Bioulinnthetic insulin Humulin: ọnụahịa nke ụdị ntọhapụ nke ọgwụ na nuances nke iji ha

Aha ahia: Humulin Regular

Aha International nonproprietary: Ngwọta insulin (injinị mkpụrụ ndụ mmadụ)

Usoro onunu ogwu: ngwọta ntụtụ

Bekee arụ ọrụ: insulin na-anọpụ iche soluble biosynthetic mmadụ

Otu na-ere ọgwụ: insulin mmadụ na-eme mkpụmkpụ

Mlọ ọgwụ: Nnukwu insulin nke mmadụ na-eme n’onwe ya. Ọ bụ nkwadebe insulin na-eme obere oge. Isi mmetụta nke ọgwụ bụ iwu nke glucose metabolism. Na mgbakwunye, o nwere mmetụta anabolic. Na akwara na akwara ndị ọzọ (ewezuga ụbụrụ), insulin na - ebute ọsịsọ glucose na amino acid na - eme ngwa ngwa intracellular. Insulin na - akwalite ntụgharị nke glucose na glycogen na imeju, na - egbochi gluconeogenesis ma na - akpali ntụgharị nke oke glucose na abụba. Mmalite nke ị theụ ọgwụ ahụ bụ nkeji 30 mgbe nchịkwa gasịrị, mmetụta kachasị n'etiti awa 1 na 3, oge nke ime ihe ahụ bụ awa 5-7.

Ihe ngosi maka ojiji:

Ọrịa shuga mellitus nwere ihe ngosipụta maka ọgwụgwọ insulin, ọrịa shuga mbụ mellitus chọpụtara, ịtụrụ ime nwere ụdị ọrịa shuga mellitus nke 2 (nke na-abụghị insulin).

Contraindications:

Hypoglycemia, hypersensitivity na insulin ma ọ bụ otu n'ime mmiri ọgwụ.

Usoro usoro onunu ogwu

Ọ bụ dọkịta ga-ekpebi ọgwụ ahụ n'otu n'otu, dabere na ọkwa nke glycemia. Ekwesịrị ịnye ọgwụ ahụ s / c, na / n'ime, ikekwe na ntinye / m. A na-a drugụ ọgwụ SC n'ubu, apata ụkwụ, ma ọ bụ oghere afọ ma ọ bụ afọ. Ekwesịrị ịgbanwere ebe a na-agba ọgwụ ọnụ ka ejiri otu ebe ahụ karịa ihe dịka 1 oge / ọnwa. Mgbe s / n’okwu mmeghe, a ga-elerịrị anya ka a ghara ịbanye n’ime arịa ọbara. Mgbe ogwu ogbugba gasịrị, ekwesighi ịhịa aka ntụtụ. Ekwesịrị ịzụ ndị ọrịa ka esi eji ngwaọrụ insulin eme ihe. Cartridges na vials nke Humulin Regular anaghị achọ nhazigharị enwere ike iji ya ma ọ bụrụ na ọdịnaya ha bụ mmiri doro anya na-enweghị ụcha na-enweghị irighiri ihe. Ekwesịrị iji nlezianya nyochaa katridges na vials. Shouldkwesighi iji ọgwụ ahụ ma ọ bụrụ na o nwere flakes, ma ọ bụrụ na ụmụ irighiri ihe na-acha ọcha na-agbado na okpuru ma ọ bụ mgbidi nke karama ahụ, na-ekepụta mmetụta nke usoro kent. Ngwaọrụ nke katalọgụ anaghị ekwe ka agwakọta ihe ndị dị n’ime ya na ihe ndị ọzọ dị na katriiki n’onwe ya. Edeghị Cart Cartges. Ekwesịrị ijupụta ọdịnaya nke vial ahụ na sirinji insulin nke kwekọrọ na mkpokọta insulin na-achịkwa, yana ọgwụ insulin chọrọ ka dọkịta nye ya kwesịrị ịhazi. Mgbe ị na-eji katridges, soro ntuziaka onye nrụpụta maka imeju katrij na ibanye na agịga. Ekwesịrị ịnye ọgwụ ahụ na ntuziaka nke onye nrụpụta maka mkpịsị sirinji. Iji akwa mpụta nke agịga ahụ, ozugbo ịtinye ya, yọpụ agịga ahụ ma bibie ya nke ọma. Wepu agịga ozugbo a gbasasịrị ahụ na-eme ka ọ ghara ịdị mma, na - egbochi itufu ikuku, nmalite ikuku yana ịhapụ ịchọrọ. Wee tinye okpu na aka. Ekwesighi ijigharị agịga. Ekwesighi iji ndị ọzọ agịga na pensụl. A na-eji katridges na vials ruo mgbe ha tọgbọ chakoo, emesịa a ga-atụfu ha. Enwere ike ịchịkọta Humulin Regular yana yana Humulin NPH. Maka nke a, ekwesịrị ịbanye insulin n'oge na-adịghị eme ihe n'ime sirinji iji gbochie insulin na-eme ogologo oge ịbanye na vial. Ọ dị mma ịmebata ngwakọta a kwadebere ozugbo agwakọta. Iji duzie otu ụdị insulin ọ bụla, ị nwere ike iji sirinji iche maka Humulin Regular na Humulin NPH. Youkwesịrị iji sirinji insulin na-arụkọ ọrụ ọnụ.

Mmetụta ọghọm:

Mmetụta akụkụ metụtara isi mmetụta nke ọgwụ: hypoglycemia. Nnukwu hypoglycemia nwere ike ibute ọnwụ na (n'ọnọdụ ụfọdụ) ọnwụ. Mmeghachi omume nfụkasị: mmeghachi omume nfụkasị mpaghara enwere ike - hyperemia, ọzịza ma ọ bụ itching na saịtị ịgba ahụ (na - akwụsịkarị n'ime oge ọtụtụ ụbọchị ruo ọtụtụ izu), mmeghachi omume nfụkasị usoro (na - erughị oge, mana ọ ka njọ) - itching juputara, mkpụmkpụ ume, mkpụmkpụ ume , mgbada ọbara na-ebelata, obi mgbali elu, ịba ụba aja. Ọnọdụ siri ike nke mmeghachi omume nfụkasị systemic nwere ike igbu mmadụ. Ihe ozo: o nwere ike di obere irighiri ahihia.

Mmekọrịta na ọgwụ ndị ọzọ:

A na-ebelata hypoglycemic mmetụta nke Humulin Regular site na mgbochi mgbochi ọnụ, corticosteroids, nkwadebe homonụ thyroid, thiazide diuretics, diazoxide, antidepressants tricyclic. A na-eme ka mmetụta hypoglycemic nke Humulin Regular nke ọgwụ ọgwụ hypoglycemic nke na-ahụ ike, salicylates (dịka ọmụmaatụ, acetylsalicylic acid), sulfonamides, MA inhibitors, beta-blockers, ethanol na ọgwụ ethanol nwere. Beta-mgbochi, clonidine, reserpine nwere ike kpuchie ngosipụta nke ọrịa hypoglycemia. Nnyocha ọmụmụ ọgwụ: nsonaazụ nke ịgwakọta insulin mmadụ na insulin anụmanụ ma ọ bụ insulin mmadụ mepụtara site na ndị nrụpụta ndị ọzọ.

Bọchị mmebi: Afọ 2

Ọnọdụ nke izipu ọgwụ site na ụlọ ahịa ọgwụ: site na ndenye ọgwụ

Emeputa: Eli Lilly East S.A., Switzerland

Mpempe mwepụta

Ọ dị mkpa iburu n'uche na ihe na-arụ ọrụ n'ime ọgwụ bụ insulin biosynthetic mmadụ. A na-ahapụ ọgwụ ahụ n’ụdị nkwụsị maka injection na azịza pụrụ iche maka inje. Typesdị ndị a nwere ike ịbụ ma na katridges, na karama.

Insulin Humulin N

Emeputa

Ikwesiri ichoputa onye egosiri insulin? Usoro ọgwụgwọ maka ndị nwere ụdị ọrịa shuga agaghị ezu ezu ma ọ bụrụ na analogue insulin bụ mmadụ. Ọ dị mkpa iji nọgide na-enwe n'ọtụtụ shuga n'ọbara n'ime ókè a kpaara ya ike.

A na-eji ọgwụ ọzọ eme ihe iji kwalite ọnọdụ ndị ọrịa na ọrịa a. Banyere mba ndị mepụtara, a na-enwekarị atọ ma ọ bụ anọ n'ime ha. Ebe enwere ọtụtụ ụdị ọgwụ a, a na-emepụta nke ọ bụla n'ime mba dị iche iche.

N'oge a, ụdị ọgwụ ọgwụ a na-achọ iche na-egosi na ọgwụ ọgwụ:

1. Humulin NPH (USA, France),
2. Humulin MZ (France),
3. Humulin L (USA),
4. Humulin Regular (France),
5. Humulin M2 20/80 (USA).

Ihe nhazi insulin nile dị n’elu (hormone a na-eme ka pancreatic) nwere mmetụta hypoglycemic (hypoglycemic). Emepụtara ọgwụ a dabere na insulin nke inyocha mkpụrụ ndụ ihe nketa mmadụ.

Ọrụ bụ isi nke Humulin bụ ibelata ọkwa glucose na ọbara. Yabụ, ọgwụ ahụ na-enye ume ọrụ n'ụdị shuga site n'ụdị anụ ahụ ma na-etinye ya na usoro metabolic na-eme na sel nke ahụ.

Dabere na usoro nkwadebe na nhazi nhazi, insulin ọ bụla nwere njiri mara nke ya, nke a na-eleba anya na nhọpụta ọgwụgwọ pụrụ iche. Na mgbakwunye na akụrụngwa bụ isi nọ na ya (insulin, nke a tụrụ na mpaghara mba - ME), ọgwụ niile na-agụnye nchịkọta ndị ọzọ sitere na aka mmadụ.

Dịka iwu, enwere ike itinye ihe ndị dị ka protamine sulfate, phenol, zinc chloride, glycerin, metacresol, sodium hydrogen phosphate, sodium hydroxide, hydrochloric acid, mmiri maka injection na ndị ọzọ nwere ike itinye ya na ụdị Humulin ọ bụla.

Ọgwụ a na-enyere aka nweta ezigbo nsonaazụ site na ọgwụgwọ. Nke a bụ n'ihi na ọ nwere ike ime ka enwee ike zuru oke ma ọ bụ nwee akụkụ nke mmetụta nke insulin homonụ.

Ọ dị mkpa icheta na a ga-enyerịrị ọgwụ ọgwụ a naanị site na endocrinologist. Na-esote, mgbe nsogbu dị ngwa bilitere, naanị dọkịta kwesịrị ịnagide usoro enyere ọgwụ ahụ.

Mgbe mgbe, itinye insulin akpọrọ Humulin na-ebi ogologo ndụ. Ogologo oge dị otú a, edere ya na ọnụnọ nke ụdị ọrịa shuga 1.

N'ọnọdụ ụfọdụ (ya na ọrịa na-efe efe na-apụta n'ụdị akwara ma ọ bụ nke na-adịghị ala ala, yana ọnọdụ na-arịa ọrịa shuga na ọrịa nke ụdị nke abụọ), a na-atụ aro itinye usoro ọgwụgwọ nke ọnwu dị iche iche.

Echefula na ọrịa shuga chọrọ oge a ga-ahọpụta homonụ na-eme ka mmadụ sie ike.

Ọ bụ ya mere ijupụ ya nwere ike iji kpata nsonaazụ na-enweghị atụ maka ahụike mmadụ.

Ugbu a, ndị kachasị emetụta na nke a bụ ụdị ọgwụ dị ka Humulin Regular na Humulin NPH.

Dabere na iche iche, enwere ike ịzụta ọgwụ Humulin na ụdị a:

1. NPH. Enwere ya dị ka nkwusioru maka nchịkwa subcutaneous, 100 IU / ml. A kwakọtara ya na karama dị milimita iri na iko na anọpụ iche. A na-akwakọba ibe ha n’ime igbe kaadi. A na-akwakọkwa ụdị ọgwụ a na katridges milimita atọ nke iko yiri ya. Ise n'ime ndị a na-etinye na ọnya. Onye ọ bụla n'ime ha dabara na ngwugwu pụrụ iche,
2. MH. Ọ dị n'ụdị mgbapụta ndị a: nkwusioru maka ntụtụ (3 ml) na katriji ndị pụrụ iche, nkwusioru (10 ml) na karama, ntụtụ ntụtụ (3 ml) na katriji, ihe ngwọta (10 ml) na karama,
3. L. Nkwụsị maka ntụtụ 40 IU / ml ma ọ bụ 100 IU / ml n'ime karama 10 ml, nke a na-etinye na mkpọchi kaadiboodu,
4. Mgbe. N'otu aka ahụ na nke gara aga, a na-emepụta ya na oke, 1 ml nke nwere 40 PIE MES ma ọ bụ 100 PIECES,
5. M2 20/80. Mwepu ntụtụ ahụ nwere insulin mmadụ 40 ma ọ bụ 100 IU / ml. Ọgwụ ahụ dị na karama na katriiki.

Ọrịa shuga na-atụ egwu ọgwụgwọ a, dị ka ọkụ!

Naanị ịchọrọ itinye ...

Banyere ọnụ ahịa ahụ, ụdị ọgwụ ọ bụla a na-eche na ha nwere ọnụahịa nke ya.

Ọ bụrụ na nkọwa zuru ezu, mgbe ahụ ndepụta ndepụta nke Humulin dị ka ndị a:

1. NPH - dabere na usoro onunu ogwu, onu ahia di 200 rubles,
2. MH - ọnụ ego ruru ihe dị ka 300 ruo 600 rubles,
3. L - n'ime narị rubles anọ,
4. Mgbe - ruru 200 rubles,
5. M2 20/80 - site na 170 rubles.

Ofzọ nke ngwa

A na-enyekarị Humulin ihe n'ụzọ ga - eme ka nri diges kwụsị. A na-enyekarị gị irighiri akwara ma ọ bụ nke dị n'okpuru ala.

Dịka iwu dị adị, onye ọrịa endocrinologist ga-anata ọzụzụ ọzụzụ pụrụ iche, dịka ọmụmaatụ, n'ụlọ akwụkwọ "ọrịa shuga".

Ego ole ọgwụ a chọrọ kwa ụbọchị, ọ bụ naanị dọkịta na-ahụ maka ya ga-ekpebi. Usoro ahọpụtara ahọrọ nwere ike ịdị iche dabere n'ụdị mmega ahụ na nri nri. Ọ dị ezigbo mkpa ka onye ọrịa nke endocrinologist na-achịkwa ọkwa nke glycemia.

Dịka iwu, ekwesịrị ị drugsụ ọgwụ insulin na-eme kwa ụbọchị. Ọgwụ a dịkwa irè maka ma ụmụ nwoke ma ụmụ nwanyị.

Ndị dọkịta kwuru na ụmụaka nwere ike iji Humulin mee ihe. N'ezie, ọ bụrụ na a na-achịkwa glycemia n'oge eji. Ndị okenye kwesịrị iji nlezianya nyochaa ọrụ nke akụkụ ahụ nke usoro ahụ. Dịka iwu, ndị dọkịta ka etinyere ọgwụ dị ala maka ndị ọrịa dị otú a.

N’oge ime ime, a nwekwara ike iji ọgwụ ndị a. A na-ahapụ ọgwụ ndị ọzọ dabere na insulin, ihe yiri nke mmadụ, maka inye ara.

Nsonaazụ

Humulin nke ụdị dị iche iche nwere otu mmetụta ahụ, nke edepụtara na ntuziaka maka ya.

O yikarịrị bụ na dochie anya insulin mmadụ nwere ike iduga lipodystrophy (na mpaghara ebe a gbanyere ntụtụ).

Ọbụna na ndị ọrịa nwere endocrinologists, megide ndabere nke iji ọgwụ a, insulin resistance, allergies, mbelata nke potassium n'ime ọbara, na nkwarụ anya.

Enwere ike ịmeghachi ihe nfụkasị ahụ site na homonụ nke pancreas, kama site na ọgwụ ndị ọzọ nke ọgwụ ahụ, ya mere, a na-anabata ọgwụ iji dochie ọgwụ ọzọ yiri ya.

Ihe ngbanwe

Ọgwụ a na-a isụ ọgwụ ka enyere ya ọgwụ mgbochi ọrịa mellitus na-agbanwe insulin.

Ọ dị mkpa ịkpachapụ anya, ọkachasị ma ọ bụrụ na a hụrụ hypoglycemia (shuga dị ala).

A machibidoro ọgwụ ọzọ iji mee ihe n'ihu mmadụ (n'ihi na ọ nwere ike ime ka mmeghachi omume nfụkasị ahụ na-adịghị mma). Ndị ọkachamara machibidoro ị ofụ mmanya na-aba n'anya n'oge ọgwụgwọ a ụdị insulin. Nke a bụ n'ihi na mgbanwe dị oke agbanwe na ọkwa glucose ọbara dị.

Tupu iji ya, ịkwesịrị ị attentiona ntị na ọgwụ ị na-a atụ n'oge. Themfọdụ n’ime ha ekwekọghị na Humulin.

Vidiyo ndị metụtara

Banyere ojiji nke ọgwụ Humalog, Novorapid, Lantus, Humulin R, Insuman-Rapid na Actrapid-MS maka ụdị shuga 1:

Isiokwu a na-enyocha homonụ nke pancreas nke sitere na aka mmadụ, nke ya na insulin mmadụ nwere - Humulin. Ekwesịrị ịbanye ya naanị ma ọ bụrụ na dọkịta depụtara ya na nyocha ahụ.

Wezuga ọgwụ a na-akwụghị ọtọ, ebe ọ bụ na enwere ike ịhụ mmeghachi omume nke anụ ahụ. Na mgbakwunye, ọgwụ a anaghị enye ndị ahịa ọgwụ na-enweghị ndenye ọgwụ nke dọkịta na-agwọ onwe ya.

Pharmacodynamics na pharmacokinetics

Humulin NPH bụ Ihe nnabata DNA na - eme mmadụ insulin ya na oge iji gosipụta mkparịta ụka, isi ihe dị na ya bụ ịhazi ihe glucose metabolism. Ọgwụ na-egosikwa anabolic ịdị irè.

N'ime anụ ahụ nke mmadụ (ewezuga akwara ụbụrụ), insulin Humulin NPH na-eme ka ebugharị ebugharị amino acid na glucose, na-emekwa ka usoro ya dị ọkụ anabolism protein. Yiri na imeju, ọgwụ na-akwalite nguzobe nke glycogensite na glucosena-akpali mgbanwe nke njuputa glucosen'ime abụbamgbochi gluconeogenesis.

A na - ahụta mmalite nke insulin Humulin NPH nkeji 60 mgbe nlekọta nchịkwa, na arụmọrụ kachasị na oge ahụ site na awa 2 ruo 8 na oge nke ime n'ime awa 18-20.

Hụrụ ndị iche iche na arụmọrụ insulindabere na nhọrọ ị doseụ ọgwụ, saịtị ịgba ọgwụ, yana ọrụ anụ ahụ nke onye ọrịa.

Ihe ngosi maka ojiji

E gosipụtara ọgwụ Humulin NPH maka iji:

• mbụ emee ya ọrịa shuga,
• ọrịa shugabụrụ nke na-egosi nhọpụta ọgwụ insulin,
• nke afọ imena ndabere na-arịa ọrịa shuga na-abụghị insulin (ụdị 2).

Nsonaazụ

Mmetụta dị n'akụkụ bụ hypoglycemia, nke n’ihe banyere oke ọrụ nwere ike ibute nsụhọ na ọbụna ọnwụ (adịkarịghị).

Enwekwara ike di otua lipodystrophy.

Ihe ngosipụta anwansị nke ọdịdị dị n'ụdị:

Ihe ngosipụta anwansị nke ọdịdị mpaghara:

• ọzịzama obu itchingna mpaghara ịgba ogwu (na-akwụsịkarị n'ime izu ole na ole),
• hyperemia.

Ntuziaka maka iji Humulin NPH

A họrọ usoro ọgwụ Humulin NPH n'otu n'otu, dabere na ọkwa nke glycemiaonye ọrịa.

Amachibidoro inje intulin nke Humulin NPH!

Ekwesịrị iji aka emulsion ahụ mee, mgbe ụfọdụ, a na-ahapụ inje IM. A na-eme nchịkwa subcutaneous n'ime afọ, ubu, ike ma ọ bụ apata ụkwụ. Ekwesịrị ịgbanwere ebe a ga-agba ntụtụ ka ụbọchị iri atọ ọ bụla agaghị agbafe otu ebe.

Ntugharị SC chọrọ ụfọdụ ọrụ maka njikwa na ịkpachara anya. Ọ dị mkpa izere ịbanye na agịga n'ime arịa ọbara, ọ bụghị ịhịa aka n'ahụ ebe a na-agba ya, yana ijikwa ngwaọrụ ndị na-eji ọgwụ ahụ nke ọma.

Nkwadebe na nhazi nke Humulin NPH

Na ebumnuche nnweta insulin, tupu iji ya, a na-atụ aro vials na katridges nke Humulin NPH ịkwado ugboro 10 n'ọbụ aka gị ma maa jijiji otu oge ugboro (tụgharịa 180 Celsius) ruo mgbe nkwadebe ahụ ga-enweta ọnọdụ nke agba mara mma na mmiri ara ehi ma ọ bụ mmiri na-agakọ. Kingkagbu ọgwụ ahụ ike ekwesịghị ịdị, ebe ọ bụ na ụfụfụ guzobere n'ụzọ a nwere ike igbochi kpọmkwem nhọrọ nke dose ahụ.

A ga-eji nlezianya nyochaa vials na katriji. Zere iji insulineji ogwe osisi na-acha uhie uhie ma ọ bụ nke na-acha ọcha na-agbada na mgbidi ma ọ bụ na karama nke karama ahụ, na-akpụ echiche nke usoro ntu oyi.

Ihe okike n’aputa ihe anaghi eme ka ihe ya di nma na ndi ozo insulin, yana ị na-emejupụta katọn ahụ n'onwe ya.

Mgbe ị na-eji vials, a na-anakọta emulsion na nke ahụ sirinji insulin, nke na olu kwekọrọ na ntinye insulin(dịka 100 IU / 1 ml insulin= Sirinji 1 ml) ma jikwa ya na ntinye nke dọkịta.

Mgbe ị na-eji katriji dị iche iche, ọ dị mkpa ịgbaso ndụmọdụ nke onye mepụtara sirinji mkpịsị maka ịwụnye ha, na-ejide agịga, ma na-achịkwa insulin, dịka ọmụmaatụ, ntuziaka maka Humulin NPH na mkpịsị Pen Pen Ndenye.

Ngwa ngwa ozugbo, iji mpụta nke agịga, wepụ agịga ahụ n'onwe ya ma bibie ya n'ụzọ adịghị mma, wee jiri okpu ahụ mechie aka ahụ. Usoro a na-enyekwu ikike, na-egbochi ikuku ịbanye, na-egbochi ịhapụ ọgwụ ahụ na ịhapụ ịlogụ ọgwụ ọ bụla.

Ekwesighi iji ndị ọzọ mee ihe ma ọ bụ jiri mkpịsị mkpụrụ osisi sirinji. A na-eji vials na katridges otu oge ruo mgbe ọgwụ a gwụchara, wee tụfuo.

Ikekwe iwebata Humulin NPH yana Humulin Regular. Maka gịnị, iji gbochie ịbanye na karama ahụ insulinime ihe dị ogologo, onye izizi ị banye na sirinji insulinobere ihe. A na-atụ aro ka ịmebata ngwakọta a ozugbo agwakọta. Maka ezigbo usoro ọgwụgwọ abụọ insulinnwere ike iji sirinji dị iche iche.

Dodoụbiga ya ókè

Dika odi, ogweghi otutu ogwu nke Humulin NPH. A na-ahụta ọrịa dị ka ngosipụta. hypoglycemiasonyere ụba ọsụsọiju tachycardiaisi ọwụwa pallor akpụkpọ integument ịma jijiji, ndabavomiting.

N'ụfọdụ, mgbaàmà ndị na-ebute hypoglycemia (ọrịa shuga dị ogologo ma obu ike ya nwere ike) gbanwe.

Nkowasi hypoglycemiadị nro, site na nchịkwa ọnụ na-akwụsị shugama obu glucose(dextrose) N’ọdịnihu, inwere ike ịgbanwe ụdị nri ị na-eri insulinma ọ bụ mmega ahụ.

Imeghari hypoglycemiaAna-eburu ibu dị nfe site na SC ma ọ bụ ntụtụ / m glucagon, na nchịkwa ọnụ na-aga n'ihu carbohydrates.

Ngosipụta nke oke hypoglycemiaenwere ike sonye Coma, nsogbu akwara ozi ma obu mmasinke a na-eji ntụtụ env dị glucose gbadoros (dextrose) ma ọ bụ s / c ma ọ bụ na ntinye / m glucagon. N'ọdịnihu, iji gbochie nlọghachi nke mgbaàmà, nri nke ọgaranya carbohydrates.

Mmekorita

Podị Hypoglycemic nke Humulin NPH na-ebelata site na iji concomitant ogwu gboro yahomonụ thyroid glucocorticoids, thiazide diureticstricyclic antidepressants, Diazoxide.

Ngwa ijikọtara ethanolọgwụ hypoglycemic (onu), salicylatesMA inhibitors sulfonamides, ihe mgbochi beta welie mmetụta hypoglycemic nke Humulin NPH.

Ntụziaka pụrụ iche

Kpebie mkpa ọ dị inyefe onye ọrịa ọgwụ ma ọ bụ ụdị ọzọ insulin enwere ike ịbụ dọkịta. Mgbanwe a kwesịrị ịmalite n'ọnọdụ nchịkwa nke ọnọdụ onye ọrịa ahụ.

Changedị mgbanwe ọrụ insulin(Mgbe obula, M3wdg), njikọ nke umu ya (mmadu, anụ ezi, analog) ma ọ bụ usoro mmepụta (anumanumbido ma ọ bụ Ntughari DNA) nwere ike ịchọ mmegharị dose, ma na nchịkwa izizi na n'oge ọgwụgwọ, nke nta nke nta karịa izu ma ọ bụ ọnwa.

Insulinịdabere nwere ike ibelata gbasara akwarapituitary gland gren adrenalgland thyroid imeju.

Na obi erughị ala na ụfọdụ ọrịa, enwere ike ịchọrọ maka ya insulin.

Oge ụfọdụ idozi usoro ọgwụgwọ kwesịrị ekwesị mgbe ị na-agbanwe nrima ọ bụ mụbaa mmega ahụ.

Na ụfọdụ ndị ọrịa, ọ bụrụ na ejiri ya insulin mmadumgbaàmà bu ụzọ hypoglycemiaenwere ike ịdị iche na nke ndị mmadụ mgbe ị na-eji ya anụmanụ insulin ma ọ bụ belata akpọ.

Nkịtị plasma ọkwa glucosen'ihi kpụ ọkụ n'ọnụ ọgwụ insulinna-eduga na nghọpụ nke ihe niile ma ọ bụ ụfọdụ ngosipụta hypoglycemiaihe ịchọrọ ịgwa onye ọrịa.

Ihe mgbaàmà nke mmalite hypoglycemiaenwere ike wedata ma ọ bụ gbanwee ma ọ bụrụ na iji ya ọzọ mee ihe ihe mgbochi beta, ọrịa mamịrị na-arịa ọrịa mamịrịma ọ bụ ogologoọrịa shuga mellitus.

N'ụfọdụ, mpaghara nfụkasịIgosiputa ihe nwere ike itolite maka ebughi oke nsogbu nke ogwu a (dika ima atu, akpukpo anụ n'ihi iji ihe nhicha ma ọ bụ ọgwụ na-ekwesịghị ekwesị).

N’oge na-adịghị anya, mmeghachi omume nfụkasị sistemụ nwere ike ịchọ ọgwụgwọ ozugbo (eduzi enweghị nchekasịma obu nnọchi insulin).

N'ihi mgbaàmà enwere ike hypoglycemiaEkwesịrị ịkpachara anya mgbe ị na-arụ ọrụ dị ize ndụ ma na-anya ụgbọ ala.

• Ihe mberede insulin-Ferein,
• Monotard HM,
• Insulin-Ferein ChSP,
• Monotard MC,
• Humodar B,
• Pensulin SS.

• Vozulim-N,
• Biosulin N,
• Humulin M3,
• Gansulin N,
• Insuman Bazal GT,
• Gensulin N,
• Humulin Regular,
• Insuran NPH,
• Rinsulin NPH,
• Protafan HM,
• Humodar B 100 Osimiri.

Usoro nlekọta, usoro onunu ogwu na onu ogugu inje dị iche iche bụ nke ndị dibia bekee kpebiri n'otu n'otu.

N’ime ime (ma lactation)

Ndị ọrịa nwere ọrịa shugagwa onye nlekọta ahụike gbasara ịme atụmatụ ma ọ bụ ihe omume nke afọ ime, dị ka ọ dị na mbụ, mkpa maka insulinna-agbadata na ọkara nke mbụ ma na-abawanye na ọkara nke abụọ na nke atọ (agba agba nwere ike ịdị mkpa insulinna idozi uzo ozo).

Ọzọkwa, enwere ike ịchọ nhazi nri na / ma ọ bụ dozie oge a lactation.

Mgbe ị na-ahọrọ insulindọkịta ga-elele ọnọdụ onye ọrịa ahụ n'akụkụ niile enwere ike ịhọrọ ọgwụ dabara adaba maka ndị ọrịa a.

N'okwu a, ọgwụ Humulin NPH na-egosi nsonaazụ ọgwụgwọ dị mma ma enwere ike iji ya were ogologo oge.