Nkọwa na ntuziaka maka iji ọgwụ Berlition

Ntinye akwụkwọ dị n'ụdị usoro ị followingụ ọgwụ:

• Na-etinye uche maka ihe ngwọta maka infusion: akwụkwọ ndụ akwụkwọ ndụ na-acha odo odo, na-ahụ ụzọ (Berlition 300: 12 ml na ampoules iko gbara ọchịchịrị, 5, 10 ma ọ bụ 20 ampoules na kaadiboodu, 1 tree n'ime mkpọ kaadiboodu, Berlition 600: 24 ml na iko ampoules gbara ọchịchịrị, ampoules 5 na paịlị rọba, 1 pallet na ngwugwu)
• Mbadamba ihe eji etinye ihe nkiri: gburugburu, biconvex, n'otu akụkụ - ihe ọghọm, acha odo odo na-acha odo odo, n'akụkụ nkebi a na - ahụkarị akụkụ mkpụrụ (pcs iri na abụọ. Na blisters, 3,6.10 blisters na kaadiboodu).

Isi ihe na - arụ ọrụ bụ thioctic acid:

• Na 1 ampoule nke uche - 300 mg ma ọ bụ 600 mg,
• Na mbadamba 1 - 300 mg.

Mlọ ọgwụ

Acid Thioctic (alfa lipoic) bụ antioxidant endogenous nke usoro (na - enweghị ihe ọ bụla) na ime ya. Ọ bụ nke otu coenzymes etinye aka na decarboxylation nke alpha-keto acid. Ngwakọta a na - enyere aka belata glucose plasma ma mee ka ịbawanye ụba glycogen, belata insulin na - eguzogide ọgwụ, na - ekere òkè na nhazi nke metabolism metabolism, na - emekwa ka metabolism dị ala.

Ebe ọ bụ na thioctic acid nwere ihe antioxidant, ọ na-echebe mkpụrụ ndụ na mbibi site na ngwaahịa ha na-emebi, na-egbochi mmepụta nke ngwaahịa na-aga n'ihu nke glycosylation nke protein na mkpụrụ ndụ akwara, nke a na-esonyere ọrịa shuga, na-eme ka ọbara na -akwụsị ma ọ bụ microcirculation, ma na-abawanye mkpanaka ahụ nke antioxidant glutathione. N’inye mbelata ọbara glucose na plasma ọbara, ihe mejupụtara Berlition na-emetụta ihe ọzọ glucose metabolism na ọrịa shuga mellitus, na-ebelata mkpokọta metabolites n'ụdị polyols na, n'ihi nke a, na-ebelata edema nke anụ ahụ.

Thioctic acid na-ekere òkè na metabolism nke abụba, nke na-eduga na mmụba na biosynthesis nke phospholipids, akpan akpan phosphoinositides, na-ebute normalization nke mebiri emebi membranes cell. Ọzọkwa, akụrụngwa ahụ na-eme ka ihe ndị na-emebi akwara dị ike na metabolism, na-enye gị ohere wepu nsị na-egbu egbu metabolites (pyruvic acid, acetaldehyde). Thioctic acid na - egbochi ịmepụta nke oke ikuku nke oxygen oxygen, na - ewepụ ischemia na endoneural hypoxia, na - ebelata akara nke polyneuropathy, gosipụtara na mmetụta nke ọnya, ihe mgbu ma ọ bụ na - agba ọkụ na aka, yana paresthesias. Ya mere, ihe a na - eme ka metabolism dị ọcha ma na - eme ka ihe na - emetụta ya. Ojiji nke thioctic acid n'ụdị nnu nke etinne etinyere na-eduga na mbelata ogo ogo mmetụta ndị ọzọ ọ na-enwe.

Mlọ ọgwụ

Site na nchịkwa intravenous nke Berlition, ntinye uche kachasị nke ihe na-arụ ọrụ na plasma ọbara bụ ihe dịka 20 μg / ml 30 nkeji mgbe mmụba ahụ, na mpaghara dị n'okpuru oge ịta ahụ bụ ihe dịka 5 μg / h / ml. Thioctic acid nwere “mbu ụzọ” sitere na imeju. A na - eme ihe metabolites ya n'ihi conjugation na oxidation nke yinye akụkụ. Olu nke nkesa dị ihe dịka 450 ml / n'arọ. Mkpochapụ plasma bụ 10-15 ml / min / n'arọ. A na - ekepụta Thioctic acid site na akụrụ (80-90%), ọkachasị n'ụdị metabolites. Ọkara ọkara bụ ihe dịka nkeji iri abụọ na ise.

Ntuziaka maka ojiji nke Berlition: usoro na usoro onunu ogwu

A na-a drugụ ọgwụ ahụ otu ugboro n'ụbọchị, n'ụtụtụ, ọkara awa tupu nri ụtụtụ. Mbadamba mbadamba osisi agaghị ata ata ma gwepịa. Ọgwụ kwa ụbọchị maka ndị okenye bụ 600 mg (2 mbadamba).

Ọgwụ dị n'ụdị itinye uche, wee jiri 0.9% sodium chloride solution, gwọọ ya na 250 ml maka ọkara otu elekere. Ọgwụ kwa ụbọchị maka ndị ọrịa toro eto bụ 300-600 mg. Mmeghe nke Berlition intravenously na-abụkarị izu 2-4, mgbe nke a gasịrị, a na-ebugharị onye ọrịa ahụ ọgwụ.

Ntụziaka pụrụ iche

N'oge ị na-agwọ ọrịa, ị kwesịrị ịhapụ ị drinksụ ihe ọ -ụ -ụ mmanya nwere mmanya, ebe ethanol na-ebelata ịdị irè nke thioctic acid.

Ndị ọrịa nwere ọrịa shuga kwesịrị ilebara ọkwa glucose ọbara ha anya.

Rie ngwaahịa mmiri ara ehi, were magnesium na nhazi ígwè n’oge ọgwụgwọ kwesịrị n’ehihie.

Site na njikwa nkwonkwo ọgwụ na ndị na-ahụ maka ọnya hypoglycemic na insulin, a na-eme ka mmetụta nke ikpeazụ ahụ ka mma.

Mmetụta ikike ịkwọ ụgbọala na usoro dị mgbagwoju anya

Ọmụmụ ihe banyere nsonazụ Berlition na ọsọ nke ihe mmeghachi omume psychomotor na ikike ịghọta na ngwa ngwa ịtụle ọnọdụ ndị a na-adịghị ahụkebeghị, yabụ, n'oge ọgwụgwọ ọgwụ ahụ, ekwesịrị ilebara anya pụrụ iche mgbe ị na-anya ụgbọ ala ma na-arụ ụdị ọrụ dị ize ndụ nke chọrọ mmụba nke itinye uche na itinye uche.

Mkparịta ụka ọgwụ ọjọọ

Ebe ọ bụ na usoro nke cheotics nke thioctic acid na ọla nwere ike ikwe omume, ekwesighi ịkọ ya na nhazi ígwè. Nchikota nke ogwu na cisplatin belata ike nke ndi azu.

Thioctic acid na - agwakọta na ụmụ irighiri shuga, na - akpụkọta ogige ndị mejupụtara ihe fọrọ nke nta ka ọ ghara ịgbari. A machibidoro iji mmiri mee ihe megidere ndabere nke ọgwụgwọ ya na ngwọta Ringer, dextrose, fructose na glucose, yana ngwọta ndị na-agabiga na mbibi na SH-otu. Ọgwụ ahụ na-akwalite mmetụta hypoglycemic nke insulin na ọgwụ hypoglycemic ndị ọzọ na-eji n'otu oge. Etaniol dichasịrị ike ọgwụgwọ nke Berlition.

Nkịtị analogues nke Berlition bụ Espa-Lipon, Oktolipen, Thiogamma, Lipothioxon, Thiolipon na Neuroleipone.

Nyocha nke Berlition

Dabere na nyocha, a na-ejikarị Berlition 300 na Berlition 600 n'ụdị usoro ọgwụgwọ (mbadamba nkume, ntụtụ) iji gwọọ ndị ọrịa nwere ọrịa mellitus na ọrịa imeju. Ọzọkwa, a na-ewere ọgwụ dị ka nke ọma ọ bụghị naanị n'etiti ndị ọrịa, kamakwa na gburugburu ọgwụ. N'ime 95% nke usoro, ọgwụgwọ na Berlition na-enye nsonaazụ dị mma, yana mmetụta ndị na-adịghị mma na-anọghị nso. Mana ekwesịrị iburu n'uche na ọ bụ naanị ọkachamara kwesịrị ịkọwa ọgwụ wee mepụta usoro ọgwụgwọ.

Ihe ngbanwe

Dịka ntuziaka ahụ si dị, Berlition na contraindicated na:

• Onweghi nnabata nke alfa lipoic acid ma obu ihe inyeaka nke ogwu a
• N’agbata afọ 18
• Ime na inye ara,

Mkpokọ mkpụrụ osisi 300 a na-enye ọgwụ mgbochi maka ọgwụgwọ nke ndị ọrịa na-arịa malabsorption nke glucose-galactose, enweghị lactase na galactosemia. Achọpụtaghị ahihia capsules maka ndị ọrịa nwere mkpụrụ osisi fructose.

N'iji mmiri Berlition, akpachara anya kwesịrị ịdị na-arịa ọrịa shuga. Ọ bụrụ na ọ dị mkpa iji ọgwụ maka ụdị ndị ọrịa a, a ga-enyocha glycemia mgbe niile.

Usoro onunu ogwu na nhazi

Edere ahihia na mbadamba ihe na capsules n'ime. Achọghị ọgwụ a ka ọ ghaa ma ọ bụ ghee mmiri n'oge eji ya. A na-ewere kwa ụbọchị otu ugboro kwa ụbọchị, ihe dị ka ọkara otu awa tupu nri ụtụtụ. Iji nweta oke ọgwụgwọ kachasị, a na-atụ aro ịgbasochi iwu nnabata anya akọwapụtara na ntuziaka maka Berlition.

Dịka iwu, oge ọgwụgwọ na Berlition dị ogologo. Ọ bụ dibia bekee na-ekpebi oge ọ ga-anabata gị. Usoro onunu ogwu:

• Na polyneuropathy na-arịa ọrịa shuga - 600 mg kwa ụbọchị,
• Site na ọrịa imeju - 600-1200 mg nke thioctic acid kwa ụbọchị.

N'okwu ndị siri ike, a na-atụ aro ịkọ ọgwụ Berlition onye ọrịa n'ụdị ihe ngwọta maka infusion.

A na-eji akwụkwọ mmachi maka nkwadebe nke ihe ngwọta maka infusion mee maka nchịkwa intravenous. Dịka ihe mgbaze, naanị 0.9% sodium chloride kwesịrị iji, 250 ml nke edozi edozi edozi maka ọkara otu elekere. Usoro onunu ogwu:

• Na ụdị polyneuropathy na-arịa ọrịa mamịrị - 300-600 mg nke Berlition,
• N'ime ọrịa ọrịa imeju siri ike - 600-1200 mg nke thioctic acid kwa ụbọchị.

A na-eche ụdị Parenteral nke ọgwụ ahụ maka ọgwụgwọ, oge nke ya bụ 0-1-1 ọnwa, mgbe nke a gasịrị, dịka iwu, a na-ebugharị onye ọrịa ahụ na mbadamba ma ọ bụ capsules Berlition.

Nsonaazụ

Ihe Berlition nwere ike ibute nsogbu ndi a:

• Usoro nri: ọgbụgbọ na ọgbụgbọ, afọ ntachi ma ọ bụ afọ ọsịsa, mgbanwe nke uto, ọnyụnyụ ọbara.
• Ọkpụkpụ akwara na akụkụ ụjọ: mgbe a gbasịrị ọsọ ọsọ na akwara, ọdịdọ, mmetụta nke oke isi, diplopia,
• Ọkpụkpụ obi: hyperemia nke ihu na elu ahụ, tachycardia, mmetụta nke ike na mgbu n'ime obi,
• Ihe nfụkasị ahụ: ọnya anụ ahụ, itching, eczema, urticaria.

Mgbe ụfọdụ, mgbe a na - enweta ọgwụ mgbochi ọbara n'ime ọgwụ dị elu, oke anaphylactic ujo nwere ike ịmalite. Ọzọkwa, mmepe nke isi ọwụwa, nkụda mmụọ, imerụ anya anya, mkpụmkpụ ume, purpura na thrombocytopenia agaghị achịcha.

N'ime ndị ọrịa nwere polyneuropathy na ọkwa mbụ nke ọgwụgwọ na Berlition, mmụba nke paresthesia ga-ekwe omume, ya na mmetụta nke "ọgazị bumps".

Usoro na ọnọdụ nchekwa

Dịka ntuziaka ahụ si dị, ekwesịrị ịchekwa mmiri n'ụlọ ebe kpọrọ nkụ, ọchịchịrị ma dị jụụ.

Uche maka nza maka infusion nwere ndụ nchekwa nke afọ 3. N’ụdị agachara, a gaghị echekwa ihe ngwọta maka infusion ihe karịrị awa 6 (ọ bụrụ na a na-echebe karama ahụ n’anyanwụ).

Mpempe akwụkwọ 300 Mbara mbadamba mkpụrụ ndụ nwere ndụ nchekwa afọ 2, Berlition 300 capsules - afọ 3, Berlition 600 - 2.5 afọ.

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