochie ọgwụ, nke bụ eziokwu bụ na ọbụna mkpụrụ ndụ ihe nketa anaghị enwe mmetụta ọgwụgwọ ahụ mgbe niile.

Nsonaazụ nke Mikardis

Ogwu a, dika egosiputara n’ime ntuziaka ojiji eji ogwu a, enwere otutu nsogbu o bula na-eme ugboro ugboro, mana n’agbanyeghi ike ihu. Anyị na-ekwu maka afọ ọsịsa, myalgia, dizziness, ịda mba, ịba ụba ụjọ, ọdịdị nke ihe mgbu na sternum na ụkwara na-enweghị mkpụrụ. Na mgbakwunye, ihe ịre nke akpụkpọ ahụ mucous nwere ike yana yana anaemia, urticaria na pruritus.

Kedu ihe jikọrọ Mikardis na mmanya?

Enwere m ike ijikọ ya na mmanya?

N'oge ọgwụgwọ, ị alcoholụ mmanya na-aba n'anya, na mgbakwunye, ị ,ụ ọgwụ ọ bụla nke gụnyere ethanol, amachibidoro. Site na njikọ a, mmetụta ndị na-emetụta akụkụ na ọnọdụ dị oke njọ nwere ike ime.

Tụlee nyocha nke Mikardis.

Nyocha nke ndị ọkà mmụta gbasara akụrụngwa gbasara ọgwụ

Nyocha nke ndị ọkà mmụta gbasara akwara banyere ọgwụ a na-akacha mma. Dika ndi dibia siri kwuo, oburu na imebighi usoro ogwu gi ma tupu ijiri ule di nkpa maka nnabata oria a bu nke contraindications na iji Mikardis, ihe ahu gha agha aghaghi idi.

Ndị ọkachamara na-ede na usoro ọgwụgwọ a n'ọtụtụ ọnọdụ na-ewere ọnọdụ na enweghị mmerụ ahụ dị egwu ọ bụla. Na nkwupụta ọgwụ, a na-ekwusi ike na ọbụlagodi na mmeghachi omume ọjọọ pụtara, ha na-aga n'ihu n'ụzọ adịghị ike. Cardiologists chọpụtara na obere mmetụta ọgwụ a na rhythm obi. Tinyere ihe ndị ọzọ, ndị ọkachamara na-ahụ ike dị elu nke ọgwụ enyere, ọbụlagodi mmalite nke ọbara mgbali ala ala.

Ọzọkwa, ndị dọkịta na nyocha nke "Mikardis" na-akọ na, ọ bụrụhaala na a hụrụ usoro ziri ezi maka ịillsụ ọgwụ ndị a, ọgwụ ahụ na-ebute nsonaazụ n'ahụ ahụ onye ọrịa, nke na-ewe awa iri anọ na asatọ.

Nyocha nyocha Ndidi

Banyere ọgwụ "Mikardis" nyocha nke ndị ọrịa dịkwa mma. Naanị ihe ndọghachi azụ nke ọgwụ German a, dịka ndị mmadụ si kwuo, ọ bụ ego dị oke ọnụ. Ọnụahịa ọgwụ ahụ, dị ka anyị kwuru na mbụ, bụ otu puku rubles. N'ezie, ọnụahịa dị otú ahụ agaghị adabara onye ọ bụla. Karịsịa, ndị na-akwụ ụgwọ ezumike nká bụ́ ndị na-emefu nnukwu ego na ọgwụgwọ ha kwa ọnwa na-eme mkpesa banyere ọnọdụ a.

N'etiti nyocha dị mma banyere ọgwụ a, e nwere nkwupụta na ọgwụgwọ "Mikardis" na-eso ndị ọbịa nke ọma. Yabụ, ọ ga-ezu ị toụ naanị otu mbadamba otu ugboro n’ụbọchị, ka ụbọchị ndị ọzọ wee dị gị mma ma jiri ike nkịtị gawa ije. Ndị ọrịa, dị ka ndị dọkịta, na-akwado na mmetụta ọ bụla dị njọ ọ bụla metụtara ojiji nke ọgwụ a dị ụkọ.

Tinyere ihe ndị ọzọ, ndị mmadụ na-akọ na ekele maka Mikardis ha jisiri ike wepụ nkụchi na nrụgide mberede na nrụgide.Achọpụtala na ọnwa gara aga mgbe ị na -enweta nri kwa ụbọchị, nrụgide ahụ na-akwụsị ima elu ma bụrụ ihe nkịtị. Ndị na-azụ ahịa na-etokwa ọgwụ a maka inye aka belata ọbara mgbali na-enweghị mmerụ ọ bụla obi.

Patientsfọdụ ndị ọrịa na nyocha ha na-akọ na ha theụrụ ọgwụ "Mikardis" na njikọta na ọgwụ ndị ọzọ iji belata ọbara mgbali. Karịsịa, ndị ọrịa na-arịa ụdị ọbara mgbali elu na-agbaso usoro ọgwụgwọ dị otú ahụ. Ndị na-azụ ahịa na-ede na na nke a, Mikardis na-anagide ọrụ ya nke ọma, mana mgbe ụfọdụ akpụkpọ ahụ na-asọ ya n'ọbụ aka.

Etu ị ga - esi mee ya, oleekwa ụdị usoro onunu ogwu a

Naanị ihe ngosipụta gọọmentị maka telmisartan bụ ọbara mgbali elu. Ekwesighi iwere Telmisartan maka nkụchi obi.

Mikardis dị na mbadamba 40 na 80 mg. Mpempe akwụkwọ agaghị agbaji n'ihi ihe ndị dị na physicochemical ha. A na-a drugụ ọgwụ ahụ otu ugboro n'ụbọchị. Ọgwụ mbụ bụ 40 mg / ụbọchị. A na-atụ anya oke mmetụta n’ime izu anọ. Ọ bụrụ na ọ dị mkpa, enwere ike ịgbatị okpukpu abụọ ruo 80 mg / ụbọchị. Telmisartan na thiazide diuretic na-aga nke ọma. Ekwesịrị iji Mikardis jiri nlezianya mee ihe mgbe akpịrị kpọrọ nkụ, ma ọ bụghị na nnukwu akụrụ. N'ihe banyere nsị imeju, a na-atụ aro ka ị belata ọnya.

Dị ka ihe angagonensin receptor antagonists, telmisartan na contraindicated na ime (na akụrụ odida na nwa ebu n'afọ). Onweghi ahuhu imu ara.

Aha ahia ndi isi:

Dị Mkpa! A na-enye ọgwụ a ka ọfụma dịka ndenye ọgwụ ndị na-ahụ maka ịga. A naghị atụ aro ka ịzụta ọgwụ ahụ n'enweghị ndenye ọgwụ.

Mmekorita

Telmisartan nwere ike ibute mmụba nke digoxin n'ime ọbara, ọ bụ ezie na aghọtaghị usoro nke usoro a. Ya mere, ekwesịrị inyocha ọkwa digoxin mgbe ọgwụgwọ ọrịa telmisartan malitere ma ọ bụ kwụsị. Na mgbakwunye, a na-atụgharị uche na angiotensin II antagonist antagonists nwere ike iwelie ọkwa lithium. Anaghi akwado ya ka iwere telmisartan na nkpuru nkpuru osisi.

Ihe ọ juiceụụ mkpụrụ osisi grape

Mmanya na-egbochi mkpụrụ ndụ akwara na-egbochi nnukwu ọgwụ ma nwee ike ịkwalite mmetụta vasodilating nke ọgwụ ahụ. A naghị atụ aro ị alcoholụ mmanya n'oge ị na-eji ọgwụ ahụ. Na obere doses, ethanol nwere mmetụta na-enweghị atụ na pharmacodynamics na ọgwụ ọgwụ, mana na nnukwu doses ọ nwere ike ibute nsị.

Ndụmọdụ! Tupu ị theụ ọgwụ ahụ, ịkwesịrị ịgakwuru dọkịta. Amachibidoro ya ịzụrụ na iji ọgwụ ahụ n'enweghị ọgwụ ọ bụla dọkịta depụtara. Iji akpachapụghị anya nwere ike ịkpata nsonaazụ ya.

Ihe ngosi maka ojiji

Ọzọkwa, a na-eji ọgwụ ahụ eme ihe iji belata ọrịa obi na, yabụ, ọnụ ọgụgụ ndị mmadụ karịrị afọ iri ise na ise nwere nnukwu nsogbu ibute ọrịa obi.

Usoro onunu ogwu na uzo ochichi

Ntụziaka eji eme ihe na-egosi na edere Mikardis n'ime, n'agbanyeghị nri nri.

1. Iji belata ọrịa obi na akwara, ọgwụ a tụrụ aro bụ 1 tab. (80 mg) 1 oge / ụbọchị. N’oge mmalite ọgwụgwọ, enwere ike ịchọ mgbazi ọbara mgbali elu ọzọ.
2. Site n'ọbara mgbali elu, usoro ọgwụgwọ akwadoro nke Mikardis bụ taabụ 1. (40 mg) 1 oge / ụbọchị. N'ọnọdụ ebe enweghi ike nweta ọgwụgwọ ọgwụgwọ, enwere ike ịba ụba nke ọgwụ ahụ ka ọ bụrụ 80 mg 1 oge / ụbọchị. Mgbe ị na-ekpebi ma ịbawanye ọgwụ ahụ, ekwesịrị iburu n'uche na mmetụta antihypertensive kachasị na-arụkarị n'ime izu 4-8 mgbe mmalite nke ọgwụgwọ.

Ọria achọrọ ndị ọrịa nwere akụrụngwa akụrụngwa (ya na ndị nke metụtara ịwa ahụ).

N'ime ndị ọrịa nwere ọrụ imeju na-arụ ọrụ nke obere ruo ogo dị ala (klas A na B n'ọtụtụ -mụaka), kwa ụbọchị ọgwụ ahụ agaghị agafe 40 mg.

Usoro usoro onunu ogwu n’ebe ndi agadi no achoghi mgbanwe.

Ọnọdụ nchekwa na ndụ nchekwa

Na-echekwa n'ebe ọkpọkọ na-erughi ụmụaka aka na ọnọdụ okpomọkụ na-erughi + 30 Celsius С.

Mikardis bụ ọgwụ gbasara ọrịa obi.
Ọ mejupụtara ihe ndị a dị ka telmisartan, sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.
Ihe mejupụtara ọgwụ ahụ na-eme ka mgbasawanye nke akwara ọbara, nke na-ebelata ọbara mgbali. Ọgwụ dị oke irè, ihe ọ na - eme bụ mgbe awa ole na ole gasịrị.

Registered debara aha ọgwụ ahụ?: lelee ☜

Medicine gbakwunyere: 2010-03-11.
Ntụziaka emelitere: 2017-08-25

Ntụziaka dị mkpirikpi maka iji, contraindications, ihe mejupụtara

Ihe ngosiputa (gini na - enyere aka?)
Ejiri ya n'ọtụtụ ebe iji na-agwọ ọbara mgbali elu. A na-ejikarị ya eme ihe mgbochi, maka ndị agadi, iji belata ọrịa nke usoro obi.

Ihe ngbanwe
Amachibidoro ya iwu iji mycardis mgbe:
1. onye ọrịa nwere ọrịa imeju,
2. pụrụ iche nghọta site na ahu nke fructose na lactose,
3. mgbochi afọ (ndị na-eto eto na-erubeghị afọ iri na asatọ),
4. n’oge ime na n’ara,
5. enwere ọrịa nke biliary tract.
N’inye nlezianya pụrụ iche, a na-enye ndị ọrịa iwu maka ọrịa akụrụ, maka hyponatremia, maka hyperkalemia, maka akụrụ mgbe oge ntụgharị, maka nnukwu nkụchi obi, maka ụdị stenosis dị iche iche.

Ofzọ nke ngwa (usoro onunu ogwu)
Mbadamba nkume a na-ede ede, n'agbanyeghị nri a ga-eri. Usoro ogwu a ka atọrọla onwe ya maka onye ọrịa ọ bụla, oge a na-agwọ ya dị ogologo. Na ọgwụgwọ nke dose bụ otu ọgwụ otu ugboro n’ụbọchị, ọ bụrụ na ọ dị mkpa, enwere ike okpukpu abụọ.

Ingsdọ aka na ntị
A machibidoro iji mycardis na aliskeren (maka ọrịa shuga). Ọ baghị uru ijikọ ya na ọgwụ nwere lithium.

Nsonaazụ
Mikardis kpatara otutu ihe ndi ozo:
1. ọrịa akụkụ okuku ume na elu,
2. Cystitis
3. anaemia,
4. nsogbu ehighị ụra, ịda mba n’obi, nchekasị,
5. enweghi ike ịhụ ụzọ,
6. mbelata nke ọbara mgbali elu,
7. bradycardia, tachycardia,
8. ike ọgwụgwụ, mkpụmkpụ ume,
9. afọ mgbu, flatu, afọ ọsịsa.
10. akọrọ ọnụ, ọgbụgbọ, ọgbụgbọ,
11. Mmeghachi omume nfụkasị (ọnya, urticaria, itching),
12. Ahụ mgbu, akpụ ụkwụ,
13. arụrụ ọrụ na-arụ ọrụ gbasara arụrụ, ruo n'ịrụ oke akwara,
14. mgbu na mpaghara obi na adịghị ike nke anụ ahụ.

Dodoụbiga ya ókè
Onweghi okwu ịdoụ ọgwụ ọdoụ .ụ riri nne.

Mpempe mwepụta
A na-emepụta ya n'ụdị mbadamba, ọcha, oblong, na ngwugwu ọnya nke 7 nkeji.

Aro / nyocha nke ndi dibia: anyị nwere ngalaba dị ukwuu maka ịgagharị na weebụsaịtị anyị, ebe a na-atụle Mikardis ọgwụ ahụ otu oge site na ndị ọrịa na ndị dọkịta - lee

Mikardis - ọgwụ maka igbochi ọrịa obi

"Mikardis" bụ ọgwụ mepụtara na ntọala nke ihe pụrụ iche arụ ọrụ /

Ọ bụ ụzọ dị irè e si emegide ndị na-anabata angiotensin.

Ngwongwo ọgwụ a na-enye gị ohere iji nwayọ emetụta ahụ mmadụ ma nye nsonaazụ kachasị na ọgwụgwọ nke ọrịa.

1. Ntụziaka maka ojiji

Taa, a na - eji "Mikardis" mee ihe n'ọtụtụ ọgwụ. Ọ bụ ndị dọkịta depụtara ọgwụ ndị a iji gwọọ ọrịa dị iche iche.

Dịka ntuziaka ahụ si dị, enwere ike ị drugụ ọgwụ ahụ n'ọnọdụ ndị a:

Mkpa ọgwụgwọ maka ndị ọrịa na-ata ahụhụ site na ngosipụta nke ọbara mgbali elu dị mkpa.

1. Maka ọgwụgwọ nke ọrịa dị iche iche nke usoro akwara obi (maka ndị nwere ọrịa shuga, yana ndị metụtara ọgwụgwọ ọnya afọ ma ọ bụ ọrịa obi).
2. Iji gbochie ihe egwu nke ọdịdị nke otu ọrịa obi.

2. Usoro ọgwụgwọ na nhazi

Ekwesịrị iji mbadamba Mikardis naanị ọnụ, ebe ha na-a drinkingụ nnukwu mmiri ọ drinkingụ drinkingụ nkịtị. The Tụ ọgwụ anaghị adabere n’oge iri nri.

Site n'ọbara mgbali elu, a na-adụ ndị ọrịa ọdụ ka ha họrọ usoro izizi ọgwụ a, nke agaghị agafe 40 mg kwa ụbọchị. N'ọnọdụ ụfọdụ, iji ụdị ọgwụ a, ọ gaghị ekwe omume iji nweta ọgwụgwọ ọgwụgwọ a chọrọ, ya mere, ọ dị mkpa ka iwelie ọgwụ ahụ gaa na 80 mg otu ugboro n'ụbọchị.

Ọ dị mkpa iburu n'uche eziokwu ahụ bụ na ọgwụ ọgwụ ike kachasi ike na-apụta naanị ọnwa 1-2 ka mmalite ọgwụgwọ.

Iji belata ohere nke ọrịa obi, dịka iwu, ndị ọrịa na-ewere mbadamba 80 mg kwa ụbọchị n’otu ọgwụ. Maka ụfọdụ ndị, na mmalite nke usoro, ịgbazi ọbara ọgbụgba nwere ike ịdị mkpa.

Ndị mmadụ na-arịa arụ ọrụ akụrụ nwere nsogbu ịhọrọ ọ bụla.

Maka ndị ọrịa nwere ọrịa imeju na-arụ ọrụ nke ọma, usoro a na-atụ aro kwa ụbọchị anaghị agafe 40 mg otu ugboro n'ụbọchị.

Kwa afọ na Russia, a na-eme ndekọ banyere nchọpụta ahụ - angina pectoris. Muta ihe banyere oria na ọgwụgwọ oria a:

1. Zọ ọgwụgwọ ọgbara ọhụrụ.
2. Ihe nrịba ama nke angina pectoris.

A na-eme Mikardis n'ụdị oblong, obere mbadamba ihe na-acha ọcha ma ọ bụ na-acha ọcha.

Ejiri ihe ndị a dị ka ọgwụ nke ọgwụ a:

1. Telmisartan bụ ihe na-arụ ọrụ.
2. Ndị pụrụ iche: magnesium stearate, povidone, sorbitol, sodium hydroxide, meglumine.

Mmetụta ikike ịkwọ ụgbọala na usoro dị mgbagwoju anya

Ọmụmụ ihe nyocha ahụike pụrụ iche na nsonaazụ Mikardis n'ikike itinye uche na ọsọ nke mmeghari emebeghị. Agbanyeghị, enwere ike ịnweta nsonaazụ ndị ọzọ dị ka ụra ụra na anya mmiri, ọ na-atụ aro ịkpachara anya mgbe ị na-anya ụgbọala na-arụ ọrụ nwere ike ịdị ize ndụ.

Ime na lactation

Emebeghi ihe omumu nke telmisartan banyere omumu mmadu.

N'ime oge izizi nke ịtụrụ ime, a machibidoro ndị nnabata angiotensin II ihe mgbochi. N'ihe banyere ịchọpụta ịtụrụ ime n'oge ọgwụgwọ, ekwesịrị ịkagbu Mikardis ozugbo na, ọ bụrụ na ọ dị mkpa, ekwesịrị ịdebe usoro ọgwụgwọ ọzọ (ọgwụ ndị na - egbochi ọgwụ nke ndị ọzọ kwere ka ha jiri ya n'oge oge ọmụmụ).

N'ime oge nke II na III nke afọ ime, akwadoghị iji Mikardis. Ọ bụ ezie na achọpụtaghị nsonaazụ teratogenic na ọmụmụ ọmụmụ, a malitere inwe fetotoxicity (ọrụ nwatakịrị nwere nwayọ, mkpụmkpụ nke isi, oligohydramnion) na nsonye obi na-egbu egbu (mgbagha ọgbụgba, hyperkalemia, ọdịda akụrụ).

N'ihi ya, a machibidoro Mikardis ahụ oge ime. Ọ bụrụ n’ozi ụfọdụ ejiri ọgwụ mee ihe n’afọ nke atọ, a na-atụ aro ka inyocha ọkpụkpụ na akụrụ nke nwa ebu n’afọ. O kwesịrị ileba anya ụmụ amụrụ ọhụrụ nke nne mụrụ telmisartan maka mmepe nke hypotension arterial.

Shouldmụ nwanyị ndị na-eme atụmatụ ịtụrụ ime kwesịrị ka e nye ha ọgwụgwọ ọzọ.

N'oge a na-enye nwa ara, a machibidoro iji Mikardis iwu.

Bụrụ na nke arụ ọrụ ezumike ọrụ

Ndị ọrịa nwere ọdịda akụrụngwa, gụnyere ndị nọ n'ọrịa hemodialysis, anaghị achọ ndozigharị nke Mikardis.

Iji nlezianya kpachara anya, a ga-eji Mikardis mee ihe ndị a: arụ ọrụ na-arụ ọrụ na-arụ ọrụ akwara, akwara ma ọ bụ akwara akwara akwara, yana ọnọdụ mgbe akụrụ akụrụ.

Na arụ ọrụ imeju

Mikardis nwere contraindicated na ikpe nke nnukwu ịba ọcha n'anya (klas C na Child-Pugh ọnụ ọgụgụ) na isi isi ihe na-anọghị n'ihe ọmụmụ.

N'ọrịa ịba ọcha n'anya dị nro na obere (andmụaka na Pugh na A na B), ọgwụ kachasị ekwenye ekwenti na-anọ kwa ụbọchị bụ 40 mg.

Ojiji nke Mikardis ọgwụ

Ndị okenye Ntinye ọgwụ a tụrụ aro maka ndị okenye kwa ụbọchị bụ 40 mg. N'ime ụfọdụ ndị ọrịa, ọgwụ nke 20 mg / ụbọchị nwere ike ịdị irè. Site na arụmọrụ na-ezughi oke, enwere ike ịba ụba nke ọgwụ a ruo 80 mg otu ugboro n'ụbọchị ma ọ bụ jikọtara ya na thiazide diuretics (hydrochlorothiazide), nke na-enye nsonaazụ hypotensive karị ma e jiri ya tụnyere monotherapy. Mgbe ị na-abawanye dose ahụ, ekwesịrị iburu n'uche na oke antihypertensive mmetụta na-etolite mgbe izu anọ 4-8 site na mmalite ọgwụgwọ.
Enwere ike ịgwọ ndị ọrịa nwere ọbara mgbali elu (mgbali elu akwara) na Telmisartan monotherapy na dose nke 160 mg / ụbọchị ma ọ bụ na njikọta na hydrochlorothiazide na dose nke 12.5-25 mg / ụbọchị, nchikota a dị irè.
A na-ewere ọgwụ ahụ n'agbanyeghị nri.
A na-ekpebi oge ọgwụgwọ ga-ekpebi n’otu n’otu, ọ dabere n’ụdị ọrịa ahụ na arụmọrụ nke usoro ọgwụgwọ ahụ.
Ndị ọrịa nwere ọrụ mgbazinye nsogbu. Patientschọgharị ndị ọrịa na nsogbu ọdịda akụrụngwa achọghị mmezi dose. A naghị ewepụ Telmisartan n'ọbara n'oge ọbara ọgbụgba.
Ndị ọrịa nwere ọria imeju. N'ime ndị ọrịa nwere ọrụ imeju dị nro ma ọ bụ nke na-adịghị ala ala, ọgwụ kwa ụbọchị ekwesịghị ịkarị 40 mg.
O ghaghi imeghari udiri ogwu n’egwu ndi okenye.
Enweghị data na nchekwa na arụmọrụ nke Mikardis mgbe ejiri ya na ụmụaka na ndị nọ n'afọ iri na asatọ.

Nsonaazụ nke ọgwụ Mikardis

Ọnọdụ ndị na-akpata mmetụta mgbe ọ na-ewere telmisartan (41.4%) na-abụkarị nke a na-ewere ya na iwere placebo (43.9%) n'ọmụmụ ihe na-achịkwa placebo. Ọrịa nsonaazụ anaghị esite na ntụtụ na okike, afọ ma ọ bụ agbụrụ ndị ọrịa. Achọpụtara mmeghachi omume ọjọọ ndị dị n'okpuru ebe a na ule nyocha nke metụtara ndị ọrịa 5788 na-ewere telmisartan.
Ọrịa na ozi: ọrịa urinary tract (gụnyere cystitis), ọrịa akụkụ iku ume nke elu.
Ọrịa uche: nchebara echiche
Site n'akụkụ akụkụ ahụ nke ọhụụ: imebi ebe obibi (ọhụụ siri ike).
Ọrịa Vestibular: anya ntughari.
Gastrointestinal: mgbu afọ, afọ ọsịsa, akpọnwụ akpọnwụ, dyspepsia, flatulence, ọrụ afọ.
Site na anụ ahụ ma ọ bụ anụ ahụ dị n'okpuru: eczema, ọsụsọ na-agba.
Site na usoro akwara na mọzụlụ: ọrịa ogbu na nkwonkwo, azụ mgbu, ihe mgbu akwara nke nwa ehi ma ọ bụ mgbu ụkwụ, myalgia, mgbaàmà ndị yiri akwara.
Ihe ndị a na-emekarị: obi mgbu, mgbaàmà ndị dị ka ọrịa.
Na mgbakwunye, okwu banyere erythema, pruritus, syncope / ọnwụ nke nsụhọ, nsogbu ehighị ụra, ịda mba, ọgbụgbọ, hypotension (gụnyere hyperension orthostatic hypotension), bradycardia, tachycardia, imeju akwara, ọrụ akụrụ, gụnyere nnukwu akụrụ gbasara akwara (lee ụdị FEATURES, ka a kọrọ). AKPỌRỌ), hyperkalemia, mkpirisi iku ume, anaemia, eosinophilia, thrombocytopenia, adịghị ike na enweghị arụmọrụ. Amaghị ugboro ole ụdị mmetụta ndị a amataghị.
Dị ka ọ dị ndị ọzọ na-emegide mmụọ angiotensin II, a kọọrọ ndị ikpe dịpụrụ adịpụ maka angioedema, urticaria, na mmeghachi omume ndị ọzọ yiri ya.
Nnyocha ụlọ nyocha: ọ dịkarịrị na mbelata nke hemoglobin ma ọ bụ mmụba nke ọkwa uric acid, a kọkwara banyere mmụba nke enzyme na creatinine ma ọ bụ imeju, mana oge ha jikọtara ọnụ ma ọ bụ obere ma e jiri ya tụnyere placebo.
Na mgbakwunye, okwu banyere mmụba nke ọkwa CPK na-akọ site na nyocha ndebanye aha.

Mkparịta ụka ọgwụ ọjọọ Mikardis

Telmisartan nwere ike ime ka ndị hypotensive ndị ọrụ antihypertensive ndị ọzọ nwee ike.
Agwakọta ihe omumu banyere nyocha nke pharmacokinetics: digoxin, warfarin, hydrochlorothiazide, glibenclamide, ibuprofen, paracetamol, simvastatin na amlodipine.
Maka digoxin naanị, a ga-atụba 20% (n'ọnọdụ ụfọdụ 39%) na ntinye uche ya na plasma ọbara n'ihe dị ka ọkwa dị, ya mere, ekwesịrị ịbanye na ọkwa nke digoxin na plasma ọbara.
Site na iji nnu nke lithium mee ihe n'otu oge, ọ ga - ekwe omume ịbawanye mkpo lithium na plasma ọbara na mmepe nke mmeghachi omume nsi, ya mere ọ dị mkpa ileba anya na ọkwa nke lithium na plasma ọbara.
Usoro ọgwụgwọ NSAID (gụnyere acetylsalicylic acid na doses karịrị 0.3 g kwa ụbọchị, na ndị na-egbochi COX-2) nwere ike iduga mmepe nke nnukwu akụrụ nke ọdịda na ndị ọrịa akpịrị. Ngwakọta na-emetụta sistemụ renin-angiotensin, dịka ọmụmaatụ telmisartan, nwere mmetụta mmekọrịta. Na mbido nchikota ọgwụ nke NSAIDs na Mikardis, ndị ọrịa kwesiri ịchọpụta hydration zuru oke ma lelee ọrụ ezumike. Site na usoro ọgwụgwọ oge a na NSAIDs, mbelata mmetụta nke ọgwụ ọgwụ antihypertensive, dị ka telmisartan, ka akọpụtara n'ihi mmachi nke vasodilator mmetụta nke prostaglandins.

6. Usoro na ọnọdụ nchekwa

Ekwesịrị ịchekwa Mikardis n'ebe ọkpọka nwere ikuku ikuku dị ala, nke a na-enyocha ya mgbe niile ma bụrụ onye a pụrụ ịdabere na ya site na ìhè anyanwụ. Ọgwụ ekwesịghị ịdị ụmụaka aka.

Ndụ shelf ọgwụ a bụ afọ abụọ.

Na ụlọ ahịa ọgwụ dị n'ókèala nke Russian Federationmbadamba nkume na-eri site na 300 rubles kwa ngwugwu.

Na ụlọ ọgwụ ndị Ukraine ọnụahịa ha sitere n'ihe dị ka hryvnia 115.

Ihe atụkarịkarị ọgwụ a gụnyere ndị a:

Nyocha banyere ọgwụ Mikardes na-adịkarị mma, ndị ọrịa na-achọpụta nsonaazụ dị mma nke mmetụta ọgwụ ahụ nwere n'ahụ ahụ, dịka ọmụmaatụ Alina dere, sị: “Ọgwụ dị mma. Ọ bụ site na enyemaka ya ka m wepụrụ ọbara mgbali dị mkpa. Ahụghị m mmetụta ọ bụla. M na-akwado ya maka onye ọ bụla na-enweghị ihe mgbochi ahụ. ”

Alena: “Nkwadebe dị nro. Dọkịta ahụ tiri iwu maka mgbochi ọrịa obi. Enwere m mmasị na nsonaazụ ahụ. ”

Nwere ike ịmatakwu banyere nyocha ndị ọrụ ndị ọzọ, kọọkwara echiche gị na njedebe nke edemede.

Edere ọgwụ Mikardes maka ịgwọ ọtụtụ ọrịa obi. Edeghị ọgwụ ahụ n’oge ịtụrụ ime, mmebi iwu nke imeju na akụrụ, n’oge ime. Iji zere mmetụta ndị ọ ga-ekwe omume na ịdoụbiga mmanya ókè, a ghaghị ị takenụ ọgwụ ahụ na nkwenye dọkịta.

Otu mbadamba Micardis nwere 40 mg ma ọ bụ 80 mg telmisartan (ike ihe).

Ndị e mere: sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.

Mikardis Ahịa

Na Russia, ngwugwu nke 80 mg Nke 28 ga-efu site na 830 ruo 980 rubles. Na Ukraine, ọnụahịa Mikardis n'otu mbipụta ahụ na-eru nso hryvnias 411.

• Pharlọ ọgwụ n'ịntanetị dị na Russia
• Aclọ ahịa ọgwụ n'ịntanetị na UkraineUkraine
• Pharmlọ ahịa ọgwụ dị n'ịntanetị na Kazakhstan

• Mikardis Plus mbadamba 80 mg + 12.5 mg 28 pcs Boehringer Ingelheim Böhringer Ingelheim
• Mbadamba Mikardis 80 mg 28 PC.
• Mbadamba Mikardis 40 mg 28 pcs Boehringer Ingelheim Böhringer Ingelheim

• Mikardis 40mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis gbakwunyere 80mg / 12.5mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis 40mg Nke 14 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis 80mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG

Pharlọ ọgwụ Pani

• Mikardis tab. 80mg Nke 28Beringer Ingelheim
• Mikardis tab. 80mg Nke 28Beringer Ingelheim

• Mikardis® Plus 80 mg / 12.5 mg Nke 28 mbadamba Boehringer Ingelheim Pharma KG (Germany)
• Mikardis® 80 mg Nke 28 mbadamba Boehringer Ingelheim Pharma KG (Germany)

Kwụsị uche! Ihe omuma banyere ogwu nke saịtị a bu ihe banyere nbuso-agha, anakpo ya site n public isi obodo ma na enweghi ike ibu ihe ndabere iji kpebie etu ogwu si di. Tupu ị Mikụ ọgwụ Mikardis, jide n'aka ịkpọ dọkịta gị.

Ọgwụ "Mikardis": analogues, ntuziaka maka ojiji, nyocha:

Edere Mikardis nye ndị ọrịa ka ha wepu ihe ịrịba ama nke ọbara mgbali elu. Ọgwụ nwere akụ hypotensive, a na-ahọrọ usoro onunu ogwu maka onye ọrịa ọ bụla. Tupu ị takingụ ọgwụ ahụ, a na-atụ aro ka ọ gụọ ntuziaka maka ya, ịmụ ọgwụ mgbochi, yana mmetụta ndị ọzọ.

Ngwakọta nke ọgwụ "Mikardis"

Ihe na-arụ ọrụ, nke bụ isi bụ ihe mepụtara learism, bụ telmisartan. Otu mbadamba nwere ike ịnwe milligrams 20 ruo 80. Ngwa ndị ọzọ na - enyere aka ịbanye ngwa ngwa nke ugbu a bụ:

• yoxitalamic acid
• sodium hydroxide
• polyvinylpyrrolidone,
• glucite
• stereta magnesium.

Oge mbu nke "Mikardis" na-eduga n'itinye nwayọ nke ọbara mgbali elu. O jiri nwayọ belata n’ime ọtụtụ awa. A na-ahụ mmetụta antihypertensive otu ụbọchị mgbe ị takingụsịrị ọgwụ ahụ.

Nke a pụtara na iji nọgide na-enwe ọbara mgbali nkịtị, ọ dị mkpa iji otu mbadamba Mikardis kwa ụbọchị. Enwere ike ịhụ mbelata nke nrụgide kachasị ukwuu mgbe ọnwa gasịrị site na mmalite ọgwụ.

Site na njiri siri ike iwere "Mikardis" ọ nweghị mmetụta nke "kagbuo", ndị na-egosi mbụ na-alaghachi n'ime izu 2-3.

Ihe niile mejupụtara ọgwụ ahụ, mgbe a na -ewere ya ọnụ site na eriri afọ, na-etinye obi gị dum ngwa ngwa, mkpokọta kachasị nke ihe ndị dị n'ọrụ ruru ihe ruru 50%.

Etu esi ewere ogwu a?

N'ọnọdụ ndị a na-adịghị ahụkebe, a na-enye ọgwụ ahụ maka ndị ọrịa karịrị afọ 55, bụ ndị nọ n'ihe ize ndụ nke ịmalite ọrịa obi obi jikọtara ya na ọbara mgbali elu.

Na mgbakwunye na "Mikardis" mbụ, a na-emepụta ọgwụ "Mikardis gbakwunyere". Nke ikpeazụ a nwere milligram 12.5 nke hydrochlorothiazide, nke nwere akụrụngwa diuretic.

Nchikota ọgwụ diuretica na anonistensin antagonist na - enyere aka inweta oke. Diuretic na-amalite ịpụta ka elekere abụọ gachara ọgwụ ọjọọ. Edere "Mikardis gbakwunyere" ma ọ bụrụ na ọ gaghị ekwe omume nweta mbelata nrụgide mgbe ị na-ewere "Mikardis".

N'ọnọdụ ọ bụla ịkwesịrị ị drugụ ọgwụ na usoro onunu ogwu gị, ebe ọ bụ naanị dọkịta na-aga ya kwesịrị ịchọpụta ọgwụ mgbochi niile ma nyocha nyocha nke onye ọrịa.

Mikardis n'oge di ime

Ọmụmụ ihe omimi nyochaputala mmetụta fetotoxic nke ọgwụ. Ya mere, apughi iburu "Mikardis" na udu onyunyo niile n’oge a na-ete nwa. Ọ bụrụ na nwanyị chọrọ ịbụ nne, ndị dọkịta na-enye ndụmọdụ ka ọ gbanwee ka ọgwụ ndị na-adịghị ize ndụ. Mgbe ime ime, a kwụsịrị ị theụ ọgwụ.

Etu esi ewere ọgwụ "Mikardis"?

Ọ bụ naanị dọkịta ka o nyere ọgwụ ahụ ma ọ nwere ike iji ya rụọ ọrụ onwe ya yana ọgwụ ndị ọzọ maka ebuli ịrụ ọrụ nke sistem obi. Russian Mikardis analogues nwere otu ụdị ọrụ ahụ.

Ntụziaka eji eme ihe na-egosi na ị intụ ọgwụ kwa ụbọchị kwesiri ịdị naanị otu mbadamba 40 milligrams.

Ekwesịrị icheta na n'ime ndị ọrịa nwere ụdị ọbara mgbali elu, mbelata ọbara mgbali na-apụta mgbe ị na-ewere mbadamba nkume nwere milligrams 20 nke ihe na-arụ ọrụ. A na-eme nhọrọ nke usoro ọgwụgwọ ọgwụgwọ oge ruo izu anọ.

N'ezie, ọtụtụ oge dị mkpa maka Mikardis iji gosipụta mmetụta ya niile dị n'ahụ ahụ onye ọrịa.

Ọ bụrụ na n'ime ọnwa iwere "Mikardis 20" nsonaazụ ahụ achọrọ abịaghị, dọkịta depụtara ọgwụ iji ọgwụ ruru 80 milligram, nke dịkwa mkpa ị beụ otu mbadamba ụbọchị.

N'okwu ndị siri ike nke ọrịa ahụ, dọkịta nwere ike ịkọpụta "Mikardis" na usoro nke milligrams 160, ya bụ, ị ga-ewere mbadamba 2 kwa ụbọchị, 80 milligrams.

N’ọnọdụ ndị a na-adịghị ahụkebe, onye na-arịa ọrịa anaghị adalata ọbara mgbali elu dị ka otu ọgwụ, mgbe ahụ ka edepụtara onye ọrịa dị otú ahụ "Mikardis gbakwunyere", n'ihi nke mgbali ahụ na-ebelata ngwa ngwa. Usoro nke ị drugụ ọgwụ ahụ n'ọnọdụ a ka ahọrọ site na mmepe nke ọbara mgbali elu. Nyocha banyere "Mikardis" na analogues gosipụtara mmetụta dị mma ya na iwetulata ọbara mgbali elu.

Ndị ọrịa nwere akụkọ gbasara ahụike ya na-arụ ọrụ anaghị achọ nhọpụta usoro ọgwụgwọ nke otu onye.

Ọ bụrụ na ozi a nwere ndekọ banyere ọghọm ọnya ọgbụgba nke ọrịa imeju, mgbe ahụ onye ọrịa ga-ewererịrị "Mikardis 40".

Nweghị ike ịba ụba dose ọgwụ a: nke a nwere ike ibute arụ ọrụ akụrụ na imeju. Ndị ọrịa merela agadi adịghị edozi usoro ọgwụgwọ ahụ.

N'ime ndị ọrịa nwere mellitus ọrịa shuga, yana ọrịa obi na akwara obi ma ọ bụ ọrịa obi ndị ọzọ, ohere nke infarction myocardial na-egbu egbu na ọnwụ mberede na-abawanye n'ihi iji ọgwụ Mikardis.

Ọrịa obi obi na-arịa ọrịa shuga mellitus nwere ike ime n'enweghị ihe mgbaàmà ma enweghị ike ịchọpụta ya na mbido. Ya mere, tupu ịmalite ọgwụgwọ na ọgwụ Mikardis, ị ga-agabiga ule niile dị mkpa ma gaa nyocha.

Ike ijikwa usoro mgbagwoju anya mgbe ị na-ewere "Mikardis gbakwunyere" na analogues

Ntụziaka maka ojiji na-egosi na emebeghị nnyocha pụrụ iche etu esi arụ ọrụ (telmisartan), nke bụ akụkụ nke ọgwụ na ọtụtụ analogues, na-emetụta ntinye uche na ike ịkwọ ụgbọala. Mana! Ekwesịrị icheta na ọgwụ nwere ihe ndị mejupụtara diure nwere ike ibute iro ụra na nkụ.

Ọgwụ a "Mikardis" ga-echekwara ya ebe ụmụaka agaghị enweta ya, na-enweghị ogo 30. Ndụ shelf:

1. Mbadamba ụrọ nwere ogwu nke 40 na 80 milligrams - afọ 4.
2. Mbadamba nwere usoro ogwu nke 20 milligrams - afọ 3.

A na-enye ọgwụ ọgwụ ike dabere na ndenye ọgwụ ahụ. Amachibidoro "Mikardis" maka ụmụaka na-erubeghị afọ 18.

Mikardis: analogues, nyocha

Ntụziaka maka iji ya kwuo na ị nwere ike ị theụ ọgwụ ahụ n’oge ọ bụla n’ụbọchị, iri nri anaghị emetụta ikike ahụ mmadụ iji nweta ọgwụ ahụ.

Oge ngụkọta ọgwụgwọ ahụ dabere na dọkịta, mgbe ọ tụlechara ahụike onye ọrịa, dọkịta ahụ nwere ike ịkwado ịtụgharị ka ọ dị miligram abụọ.

Ndị na-a theụ ọgwụ ahụ na-achọpụta mbelata ọbara mgbali ngwa ngwa na enweghị ọghọm ya. Mana ọnụ ọgụgụ ka ukwuu nke ndị ọrịa ịzụta ọgwụ a bụ ọnụ ahịa dị elu na-akwụsị ya.

Dọkịta ahọpụtara ụdị analogues ndị dị ọnụ ala karịa "Mikardis gbakwunyere", ọgwụ ndị ama ama nwere mmetụta yiri ya gụnyere:

Pricegwọ nke analogues nke ọgwụ Mikardis dabere na mba mepụtara yana ihe mejupụtara ọgwụ ahụ. Na ego dị ala, ị nwere ike ịzụta ihe analogues ndị a:

1. Blocktran bụ ọnụọgụ dị ọnụ ala ma na-akwụkwa ụgwọ maka ọgwụgwọ ọbara mgbali elu na nkụchi obi na-adịghị ala ala.Ọ dị iche na Mikardis na akụrụngwa na usoro onunu ogwu.
2. A na - emepụta “Valz” - ngwugwu nke mbadamba 28, nke karịrị nnọọ ọgwụ “Mikardis”, yabụ, na ọgwụgwọ ogologo oge, “Valz” dị ọnụ ala. Nhazi nke ọgwụ dị iche iche, ebe ọ bụ na a na-eji Valsartan (40 milligrams) na Valz.
3. "Angiakand" - dị iche na mejupụtara, ihe na-arụ ọrụ na-arụ ọrụ na usoro ya. A na-ahapụ ya ka ọ were ọbara mgbali elu na obi daa ọrịa. Ọ nwere contraindications ndị ọzọ, yabụ na-atụ aro ka ị jiri nlezianya gụọ ntuziaka tupu ojiji.

Mikardis Plus: ntuziaka maka ojiji, analogues

Ọgwụ "Mikardis gbakwunyere" bụ maka ọgwụgwọ nke ọrịa obi na iji belata onwu. E gosipụtara ya maka ọrịa myocardial n'etiti ndị gbara afọ 55-60. A kọwara ọgwụ a kọwara na Germany. Tupu ojiji, ịchọrọ ndụmọdụ dọkịta, nyocha zuru ezu nke data banyere akụrụngwa na njirimara, nke nwere ntuziaka maka iji ọgwụ Mikardis.

Ngwakọta, usoro nke ime ihe na ụdị ntọhapụ

Ọgwụ dị n'ụdị mbadamba ọcha nke whitish nwere njiri mara ụlọ ọrụ n'otu akụkụ, na nke abụọ - ya na “51N” ma ọ bụ “52N”, dabere na usoro onunu ogwu. N'ime ngwugwu kaadiboodu, ọgwụ nwere ike ịnwe efere 2 ruo 8 nwere mbadamba 7 n’ime nke ọ bụla. Ngwakọta nke otu mbadamba "Mikardis" gụnyere ihe ndị egosipụtara na tebụl ha.

Nkọwa nke metụtara 21.08.2014

• Aha Latin: Micardis
• Koodu ATX: C09CA07
• Arụ Ọrụ: Telmisartan (Telmisartan)
• Emeputa: BOEHRINGER INGELHEIM PHARMA (Germany)

Otu mbadamba Micardis nwere 40 mg ma ọ bụ 80 mg telmisartan (ike ihe).

Ndị e mere: sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.

Dodoụbiga ya ókè

Edebanyeghị okwu n ’ịdoụ ọgwụ gabigara ókè.

Mgbe ihe mgbaàmà dịka: ọbara mgbali elu, tachycardia, bradycardia, ọgwụgwọ Symptomatic chọrọ. Ọkpụkpụ anụ ahụ adịghị arụ ọrụ.

Ntụziaka pụrụ iche

N'ihe banyere ịdabere na olu akwara na ọrụ akụrụ na-arụkarị ọrụ RAAS (dịka ọmụmaatụ, na ndị ọrịa nwere ọrịa obi na-adịghị ala ala ma ọ bụ ọrịa akụrụ, gụnyere ọrịa akwara ma ọ bụ stenosis akwara), iji ọgwụ eme ihe na-emetụta usoro a nwere ike. esonyere mmepe nke nnukwu akwara ọbara, hyperazotemia, oliguria ma, n'ọnọdụ ndị adịghị obere, nnukwu akwara na-ada ada.

N'ime ụfọdụ ndị ọrịa, n'ihi nnabata nke RAAS, ọkachasị mgbe ị na-eji mkpokọta ndị ọrụ na-arụ ọrụ na sistemụ a, ọrụ akụrụngwa (gụnyere nnukwu gbasara akụrụ akwara). Ya mere, usoro ọgwụgwọ a na - esochi ya na mgbochi abụọ nke RAAS yiri (dịka ọmụmaatụ, na mgbakwunye nke ACE inhibitors ma ọ bụ onye na - egbochi renin inhibitor, aliskiren, na angiotensin II receptor antagonist blockers), kwesịrị ka ejiri nlezianya rụọ ọrụ na nlezianya banyere ọrụ akụrụ. serum creatinine).

N'ime ndị ọrịa nwere ọrịa mellitus na ọrịa obi ọgụ, dịka ọmụmaatụ, n'ime ndị ọrịa nwere ọrịa mellitus na ọrịa obi, ojiji nke ọgwụ ndị na-ebelata ọbara mgbali, dịka ndị na-anabata antagonist angio ma ọ bụ ndị na-egbochi ACE, nwere ike ịbawanye n'ihe ize ndụ nke infarction myocardial infarction na mberede obi. ọnwụ nke akwara. N'ime ndị ọrịa nwere ọrịa shuga, ọrịa obi na-arịa ọrịa obi nwere ike ịbụ asymptomatic ya mere ya agaghị enwe ike ịchọpụta ya. Tupu ịmalite iji ọgwụ Mikardis maka nchọpụta na ọgwụgwọ nke ọrịa obi, ọ ga-abụrịrị usoro nyocha kwesịrị ekwesị, nwalee ya na mmega ahụ.

Dabere na ahụmịhe nke iji ọgwụ ndị ọzọ na-emetụta RAAS, mgbe ị na-edepụta Mikardis na potassium-sparing diuretics, ihe ndị ọzọ na-enye potassium, nnu a na-a potassiumụ n’ime ya, na ọgwụ ndị ọzọ na-eme ka ịbawanye uru nke potassium na ọbara (dịka ọmụmaatụ, heparin), a ga-enyocha ihe ngosi a na ndị ọrịa.

N'ime ndị ọrịa nwere ọrịa mbụ aldosteronism, ọgwụ antihypertensive, usoro nke ime ya bụ mgbochi nke RAAS, anaghị adịkarị mma.

N'aka nke ọzọ, enwere ike iji Mikardis mee ihe na njikọta thiazide, dị ka hydrochlorothiazide, nke gbakwunyere nwere mmetụta hypotensive (dịka ọmụmaatụ, Mikardis Plus 40 mg / 12.5 mg, 80 mg / 12.5 mg).

Ekwesịrị ịkpachara anya mgbe ị na-eji ọgwụ Mikardis (yana vasodilators ndị ọzọ) na ndị ọrịa nwere aortic ma ọ bụ mitral stenosis yana ọrịa cardiomyopathy hypertrophic.

N'ime ndị ọrịa nwere nnukwu ọbara ọgbụgba, ọnụọgụ telmisartan 160 mg / ụbọchị yana njikọta hydrochlorothiazide 12.5-25 mg dị mma ma anabata ya nke ọma.

A na - ekekarị Telmisartan na bile. N'ime ndị ọrịa nwere mgbochi ọrịa biliary tract ma ọ bụ ọrịa imeju, enwere ike ịtụ anya mbelata nke ị theụ ọgwụ ahụ.

Dysfunction of the imeju na mgbe a na-ahọpụta telmisartan n'ọtụtụ ikpe ka a hụrụ n'etiti ndị bi na Japan.

Mikardis adịkarịghị irè na ndị ọrịa nke agbụrụ Negroid.

Mkparịta ụka ọgwụ ọjọọ

Mgbe ị na-eji ọgwụ ahụ, ọ dị mkpa iburu n'uche nnabata mmekọrịta gị na ọgwụ ndị ọzọ:

1. Telmisartan nwere ike iwelie mmetụta hypotensive nke ndị ọrụ antihypertensive ndị ọzọ. Achọpụtaghị ụdị mmekorita ndị ọzọ na mkpa ọgwụgwọ.
2. Site na iji telmisartan na ramipril na-eme n'otu oge, a hụrụ mmụba nke okpukpu abụọ na AUC0-24 na Cmax nke ramipril na ramipril. Egosipụtaghi mkpa ogwu di egwu a.
3. Ihe jikọtara ya na digoxin, warfarin, hydrochlorothiazide, glibenclamide, ibuprofen, paracetamol, simvastatin na amlodipine anaghị eduga na mkparịta ụka dị egwu na ụlọ ọgwụ. Mmụba dị ịrịba ama na nkezi nke digoxin na plasma ọbara site na nkezi 20% (n'otu oge, pasent 39%). Site na nlekọta nke telmisartan na digoxin, ọ bụ ihe amamihe dị na ya ikpebi oge ịhapụ digoxin n'ọbara.
4. Ọgwụ NSAIDs, gụnyere acetylsalicylic acid, ndị na-egbochi COX-2, na ndị na-adịghị ahọpụta NSAID, nwere ike ibute nnukwu ọrịa gbasara akụrụngwa na ọrịa ndị akpọnwụ akpịrị. Ọgwụ na-eme ọgwụ na RAAS nwere ike inwe mmetụta synergistic. N'ime ndị ọrịa na-anata NSAIDs na telmisartan, BCC ga-akwụghachi ụgwọ na mbido ọgwụgwọ ya ma a ga-eme nyocha banyere ọrụ akụrụ.
5. N'iji oge nke ACE inhibitors na nkwadebe lithium, a hụrụ mmụba mbugharị nke mkpokọta lithium n'ọbara, yana mmetụta nsonaazụ. N'ọnọdụ ndị a na-adịghị ahụkebe, a kọọrọ mgbanwe ndị dị otú ahụ na nchịkwa nke ndị na-emegide nnabata angiotensin II. Site na nhazi nke lithium n'otu oge na antagonensin II na-emegide antagonist, a na-atụ aro iji chọpụta mkpo lithium n'ọbara.
6. Mbelata mmetụta nke ndị na - egbochi ọgwụ mgbochi, dị ka telmisartan, site na igbochi mmetụta vasodilating nke prostaglandins ka a hụrụ na NSAIDs.

Anyị nwetara nyocha ụfọdụ nke ndị na-a Mikụ ọgwụ Mikardis:

1. Natalya. Amjọ jidere m. Adị m afọ 59. Ọbara mgbali elu Mgbe ị na-a theụ ọgwụ ahụ, ụkwụ ya malitere 'ịmaba', ọ na-eme mkpesa na dọkịta, ọ malitere na-esi ọnwụ na ọ ga-aga n'ihu ị takeụ ọgwụ ahụ, na-ekwu na ọnụ ọgụgụ nrụgide ahụ dị mma. Atụkwasịrị m okwu ndị dọkịta a obi. Aka bidoro “buzz”. Jọ tụrụ m (otu ọnwa na ọkara nke ọgwụgwọ gafere). Kwụsị ị takingụ ọgwụ. Aka ‘daa jụụ’, ụkwụ kubie ume ọnwa atọ.
2. Catherine. Onye dọkịta depụtara Mycardis. Na mbido, usoro onunu ogwu ya di 40 mg, mgbe ahu onodu ya bawanye na 80. Ogwu ahu nyere aka kwusi mmepe nke obara, mmetuta ugha gosiputara n’odide oge iwe. Aga m aga n’ihu inwe obi uto n’imeso Mikardis, mana nnukwu ego ya riri m ike. Dọkịta tiputara analogue dị ọnụ ala.
3. Semen. Mgbe nkụchi obi gasịrị, enwere m nkụda mmụọ na ọnya ọbara, dibia maka dibịa ya nyere ọgwụ a. M na-a itụ ya kemgbe otu afọ.Otu ọnwa mgbe iwere ya, nrụgide ahụ kwụsịrị, ọ ghọrọ ihe nkịtị - 120/70. Ugbu a Mikardis na-a wifeụ nwunye ya na nwanne ya nwanyị.

Anakpụrụ nke analogues nke na-arụ ọrụ:

Tupu iji analogues, gwa dọkịta gị.

Ọnọdụ nchekwa na ndụ nchekwa

Na-echekwa n'ebe ọkpọkọ na-erughi ụmụaka aka na ọnọdụ okpomọkụ na-erughi + 30 Celsius С.

Mikardis bụ ọgwụ gbasara ọrịa obi.
Ọ mejupụtara ihe ndị a dị ka telmisartan, sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.
Ihe mejupụtara ọgwụ ahụ na-eme ka mgbasawanye nke akwara ọbara, nke na-ebelata ọbara mgbali. Ọgwụ dị oke irè, ihe ọ na - eme bụ mgbe awa ole na ole gasịrị.

Registered debara aha ọgwụ ahụ?: lelee ☜

Medicine gbakwunyere: 2010-03-11.
Ntụziaka emelitere: 2017-08-25

Analogs na nnọchi

☠ Ntị! Medicinesmụ ọgwụ ọgwụ nwanyị - ka esi agbakọta ndị Russia ma ọ bụ ego na-ekwesịghị iji emefu!

Ntụziaka dị mkpirikpi maka iji, contraindications, ihe mejupụtara

Ihe ngosiputa (gini na - enyere aka?)
Ejiri ya n'ọtụtụ ebe iji na-agwọ ọbara mgbali elu. A na-ejikarị ya eme ihe mgbochi, maka ndị agadi, iji belata ọrịa nke usoro obi.

Ihe ngbanwe
Amachibidoro ya iwu iji mycardis mgbe:
1. onye ọrịa nwere ọrịa imeju,
2. pụrụ iche nghọta site na ahu nke fructose na lactose,
3. mgbochi afọ (ndị na-eto eto na-erubeghị afọ iri na asatọ),
4. n’oge ime na n’ara,
5. enwere ọrịa nke biliary tract.
N’inye nlezianya pụrụ iche, a na-enye ndị ọrịa iwu maka ọrịa akụrụ, maka hyponatremia, maka hyperkalemia, maka akụrụ mgbe oge ntụgharị, maka nnukwu nkụchi obi, maka ụdị stenosis dị iche iche.

Ofzọ nke ngwa (usoro onunu ogwu)
Mbadamba nkume a na-ede ede, n'agbanyeghị nri a ga-eri. Usoro ogwu a ka atọrọla onwe ya maka onye ọrịa ọ bụla, oge a na-agwọ ya dị ogologo. Na ọgwụgwọ nke dose bụ otu ọgwụ otu ugboro n’ụbọchị, ọ bụrụ na ọ dị mkpa, enwere ike okpukpu abụọ.

Ingsdọ aka na ntị
A machibidoro iji mycardis na aliskeren (maka ọrịa shuga). Ọ baghị uru ijikọ ya na ọgwụ nwere lithium.

Nsonaazụ
Mikardis kpatara otutu ihe ndi ozo:
1. ọrịa akụkụ okuku ume na elu,
2. Cystitis
3. anaemia,
4. nsogbu ehighị ụra, ịda mba n’obi, nchekasị,
5. enweghi ike ịhụ ụzọ,
6. mbelata nke ọbara mgbali elu,
7. bradycardia, tachycardia,
8. ike ọgwụgwụ, mkpụmkpụ ume,
9. afọ mgbu, flatu, afọ ọsịsa.
10. akọrọ ọnụ, ọgbụgbọ, ọgbụgbọ,
11. Mmeghachi omume nfụkasị (ọnya, urticaria, itching),
12. Ahụ mgbu, akpụ ụkwụ,
13. arụrụ ọrụ na-arụ ọrụ gbasara arụrụ, ruo n'ịrụ oke akwara,
14. mgbu na mpaghara obi na adịghị ike nke anụ ahụ.

Dodoụbiga ya ókè
Onweghi okwu ịdoụ ọgwụ ọdoụ .ụ riri nne.

Mpempe mwepụta
A na-emepụta ya n'ụdị mbadamba, ọcha, oblong, na ngwugwu ọnya nke 7 nkeji.

Aro / nyocha nke ndi dibia: anyị nwere ngalaba dị ukwuu maka ịgagharị na weebụsaịtị anyị, ebe a na-atụle Mikardis ọgwụ ahụ otu oge site na ndị ọrịa na ndị dọkịta - lee

Mikardis - ọgwụ maka igbochi ọrịa obi

"Mikardis" bụ ọgwụ mepụtara na ntọala nke ihe pụrụ iche arụ ọrụ /

Ọ bụ ụzọ dị irè e si emegide ndị na-anabata angiotensin.

Ngwongwo ọgwụ a na-enye gị ohere iji nwayọ emetụta ahụ mmadụ ma nye nsonaazụ kachasị na ọgwụgwọ nke ọrịa.

1. Ntụziaka maka ojiji

Taa, a na - eji "Mikardis" mee ihe n'ọtụtụ ọgwụ. Ọ bụ ndị dọkịta depụtara ọgwụ ndị a iji gwọọ ọrịa dị iche iche.

Dịka ntuziaka ahụ si dị, enwere ike ị drugụ ọgwụ ahụ n'ọnọdụ ndị a:

Mkpa ọgwụgwọ maka ndị ọrịa na-ata ahụhụ site na ngosipụta nke ọbara mgbali elu dị mkpa.

1. Maka ọgwụgwọ nke ọrịa dị iche iche nke usoro akwara obi (maka ndị nwere ọrịa shuga, yana ndị metụtara ọgwụgwọ ọnya afọ ma ọ bụ ọrịa obi).
2. Iji gbochie ihe egwu nke ọdịdị nke otu ọrịa obi.

2. Usoro ọgwụgwọ na nhazi

Ekwesịrị iji mbadamba Mikardis naanị ọnụ, ebe ha na-a drinkingụ nnukwu mmiri ọ drinkingụ drinkingụ nkịtị. The Tụ ọgwụ anaghị adabere n’oge iri nri.

Site n'ọbara mgbali elu, a na-adụ ndị ọrịa ọdụ ka ha họrọ usoro izizi ọgwụ a, nke agaghị agafe 40 mg kwa ụbọchị. N'ọnọdụ ụfọdụ, iji ụdị ọgwụ a, ọ gaghị ekwe omume iji nweta ọgwụgwọ ọgwụgwọ a chọrọ, ya mere, ọ dị mkpa ka iwelie ọgwụ ahụ gaa na 80 mg otu ugboro n'ụbọchị.

Ọ dị mkpa iburu n'uche eziokwu ahụ bụ na ọgwụ ọgwụ ike kachasi ike na-apụta naanị ọnwa 1-2 ka mmalite ọgwụgwọ.

Iji belata ohere nke ọrịa obi, dịka iwu, ndị ọrịa na-ewere mbadamba 80 mg kwa ụbọchị n’otu ọgwụ. Maka ụfọdụ ndị, na mmalite nke usoro, ịgbazi ọbara ọgbụgba nwere ike ịdị mkpa.

Ndị mmadụ na-arịa arụ ọrụ akụrụ nwere nsogbu ịhọrọ ọ bụla.

Maka ndị ọrịa nwere ọrịa imeju na-arụ ọrụ nke ọma, usoro a na-atụ aro kwa ụbọchị anaghị agafe 40 mg otu ugboro n'ụbọchị.

Kwa afọ na Russia, a na-eme ndekọ banyere nchọpụta ahụ - angina pectoris. Muta ihe banyere oria na ọgwụgwọ oria a:

1. Zọ ọgwụgwọ ọgbara ọhụrụ.
2. Ihe nrịba ama nke angina pectoris.

A na-eme Mikardis n'ụdị oblong, obere mbadamba ihe na-acha ọcha ma ọ bụ na-acha ọcha.

Ejiri ihe ndị a dị ka ọgwụ nke ọgwụ a:

1. Telmisartan bụ ihe na-arụ ọrụ.
2. Ndị pụrụ iche: magnesium stearate, povidone, sorbitol, sodium hydroxide, meglumine.

4. Mmekọrịta na ọgwụ ndị ọzọ

Ogwu nwere ike iji otutu ogwu ozo mekorita otutu ihe, ma n’enye ihe kwesiri ekwesi:

1. N'ihe banyere mbadamba mbadamba na ọgwụ ọ bụla ọzọ, ọgwụ mmụba ga-abawanye na mmetụta nke ọdịdị hypotensive.
2. Njikọ ya na ọgwụ dịka Warfarin, Digoxin, yana Paracetamol ma ọ bụ Ibuprofen anaghị arụpụta arụmọrụ ọ bụla dị mkpa.
3. Mgbe eji ọgwụ ọgwụ nwere ramipril mee ihe n'otu oge, itinye uche nke ikpeazụ na ọbara nwere ike ịba ụba.
4. Ọ bụrụ na a na-eme ọgwụgwọ ejikọtara site na iji Mikardis na angiotensin dị iche iche na-agagharị enzyme inhibitors, yana ọgwụ ndị gụnyere lithium, a na-achọpụta mmụba dị ukwuu nke ihe a na-ahụ n'ọbara, nke nwere mmetụta ọkụ na ahụ mmadụ.
5. Njikọ ogologo oge na ọgwụ mgbochi mkpali na - abụghị steroidal (NSAIDs na - ahọrọghị, Acetylsalicylic acid na ọtụtụ ndị ọzọ) na - akpata mmepe kpụ ọkụ n'ọnụ nke akụrụngwa akwara na - akpata nnukwu mmerụ ahụ nke ndị mmadụ na - arịa nkụda mmụọ.
6. Ọgwụ na-eme ihe na sistemụ renin-angiotensin-aldetsterone na-enwekarị mmekọrịta.

5. Nsonaazụ

Ọgwụ a na - enye gị ohere ị nweta nsonaazụ kwụsiri ike n'ọgwụgwọ ọgwụgwọ ọbara mgbali elu ma ọ bụ ọrịa obi.

Agbanyeghị, enwere ọtụtụ contraindications, na ọnụnọ nke ọ dị mkpa ịhapụ iji mbadamba ma dochie ọgwụ ọzọ:

1. Ngosiputa nke nnabata ndi mmadu n’ime ihe obula eji eme ihe maka mbadamba mbadamba.
2. Ọnụnọ nke ọrịa dị iche iche na-egbochi ọnya biliary.
3. Nkwekọrịta e ketara eketa n’ihe dị ka fructose.
4. Esemokwu doro anya na arụ ọrụ nke imeju.
5. Ndị ọrịa na-erughi afọ iri na asatọ n’oge ọgwụgwọ.
6. Mụ nwanyị na-agba ara na ebe a na-ebe akwa.

Enwekwara ọnya na ọnụnọ ọrịa nke ekwesịrị iji Mikardis jiri nlezianya na n'okpuru nlekọta nke dọkịta. Ndị a gụnyere:

1. Arụ ọrụ akụrụ.
2. Achịcha ọrụ nke imeju.
3. Streosis akwara na-amụrụ otu ọrịa.
4. Mgbakwụnye mgbidi abụọ.
5. Ọrịa obi na-adịghị ala ala.
6. Mmepe nke hypernatremia ma ọ bụ hyperkalemia.
7. Ọkpụkpụ ọbara na-erugharị n’arụ ọbara mere maka ọtụtụ ebumnuche.
8. Mgbidi nke valvụ mitral.
9. Ihe ịrịba ama nke aortic valve stenosis.
10. Emechara ịwa ahụ maka ntụgharị akụrụ.
11. Aldosteronism nke izizi.
12. Hypertrophic idiopathic subaortic stenosis.

Mmetụta ndị ọ na-enwekarị na-eme, ma ha anaghị adịte aka, ha na-apụkwa n'anya ngwa ngwa.

Ma ọ bụghị ya, ịkwesịrị ịhapụ ọgwụ a. Ha bụ:

1. Sepsis.
2. Ihe ịrịba ama nke thrombocytopenia.
3. Mmepe nke eosonophilia.
4. O doro anya na anaemia.
5. Mkpesa nke ehighị ụra nke ọma.
6. Ike ike.
7. Mmepe nke ọbara ọgbụgba orthostatic.
8. Mbelata dị egwu nke ọbara mgbali.
9. Na ọgbụgbọ na vomiting.
10. Tachycardia nwere brachycardia.
11. Ntutu ume.
12. Ngosiputa adighi anya.
13. Ugboro ugboro.
14. Mgbu siri ike n’ime afọ.
15. Akpukpo ahihia nke onu mucous nke onu.
16. Eterbelata ọrụ imeju.
17. Nkpughe nke ihe iriba ama nke mmeghachi omume akpaka.
18. Guzoputa anakpo angioedema kwesiri ngosi.
19. Ihe omimi.
20. Ọrịa dyspepsia siri ike.
21. Mmepe nke eczema.
22. Agba ya n’ahụ, ọkụ na-atọ ya ụtọ.
23. Ngosipụta nke ogbu na nkwonkwo.
24. Ihe mere ihe mgbu na otu akwara dị iche iche.
25. Ngosipụta ndị ọzọ na-emebi ọrụ niile dị n’ime ahụ mmadụ.

6. Usoro na ọnọdụ nchekwa

Ekwesịrị ịchekwa Mikardis n'ebe ọkpọka nwere ikuku ikuku dị ala, nke a na-enyocha ya mgbe niile ma bụrụ onye a pụrụ ịdabere na ya site na ìhè anyanwụ. Ọgwụ ekwesịghị ịdị ụmụaka aka.

Ndụ shelf ọgwụ a bụ afọ abụọ.

Na ụlọ ahịa ọgwụ dị n'ókèala nke Russian Federationmbadamba nkume na-eri site na 300 rubles kwa ngwugwu.

Na ụlọ ọgwụ ndị Ukraine ọnụahịa ha sitere n'ihe dị ka hryvnia 115.

Ihe atụkarịkarị ọgwụ a gụnyere ndị a:

Nyocha banyere ọgwụ Mikardes na-adịkarị mma, ndị ọrịa na-achọpụta nsonaazụ dị mma nke mmetụta ọgwụ ahụ nwere n'ahụ ahụ, dịka ọmụmaatụ Alina dere, sị: “Ọgwụ dị mma. Ọ bụ site na enyemaka ya ka m wepụrụ ọbara mgbali dị mkpa. Ahụghị m mmetụta ọ bụla. M na-akwado ya maka onye ọ bụla na-enweghị ihe mgbochi ahụ. ”

Alena: “Nkwadebe dị nro. Dọkịta ahụ tiri iwu maka mgbochi ọrịa obi. Enwere m mmasị na nsonaazụ ahụ. ”

Nwere ike ịmatakwu banyere nyocha ndị ọrụ ndị ọzọ, kọọkwara echiche gị na njedebe nke edemede.

Edere ọgwụ Mikardes maka ịgwọ ọtụtụ ọrịa obi. Edeghị ọgwụ ahụ n’oge ịtụrụ ime, mmebi iwu nke imeju na akụrụ, n’oge ime. Iji zere mmetụta ndị ọ ga-ekwe omume na ịdoụbiga mmanya ókè, a ghaghị ị takenụ ọgwụ ahụ na nkwenye dọkịta.

Otu mbadamba Micardis nwere 40 mg ma ọ bụ 80 mg telmisartan (ike ihe).

Ndị e mere: sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.

Mpempe mwepụta

Ọgwụ bụ mbadamba ihe na-acha ọcha na-acha uhie uhie nwere ihe osise 51H nke dị n'otu akụkụ na akara ụlọ ọrụ dị na nsọtụ ọzọ.

7 ụdị mbadamba ụrọ nke nwere 40 mg na paịlị; 2 ma ọ bụ 4 na blisters dị na igbe kaadi. Edide 7 dị mbadamba ụrọ dị otú a na-a ofụ ọgwụ dị 80 mg na chara acha, 2, 4 ma ọ bụ 8 na blisters dị otú ahụ na igbe kaadi.

Omume ọgwụ

Mgbachi angiotensin II n'ihi ya, vasodilation. Ọgwụ ahụ na-ebelata ọbara mgbali elu, afọ ojuju aldosterone n’ime ọbara.

Pharmacodynamics na pharmacokinetics

Mlọ ọgwụ

Telmisartan - ihe na - ahọrọ ihe nnabata angiotensin II. Nwere nnukwu ebe ije dị AT1 ụdị nnabata angiotensin II. Asọmpi na angiotensin II na ndị nnabata kpọmkwem na-enweghị otu mmetụta. Njikọ ahụ na-aga n'ihu.

O gosiputaghi ikpo oku maka ihe ndi ozo nke nabata ya. Na-ebelata ọdịnaya aldosterone n'ọbara, anaghị egbochi plasma renin na ọwa ion n’ime sel.

Bido mmetụta hypotensive A hụrụ n'ime elekere atọ izizi mgbe nchịkwa gasịrị telmisartan. Omume ahụ dịgide otu ụbọchị ma ọ bụ karịa. Nkwupụta akpọrọ ahụ na-etolite otu ọnwa mgbe nchịkwa na-aga n'ihu.

N'ime ndị mmadụ na- ọbara mgbali iketelmisartan na-ebelata systolic na ọbara mgbali ọbara, mana anaghị agbanwe ọnụọgụ nke obi obi.

Ọ naghị akpata ọrịa wepụ ego.

Mlọ ọgwụ

Mgbe a na -ewere ya okwu ọnụ, ọ na-abanye na eriri afọ ngwa ngwa. Bioavailability na-erute 50%. Mgbe awa atọ gachara, plasma ịta ga-akachasị. 99.5% nke ihe arụ ọrụ na-egbochi protein protein.

Metabolized site na nzaghachi na acid glucuronic. Metabolites nke ọgwụ ahụ anaghị arụ ọrụ. Iwepu ọkara ndụ dị ihe karịrị awa iri abụọ.

A na-ewepụta ya site na ngwara, digesion na mmamiri erughị 2%.

Ihe ngosi maka ojiji

Ihe ngbanwe

Mpempe akwụkwọ Micardis na-egbochi ndị mmadụ iche iche allergies n'ihe ndị dị na ọgwụ ahụ, dị arọ ọrịaimeju ma obu akụrụ, fructose anabataghị ya, n'oge ime na lactation, ụmụaka ndị gbara afọ 18.

Nsonaazụ

• Site na usoro ụjọ ahụ: ịda mbaanya ntughari isi ọwụwaike ọgwụgwụ, nchekasị, ehighi ura, ogwe.
• Site na usoro iku ume: ọrịa nke akụkụ okuku ume na elu (sinusitis, pharyngitis, ọla kọpa), ụkwara.
• Site na sistemụ mgbasa: ekwuputala mbelata nke nrụgide, tachycardia, bradycardiaobi mgbu.
• Site na usoro digestive: ọgbụgbọ, afọ ọsịsa, dyspepsiaịba ụba ịta nke enzymes imeju.
• Site na usoro mọzụlụ: myalgiaobere azụ mgbu arthralgia.
• Site na usoro genitourinary: edema, ọrịa nke usoro genitourinary, hypercreatininemia.
• Mmeghachi omume Hypersensitivity: Skin Rash, angioedema, urticaria.
• Ihe ngosi ulo oru: anaemia, hyperkalemia.
• Ndị ọzọ: erythemaitching dyspnea.

Mikardis, ntuziaka maka ojiji

Dika ntuziaka maka iji Mikardis, a na-ewere ọgwụ ọnụ. Akwadoro maka ndị okenye kedụ 40 mg otu ugboro n'ụbọchị. N'ọtụtụ ndị ọrịa, a chọpụtalarị ọgwụgwọ ahụ mgbe ị na-a aụ ọgwụ 20 mg kwa ụbọchị. Ọ bụrụ na-egobe nrụgide nke ọkwa nke ịchọrọ, ọ pụtaghị ịrị elu ahụ gaa na 80 mg kwa ụbọchị.

Mmetụta kachasị nke ọgwụ ahụ na-enweta izu ise mgbe ịmalite ọgwụgwọ.

N'ime ndị ọrịa nwere ụdị siri ike ọbara mgbali ike enwere ike iji ya 160 mg ọgwụ kwa ụbọchị.

Dodoụbiga ya ókè

Mgbaàmà: iweda ọbara mgbali elu.

Mmekorita

Telmisartan rụọ ọrụ mmetụta hypotensive ụzọ ndị ọzọ nke iwetulata nrụgide.

Mgbe ejikọtara ọnụ telmisartan na digoxin oge ekwesiri itinye uche n'ihe digoxin n’ime ọbara, dịka o nwere ike ibili.

Mgbe ị na-a drugsụ ọgwụ ọjọọ lithium na Ihe mgbochi ACE enwere ike ịhụgo mgbakwunye na ọdịnaya nwa oge lithium n'ọbara, nke ihe ndia na aru aru.

Ọgwụgwọ ọgwụ mgbochi-anaghị egbochi steroidal ya na Mikardis na ndi oria akpukpo aru nwere ike ibute mmepe nke nnukwu akwara gbasara ha.

Usoro ahia

A na-ahapụ ya kpam kpam dị ka ndenye ọgwụ.

Ọnọdụ nchekwa

Chekwaa na nkwakọ ngwaahịa emechighi, na okpomọkụ ruo 30 Celsius C, na ebe kpọrọ nkụ. Ekwela ka ụmụaka ghara iru ya.

Exbọchị mmebi

Ntụziaka pụrụ iche

N'ihi na ndị ọrịa gwụrụ (mgbochi nnu, ọgwụgwọ diuretics, afọ ọsịsa, vomiting) mbelata nke ọgwụ Mikardis dị mkpa.

Jiri nlezianya na-ahọpụta ndị mmadụ stenosis ha abuo gbasara akwara, mitral valve stenosis ma obu cardioyopathy aortic hypertrophic ihe mgbochi, nnukwu akụrụ, ọrịa ịba ọcha n'anya ma ọ bụ nkụchi obi, ọrịa nke ngwara nri.

Amachibidoro iji ya mgbe isi izizi na fructose anabataghị ya.

Site na ịtụrụ ime, ị ga-ebu ụzọ chọta onye ọzọ maka Mikardis ọgwụ antihypertensive.

Jiri mkpachapụ anya mgbe ị na-anya ụgbọala.

Na concomitant iji ọgwụ ọjọọ lithium A na - egosiputa nlezianya nke ọdịnaya lithium n'ime ọbara, ebe ọ bụ na enwere ike ịbawanye nwa oge na ọkwa ya.

Mikardis analogues

Ihe analogues Mikardis na - esosi: Ochichi, Telmista, Hipotel.

Amachibidoro ọgwụ a maka iji ndị n’agbata afọ 18.

N’ime ime (ma lactation)

Amachibidoro iji ụmụ nwanyị dị ime na ndị na-actụ ara.

Nyocha banyere Mikardis

Nyocha banyere Mikardis bụ obere akụkọ nke mmetụta ndị na-emetụta ya, mana ọtụtụ ndị ọrịa enweghị afọ ojuju maka ọnụ ahịa ya dị elu.

Mikardis Ahịa

Na Russia, ngwugwu nke 80 mg Nke 28 ga-efu site na 830 ruo 980 rubles. Na Ukraine, ọnụahịa Mikardis n'otu mbipụta ahụ na-eru nso hryvnias 411.

• Pharlọ ọgwụ n'ịntanetị dị na Russia
• Aclọ ahịa ọgwụ n'ịntanetị na UkraineUkraine
• Pharmlọ ahịa ọgwụ dị n'ịntanetị na Kazakhstan

• Mikardis Plus mbadamba 80 mg + 12.5 mg 28 pcs Boehringer Ingelheim Böhringer Ingelheim
• Mbadamba Mikardis 80 mg 28 PC.
• Mbadamba Mikardis 40 mg 28 pcs Boehringer Ingelheim Böhringer Ingelheim

• Mikardis 40mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis gbakwunyere 80mg / 12.5mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis 40mg Nke 14 tabletBeringer Ingelheim Pharma GmbH na CoKG
• Mikardis 80mg Nke 28 tabletBeringer Ingelheim Pharma GmbH na CoKG

IFlọ ọgwụ IFK

• MikardisBoehringer Ingelheim, Germany
• Mikardis Plus, Boehringer Ingelheim, Germany

• Mbadamba Mikardis 80mg Nke 28Beringer Ingelheim (Italy)
• Mikardis-gbakwunyere mbadamba 80mg / 12.5mg Nke 28Beringer Ingelheim (Germany)

Pharlọ ọgwụ Pani

• Mikardis tab. 80mg Nke 28Beringer Ingelheim
• Mikardis tab. 80mg Nke 28Beringer Ingelheim

• Mikardis® Plus 80 mg / 12.5 mg Nke 28 mbadamba Boehringer Ingelheim Pharma KG (Germany)
• Mikardis® 80 mg Nke 28 mbadamba Boehringer Ingelheim Pharma KG (Germany)

Kwụsị uche! Ihe omuma banyere ogwu nke saịtị a bu ihe banyere nbuso-agha, anakpo ya site n public isi obodo ma na enweghi ike ibu ihe ndabere iji kpebie etu ogwu si di. Tupu ị Mikụ ọgwụ Mikardis, jide n'aka ịkpọ dọkịta gị.

Ọgwụ "Mikardis": analogues, ntuziaka maka ojiji, nyocha:

Edere Mikardis nye ndị ọrịa ka ha wepu ihe ịrịba ama nke ọbara mgbali elu. Ọgwụ nwere akụ hypotensive, a na-ahọrọ usoro onunu ogwu maka onye ọrịa ọ bụla. Tupu ị takingụ ọgwụ ahụ, a na-atụ aro ka ọ gụọ ntuziaka maka ya, ịmụ ọgwụ mgbochi, yana mmetụta ndị ọzọ.

Ngwakọta nke ọgwụ "Mikardis"

Ihe na-arụ ọrụ, nke bụ isi bụ ihe mepụtara learism, bụ telmisartan. Otu mbadamba nwere ike ịnwe milligrams 20 ruo 80.Ngwa ndị ọzọ na - enyere aka ịbanye ngwa ngwa nke ugbu a bụ:

• yoxitalamic acid
• sodium hydroxide
• polyvinylpyrrolidone,
• glucite
• stereta magnesium.

Oge mbu nke "Mikardis" na-eduga n'itinye nwayọ nke ọbara mgbali elu. O jiri nwayọ belata n’ime ọtụtụ awa. A na-ahụ mmetụta antihypertensive otu ụbọchị mgbe ị takingụsịrị ọgwụ ahụ.

Nke a pụtara na iji nọgide na-enwe ọbara mgbali nkịtị, ọ dị mkpa iji otu mbadamba Mikardis kwa ụbọchị. Enwere ike ịhụ mbelata nke nrụgide kachasị ukwuu mgbe ọnwa gasịrị site na mmalite ọgwụ.

Site na njiri siri ike iwere "Mikardis" ọ nweghị mmetụta nke "kagbuo", ndị na-egosi mbụ na-alaghachi n'ime izu 2-3.

Ihe niile mejupụtara ọgwụ ahụ, mgbe a na -ewere ya ọnụ site na eriri afọ, na-etinye obi gị dum ngwa ngwa, mkpokọta kachasị nke ihe ndị dị n'ọrụ ruru ihe ruru 50%.

Mpempe mwepụta

Mikardis dị na mbadamba ọcha. Ihe ngwugwu nwere ike ịnwe blisters abụọ ruo asatọ, nke ọ bụla nwere mbadamba 7.

Etu esi ewere ogwu a?

N'ọnọdụ ndị a na-adịghị ahụkebe, a na-enye ọgwụ ahụ maka ndị ọrịa karịrị afọ 55, bụ ndị nọ n'ihe ize ndụ nke ịmalite ọrịa obi obi jikọtara ya na ọbara mgbali elu.

Na mgbakwunye na "Mikardis" mbụ, a na-emepụta ọgwụ "Mikardis gbakwunyere". Nke ikpeazụ a nwere milligram 12.5 nke hydrochlorothiazide, nke nwere akụrụngwa diuretic.

Nchikota ọgwụ diuretica na anonistensin antagonist na - enyere aka inweta oke. Diuretic na-amalite ịpụta ka elekere abụọ gachara ọgwụ ọjọọ. Edere "Mikardis gbakwunyere" ma ọ bụrụ na ọ gaghị ekwe omume nweta mbelata nrụgide mgbe ị na-ewere "Mikardis".

N'ọnọdụ ọ bụla ịkwesịrị ị drugụ ọgwụ na usoro onunu ogwu gị, ebe ọ bụ naanị dọkịta na-aga ya kwesịrị ịchọpụta ọgwụ mgbochi niile ma nyocha nyocha nke onye ọrịa.

Ihe ngbanwe

"Mikardis 40" nwere otu ọgwụ ọgwụ dịka ọgwụ nwere ihe dị iche iche na - arụ ọrụ arụ ọrụ. Enweghị ike ị drugụ ọgwụ ahụ n'okwu ndị a:

1. Ọ bụrụ na enwere mmụba na-abawanye na isi ma ọ bụ ihe inyeaka.
2. N'oge ime na lactation.
3. Ọ bụrụ na onye ọrịa nwere nsogbu nke biliary tract, nke nwere ike imetụta akụkụ ha.
4. Na nnukwu ọrịa nke imeju na akụrụ.
5. Na fructose ekweghị ibe nọrọ.

Ntụziaka maka iji "Mikardis" na-egosi na enyeghị ọgwụ ọgwụ ka ndị ọrịa nwee:

• refractory hypercalcemia (ụbara calcium plasma bara ụba),
• hypokalemia (ọrịa na-akpata site na enweghị potassium na ahụ mmadụ),
• na ụkọ lactase,
• lactose anagide ihe,
• galactose anabataghị ya.

Ọgwụ "Mikardis" nwere oke ịkpachapụ anya ka edepụtara maka:

• Hyponatremia (ọnọdụ ọnụnọ sodium ion na plasma ọbara dara n'okpuru nkịtị).
• Hyperkalemia
• Obi ischemia.
• Ọrịa obi - ọdịda na-adịghị ala ala, valvụ stenosis, cardiomyopathy.
• Stenosis nke akwara abụọ nke akụrụ.
• Mmiri na-egbu site na ọrịa na-arịa ọria vom na afọ ọsịsa.
• Usoro ọgwụgwọ diuretic gara aga.
• Iweghachite mgbe akụrụ gbasara ntụgharị.

Ekwesịrị iji nlezianya mee ọgwụ ahụ na ọrịa shuga na gout (ọrịa nke nkwonkwo na anụ ahụ kpatara nsogbu metabolism na ahụ).

Nsonaazụ

Nyocha banyere "Mikardis" anaghị adị mma mgbe niile. Patientsfọdụ ndị ọrịa na-edekọ ihe na-arịa ahụike na-adịghị mma, nke dabere kpọmkwem na usoro ị doụ ọgwụ ahụ, afọ yana ọnụnọ ọrịa. Nsonaazụ kachasị akpata bụ:

• Dizziness, migraine, ike ọgwụgwụ, oke ụjọ, ahụ erughị ala, obi erughị ala, ụra na-egbu m, nsogbu.
• Ọrịa na-efe efe na-efe efe na-ebute ọrịa pharyngitis, sinusitis, bronchitis na ụkwara.
• Nausea, flatulence, afọ ọsịsa.
• Hypotension (ọbara mgbali ala), tachycardia (ọrịa obi na-egbu mgbu), bradycardia (mgbagha sinus).
• Akwara anụ ahụ, arthralgia, mgbu azụ.
• Ọrịa nke usoro mkpụrụ ndụ, njigide mmiri n'ime ahụ.
• Ihe nfụkasị ahụ n'ụdị rashes, urticaria, angioedema, itching, erythema (ọnya na-acha ọbara ọbara nke ukwuu site na mgbasa nke capillaries).
• Oge adịghị anya ọhụụ.
• Mmechi akpukpo nkpuchi.
• Enweghi ike (enweghi ike nwoke na nwanyi).
• Pancreatitis (mbufụt nke pancreas).
• Ọrụ imeju na-arụ ọrụ.
• Jaundice
• Dyspepsia (imebi ọrụ dịịrị afọ, nri mgbaze siri ike na-egbu mgbu).
• Ọsụsọ mụbara.
• Mmeghe n'ime akwara nke nwa ehi.
• Ọrịa ogbu na nkwonkwo (ọrịa nkwonkwo na-adịghị ala ala metụtara nrụrụ ha na njedebe nke agagharị).

Mikardis n'oge di ime

Ọmụmụ ihe omimi nyochaputala mmetụta fetotoxic nke ọgwụ. Ya mere, apughi iburu "Mikardis" na udu onyunyo niile n’oge a na-ete nwa. Ọ bụrụ na nwanyị chọrọ ịbụ nne, ndị dọkịta na-enye ndụmọdụ ka ọ gbanwee ka ọgwụ ndị na-adịghị ize ndụ. Mgbe ime ime, a kwụsịrị ị theụ ọgwụ.

Etu esi ewere ọgwụ "Mikardis"?

Ọ bụ naanị dọkịta ka o nyere ọgwụ ahụ ma ọ nwere ike iji ya rụọ ọrụ onwe ya yana ọgwụ ndị ọzọ maka ebuli ịrụ ọrụ nke sistem obi. Russian Mikardis analogues nwere otu ụdị ọrụ ahụ.

Ntụziaka eji eme ihe na-egosi na ị intụ ọgwụ kwa ụbọchị kwesiri ịdị naanị otu mbadamba 40 milligrams.

Ekwesịrị icheta na n'ime ndị ọrịa nwere ụdị ọbara mgbali elu, mbelata ọbara mgbali na-apụta mgbe ị na-ewere mbadamba nkume nwere milligrams 20 nke ihe na-arụ ọrụ. A na-eme nhọrọ nke usoro ọgwụgwọ ọgwụgwọ oge ruo izu anọ.

N'ezie, ọtụtụ oge dị mkpa maka Mikardis iji gosipụta mmetụta ya niile dị n'ahụ ahụ onye ọrịa.

Ọ bụrụ na n'ime ọnwa iwere "Mikardis 20" nsonaazụ ahụ achọrọ abịaghị, dọkịta depụtara ọgwụ iji ọgwụ ruru 80 milligram, nke dịkwa mkpa ị beụ otu mbadamba ụbọchị.

N'okwu ndị siri ike nke ọrịa ahụ, dọkịta nwere ike ịkọpụta "Mikardis" na usoro nke milligrams 160, ya bụ, ị ga-ewere mbadamba 2 kwa ụbọchị, 80 milligrams.

N’ọnọdụ ndị a na-adịghị ahụkebe, onye na-arịa ọrịa anaghị adalata ọbara mgbali elu dị ka otu ọgwụ, mgbe ahụ ka edepụtara onye ọrịa dị otú ahụ "Mikardis gbakwunyere", n'ihi nke mgbali ahụ na-ebelata ngwa ngwa. Usoro nke ị drugụ ọgwụ ahụ n'ọnọdụ a ka ahọrọ site na mmepe nke ọbara mgbali elu. Nyocha banyere "Mikardis" na analogues gosipụtara mmetụta dị mma ya na iwetulata ọbara mgbali elu.

Ndị ọrịa nwere akụkọ gbasara ahụike ya na-arụ ọrụ anaghị achọ nhọpụta usoro ọgwụgwọ nke otu onye.

Ọ bụrụ na ozi a nwere ndekọ banyere ọghọm ọnya ọgbụgba nke ọrịa imeju, mgbe ahụ onye ọrịa ga-ewererịrị "Mikardis 40".

Nweghị ike ịba ụba dose ọgwụ a: nke a nwere ike ibute arụ ọrụ akụrụ na imeju. Ndị ọrịa merela agadi adịghị edozi usoro ọgwụgwọ ahụ.

N'ime ndị ọrịa nwere mellitus ọrịa shuga, yana ọrịa obi na akwara obi ma ọ bụ ọrịa obi ndị ọzọ, ohere nke infarction myocardial na-egbu egbu na ọnwụ mberede na-abawanye n'ihi iji ọgwụ Mikardis.

Ọrịa obi obi na-arịa ọrịa shuga mellitus nwere ike ime n'enweghị ihe mgbaàmà ma enweghị ike ịchọpụta ya na mbido. Ya mere, tupu ịmalite ọgwụgwọ na ọgwụ Mikardis, ị ga-agabiga ule niile dị mkpa ma gaa nyocha.

Mmekọrịta na ọgwụ ndị ọzọ

Tupu dọkịta nyefee Mikardis onye ọrịa ahụ, ọ ga-achọpụta ọgwụ ndị ọzọ onye ọrịa ahụ na-a .ụ. Mgbe ị na-a medicinesụ ọgwụ ndị a, mmetụta ha nwere ike ịba ụba, ma ọ bụ mmetụta nke "Mikardis":

1. Telmisartan na-abawanye mmetụta hypotensive nke ọgwụ ndị ọzọ nwere mmetụta yiri ya.
2. Na njikọta ọgwụ na Digoxin na Mikardis, ntinye uche nke ihe na-arụ ọrụ n'ime ọgwụ mbụ na-abawanye.
3. Ntinye uche nke "Ramipril" na-abawanye ugboro abụọ.
4. Ọgwụ nke ọgwụ lithium na-abawanye, nke a na - eme ka ahụ ndị mmadụ nwee nsị na -eme arụ ahụ.
5. Site na iji ọgwụ mgbochi mkpali na steroidal na-abụghị steroidal na telmisartan na ndị ọrịa nwere akpịrị ịkpọ nkụ, ihe ọghọm nke ịmalite imebi akụrụ na-abawanye na mmetụta Mikardis na-ebelata.

Ike ijikwa usoro mgbagwoju anya mgbe ị na-ewere "Mikardis gbakwunyere" na analogues

Ntụziaka maka ojiji na-egosi na emebeghị nnyocha pụrụ iche etu esi arụ ọrụ (telmisartan), nke bụ akụkụ nke ọgwụ na ọtụtụ analogues, na-emetụta ntinye uche na ike ịkwọ ụgbọala. Mana! Ekwesịrị icheta na ọgwụ nwere ihe ndị mejupụtara diure nwere ike ibute iro ụra na nkụ.

Ọgwụ a "Mikardis" ga-echekwara ya ebe ụmụaka agaghị enweta ya, na-enweghị ogo 30. Ndụ shelf:

1. Mbadamba ụrọ nwere ogwu nke 40 na 80 milligrams - afọ 4.
2. Mbadamba nwere usoro ogwu nke 20 milligrams - afọ 3.

A na-enye ọgwụ ọgwụ ike dabere na ndenye ọgwụ ahụ. Amachibidoro "Mikardis" maka ụmụaka na-erubeghị afọ 18.

Ọnụ ego ọgwụ ahụ "Mikardis"

Ọnụ ahịa ọgwụ na-adabere na usoro onodu ogwu ahụ si arụ ọrụ. Ọnụ ego nke "Mikardis 40" (mbadamba 14) - site na 500 rubles na karịa. "Mikardis 80" - site na 900 ruo 1000 rubles. Ọnụahịa Mikardis Plus (mbadamba 28) sitere na 850 rubles na karịa.

Mikardis: analogues, nyocha

Ntụziaka maka iji ya kwuo na ị nwere ike ị theụ ọgwụ ahụ n’oge ọ bụla n’ụbọchị, iri nri anaghị emetụta ikike ahụ mmadụ iji nweta ọgwụ ahụ.

Oge ngụkọta ọgwụgwọ ahụ dabere na dọkịta, mgbe ọ tụlechara ahụike onye ọrịa, dọkịta ahụ nwere ike ịkwado ịtụgharị ka ọ dị miligram abụọ.

Ndị na-a theụ ọgwụ ahụ na-achọpụta mbelata ọbara mgbali ngwa ngwa na enweghị ọghọm ya. Mana ọnụ ọgụgụ ka ukwuu nke ndị ọrịa ịzụta ọgwụ a bụ ọnụ ahịa dị elu na-akwụsị ya.

Dọkịta ahọpụtara ụdị analogues ndị dị ọnụ ala karịa "Mikardis gbakwunyere", ọgwụ ndị ama ama nwere mmetụta yiri ya gụnyere:

Pricegwọ nke analogues nke ọgwụ Mikardis dabere na mba mepụtara yana ihe mejupụtara ọgwụ ahụ. Na ego dị ala, ị nwere ike ịzụta ihe analogues ndị a:

1. Blocktran bụ ọnụọgụ dị ọnụ ala ma na-akwụkwa ụgwọ maka ọgwụgwọ ọbara mgbali elu na nkụchi obi na-adịghị ala ala. Ọ dị iche na Mikardis na akụrụngwa na usoro onunu ogwu.
2. A na - emepụta “Valz” - ngwugwu nke mbadamba 28, nke karịrị nnọọ ọgwụ “Mikardis”, yabụ, na ọgwụgwọ ogologo oge, “Valz” dị ọnụ ala. Nhazi nke ọgwụ dị iche iche, ebe ọ bụ na a na-eji Valsartan (40 milligrams) na Valz.
3. "Angiakand" - dị iche na mejupụtara, ihe na-arụ ọrụ na-arụ ọrụ na usoro ya. A na-ahapụ ya ka ọ were ọbara mgbali elu na obi daa ọrịa. Ọ nwere contraindications ndị ọzọ, yabụ na-atụ aro ka ị jiri nlezianya gụọ ntuziaka tupu ojiji.

Mikardis Plus: ntuziaka maka ojiji, analogues

Ọgwụ "Mikardis gbakwunyere" bụ maka ọgwụgwọ nke ọrịa obi na iji belata onwu. E gosipụtara ya maka ọrịa myocardial n'etiti ndị gbara afọ 55-60. A kọwara ọgwụ a kọwara na Germany. Tupu ojiji, ịchọrọ ndụmọdụ dọkịta, nyocha zuru ezu nke data banyere akụrụngwa na njirimara, nke nwere ntuziaka maka iji ọgwụ Mikardis.

Ndị na-ahụ maka ọgwụ

Ọgwụ a dịịrị otu ndị na-emegide ihe metụtara angiotensin, ya bụ, ndị otu ọgwụ na-eme ihe na ndị na-anabata ndị ọrụ AT ma kegide ọbara maka mmetụta ka mma. Protohypertensive, ọgwụ na-ebelata nrụgide. O nweghi ogwugwo na ogwu mgbochi.

Ngwakọta, usoro nke ime ihe na ụdị ntọhapụ

Ọgwụ dị n'ụdị mbadamba ọcha nke whitish nwere njiri mara ụlọ ọrụ n'otu akụkụ, na nke abụọ - ya na “51N” ma ọ bụ “52N”, dabere na usoro onunu ogwu. N'ime ngwugwu kaadiboodu, ọgwụ nwere ike ịnwe efere 2 ruo 8 nwere mbadamba 7 n’ime nke ọ bụla. Ngwakọta nke otu mbadamba "Mikardis" gụnyere ihe ndị egosipụtara na tebụl ha.

Nkọwa nke metụtara 21.08.2014

• Aha Latin: Micardis
• Koodu ATX: C09CA07
• Arụ Ọrụ: Telmisartan (Telmisartan)
• Emeputa: BOEHRINGER INGELHEIM PHARMA (Germany)

Otu mbadamba Micardis nwere 40 mg ma ọ bụ 80 mg telmisartan (ike ihe).

Ndị e mere: sodium hydroxide, polyvidone, meglumine, sorbitol, magnesium stearate.

Mpempe mwepụta

Ọgwụ bụ mbadamba ihe na-acha ọcha na-acha uhie uhie nwere ihe osise 51H nke dị n'otu akụkụ na akara ụlọ ọrụ dị na nsọtụ ọzọ.

7 ụdị mbadamba ụrọ nke nwere 40 mg na paịlị; 2 ma ọ bụ 4 na blisters dị na igbe kaadi. Edide 7 dị mbadamba ụrọ dị otú a na-a ofụ ọgwụ dị 80 mg na chara acha, 2, 4 ma ọ bụ 8 na blisters dị otú ahụ na igbe kaadi.

Omume ọgwụ

Mgbachi angiotensin II n'ihi ya, vasodilation. Ọgwụ ahụ na-ebelata ọbara mgbali elu, afọ ojuju aldosterone n’ime ọbara.

Pharmacodynamics na pharmacokinetics

Mlọ ọgwụ

Telmisartan - ihe na - ahọrọ ihe nnabata angiotensin II. Nwere nnukwu ebe ije dị AT1 ụdị nnabata angiotensin II. Asọmpi na angiotensin II na ndị nnabata kpọmkwem na-enweghị otu mmetụta. Njikọ ahụ na-aga n'ihu.

O gosiputaghi ikpo oku maka ihe ndi ozo nke nabata ya. Na-ebelata ọdịnaya aldosterone n'ọbara, anaghị egbochi plasma renin na ọwa ion n’ime sel.

Bido mmetụta hypotensive A hụrụ n'ime elekere atọ izizi mgbe nchịkwa gasịrị telmisartan. Omume ahụ dịgide otu ụbọchị ma ọ bụ karịa. Nkwupụta akpọrọ ahụ na-etolite otu ọnwa mgbe nchịkwa na-aga n'ihu.

N'ime ndị mmadụ na- ọbara mgbali iketelmisartan na-ebelata systolic na ọbara mgbali ọbara, mana anaghị agbanwe ọnụọgụ nke obi obi.

Ọ naghị akpata ọrịa wepụ ego.

Mlọ ọgwụ

Mgbe a na -ewere ya okwu ọnụ, ọ na-abanye na eriri afọ ngwa ngwa. Bioavailability na-erute 50%. Mgbe awa atọ gachara, plasma ịta ga-akachasị. 99.5% nke ihe arụ ọrụ na-egbochi protein protein. Metabolized site na nzaghachi na acid glucuronic. Metabolites nke ọgwụ ahụ anaghị arụ ọrụ. Iwepu ọkara ndụ dị ihe karịrị awa iri abụọ. A na-ewepụta ya site na ngwara, digesion na mmamiri erughị 2%.

Ihe ngosi maka ojiji

• Ọbara ọbara.
• Mbelata ọrịa obi na ọrịa na-egbu ndị mmadụ karịa afọ iri ise na ise nọ n'ihe ize ndụ.

Ihe ngbanwe

Mpempe akwụkwọ Micardis na-egbochi ndị mmadụ iche iche allergies n'ihe ndị dị na ọgwụ ahụ, dị arọ ọrịaimeju ma obu akụrụ, fructose anabataghị ya, n'oge ime na lactation, ụmụaka ndị gbara afọ 18.

Nsonaazụ

• Site na usoro ụjọ ahụ: ịda mbaanya ntughari isi ọwụwaike ọgwụgwụ, nchekasị, ehighi ura, ogwe.
• Site na usoro iku ume: ọrịa nke akụkụ okuku ume na elu (sinusitis, pharyngitis, ọla kọpa), ụkwara.
• Site na sistemụ mgbasa: ekwuputala mbelata nke nrụgide, tachycardia, bradycardiaobi mgbu.
• Site na usoro digestive: ọgbụgbọ, afọ ọsịsa, dyspepsiaịba ụba ịta nke enzymes imeju.
• Site na usoro mọzụlụ: myalgiaobere azụ mgbu arthralgia.
• Site na usoro genitourinary: edema, ọrịa nke usoro genitourinary, hypercreatininemia.
• Mmeghachi omume Hypersensitivity: Skin Rash, angioedema, urticaria.
• Ihe ngosi ulo oru: anaemia, hyperkalemia.
• Ndị ọzọ: erythemaitching dyspnea.

Mikardis, ntuziaka maka ojiji

Dika ntuziaka maka iji Mikardis, a na-ewere ọgwụ ọnụ. Akwadoro maka ndị okenye kedụ 40 mg otu ugboro n'ụbọchị. N'ọtụtụ ndị ọrịa, a chọpụtalarị ọgwụgwọ ahụ mgbe ị na-a aụ ọgwụ 20 mg kwa ụbọchị. Ọ bụrụ na-egobe nrụgide nke ọkwa nke ịchọrọ, ọ pụtaghị ịrị elu ahụ gaa na 80 mg kwa ụbọchị.

Mmetụta kachasị nke ọgwụ ahụ na-enweta izu ise mgbe ịmalite ọgwụgwọ.

N'ime ndị ọrịa nwere ụdị siri ike ọbara mgbali ike enwere ike iji ya 160 mg ọgwụ kwa ụbọchị.

Dodoụbiga ya ókè

Mgbaàmà: iweda ọbara mgbali elu.