Tujeo Solostar - insulin ọhụrụ na-arụ ọrụ ogologo oge, nyocha

A na - eji insulin agwọ ndị ọrịa nwere ụdị ọrịa shuga mellitus nke 2, ụdị ọrịa na - akpata ọrịa shuga. Ojiji ha ji eme ihe bara uru nwere ike belata ogo glucose di elu ma gbuo oge mmepe nke nsogbu. Otutu na ebe ochichi nke ogwu si dabere na oge ihe o mere.

Nrụpụta na nchekwa nke Tujeo Solostar

N'etiti Tujeo Solostar na Lantus, ọdịiche ahụ doro anya. Ojiji nke Tujeo jikọtara ya na obere ịdị uchu nke ịmalite ọrịa hypoglycemia n’ebe ndị ọrịa nwere ọrịa shuga nọ. Ọgwụ ọhụrụ ahụ achọpụtala ihe kwụsiri ike ma dịtee aka ma e jiri ya tụnyere Lantus otu ụbọchị ma ọ bụ karịa. O nwere nkeji okpukpu atọ karịa nke ihe na-arụ ọrụ kwa 1 ml nke ngwọta, nke na-agbanwe akụrụngwa ya nke ukwuu.

Ntọhapụ nke insulin na-eji nwayọ, wee banye n'ọbara, ogologo oge na-eduga n'ịchịkwa ọnya glucose dị n'ọbara n'oge ụbọchị.

Iji nweta otu ụdị insulin ahụ, Tujeo chọrọ olu olu okpukpu atọ karịa nke Lantus. Ọkpụkpụ ahụ agaghị adị ụfụ n'ihi mmụba mpaghara ebe ọdịda. Na mgbakwunye, ọgwụ dị na obere olu na-enyere aka nyochaa nke ọma na ntinye ya na ọbara.

Ngosiputa puru iche na nzulite insulin mgbe ewerechara Tujeo Solostar bu ndi a na-acho insulin ndi mmadu n’enweghi nsogbu nke insulin choputara.

Kedu onye nwere ike iji insulin Tujeo insulin

A nabatara iji ọgwụ ahụ maka ndị ọrịa agadi karịa afọ 65, yana ndị ọrịa mamịrị nwere akụrụ gbasara akụrụ.

N’oge agadi, ọrụ akụrụ nwere ike ịka njọ nke ukwuu, nke na-eduga n’ibelata mkpa nke insulin dị. Na ọdịda akụrụngwa, mkpa insulin na-ebelata n'ihi mbelata metabolism metabolism. Site na nkwarụ imeju, mkpa na-agbadata n'ihi mbelata ikike gluconeogenesis na metabolulin metabolism.

A naghị atụ aro iji Tujeo Solostar n'oge ime na lactation, ọ ka mma ịgbanye nri dị mma.

Ntụziaka maka iji Tujeo Solostar

Insulin Tujeo dị dị ka ọgwụ mgbochi, nke a na-ahụ otu oge n'oge ọ bụla, mana ọkacha mma kwa ụbọchị. Ọdịiche kachasị na oge nchịkwa kwesịrị ịbụ 3 awa tupu ma ọ bụ mgbe ọ bụla.

A na-achọ ndị ọrịa na-atụfu oge ịlele ọbara ha maka itinye uche glucose, ma laghachi n'ụzọ nkịtị otu ugboro kwa ụbọchị. N'ọnọdụ ọ bụla, mgbe ịwụsịrị, ịnweghị ike ịbanye ugboro abụọ iji mejupụta maka echefuru echefu!

Maka ndị ọrịa nwere ụdị shuga 1, a ga-enye insulin Tujeo insulin na-eme ngwa ngwa n'oge nri iji kpochapụ mkpa ọ dị.

A ga-ejikọrị ndị nwere ụdị insulin Tujeo 2 na-arịa ọrịa shuga na ọgwụ hypoglycemic ndị ọzọ. Na mbu, a na-atụ aro iwebata 0.2 U / kg ruo ọtụtụ ụbọchị.

EGO. Tujeo Solostar na-achịkwa subcutaneously! Can nweghị ike ịbanye na ya intravenively! Ma ọ bụghị ya, enwere ihe ize ndụ nke hypoglycemia siri ike.

Nzọụkwụ 1 Wepu sirinji si na friji otu awa tupu ịhapụ ya, hapụ ya na ụlọ okpomọkụ. Nwere ike tinye ọgwụ oyi, mana ọ ga-egbu gị mgbu karịa. Gbalia nyochaa aha insulin na oge mmebi ya. Na-esote, ịkwesịrị iwepu okpu ma lerukwuo anya ma ọ bụrụ na insulin ahụ pụtara. Ejila ya ma ọ bụrụ agba agba. Jiri akwa owu ma ọ bụ akwa nwere mmanya na-egbu egbu.

Nzọụkwụ 2 Wepu mkpuchi na-agbanye na agịga ọhụụ, kpoo ya na mkpịsị syringe ruo mgbe ọ kwụsịrị, mana ejila ike. Wepu okpu dị mpụta na agịga, mana atụpụkwa. Wepu wepu isi nke ime ma tufuo ya ozugbo.

Nzọụkwụ 3. Enwere mpio teepu na teepu na-egosi ego ole aga-aba. N'ihi ihe omumu ohuru a, achoghi ntule ntu ogwu. A na-egosi ike na nkeji otu maka ọgwụ ahụ, ọ bụghị ụdị analogues ndị ọzọ.

Buru ụzọ mee nyocha nche. Mgbe ule ahụ gasịrị, jupụta ntụtụ ahụ ihe ruru 3 PIECES, ka ị na-atụgharị onye na-ahọrọ ya ruo mgbe ntinye dị n'etiti ọnụọgụ abụọ na nke 4. Ọ bụrụ na mmiri mmịpụta na-apụta, mgbe ahụ mkpụrụ akwụkwọ sirinji kwesịrị ekwesị maka ojiji. Ma ọ bụghị ya, ịkwesịrị ikwugharị ihe niile ruo mgbe nzọụkwụ 3. Ọ bụrụ na nsonaazụ agbanwebeghị, mgbe ahụ agịga ahụ na-ezighi ezi ma ọ ga-eji dochie ya.

Nzọụkwụ 4 Naanị mgbe ịghasịrị agịga ahụ, ị ​​nwere ike ịkpọ ọgwụ ahụ ma pịa bọtịnụ ngbanye ahụ. Ọ bụrụ na bọtịnụ ahụ arụghị ọrụ nke ọma, ejila ike zere imebi. Na mbu, atọrọ ogwu a ka osooso, ihe kwesiri ka aganwoghari ya rue mgbe ntinye n’adiri ya na nkpuru a choro. Ọ bụrụ n’otu ntabi anya ihe ahọpụtara atụgharịrị karịa ka ọ tụgharịrị, ị ga-eweghachi ya. Ọ bụrụ na ezughị ezu ED, ị nwere ike tinye ọgwụ maka inje 2, mana iji agịga ọhụrụ.

Ihe ngosi nke mpio egosi: a na egosiputa nọmba n’obere isi, a na-egosiputa onu ogugu n’oghere n’agbata n’agugu. Inwere ike ịkpọ mkpirisi 450 ka ọpinye ederede sirinji. A na-eji mkpịsị sirinji nke mkpụrụ ọgwụ nke 1 ruo 80 mejupụta nke ọma ma jikwaa ya na nkeji 1.

A na-agbanwe usoro ịsụ oge na oge ojiji dabere na mmeghachi omume nke ahụ onye ọrịa ọ bụla.

Nzọụkwụ 5 A ga-etinye insulin tinye ya na subcutaneous abụba nke apata ụkwụ, ubu ma ọ bụ afọ na-enweghị imetụ bọtịnụ dosing. Mgbe ahụ tinye mkpịsị aka gị na bọtịnụ ahụ, pịa ya ahụ niile (ọ bụghị n'akụkụ akụkụ) ma jide ya ruo mgbe “0” pụtara na windo ahụ. Jiri nwayọ gụta ise, wee hapụ. Ya mere, a ga-enweta ọgwụ zuru ezu. Wepu agịga ahụ n’akpụkpọ ahụ. E kwesiri iji uzo ozo di iche iche megharia uzo ozo ohuru.

Kwụpụ 6 Wepu agịga ahụ: were mkpịsị aka gị were ọnụ nke nnukwu mpụta, jide agịga ahụ ogologo ma tinye ya na okpu mpụta, na-agbanye ike, jiri aka gị jiri mkpịsị ahụ na-agbaji ahịrị. Tinyegharịa ruo mgbe ewepụrụ agịga ahụ. Tụfuo ya na nnukwu ite mmiri nke dọkịta gị gwara gị. Jiri okpu mechie sirinji mechie ma etinyeghachi ya na friji.

1. Tupu ịgba ntụtụ niile, ịkwesịrị ịgbanwe agịga ahụ ka ọ bụrụ nke na-enweghị atụ. Ọ bụrụ na ejiri agịga ahụ ugboro ugboro, ntachiri nwere ike ime, n'ihi nke usoro ya ga-esi zie ezighi ezi,
2. Ọbụlagodi mgbe ị na-agbanwe agịga, naanị otu onye ọrịa kwesịrị iji ya mee ihe ma ghara ibunye ya ndị ọzọ.
3. Ewepula ọgwụ ahu na syringe na katriiki iji zere ị overụbiga ókè.
4. Mee ule dị mma tupu ọnya gị niile,
5. Buru ma ọ bụrụ na mfu ma ọ bụ arụ ọrụ ya, yana nhichapụ mmanya na arịa iji mee ihe,
6. Ọ bụrụ na ị nwere nsogbu n’ọhụụ, ọ kacha mma ka ị jụọ ndị ọzọ maka ọgwụ ha kwesiri,
7. Egwakọtala insulin Tujeo na ọgwụ ndị ọzọ,
8. Jiri mkpịsị sirinji kwesịrị ịmalite mgbe ị gụchara ntuziaka.

Na-agbanwe site na ụdị insulin ọzọ na Tujeo Solostar

Mgbe ị na-atụgharị site na Glantine Lantus 100 IU / ml ka ọ bụrụ Tugeo Solostar 300 IU / ml, ekwesịrị ịhazigharị ọgwụ ahụ, n'ihi na nkwadebe ndị ahụ abụghị ihe ọkụkụ, ọ naghị agbanwe agbanwe. Enwere ike ịgbakọ otu na ngalaba, mana iji mezuo ọkwa glucose chọrọ n'ọbara, a chọrọ ọgwụ Tujo 10-18% karịa nke Glargin.

Mgbe ị na-agbanwe insulin basal na-adị ogologo ma na-arụ ọrụ ogologo oge, o yikarịrị ka ị ga-agbanwe dose ahụ ma dozie usoro ọgwụgwọ hypoglycemic, oge nchịkwa.

Ọ dị mkpa ka ị na-eme nyocha ahụ mgbe niile ma soro dọkịta gị gaa n'ime izu 2-4 ruo mgbe ị gbanwee insulin. Mgbe ọ gbalitechara, a ga-emezigha usoro usoro ọgwụgwọ ahụ. Na mgbakwunye, achọrọ mmezi mgbe ị na-agbanwe ibu, ụdị ndụ, oge nchịkwa nke insulin ma ọ bụ ọnọdụ ndị ọzọ iji gbochie mmepe nke hypo- or hyperglycemia.

General njirimara

Sanofi na - emepụta ọgwụ mgbochi dị elu. Insulin "Tujeo" bu mmepe ohuru, nke dabere na usoro glargine. Ngwakọta nke SoloStar nwere ụmụ irighiri glargine - ọgbọ ọhụrụ nke insulin. N'ihi nke a, ngwá ọrụ dị mma maka nnwale insulin nke ogo siri ike.

Ọgwụ a zuru ụwa ọnụ ma akwadoro maka iji ụdị 1 na ụdị shuga 2. Site na ọgwụgwọ insulin nke Toujeo, ọ dịghị mkpa ileba ahụ ọ bụla anya ma ọ bụ kwụsị ọgụ nke hypoglycemia.

Ngwaahịa a bụ mmiri doro anya, nke enweghị agba. Dị na katalọgụ iko nke 1.5 ml. A na-etinye ya n’ime mkpịsị odere Tujeo SoloStar mbụ. N’ime kaadiboodu pensụ 1, 3 ma ọ bụ 5.

Analogues nke SoloStara dịka usoro nke usoro na ihe mejupụtara bụ Tresiba, Peglizpro, Lantus, Levemir, Aylar.

A machibidoro ọgwụ a na ketoacidosis ọrịa shuga, ụmụaka na ndị na-eto eto na-erubeghị afọ 18, yana ndị mmadụ n'otu n'otu ghara ịnabata ya.

Ejiri nlezianya debe ndị ọrịa nwere ọrịa nke sistemụ endocrine, ndị agadi kariri afọ 60 nwere nsogbu gbasara akụrụ na ndị ọrịa nwere ọrụ imeju.

Omume ọgwụ

“SoloStar” nwere nnukwu usoro glycemic enweghị nnukwu ike, nke na-ejigide ọgwụgwọ ọgwụgwọ maka awa 24-35. Iwepu ọkara ndụ bụ awa 19. "Tujeo" - ọgwụ eji eme ihe ogologo. Jiri nwayọ nwayọ, kesaa nwayọọ nwayọọ.

Isi ihe bụ mkpali nke metabolism. Ọgwụ na - eme ka nnweta glucose site na nsụkọrọ akwara - ike na abụba. Tujeo SoloStar na-egbochi mmepụta glucose site na sel sel imeju. Ihe na-arụ ọrụ bụ glargine, analogue nke insulin na-eme ka mmadụ nwee ike na-egbochi lipolysis na adipocytes. N'otu oge ahụ, ọ na-agbadata ọnụego nke proteolysis ma bido imepụta protein, nke dị mkpa maka ịnwe glucose. Usoro metabolic a na - eme ngwa ngwa, n'ihi nke a na - achọpụta nsonaazụ ya ozugbo nchịkwa gasịrị.

N'ihi ihe dị ogologo oge nke ọgwụ ahụ, ọ bụrụ na ọ dị mkpa, ịnwere ike ịhazigharị oge ntụtụ ma bulie etiti oge n'etiti usoro. Mgbe ị na-ewere Tujeo Solostar, nchịkọta nke glucose n'ọbara na-eji nwayọ nwayọ. Nke a ga - enyere gị aka ịhọrọ ọgwụ dị mma maka ọgwụ insulin na - enweghị juputara na shuga ọbara na mberede.

Ọgwụ ahụ dịkwa irè n'agbanyeghị agbụrụ nwoke na afọ onye ọrịa. Enwere ike inye insulin n'otu oge ma ọ bụ na nhazi mgbanwe. Nchekwa maka ndị agadi, karịa 65, yana ndị ọrịa nwere nsogbu. Ọ na-akwado ọnọdụ physiological nkịtị nke onye ọrịa, na-egbochi mmepe nke nsogbu.

Ọdịiche dị na SoljoStar na Lantus

Sanofi weputara insidra Apidra, Insumans, na Lantus. SoloStar bụ anaantant dị elu nke Lantus.

Enwere ụfọdụ ọdịiche dị n'etiti SoloStar na Lantus. Nke mbu, obu ntinye. SoloStar nwere 300 IU nke glargine, Lantus nwekwara 100 IU. N'ihi nke a, ọ dị mma maka ogologo oge.

Site n’iwebelata ogo iku ume, Tujeo SoloStar jiri nwayọ wepụta homonụ. Nke a na-akọwa ohere belata ọrịa obi ịba ụba nke ehihie ma ọ bụ nsogbu ịrịa mamịrị na mberede.

A na - achọpụta nsonaazụ mgbe sc of 100 IU nke glargine gasịrị karịa mgbe ọ gbasịrị 300 300. Ọrụ ogologo oge nke Lantus anaghị adịru awa 24.

Tujeo SoloStar na-ebelata ohere nke ịmalite ịrịa ọrịa hypoglycemia siri ike site na 21-23. N'otu oge ahụ, ihe ngosipụta maka ibelata ọdịnaya nke hemoglobin glycated na SoloStar na Lantus fọrọ nke nta ka ọ bụrụ otu. “Glargin” na 100 na 300 dị mma maka ọgwụgwọ nke ndị ọrịa mamịrị.

Mwepụta wepụtara ya na ihe mejupụtara

Ogwu a di n ’uzo nke osisa nye ochichi subcutaneous (sc): ihe dika mmiri n’enweghi inyoghi ma obu nke n’enweghi oria nke nwere uzo puru iche (1.5 ml nke obula n’ime katriiki nke n’enweghi ocha) 5 katọn na ntuziaka maka iji Tujeo SoloStar).

Na 1 ml nke ihe ngwọta nwere:

• ihe na - arụ ọrụ: insulin glargine - 10.91 mg, nke kwekọrọ na 300 PIECES (otu ihe),
• ihe inyeaka: glycerol 85%, zinc chloride, hydrochloric acid, metacresol (m-cresol), sodium hydroxide, mmiri maka injection.

Mlọ ọgwụ

Usoro nke ihe dị n’ime ya bụ Tujeo SoloStar, insulin glargine, bụ n’ịhazi usoro glucose site na iwetulata ọbara ya n’ime ọbara site na igbochi nguzobe nke glucose na umeji na - akpali mkpali ya site n’ọkpụkpụ akwara, adipose na akwara ndị ọzọ. Insulin glargine, na-ebelata lipolysis na adipocytes na igbochi proteinoly, na-abawanye njikọ protein.

Enwetara site na njikọgharị ọgwụ nke DNA (deoxyribonucleic acid) nke ụdị Escherichia coli (nje K12) ejiri mee ihe dị ka nje na - emepụta ihe, insulin glargine nwere obere solubility na mpaghara na-anọpụ iche. Na pH 4 (acidic mats), insulin glargine na-agbaze kpamkpam. Mwepu nke mmeghachi nke acid nke ihe ngwọta mgbe etinyere ọgwụ ahụ n’ime abụba subcutaneous na-eduga na ịmepụta microprecipitate, nke na-ewepụta obere insulin glargine na-agbanwe agbanwe mgbe niile.

E jiri ya tụnyere insulin isophan, insulin glargine (100 IU / ml) ka ejiri nwayọ nwayọ nke mmetụta hypoglycemic pụta mgbe nchịkwa sc, a na-egosipụta ọrụ ya ogologo oge site na ichekwa otu.

Mgbe atụnyere insulin Tujeo SoloStar na insulin glargine 100 IU / ml, achọpụtara na mgbe sc nchịkwa nke ọgwụ ahụ na usoro ọgwụgwọ dị oke egwu, mmetụta hypoglycemic ya na-adịgide karịa ma dịgide ruo awa 24 ruo 36. Ime ihe ahụ agbagoro nyere ndị ọrịa, ọ bụrụ na ọ dị mkpa, ịgbanwe oge nchịkwa nke ọgwụ, na-arụ usoro ahụ n'ime awa 3 tupu oge ọ bụla.

Esemokwu dị n'etiti hypoglycemic action curves nke insulin glargine 100 IU / ml na Tujeo SoloStar nwere njikọ na mgbanwe na mwepụta nke insulin glargine insulin. Maka ntinye nke otu insulin glargine nke insulin glargine, onodu ogwu a choro okpukpu ato karia maka ochichi nke insulin glargine 100 IU / ml, nke a na - enyere aka belata mpaghara elu ugwu nke mkpali ya na iweputa ihe ya nke oma, ma o buru na insulin glargine 100 U / ml

Mmetụta hypoglycemic na nhazi intravenous (iv) nke usoro insulin glargine na insulin nke mmadụ hà nhata.

N'ihi biotransformation nke insulin glargine, etolite metabolites abụọ na-arụ ọrụ - M1 na M2. Dabere na nsonaazụ nke ọmụmụ vitro, ịdị ọcha nke insulin glargine na metabolites na-arụ ọrụ ya maka ndị na - anabata insulin na - emetụta insulin mmadụ.

Thedị nkọ insulin glargine dị maka uto insulin dị ka 1 (IGF-1) ihe dị ka okpukpu 5-8 dị elu karịa nke insulin mmadụ, mana ihe dịka 70-80 dị ala karịa nke IGF-1. M metabolites M1 na M2 dị ala karịa insulin mmadụ na mmekọrịta ha na nke onye na-anabata IGF-1.

N'ime ndị ọrịa nwere ụdị ọrịa shuga 1, mkpokọta ọgwụgwọ insulin glargine na metabolites ya dị ala karịa ọkwa achọrọ maka ọkara nke ejikọtara ya na ndị na-anabata IGF-1 yana mmụba na-esochi ụzọ mitogenic proliferative. Enwere ike ịgbalite ọkwa ọkwa physiological IGF-1, mana ọgwụgwọ insulin ọgwụgwọ n'oge a kpebiri n'oge Tujo SoloStar dị obere karịa mkpokọta ọgwụ dị mkpa maka nke a.

Nsonaazụ nke nnwale nke ọgwụ, nke metụtara ndị ọrịa nwere ụdị shuga mellitus 1 (ndị ọrịa 546) na ụdị ọrịa shuga 2 nke ndị ọrịa 2474, gosipụtara, ma e jiri ya tụnyere ụkpụrụ mbụ nke gemocololated hemoglobin (Hb)_A1c), mbelata nke ụkpụrụ ya site na njedebe nke ọmụmụ ahụ erughị nke ahụ mgbe ị na-eji insulin glargine 100 IU / ml.

Onu ogugu ndi oria ndi ruteworo n’agha_A1c (n'okpuru 7%), na usoro ọgwụgwọ abụọ bụ nke yiri.

Na njedebe nke ọmụmụ ahụ, ogo nke iwetulata ọkwa shuga dị ala na iji Tujeo SoloStar na insulin glargine 100 IU / ml bụ otu ihe. N'otu oge ahụ, rịba nwayọ nwayọ na mkpokọ glucose na plasma ọbara n'ọbara maka oge ịhọrọ dose n'oge ịgwọ ọgwụ.

N'icheta nsonaazụ ya na nchịkwa nke insulin glargine 300 IU / ml n'ụtụtụ ma ọ bụ mgbede, anyị chọpụtara na njikwa glycemic, gụnyere mmezi na Hb_A1cyiri. Mgbe enyere ọgwụ ahụ n'ime awa 3 tupu ma ọ bụ oge nchịkwa ọ na-ejikarị, ọ nweghị isi.

Na-emegide usoro ojiji nke Tujo SoloStar ruo ọnwa isii, enwere ike ịbawanye uru nke anụ ahụ na-erughị 1 n'arọ ga-ekwe omume.

Achoputara na oganihu na Hb_A1c okike, agbụrụ, afọ ma ọ bụ ịdị arọ nke onye ọrịa, oge ọrịa shuga mellitus (ihe na-erughị afọ 10, afọ 10 ma ọ bụ karịa) yana ụkpụrụ mbụ nke ihe ngosi a enweghị mmetụta.

Nsonaazụ nke nnwale nke ụlọ ọgwụ na ndị ọrịa nwere ụdị ọrịa shuga abụọ nke ọrịa mellitus egosiwo ọnọdụ dị ala nke ọrịa siri ike na / ma ọ bụ gosipụtara hypoglycemia, yana hypoglycemia nwere mgbaàmà nke ụlọ ọgwụ, karịa mgbe ejiri insulin glargine 100 IU / ml gwọọ ya.

N'ihe banyere iwelata ihe ize ndụ nke ịmalite ọrịa siri ike na / ma ọ bụ ekwenyeghị na hypoglycemia, uru nke Tujeo SoloStar karịa insulin glargine 100 IU / ml gosipụtara n'oge oge site na ọnwa nke atọ nke ọgwụgwọ ruo na njedebe nke ọmụmụ na 23% nke ndị ọrịa natara ndị na-arịa hypoglycemic ọnụ na na 21% nke ndị ọrịa were insulin na nri.

Ojiji Tujeo SoloStar na-ebute mbelata ihe egwu nke hypoglycemia na ndị ọrịa natara ọgwụgwọ insulin na mbụ, yana ndị ọrịa enwetabeghị insulin.

N'ime ndị ọrịa nwere ụdị ọrịa shuga mellitus nke 1, ọnọdụ nke hypoglycemia n'oge eji Tujeo SoloStar bụ nke a pụrụ iji tụnyere nke a na ọgwụgwọ insulin glargine 100 IU / ml. Ekwesịrị iburu n'uche na n'oge usoro ọgwụgwọ mbụ, ugboro ole mmepe nke ụdị hypoglycemia nke ala adịghị ala karịa ọgwụ kama ị insụ insulin glargine 100 IU / ml.

Nsonaazụ nke ọmụmụ egosipụtaghị ọnụnọ nke ọdịiche ndị metụtara njikọ nke ọgwụ mgbochi na insulin, yana na arụmọrụ, nchekwa, na usoro nke insulin basal mgbe atụnyere ndị ọrịa mesoro Tujeo SoloStar na ndị ọrịa mesoro insulin glargine 100 IU / ml.

Emere ihe omumu ihe omumu zuru ụwa ọnụ, nyocha nke ịba ụba insulin glargine 100 IU / ml na 12 537 ndị ọrịa nwere nnabata glucose, nwere nsogbu ibu ọnụ ma ọ bụ mbido ọrịa shuga nke afọ 2 ma gosipụta ọrịa obi. Otu ọkara ndị sonyere n'ọmụmụ ihe ahụ natara insulin glargine 100 IU / ml, nke a na-edenye aha ya ruo mgbe enwetara ọkwa glucose nke 5.3 mmol ma ọ bụ nke ala, ọkara nke ọzọ nwetara usoro ọkọlọtọ. Ọmụmụ ihe ahụ ruru ihe dịka 6.2 afọ.

Midia Hb_A1c, nsonaazụ ya bụ 6.4%, n'oge ọgwụgwọ dị na 5.9-6.4% na insulin glargine na 6.2-6.6% na otu usoro ọgwụgwọ.

Nsonaazụ atụnyere nke ọmụmụ a gosipụtara na, megide usoro ọgwụgwọ na insulin glargine 100 IU / ml, enwere ike nke nsogbu na-etolite ọrịa obi (enweghi ike igbu myocardial infarction ma ọ bụ ọnya na - abụghị ọnwụ, ọrịa obi), usoro ịtụgharị ma ọ bụ ụlọ ọgwụ maka mmepe nke nkụda obi, microvascular. nsogbu. Ihe mejuputara ihe omuma nsogbu nke microvascular gụnyere lasco photocoagulation ma ọ bụ vitrectomy, ọhụhụ nke anya n'ihi ọrịa mamịrị retinopathy, ngbanwe nke uche mgbakwunye creatinine, mmụba nke albuminuria, ma ọ bụ mkpa maka ọgwụgwọ ọrịa. Okike okike na agbụrụ anaghị emetụta arụmọrụ na nchekwa nke Tujeo SoloStar.

Na mkpokọta, enweghị ọdịiche na ịdị mma na nchekwa nke ọgwụ dị n'etiti ndị ọrịa nwere ụdị 1 na ụdị ọrịa shuga 2 nke afọ 65 na ndị okenye na ndị okenye. Iji zere mmeghachi omume hypoglycemic, na ndị ọrịa agadi, usoro mmalite na usoro mmezi kwesịrị ịdị ala karịa ka ọ dị na mbụ, a na-atụ aro ịba ụba nke iji nwayọ nwayọ nwayọ. N'ime ndị ọrịa agadi, ọ nwere ike isi ike ịchọpụta akara nke hypoglycemia, yabụ, ọ dị mkpa iji nlezianya nyochaa oke nke glucose na ọbara.

Enweghị data na nchekwa na arụmọrụ ojiji nke Tujeo SoloStar na ụmụaka.

Mlọ ọgwụ

Tụnyere insulin glargine, 100 PIECES / ml, mgbe nchịkwa s / c nke Tujeo SoloStar, a na-enweta ntinye insulin n'ihi nwayọ nwayọ na ogologo oge, na-eduga n'ịdị oge nlebara nwayọ karịa ruo awa 36. C_ss (ịgakọta ịta ọgwụ na plasma) n'ime ọgwụgwọ ọgwụgwọ na-enweta mgbe awa 72–66 jiri Tujo SoloStar were mee ihe.

Otu onye ọrịa ahụ nwere obere mgbanwe na sistem elele insulin maka awa 24 n'ogharị.

Insulin glargine bụ metabolized ngwa ngwa site n'akụkụ nkwụsị ụgbọxyl (C-terminus) nke agbụ beta, n'ihi biotransformation abụọ metabolites M1 (21 A -Gly-insulin) na M2 (21 A -Gly-des-30 B -Thr-insulin) na-etolite. . A na - ahụkarị metabolabolite M1 na plasma ọbara; sisitekwa sistem ya na-abawanye na nha nke ịrị elu nke insulin glargine. E guzobere na usoro ọgwụgwọ nke ọgwụ bụ tumadi n'ihi usoro ngosipụta nke metabolite M1, ebe ọ bụ na n'ọtụtụ ndị ọrịa insulin glargine na metabolite M2 adịghị ahụ ya na sistemụ sistemụ. N'ọnọdụ ndị ọzọ, ọkwa nke insulin glargine na metabolite M2 adabereghị na usoro nchịkwa insulin glargine nwere.

Ndi_½ (ọkara ndụ) nke metabolite M1, n'agbanyeghị ogo insulin glargine, dị na 18-18 awa.

Ntọala agbụrụ onye ọrịa ma ọ bụ okike nwere na pharmacokinetics nke Tujeo SoloStar edobeghị.

Enweghị ihe omuma banyere ogo afọ na ọgwụ ọgwụ nke ọgwụ. Iji zere ọnọdụ nke hypoglycemic na ndị ọrịa nwere ọrịa mellitus na ndị agadi, a na-atụ aro ka e nye usoro mbido na mmezi ya ka ọ dị ntakịrị ma na-abawanye ka ọ̀ ga-eji nwayọ nwayọ.

Emebeghị ka ụlọ ọgwụ ọgwụ Tujo SoloStar dị na ụmụaka.

Mgbe ị na - eme insulin nke mmadụ, achọpụtara mmụba nke insulin na ndị ọrịa nwere akụrụ na hepatic ezughi oke. A na-atụ anya mmetụta yiri nke ahụ mgbe ị na-eji insulin glargine, ya mere a na-atụ aro ka ndị ọrịa nwere ụdị a jiri nlezianya nyochaa ọkwa glucose ọbara ha.

Ihe ngbanwe

• dị obere karịa afọ 18 (ebe ọ bụ na nyocha ụlọ ọgwụ na-akwado ịdị irè na nchekwa nke ọgwụ na ụmụaka na ndị nọ n'afọ iri na ụma adịghị),
• hypersensitivity na mmiri ọgwụ.

Ekwesịrị ịkpachara anya banyere insulin Tujeo SoloStar n'oge afọ ime, ndị ọrịa agadi, na-arịa ọrịa endocrine na-enweghị afọ ojuju (gụnyere ezughi oke nke adrenal cortex na adenohypophysis, hypothyroidism), nnukwu ihe na-arịa arịa ma ọ bụ akwara akwara, retinopathy proliferative (karịsịa na enweghị photocoagulation) , oke ogo nke imeju, ọrịa na-eso ọnya afọ ma ọ bụ vomiting.

Tugeo SoloStar, ntuziaka maka ojiji: usoro na usoro onunu ogwu

Ezubere azịza ya maka iwebata abụba dị n'okpuru afọ nke afọ, ubu ma ọ bụ n'úkwù site na ntụtụ. A na-eme usoro ahụ otu oge kwa ụbọchị n'oge a kara aka. Maka ogwu ogbugba ọ bụla, ị ga-ahọrọ ọnọdụ ọhụrụ n'ime mpaghara akwadoro maka njikwa.

A na-egbochi nchịkwa mgbochi ọbara n'ime ọgwụgwọ ahụ!

Cannweghị ike iji insulin infusion pumping to the solution.

Ngwakọta mkpụrụ osisi sirinji nwere nkeji iri asatọ nke ihe a ga-eji mee nke a agaghị ewepụrụ na sirinji ọzọ ma ọ bụ nke ọtụtụ ndị ọrịa ji ya, ọ bụrụgodị na a dochiri agịga ahụ.

Ejiri mkpịsị ọria sirinji rụọ ya nke nwere nkeji 1. Ọ na-egosi ọnụ ọgụgụ nkeji nke insulin glargine a ga-elekọta.

Iji jikwaa ọgwụ a, jiri BD Micro-Fine Plus mkpa pụrụ iche maka pensụl sirinji SoloStar. Ọ bụ naanị maka iji otu oge. Thegba ọgwụ ugboro ugboro na-abawanye ohere ịlogụ ọgwụ na ị doụ ọgwụ ọjọọ, yana mmetọ na ibute ọrịa.

Mgbe ị na-eji mkpịsị akwụkwọ eme ihe na nke mbụ, a na-ewepụ ya na friji oge na-erughị elekere 1 tupu ịgba ọgwụ ahụ ka insulin wee nwee ụlọ ahụ ma na nchịkwa ya adịghị afụ ụfụ.

Tupu ntụtụ ọ bụla, ị ga-enyocha aha insulin na ụbọchị mmebi na mkpịsị edemede nke sirinji. A na-atụ aro igosi ụbọchị nke mmeghe.

Ebe mwepula isi ya na mkpịsị mkpụrụ sirinji, ọ dị mkpa iji anya nyochaa nyocha insulin. Ọ bụrụ na ihe ndị dị na katriiki ahụ nwere urukpuru, gbapụrụ ma ọ bụ tinye nke ala ọzọ, ngwaahịa ahụ kwesịrị ịhapụ. Ọnụnọ nke ikuku na insulin anaghị emerụ ahụ.

Mgbe ị jisiri ike na ngwọta ya dị ka mmiri dị ọcha, ị nwere ike ịga n'ihu usoro ahụ. Nke mbu, I kwesiri iwepu ihe ndi ahu n’azu n’azu n’apata na akwa etinyere n’ime ethyl mmanya. Were agịga ọhụrụ na, wepụpụ mkpuchi mkpuchi ahụ, na-enweghị mgbalị dị ukwuu, kpoo ya ruo mkpịsị sirinji. Jiri nwayọ wepu mpụta ya, ma tinye ya n'ime ajị ahụ.

Tupu ntụtụ ọ bụla, ọ dị mkpa iji duzie nyocha nchekwa, nsonaazụ nke kwesịrị ịnwepụta ọrụ ziri ezi nke mkpịsị sirinji, na-ewepụ ihe mgbochi nke agịga ma ọ bụ iwebata ọgwụ na-ezighi ezi nke insulin.

Iji duzie nnenne nchekwa, ịkwesiri idobe ntụhie na akara ngosipụta n'etiti ọnụọgụ abụọ na nke anọ, nke ga-adakọrịrị usoro atọ. Ọ bụrụ na dobe insulin na-apụta n'ọnụ ọnụ agịị ahụ mgbe ịpị bọtịnụ dose ahụ niile, ọ pụtara na mkpụrụ sirinji na-arụ ọrụ nke ọma. Ọ bụrụ na nke a anaghị eme, mgbe ahụ ị nwere ike ikwugharị ịpị bọtịnụ ntinye. Ọ bụrụ na-enweghị ntụpọ n'ọnụ ọnụ agịga mgbe agba nke atọ gasịrị, dochie agịga ma megharịa ule ahụ. Ọ bụrụ na dochie agịga ahụ arụpụtaghị nsonaazụ dị mma ma ule nchekwa ahụ kụrụ afọ ojuju, a ga-eji nke ọzọ dochie mkpụrụ ọgwụ sirinji. Ejila sirinji were nakọta mkpịsị ọdee.

Mgbe ule nchekwa ahụ gasịrị, akara ngosi a kwesịrị ịbụ “0”. Ka ịtọọ ọgwụ enyere, ị ga-edobe pointer na otu ahịrị na ogo achọrọ. Ọ bụrụ na ntụgharị na-atụgharị ihu na mberede karịa usoro achọrọ, ịkwesịrị ịgbanye ya.

Ọ bụrụ na ọdịnaya nke ọgwụ dị na katriiki erughị ọgwụ achọrọ maka nchịkwa, a ga-etinye ụzọ abụọ abụọ: otu si na sirinji dị ugbu a, nke ọzọ nwere ọnụọgụ insulin na-adịghị na ya. Ihe ozo bu inye ogwu nile eji achoro.

Onu ogugu (onu ogugu) nke di na window egosiputara gosiputara n ’uzo ihe ngosi putara, nomba dikwa iche iche na-egosi n’elu ahịrị n’agugu nomba.

Enwere sel insulin 450 na katriki, enwere ike ịtọ otu site na nkeji iri ato ruo iri asatọ na nkeji iri nke otu. Mkpụrụ akwụkwọ sirinji nke ọ bụla nwere ihe karịrị otu dose, ihe dị na katalọgụ na-enye gị ohere ikpebi ọnụ ọgụgụ nke insulin na-adịgide n'ime ya.

Maka ọgwụ ntụtụ, ịkwesịrị ịhọrọ ebe na, ijide mkpịsị mkpịsị ahụ site na ya, fanye agịga, mgbe ahụ, na-etinye mkpịsị aka gị na bọtịnụ dose, pịa ya niile wee jide ya n'ọnọdụ a. Nweghị ike ịpị bọtịnụ ahụ n'akụkụ, ịkwesịrị ijide n'aka na isi mkpịsị aka ahụ anaghị egbochi ntụgharị nke onye na-ahọrọ ọgwụ. Ọ dị mkpa ka ịdebe bọtịnụ ahụ ruo mgbe “0” pụtara na windo dose, ka ị na-agụta ruo ise. Naanị mgbe ahụ ka enwere ike ịhapụ bọtịnụ mwepụ ma wepu agịga ahụ.

Bụrụ na ihe isi ike na arụ ọrụ nke bọtịnụ dose ahụ, ekwesighi itinye ya n'ọrụ ka ọ ghara imebi pen sirinji. Ọ dị mkpa iji nyochaa ikike nke agịga ahụ site na nnwale nke nchekwa nke abụọ. Ọ bụrụ na bọtịnụ ahụ na-arụ ọrụ na-adịghị mma, dochie mkpịsị sirinji.

Mgbe ogwu ogbugba gasịrị, a ga-ewepụrịrị agịga site na iji mpụta nke agịga. Iji mee nke a, jiri mkpịsị aka abụọ ahụ wee were ngwụcha isi nke mpụta wee tinye agịga n'ime ya. Pụchie okpu ahụ ma, ijidesie akụkụ nile nke mpụta nke agịga ahụ, jiri aka ọzọ jiri mkpịsị pịpee.

A ga-atọrịrị agịga ahụ n'ime arịa ọkpọ na-egbochi.

Mgbe o wepụsịrị agịga, ekwesịrị iji okpu mechie sirinji ma dobe ya n'ebe echebere ọkụ na ikpo ọkụ. Etinyekwala sirinji ejirila na friji.

Ọ bụrụ na enwere obi abụọ ọ bụla gbasara arụmọrụ sirinji ọ kwesịrị ịrụ ọrụ ma ọ bụ ọ bụrụ na emebi emebila ya, ekwesighi iji ya; should kwesịrị ịgbalị ịrụzi ya. A na-atụ aro ka ejiri nwayọ nwayọ na - edozi ahụ: zere ịdaba na steeti siri ike, chebe site na kọntaktị na mmiri mmiri, uzuzu ma ọ bụ unyi, emela mmanụ. You nwere ike iji akwa mmiri ga-ehicha ihe n'èzí.

A na-atụ aro ka ị nwee mkpịsị sirinji ma ọ bụ obere akpa.

Dọkịta na-ekpebi usoro na oge nchịkwa nke Tujo SoloStar, na-eburu n'uche ebumnuche ebumnuche nke ịba ụba glucose n'ọbara n'otu n'otu.

A na-eme mmegharị insulin nke insulin na nlekọta dị ukwuu ma ọ bụ naanị dọkịta nke na-eburu n'uche ihe ndị na-akpata nchịkwa glycemic ezughị ezu, gụnyere mgbanwe na ahụ, ndụ onye ọrịa, oge nchịkwa insulin.

Tujeo SoloStar abụghị ọgwụ ịhọrọ maka ọrịa ketoacidosis na-arịa ọrịa shuga, maka ọgwụgwọ nke ọ ka mma iji nchịkwa ivul insulin na-adị mkpụmkpụ.

A na-adụ ndị ọrịa nwere ọrịa shuga ume ka ha na-enyocha oke ike glucose na ọbara.

Mgbe ị na-edepụta ọgwụ ahụ, onye ọrụ ahụike ga-agwa onye ọrịa ahụ nkọwa gbasara usoro nzọụkwụ nke usoro dị mkpa maka sc nchịkwa nke ọgwụ ahụ, wee nyochaa usoro nchịkwa onwe onye nke onye ọrịa iji jide n'aka na a na-eduzi insulin ahụ n'ụzọ ziri ezi.

N'ime ọgwụgwọ ụdị shuga 1, Tujeo SoloStar ka edepụtara ya na insulin, nke a na-ahazi n'oge nri ma na-achọ ndozi otu.

Maka ndị ọrịa nwere ụdị ọrịa shuga abụọ nke ọrịa mellitus, a na-atụ aro izizi mbụ nke Tujeo SoloStar ka ọ dị ka 0.2 PIECES kwa kilogram 1 nke ịdị arọ nke onye ọrịa na-esochi ya.

Mgbe ị na-agbanwe site na ọgwụgwọ insulin glargine 100 IU / ml gaa Tujeo SoloStar, ma ọ bụ nke ọzọ, ekwesịrị iburu n'uche na ọgwụ adịghị bioequurate na anaghị agbanwe agbanwe ozugbo.

Mgbe ọgwụgwọ insulin glargine gara aga, 100 IU / ml, enwere ike ịme ntụgharị gaa na Tujeo SoloStar na ọnụego otu n'otu. Agbanyeghị, iji mezuo mgbanye glucose plasma mgbaru ọsọ, enwere ike ịchọrọ insulin glargine 300 U / ml karịa.

Mgbe ị gbanwere site na Tujo SoloStar na insulin glargine 100 IU / ml, a ga-belata ntụtụ nke insulin ihe dị ka 20%, ma ọ bụrụ na ọ dị mkpa, a ga-aga n'ihu na-agbazi dose.

Mgbe ịgbanwere site na otu n'ime ọgwụ ndị a gaa na nke ọzọ, a na-atụ aro nlezianya metabolic n'ime izu mbụ 2-3.

Mgbe ị na-agbanwe site na insulin nke etiti ma ọ bụ ogologo oge na usoro ọgwụgwọ na Tujeo SoloStar, ọ nwere ike ịdị mkpa ịgbanwe ọgwụ nke insal basal ma dozie usoro na oge nke insulins oge dị mkpirikpi, analogues insulin na-arụ ọrụ ngwa ngwa ma ọ bụ ndị na-abụghị insulin hypoglycemic.

Mgbe ị na-agbagharị na insulin insal basal 1 otu oge kwa ụbọchị, enwere ike ịtọ dose nke Tujeo SoloStar dabere na ngalaba na ngalaba nke insulin na-achịkwa na mbụ.

Mgbe ị na-agbanwe site na iwebata insulin ugboro abụọ n’ụbọchị, mkpụrụ ọgwụ mbụ ga-abụ 80% nke ngụkọta kwa ụbọchị nke insulin aga.

Ọnụnọ nke ọgwụ mgbochi ọrịa na insulin mmadụ na ndị ọrịa na-enweta ọgwụgwọ na insulin insulin dị elu, na-eme ka nzaghachi insulin glargine 300 IU / ml dị mma.

Mgbanwe na usoro ọgwụgwọ ga-esonye ma jiri nlezianya anya nyocha metabolic.

Mmụba na mmetụta insulin megide ndabere nke njikwa metabolic dị mma nwere ike ịchọ nrụzi ọzọ nke usoro usoro onunu ogwu.

Otu nlekọta nke Tujeo SoloStar n'ehihie na-enye onye ọrịa ohere ịnwe usoro ịgba ntụtụ na, ọ bụrụ na ọ dị mkpa, gbanye awa 3 tupu oge ọrụ ahụ ma ọ bụ awa 3 gasịrị.

Etinyekwala insulin glargine 300 PIECES / ml ma obu tinye ya na insulin ndi ozo.

N'ime ọgwụgwọ ndị ọrịa agadi, ọ dị mkpa ilezi anya itinye uche nke glucose n'ọbara. Mgbe ị na-ahọrọ otu maka ụdị ndị ọrịa a, ọ dị mkpa iburu n'uche nsogbu na-aga n'ihu na ọrụ mkpo ha, nke nwere ike ibute mkpa mbelata insulin.

Maka ọgwụgwọ ndị ọrịa nwere ezughi oke akwara ma ọ bụ nke ọrịa ịba ọcha n'anya, enweghị ndụmọdụ ọpụrụiche na mgbazi usoro usoro onunu ogwu. Ekwesịrị iburu n’uche na ibelata metabolism nke insulin n’ime ụdị ndị ọrịa a nwere ike belata mkpa insulin, ya mere, ha chọrọ nlezianya nyocha nke ịba ụba nke glucose n’ọbara.

Ozi obere

Ọgwụ - insulin "Toujeo Solostar" nwere glargine ihe na-arụ ọrụ, nke nwere mmetụta na-adịgide adịgide, nke a na-achọ imebi oke mkpụrụ ndụ shuga dị n'ọbara. Ọ bụ ụlọ ọrụ ọgwụ a ma ama nke Sanofi mepụtara, bụ nke ama ama na mmepụta insulin nke ụdị ndị dị ka Insumans, Apidra.

Uru na Cons

Ogwu ahu agabigawo onwa ulo ogwu, obu ihe zuru oke nye aru mmadu. Mana dịka ọtụtụ ọgwụ, ọ nwere njirimara dị mma na nke na-adịghị mma. Egosiputara insulin Tujeo SoloStar n’egosiputa na udiri ogwu ndia:

• ọgwụ dị ogologo, nke na-adịgide ruo awa 32-35 na-enweghị ịbanye profaịlụ glycemic kachasị elu,
• adabara ọgwụgwọ ndị ọrịa nwere ụdị 1 na ụdị ọrịa shuga 2,
• ịta nke nọ n'ọrụ akụrụngwa dị nnọọ elu karịa nke analogues wee ruo ọkwa nke 300 nkeji kwa 1 ml,
• ruo oge 1, a na-ahụ maka obere ọgwụ nke ọgwụ ọgwụ dị na ọgwụ ntụtụ.
• na-ebelata ihe ize ndụ nke hypoglycemia n'abalị.
• Ihe ọghọm ndị dị na ọgwụ ahụ bụ ọnụnọ nke ihe ndị a metụtara otu ihe eji eme insulin nke ụdị a:
• contraindicated na ọnụnọ nke ọrịa mamịrị ketoacidosis,
• adabaghị maka ọgwụgwọ ndị ọrịa mamịrị nwere ọrịa ọnya akụrụ na imeju.
• mmeghachi omume nfụkasị na-arụ ọrụ nke ọgwụ ahụ nwere ike ịdapụta - glargine (nke egosipụtara n'ụdị rashes na-acha uhie uhie n'elu akpụkpọ ahụ nke cheeks, olu, ala akụkụ ya, afọ ya, na mpaghara ịgba ahụ, itching, ọrịra nke mucous membranes),
• Enweghị data nyocha na nchekwa nke ọgwụ n'ihe banyere ọgwụgwọ ụmụaka, yana ndị inyom dị ime.

Ihe ndị ọzọ insulin Tujeo SoloStar enweghị ọgwụ contraindications na erughị eru dị ịrịba ama na-egbochi ojiji ya dị ka ngwá ọrụ bụ isi na ọgwụgwọ nke ụdị 1 na ụdị ọrịa shuga 2. Emere ka amata iji ya maka ndị ọrịa nwere ọrịa shuga bụ ndị na-ebute oke ọrịa hypoglycemic.

Ihe dị iche na insulin Lantus

Tujeo nwere otu ihe di iche n’ihe banyere insulin Lantus. Ọ mejupụtara n'eziokwu ahụ bụ na SoloStar na-etinyekwu uche. Ihe nọ n'ọrụ n'ime ọgwụ ndị a yiri - ọ bụ glargine.

Ọgwụ ndị ọzọ enweghị ọdịiche pụtara ìhè. Nke otu ụlọ ọrụ ọgwụ German - Sanofi Aventis mepụtara.

Na uche nke dibia bekee, enwere ike dochie endocrinologist Tujeo na ọgwụ nwere njiri mara ya na ụdị ọrụ ahụ. Ndị a bụ ihe mkpuchi nke ihe ndị a:

1. Levemir nwere ihe dị n'ọrụ detemir na ihe mejupụtara ya. Ọ nwekwara mmetụta na-adịte aka, mana ọ bụghị ndọpụ.
2. Tresiba. A na-enweta mmetụta ọgwụgwọ ahụ n'ihi mmiri dehydlude, nke na-eme ka nchịkọta glucose dị n'ọbara n'ime obere oge.
3. Lantus. Ihe analog nke kacha dị nso na ọgwụ mbụ Tujo SoloStar.

Enwere ike iji ụdị insulin nwere ụdị ọgwụ ọgwụ ndị ọzọ dị ka ndị nnọchianya na usoro ọgwụgwọ nke ọrịa shuga mellitus iji zere mmalite nke hypoglycemia.

Ime na lactation

Ndị ọrịa nwere ọrịa shuga kwesịrị ịgwa dọkịta ha banyere afọ ime dị adị ma ọ bụ nke e mere atụmatụ.

Onweghi nnwale ulo ogwu na-eme nyocha site na iji ogwu Tujo SoloStar® nke nwanyi di ime.

Onu ogugu ndi nlebara anya (ihe kariri ihe omumu nke 1000 site n’ileghachi azu na ime ihe nlere anya) ya na ojiji insulin glargine 100 IU / ml gosiputara na o nweghi uzo o bula di n’iru na onodu imu ya, onodu imu nwa n’azu aru ma obu aru ike nke umu aka.

Na mgbakwunye, iji chọpụta nchekwa nke insulin glargine na insulin isofan na ụmụ nwanyị dị ime nwere ọrịa mellitus gara aga ma ọ bụ mmegharị ahụ, a na-eme nyocha nke meta nke nyocha ụlọ nyocha, gụnyere ụmụ nwanyị jiri insulin glargine 100 IU / ml n'oge afọ ime (n. = 331) na insulin ịnọpụ iche (n = 371).

Nyocha a meta egosipụtaghị ọdịiche pụtara ìhè gbasara nchekwa maka ahụike nne ma ọ bụ nwa amụrụ ọhụrụ mgbe ị na-eji insulin glargine na insulin isofan n’oge ime.

N'ime ọmụmụ anụmanụ, enweghị data dị omimi ma ọ bụ nke na-apụtaghị na ẹmbrayo ma ọ bụ mmetụta fetotoxic nke insulin glargine 100 IU / ml mgbe ejiri ya na onwa 6-40 ugboro karịa usoro a tụrụ aro na mmadụ.

Maka ndị ọrịa nwere ọrịa mellitus na-arịa ọrịa shuga ugbu a, ọ dị mkpa iji nwee usoro zuru oke nke usoro metabolic n'oge afọ ime iji gbochie ọdịdị nke nsonaazụ na-adịghị mma metụtara hyperglycemia.

Ọ bụrụ na ọ dị mkpa, enwere ike ịtụle iji ọgwụ Tujo SoloStar® n'oge afọ ime.

Mkpa insulin nwere ike ibelata n’oge ọnwa mbụ nke afọ ime, n’ozuzu ya, mụbaa n’oge ọnwa nke abụọ na nke atọ. Ozugbo amụrụ nwa, mkpa insulin na-agbada ngwa ngwa (ihe ize ndụ nke hypoglycemia mụbara). N'okpuru ọnọdụ ndị a, ịdị mkpa iji nlezianya nyochaa oke nke glucose n'ọbara.

Ndị ọrịa n’oge ị na-a breastụ ara nwere ike ịhazigharị usoro usoro insulin na nri.

Methodszọ ntụtụ

Ngwọta insulin dị na vials, katridges, dị ka akụkụ nke mkpịsị sirinji emechara. Ejiri ngwaọrụ pụrụ iche nye ọgwụ a. Ofzọ usoro mmeghe na iwu maka ijikwa ha dị iche.

Iji sirinji insulin a na-atụfu, ị nwere ike igba insulin ọ bụla, belụsọ Tujeo. Ejikwa ha iji duzie homonụ nke uto. Ọ dị mkpa iji hụ na itinye akara na sirinji "100 U / ml" kwekọrọ na ịta ọgwụ ahụ. N'ihi ntakịrị agịga dị ogologo (12 mm), a na-agbanye ya n'ime anụ ahụ n'okpuru ogo 45.

A pụrụ ịtụfu ihe eji ede sirinji (emee ya) ma tụgharịa ya:

• Firstdị nke izizi bụ ngwaọrụ nwere katọn arụnyere n’elu nwere ngwakọta insulin. Enweghi ike dochie ya, ma dee mkpịsị ederede eji.
• Na ngwaọrụ ndị eji emegharịgharị, enwere ike itinye kadi kadi ọhụrụ ma emechaa ya. Iji ntụtụ, a na-eji agịga ndị a na-atụfu agbasa Ọ bụrụ na ogologo ha agaghị agafe 5 mm, ọ dịghị mkpa ịrakọta anụ ahụ na ebe ntụtụ. Ọ bụrụ na agịga dị 6–8 mm, a na-agunye insulin n’otu ogo 90.

Mkpịsị sirinji bụ onye. Tupu i jiri ya, lelee ụbọchị ọ gwụrụ na aha ọgwụ ọ nwere.

Ọnụnọ nke ikuku na-egosipụta n'ụgbọ ahụ. A na-eme nyocha nchekwa tupu ntụtụ ọ bụla.

Iji mee nke a, a na-akpọ nkeji 3 nke insulin, emesia a na-agbanye bọtịnụ nchịkwa otu niile. Ọdịda nke dobe ngwọta na n'ọnụ agịga na-egosi ahụike nke aka.

Ma ọ bụghị ya, enwere ike ịmegharị ule ahụ ugboro atọ. Ọ bụrụ na nsonaazụ ya na-adịghị mma, dochie agịga ma ọ bụ pen sirinji n'onwe ya.

Maka ntinye nke nkpuru a choro meputa usoro ya site na iji ihe eji eme ihe. Onu ogugu ya na onu ogugu kwesiri igosi n’igbe “ihe”. Mgbe nke ahụ gasịrị, ha na-eji mkpịsị mkpụrụ ogwu agbaji, pịa bọtịnụ mmalite wee jiri nwayọọ gụọ ise. Nke a ga - enyere gị aka ịgba mbọ hụ na ngwọta niile rutere na saịtị ịgba agba.

Igwe mmiri insulin bụ ngwaọrụ a na-ebugharị ebugharị nke na-eme insulin n'ime obere usoro kwa ụbọchị. Ojiji na-enye gị ohere ịnọgide na-enwe shuga dị larịị.

• Ngwaọrụ gosipụtara ya, bọtịnụ akara ya na katrij,
• infusion set: a tube nke esite na ya dozie, na cannula, nke edoziri n’ime afọ,
• ihe mmetụta maka ịchọpụta glucose ọbara (n'ụfọdụ ụdị).

A na-eji nkwadebe Ultrashort maka mgbapụta ahụ. Usoro ọgwụgwọ insulin na ugboro ole insulin kpebiri site na dọkịta. A zokwara onye ọrịa ahụ ka ọ jiri ngwaọrụ ahụ. Enyere omume nke ọgwụ ndi ozo.

Ọdịmma nke ngwaọrụ bụ oke ụgwọ, mkpa iji dochie infusion setịpụrụ ụbọchị 3 ọ bụla.

Mgbe ịgaghị eji ya

Toujeo dị n'ụdị nke mmezi doro anya, akpọchiri na katriiki iko 1.5 ml. A na-etinye katriiki n’onwe ya n’ime mkpụrụ akwụkwọ sirinji maka otu oge. N'ime ụlọ ahịa ọgwụ, a na-ere ọgwụ Tujeo na igbe kaadi, nke nwere ike ịnweta pensụ 1.3 ma ọ bụ 5.

Toujeo ezubere naanị maka itinye ya n'ime anụ dị n'okpuru afọ, apata ụkwụ na ogwe aka. Ọ dị mkpa ịgbanwe saịtị ịgba ntụtụ kwa ụbọchị iji gbochie ịmalite nke scars na mmepe nke hyper- ma ọ bụ hypotrophy nke anụ ahụ dị n'okpuru ala.

Ekwesịrị izere iwebata insulin basal Tuino na akwara, n'ihi na nke a nwere ike ibute nnukwu hypoglycemia. Ogologo oge ọgwụ a na-adịgide naanị na ọgwụ ntụtụ. Na mgbakwunye, ọgwụ Tujeo enweghị ike iji ọgwụ insulin gbanye n'ahụ mmadụ.

N'iji pen-syringe mee ihe, onye ọrịa ahụ ga-enwe ike ibunye onwe ya site na iji nkeji 1 ruo 80. Na mgbakwunye, n'oge eji ya, onye ọrịa ahụ nwere ohere ịbawanye ọgwụ insulin site na otu 1 n'otu oge.

A na-agbakọta ọ̀tụ̀tụ̀ insulin na nkeji (nkeji). Enwere ike idozi ego ha ma ọ bụ dịgasị iche dabere na ọkwa nke glucose na ogo nke carbohydrates riri nri. A ga-azụrịrị ndị ọrịa niile na - enweta insulin n'ụlọ akwụkwọ ọrịa shuga.

Pụtara na mmetụta nke oge mmetụta, ogologo na ultra-ogologo-enye gị ohere iji nọgide na-enwe shuga shuga ụbọchị dum (basal akụrụngwa). A na-eji ha otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị.

Mkpirisi mkpirisi na ultrashort na-ebelata glucose, nke na-ebili mgbe e risịrị nri (mpaghara bolus). Edere ha tupu ma obu n'oge nri.

Ọ bụrụ na shuga buru ibu, a na-atụ aro ka ọ dịkwuo n’etiti nchịkwa ọgwụ na nri. Ngwakọta dị njikere nwere akụkụ abụọ ahụ.

A na-eji ha eme ihe tupu ha eriwe nri, ọ na-abụkarị ugboro abụọ n'ụbọchị.

N'ime ndị ọrịa nwere ụdị ọrịa shuga mellitus 1 na n'oge afọ ime, a na-eji insulin ọgwụ ike, nke gụnyere 1 ma ọ bụ 2 injections nke onye ọrụ basal yana iji mpempe obere na ultrashort tupu nri. Ekwuputara nchịkwa ọgwụ a maka ogo glucose dị elu.

N'ime ụdị shuga 2, enwere ike iji insulin basal jikọta ya na ọgwụ mbadamba mbadamba - 2-3 nke agba nke ngwakọta agwakọtara, usoro dị ike, ma ọ bụ ntụtụ bolus tupu nri. A na - ahọrọ ụdị ọgwụgwọ site na endocrinologist.

Toujeo Solostar bụ contraindicated maka ndị nwere ọrịa shuga na-erubeghị afọ 18 n'ihi enweghị nnwale ụlọ ọgwụ na ọgbọ a maka nchekwa nke ọgwụ ma ọ bụ maka nnabata nke Toujeo ma ọ bụ insulin glargine.

A na-adụ ọdụ ịkpachara anya maka ọgwụ:

• Womenmụ nwanyị dị ime (na njikọta na ọ ga-ekwe omume dochie anya ọgwụ a na-a afterụ mgbe ha mụsịrị nwa na oge ịtụrụ ime).
• Ndị okenye (ihe karịrị afọ iri asaa).
• Na-arịa ọrịa shuga na ọnụnọ nke ọrịa endocrinological.

Mgbe ị na-atụgharị site na otu insulin gaa na nke ọzọ, ọ dị mkpa ịmalite nyocha nke ndị endocrinologists, naanị a ga-ahọrọ. N'ọnọdụ ọnya ọnya na ọgbụgbọ na ọgbụgbọ, oke akụrụ ma ọ bụ ọdịda akwara, ọ dịkwa mkpa ịkpachara anya.

Ngalaba nke Tujeo SoloStar® (insulin glargin 300 IU / ml) na-ezo aka naanị Tujeo SoloStar®, ha ahaghịkwa na nkeji ndị ọzọ na-egosipụta ike nke ọrụ nke analogues insulin ndị ọzọ. Ekwesịrị ịnye ọgwụ Tujo SoloStar® s / c 1 oge kwa ụbọchị n'oge ọ bụla n'ụbọchị, ọkacha mma n'otu oge ahụ.

Ọgwụ Tujeo SoloStar® nke nwere otu ntụtụ n'oge ụbọchị na-enye gị ohere ịnwe usoro mgbanwe maka irigbu: ọ bụrụ na ọ dị mkpa, ndị ọrịa nwere ike ịgbanye 3 awa tupu ma ọ bụ awa 3 mgbe oge ha gasịrị.

Ekwesịrị ikpebi ma gbadoro mgbanye mgbanye glucose ọbara, oge na oge nchịkwa / nchịkwa nke ọgwụ hypoglycemic n'otu n'otu.

Enwere ike ịchọ nhazi mmezi, dịka ọmụmaatụ, mgbe ị na-agbanwe oke ahụ onye ọrịa, ibi ndụ, na-agbanwe oge nchịkwa insulin, ma ọ bụ n'ọnọdụ ndị ọzọ nwere ike ịbawanye atụmanya na mmepe hypo-ma ọ bụ hyperglycemia (lee.

"Ntụziaka pụrụ iche"). Mgbanwe ọ bụla na dose insulin kwesịrị iji nlezianya rụọ ya naanị ma ọ bụrụ na nlekọta nlekọta ahụike.

Tujeo SoloStar® abụghị insulin nke ịhọrọ maka ọgwụgwọ nke ketoacidosis na-arịa ọrịa shuga. N'ọnọdụ a, ekwesịrị inye mmasị na mbido insulin na-eme obere ọrụ.

N'ime ndị ọrịa niile nwere ọrịa shuga, a na-atụ aro ka nyochaa nke glucose n'ọbara.

Mmalite ị useụ ọgwụ Tujo SoloStar®

Ekwesịrị iji ndị ọrịa nwere ụdị ọrịa shuga mellitus nke 1. Tujeo SoloStar® otu ugboro kwa ụbọchị yana mgbakwunye insulin na-elekọta n'oge nri ma na-achọ nhazi onwe onye.

Ndị ọrịa nwere ụdị ọrịa shuga mellitus nke 2. Nlekọta mbụ akwadoro bụ 0.2 U / kg otu ugboro n'ụbọchị, na-esote nhazi nke otu.

Ọkpụkpụ sitere na nchịkwa insulin glargine 100 IU / ml na ọgwụ Tujeo SoloStar® ma, na ntughari, site na ọgwụ Tujeo SoloStar® ruo insulin glargin 100 IU / ml

Insulin glargine 100 IU / ml na Tujeo SoloStar® bụ ndị na - anaghị agbanwe agbanwe na - agbanwe agbanwe.

- Mgbanwe site na insulin glargine 100 IU / ml gaa Tujeo SoloStar® nwere ike ịme otu mpaghara, mana iji mezuo ebumnuche nke glucose plasma, enwere ike ịchọ ọgwụ Tujeo SoloStar® dị elu.

- Mgbe ị na-agbanwe site na iji Tujeo SoloStar® na insulin glargine 100 IU / ml iji belata ihe ize ndụ nke hypoglycemia, a ga-ebelata dose ahụ (ihe dị ka 20%), na-esote mmezi dose ma ọ bụrụ na ọ dị mkpa.

A na-atụ aro iji nlezianya nyocha metabolic n'oge izu ole na ole mbụ mgbe ọ gbanwechara otu ọgwụ ndị a gaa na nke ọzọ.

Na-agbanwe site na insulin basal ndị ọzọ na Tujeo SoloStar®

- Mgbanwe site na otu ntụtụ nke insulin insal n'oge ụbọchị gaa na otu nchịkwa nke Tujeo SoloStar® n'oge ụbọchị nwere ike rụọ site na ndabere nke otu akụkụ nke usoro insulin mbụ na-agbado na mbụ.

- Mgbe ị na-agbanwe site na nchịkwa nke insal insulin ugboro abụọ n'ụbọchị ka otu nlekọta nke nkwadebe Tujeo SoloStar®, usoro ntinye Tujeo SoloStar® na-atụ aro bụ 80% nke ngụkọta kwa ụbọchị nke insulin basal, ọgwụgwọ nke kwụsịrị.

Ndị ọrịa nwere insulin dị elu, n'ihi ọnụnọ ọgwụ mgbochi insulin na mmadụ, nwere ike ị nweta nzaghachi ka mma maka Tujo SoloStar®.

N'oge mgbanwe nke ọgwụ Tujo SoloStar® ma n'ime izu ole na ole mgbe ọ gasịrị, a na-atụ aro nlezianya metabolic anya.

Ofzọ eji ọgwụ Tujo SoloStar® mee ihe

A na-etinye tujeo SoloStar® n'ime abụba dị n'okpuru nke afọ, ubu ma ọ bụ n'úkwù. Ebe ndị irighiri ahụ kwesịrị iji ụzọ ọzọ dị mkpa dochie ụzọ maka ọgwụ nchịkwa.

Tujeo SoloStar® abụghị maka nhazi nchịkwa. Ogologo oge insulin glargine na-ahụ maka ọ bụ naanị mgbe ewepụtara ya n'ime abụba dị n'okpuru ala. Na / na ntinye nke sc sc na-emebu nwere ike ibute nnukwu hypoglycemia. Tujeo SoloStar® abụghị maka iji insulin infusion pump.

Tujeo SoloStar® bụ ihe doro anya, ọ bụghị nkwụsị, yabụ ịmaliteghachị tupu iji ya abụghị ihe achọrọ.

- Mpempe nkwụghachi nke mkpụrụ okwu Tujeo SoloStar shows na-egosi ọnụọgụ nke Tujeo SoloStar® nke a ga-elekọta. Emeela Tujeo SoloStar® Syringe Pen ka emepụtara nke ọma maka nkwadebe Tujeo SoloStar®, yabụ enweghị ntụgharị ọzọ achọrọ,

Ofzọ nke ngwa

A na - ahụ ọgwụ insulin site na ntụtụ dị n'okpuru ala. Enwere ike iji "Tujeo SoloStar" n'agbanyeghị nri. Maka arụmọrụ ka ukwuu, a na-atụ aro ịgbanye n'otu oge n'ụbọchị. Ndidi - 3 awa. Onye ọrịa ahụ nwere ihe ruru elekere 6, n'oge ọ ga-enye ọgwụ insulin ọzọ. N'okwu a, ị gaghị atụ egwu nke ima elu dị n'ọbara shuga.

Enwere ike ịchọ ndozi usoro usoro ọgwụgwọ maka:

• gbanwee nri
• na-agbanye na ọgwụ ọzọ ma ọ bụ onye nrụpụta.
• mmepe nke ọrịa ma ọ bụ nsogbu nke ọrịa shuga,
• gbanwee ụdị obibi ndụ: nrụgide anụ ahụ ma ọ bụ nke mmetụta uche.

Ọbara site na usoro a ga - ekpebi site na onye na - abịa endocrinologist. Tupu ịmalite usoro ọgwụgwọ insulin, dị njikere ịgụ ntuziaka ahụ. A na-ewepụta “Tujeo SoloStar” otu ugboro n'ụbọchị.

Ekwesịrị itinye insulin n'ime anụ ahụ dị n'okpuru mpaghara nke mgbidi akụkụ ihu, apata ụkwụ, ma ọ bụ akwara ubu olu dị elu. Site n'oge ruo n'oge, ọ dị mkpa ịgbanwe saịtị ntinye. Iji mkpịsị sirinji ejiri otu, ị nwere ike banye n’echekwa 1 ruo 80 kwa oge 1. Ngwaọrụ a nwere tebụl pụrụ iche na-enye gị ohere ịhọrọ ogo insulin chọrọ. Iji zere ọrịa ndị na-efe efe, a na-atụ aro sirinji iji maka ọgwụgwọ naanị otu onye ọrịa.

Iji gbochie hypoglycemia dị ukwuu, ejila sirinji mgbe ọ bụla si na katriiki were ngwaahịa a. Gaghị enwe ike ịchọpụta ụda nke homonụ nke ọma, dịka nsonazụ enwere ike ime. A na-eji agịga ahụ naanị oge 1. Mgbe ogwu ogbugba ahụ gasịrị, a ga-ewepụ ya ma jiri ya na-adịghị mma. Igha ọzọ na agịga ga-eduga na mgbochi ya. N'aka nke a, a na - ebute nsogbu nke inye insulin obere ma ọ bụ nke buru ibu.

Tupu usoro a, gbaa mbọ hụ na ihe edozi ahụ doro anya, enweghị ikuku ikuku. Mee nnwale maka ahụike nke mkpụrụ sirinji na ọnọdụ nke agịga ahụ: pịa bọtịnụ ịbanye - ihe kwesịrị ịpụta n'ọnụ ọnụ agịga ahụ. Mgbe nke ahụ gasị, ị nwere ike mezuo usoro ahụ.

A na-eji Tujeo SoloStar mee ihe maka ụdị ọrịa shuga 1 nke ọrịa mellitus na njikọ insulin dị mkpụmkpụ. N'ime ụdị ọrịa 2, a na-enye ya ọgwụ dịka monotherapy ma ọ bụ na njikọta ya na ndị nnọchi ọgwụ antidiedi. Ngozi a tụrụ aro maka ụdị shuga 2 bụ 0.2 kilogram 1 maka ịdị ahụ ya.

Difọdụ ndị ọrịa mamịrị na-esi Lantus na-aga SoloStar. Nke mbu, were ogwu a 1: 1. N’ọdị n’ihu, a na-ahọrọ oke kachasị mma. Mgbe ị na-agbanwe site na Lantus na 100 PIECES nke glargine, a na-ebelata dose ahụ site na 20%.

Mgbe odi nkpa, enyere SoloStar maka ndi di ime. Dika odi, n’ime oge mbu, a choro ikwusi ike nke insulin, n’ime oge nke abuo na nke ato o na abawanye. N'oge a na-enye nwa ara, enwere ike ịchọ mgbanwe maka oke ọgwụ ahụ. Ọ bụ dọkịta ga-ekpebi usoro usoro onunu ogwu.

N'oge usoro ọgwụgwọ insulin, ịkwesịrị iji nyochaa usoro nke glucose dị n'ọbara.

A na-adụ ndị ọrịa shuga ọdụ ka ha na ngwaọrụ ha nwere mgbe niile - ọ bụrụ na nke bụ nke mebiri emebi. Mgbe ogwu ogbugba izizi sitere na sirinji, enwere ike iji ya karịa ọnwa 1. Na-echekwa n'ebe kpọrọ nkụ nke anwụ na-achaghị ọcha na-acha ọkụ na okpomọkụ nke +2 ... +8 о С.

Nsonaazụ

N'ọnọdụ ndị pụrụ iche, Tujeo SoloStar nwere ike ibute mmeghachi omume na-achọghị.

N'oge ọgwụgwọ, enwere ike ịme mmetụta ụfọdụ.

• Usoro nke metabolism: hypoglycemia - ọnọdụ na - eme mgbe ị na - eri insulin nke ukwuu karịa anụ ahụ chọrọ. Enwere ike ịnwe ike ọgwụgwụ, iro ụra, isi ọwụwa, ọgba aghara, nsogbu.
• Organs: imebi turgor na lend refractive index. Ọrịa dị mkpirikpi, adịghị achọ ọgwụgwọ. N’oge na-adịghị anya, ọhụụ na-adịte aka.
• Akpụkpọ anụ na anụ ahụ: subpodystrophy na mmeghachi omume mpaghara na mpaghara nchịkwa. Achọpụtara ya naanị na 1-2% nke ndị ọrịa. Iji gbochie nrịba ama a, ịkwesịrị ịgbanwe saịtị ntụtụ.
• Ihe mgbochi: sistemu na-emetụta ụdị edema, bronchospasm, iwetulata ọbara mgbada, ujo.
• Mmeghachi omume ndị ọzọ: ọ na-esiri ahụ ike ịmalite ịnabata insulin, na-akpụ ọgwụ mgbochi ụfọdụ.

Iji gbochie nsonaazụ ọ bụla, a na-adụ onye ọrịa ọdụ ka o nyocha ya nke ọma. Soro usoro ọgwụgwọ dọkịta gị nyere gị mgbe niile. Medication medicationụ onwe gị ọgwụ nwere ike itinye ndụ gị n'ihe egwu.

Mkparịta ụka ọgwụ ọjọọ

Groupsfọdụ ọgwụ ọgwụ metụtara metabolism metabolism. Ọ bụrụ na ọ dị mkpa, ịnabata ọgwụ ọnụ na data Tujeo SoloStar chọrọ ka ọ gbanwee insulin.

Ọgwụ hypoglycemic ọgwụ, ACE inhibitors na MAO, salicylates, fluoxetine, pentoxifylline, propoxyphene, sulfonamides nwere ike ịbawanye hypoglycemic mmetụta nke insulin. N'okwu a, ihe ize ndụ nke ịmalite hypoglycemia na-abawanye.

Corticosteroids, danazole, diazoxide, diuretics, sympathomimetics, glucagon, ihe ndị a na-ahụ anya phenothiazine, ndị na-egbochi nchebe na ọgwụ na-adịghị ala ala nwere ike ịkụda ike hypoglycemic nke Tujo SoloStar.

Ndị na-eme ọgwụ Beta-blockers, clonidine, salhi lithium na ethanol na-enwe ike ịkwalite ma ọ bụ na-akụda mmetụta nke ọgwụ ahụ.

Na mgbakwunye na pentamidine, nsogbu nke hypoglycemia na-abawanye, nke nwere ike ịghọ hyperglycemia.

Na mgbakwunye na beta-igbochi, clonidine, guanethidine na reserpine, mgbaàmà ma ọ bụ akara nke nzaghachi ụjọ nke etiti na-eme ka mmepe nke hypoglycemia nwere ike ma ọ bụ ghara ịdị.

Mgbe ejikọtara ya na pioglitazone, nkụda obi na-ebilite mgbe ụfọdụ.

Tujeo SoloStar bu nkwalite insulin nke di elu nke natara otutu nyocha site n’aka ndi dibia na ndi oria. Ọ na-ebelata ihe egwu nke nsogbu site na sistem akwara, eriri afọ na akwara dị n’etiti ndị ọrịa mamịrị. N'oge usoro ọgwụgwọ, onye ọkachamara kwesịrị ilebara onye ọrịa ahụ anya.