Ethamsylate: ntuziaka maka ojiji, ngosipụta, dosages na analogues

Ethamsylate bụ ihe na-ahụ maka ahụ ike, nke e ji mara angioprotective na proaggregate action. Ọgwụ na -eme ka mmepe nke platelet na mpụpụ ya na ụmị ọkpụkpụ, na-eme ka ịdịmma mgbidi nke capillaries dịkwuo mma, nke mere na ha na-abanye nke nta. Ọ nwere ike ịbawanye nrapado platelet na inhibido prostaglandin biosynthesis.

Ojiji Etamsylate na-eme ka ngwa ngwa nke thrombus dịkwuo elu ma na-akwalite ntụgharị uche ya, ihe fọrọ nke nta ka ọ ghara imetụta ọdịnaya fibrinogen n'ọbara na oge prothrombin. O nweghi ihe hypercoagulant; iji ya ọgwụgwọ ogwu anaghị emetuta otiti nke ọbara.

Site na nchịkwa intravenous (iv), ịgbalite usoro hemostasis na - apụta n'ime oge 5-15 mgbe ịgba ntụtụ ahụ, a na - enweta mmetụta kachasị mgbe awa 1-2 gachara.

Mgbe etinyere mbadamba Ethamsylate, edere nsonaazụ kachasị mgbe awa 2-4 gachara. Ntinye dị irè nke ihe na-arụ ọrụ n'ime ọbara bụ 0.05-0.02 mg / ml. Ọgwụ ahụ na-apụta na mmamịrị (80%), na obere ego na bile.

Mgbe usoro ọgwụgwọ gachara, usoro ọgwụgwọ ahụ dịruru ụbọchị 5-8, jiri nwayọ daa. Nnukwu arụmọrụ yana ọnụ ọgụgụ dị nta nke contraindications nke ọgwụ na-enye nyocha dị mma banyere Etamsilate site n'aka ndị dọkịta.

Edeghị ọgwụ a maka oke porphyria, thrombosis na ịtụrụ ime.

Usoro onunu ogwu:

Ethamsylate dị ka ihe ngwọta maka ntụtụ ọgụ na intramuscular, na mbadamba na mbadamba maka ụmụaka.

Ihe ngosi Ethamsilate

Dabere na ntuziaka maka ojiji nke Etamsylate, a na-eji ọgwụ ahụ eme ihe maka monotherapy yana na usoro ọgwụgwọ dị mgbagwoju anya maka:

Ppingkwụsị na igbochi ọbara ọgbụgba na-egbochi isi mmalite nke ọrịa mamịrị,
Ihe ogwugwo na omume otolaryngological (tonsillectomy, microsurgery ear na ndi ozo),
Phtwa ahụ akpụ akpụ (mwepu cataract, keratoplasty, ịwa ahụ antiglaucomatous),
Arụ ọrụ eze (mwepụ nke granulomas, cysts, nhichapụ ezé),
Arụmọrụ uro (prostatectomy),
Ndị ọzọ, gụnyere akụkụ ara, gụnyere - akụkụ ahụ na anụ ahụ nwere netwọ mgbasa sara mbara,
Nleta anya mberede maka akpịrị na ọnya afọ,
Hemorrhagic diathesis.

Ntuziaka maka iji Etamsylate - mbadamba na injections

A na-eduzi injections ethamsilate intravenously na intramuscularly, na omume ophthalmic - n'ụdị nke anya na azụ na retrobulbar.

Usoro onunu ogwu maka ndi okenye:

N'ime, otu ọgwụ Ethamsilate maka ndị okenye bụ 0.25-0.5 g, dị ka ihe na-egosi, enwere ike ịbawanye ọgwụ ahụ ruo 0.75 g, parenterally - 0.125-0.25 g, ma ọ bụrụ na ọ dị mkpa ruo 0.375 g.

Ihe ogwugwo - maka mgbochi nke etamsylate, a na-abanye ha n’ime / n’ime ma obu n’ime m elekere 1 tupu emee ya n’uzo nke 1-2 ml (1-2 ampoules) ma obu n’ime mbadamba mbido 2-3 (0.25 g) awa ato tupu ahuru ya. .
Ọ bụrụ na ọ dị mkpa, gbanye ọgwụ mgbochi 2-4 ml n'ime oge ịwa ahụ.

Mgbe enwere ọghọm ọbara ọgbụgba, a na-enye 4 to 6 ml (2-4 ampoules) kwa ụbọchị ma ọ bụ mbadamba 6,8 Etamsylate kwa ụbọchị. Usoro a na-ekesa usoro ahụ ruo awa iri abụọ na anọ.

Ihe mberede: ngbanye ozugbo na / n’ime ma obu intramuscularly, emesia kwa awa ano n’ime 4-6 n’ime / n’ime, n’ime / m ma obu n’ime. A na-atụ aro ịgba ọgwụ mgbochi.

Na ọgwụgwọ metro- na menorrhagia, ntuziaka maka iji ethamzilate maka oge nsọ na-atụ aro ị doụ ọgwụ 0 g g ma ọ bụ 0.25 g parenterally (na-agagide nri) mgbe awa 6 maka ụbọchị 5-10.

Mgbe ebumnuche mgbochi - 0,25 g nke ọnụ ugboro anọ kwa ụbọchị ma ọ bụ 0,25 g parenterally ugboro abụọ kwa ụbọchị n'oge ọbara ọgbụgba (ọbara ọgbụgba) na abụọ n'ime usoro ole na ole gara aga.

Na myacroangiopathy na-arịa ọrịa shuga, a na-agbanye injections Ethamsylate na mmanụ maka ụbọchị 10-14 na otu usoro 0.25-0.5 g ugboro atọ n'ụbọchị ma ọ bụ na ọmụmụ nke ọnwa 2-3 na ị doụ ọgwụ mbadamba 1-2 ugboro atọ kwa ụbọchị.

Site na diathesis hemorrhagic, usoro ọgwụgwọ na-enye maka iwebata ọgwụ ahụ n'ihe ọmụmụ 1.5 g kwa ụbọchị na oge niile maka ụbọchị 5-14. N'okwu ndị siri ike, ọgwụgwọ na-amalite site na nchịkwa parenteral nke 0.25-0.5 g 1-2 ugboro n'ụbọchị maka ụbọchị 3-8, wee dezie ya site n'ọnụ.

N'ime ọgwụgwọ ịgwọ ọrịa uterine ọbara na-adịghị mma, a ga-eburịrị Ethamsylate ọnụ na 0.6 grams kwa awa isii. Oge ọgwụgwọ ji ihe dịka ụbọchị iri. Mgbe ahụ, a na-enye usoro ịkwụ ụgwọ nke 0.25 g ugboro anọ kwa ụbọchị ozugbo na-agba ọbara (usoro 2 ikpeazụ). A na-elekọta Parenteral 0.25 g ugboro abụọ n'ụbọchị.

Na ophthalmology, a na-achịkwa ọgwụ subconjunctival ma ọ bụ retrobulbar - na usoro nke 0.125 g (1 ml nke ihe ngwọta 12.5%).

Maka umuaka:

N'oge arụmọrụ prophylactically, site n'ọnụ na onunu ogwu nke 10-12 mg / n'arọ na abụọ doses maka ụbọchị 3-5.

Ihe mberede mgbe ị na - arụ ọrụ - ethamzilate injection intravenously 8-10 mg / kg body body.

Emechara ịwa ahụ, maka mgbochi nke ọbara ọgbụgba - n'ime, na 8 mg / kg.

Site na ọrịa hemorrhagic n'ime ụmụaka, etinyere Ethamsylate n'ime otu ọgwụ nke mgmgg mg / kg 6, ugboro atọ n'ụbọchị. Ogologo ọgwụgwọ ya bụ ụbọchị 5-14, ọ bụrụ na ọ dị mkpa, a na-emeghachi ya ugboro ugboro ka ụbọchị asaa gachara.

A na-eji ọgwụ ahụ eme ihe n’ime ụmụaka karịrị afọ 6. Ejila ọnụnọ nke hemoblastoses.

Veterinarian:

A na-ejikwa Ethamsylate na omume ọgwụgwọ ọrịa anụmanụ. Usoro ọgwụgwọ maka nwamba bụ 0.1 ml kwa n'arọ nke ibu anụmanụ, ugboro 2 n'ụbọchị (injections).

Contraindications Etamsylate

A na-ejikọ ihe mgbochi nke ọgwụ ahụ na thrombosis mụbara na ọnọdụ metụtara:

Ọgwụ nzuzo nke ọgwụ ahụ,
Thrombosis, thromboembolism, ịba ụba ọbara ọbara,
Formdị nnukwu porphyria,
Hemoblastosis (lymphatic na myeloid leukemia, osteosarcoma) n'ime ụmụaka.

Kpachara anya banyere ọbara ọgbụgba na nkwụghachi nke anticoagulants.

Na ọgwụ ọgwụ ekwekọghị ọgwụ ndị ọzọ. Ejikọkwala ntụtụ ahụ na ọgwụ na ihe ndị ọzọ.

Mmetụta Sideam Etamzilat

mmetụta nke ahụ erughị ala ma ọ bụ ọkụ n'ime mpaghara obi,
mmetụta nke ịdị arọ n’olulu afọ
isi ọwụwa na ọnya afọ,
branching nke network vaskụla na ihu
mbelata n'ọbara ọbara systolic,
mmetụta ị na-enwe n'ahụ necrosis nke anụ ahụ (ọnụọgụ), nguzobe nke "ọgazị ezumike" ma ọ bụ ihe na-ekwekọghị n'okike, mmetụ ahụ.

Analogs nke Etamsilat, ndepụta

Mgbe ị na-achọ onye nnọchi, biko mara na naanị analogue nke Etamsilate edere bụ Dicinon. Lozọ ndị ọzọ na-esi emetụta ahụ:

Ekwesịrị ịnwe dọkịta ọ bụla dochie Etamzilat na analogues! Ọ dị mkpa ịghọta na nkuzi a maka iji mbadamba Etamsylate na injections emetụtaghị analogues na ekwesighi iji ya dịka nduzi maka ịme ihe na-enweghị nhọpụta na ndụmọdụ nke dọkịta.

Ọnọdụ nchekwa
Chekwaa n’ebe di omimi n’ebe umuaka no n ’onodu okpomoku kariri 25 Celsius.

Omume ọgwụ

Hemostatic, angioprotective n'ụlọnga.

Ọ na-eme na njikọ platelet nke hemostasis. Ọ na - akpali mwepụta nke platelet na ntọhapụ nke platelet site na ụmị ọkpụkpụ, na-eme ka ọnụ ọgụgụ ha na arụ ọrụ physioloji. Ọ na - eme ka ọnụọgụ thrombus bụrụ nke dị elu, nke nwere ike ịbụ n'ihi mkpalite nke sel thromboplastin anụ ahụ, ma na - eme ka nkwụghachi azụ nke thrombus. Ọ nwere ọrụ antihyaluronidase, na-egbochi nkewa mucopolysaccharides nke vaskụla olu ahụ ma mee ka acid kwụsie ike, n'ihi nke nguzogide nke capillaries na-abawanye, ngwangwa na isi nke microvessels na-ebelata. Ọ nweghị mmetụta hypercoagulant, ọ naghị emetụta ọkwa nke fibrinogen na oge prothrombin.

Mmetụta kachasị mgbe ejiri ya bụ nke ekwuru na mgbe awa 3 gasịrị. Na onodu ogwu nke 1-10 mg / n'arọ, ogo nke ihe bu ihe kwesiri ekwesi na onodu ogwu a, mmụbawanye nke onwonye na-eduga naanị mmụba dị mma na arụmọrụ. Mgbe usoro ọgwụgwọ gasịrị, nsonaazụ ahụ na-adịgide ruo ụbọchị 5-8, jiri nwayọ daa.

Mlọ ọgwụ

Mgbe nchịkwa ọnụ gasịrị, ọ na-ezucha oke kpamkpam site na eriri afọ. A na-enweta mgbanye ọbara kachasị n'ọbara mgbe awa 3-4. Ntinye ọgwụgwọ dị mma n'ọbara bụ 0.05-0.02 mg / ml. Ọ na - ejikọ ya ike na protein na sel sel. A na-ekesa ya n’esepụ aka na anụ ahụ dị iche iche (ọ dabere n’onodu ọbara ha si enweta ya). Ihe dị ka 72% nke nchịkwa a na-adịpụrụ anya n'ime awa iri abụọ na anọ mbụ nwere mmamịrị na steeti na-agbanweghi. Ethamsylate na-agafe ihe mgbochi placental ma banye n’ime mmiri ara.

Ihe ngosi maka ojiji

Mgbochi na ịchịkwa ọbara ọgbụgba n'ime oke anụ ahụ na nke ime dị iche iche nke etiologies dị iche iche, ọkachasị ma ọ bụrụ na ọ bụ mmebi endothelial kpatara:

- mgbochi na ọgwụgwọ nke ọbara ọgbụgba n'oge ịwa ahụ na otolaryngology, gynecology, obstetrics, urology, dentistry, ophthalmology and plastic surgery,

- mgbochi na ọgwụgwọ nke ọbara ọgbụgba ọbara nke etiologies na mpaghara dịgasị iche iche: hematuria, metrorrhagia, hypermenorrhea bụ isi, hypermenorrhea na ụmụ nwanyị nwere mgbochi afọ intrauterine, imi imi, ọbara ọgbụgba.

Usoro onunu ogwu na nhazi

Itinye n'ime n'ime n'agbanyeghị nri nri.

N'ime oge ịwa ahụ, a na-enye ndị okenye 0,5-0.75 g (mbadamba 2-3) awa 3 tupu awa ịwa ahụ, a na-enye ụmụaka gafere afọ 12 na ọnụego nke 1-12 mg / kg body (1 / 2-2 mbadamba) kwa ụbọchị na 1-2 doses, n'ime ụbọchị 3-5 tupu ịwa ahụ.

Ọ bụrụ na ọghọm dị n'ọbara nke ọbara ọgbụgba, a na-enye ndị okenye 1-2 g (mbadamba 4-8) ọgwụ, overmụaka karịrị afọ iri na abụọ ka etinyere mkpụrụ ndụ 8 mg / n'arọ (mbadamba 1-2) n'otu ụbọchị (na usoro onunu ogwu) n'ime ụbọchị mbụ mgbe ọ gasịrị. arụmọrụ.

N'ihe banyere ọbara diachesis (thrombocytopathy, ọrịa Villeurbrand, ọrịa Wörlhoff), a na-enye ndị okenye iwu 1.5 g ihe ọmụmụ (mbadamba 6), ụmụaka gafere afọ iri na abụọ ka afọ na-enye ọgwụ mg / mg ibu n'arọ kwa ụbọchị n'ime oge atọ kewara atọ. oge maka 5-14 ụbọchị. Usoro ọgwụgwọ, ọ bụrụ na ọ dị mkpa, enwere ike imeghari ya mgbe ụbọchị asaa gachara.

Na microangiopathies na-arịa ọrịa shuga (retinopathies nke nwere ọbara ọgbụgba), a na-enye ndị okenye usoro ọmụmụ 0.25-0.5 g (mbadamba 1-2) ugboro atọ n'ụbọchị maka ọnwa 2-3, ụmụaka karịrị afọ 12 - 0.25 g (1 mbadamba 1 ) 3 ugboro n'ụbọchị maka ọnwa 2-3.

N'ime usoro ọgwụgwọ nke metro na menorrhagia, 0.75-1 g (mbadamba 3-4) ka edepụtara maka ya kwa ụbọchị n'ime usoro 2-3, na-amalite site na ụbọchị nke ise nke nsọ ahụ a tụrụ anya ya ruo ụbọchị nke ise nke nsọ nwanyị na-esote. Onweghi ihe akaebe banyere mkpa ọ dị idozi usoro usoro onunu ogwu ka ndi mmadu nwere nsogbu imeju na akụrụ.