Ọgwụ Dimaril: ntuziaka maka ojiji > Ọgwụgwọ na mgbochi

Isi, ihe na-arụ ọrụ bụ Diphenhydramine. Usoro nke usoro a dabere na mmetụta inhibitory nke ọgwụ ahụ na etiti, akụkụ cholinergic, na igbochi ndị na-anabata H3-histamine na ụbụrụ. Diphenhydramine na-eme ka ahụ mgbu dị nro, edema anụ ahụ, hyperemia, na - egbochi spasms nke anụ ahụ dị nro, nwere ezigbo mmetụta na ike ọchịchị zuru oke. Iwere udiri ekwu okwu na-eme ka odi mkpirikpi oge n'ime oghere onu. Ọgwụ ahụ nwere ọgwụ antiparkinsonian, hypnotic, sedative, mmetụta antiemetic. N'ihi igbochi ndị na-anabata cholinergic, ganglia na-ebelata ọbara mgbali, ma nwee ike ịba ụba nke dị hypotension. N’ime ndị nwere àkwụkwụ na mmebi ụbụrụ nke mpaghara, ọbụna usoro Diphenhydramine dị ala nwere ike ịkpasu iwe Akwụkwụ na-adọ adọ, na EEG nke mbubreyo nke ọrịa akwụkwụla kwuru. Ọgwụ kachasị dị irè na bronchospasmkpasuru iwe site na iji akwukwo nnwere mmuta (morphine, tubocurarine). Ọgwụ bụ opekempe karịa maka bronchospasm nke mkpụrụ ndụ ihe nfụkasị. Site na iji usoro ugboro ugboro, ọgwụ ịrahụ ụra na nsonaazụ izu ike ka a na-ekwupụta. Ọgwụ na-amalite ime otu elekere mgbe mmịnye ahụ, nsonaazụ dị mma na-adịgide ruo awa 12.

Mwepụta wepụtara ya na ihe mejupụtara

Usoro onunu ogwu nke diphenhydramine:

Mbadamba ụrọ: ọcha, okirikiri ewepụghị cylindrical udi nwere bevel (PC 10.) N'ihe dị warara, na ngwugwu nke 1, 2, 3 ma ọ bụ 5, ngwugwu 10. Na ngwugwu bezeljacheykovy, na akpa akwụkwọ 1 mkpọ ma ọ bụ na kaadiboodu 1, 2 ma ọ bụ atọ, ngwugwu 10. Ma ọ bụ pọọsụ 20. N'ime iko gbara ọchịchịrị, na ngwungwu kaadiboodu 1 nwere ike),
Ngwọta maka intravenous (m / v) na nchịkwa intramuscular (m / m): mmiri na-enweghị paịlị na ampoules nke 1 ml (pcs 5.) N'ime ngwugwu na-acha uhie uhie, na igbe kaadi 1 ma ọ bụ 2 ngwugwu, pọọsụ 10. 10 pcs. Na bliri mpempe ngwugwu, na kaadiboodu ukwuu 2 ngwugwu, 10 PC. Na a blister mkpọ, na kaadiboodu ukwuu 1 mkpọ).

Mbadamba ụrọ: diphenhydramine hydrochloride, na 1 pc. - 50 mg
Ngwọta: diphenhydramine, na 1 ml - 10 mg.

Mbadamba ụrọ: methyl cellulose mmiri - 0.326 mg, lactose monohydrate (shuga mmiri ara ehi) - 75 mg, colloidal silicon dioxide (aerosil) - 0.76 mg, ọka ọka - 23.154 mg, stearic acid - 0.76 mg,
Ngwọta: mmiri maka injection.

Ihe ngosi maka ojiji

Ihe nfụkasị ahụ, gụnyere fever hay, urticaria, angioedema,
Ọbara vasculitis,
Allergic conjunctivitis,
Ọrịa ọbara
Chorea
Vasomotor rhinitis,
Itchy dermatoses,
Nsogbu ihi ụra, dị ka monotherapy ma ọ bụ yana ọgwụ ịrahụ ụra.
Vomiting ime
Ihu ikuku na oké osimiri,
Ọrịa Meniere,
Ọkpụkpọ.

Ihe ngbanwe

Ọrịa afọ nke duodenum na / ma ọ bụ afọ,
Asmara,
Mkpuchi mmechi nke Angle,
Afọ ime,
Hypertrophy nke prostate gland,
Akwụkwụ na-adọ
Hypersensitivity na diphenhydramine.

N'ilekọta anya ma gosipụta ihe doro anya, edere diphenhydramine n'oge afọ ime yana n'oge a na-enye nwa ara, naanị ma ọ bụrụ na uru nne elere anya ga-akacha karịa ihe nwere ike ibute nwa ebu n’afọ.

Usoro onunu ogwu na nhazi

Mbadamba: were ọnụ. Singchọ maka ndị ọrịa toro eto: dị ka ọgwụ ụra - 50 mg n'oge ụra, ọgwụgwọ - 30-50 mg 1-3 ugboro n'ụbọchị, maka ụbọchị 10-15. Maka ụmụaka, otu mkpụrụ ọgwụ bụ: ruo 1 afọ - 2-5 mg, site na afọ 2 ruo 5 - 5-15 mg, site na afọ 6 ruo 12 - 15-30 mg,
Ngwọta maka nchịkwa intramuscular: maka ndị ọrịa toro eto, ntụtụ intramuscular na ọnụọgụ 50 ruo 250 mg, ntapu intravenous - 20-50 mg. Atugharị atọrọ ka 1-2 ugboro ụbọchị.

Nsonaazụ

Ojiji diphenhydramine nwere ike ibute nsonaazụ:

Ikekwe: iro ụra, obere mkpụmkpụ nke mucosa nke ọnụ, belatara nlebara anya, adịghị ike n'ozuzu ya, na ụmụaka - mmepe nke nsogbu nke ehighị ụra nke ọma, akwara na iwe,
Oge na-adịkarị: isi ọwụwa, nkụda mmụọ, ọrụ mkpụkọ nke mmeghari, ọgbụgbọ, ọnụ na-egbu egbu, fotoensitivity, ịma jijiji, paresis ụlọ.

Ntụziaka pụrụ iche

A na-atụ aro onye ọrịa mgbe oge ị ofụ ọgwụ iji zere ikpughe radieshon anyanwụ, ọ dị mkpa ịhapụ ị toụ mmanya.

N'oge ime na inye nwa ara, ekwesịrị iji ọgwụ ahụ mee ihe n'okpuru nlekọta ahụike.

Edere ya nke ọma na ndị ọrịa metụtara ụdị ọrụ dị oke egwu, mmejuputa iwu nke chọrọ mmeghachi omume psychomotor ngwa ngwa na nlebara anya elebara anya.

Mkparịta ụka ọgwụ ọjọọ

Ojiji nke diphenhydramine na-abawanye ọrụ nke ọgwụ ndị na-egbochi usoro ụjọ ahụ, na-eme ka ethanol rụọ ọrụ.

Njikọ ya na ndị na-egbochi monoamine oxidase (MAO) na-abawanye ọrụ anticholinergic nke ọgwụ.

Mmeghachi omume na-emegide ihe dị na mmalite nke oge njikọta nke njikọta na psychostimulants.

Ojiji n’otu oge iji ọgwụ eme ihe na-ebelata mmetụta mmetụta nke apomorphine na ọgwụ nke nsị.

Ọgwụ na-abawanye mmetụta anticholinergic nke ọgwụ anticholinergic.

Analogs nke Diphenhydramine bụ: Diphenhydramine-ROS, Diphenhydramine-UBF, Diphenhydramine-UVI, Diphenhydramine-Vial, Diphenhydramine Bufus, Dramina, Kalmaben.

Diphenhydramine: ọnụ ahịa dị na ahịa ọgwụ dị n'ịntanetị

DIMEDROL 50mg 10 PC. ọgwụ

Diphenhydramine 50 mg mbadamba 10 pcs.

DIMEDROL 50mg 10 PC. ọgwụ

DIMEDROL 50mg 20 PC. ọgwụ

Diphenhydramine 50 mg mbadamba 20 pcs.

Diphenhydramine 50mg Nke 20

Diphenhydramine (maka ọgwụ ntụtụ) 10 mg / ml maka nchịkwa mgbochi intramuscular 1 ml 10 PC.

DIMEDROL 10mg / ml 1ml 10 PC. nwara intramuscular

Diphenhydramine (maka ọgwụ ntụtụ) 10 mg / ml maka nchịkwa mgbochi intramuscular 1 ml 10 PC.

DIMEDROL 10mg / ml 1ml 10 PC. ngwọta maka nchịkwa intravenous na intramuscular

A na - emejupụta ozi gbasara ọgwụ ahụ, enyere ya aka ka ọ nweta ihe ọ bụla, ọ naghị edochi ntuziaka gọọmentị. Medication medicationụ onwe gị ọgwụ dị ize ndụ nye ahụ ike!

Ọrịa kacha egbu egbu bụ ọrịa Kuru. Naanị ndị nnọchi anya ebo ebo dị na New Guinea na-arịa ọrịa. Ọ na-achị ọchị chịa onye ọrịa. Ekwenyere na ihe kpatara ọrịa ahụ na-eri ụbụrụ mmadụ.

Dabere na ọtụtụ ndị ọkà mmụta sayensị, usoro ihe ọmụmụ vitamin abaghị uru ụmụ mmadụ.

Nwa nwoke onye Australia dị afọ 74, James Harrison ghọrọ onye na-enye ọbara n'ihe dị ka 1,000 ugboro. O nwere ụdị ọbara dị ụkọ, ọgwụ mgbochi nke enyere ụmụ amụrụ ọhụrụ aka na-arịa oke anaemia. N'ihi ya, onye Australia chebere ihe ruru ụmụaka nde abụọ.

Onye ọ bụla nwere ọ bụghị naanị mkpụrụ aka dị iche, kamakwa asụsụ.

N'oge ndụ, nkezi onye na-amịpụta obere mmiri mmiri abụọ.

Mpekere chọkọleti anọ gbara ọchịchịrị nwere ihe dị ka calorie narị abụọ. Yabụ ọ bụrụ na ịchọghị ịka mma, ọ ka mma ịghara iri karịa lobules abụọ kwa ụbọchị.

Ọbara mmadụ "na-agabiga" n'ime arịa ndị nọ n'okpuru nrụgide dị ukwuu, ọ bụrụ na e mebiri iguzosi ike n'ezi ihe ya, ọ nwere ike gbaa 10 mita.

Ndị mmadụ na-eri nri ụtụtụ mgbe niile yikarịrị ka hà buru oke ibu.

Onye na-a antụ ọgwụ mgbochi n’oge ikpe ga-enwetakwa ịda mbà n’obi ọzọ. Ọ bụrụ na mmadụ anagide nkụda mmụọ na aka ya, ọ nwere ohere ọ bụla ichefu ọnọdụ a ruo mgbe ebighi ebi.

Dabere na ọmụmụ, ụmụ nwanyị ndị na-a severalụ ọtụtụ iko biya ma ọ bụ mmanya n'izu, ha nwere ohere dị ukwuu nke ịrịa ọrịa cancer ara.

Na mgbakwunye na ndị mmadụ, naanị otu ihe dị ndụ na mbara ụwa - nkịta, na-arịa ọrịa prostatitis. Ndị a bụ ndị enyi anyị kacha kwesị ntụkwasị obi.

E dere temprechọ kachasị elu na Willie Jones (USA), onye nabatara n'ụlọ ọgwụ ahụ na-enwe 46.5 Celsius.

N'oge ịsụgharị, ahụ anyị na-akwụsị ịrụ ọrụ kpamkpam. Ọbụna obi na-akwụsị.

Ọrụ mmadụ na-enweghị mmasị na ya bụ ihe na-emebi mmụọ ya karịa enweghị ọrụ ma ọlị.

Ọ bụrụ na ị na-amụmụ ọnụ ọchị naanị ugboro abụọ n'ụbọchị, ịnwere ike belata ọbara mgbali ma belata ihe egwu nkụchi na ọnya afọ.

Ezigbo ezé ezé ma ọ bụ ọbụna adentia zuru oke nwere ike ịbụ nsonaazụ nke mmerụ ahụ, caries ma ọ bụ ọrịa chịngọm. Ma, enwere ike dochie ezé furu efu na ezé.

Gịnị bụ diphenhydramine

Dabere na nhazi ahụike a nabatara, Diphenhydramine bụ nke ndị na - egbochi ọgwụ mgbochi na ọgwụ antiallergic. Ihe na-arụ ọrụ nke ihe mejupụtara bụ diphenhydramine hydrochloride, nke na-arụ ọrụ na sistemụ akwara, na-egbochi ndị na-anabata ụbụrụ akwara. N'ihi nsonaazụ a, a na-ewepụ spasm nke akwara ndị dị larịị, enwere ahụ efe nke ọnọdụ onye ahụ na allergies.

Ngwakọta na ụdị ntọhapụ

Maindị isi nke ịhapụ ọgwụ bụ ngwọta ntụtụ na mbadamba. Enwere ike iburu nke mbụ ya ọnụ ma ọ bụ tinye ya na anya. Na mgbakwunye, a na-emepụta supurelial rectal dabere na ihe ndị nọ n'ọrụ. Egosiputara ihe ngosi na nkowa nke nkwadebe di na tebụl:

White flat cylindrical with a facet and a risk

Ntinye uche nke diphenhydramine, mg

30, 50 ma ọ bụ 100 kwa 1 pc / 20 maka ụmụaka

Mmiri dị ọcha maka ntụtụ

A na-akpọ stearic acid, stachi nduku, colloidal silicon dioxide, lactose

Ampoules nke 1 ml, 10 PC. na ngwugwu nwere ntuziaka maka ojiji

Blisters ma ọ bụ mpempe 6 ma ọ bụ 10 PC., Akwa nke otu ọnya ọ bụla

Njirimara ọgwụ kemịkal nke diphenhydramine

Ọgwụ ahụ metụtara ndị na - egbochi ndị na - anata ya na ụbụrụ. N'ihi nke a, diphenhydramine na-ebelata spasm nke akwara ndị dị larịị, na-ebelata ikike mkpụrụ ndụ, na-ebelata ike nke mmeghachi omume nfụkasị. Substanceme ihe na - arụ ọrụ nke ịkwadebe ọgwụ anestetiiki dị n’ime ya nwere ọgwụ mgbochi, mmetụta ogwugwo, mmetụta hypnotic.

Ọgwụ a na-ebute mgbatị mpaghara, nke na-egosipụta onwe ya na oge dị mkpirikpi nke ọnya ọnya ọnụ, nwere mmetụta antispasmodic. Diphenhydramine dị irè karị ma a rụpụta ihe na - akpata bronchospasm nke ndị na - eme ya na ihe na - akpata oke ala. Ọgwụ ahụ enweghị ọgwụ ọria megide ụkwara ume ọkụ bronchial, enwere ike ijikọ ya na ndị na-ahụ maka akwara (Theophylline, Ephedrine).

Diphenhydramine na-emegide mmetụta nke histamine, na-eme ka ọbara mgbali elu. N'ime ndị ọrịa nwere erughi oke olu ọbara, njikwa parenteral nke diphenhydramine nwere ike ime ka mbelata mgbali ma bulie hypotension n'ihi nsonaazụ ganglion. Site na mmebi mpaghara nke ụbụrụ na Akwụkwụ na-adọ, ọgwụ ahụ nwere ike ime ka mwepu akpa arụ ma kpasuo ọgụ nke Akwụkwụ na-adọ.

Ọgwụ na-amalite ime ihe na nkeji ole na ole, mmetụta ya dịruru ruo awa 12. Diphenhydramine na-ejikọ protein protein plasma site na 98%, bụ metabolized na imeju, akpa ume na akụrụ, nke akụrụ na-enye ya, na mmiri ara ara n'ụdị conjugate metabolites na glucuronic acid. Arụ ọrụ nke mejupụtara ahụ na-abanye n'ọbara nke ụbụrụ, a na-ahụ ọnụọgụ nke mmiri ara.

Otu na-ere ọgwụ:

Koodu ATX R06AA02

Omume ọgwụ
Ihe mgbochi nke ndị natara H1-histamine nke ọgbọ mbụ. Na-egbochi ndị nnabata H1-histamine ma kpochapụ nsonaazụ nke histamine nke dị na ụdị nnata a. Actionrụ ọrụ na sistemụ akwara na-egbochi mmachi nke N₃- ndị na - anabata ụbụrụ ụbụrụ na mgbochi nke akụkụ akwara dị iche iche. O nwere ihe anakpokọ antihistamine, na -ebelata ma ọ bụ na - egbochi akwara spamms, ịbawanye ụba nke ọnya, ọsịsọ na ahụ. Ọ na - ebute mgbatị mpaghara (mgbe ejiri ọnụ, ọnụọgụ mkpụmkpụ nke mucous nke olu a na - eme), na - egbochi ndị na - anabata ganglia cholinergic (na - agbada ọbara mgbali) na usoro akwara nke etiti, ma nwee ọgwụ mgbochi, hypnotic, antiparkinsonian na antiemetic. A na-egosipụta nkwuputa ọgụ na anakpo histamine n'ụzọ dị ukwuu n'ihe gbasara mmeghachi omume vaskụla mpaghara na mbufụt na nfụkasị karịa nke ndị nwere usoro, i.e. na-ebelata ọbara mgbali elu. N’ime ndị nwere ụbụrụ ọgbụgba na mpaghara, ọ na - eme ọsịsọ (ọbụlagodi obere nzere) ọria mmiri na EEG ma nwee ike ịkpalite ọdịkwụkwụ. A na-ekwukarị ọgwụ mgbochi na hypnotic site na iji ọgwụ ugboro ugboro.
Oge mmalite nke ihe a ga-achọpụta na nkeji 15-60 mgbe mmachibido ahụ gasịrị, oge nke -12 awa

Mlọ ọgwụ
Gbasoro ngwa ngwa na eriri afọ. Bioavailability bụ 50%. TCmax - 2040 min (a na-ekpebi itinye uche kachasị elu na ngụgụ, akwara, akụrụ, imeju, ụbụrụ na akwara). Nkwukọrịta na protein protein - 98-99%. Penetrates site na mgbochi ụbụrụ ọbara. Ọ bụ metabolized kachasị na imeju, akụkụ ụfọdụ na ngụgụ na akụrụ. Site na anụ ahụ ka ọ gachara awa 6. Nkeji ọkara bụ awa 4-10. N’ehihie, akụrụ ya ga-apụ n’onwe ya n’ụdị metabolites ndị a gwakọtara ya na glucuronic acid. A na-apịpụta mmiri ara ehi dị mkpa ma nwee ike ibute nsị nwa (a ga-ahụ mmeghachi omume dị iche iche na-egosipụta oke ike).

Ihe ngosi maka ojiji
Ọrịa Allergic conjunctivitis, rhinitis nfụkasị, urticaria na-adịghị ala ala, ọrịa pruritic dermatoses, dermatographism, ọrịa serum, na usoro mgbagwoju anya nke mmeghachi omume anaphylactic, Quincke edema na ọnọdụ nfụkasị ndị ọzọ.
Insomnia, chorea, ọrịa Meniere, ọrịa oké osimiri na ikuku, dịka ọgwụ mgbochi.

Ihe ngbanwe
Hypersensitivity, glaucoma akụkụ akụkụ, mmechi hyperplasia, ụkwara ọnya afọ na duodenum, stenosis nke ọnya afọ, ụkwara ume ọkụ, ụkwara ume ọkụ.
Afọ ụmụaka ruru afọ asaa (maka ụdị usoro a).

Jiri nlezianya - afọ ime, lactation.

Usoro onunu ogwu na nhazi
N'ime. Ndị okenye na ụmụaka karịrị afọ 14, 25-50 mg (1 / 2-1 mbadamba) ugboro 1-3 n'ụbọchị. Otu kachasị elu bụ 100 mg, kwa ụbọchị - 250 mg. Na nsogbu ehighị ụra - 50 mg 20-30 nkeji tupu ụra. Na ọrịa ngagharị - 25-50 mg kwa awa 4-6 ọ bụrụ na ọ dị mkpa.
Frommụaka sitere na afọ 7 ruo 14 afọ 12.5 - 25 mg (1 / 4-1 / 2 mbadamba) 1-3 ugboro n'ụbọchị.

Mmetụta akụkụ
Mgbu, akpịrị ịkpọ nkụ, ọnụọgụ nke mucosa a na-ede ede, nkụda mmụọ, ụjọ, ọgbụgbọ, isi ọwụwa, adịghị ike nke izugbe, mbelata nke mmeghachi omume psychomotor, fotoensitivity, paresis nke ebe obibi, nhazi nke mmegharị. N’aka umuaka, mmepe ihe ndi n’emeghi ura nke ehughi ura, iwe na ogba aghara omume.

Dodoụbiga ya ókè
Ọrịa ịda mba nke usoro akwara ozi, mmepe nke obi ụtọ (ọkachasị na ụmụaka) ma ọ bụ nkụda mmụọ, ụmụ akwụkwọ etinyere ya n’olu, ọnụ na-egbu, paresis nke akụkụ nke eriri afọ, wdg.
Ọgwụgwọ: ọ nweghị ọgwụ pụrụ iche. Gvric lavage. Ọ bụrụ na ọ dị mkpa, ọgwụgwọ Symptomatic: ọgwụ ndị na-abawanye ọbara mgbali, oxygen, nchịkwa akwara nke mmiri mmiri ga-anọchi plasma.
Ejila epinephrine na analeptics.

Mmekọrịta na ọgwụ ndị ọzọ
Na-emeziwanye ihe ethanol na ọgwụ ndị na-egbochi sistemụ akwara.
Ndị na-egbochi Monoamine oxidase na-akwalite ọrụ anticholinergic nke diphenhydramine.
A na-ahụta mmekorita nke Antagonistic na oge njikọta na psychostimulants.
Na-ebelata ịdị irè nke apomorphine dị ka mkpụrụ ndụ ihe nketa na ọgwụgwọ nke nsị.
Na-eme ka anticholinergic mmetụta ọgwụ ike na ọrụ anticholinergic.

Ntụziaka pụrụ iche
Ọ dị mkpa ịkpachara anya maka ndị ọrịa na-eme ihe nwere ike ibute ọrịa chọrọ nlebara anya na mmeghachi omume nke mmụọ ngwa ngwa. N'oge ọgwụgwọ diphenhydramine, ekwesịrị ịhapụ ikpughe anyanwụ na ethanol.
Ọ dị mkpa ịgwa dọkịta banyere iji ọgwụ a: mmetụta antiemetic nwere ike ịme ka nchọpụta nke appendicitis na njirimara nke akara nke ị ofụ ọgwụ ndị ọzọ.
N'ime ụmụaka site na 1 afọ ruo afọ 7, a na-atụ aro iji mbadamba 30 mg (site na 1 afọ ruo afọ 3), ọgwụ kwa ụbọchị nke 10-30 mg, kewara n'ime usoro 2-3, site na afọ isii ruo afọ 6, kwa ụbọchị nke 20 - 45 mg, kewara 2 -3 nnabata).
N'ime ụmụaka site na ọnwa 7 ruo ọnwa iri na abụọ, enwere ike iji ọgwụ ahụ mee ihe n'ụdị ntụ ọka a kwadebere na ụlọ ọrụ ọgwụ yana mmepụta nke ọgwụ ọgwụ 3-5 mg ugboro abụọ n'ụbọchị.

Mpempe mwepụta
Mbadamba 50 mg
Na mbadamba 10 na ngwungwu na-enweghị ọnya ma ọ bụ na ngwugwu ọnya. Na 2, 3 ma ọ bụ 5 pịrị ọnụ paịlị ọnụ yana ntinye akwụkwọ etinye na mkpọ n'ime kaadiboodu.

Exbọchị mmebi
Afọ 5 Ejila ọgwụ ahụ mgbe ọ gwụchara.

Ọnọdụ nchekwa
Detuo B. Na ebe kpọrọ nkụ, ebe gbara ọchịchịrị na ebe ụmụaka na-agaghị eru ha.

Okwu ezumike
Site na ndenye ọgwụ.

Claim emeputa / nzukọ:
OJSC "Dalhifarm"
680001, Khabarovsk, St. Tashkent, 22.

Omume ọgwụ

O nwere antihistamine, antiallergic, antiemetic, hypnotic, mmetụta anestetiiki mpaghara. Na-egbochi akụkọ histamine H₁ - ndị na - anabata ya ma kpochapụ nsonaazụ nke histamine nke dị na ụdị nnata a. Na -ebelata ma ọ bụ na - egbochi akwara dị n'akamamam ahụ akwara, ịba ụba anụ ahụ, akụkụ ahụ, pruritus, na hyperemia. Egosiputa anakpo anagide na akuko ananu gosiputara na oke ihe banyere mmeghachi omume vaskụla n’obodo n’enwe mbufụt na ahuhu dika ndi nke system, i.e. na-ebelata ọbara mgbali elu. Ọ na - ebute ịwa ahụ mpaghara (mgbe a na -ekwu ya ọnụ, enwere obere oge nke ọnụọgụ mucosa), na-enwe mmetụta antispasmodic, na-egbochi ndị na-anabata cholinergic nke autonomic ganglia (na-ebelata ọbara mgbali). Nkanka₃ - ndị na - anata ụbụrụ nke ụbụrụ ma na - egbochi ihe ndị dị n’ime ala. O nwere ogwuura, hypnotic na antiemetic. Ọ na-arụ ọrụ nke ọma maka nsị bronchospasm nke ndị na-eme ka a na -akpata ya (tubocurarine, morphine, sombrevin), na-erughị obere maka bronchospasm nfụkasị. Na ashma, ọ naghị arụ ọrụ ma ejiri ya na theophylline, ephedrine na bronchodilato ndị ọzọ.

Mlọ ọgwụ

Mgbe e ji ọnụ kwuo ya, ọ na-agbadata ngwa ngwa. Ọ jikọrọ protein na plasma site na 98-99%. Oke ịta (C_tah) n'ime plasma na - enweta ihe elekere anya elekere 1-4 mgbe ịbanyesịrị. Ọtụtụ n'ime diphenhydramine a na-agara n'ime imeju. Nkera-ndu (T_1/2) bụ awa 1-4. Ọ na - ekesasịkwa ahụ niile, na-agafe ihe mgbochi nke ụbụrụ ọbara na Plasenta. Oke mmiri ara ehi nwere ike bute nsị n'ime ụmụ ọhụrụ. N'ehihie, ọ na - apụ ya kpamkpam site n'ụdị nke benzhydrol nwere glucuronic acid, ma ọ bụ naanị na obere ego - anaghị agbanwe agbanwe. Mmetụta kasịnụ na-etolite 1 awa mgbe ịbatara, oge ọ ga-amalite bụ site awa anọ ruo awa isii.

Mmetụta akụkụ

Site na sistemụ akwara na akwara anụ ahụ: adịghị ike n'ozuzu ya, ike ọgwụgwụ, mmetụta ịda mba, belatara nlebara anya, obi ilu, ụra, isi ọwụwa, nhazi nke mmegharị, nchekasị, oke mgbakasị ahụ (ọkachasị na ụmụaka), ahụ erughị ala, ahụma jijiji, ehighi ura, ụjọ, ọgba aghara, ọgba aghara , ụjọ, neuritis, nkwarụ, paresthesia, nkwarụ ọhụhụ, diplopia, nnukwu labyrinthitis, tinnitus. N'ime ndị ọrịa nwere mmebi ụbụrụ mpaghara ma ọ bụ Akwụkwụ na-adọ, ọ na-eme ka ọ dị (ọbụlagodi obere doses) mwepu ọbara na EEG ma nwee ike ịkpasu ọdịdọ ahụ.

Site na sisitemu obi na obara: hypotension, palpitations, tachycardia, extrasystole, agranulocytosis, thrombocytopenia, hemolytic anemia.

Site na ngwara nri: ọnụ akpọnwụ, ọnụọgụ nke mkpụkpụ mucosa, anorexia, ọgbụgbọ, nsogbu ọgbụgba, ọgbụgbọ, afọ ọsịsa, afọ ntachi.

Site na usoro mkpụrụ ndụ: urination ugboro ugboro na / ma ọ bụ sie ike, njigide nke urinary, mbido mbụ ya.

N’akụkụ akụkụ akụkụ iku ume: imi na akpịrị afọ, mkpọchi imi, na-eme ka mmiri na-egbu ume, na -emechi obi na iku ume.

Mmeghachi omume nfụkasị ahụ: ihe ọkụ ọkụ, urticaria, ujo ụjọ.

Ndị ọzọ: ọsụsọ, akpata oyi, fotoensitivity.

Dodoụbiga ya ókè

Ọrịa: akpọnwụ akpọnwụ, nsogbu iku ume, mydriasis na-adịgide adịgide, nsị ihu, nkụda mmụọ ma ọ bụ nsogbu (karịa mgbe ọ bụla na ụmụaka) nke sistemụ etiti, ọgba aghara, na ụmụaka - mmepe nke ihe ọdịdọ na ọnwụ.

Ọgwụgwọ: ịkpali ọgbụgbọ, ọnya afọ, nchịkwa nke unyi na-arụ ọrụ, usoro ọgwụgwọ na usoro nkwado na iji nlezianya nyochaa iku ume na ọbara mgbali.

Na ọgwụ

Maka ndị okenye, a na-ewere mbadamba Diphenhydramine na 30-50 mg 1-3 ugboro / ụbọchị na oge 10-15. Otu ogwu maka ụmụaka na-erubeghị afọ 2-5 mg, nwatakịrị nke dị afọ 2-5 kwesịrị ịnata 5-15 mg, 6-12 afọ - 15-30 mg. A na-eji Diphenhydramine dị ka ọgwụ ihi ụra 50 mg n'oge ụra. Ọ gaghị ekwe omume ịgabiga usoro ọgwụ dọkịta nyere maka ịba ụba nke ohere nke nzaghachi na-adịghị mma. Mbadamba mmiri ga-eji mmiri washedacha, were ya n'agbanyeghị nri.

N'okpuru aha "Diphenhydramine" suppositories anaghị adị, mana enwere suprititories maka ojiji mmegharị nwere analginhydramine dịka ọmụmaatụ, Analdim. A na-eji ha eme ihe dị ka ọgwụ eji agwọ anụ mgbe ọ sachara enema, etinyere ya n’akpụ ụkwụ ugboro abụọ n’ụbọchị. Mụaka 1-4 dị afọ ka etinyere otu ikike, okenye - 1-3 suppositories. Nwatakịrị nwatakịrị dị obere, a ga-etinye ike itinye uche nke ihe ndị dị n'ọrụ. Usoro ọgwụgwọ ya dị ụbọchị iri na anọ.

Maka iji ophthalmology ma ọ bụ allergology, edepụtara diphenhydramine tụlee. Maka nke a, 0.2-0.5% n'ime ụdị 2% nke boric acid na-etinye 1-2 n'agbata oge 3-5 na ụbọchị iji mee ka mmeghachi ahụ nfụkasị ahụ kwụsị. Enwere ike ịgwọta azịza ya intranasally, iji kpochapụ ihe mgbaàmà nke rhinitis nfụkasị na sinusitis - 0.05 ml nke ọgwụ dị na imi ọ bụla ọtụtụ ugboro / ụbọchị. Ọ ga-ekpebi ụzọ dọkịta ga-esi gwọọ ya, ọ kọkwaara ya etu esi agwọ ọgwụ ahụ.

Diphenhydramine n’oge di ime

Ndị dọkịta na-edepụta ọgwụ ahụ na akpachara anya mgbe ọ dị ime na mgbe a na-enye ya ara, ebe ọ bụ na diphenhydramine nwere ike ibute nsonaazụ na-adịghị mma maka mmepe nwata. Tupu iburu dọkịta kwesịrị ịtụle uru nne dị n'ihe ize ndụ nye nwa ebu n'afọ, ma ọ bụrụ na ọ dị elu, depụta ọgwụ. Site na inye ara, diphenhydramine na-abanye na mmiri ara, nwere ike ibute nsonaazụ ụmụ amụrụ ọhụrụ ma ọ bụ nwekwuo oke mgbakasị ahụ. N’ebe a na-enye ọgwụ, a na-egbochi ọgwụ.

Diphenhydramine maka ụmụaka

Can nweghị ike iji Diphenhydramine maka ụmụaka na-enweghị ndụmọdụ nke dọkịta ma tụlee okwu nke ọ bụla n'otu n'otu, chọpụta ogo ọrịa ahụ na ngosipụta maka ojiji. Iji ogwu ihe eji eme ihe maka nchịkwa parenteral na injections bụ contraindicated na afọ ruo ọnwa asaa, mbadamba maka nchịkwa ọnụ - ruo afọ isii. Legide usoro ogwu maka nwatakịrị ahụ ka ọ ghara ịdaba na nsogbu ndị ọzọ na-adịghị mma.

Mmanya ndakọrịta

Dabere na nyocha, ọgwụ a na-eme ka mmetụta ethanol dị na usoro ụjọ ahụ dị n'etiti etiti ahụ ike, yabụ, ekwesịrị ịhapụ ihe ọ alcoholụ alcoholụ mmanya na mmanya nwere mmanya ma ọ bụ ọgwụ mgbe niile n'oge ọgwụgwọ ọgwụ. Nchikota nke ogwu na mmanya n’eme ka ndi imeju ghara imebi emebi, mee ka ihe ojoo juo oke ogwu ma mekwaa ya ihe site n’aka ndi metabolites mmanya.

Usoro ire na ebe nchekwa

A na-enye ndenye ọgwụ ọgwụ ebe echekwara ya n'ebe ụmụaka nọ n'ọchịchịrị na-enweghị oke ogo 30 maka afọ ise.

Enwere otutu analogues nke ogwu nwere otu ihe eji eme ihe. N ’ire ere nwekwara ọgwụ ndị ọzọ a na-eji dochie anya ọgwụ, kama ha nwere otu ahụ. Ọgwụ ndị a ma ama:

Diphenhydramine chloride,
Diphenhydramine,
Allergan,
Damedryl
Ibelata ikike
Alledril
Diabenil

Ga - enwe ike ịzụta ndenye ọgwụ na ọgwụ ma ọ bụ n'ụlọ ahịa n'ịntanetị. Ọnụ ego ọgwụ dị na ụdị (mbadamba / ngwọta), oke azụmaahịa na ịta nke ihe arụ ọrụ. Ekwuputara ego maka ọgwụ ọgwụ na pharmacies Moscow na tebụl:

Ampoules 1 ml 10 pcs.

Mbadamba 50 mg 10 pcs.

Veronika, dị afọ 28. Enwere m nsogbu nke ehighị ụra nke ụra, enweghị m ike ịrahụ ụra, ịtụgharị ma tụgharịa ogologo oge, n'ụtụtụ echi ya ana m eteta. Nke a na-emetụta ikike ịrụ ọrụ. Enyi m nyere m ndụmọdụ ka m were mbadamba ụrọ Diphenhydramine n'abalị ugboro ole na ole n'izu. Erubere m isi, afọ ju m. Ọgwụ ahụ ji nwayọ nwayọ, ọ naghị ebute ọgbụgbọ na “ọdịda” dị nkọ n’ụra ihi ụra.

Leonid gbara afọ 38. Oge opupu ihe ubi ọ bụla, m na-amalite ịsụgharị na ụkwara, n'ihi na akwụkwọ ya na-acha, osisi na-ama ifuru. Enwere m nfụkasị, ọ bụ naanị Drophenhydramine nwere ike ịnagide ya. M na-eli ha n'anya m iji belata ọzịza na ọnya, mgbe ụfọdụ, enwere m ike ịbanye na imi m iji wepụ imi na-agba. Ọgwụ dị mma, ọ dịkwa ọnụ ala, ọ dịghị ka ụzọ ọgbara ọhụrụ.

Elizabeth, onye gbara afọ 32. N’ọnwa gara aga, enwere m ọnụnọ ihu mgbu. Ejikọtara ọrụ na kemịkalụ ụlọ, anụ ahụ emeghachiwo. Ogologo oge ka m na-achọ ọgwụgwọ nke nwere ike inye aka, n'ikpeazụ, m kpebiri na mbadamba Diphenhydramine. M na-a themụ ha n’abalị, n’ihi na ọgwụ a na-akpata ụra n’ụbọchị, m na-etekwa ude mmiri na ude. E nwere oganihu, mana obughi ososo dika m choro.

Vitaliy, onye dị afọ 41. Oge izizi otu ọnwa na ọkara gara aga, enwere m nkụchi, m malitere ịrịa ụgbọ ala. Anụrụ m na Diphenhydramine na-arịa ọrịa nke ọma, ekpebiri m ịga ebe ahụ. Ọgwụ emeela ochie - ọ na-eme gị ụra ụra, yabụ na anyị anaghị ekwu maka ịkwọ ụgbọala. M ga-achọ atụtụ ọhụụ nke Diphenhydramine iji kwọọ ụgbọ m.

Mbadamba Diphenhydramine, ntuziaka maka ojiji

30-50 mg site na ugboro atọ n'ụbọchị, ogologo oge nke ọgwụgwọ bụ ụbọchị 10-15.

Ọ bụ ehighị ụra nke ọma E kenyere 50 mg ọkara elekere tupu ụra.

Na postencephalic, idiopathic parkinsonism na mbụ ọgwụ 25 mg ugboro atọ n'ụbọchị, na ụdi usoro a na-eji nwayọọ nwayọọ mụbaa ruo 50 mg 4 ugboro n'ụbọchị.

Ọrịa nkwagharị Kwa awa isii ọ bụla ịchọrọ ị were 25 mg mg nke mbadamba.

Mmekorita

Diphenhydramine na-akwalite ihe nke ọgwụ na egbochi usoro ụjọ. Mgbe ejikọtara ya na psychostimulants edere ihe nduhie edere. MA inhibitors mụbaa ọrụ anticholinergic nke ọgwụ. Na ọgwụgwọ nke nsị, egbu egbu, ọgwụ ahụ na-ebelata arụmọrụ apomorphine.

Diphenhydramine na mmanya

A machibidoro ya ị takeụ ọgwụ ọjọọ. A na-eme ka mmetụta mmanya na-abawanye uru, mmetụta hypnotic na-abawanye, mmerụ ahụ dị ukwuu na ahụ ga-ekwe omume. Enweghị ike ịkọ ihe ga-esi na ya pụta, ọkachasị mgbe ị na-eji nnukwu ogwu. Vodka nwere diphenhydramine nwere ike ịbụ mmanya ikpeazụ n'ime ndụ onye jiri ngwakọta a, ọgwụ a na-egbu egbu nwere ike ịdị obere ma ejiri ya na mmanya.