Etu esi eji Metglib?

Ihe niile gbasara ọrịa shuga »Etu esi eji Metglib Force?

Metglib Force na-ezo aka na ndị ọrụ hypoglycemic. Na-akwalite nhazi ihe ọsọ ọsọ nke ọkwa glucose ọbara. Ọ nwere mmetụta na-adịgide adịgide. A na-eji ụdị ọgwụgwọ shuga 2 mee ihe.

Weputara udi ya na ihe mebere ya

Ọgwụ dị n'ụdị mbadamba ụrọ n'otu usoro nke 2,5 mg + 500 mg na 5 mg + 500 mg. Ihe ndị mejupụtara bụ glibenclamide na metformin hydrochloride. A na-ewepụta ihe ndị ọzọ fọdụrụnụ: stachi, calcium dihydrate, yana macrogol na povidone, obere sel nke cellulose.

Ihe onyonyo nke nkpuru ọcha na-acha ọcha 5 mg + 500 mg ka nke Opadra ọcha, giprolose, talc, dioxide titanium. Mbadamba nwere akara nkewa.

Mbadamba ụrọ 2.5 mg + 500 mg nke okpu, kpuchie ya na mkpuchi ihe nkiri nwere agba aja aja.

Omume ọgwụ

Ọ bụ ihe nnọchianya hypoglycemic jikọtara ọnụ, ihe na-amalite na usoro nke usoro ọmụmụ 2, nke e bu n'uche maka nchịkwa ọnụ. Ọ nwere ma ọpịọkụ ya na extrapancreatic.

Glibenclamide na-akwalite mmiri ọgwụ insulin ka mma site na ibelata nghọta ya site na mkpụrụ ndụ beta na pancreas. N'ihi mmụba insulin ya na-abawanye, ọ na-ejikọ ịgbado sel ngwa ngwa. Usoro nke lipolysis nke adipose anụ ahụ na-akwụsịlata.

A na-enweta ọkwa Plasma kachasị elu mgbe awa 2 gachara ọgwụ a. Ọkara ndụ nke glibenclamide dị ogologo oge karịa nke metformin (ihe dịka awa 24).

Ihe ngosi maka ojiji

Ihe ngosi maka ojiji bu ihe nlebara anya nke ulo ogwu:

• oria oria abuo n’ime ndi okenye, ma oburu na nri na mmega ahu adighi enyere gi aka.
• enweghị ezigbo ọgwụgwọ na njeri sulfonylurea na metformin,
• iji dochie monotherapy na ọgwụ 2 n'ime ndị nwere njikwa glycemic dị mma.

A na-eji ọgwụ ahụ eme ihe maka ụdị shuga 2 n'ime ndị okenye, ma ọ bụrụ na nri na mmega ahụ anaghị enyere aka.

Ihe ngbanwe

E nwere ọtụtụ ọgwụ mgbochi iji ọgwụ a akọwara na ntuziaka. Themfọdụ n’ime ha bụ:

• hypersensitivity nke mmiri ọgwụ,
• ụdị shuga 1
• arụ ọrụ akụrụ
• ọrịa mamịrị ketoacidosis,
• nnukwu ọnọdụ tinyere hypoxia anụ ahụ,
• ime na lactation
• ọrịa na-efe efe
• mmerụ ahụ na arụmọrụ buru ibu,
• ojiji nke miconazole,
• mmanya na-egbu egbu,
• lactic acidosis,
• jidesie ike na nri kalori,
• ụmụaka na-erubeghị afọ 18.

N'inwe nlekọta dị ukwuu, a na-enye ọgwụ a maka ndị mmadụ na-arịa ọrịa febrile syndrome, ahoụrụma, ọrụ isi ike, pituitary gland na thyroid gland. Edebere ya nke ọma nye ndị gbara afọ 45 na karịa (n'ihi oke ịba ụba nke hypoglycemia na lactic acidosis).

Etu esi ewere Metglib Force?

Mbadamba ndị ahụ bụ naanị iji ọnụ. A na-ahọrọ usoro ọgwụgwọ ahụ n'otu n'otu, na-eburu n'uche ogo ịdị njọ nke ngosipụta ụlọ ọgwụ.

Bido na mbadamba 1 kwa ụbọchị jiri usoro nke ihe arụ ọrụ nke 2.5 mg na 500 mg, n'otu n'otu. Jiri nwayọ welite dose ahụ kwa izu, mana nyere ogo nke glycemia. Site na usoro ọgwụgwọ nkwonkwo nnọchi, karịsịa ma ọ bụrụ na a na-ebu ya iche site na metformin na glibenclamide, a na-atụ aro ị drinkụ mbadamba 2 kwa ụbọchị. Oke kacha anabata kwa ụbọchị ekwesịghị ịfefe mbadamba 4 kwa ụbọchị.

Nsonaazụ

N'oge ọgwụgwọ, mmepe nke mmeghachi omume ọjọọ ndị a ga - ekwe omume:

• leuko- na thrombocytopenia,
• anaemia
• nsogbu anaphylactic,
• hypoglycemia,
• lactic acidosis,
• mgbada nke vitamin B12,
• uto mebiri
• ọhụhụ ọhụhụ
• ọgbụgbọ
• vomiting
• afọ ọsịsa
• enweghị agụụ
• mmetụta nke ịdị arọ na afọ
• ọrụ imeju na-arụ ọrụ,
• ịba ọcha n'anya
• akpụkpọ mmeghachi omume
• urticaria
• ihe ndagwurugwu tinyere itching
• erythema
• ọrịa akpịrị
• mmụba na mkpokọta urea na creatinine n'ime ọbara.

Ekwesịrị ịgwa ndị mmadụ banyere ihe ize ndụ hypoglycemia ma mee ihe iji gbochie ya tupu ịbanye n'azụ ụgbọala ma ọ bụ ịmalite ịrụ ọrụ dị mgbagwoju anya nke chọrọ itinye uche nke nlebara anya.

Ntụziaka pụrụ iche

A na-akagbu ọgwụ ahụ na ọgwụgwọ nke oke oku, ọrịa na-efe efe, ọgwụgwọ siri ike tupu ịwa ahụ. N'ụdị ndị ahụ, ha na-agbanye insulin. Ihe ọghọm nke ịbawanye hypoglycemia na-abawanye site na nsogbu ndị dị na nri, ibu ọnụ ogologo oge na NSAIDs.

Anabataghị. Ihe dị ike na-agafe ihe mgbochi site na Plasenta ma nwee ike imetụta usoro nhazi nke akụkụ ahụ.

Can nweghị ike ịillsụ ọgwụ n’oge a na-enye nwa ara, n’ihi bekee na-arụ ọrụ na-abanye n'ime mmiri ara ara. Ọ bụrụ n’ịchọ ọgwụgwọ, ọ ka mma ịhapụ inye ara.

Anaghị etinye ya na ọgwụ ụmụaka.

Menmụ nwoke na ụmụ nwanyị karịrị afọ 65 kwesịrị ịkpachara anya, dịka n’ebe ndị dị otú ahụ nọ, ihe ize ndụ nke ibute ọrịa hypoglycemia mụbara nke ukwuu.

Enwere ike iji ya mee ihe site na mkpochapụ nke creatinine. Ka ọ dị elu, ọ dị ntakịrị ọgwụ a na-edenye ya. Ọ bụrụ na ọnọdụ onye ọrịa ahụ akawanye njọ, ọ ka mma ịjụ ụdị ọgwụgwọ ahụ.

Anabataghị nnabata ma ọ bụrụ na achọpụtara nnukwu imeju. Nke a na - achikọta akụrụngwa na - arụ ọrụ na imeju ma na - enye aka nbibi nke ule ọrụ imeju.

Dodoụbiga ya ókè

Mgbe ị anụbiga mmanya ókè, hypoglycemia na-apụta. Enwere ike idozi ogo dị nfe site na iji shuga ma ọ bụ nri nwere carbohydrate ozugbo. May nwere ike ịchọ ọgwụ ma ọ bụ ndozi nri.

N'okwu ndị dị njọ, yana ọnọdụ amaghị ihe ọ bụla, ọrịa nkwarụ ma ọ bụ coma mamịrị, a na-edozi glucose ma ọ bụ glucagon intramuscularly. Mgbe nke a gasịrị, ọ ga-adị mma inye mmadụ nri n'ụba carbohydrates ngwa ngwa.

N'ime ndị ọrịa nwere nsogbu ịba ọcha n'anya, mkpochapu nke glibenclamide na-abawanye. Ọgwụ ahụ anaghị agwọ ya oke, n'ihi na glibenclamide na-ejikọ nke ọma na protein protein.

A na-eme ka ịdoụbiga mmanya ókè naanị n'ụlọ ọgwụ, mgbe a bịara lactic acidosis. Ihe kachasị dị na nke a bụ hemodialysis.

Mmekọrịta na ọgwụ ndị ọzọ

Ojiji nke miconazole, fluconazole na-enwekwu ohere nke hypoglycemia. Phenylbutazone na-akwụsị ijikọ ihe ndị dị n'ọrụ ka enwere protein protein, nke na-eduga hypoglycemia na mkpokọta ọbara ọbara.

Ọgwụ nwere ọdịnaya ayodiin eji na nyocha X-ray na-akpaghasị ọrụ akụrụ na nchịkọta nke metformin. Nke a na-akpalite omume nke lactic acidosis.

Ethanol na-akpata mmeghachi omume disulfiram. Diuretics belata nsonaazụ nke ọgwụ. Ndị na - egbochi ACE na ndị na - egbochi beta na - ebute ọnọdụ hypoglycemic.

Ejila mmanya mmanya. Nke a na - akpata oke hypoglycemia, na - akpalite mmetụta ndị ọzọ.

Enwere ndepụta analogues nke ọgwụ a, nke yiri ya na ngwa ọrụ arụmọrụ yana nsonaazụ ya:

• Akpa Bagomet,
• Glibenfage
• Glibomet,
• Ndị Gris,
• Gluconorm,
• Gluconorm gbakwunyere,
• Metglib.

Nyocha banyere Metglib Force

Moroz V. A., 38 afọ, endocrinologist, Arkhangelsk: “Ọgwụ dị irè. Ugbu a, m na-agbalị ka m họpụta ya. Ọrịa shuga na-emekwa ndị ọrịa shuga nke ọma, ọ fụta na-enweghị mmetụta ọ bụla. ”

Kozerod A.I., 50 afọ, endocrinologist, Novosibirsk: “Enwere m mmasị na ọgwụ a, ndị ọrịa na-anabata ya nke ọma. M na-ede ya ugboro ugboro, mana tupu oge m ga-aga, m ga-achọpụta ụlọ ọgwụ dị na ya. ”

Veronika, 32 afọ, Moscow: “Mama m arịa ọrịa shuga ogologo oge. Na mbido ọgwụgwọ Glybomet gwọọ ya. Ma mgbe ọ dị mkpa ịbawanye ọgwụ, ọ bịara dị oke ọnụ. Ejiri Metglib Force, nke ọkara dị ọnụ ala dochie gomsomet. Ọgwụ na-arụ ọrụ dị mma, ọbụlagodi mebiri nri. A na-echekwa shuga n'ọkwa nke hypoglycemia anọbeghị ogologo oge. Nanị ihe na-adịghị mma bụ na o siri ike ịchọta n'ụlọ ọgwụ. ”

Roman, onye dị afọ 49, Yaroslavl: “Mgbe shuga m ruru 30 ma m gaa ụlọ ọgwụ na mberede, achọpụtara m ọrịa shuga. Ha bidoro ọgwụ insulin. Amalitere m iso dọkịta ahụ na-eche ma ọ ga-ekwe omume ịgbanwe site na injections gaa na mbadamba mbadamba. Dọkịta ahụ tụrụ aro ịnwale mbadamba Metglib Force. M ji ya afọ 2, afọ juru m. A na-echekwa shuga n'ọkwa, ọ dịbeghị nnukwu mmụba ogologo oge. ”

Valeria, 51 afọ, Chelyabinsk: “A Iụrụ m ọgwụ ahụ ihe dị ka otu afọ. Shuga dịịrị, enweghị hypoglycemia, mana enwere m ahụ ike, enwere ọgbụgbọ mgbe niile. Ọ tụgharịrị na enwere m nsogbu na gland thyroid. Ugbu a, anyị họrọ usoro ọgwụgwọ kwesịrị ekwesị. Dọkịta hapụrụ mbadamba nkume nke Metglib Force. Ọ na-eme ihe dị mma. ”

Ngwá ọgwụ ọgwụ Glibomet

Mlọ ọgwụ Glibomet bụ ngwakọta nke glibenclamide na metformin. Nmekorita nke ihe abuo a bu na enwere mkpali nke zoro ezo nke insulin nke glibenclamide kpatara, na mmụba dị ukwuu na ojiji nke glucose site na anụ ahụ n'ihi ọrụ nke metformin. Nke a na - eduga n'ịme ka arụpụta ihe dị mkpa, nke na - enye ohere belata ọgwụ nke ọgwụ ọ bụla, na --ebelata oke mkpali nke mkpụrụ ndụ β-pancreatic na ohere nke ịmalite ịrụ ọrụ ha, na - ebelata oke ọghọm nke mmetụta ndị ọzọ.
Mlọ ọgwụ Ihe dị ka 84% nke glibenclamide na-abanye na ngọngọ nri. A na-agwakọta imeju ya site na nguzobe nke metabolites na-adịghị ejekwa ọrụ, na-adị na feces na mmamịrị. Ọkara ọkara bụ awa 5. Ogo ogo nke ịdọgide protein ndị dị na plasma bụ 97%.
Metformin, nke a na-ahụ n'ime akwara nri, na-apụ apụ ngwa ngwa na mmamịrị na ọnya, anaghị ejikọ ya na protein ndị dị na plasma, a naghịkwa ahụ ya n'ahụ. Ọkara ọkara bụ ihe dịka awa 2.

Ojiji ogwu Glibomet

A na-ekpebi ị dailyụ ọgwụ kwa ụbọchị yana oge dọkịta site na steeti metabolic steeti onye ọrịa. Ọgwụ nke mbụ maka ndị okenye na-abụ mbadamba mbadamba abụọ kwa ụbọchị (were 1 mbadamba ụtụtụ na mgbede na nri), kwa ụbọchị ịgaghị agafe mbadamba isii (mbadamba 2 ugboro atọ n'ụbọchị nri). Denye na ntakịrị opekempe, na-enye njikwa zuru oke nke glycemia. Enwere ike iji nwayọ belata oge kwa ụbọchị ka oge na-aga ruo mgbe opekempe nke ga-ezu iji chịkwaa glucose ọbara.

Nsonaazụ nke ọgwụ Glibomet

N'ọnọdụ ndị a na-adịghị ahụkebe, mmepe nke hypoglycemia ga-ekwe omume, karịsịa na ndị ọrịa nwere nsogbu, ndị agadi, na-arụ ọrụ anụ ahụ na-adịghị ahụkebe, yana iri nri na-adịghị adị ma ọ bụ na-a drinkingụ mmanya, ma ọ bụrụ na umeji na / ma ọ bụ ọrụ akụrụ. Mgbe ụfọdụ enwere isi ọwụwa, nsogbu nke eriri afọ: ọgbụgbọ, anorexia, gastralgia, vomiting, afọ ọsịsa, na-achọ ịkwụsị ọgwụgwọ. Mgbe ụfọdụ, mmeghachi omume nfụkasị anụ ahụ na-etolite, na-abụkarị nwa oge ma na-apụ n'anya onwe ya site na iji ọgwụgwọ na-aga n'ihu. Okwu ikpe a kọwara na akwụkwọ nke ike omume metabolic acidosis n’oge ọgwụgwọ metformin adịkarịghị ukwuu. Agbanyeghị, egosipụtara ya na ndị ọrịa nwere ihe ndị dị ize ndụ, dịka akụrụ gbasara akwara na ọrịa obi, ọnọdụ a nwere ike ibute ụzọ ọsọ ọsọ ma ọ bụrụ na akwụsịghị ọgwụgwọ ahụ ozugbo anaghi ewere usoro ọgwụgwọ kwesịrị ekwesị. A kọwo ọnọdụ nke mmụba nke lactic acid na ọbara ọbara, mmụba na ọnụọgụ nke lactate / pyruvate, mbelata ọbara pH na hyperazotemia (a kọwara ọnọdụ ndị ọrịa maka ọrịa na-adịghị mma nke ọrịa shuga mellitus). Mmepe nke metabolic acidosis nwere ike iduga n'otu oge mmanya na-egbu egbu n'oge ọgwụgwọ ọgwụ. Hematopoiesis bụ nke dị ụkọ ma ọ na - agbanwegharịkarị.

Mkparịta ụka ọgwụ ọjọọ Glibomet

Mmetụta hypoglycemic nke glibenclamide bụ nke dicumarol na ihe ndị ọ na-eme, MAO inhibitors, ọgwụ sulfonamide, phenylbutazone na ihe ndị dị na ya, chloramphenicol, cyclophosphamide, probenecid, pheniramin, salicylates, miconazole for abile management, sulfinpy. Nsonaazụ nke glibenclamide nwere ike ịda mba n'iji epinephrine, corticosteroids, ọgwụ mgbochi, thiazide diuretics na barbiturates n'otu oge. Ekwesịrị iji nlezianya mee ihe mgbe ị na-eji ndị na-anabata β-adrenergic nwere mgbochi. Ekwesịrị iburu n'uche na biguanides nwere ike ịkwalite nsonaazụ anticoagulants.

Etu esi eji: usoro onunu ogwu na usoro ọgwụgwọ

A na-ewere ọgwụ ọnụ, ya na nri. A na-ahọrọ usoro usoro usoro nke Metglib n’otu n’otu, dabere na steeti metabolism.

Dị ka ọ na-adịkarị, usoro mbụ nke Metglib bụ mbadamba 1 (2.5 mg glibenclamide na 500 mg metformin), yana usoro nke iji nwayọọ nwayọọ na-eme ihe ọ bụla ruo izu 1-2 ọ bụla, dabere na ndepụta glycemic.

Mgbe ị na-eji metformin na glibenclamide dochie usoro ọgwụgwọ gara aga, a na-enye mbadamba 1-2 (2.5 mg glibenclamide na 500 mg metformin), dabere na usoro gara aga nke akụkụ ọ bụla.

Oke kachasị kwa ụbọchị bụ mbadamba 4 (2.5 ma ọ bụ 5 mg nke glibenclamide na 500 mg nke metformin).

Mwepụta wepụtara ya na ihe mebere

Ọ dị n'ụdị mbadamba biconvex okirikiri kpuchie na shei ọcha. Mbadamba ụrọ na-achịkọta mbadamba iri abụọ. A na-ere ha n'ime paịlị ngwugwu nke blisters 2, 3 ma ọ bụ 5.

Ntụziaka maka iji Glibomet (usoro na usoro onunu ogwu)

Dọkịta setịpụrụ usoro usoro oge ọ ga-esi na-agwọ ya iche iche, dabere n'ọbara shuga dị n'ọbara ya na steeti metabolism ya.

Ọgwụ nke mbụ kwesịrị ịbụ mbadamba mbadamba 1-3 kwa ụbọchị, ndị na-esochi usoro iji ọgwụ eji arụ ọrụ kachasị arụ ọrụ.

Iri ugboro abụọ n’ụbọchị n’oge nri ụtụtụ na nri abalị. Dosebọchị kwa ụbọchị dị ka ntuziaka ahụ si dị gafere 6 mbadamba.

Mkparịta ụka ọgwụ ọjọọ

• Enwere ike ịbawanye hypoglycemic nke ọgwụ ahụ ka ị na-ewere ya na dicumarol na ihe ndị dị na ya, beta-blockers, cimetidine, oxytetracycline, sulfanilamides, allopurinol, MAO inhibitors, phenylbutazone na ọgwụ ya, probenecid, chloramphenicol, salicylinone anionone nnukwu.
• Nsonaazụ nke ọgwụ nwere ike wedata yana ijikọ ya na epinephrine, homonụ thyroid, glucocorticoids, barbiturates, thiazide diuretics na ọgwụ mgbochi.
• Site na iji ọgwụ ahụ n'otu oge eji anticoagulants, mmụba na nsonaazụ nke ikpeazụ ga-ekwe omume.
• Mgbe ejiri ya cimetidine, nsogbu nke ịmalite lactic acidosis na-abawanye.

Ọnụahịa dị na ahịa ọgwụ

Ọnụahịa Glibomet maka ngwugwu 1 na-amalite site na 280 rubles.

Nkọwa dị na ibe a bụ ụdị dị mfe nke nkọwapụta ọgwụ ọgwụ. Enyere ozi a maka ebumnuche gbasara ọfụma ọ bụghị ntuziaka maka ọgwụ ịchọrọ onwe gị.Tupu ị usingụ ọgwụ ahụ, ị ​​ga-agakwuru onye ọkachamara ma mara onwe gị na ntuziaka nke onye nrụpụta kwadoro.