Etu esi eji Metformin Canon?

Ọgwụ dị n'ụdị mbadamba ihe mkpuchi-fim. Enwere mbadamba nkume nwere 500 mg, 850 mg na 1000 mg nke metformin.

Mbadamba ọgwụ nwere ọgwụ nke 500 mg bụ okirikiri, na mbadamba nkume ndị nwere usoro nke 850 mg na 1000 mg (Metformin ogologo) dị mma.

Ọgwụ dị n'ụdị mbadamba ihe mkpuchi-fim.

1. Metformin hydrochloride.
2. Polyethylene glycol (macrogol).
3. Povidone.
4. Talc.
5. Sodium stearyl fumarate.
6. Sodium carboxymethyl stachi.
7. Egwu pregelatinized.
8. Opadry II ọcha (onye na-ese ihe nkiri).
9. Titanium dioxide.
10. Polyvinyl mmanya.

Omume ọgwụ

Metformin na - egbochi gluconeogenesis, njikọ nke acids abụba n'efu, yana usoro nke Lipolysis (ndakpọ abụba) na oxidation abụba. N'otu oge ahụ, ị ​​ofụ glucose dị n'ahụ na-arụ ọrụ site na ịbawanye ụba nke sel na insulin.

Ọgwụ na-edozikwa ọdịnaya nke triglycerides na cholesterol n'ime ọbara. Enwere ntakịrị nwayọ n'ibu na ndị ọrịa buru ibu.

A na-atụ aro ọgwụ ahụ na ọnụnọ nke thrombosis, ebe ọ nwere mmetụta fibrinolytic. Metformin na - enyere aka wepu mkpụchi ọbara n'ime arịa ọbara.

A na-atụ aro ọgwụ ahụ na ọnụnọ nke thrombosis, ebe ọ nwere mmetụta fibrinolytic.

Mlọ ọgwụ

Mgbe a na -ewere ya ọnụ, ọgwụ ahụ na-eji nwayọ abanye na nri diges. Ntinye Metformin bụ 50%. Bioavailability anaghị agafe 60%. Nri ahụ ruru ihe kachasị na plasma n'ime awa 2-2.5.

Metformin na - ejikọ ya na albumin ọbara, mana ọ na - abanye ngwa ngwa ndu. Ọ napụrụ ya site n'ahụ ahụ akụrụ na-agbanweghi agbanwe. Oge oge ezumike bụ elekere 8-12.

Gịnị ka enyere ya?

Edere ọgwụ a maka ndị okenye na ụmụaka karịrị afọ 10 site na oke ibu na ụdị ọrịa shuga mellitus nke 2 (nke na-abụghị insulin). Enwere ike iji ọgwụ ahụ ma ụzọ abụọ yana nke abụọ (yana yana insulin).

Ihe ngosi ndi ozo maka ojiji bu:

1. Ọrịa ịba ọcha n'anya (dystrophy imeju). Ọrịa nke ntụgharị nke hepatocytes (mkpụrụ ndụ imeju) na anụ ahụ nwere mkpụrụ.
2. Polycystic ovary. Ọrịa a na - ejikarị ọgwụ insulin eme ihe. Productionmịpụta mmepụta homonụ a na ịba ụba shuga ọbara.
3. Ọrịa hyperlipidemia. Ejiri oria lipids na lipoproteins n'ime ọbara mara ọrịa ahụ.

Ngosipụta maka ojiji bụ ịba ọcha n'anya.

Ihe ngbanwe

A na-egbochi ọgwụ a na mkpụrụokwu ndị a:

• nnabata onwe onye maka metformin ma ọ bụ ndị ochie,
• ọrịa mamịrị
• mamịrị ketosis na-arịa ọrịa shuga,
• nnukwu ọrịa imeju
• ọrụ ezughi oke,
• oké afọ ọria ma ọ bụ vomiting,
• ọrịa na-efe efe siri ike
• hypoxia
• ahụ ọkụ
• sepsis
• nsogbu anaphylactic,
• infarction myocardial
• akụkụ iku ume ma ọ bụ nkụchi obi,
• a .ụrụma
• lactic acidosis,
• ụkọ calorie
• afọ ụmụaka ruo afọ 10.

Na-a drugụ ọgwụ maka ọrịa shuga

N'ikwekọ na ntuziaka ahụ, a na-enye ndị okenye nwere monotherapy ọgwụ 10001500 mg nke ọgwụ kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, a na-eji nwayọ elu kwa ụbọchị ruo 2000 mg. Oke kachasị kwa ụbọchị bụ 3000 mg nke metformin. Enwere ike ekewa ubochi ubochi abuo na ato.

Mgbe ejikọtara ya na insulin, dose nke Metformin bụ 1000-1500 mg kwa ụbọchị. N'oge usoro ọgwụgwọ, enwere ike ịchọ mmegharị insulin.

Etu esi ewere ibu ibu?

Maka ọgwụgwọ nke oke ibu, ihe kpatara ya bụ insulin na-eguzogide ọgwụ, edepụtara ọgwụ ahụ na usoro ọgwụ nke 500 mg otu ugboro. A na-abawanye ọgwụ ahụ na 2000 mg kwa ụbọchị, na-agbakwunye 500 mg kwa izu.

Metformin na-enyere aka belata ibu ma ejikọta ya na nri kwesịrị ekwesị.

Metformin na-enyere aka belata ibu ma ejikọta ya na nri kwesịrị ekwesị. Ma enweghi ike idobe ezigbo nri n'ihi ihe ize ndụ nke hypoglycemia.

Site n'akụkụ nke metabolism

Mmetụta metabolism:

• lactic acidosis,
• Nri B12 (enweghi ike igwu vitamin).

Ntụziaka pụrụ iche

Tupu arụ ọrụ na nyocha ya site na iji ọgwụ radiopaque, a na-akagbu ọgwụ. A na-ebupụ ọgwụ ọjọọ ụbọchị 2 tupu nyocha ahụ wee maliteghachi mgbe ụbọchị abụọ gachara.

Tupu ịwa ahụ, a na-akagbu ọgwụ.

Jiri n'oge ime na lactation

Ebe ọ bụ na ihe na-arụ ọrụ na-agabiga na Plasenta, a naghị atụ aro ka ụmụ nwanyị dị ime were ọgwụ a. Emebeghi ihe omimi nke oma banyere teratogenic utara nke metformin. Mgbe ụfọdụ ndị dọkịta na-enye ndị inyom dị ime ọgwụ ọgwụ a.

A na-atụ aro ị Breastụ ara n’oge a na-agwọ ya ka ọ kwụsị.

Ngwa maka ọrụ ezughi oke ọrụ

Mmekọrịta na ọgwụ ndị ọzọ

Ejiri nlezianya jiri ọgwụ a medicineụọ ọgwụ ahụ:

1. Danazole (onye na-elekọta hyperglycemic).
2. Chlorpromazine.
3. Ọgwụ.
4. Nchịkwa nke sulfonylureas.
5. Ndị NSAID.
6. Oxytetracycline.
7. Ndị na - egbochi ACE na MAO.
8. Clofibrates.
9. Ọgwụ Hormonal (gụnyere ọgwụ mgbochi).
10. Diuretics (site na otu thiazide ma ọ bụ loop diuretics).
11. Nri nkpuru nke nicotinic acid na phenothiazine.
12. Glucagon.
13. Cimetidine.

Ọ bụrụ na ngwakọta ndị dị otú ahụ dị mkpa, dọkịta ahụ na-akwadozi ị doseụ ọgwụ ahụ ma na-achịkwa ịba ụba nke shuga na lactic acid n'ime ọbara.

Mmanya ndakọrịta

Ngwaahịa a enweghị mmekorita na mmanya. Mmanya na-abawanye n'ihe ize ndụ nke hypoxia anụ ahụ, lactic acidosis na mmetụta ndị ọzọ.

Analogues ama ama nke ngwaahịa a gụnyere Glucophage (Merck Sante, France), Formmetin (Pharmstandard, Russia), Siofor (Berlin-Chemie, France). Ọgwụ ndị a nwere otu ihe arụ ọrụ - metformin hydrochloride.

Ọgwụ dịka Metformin Teva na Metformin Richter bụ mkpụrụ ndụ ihe nketa. Ha na Metformin Canon bu otu na ihe eji eme ya, ma ndi ozo mere ya.

Nyocha na Metformin Canon

Konstantin, afọ 42, St Petersburg

Anọwo m na-arụ ọrụ dị ka ọkà mmụta endocrinologist ruo ihe karịrị afọ 10. Edere ọgwụ a maka ndị ọrịa nwere ọrịa shuga na oke ibu. Ọ na - enyere aka ịhazi metabolism na ọkwa glucose ọbara. Adịghị m ahụkarị nsị na omume m.

Irina, 35 afọ, Krasnodar

Metformin bụ ezigbo ọgwụ hypoglycemic na ọgwụgwọ nke ụdị shuga 2. Ndị ọrịa m na-anabata ọgwụ ndị a nke ọma. Mgbe otu ọnwa na-a sugarụ ọbara shuga tụlee. Iji zere mgbu afọ, ana m akwado ịhapụ ị takeụ ọgwụ na afọ efu.

Po, afọ 56, Belorechensk

Amụtara m banyere ọgwụ dịka Metformin, Siofor, Glucofage sitere na endocrinologist. Ọ gwara ha ka ha lụso ọrịa shuga ọgụ. Uru Metformin ma e jiri ya tụnyere ya bụ ọgwụ ọnụ ala. Ọgwụ nyeere aka ma ọ baghị akpata nsonaazụ.

Alexander, onye gbara afọ 43, Volgograd

A na m a drugụ ọgwụ a maka mgbochi ọrịa shuga. Ọbara ọbara malitere ịba, dọkịta ahụ kwukwara ka ọ bụrụ Metformin. Ahụghị m mmetụta ọ bụla na-adịghị mma n'oge ọgwụgwọ.

Ekaterina, gbara afọ 27, Moscow

Mgbe m mụchara nwa, m bidoro gbakee ngwa ngwa. Enweghị m ike ịkwado nri siri ike ruo ogologo oge, yabụ m kpebiri ịnwale Metformin iji belata agụụ. Ọgwụ nyeere aka tufuo 5 n'arọ kwa ọnwa. Agụụ na-agụ m, enweghị m ike ị .ụbiga mmanya ókè.