Ihe kpatara Polydipsia na Diabetes

Ọrịa shuga mellitus (dị ka WHO siri kọwaa) bụ ọnọdụ nke hyperglycemia na-adịghị ala ala nke nwere ike ịmalite n'ihi nsonaazụ nke ọtụtụ ihe na - akpata mkpụrụ ndụ, na - agbakwunye ibe ha. Hyperglycemia nwere ike ịbụ n'ihi enweghị insulin, ma ọ bụ ọtụtụ ihe ndị na-egbochi ọrụ ya.

Etiology

A na - ekekọta insulin site na sel-sel nke islet ngwa nke pancreas. Ihe ndị na - eme ka insulin rụọ ọrụ bụ preproinsulin na proinsulin. Site na nke ikpeazụ, mgbe C-peptide kpochapụrụ, a na-emepụta insulin, nke a na-abanye n'ime ọbara. Insulin bụ homonụ protein nke na-ahụkarị ahụ mmadụ mgbe ya na ndị na-anabata mkpụrụ ndụ na-emekọ ihe.

A na-ahụ ihe banyere mkpụrụ ndụ insulin na mkpụmkpụ mkpụmkpụ nke chromosome 11, ma ihe nnabata nke insulin na-enweta insulin dị na chromosome 19. Imebi ihe nzuzo, njikọta ma ọ bụ ijikọ insulin na ndị na-anabata ya na-eduga na mmepe nke ọrịa mellitus. Ọ na-akpatakarị nsogbu ndị a na mgbanwe maka mkpụrụ ndụ ihe nketa. Site na mmụba mkpụrụ ndụ ihe nketa, dịka iwu, hyperinsulinism na-apụta.

N'ime ụdị ọrịa shuga 2, ihe na-akpata ọgba aghara nke carbohydrate bụ mbelata njikọ nke insulin na-anabata ndị na-anabata ya ma belata ọnụ ọgụgụ nke ndị na-anabata ya. N'ime ụdị shuga 1, ihe kpatara ụkọ insulin bụ mbelata na njikọ nke insulin n'ihi insulin na-aga n'ihu. Ntọala nke insulin bụ mbibi nke mkpụrụ ndụ β, nke ọ kpatara site na ọrịa nje ma ọ bụ mmebi nke onwe ya.

Jenetik na immunology nke ọrịa shuga

Ihe nketa nke ụdị ọrịa shuga 1 bụ okpukpu abụọ. N'ime ọtụtụ ndị ọrịa nwere ụdị shuga 1, enwere ike ịchọpụta njikọta njikọta dị iche iche nke ụdị ọgwụ mgbochi nke usoro histocompatibility nke klaasị II HLA-DQ na HLA-DR. Ihe nketa nke ụdị ọrịa shuga 2 bụ akara akpaaka. Mgbe ị na-achọpụta ụdị ọrịa shuga 1 na mbido ọrịa ahụ, mgbe ọ ka nọ na ọkwa ahụ, a ga - achọpụta mkpụrụ ndụ nke mkpụrụ ndụ β-sel na insulin. A na-ahụta ọdịdị nke ọgwụ mgbochi ogologo oge tupu ngosipụta nke ọrịa shuga.

Ihe nrịbama maka oria 1

Ihe omumu: HLA DR3, DR4 na DQ

Immunological: autoantibodies iji glutamate decarboxylase (GAD), insulin (IAA) na alfa-cell antigen (ICA), na-edozi mmezi mgbochi ọgwụ plasma.

Pathogenesis

Ọrịa pathogenesis nke ọrịa mellitus dị mgbagwoju anya, mana ọ dabere na ezughi oke insulin nke ezughi oke. Ọ bụ ụkọ erughi ihe na-akpata site na ịba ụba nke homonụ ndị na-ahụ maka mmiri, ndị na-emegide insulin nke na-abụghị homonụ, ma ọ bụ nwee mmetụta nke ndị na-anabata insulin. Insulin bụ anabolic homonụ, i.e. n'okpuru ọnọdụ nkịtị, ọ na - enye aka na nchịkọta nke glucose n'ụdị glycogen, na - eme ka mgbakwunye protein dị elu, na - akpali glycogenesis, na - eduga n'ịchịkọta ike n'ụdị nke mkpụrụ ndụ ATP. N'ihi ya, ọ dị mfe iche n'echiche na enweghị ọgwụ insulin usoro nke protein catabolism na-abawanye, ụlọ ahịa glycogen na-agbada, a na-akpali lipolysis, ATP na-enwebelata, i.e. enwere nsogbu ọghọm.

Mmụba na glucose ọbara n'ihi glycogenolysis na neoglucogenesis na-eduga n'ịba ụba osmolarity plasma, nke na-eduga ná mmebi nke metabolism mmiri na osmotic diuresis.

Lipolysis na - abawanye na enweghị glycogen na imeju na --eme ka ịbawanye ụba nke anụ ahụ ketone, nke na - esote mmepe nke ketosis ketoacidosis. Ya mere, acid-base stere ahu na-enye nsogbu. Enweghị ume ike na-eduga ná ụkọ nke potassium na anụ ahụ.

Ọrịa shuga na-esokwa nsogbu nke ụdị metabolism niile.

Nhazi ọkwa nke ọrịa shuga mellitus (WHO, 1999)

1dị shuga 1 nke ọrịa mellitus (mbibi β-sel, na-eduga na ụkọ insulin zuru oke)

Diabetesdị shuga abụọ nke ọrịa mellitus (site na iguzogide insulin nke ukwuu na ụkọ insulin ruo na ntụpọ mmerụ ahụ nke nwere insulin na-enweghị ma ọ bụ na-enweghị ya

Specificdị ọrịa shuga ndị ọzọ akọwapụtara

Mkpụrụ ndụ ihe nketa emepụtara na-arụ ọrụ sel

Ọkpụkpụ mkpụrụ ndụ ihe nketa nwere ọrụ insulin

Ọrịa nke ọrịa exocrine

Ọgwụ ma ọ bụ Chemical Diabetes

Diabetesdị ọrịa shuga na-alụ ọgụ na-enweghị atụ

Usoro mkpụrụ ndụ ihe nketa ndị ọzọ na-ejikọta ya na ọrịa shuga oge ụfọdụ

Afọ ụkwara ume ọkụ

Diagnostics

Mellitus nke pụtara ọrịa ma ọ bụ nke na-apụta ìhè nwere ụlọ ọgwụ akọwapụtara nke ọma: polydipsia, polyuria, felata. N'oge ule ọbara, achọpụtara mmụba nke glucose na ya, na mmamịrị - glucosuria na aceturia. Y’oburu na enweghi ihe mgbaàmà nke hyperglycemia ala ala, mana mmụba na-achọpụta glucose na mberede n’inyocha shuga ọbara, na nke a, a na-eme nnwale nnabata glucose iji chọpụta nchoputa ahụ ma ọ bụ wezuga ọrịa shuga.

Nnyocha nnabata glucose nwoke:
Tupu nnwale ahụ, ọ dị mkpa ịdebere nri nkịtị na-enweghị mgbochi mmachi nke carbohydrates nwata ahụ n’ime ụbọchị atọ. A na-eme nnwale ahụ n'ụtụtụ na afọ efu. Ejiri glucose na ọnụọgụ 1.75 g / n'arọ nke ezigbo ịdị arọ, mana ọ bụghị ihe karịrị 75 g. A na-eme nnwale shuga n’afọ na-enweghị ihe dị ka nkeji 120 mgbe ị nwesịrị glucose.

Usoro nyocha maka ọrịa shuga na ọrịa ndị ọzọ metabolism metabolism (WHO, 1999)

Ta ahụ glucose, mmol / l (mg /%)

Na b / w 2 awa mgbe GTT gasịrị

Ma ọ bụ h / s elekere 2 ka nke GTT gasịrị

Ma ọ bụ 2 awa mgbe nri gasịrị (postprandial glycemia)

▪ ma ọ bụ mkpebi siri ike nke glycemia n'oge ọ bụla n'ụbọchị, n'agbanyeghị oge iri nri

Nnukwu nnabata glucose

Na b / w 2 awa mgbe GTT gasịrị

Glycemia na-ebu ọnụ

Oria di iche

A na-achọpụta nchọpụta dị iche site na akara ngosipụta a na - esochi ọrịa shuga: polydipsia na polyuria. A na-ahụta ụdị ọrịa ndị a na ọrịa insipidus - ọrịa shuga insipidus, yana n'ụdị mmalite nke ọdịda akwara na-adịghị ala ala, bụ nke e ji mara polydipsia na polyuria.

Ihe nrịanrịa oria bụ ihe e jiri mara glucosuria nke otu ogo ma ọ bụ nke ọzọ, njiri mara nke proximal tubulopathies: De Tony-Debre-Fanconi syndrome, ọrịa shuga.

Acetonuria na - eso ọnọdụ niile mara agụụ agụụ maka anụ ahụ ogologo oge, ọ na - enwekwa nnukwu mbibi imeju.

Igolata oke ibu ogologo oge bu ihe eji mara ndi endocrinopathies dika inye oria ojoo, hypocorticism.

Ọrịa shuga na-eme ngwa ngwa

Ọrịa mamịrị ketoacidosis (DKA II-III)
Nsogbu kachasị njọ na-arịa ọrịa shuga bụ ketoacidosis nke na-arịa ọrịa shuga. Egosiputa onodu a site na njiko insulin zuru oke na nke idi nso, nke ikpeazu nke a na-ebute site na mmụba nke anụ ahụ nke ma ndị na - alụ ọlụ ikuku na - achọghị ịba.

Ejiri Ketoacidosis mara:

hyperglycemia dị elu na osmotic diuresis na

mbelata nke ukwuu na akụrụngwa nke ọbara n'ihi

mkpochapu nke bicarbonates, na - eweta mgbanwe na steeti acid-uzo na uzo nke metabolic acidosis

Uto nke ọrịa metabolic siri ike na ụkọ insulin na-achịkwaghị achịkwa na-eduga na hypovolemia, nkwupụta nke ike nke potassium na anụ ahụ, yana nchịkọta nke β-hydroxybutyric acid na sistemụ akwara. N’ihi nke a, a ga-amata mgbaàmà nke ajọ ọrịa akwara mkpali, nsogbu akwara amụkwo maka ịda mba, nsogbu ịmara ruo coma, na nsogbu ahụike.

N'ọnọdụ ndị a na-adịghị ahụkebe, na ụmụaka enwere:

njigide sodium

Lactatecedemic coma bụ rama coma n'ime ụmụaka, ọ na - abụkarị na mmepe ya enwere hypoxia anụ ahụ dị ukwuu na mkpokọta lactate n'ime ọbara.

Ọrịa mamịrị ketoacidosis

Imezi ụkọ insulin

Tupu o gwọọ ọgwụ, onye ọrịa ahụ kpuchiri okpomoku, a na-etinye tube nasogastric, catheter n'ime eriri afo.

A na-agbakọ ọnya mmiri ahụ dabere na afọ:

n'ime ụmụaka afọ atọ mbụ nke ndụ - 150-200 ml / n'arọ ibu / ụbọchị, dabere na ogo nke akpịrị

n'ime ụmụaka toro eto - 3-4 l / m2 / ụbọchị

N'ime nkeji iri atọ mbụ nke iwebata 1/10 kwa ụbọchị. N'ime awa 6 mbụ, 1/3 nke ọgwụ kwa ụbọchị, n'ime elekere isii na-esote - 1/4 nke usoro kwa ụbọchị, wee kwee.

Ọ dị mma iji infusomat bufee mmiri mmiri, ma ọ bụrụ na ọ nọghị, jiri nwayọ gbakọọ ọnụọgụ nke nkeji kwa nkeji. A na - eji sodium chloride 0.9% mee ihe dịka mmalite. Ekwesịrị ijizi saline gafee elekere abụọ. Mgbe ahụ ọ dị mkpa ka ịgbanwee gluu 10% glucose na ngwakọta Ringer na oke nke 1: 1. A na-ewe mmiri niile ka a na-awụnye ya intravenally mgbe ọ na-adị 37 Celsius. ọ bụrụ na nwatakịrị ahụ nwere nkụda mmụọ, anyị na-eji 10% albumin na-edozi tupu ịmalite nchịkwa nke kristal na ọnụego 5 ml / n'arọ, ma ọ bụghị karịa 100 ml, n'ihi na colloids ka idowe mmiri na mmiri.

Usoro ọgwụgwọ insulin

A na - eji insulin eme ihe dị mkpụmkpụ. Ọ kachasị mma ịnye insulin site na lineamate na azum 10% albumin, ọ bụrụ na enweghi lineomat, insulin na-agbanye jet kwa awa. Usoro izipu insulin bụ 0.2 U / n'arọ, mgbe nke a gasị, elekere 0.1 U / kg / awa. Site n’ibelata shuga dị n’ọbara ruo 14-16 mmol / l, ọ̀tụ̀tụ̀ insulin na-agbadaru ruo 0.05 U / kg / awa. Site na mbelata ọbara shuga ruo 11 mmol / L, anyị na-agbanwe gaa na nchịkwa insulin na-adị ala elekere isii ọ bụla. Mkpa insulin mgbe ewepụrụ ya na mmiri bụ 1-2 nkeji / n'arọ / ụbọchị.
Ntị! Ọnụego mbelata glucose ọbara ekwesịghị gafere 5 mmol / awa! Ma ọ bụghị ya, mmepe nke ụbụrụ ga - ekwe omume.

Ndozi Acidosis

Iji dozie acidosis, a na-eji mmiri soda 4% soda nke 4 ml / n'arọ a na-ekpo ọkụ, nke a kwadebere ọhụrụ. Ọ bụrụ na a ga - ekpebisi ike na BE, yabụ, ọgwụ bicarbonate bụ 0.3-BE x dị nwatakịrị na kilogram.
A na-eme mgbazi Acidosis na awa 3-4 nke ọgwụgwọ ọ bụghị na mbụ, n'ihi na-eme ka insulin na-eme ihe megide ụzụ nke ịmịkụkụ nke ọma na-enwe njikọ ketoacidosis.
Ihe kpatara iwebata soda bụ:

marbling nke anụ ahụ

oké ume iku ume

Na ọgwụgwọ nke ọrịa mamịrị acidosis, a na-agbanye obere heparin ka ọ bụrụ 100 / kilogram / ụbọchị na 4 na injections. Ọ bụrụ na nwatakịrị na-eji ọnọdụ okpomọkụ abịa, a na-enye ọgwụ mgbochi oke ngwa ngwa. Ọ bụrụ na nwatakịrị ahụ ji akara mmalite nke ketoacidosis (DKAI), i.e. n'agbanyeghị metabolos acidosis, nke mkpesa dyspeptik (nke ọgbụgbọ, vomiting), mgbu, iku ume miri emi, mana nsụhọ dị mkpa:

Jiri mmanu 2% dochie afo.

Tinye akwa nhicha, mgbe ahụ ọgwụ enema nwere mmiri ọkụ nke 2% soda na olu nke 150-200 ml.

Iji mepụta ọgwụ mgbochi, nke gụnyere albumin, ihe ọmụmụ physiological, ma ọ bụrụ na ọkwa glucose agaghị agafe 14-16 mmol / l, mgbe ahụ, a na-eji ihe ngwọta nke glucose 10% na Ringer mee ihe na 1: 1. A na-agbakọ usoro ọgwụgwọ infusion na nke a maka awa 2-3 na-adabere n'ihe ndị a chọrọ kwa ụbọchị, n'ihi na-emecha, inwere ike ịgbanwee rehydration ọnụ.

A na-eme insulin ọgwụ na ọnụego 0.1 U / kg / h, mgbe ọkwa glucose bụ 14-16 mmol / L, dose ahụ bụ 0.05 U / kg / h yana n'ọkwa glucose nke 11 mmol / L anyị na-agbanye na nchịkwa subcutaneous.

Usoro nke ịdu nwata mgbe ọ kwụsịrị ketoacidosis

Maka ụbọchị 3 - nri Nke 5 na-enweghị abụba, mgbe ahụ okpokoro 9.

Na-a plentyụ mmiri dị ukwuu, gụnyere mmiri alkaline (mmiri ịnweta, ihe ngwọta nke 2% soda), ihe ọicesụ juụ nwere agba odo-acha ọbara ọbara, n'ihi ha nwere potassium nke ukwuu.

Site n'ọnụ, 4% potassium chloride ngwọta, 1 dess.-1 tebụl. ngaji 4 ugboro n'ụbọchị maka ụbọchị 7-10, n'ihi na mgbazi nke hypokalisthia bụ ogologo oge.

Edere insulin na inje 5 n'ime usoro ndị a: n'elekere isii nke ụtụtụ, wee gafee ụtụtụ, nri ehihie, nri abalị na n'abalị. Usoro izizi bụ nkeji 1-2, nke ikpeazụ bụ 2-6 nkeji, na ọkara mbụ nke ụbọchị - 2/3 nke usoro kwa ụbọchị. Bọchị kwa ụbọchị ya na ọnụọgụ mkpochapụ si ketoacidosis, nke na-abụkarị ogo 1 U / n'arọ. A na-eme ụdị ọgwụ insulin ahụ ruo ụbọchị 2-3, mgbe nke ahụ gasịrị, agafere nwata ahụ na ọgwụgwọ bolus.

Rịba ama Ọ bụrụ na nwatakịrị nwere ketoacidosis nwere uto okpomoku, a na-enye ọgwụ mgbochi oke. Na njikọta ọrịa hemostasis kpatara hypovolemia na metabolic acidosis, a na-atụgharị heparin kwa ụbọchị nke 100 U / n'arọ nke ịdị arọ ahụ maka igbochi mgbasa nke ọrịa coagulation mgbasa. A na-ekesa ọgwụ ahụ ihe karịrị 4 injections, a na-agwọ ọgwụ n'okpuru njikwa coagulogram.

Ọrịa mamịrị
Nri
A na-ekpebi mkpo calorie site na afọ nwata ahụ, yana oke ibu ma ọ bụ enweghị ibu. A na-eme atụmatụ ahụ dịka usoro si kwuo: 1000 kcal + 100 • n (n bụ ọnụọgụ afọ tọrọ otu afọ). Site na oke buru ibu, kalori na-agbada site na 10 - 15%, yana ụkọ, ọ na-abawanye site na 10 - 15%. Egosiputa ihe kalori kwa ubochi nke nwa n’otu n’afọ n’agbal bya na udiri nri ma na-aghazikwa nri nke nwatakiri nwere ahụ ike. Ekwesịrị ịkọwapụta na nri ahụ nwere carbohydrates 50-60%, protein 15-20% na abụba 30-35%.

A na-agbakọ Carbohydrates na nkeji achịcha - 1 XE = 10 - 12 grams nke carbohydrate. N ’nri, ekwesịrị inwe nri zuru ezu, nri ndị na-enye ihe ndị dị n’ahụ́ kwesịrị inwe obere ihe glycemic. Ekwesiri icheta na ike nke 1 gr. Protein na 1 gram nke carbohydrates = 4 kcal, na 1 gram nke abụba = 9 kcal. A na-ewepụ carbohydrates ngwa ngwa ka nri na-edozi ahụ. Enwere ike iji aspartame aspartame, ọ bụghị karịa mbadamba 3 kwa ụbọchị. Abụba abụba kwesịrị ịnọchite anya abụba anụ 50% na akwukwo nri 50%. Onu ogugu nri di iche iche n’adabere na umu aka ya. E.P.Kasatkina na-enye ụmụaka nri nri 2

Youngmụaka na-eto eto na-erubeghị afọ 1, gbakọọ agbakọ nri na ọnụ ọgụgụ nri, gụnyere nri agbakwunye, ka a na-ebu site n'ụdị inye nri (agbari, agwakọta, eke). Okwesiri iburu n'uche na odi nma ka inye ya ara rue 1.5. Dabere na data anyị, ndị nne na nna nwere nnukwu mmụọ maka ụdị nri.

Ofdị insulin
Ultrashort analogues nke insulin - Novorapid, Humalog (Nova-Nordisk, Ellie-Lily fir).
Short - Actrapid, Humulin R.

Ihe omume etiti - Protafan, Humulin N (Nova-Nordisk, Elli-Lily fir).
Ka ọ dị ugbu a, omume onye na-arịa ọrịa diabetologist gụnyere insulins ndị na - adịkarịghị ogologo - Detemir (Nova-Nordisk firm), Lantus (firm Aventis firm).

A na - eji ọgwụ ndị a eme ihe dika insulins basal yana nchịkwa bolus nke insulin ultrashort.

Ọganihu kachasị ọhụrụ na usoro ọgwụgwọ insulin bụ ntinye nke nfuli insulin (nfuli), nke na-enye ntụzi kwa ụbọchị nke glycemia na nfuli ndị a site na iji naanị insulins dị mkpụmkpụ.

Emeela ka insulin na-eme nwa obere nwa na omume ndị dibịa; enweghị data ọ bụla na ojiji ụmụaka.

Usoro ọgwụgwọ insulin
A na-eji usoro ọgwụgwọ ọgwụgwọ siri ike eme ihe ugbu a, nke na-agụnye n'otu oge ahụ glycemia na-eji mpempe ule nyocha ma ọ bụ glucometer na mmezi insulin. Ka ọ dị ugbu a, ọ bụ naanị insulins ndị nwere ihe omumu sitere na mkpụrụ ndụ ihe eji eme ihe na-eji ụmụaka, bụ ndị ultrashort (awa 2), mkpụmkpụ (awa 6) na etiti (awa 16). A na - ahọpụta usoro nhazi nke insulin insulin site na endocrinologist na - eburu n'uche njirimara nke nwatakịrị a, a na - eji ọnọdụ bolus bụ isi, i.e.N'ehihie, na ntinye insulin basal (ihe dị n'etiti), a na-enye insulin ahụ na-adị mkpụmkpụ tupu nri buru ibu. Enwere ike inye insulin etiti oge ọrụ site na ugboro 1 ruo 4 kwa ụbọchị, insulin na-adị mkpụmkpụ - site na ugboro anọ ruo ugboro isii kwa ụbọchị, ọ bụ ọkachamara na-ekpebi ihe niile.

Uru nke ultrashort insulin

A na-enye ha ngwa ngwa tupu nri, ọ dịghị mkpa ichere na minit 30 ruo 40 dị ka mgbe ị na-ede akwụkwọ insulins dị mkpụmkpụ, mgbe edepụtara ha, ihe ize ndụ nke hypoglycemia na-ebelata, nwatakịrị ahụ na-enweta nnwere onwe na oge nri. Anyị ejirila obere mkpirisi mkpirisi iji mee ndị na-eto eto nwere nnukwu mkpali na njikwa glycemic na njide onwe onye. A na-ekpebi ọgwụ insulin kwa ụbọchị na-ekpebi n'otu n'otu, ọ na-abụkarị n'afọ mbụ nke ọrịa ọ bụ 0,5 U / n'arọ ahụ, mgbe afọ 5 gasịrị - 1 U / n'arọ ahụ. N'ime ụmụaka, a na-agbakọọ doses na-eburu n'uche glycemia ma na-abawanye n’arụ ahụ, nke chọrọ mgbatịkwu ugboro ugboro, mana agbanyeghị na ha ekwesịghị gafere 0.25 - 0,5 U / n'arọ nke ịdị ahụ ya. N’ime ndị nọ n’oge uto, n’ihi mmụba nke insulin, mkpa nke insulin nwere ike ịdị site n’arụ 1 ruo 2 U / n'arọ.

Ọgwụ insulin overdose Syndrome

N'ihe banyere insulin ọgwụ ezughi oke, mmepe nke mmetụta Somogy ga-ekwe omume. A na - ahụta mmetụta a mgbe ị ofụfere insulin, mgbe ọ na - aza hypoglycemia nke ehihie, mwepụta nke homonụ nke mgbochi (glucogon, cortisol, adrenaline, hormone) na - eme, nke na - ebute mmụba na shuga ọbara ọbara.

Nleba anya nke ogwu:

Iwe na ụtụtụ

N'ọtụtụ akụkụ hypoglycemia dị ukwuu, ihe kpatara ya nwere ike ịbụ nguzogide insulin n'ụtụtụ (n'ụtụtụ awa site na 5 ruo 9 n'ụtụtụ), ihe a na-akpọ Down phenomon, bụ ihe ịtụ n'anya nke chi ọbụbọ. Ọ na - akpata ya na nzuzo site na mmiri ọgwụ mgbochi na - egbochi homonụ.

Maka nyocha, ọ dị mkpa iji chọpụta shuga na 3 nke ụtụtụ. Ọ bụrụ na n’elekere 3 nke ụtụtụ shuga bụ ihe dị mma, ma n'ụtụtụ, hyperglycemia bụ Down onu. N'okwu a, ọ ka mma yigharịtụ ntụtụ insulin nke etiti.

Ọgwụ nke ụdị shuga 2 na ọrịa shuga MODY

Iji kwado nchoputa, umu aka tupu mgbe emechara batrị na-eduzi omumu ihe banyere IRI ma obu C-peptide, nke ikpeazu kariri ihe omuma. A na-enyocha ọkwa nke hemoglobin glycated. Ugbu a, ọgwụgwọ nke MODY-ọrịa shuga na-adabere n'ụdị ya, i.e. Enwere ike iji biguanides (metformin) na insulin mee ihe.

Egwuregwu na mmega ahụ
Imega ahụ mgbe niile, zuru ezu na-eme ka insulin mara ma na -ebelata mkpa ọ dị. Ọtụtụ mgbe, ndị mmadụ na-abanye egwuregwu maka oge na-erughị otu elekere mgbe ha risịrị nri. Ọ dị mma inyocha shuga dị n'ọbara tupu oge mgbatị ahụ, yana nke ga - enye gị ohere ịgbanwegharị insulin. A nabataghị nwatakịrị ahụ ịme egwuregwu na obere glycemia dị ala. N'okwu nke mbụ, nwatakịrị ahụ kwesịrị iri 1-2 XE tupu klaasị, na nke abụọ, ụgwọ maka metabolism metabolism dị mkpa, wee banye n'egwuregwu. Ogologo oge nke ibu ahụ kwesịrị ịbụ nkeji 30-40. Ọ bụrụ na egwuregwu ahụ mechie site na nri abalị, ịkwesịrị iji nkeji abụọ belata ọgwụ mgbede insulin nke etiti iji gbochie hypoglycemia nke ehihie.

Ọzụzụ
Ebumnuche nke ọzụzụ ahụ bụ ime ka ndị nne na nna na ụmụ ha mara banyere ọrịa ahụ. A na-akpọbata ụmụaka na ndị nne na nna n'ime usoro iji hazie njide onwe ha nke ọma, ma, ọ bụrụ na ọ dị mkpa, na-aza nke ọma maka mgbanwe mgbanwe enwere ike na steeti. Ọ bụ dọkịta, nọọsụ na-abụ onye nkụzi nke oflọ Akwụkwọ Ọrịa shuga duziri ọzụzụ a. N'oge ọzụzụ, a na-ewere ọnọdụ dị mkpa site na nkwadebe mmụọ nke nwatakịrị na ndị nne na nna maka nsogbu a na-eme, nke a na-emekọ ya na onye ọkà mmụta uche.

Ebumnuche nke ọgwụgwọ na njikwa

Usoro ọgwụgwọ ọrịa shuga na-agbazi iji gbochie ọrịa a, mgbochi nke ibute ọrịa (vaskụla) nwayọ.

Ebumnuche bụ isi: inye nwatakịrị ahụ ahụ tozuru oke anụ ahụ na nke uche, usoro mmụta mmekọrịta ya na-aga nke ọma.

Iji mezuo ebumnuche a, ụgwọ zuru oke nke metabolism metabolism, i.e. normoglycemia na aglucosuria, ọdịnaya haemoglobin nkịtị glycosylated. Njikwa na njide onwe onye na nke a, nke na-atụ aro: ịgbakọ izu nke nri, njikwa n'oge mgbatị anụ ahụ oge niile.

Ezigbo ya bụ ọmụmụ gbasara ọbara ọgbụgba na-glycosylated otu ugboro n'ime ọnwa 2-3 ọ bụla. N'ime usoro ọgwụgwọ, omumu banyere ịdị omimi nke ịdị arọ na ịdị elu.

Ọ bụrụ na ọrịa shuga na-adị ihe karịrị afọ 5, nlezianya nyochaa ọbara mgbali, urinalysis maka albuminuria, oge nyocha nke ndị ọrịa n'ụlọ ọgwụ nyocha vaskụla maka anya mkpụrụ ọgwụ maka ịchọpụta retinopathy dị mkpa. Ugboro abụọ n’afọ, ọ ga-enyocha nwa ahụ site n’aka dọkịta ezé na dọkịta ENT.

Ntuziaka maka ịkwụghachi metabolism metabolism n'ụdị ọrịa shuga m

Nnyocha onwe nke glucose n'ọbara, mmol / l (mg%)

Glycemia tupu ụra

Hypoglycemia

Hypoglycemia na-etolite ma ọ bụrụ na ịba insulin na-eme karịa nke carbohydrates na-enye nri. Ihe ọzọ kpatara hypoglycemia bụ ọgwụ insulinal insulin mgbe ị na-ewepụ onye ọrịa na ketoacidosis na / ma ọ bụ oke ego glucose parenteral ezughi oke.
Hypoglycemia na-esochi ọrịa ndị a:

Odide na-ahụ ụzọ

Ihe mgbaàmà ndị a niile bụ ngosipụta nke neurohypoglycemia na mmeghachi omume ọmịiko-adrenal na nzaghachi maka mbelata glucose ọbara. Ọzọkwa, ụmụaka toro eto nwere agụụ, ma obere, na Kama nke ahụ, ha anaghị eri nri.

Ọ bụrụ na enyeghị aka, hypoglycemic coma nwere ike ịmalite, i.e. mwepu nke nsụhọ na - akpata site na metabolism na - eme ka ọ daa ọrụ na etiti akwara. Site na coma miri emi, akụkụ ụbụrụ na-apụta, nke na-egosipụta onwe ya n'ụdị nkwarụ na-asọ oyi.

Site na hypoglycemia dị nro, ịkwesịrị iri achịcha ma ọ bụ mkpụrụ osisi, nwere nnukwu hypoglycemia, shuga, sweets, jam, jam. Site na mwepu uche, a na-agbanye mgbanye glucose 20 ruo 40% na akwara n'ime ego 20.0 ruo 40.0. Ọ bụrụ na enweghị mmetụta ọ bụla, enwere ike ịmeghachi ya. Ọ bụrụ na hypoglycemia na-etolite n'ụlọ ma ọ bụ n'ụlọ akwụkwọ, ọ bụrụkwa na onye ahụ amaghị nke ọma, ọ dị mkpa inye 1 mg nke glucagon n'ime / akwara tupu dọkịta abịarute (Glucagen, ụlọ ọrụ Novo-Nordisk).

Dọkịta aghụghọ na ọnọdụ pụrụ iche

Ọrịa
N'oge ọrịa, mkpa insulin na-abawanye, agbanyeghị, agụụ nwere ike gbanwee, na-agbadata mgbe niile. Ya mere, n'oge ọrịa, ọ dị mkpa iji nlezianya nyochaa glucose ọbara, yana glucose na acetone mmamịrị. N'ihe banyere hyperglycemia, enwere ike ịbawanye ụba nke insulin n'ihi insulin dị mkpụmkpụ. N'okwu a, mgbanwe onwonye nwayọ nwayọ: ọ bụrụ na nwatakịrị ahụ na-enweta ihe ruru 20 PIECES / ụbọchị - gbakwunye PieCES 2, ma ọ bụrụ na enweta karịa 20 PIECES / ụbọchị - 4 PIECES. Mana n’ozuzu, mmụba kwa ụbọchị n’oge ọrịa ekwesịghị ịkarị karịa 20% nke ọgwụ mbụ.
Ọ bụrụ na a na-ebelata agụụ mgbe ọrịa na-aga, mgbe ahụ, a na-ebelata ọgwụ ahụ site na 2 ma ọ bụ 4 PIECES dabere na nke mbido, ma ọ bụ mgbanwe ya na ụzọ mbelata na-adabere na glucose ọbara na hypoglycemia nwere ike.

Dozọ ndị dọkịta si eme ka ọrịa mellitus na-arịwanye elu: ọdịdị nke ihe mgbaàmà nke polydipsia, polyuria.
N'okwu a, ọ dị mkpa ịbawanye ọgwụ kwa ụbọchị nke insulin n'ihi nke dị mkpụmkpụ site na 10-20% nke ọgwụ kwa ụbọchị, na-agbakwunye ọnụ ọgụgụ achọrọ maka nkeji tupu nri. Ekwesịrị inye otu ụdị ahụ kwa ụbọchị maka ụbọchị 2-3 iji kwụọ ụgwọ metabolism. N'oge a, ọ dị mkpa ịchọpụta ihe kpatara asị ahụ ka ekweghị ka ọ gaa n'ihu.

Ọgwụ insulin ịwa ahụ

Obere arụmọrụ rụrụ n'okpuru anesthesia mpaghara. Usoro nri na-emebu na usoro ọgwụgwọ insulin. Ọ bụ ihe amamihe dị na ya ịme ọrụ ahụ n'ụtụtụ.

Operationsrụ ọrụ dị mkpirikpi n’azu azịza. N'ụbọchị ịwa ahụ, ọgwụ were 50% nke ụbọchị insulin na-eme ihe dị mkpirikpi nke onye ọrịa natara na-abata n'ụzọ. N'otu oge ahụ, a na-amalite glucose 5% intravenously mmiri, na-abụkarị na ọnụego kwekọrọ na mmiri ọmụmụ kwa ụbọchị chọrọ - 60 ml / kg / ụbọchị. 7.5% ngwọta nke potassium chloride na-agbakwunye na glucose na ọnụego 2 ml / kg / ụbọchị. A na-enyocha ọbara shuga n'oge ịwa ahụ, ka emesịrị ya, ma emesịa ọ bụla awa 2 kwa ụbọchị. Surgerywa ahụ, a na-ahụ insulin subcutaneously kwa awa 6 na ọnụego nke 0.25 U / n'arọ ahụ.
Ozugbo enwere ike inye ya nri, kwụsị infusion ma gbanwee gaa na usoro ọgwụgwọ insulin dị mbụ. A na-ejikarị ọgwụgwọ ọgwụ mgbochi na-arụ ọrụ 12, ọ dịkarịa ala awa 24.

Surgerywa ahụ ogologo oge n'okpuru ihe mgbochi ma ọ bụ ịwa ahụ mberede maka ebumnuche ahụike.
Ekwesịrị ịgwọ ọrịa infusion na ndabere nke mmiri mmiri ụbọchị chọrọ: glucose 5% na mgbakwunye nke 1-3 ml / n'arọ ibu / ụbọchị 7.5% nke potassium chloride.
Dabere na glycemia, a na-eduzi insulin n'ụzọ ọbara na glucose. Ọ bụrụ na shuga dị n'ọbara bụ 8.3 mmol / l, mgbe ahụ, a na-ahụ insulin na ọnụego 1 IU kwa 4 gram nke glucose akọrọ, site na 8.3 - 11.1 mmol / l - 1 IU - 3 grams nke glucose akọrọ, karịa 11.1 mmol. / l - 1 ED - 2 g.
Mgbe ọ rụsịrị ọrụ ahụ, a na-aga n'ihu na-enye glucose ọbara ruo mgbe ọ ga-eri ihe ma drinkụọ ihe ọ ,ụ ,ụ, a na-ahụkwa insulin na ogo 0.25 U / n'arọ ahụ kwa awa 6 s / cutaneous.

Ihe ndi n’egosi oria shuga n’aru umuaka

N'ọtụtụ ụmụaka, ka izu abụọ na anọ gachara site na oge ịtọlite ​​ọrịa ahụ na usoro ọgwụgwọ kwesịrị ekwesị, ọrịa ahụ ga-amalite ma nwetakwa mgbaghara ga-ekwe omume, mgbe ọ dị belata insulin nke ukwuu. Oge a ga - anọ ọtụtụ izu ma ọ bụ ọnwa. Mgbe ahụ, mkpa insulin na-ebili ọzọ wee rute na afọ 3-5 site na mmalite nke ọrịa 0.8-1 U / n'arọ ibu. N'oge uto, ubara homonụ na-abawanye, uto uto na-amụba ma na-abawanye uru ahụ. Ihe e ji mara ọrịa shuga n'oge a bụ ịrụ ọrụ nke ukwuu ma chọọ nlezianya anya. Mgbe afọ uto, ọrịa shuga amalitewo kwụsie ike. Enwere ike ịbawanye ọgwụ insulin n'oge uto, site na 1 ruo 2 nkeji / n'arọ ibu / ụbọchị. Ekwesịrị icheta na ọrịa shuga na-abụkarị mpụta polyendocrinopathies. Mgbe nke a gasịrị, ụmụaka nwere ike ịmalite ọrịa oria nke gland endocrine ndị ọzọ, bụ nke bụ azụ gland bara ụba.
Compensationgwọ ọrịa na-adịghị mma nke ọrịa shuga na-eduga n'ịmebi ụdị metabolism na protein niile, nke n'aka nke ya na ibelata nchekwa na enweghị nchekwa. N'ihi ya, ugboro ugboro nke tolitere ọnya ọrịa nke anụ ahụ na mucous membranes n'ụdị pyoderma na ọrịa fungal, usoro ọgwụgwọ ahụ siri ike.

Ọrịa shuga na-eji nwayọọ nwayọọ amalite

Ha dabere na nsogbu vaskụla na ụmụ - microangiopathies, mmepe nke dabere na njiri mkpụrụ ndụ ihe nketa nke nwatakịrị na ụgwọ ọrụ nke carbohydrate metabolism. Ọtụtụ mgbe microangiopathies na-etolite mgbe afọ ise gasịrị site na mmalite nke ọrịa.

Nehropathy na-arịa ọrịa shuga
Ka oge na-aga, ihe dị ka 1/3 ndị ọrịa nwere ụdị 1 na-arịa ọrịa akwara na-adịghị ala ala, bụ nke sitere na ọrịa mamịrị glomerulosclerosis. Site na ụgwọ ụgwọ ọrịa shuga dị mma, mmalite nke ọdịda akwara na-adịghị ala ala nwere ike igbu oge. A na-eme nchọpụta preclinical nke ọrịa mamịrị nephropathy site na iji nnwale microalbuminuria. Etechọpụta microalbuminuria chọrọ imechi njide onwe onye, ​​njikwa glycemia, nlebara anya ọbara ọgbụgba mgbe niile. ACE inhibitors (Monopril, Diroton, Enalapril, Renitek) ma ọ bụ angiotensin II receptor inhibitors (Cazaar) ejirila ọgwụ ọgwụgwọ n'oge a. Site na mgbe etolitela kọri ọtọ nke ọrịa mamịrị nephropathy, ileba anya na nwata ahụ ga-agbacha nke ọma.

Ọrịa mamịrị retinopathy
Ejiri ọrịa retinopathy nke ọrịa mamịrị na mmebi nke retina site na mmepe nke ìsì. Maka nyocha nke ọrịa mamịrị retinopathy nke ọrịa mamịrị, ọ dị mkpa ka afọ ise gachara site na mpụta ọrịa shuga, nyocha nke ọma nke mgbanwe na fundus na vaskụla ọnya ọrịa nke anya nke ụlọ ọgwụ ophthalmologic ma na-esochi 1-2 ugboro otu afọ site na onye na-ahụ maka iku anya na ebumnuche nke mgbazi oge nke ọrịa mamịrị retinopathy site na iji photocoagulation.

Polyneuropathy
A na - amalite nsogbu a nke ọrịa shuga n'oge. Ingutọ iche:

Pnepheral polyneuropathy, nke na-egosipụta onwe ya na nkwarụ nke enweghị isi na mmetụta miri emi. Maka nchoputa ya, eji ihe omumu ihe elektrik eme ihe ugbua. N'ime ọgwụgwọ ha, a na-eji usoro α-lipoic acid (Espa-lipon, Thioctacid, Berlition) na vitamin B1 na B6 (Milgamma) mee abụba.

Kwurula, nke ha mata ọdịiche: obi ọrịa mamịrị, ọrịa mamịrị, mamịrị enteropathy, ọnya ụbụrụ na-arịa ọrịa mamịrị. Nchoputa ha dabere na data nyocha na akwara. A na-eji Cardiotrophs, prokinetics, physiotherapy na ọgwụgwọ.

Encephalopathy na-arịa ọrịa shuga
N'ihe banyere ọrịa labile n'ụzọ ịba ọcha n'anya, ọ ga-ekwe omume ịzụlite mgbanwe na ọnọdụ mmetụta uche na akparamagwa - encephalopathy.

Mgbakwunye nsogbu na usoro mmepe gụnyere:

Lipodystrophy na ntinye insulin.

Hepatosis nke imeju abụba na-akpata n'ihi ụgwọlata nke carbohydrate na abụba metabolism.

Ọrịa mamịrị na-arịa ọrịa shuga - ọrịa metabolic nke obere nkwonkwo aka.

Lipoid necrobiosis bụ ụdị vasculitis, panniculitis.

Ugbu a, anyị anaghị ezute ọrịa Moreak na Nobekur, nke ndị toro eto na mmepe mmekọrịta nwoke na nwanyị ji.

Polydipsia - gịnị ka ọ bụ?

Ọ bụ ezie na okwu ahụ bụ “polydipsia” nwere otu mkpụrụ Latin dị ka akpọpụta “ụmụ” (poto ՛ m - njikọ na mmiri, n'ihi ya American Potomac na hippo), ọdịiche dị n'etiti ha buru nnukwu ibu.

Ọrịa ụbụrụ na-apụta "ihe na-akpata nsogbu," ebe polydipsia (n'ụzọ nkịtị: ị plentyụ ọtụtụ) bụ ezigbo mmiri chọrọ.

Ihe omume polydipsia bụ isi bụ nsogbu nke ọrụ nke etiti akpịrị ịkpọ nkụ (ma ọ bụ ebe a na-a drinkingụ mmanya) na nsonaazụ ya n'ihi ọnụnọ nke ọrịa pituitary-hypothalamic ma ọ bụ n'ihi nsogbu nke uche - maka ọdịdị nke nke abụọ, a na-enwe ntụgharị nke ihe mejupụtara ọbara na-ekesa, nke na-akpali mmeghachi omume nke etiti a.

Na mgbakwunye na ihe kpatara ebumnuche nke uche - schizophrenia na ihe ndị ọzọ, enwere ụdị ụdị polydipsia nke mbụ (idiopathic), nkọwa nke sayensị enweghị ike inye.

Thedị adị nke echiche mmụọ: polygenesia nke psychogenic metụtara nkwenkwe enweghị mgbagha na mkpa ị drinkụ nnukwu mmiri (ma ọ bụ oftenụọ mmiri mgbe ọ bụla, na obere doses).

Ndi oria n’onwe ha gosiputara onodu ha site n’inwe “asacha” ahihia na “mmebi” site n’ahu, ma obu site na mmezu nke onyinye, nke butere “ndu ndu” nke gwọ oria nile ma mee ka ndu ha di ogologo.

Ihe ize ndụ nke polydipsia nke psychogenic etiology dị na ohere nke ịgbanye ọbara electrolytes (sodium) n'ọnọdụ nke na-eyi ndụ egwu, nke nwere njikwa ọdịdọ na ụbụrụ na-esote.

Vidiyo si na Dr. Malysheva:

Physiological na pathologies akpata

Ihe kpatara nmuta nke akpiri akpiri gha aru nwere ike buru ihe nwudoro obara obara ya na nnu n’ime mmiri ahu:

• site na ikpo oku
• ụdị arụmọrụ ọrụ dị egwu,
• njirimara mmadụ nke sistemụ ụjọ (sweating n'ihi ihere, obi amamikpe, iwe), na ihe ndị ọzọ.

Ihe mere maka ogwugwu ihe nnabata bu mmụba nke ihe mejupụtara ọbara n’ime ihe ndị na - egosi ndụ na - egbu mmụọ, n’agbanyeghi na enwere oke mmiri (mmiri) zuru oke n’ime ọbara n’oge.

Yabụ, oge ụfọdụ iji mee ka ịbawanye ụba nke glucose n'ọbara anaghị achọ mbelata olu nke mgbasa - ọ na-abawanye maka ihe ndị ọzọ.

Dịka ọmụmaatụ, polydipsia na ọrịa shuga mellitus, yana hyperglycemia nke ya na oge, na ịkọwapụta site na homonụ - insulin erughi, na-eduga ntopute ya na nkụchi na - enweghị atụ maka ọrịa ọzọ dị oke mkpa - polyuria (mmamịrị ngwa ngwa na nnukwu mpịakọta, na - ewetara onye ọrịa ahụ ike ọsụsọ zuru oke - nsụgharị nkịtị. okwu aria mamiri putara oria shuga.

Ihe ọzọ na - akpata akpịrị ịkpọ nkụ na - enweghị isi bụ ọnụnọ ọrịa ọzọ kpatara enweghị mgbakasị hormonal - na - arịa ọrịa shuga, ma na - arịa ọrịa shuga.

Mgbaàmà na ihe ndị metụtara ya

Ebe ọ bụ na mmiri mmiri na nsogbu a karịrị nkezi physiological ụkpụrụ maka ahụ na ọnọdụ ihu igwe na nkezi ike oriri (ihe karịrị 2 l / ụbọchị), hemodilution (mbufu ọbara na mmiri) eduga enweghị isi na ya electrolyte mejupụtara - n'ihi nke a, ọgba aghara na-egosi na ọrụ nke niile ahu sistemu:

Dysfunction system of muscular system in the nway (anoe na - ebido) na - esite na ndagwurugwu akwara, ndi n’achoghi anya; na udiri ihe (ya na obara nke uku), oria dika oria akwara.

N'iburu n'uche na “ụzọ akwara” gụnyere ọ bụghị naanị ọkpụkpụ, kamakwa olu dị larịị, enwere nbibi nke ọrụ:

• obi (na mmepe nke arrhythmias, ike na-ezughi ezu nke contractions obi),
• akụkụ ahụ dị omimi.

Udiri nke akwara ọbara na-agbanwe (ya na ogo ịba ụba na mbido ya na ọdịda ya na njedebe nke nsogbu ahụ) - ihe ngosi dijitalụ nke enwere ume na ọbara mgbali elu ibido, wee daa.

Otu ihe na-eme na afọ, eriri afọ, endocrine na exocrine glands - a na-ejikwa ụdọ ahụ akpụ akpụ.

Ngwakọta nke mmiri n’ime ahụ na-eduga na ọrịa ọrịa edema, nke a na-egosipụta na mbụ na mkpokọta mmiri n’ime ahụ (ọkachasị, ascites), na mgbe ahụ - ọdịdị nke edem na mpụta.

Nyere nnabata nke inye ọbara n’ ụbụrụ n’arụ n’arụ dị n’ọkpụkpụ ọbara, nsị ya na-eduga n’ọgba aghara n’arụ ọrụ na sistem niile, na oke ihe na-enye nsogbu.

N'ihi ịdị adị nke ndị a, na-emegide ngbanwe nke mgbanwe glucose ọbara dị n'ọbara, mgbanwe na-eme ngwa ngwa karịa, na-adịte aka ma na-achọ nnukwu mbọ karịa akụkụ ahụ na ndị ọrụ ahụike iji kwụọ ụgwọ.

Diagnostics

E gosipụtara ịdị adị nke ọrịa shuga - ma shuga ma ndị na-abụghị shuga (ma ọ bụ echiche nke ọnụnọ ha) site na akara ndị nwere ike ịmara onye ọrịa ahụ n'onwe ya, yana data nyocha.

Akụkụ nke mbụ gụnyere polydipsia n'azụ:

• polyuria
• polyphagy (agụụ na-adịghị eju afọ),
• akọwaghị ihe kpatara oke ibu,
• ihe ojoo ojoo (ike gwụ oke, ike ọgwụgwụ, nsogbu nke nghọta na ọrụ uche),
• Ihe mgbaàmà akpọnwụ akpịrị (site n’ọnụ akọrọ - ruo n’ọrịa akpịrịkpa: itching, peeling, ihe ngbu, ọnya, ọbara ọgbụgba),
• glucosuria (uto nke mmamiri uto).

A na-enyocha ihe mgbaàmà ndị a site na nnwale nke ụlọ ọgwụ:

• nnwale mmamịrị na ọbara shuga (gụnyere mkpebi nke ọnụọgụ haemoglobin glycated na usoro ndị ọzọ),
• ọdịdị nke profaịlụ glycemic,
• Mkpebi ọkwa nke homonụ dị n'ọbara,
• nyocha nke ọrụ nke anụ ahụ site n’aka ndị dibia ọkachamara (endocrinologist, neuropathologist, optometrist).

Site na insipidus ọrịa shuga (nephrogenic ma ọ bụ pituitary), nsogbu a ga-adị iche na ọrịa biochemical ndị ọzọ na usoro nke mmiri mmiri.

Usoro ọgwụgwọ

Ọgwụgwọ na-adabere n’ihe kpatara polydipsia.

Site na usoro ọmụmụ ya na-arịa ọrịa shuga, a na-emezi mgbazi:

• homonụ nke mmalite
• sistemu na aru ya
• usoro metabolic na anụ ahụ,
• nri nri nke onye ọrịa nwere mgbanwe na ụdị ndụ ya.

Imezu ebumnuche mbụ ga - ekwe omume site na ịdepụta ndị na - ebunye shuga ma ọ bụ insulin, ndị na - esochi mmezi ọgwụgwọ dabere na usoro ọbara na mmamịrị.

Therụ nke abụọ chọrọ iji ọtụtụ ndị na - ahụ maka ọgwụgwọ: nchikota nke diuretics (Lasix na ndị ọzọ) na - eji usoro ịgbagharị mmiri (iwebata usoro site na ụzọ mgbapụta mgbe ọ gaghị ekwe omume ị doseụ mmiri mmiri ị na-a )ụ).

Imeghari nguzogide nnu-mmiri bu mbido usoro nke iweghachi oru ndi ahu na aru ya, ma odi nkpa, eji ogwu eme ihe.

• antispasmodic (magnesium sulfate, Papaverine),
• analgesic tinyere antihistamine (Analgin tinyere diphenhydramine),
• ogwugwo na ogwu ogwu (Radedorm) ma ọ bụghị.

Ojiji nke Riboxin na ndị ọzọ na-eme ka metabolism anụ ahụ dịkwuo elu, na-akpata mmetụta antihypoxic, nwere ike melite ọnọdụ nke akụkụ ahụ na anụ ahụ, wee bulie ụda olu nke anụ ahụ dum. Ọ bụrụ na ọ dị mkpa, a na-enye ọgwụ ọgwụ maka otu nzube.

N'iburu n'uche egwu dị na onye ọrịa shuga ịhapụ ụlọ na enweghị ike ngwa ngwa iji mee ka ọnọdụ ya ka mma, ọ dị mkpa ịkụziri ya nkwenkwe ọhụrụ banyere ọrịa ya, nyocha nke ọma na usoro nyocha kwa ụbọchị yana mmụba na mmega ahụ na mmekọrịta mmadụ na ibe ya.

Nri mamịrị kwesiri ị attentionụ obere ume (yabụ na achọrọ ibibi ụfọdụ nkwenye siri ike maka uru ma ọ bụ ihe oriri ụfọdụ).

Site na nyocha nke oge, ịchọpụta ihe kpatara polydipsia na imezu ndụmọdụ nke dọkịta ọkachamara, ọ dị mma; ọ bụrụ na eleghara ha anya, enwere ike ịnwe coma na nsonaazụ na-enweghị atụ.

Ihe omume anụ ahụ

Nke mbu, aga m acho ilebara polydipsia anya ihe ndị metụtara gburugburu ebe obibi. Physicalba ahụike, mmụba dị elu ma ọ bụ na mpụga, ọnọdụ na-akpata nrụgide, nwere ike ịkpasu mgbaàmà a, mana ọ gaghị egosipụta ọrịa ọ bụla. Ọzọkwa, enwere ike ịhụ akpịrị ịkpọ nkụ na ụmụ nwanyị dị ime, nke dịkwa ezi.

Ihe ọzọ kpatara polydipsia physiological bụ nri. Nri dị ụtọ, nri dị ụtọ ma ọ bụ oseose nwere ike ibute akpịrị ịkpọ nkụ, yana mmanya.

Ajụjụ ọzọ bụ mgbe akpịrị akpọ nkụ na-enweghị mmetụta nke ihe ndị dị na mpụga. Yabụ, dịka ọmụmaatụ, ịba ụba chọrọ mmiri nwere ike ikwu maka:

• ahụ ọkụ
• ọbara ọgbụgba
• ọzịza
• hydrothorax (uto n'ime oghere obi),
• ascites (uto n’ime eriri afọ).

Ezigbo nkụda mmụọ n’ime mmadụ nwekwara ike ibute oria ma ọ bụ ọgbụgbọ.

Polydipsia Psychogenic

Varidị ọzọ bụ polygenpsia psychogenic metụtara nsogbu uche.

Ọzọkwa, ihe mgbaàmà nke akpịrị ịkpọ nkụ mgbe niile nwere ike igosi ọnụnọ nke ọtụtụ ọrịa, nke mbụ, ọ bụrụ na onye ọrịa ahụ na-eme mkpesa banyere mkpa ọ fluidụ mmiri na-achịkwaghị achịkwa, dọkịta ahụ ga-enyo enyo. ọrịa shuga. N'okwu a, nchọpụta dị iche dị mkpa, ebe ọ bụ na enwere ọrịa shuga na ọrịa insipidus. Thegwọ ọrịa ndị a, dị ka ihe na-akpata mmepe, dị iche, mana ihe ngosipụta ahụ nwere ike ịdị oke.