Ọrịa shuga mellitus na ọgwụgwọ ya

Mgbapụta Calmette-Guerin, ma ọ bụ kama nke BCG, nke a na-eji maka ịgba ọgwụ mgbochi megide ụkwara nta, gosipụtara nsonaazụ ya n'ọrịa shuga afterdị 1 ka emechara afọ atọ. N'ime afọ ise sochirinụ, ndị ọrịa nwere ihe dị ka ọ̀tụ̀tụ̀ shuga dị n'ọbara nkịtị. Ha nile were uzo ogwu abuo nke BCG.

Otu ndi nyocha na achlọ Ọgwụ Massachusetts kwenyere na nsonaazụ nke ọgwụ a dabere na usoro metabolism nke na-enyere sel aka iri glucose. Eziokwu ahụ bụ na ọgwụ mgbochi TB na-eme ka mkpụrụ ndụ ihe nketa na-arụ ọrụ maka njikọ nke mkpụrụ ndụ Tregs. N’ihi ya, ọnụ ọgụgụ mkpụrụ ndụ ndị a na-amalite itolite n’ahụ́ ndị ọrịa mamịrị, ha na-egbochikwa T-lymphocytes n’ibibi pancreas.

Denise Faustman, onye isi dibia bekee, onye isi ụlọ nyocha nke ụlọ ọgwụ immunobiological dị na Massachusetts kwuru na enwere ike belata ọkwa shuga dị n'ọbara nkịtị ka ọ bụrụ ọkwa nkịtị. Ndị ọrụ nyocha amamịghe banyere usoro nke usoro onunu ogwu si eme mgbanwe na-adịgide adịgide n’usoro ahụ ọ na - alụso ọrịa ọgụ ma belata ọkwa shuga.

N’uche ya, nke a sitere na mmekọrịta dị n’akụkọ ihe mere eme na ogologo oge dị n’etiti ihe na-akpata ụkwara nta na ahụ mmadụ, nke dịrị kemgbe ọtụtụ puku afọ.

Ọmụmụ ihe belatara ọkwa shuga site na ihe karịrị 10% afọ atọ ka ọgwụgwọ gasịrị, yana karịa 18% mgbe afọ anọ gasịrị.

Ndị ọrụ nyocha chọpụtakwara na ọgwụ mgbochi nwere ike belata ọkwa shuga dị n'ọbara, ọ bụghị mwakpo sitere na mwepu onwe ya. Nke a na - eme ka enwere ike ịgwọ ọrịa shuga ụdị 2.

Nsonaazụ nke ulo ogwu gosipụtara na usoro a tụrụ aro ka ịgba ọgwụ mgbochi BCG nwere ike inwe mmetụta na-adịgide adịgide n’usoro ahụ ji alụso ọrịa ọgụ.

Ojiji nke ịgba ọgwụ mgbochi BCG n'ịgwọ ụdị shuga 1

Bella »Jun 27, 2011 1:53 pm

Ndewo ọrụ ọrụ! Agụrụ m ihe ederede na ozi ọma banyere ịgwọ ọrịa shuga - gịnị ghakwara ọzọ? Biko kwuo:
Ọgwụ mgbochi ụkwara nta nwere ike inye aka gwọọ ọrịa shuga na-akpata insulin. Nkwubi okwu a, mgbe ọtụtụ afọ nke nnwale gasịrị, bịakwutere ndị ọkà mmụta sayensị America.

Dabere na Haarez, ọgwụ a na - egbochi usoro ọrịa onye ọrịa ịla n'iyi. Ya mere, ahụ na-enweta ohere iji gbakee ma bido mepụta insulin nke ya.

N'ime ahụ siri ike, protein TNF na-arụ ọrụ a. Ọ na - egbochi ihe ndị ọzọ na - alụso ọrịa ọgụ bụ ihe dị ize ndụ maka pancreas. Ọgwụ mgbochi ụkwara nta, nke ejirila afọ 80 mee ka ogo nke protein a dị n’ọbara.

Akuko mbu banyere oria ogwu di otua putara n’aho iri gara aga, ma emesia nyocha ndi ozo. Ugbu a, nnyocha ndị a mere n'otu n'ime ụlọ ọgwụ Massachusetts egosipụtala usoro dị mma n'ọrịa a na ndị ọrịa na-anara ọgwụ ịgba ọgwụ mgbochi.

Nchoputa ihe omimi emere gosiputara na nzuko nke ndi otu ndi American Medical Association maka ibuso oria shuga agha.

Site na ọrịa shuga na-akpata insulin, a na-akpọkwa ya ụdị shuga 1 ma ọ bụ “nwata”, usoro ahụ ji alụso ọrịa ọgụ na-ebute “mwakpo” n'ahụ mkpụrụ ndụ akwara, bụ́ nke na-eduga n’inwe insulin zuru oke.
Ndụ ndị mmadụ na-arịa ụdị ọrịa shuga a na-adabere na inje insulin kwa ụbọchị. Ugbu a, ndị ọkà mmụta sayensị amaghị banyere ihe kpatara omume a nke usoro ahụ ji alụso ọrịa ọgụ, mana ha kwenyere na ma mkpụrụ ndụ ihe nketa na nje na-emetụta mmepe nke ọrịa shuga.

Re: Ọgwụ mgbochi ụkwara nta ga-agwọ ọrịa shuga?

li1786 June 27, 2011 2:08 PM

Re: Ọgwụ mgbochi ụkwara nta ga-agwọ ọrịa shuga?

Fantik June 27, 2011 2:58 p.m.

Nke a bụ ntakịrị nkọwa gbasara ọrụ Denise Faustman (ọzọ na Bekee): http://www.diabetesdaily.com/wiki/Denise_Faustman.

Re: Ọgwụ mgbochi ụkwara nta ga-agwọ ọrịa shuga?

Bella »Jun 30, 2011 9: 41m

Vintage "ogwu ụkwara nta nwere ike ịgwọ sd1 ??

zhenyablond »Ọgọst 12, 2012 9:10 obi

Ogwu BCG nke ndi dibia jirila nke oma
igbochi ụkwara nta maka afọ 90, ọ na-atụgharị
Ejiri ọrịa shuga Iara Ọrịa. Ndị ọkà mmụta sayensị
Mahadum Harvard mara ọkwa na enwere ike iji ọgwụ a,
ịchekwaa ndị ọrịa na-arịa ọrịa shuga ka ha ghara ịna-eme oge niile
inje insulin.

Patientsdị ndị ọrịa shuga Idị I na-anata kwa ụbọchị
shuga insulin iji mezie shuga ọbara. Nke a bụ n'ihi
enweghi ike ahu imeputa insulin n’onwe ya
ọnwụ nke mkpụrụ ndụ akwara ihe kpatara mmeghachi omume autoimmune.
Ogwu BCG na-akpali mmepụta nke protein na-emebi mkpụrụ ndụ,
na-ebute mmeghachi omume autoimmune. Ndị ọkachamara natara ụdị data ahụ
Mahadum Harvard, biputara nsonaazụ nke ihe omumu ha
na magazin PLOS Otu.

Na US naanị, nde mmadụ nde atọ na-abanye insulin kwa ụbọchị
ịchịkwa mmepe nke ọrịa gị. Ọrịa shuga Idị
chọpụtara na n’oge nwata, nke na-amanye mmadụ ime
ndu inje ine.

Ndị ọkà mmụta sayensị nke Mahadum Harvard jiri BCG gwọọ mmadụ atọ
ndị ọrịa na-arịa ọrịa shuga. N'ime ahụ ndị ọrụ afọ ofufo abụọ, imepụta insulin
gbakere. Ugbu a ndị ọkà mmụta sayensị ga-enyocha echiche ha
nnyocha buru ibu, nke a ga-eduzi ihe karịrị afọ 3-5.

Onye isi otu Denis Fostman kwuru nke ahụ
omumu ihe omuma nke oma gha buru uzo ikwusi ihe banyere BCG
ịgwọ ụdị ọrịa shuga m. Ejirilarị ọgwụ mgbochi a maka mgbochi.
ụkwara nta, yana maka ọgwụgwọ nke ọrịa kansa, nke pụtara nsogbu na
aha ya anaghi ebilite. Sayensị gosipụtara na mgbochi nke BCG
mmeghachi omume autoimmune nke na-arụ ọrụ dị mkpa na pathogenesis nke ọrịa shuga.

Denis Fostman kwuru na ndị ọkachamara Mahadum Harvard
nyere ndị ọrụ afọ ofufo atọ ọ withụ ọgwụ mgbochi BCG atọ. Ndị ọrịa
na-enyocha izu iri abụọ. Na akụrụngwa nke abụọ nke
ndị ọrụ afọ ofufo atọ belatara ọnụ ọgụgụ mkpụrụ ndụ na-akpata autoimmune
mmeghachi omume, na mmụba insulin. Maazị Fostman
kwuru na ọmụmụ ihe ahụ gụnyere ndị ọrụ afọ ofufo na-enye ọgwụgwọ
onye ndi dibia ya gwara ha na oria ha bukwara ibu
agaghị enwe ike imepụta insulin.
Bacillus Calmette-Guerin (BCG) - otu n'ime ndị okenye
ọgwụ mgbochi a ma ama n’ụwa. A kwadebere ya site na ụdị nje pathogen
ụkwara. Buputara ka eji aru oru n’ime mmadu
Paslọ Ọrụ Pasteur Paris na 1921. Ma kemgbe ahụ, a na-eji ya yana ịgba ọgwụ mgbochi ụmụaka - iji mepụta ihe mgbochi nke akwara azụ, dịka iwu, na mba ụwa nke atọ, ebe nsogbu oriri dị nnukwu.

Ndị ọkà mmụta sayensị na Harvard Medical School achọtala
na bacillus nke Calmette-Guerin nwere ike ijere mmadụ ozi ekele
ọzọ, adịghị ahụkebe, ọrụ, na-egosi ịdị irè ya
ọrịa shuga
ụdị nke mbụ - ọrịa nke na narị afọ anyị achọghị iburu ọnọdụ na
na-emetụta ọtụtụ ndị nwoke na ndị nwanyị gburugburu ụwa. Ọ tụgharịrị na BCG
na-akwalite mmepụta insulin na nje nke ndị ọrịa dị otú ahụ.

Onye ndu otu Dr. Denis
Faustman gwara ndị nta akụkọ na ndị otu ya jisiri ike site na enyemaka nke
ọgwụ mgbochi ụkwara nta na-agwọ ọrịa shuga
laabu.

Na mgbakwunye, a na-eme nyocha ụlọ ọgwụ pilot.
na - enyocha usoro ọgwụgwọ ọhụụ na ụmụ mmadụ, yana nsonaazụ ya
na-ekwe nkwa. Mgbe emechara ndị ọrụ afọ ofufo ahụ nhụsianya abụọ
doses nke ọgwụ mgbochi BCG na izu izu 4, ndị dọkịta chọpụtara nke ahụ
ọgwụ ahụ na - egbu sel nwere nsogbu "nje akwara na - amalite ịmịpụta insulin n'ime obere obere.

Yiri otu eji “vinate” ụkwara nta
ịgba ọgwụ mgbochi ọrịa, opekampe, nwere ike ịchekwa onye ọrịa mamịrị ime
inje insulin.