Mbadamba Acekardol - ihe mejupụtara na akara, usoro nke ime ihe na contraindications, analogues na ọnụahịa

Ọgwụ "Acecardol" bụ acetylsalicylic acid, nke a gbanyere mkpọrọgwụ, nke na-agbaze na eriri afọ. Ọ bụ ọgwụ na - abụghị steroidal nwere mmetụta mgbochi mkpali. Acetylsalicylic acid dị na usoro onyonyo dị iche iche na analogues niile Acecardol.

O nwere ikike igbochi njikọ nke thromboxane ma gbochie usoro ijikọta platelet n'ime mkpo. A na-ahụta mmetụta a nke Acecardol ọbụlagodi na obere usoro eji ya ma ọ ga-adịgide na-eji otu izu. Na nnukwu usoro, ọgwụ ahụ nwere ọgwụ antipyretic, analgesic na anti-inflammatory.

Otu mbadamba 1 nwere 50, 100 ma ọ bụ 300 mg nke acetylsalicylic acid na-arụ ọrụ. Ọgwụ a bụ nke ndị ụlọ ọgwụ NSAIDs, nke na-ahụ maka ọgwụ na ọgwụ.

Ndabere nke usoro ihe eji eme ihe bu ihe nwere ike igbochi cyclooxygenase site na akụrụngwa na-arụ ọrụ, nke na-eme ka mgbochi nke mmepụta thromboxane A2 na mbelata agụkọta platelet. Mmetụta antiplatelet ahụ riri site na otu mbadamba ihe ruru otu izu.

Ihe ngosi maka iji Acecardol

Acecardol na - egbochi thrombosis, na - egbochi mmepe na ọganihu nke nkụchi obi, ọrịa ọnya afọ, na thromboembolism. Ogologo oge iji nke kaadicardol na-abawanye oge na ogo ndu ndi ọrịa. Ndị ọrịa nwere nkụda mmụọ oge nwetagoro mmụba n'ọnọdụ ha, ọdịmma ha n'ozuzu ya na nrụgide nke ịdị nkịtị.

Edere Acecardol maka angina pectoris na-ejighi ike, iji gbochie nsogbu infarction ugboro ugboro, iji gbochie ọrịa mamịrị (ya na ngalaba ya) yana mkpụrụ ndụ akwara dị ala (na-anaghị adịte aka, dịka ọmụmaatụ, n'oge ịwa ahụ ogologo oge).

Ntụziaka maka iji usoro Acecardol

Gwa dọkịta gị banyere ọgwụ kachasị mma maka gị kwa ụbọchị. A na - akwado ọgwụ Acetylsalicylic acid nke 50-150 mg kwa ụbọchị maka iji ogologo oge. Dịka iwu, edere ha ka ha bie ndụ ma ọ bụrụ na enweghị mmetụta ọjọọ ọ bụla.

E nwere nkezi usoro ịagesụ ọgwụ ọ usedụ usedụ eji na mgbochi nke ọrịa dị iche iche. Iji gbochie nnukwu ọrịa myocardial infarction, na-enweghị na ọnụnọ nke ihe ọghọm, thromboembolism nke akwara umeji yana alaka ya ka a na-agbanye ọgwụ nke vein thrombosis nke 100 mg kwa ụbọchị ma ọ bụ 300 mg kwa ụbọchị nke abụọ (ọ bụ ihe dị mma ịta ata nke mbụ maka nnabata ngwa ngwa).

Njirimara ngwa

Ka ị na-a Aceụ ọgwụ Acekardol, akpachara anya kwesịrị igosipụta mgbe ị na-anya ụgbọala, usoro na mgbe ị na-eme ihe ndị ọzọ nwere ike ịdị ize ndụ nke chọrọ mmụba nke uche na ọsọ nke mmeghachi omume psychomotor.

N'oge usoro ọgwụgwọ yana nkwadebe dabere na acetylsalicylic acid, a ga-enyocha ule ọbara kwa oge, ebe ihe a na - enye aka na ịmịcha ọbara ya. Site na iji kaadi kaadi ogologo oge na enweghị nchịkwa, ihe ọghọm nke ịmalite ọbara ọgbụgba n'ime ahụ dị oke.

Mgbe a takenụrụ mmanya n’otu oge, mmetụta mmanya na-egbu egbu na-abawanye, ohere nke ọbara na-abawanye ma oge ha na-abawanye, ihe ọghọm nke imebi akpụkpọ ahụ eriri afọ na-abawanye.

Acecardol nwere mmetụta ọgwụ ọjọọ dịka:

- methotrexate,
- heparin,
- insulin
- cardyac glycosides.

Acekardol - kedu ọgwụ ndị a si

Ndị dọkịta depụtara mbadamba Acekardol maka ebumnuche mgbochi, mgbe a wasịrị ya ahụ na akwara obi ma ọ bụ iji zere ihe ize ndụ nke ọrịa strok nke abụọ na ndị ọrịa nwere ọrịa ọhụụ. Mmetụta ahụ erughị ala na ihe mgbu na mpaghara obi (angina pectoris) na-arụkwa ọrụ dị ka ihe kpatara ịmalite ịmalite Acecardol dị ka akụkụ dị mkpa nke usoro ọgwụgwọ siri ike.

Dabere na ntuziaka maka ojiji, Acekardol bụ otu nke ọgwụ antiplatelet. Ebumnuche ya bụ igbochi ngwụsị nke paịlị na mkpụrụ ndụ ọbara uhie. Nsonaazụ nke ọgwụ Acekardol na usoro nke hematopoiesis bụ iji mee ka ikike ichepu mmadụ nke ọma pụta, ihe ọgbụgba nke mkpụkọ ọbara, nke etoliteworo n'ihi ihe ịtụnanya na - eme na obi na akwara ọbara.

Akụrụngwa nọ n'ọrụ na-etolite ntọala maka ihe mejupụtara ọgwụ Acecardol bụ acetylsalicylic acid, nke amaara maka oke ọgwụgwọ ọgwụgwọ ya. A na-eji ihe ndị a na -eme ka akụrụngwa inyeaka na ntanetị ruru

• polyvinylpyrrolidone pere mpe pere mpe - 1.8%,
• stachi ọka - 9,5%,
• microcrystalline ntụ ntụ nke polysaccharide osisi (cellulose) - 5.6%,
• stearic acid (ma ọ bụ magnesium stearate) - 0.6%,
• talc - 1.7%
• mmiri ara ehi glucose monohydrate (lactose) - 53%.

Mpempe mwepụta

Ọnọdụ ọgwụ Acecardol, nke eji gosipụta ihe ọgwụgwọ ya n'ụzọ zuru oke, bụ mbadamba nkume nwere shei ọcha na-eguzogide acid nwere ọdịnaya nwere 50, 100 ma ọ bụ 300 mg. Ihe mejupụtara ya bụ nke na-enye akụrụngwa na-egbu egbu na oghere ahụ (ọgwụ mkpuchi):

• cellulose acetate - na-egbochi mgbasa na esophagus,
• titanium dioxide - na - egbochi uto hydrochloric acid,
• Castor mmanụ (ricinoleic acid) - na-eme ka ọ dị mma ma na-emekwa ka mbadamba ụrọ sie ike.

Pharmacodynamics na pharmacokinetics

Usoro nke ihe mgbochi antiplatelet Acekardol, dị ka ntuziaka maka ojiji si dị, na-egbochi igbochi thromboxanes na akụkụ nke mkpụrụ nke cyclooxygenase. Usoro mgbochi ahụ na - enyere aka ịkwụsị njikọ nke prostanoids na ikpokọta nchịkọta platelet, n'ihi nke a rụpụtara ihe antipyretic, mbelata ihe mgbu na mkpochapu ihe mgbaàmà mkpali.

Ọgwụ Acekardol, na-abanye na eriri afọ mgbe nchịkwa ọnụ gasịrị, tụfuo mkpuchi na-egbochi acid, na Acetylsalicylic acid nke ewepụtara ga-amalite ịbanye na akụkụ ahụ nke obere eriri afọ. Abalị atọ agachachara Acecardol, ị ga-enweta mkpo kachasị nke ihe dị na plasma ọbara. Mwepu ọgwụ a na - eme site na tubular renal secretion (60% n'ụdị agbanweghị, 40% n'ụdị metabolites).

Acekardol - ngosipụta maka ojiji

Edere ọgwụ antiplatelet maka igbochi egbochi mkpụkọ ọbara na maka ọgwụgwọ nke nsogbu ọbara. Acecardol, dị ka ntuziaka ndị ahụ si dị, ka egosiri maka iji gbochie mmepe nke ọrịa ndị a:

• postolowo thromboembolism (mgbe ọ gbasasịrị, akwara angioplasty),
• obi mgbawa nke akwara obi (isi ihe na-egosi bu angina)
• ọrịa strok
• infarction myocardial (ọ bụrụ na enwere ihe na-ebute ihe egwu dị ka ọrịa mellitus, oke ibu, ịka nká, wdg),
• Ọkpụkpụ ọbara na akwara dị omimi.

Ihe ngbanwe

N'ihi ọnụnọ ulcerogenic acetylsalicylic acid na ihe mejupụtara Acecardol, a na-egbochi ọgwụ a na ụmụaka n'okpuru afọ 18 yana ndị ọrịa ahụ nwere ọrịa ndị ae dere na akụkọ ihe mere eme nke ọrịa:

• ọrịa akụrụ ma ọ bụ ọrịa imeju.
• ọbara ọgbụgba bara ụba
• ọbara ọgbụgba n'ime eriri afọ,
• ụkwara ume ọkụ gụnyere ụkwara ọwara imu ya.
• ihe na-egbu egbu na mucosa gastric.

Usoro onunu ogwu na nhazi

Ntụziaka maka iji ya nwere usoro zuru oke maka iwere ụdị mbadamba Ace Aceol. Ceedgabiga usoro ego egosiputara ma gbanwee usoro iji ọgwụ a akwadoghị na-enweghị nkwenye dọkịta. Ọgwụ ga-abanye na eriri afọ ya na-emerụ enweghị ntụkwasị obi nke akpụkpọ ahụ, maka nke a, a ga-elo ya kpamkpam wee jiri mmiri washedụchaa mmiri. Ekwesiri ibu Acecardol tupu nri. Iji gbochie mmetụta ọjọọ na mucosa, enwere ike iji mmiri alkaline ịnweta mineral.

Mgbe ị na-ewere Acecardol maka igbochi ọrịa, a ga-agbaso ntuziaka ndị a:

Nsonaazụ na contraindications Acekardol

Dabere na nyocha na nkọwapụta gọọmentị, Acecardol nwere ike bute mmetụta dị iche iche.

• Site na usoro nri: ọgbụgbọ, nkụchi, vomiting, mgbu nke epigastric, ọnya nke mucous akpụkpọ nke afọ na duodenum, ọnya afọ nke afọ na duodenum, ọbara ọgbụgba, ọgbụgba akwara na-adịte aka na ụba ọrụ hepatic transaminases.
• Site na sistemu na-agba ume: nhọpụta nke ASA na-ebute oke ohere ọbara ọgbụgba n'ihi nsonaazụ mgbochi nke ASA na nchịkọta platelet, anaemia.
• Mmeghachi omume nfụkasị: ọnya anụ ahụ, itching, urticaria, edere nke Quincke, rhinitis, ọria nke imi imi, ọrịa obi, yana mmeghachi omume siri ike, gụnyere ụjọ anafilactic.
• Site na sistem iku ume: akwara ozi.
• Site n'akụkụ nke sistemụ akwara: nkụda mmụọ, adịghị ike, ịnụ ntị, isi ọwụwa, tinnitus.

Site na nsonaazụ ndị ọzọ, ọbara ọgbụgba mgbe ị na -eche ezé gị, imi ndị ọzọ na-ebute nsogbu nke oke ọbara ọgbụgba. Ọtụtụ ndị ọrịa na-eme mkpesa banyere obi mgbawa mgbe ha nwusịrị Acecardol.

Ọ bụrụgodị na ị na-enwe mmetụta banyere mmetụta ndị ọzọ, ịkwesighi ịkwụsị n'enweghị nsogbu ọ bụla iji Acekardol. Gwa dọkịta gị ma ọ bụrụ na ị nwere ike ịhapụ acetylsalicylic acid ma ọ bụ jiri ihe ọzọ dochie ya. Akwụkwọ akụkọ ahụike na mba ọzọ na-adọ aka na ntị na oge izizi ka ekpochapu ọgwụ aspirin kwa ụbọchị na ndị ọrịa, mkpụkọ ọbara, nkụchi obi na ọnya ọgbụgbọ na-abụkarị n'ihi “nkwụghachi azụ”.

Dodoụbiga ya ókè

Ihe mgbaàmà nke oke ịba oke nke oke nju: ọgbụgbọ, ọgbụgbọ, tinnitus, ịnụ ntị, ọgbụgba, ọgba aghara ihu, ọgba aghara.

Ọgwụ: Mbelata dose.

Nnukwu ịba ụba nke Acecardol na-eyi ọrịa edema, njide obi, oke akụrụ akwara, hyperglycemia na hypoglycemia. Ọ bụrụ na ị overụbiga oke ókè, enwere nnukwu ihe ọghọm nke mmepe ngwa ngwa nke afọ na-agba afọ na eriri afọ.

N'ihe banyere oke mmachi dị ukwuu, a na-eme usoro ndị a: ụlọ ọgwụ ozugbo na ngalaba ndị pụrụ iche maka ọgwụgwọ mberede - lavage gastric, mkpebi nke acid-base balance, alkaline na mmanu alkaline diuresis, hemodialysis, nchịkwa nke ihe ngwọta, unyi na-arụ ọrụ, unyi ọgwụgwọ.

Contraindications:

• eriri afọ,
• ọnya afọ, eriri afọ,
• akwara ụkwara ume ọkụ na ogbo nke iwe na mgbaghara,
• hemorrhagic diathesis,
• ọrịa obi na-adịghị ala ala
• ụmụaka gbara afọ 18,
• polyposis nke paranasal sinuses na imi.

Amachibidoro ya ị theụ ọgwụ Acekardol, analogues na usoro ndị yiri ya n'oge ọmụmụ (dum afọ ime) na inye nwa ara. Ọzọkwa contraindication nwere ike na-atụle onye uche na acetylsalicylic acid na inyeaka ngwa mejupụtara nke ọgwụ, akpan akpan lactose.

Contraindicated na nnukwu akụrụ odida (mwepu creatinine (CC) erughị 30 ml / min). N'iji nlezianya ma ọ bụ naanị n'okpuru nlekọta nke ọkachamara, a na-enye ọgwụ maka ọrụ ezumike mkpọnwụ (CC karịa 30 ml / min).

Anaakọọ Acecardol, ndepụta

Analogs nke Acecardol bụ ọgwụ (ndepụta):

Ihe dị mkpa - ntuziaka maka ojiji nke Acecardol, ọnụahịa na nyocha anaghị emetụta analogues ma enweghị ike iji ya dịka nduzi maka iji ọgwụ eji eme ihe ma ọ bụ mmetụta yiri ya. Oge ọ bụla dọkịta ga-eme ọgwụgwọ, kwesịrị inwe dọkịta. Mgbe ị na-eji dochie Acecardol na analog, ọ dị mkpa iji nweta ndụmọdụ ọkachamara, ị nwere ike ịgbanwe usoro ọgwụgwọ, usoro ịagesụ ọgwụ, wdg Emekwala ọgwụ onwe gị!

Nyocha ndị dọkịta kwuru gbasara ọgwụ Acekardol dị mma. Ndị dọkịta na-ekwu na ọgwụ ọgwụ dị mma maka igbochi obi ọgụ ugboro ugboro, ọrịa strok, yana ọbara ọgbụgba mgbe a wachara ya arụ ma rụọ ọrụ dị mma n'ọrụ ha.

Ndị ọrịa a gwaburu ụdị ọgwụgwọ na-ekwu na ọ bụrụ na i nweghị ire mbadamba ụrọ ahụ, na ahụ agaghị enwe ahụ erughị ala n’afọ mgbe iwechara ya. Nke a na - enye ọgwụ ọjọọ ụdị ọgwụ ahụ. Isi ihe bụ naanị ịgbaso ọgwụ dọkịta gị tụrụ aro ya. Ọzọkwa, ndị ọrịa kwupụtara eziokwu banyere ịdị mma dị na mgbochi na ọgwụgwọ nke egbochi mkpụkọ ọbara.