Tsifran ": ntuziaka maka ojiji, ihe na-egosi na contraindications

Cifran bụ ọgwụ nje nke otu nnukwu ụlọ ọrụ na-emepụta ọgwụ na India, Ranbaxy Laboratories Ltd.

Ngwakọta ọrụ nke Cifran bụ ciprofloxacin hydrochloride (nke ruru 500 mg ciprofloxacin), nke a na-eji agwọ ọrịa nje.

Ihe ogwu ogwu:

Ciprofloxacin bụ otu ọgwụ ọgwụ akpọ quinolones / fluoroquinolones. Ha na-egbochi ntụrụndụ nke DNA ma na-egbochi ihe ndị dị ndụ na DNA, na-eme ka "mbibi" nke DNA nwere ọnye abụọ. Metabolized na imeju, ọkara ndụ: (n'ime ụmụaka), (n'ime ndị okenye). Mgbapu: mmamiri aru

Ihe ngosi maka iji ndi okenye:

ọrịa ọla kọpa
Ọrịa ENT
eze mgbu na mmiri na-egbu (topically),
ịba na ịba na-akpata ịba ọcha n'anya,
ọgbụgba
ọrịa anya
ụkwara nta
nje nke ọrịa Escherichia coli, Campylobacter Euni ma ọ bụ ụdị Shigella dị iche iche mere.
ọrịa akụrụ
ọrịa prostatitis,
sepsis
Ọrịa nkwonkwo na ọkpụkpụ nke enterobacter cloaca, serration nke marcescens ma ọ bụ Pseudomonas aeruginosa,
anụ ahụ dị nro na nhazi anụ ahụ,
anthrax.

Ihe ngosi maka iji "Tsifran" maka umuaka:

Ọgwụgwọ na mgbochi nke anthrax.
Nsogbu Pseudomonas aeruginosa mere site n'aka ụmụaka site na afọ ise ruo afọ iri na asaa na-arịa ọrịa mkpụrụobi (cystic fibrosis) nke ngụgụ.

Tsdị "Tsifran" dị n'ụdị mbadamba ihe mkpuchi-fim n'ime usoro nke 250 mg na 500 mg, n'ụdị nke anya anya yana n'ụdị nke itinye ihe.

"Tsifran": Ntụziaka maka ime n'oge afọ ime na lactation

Imirikiti ọmụmụ achọpụtagoghị ihe egwu dị njọ na arụrụ arụ nke nne mgbe ụmụ nwanyị were ciprofloxacin ma ọ bụ ọgwụ mgbochi quinolone / fluoroquinolone n'oge ọnwa atọ mbụ nke ịtụrụ ime. Ebe ọ bụ na ọmụmụ ihe ndị a gụnyere tumadi ụmụ nwanyị na-ewere ciprofloxacin, ọ bụ naanị ihe ndị na-esite na iji Cifran ruo ogologo oge amaghị. Agbanyeghị, enweghi ọghọm dị n'ihe ọmụmụ nwa na obere ụmụaka amụrụ ogologo oge nke iji nri nri emeprofloxacin.

Naanị ọkachamara n'ọrịa ụmụ nwanyị na-ahụ nwanyị ahụ n'oge ime na lact nwere ike ikpebi ma uru Cyfran nwere maka nne na-enwe ihe egwu dị na ogwu nke nwa ebu n’afọ.

Enwere ike jikọtara ọtụtụ mmetụta ndị metụtara ojiji Cyfran. Ndị kachasị ewu ewu gụnyere:

ọgbụgbọ
isi ọwụwa
ihe nwu
acha ọbara ọbara na anụ ahụ (ọkachasị mgbe ekpughere ya). Ọ dị mma iji anwụ na-acha anwụ anwụ mgbe ị na-apụ n’azụ mgbe ị gachara "Tsifran"
ọla uto n'ọnụ
vomiting
mgbu afọ
afọ ọsịsa

Nsonaazụ ndị ọzọ dị njọ (adịkarịghị, mana ewezugaghị ya):

Mmepo.
Ike gwụrụ.
Ọcha akpụkpọ ahụ siri ike.
Mbibi nke imeju, nke gosipụtara site na mgbaàmà ndị a: jaundice (edo edo na anya), mmamịrị gbara ọchịchịrị, ọgbụgbọ, ọgbụgbọ, agụụ na-egbu, mgbu na afọ aka nri.
Tendon edema, ọkachasị n’ebe ụmụ nwanyị nọ karịrị afọ 60. Edema, n'aka nke ya, na - amụba ike nke nkụpu akaị na oge anụ ahụ. Tendon edema nwere ike ime ọtụtụ ọnwa mgbe akwụsịrị iji Cyfran.
Ọ bụ ezie na ejiri Cifran na-agwọ ọrịa nke ọnụ ọgụgụ ọbara ọcha dị ala, ọ nwere ike iji aka ya belata ọnụ ọgụgụ mkpụrụ ndụ ọbara ọcha na ahụ. Nke a na - ebute nsogbu nke sistem, ọ na - emekwa ka mmadụ nwekwuo ike ibute ọrịa.
Enslọ ọrụ ọnụnọ (na-enwetakarị uche nwute ọkụ anyanwụ).
Ihe mgbawa na-akawanye njọ n’ebe ndị ọrịa nwere ọrịa uche. Nke a nwere ike ime ka mmadụ chee echiche igbu onwe ya.

Contraindications:

Allergy na ciprofloxacin.
Myasthenia gravis (ọrịa autoimmune nke neuromuscular system).
Akwụkwụ na-adọ
Ọrịa obi.
Akụrụ ma ọ bụ ọrịa imeju.

Agaghị etinye ya na ọgwụ ndị a:

"Tizanidine" - a na - emeso spasticity muscle. Egwu: ihe ọghọm nke nsonaazụ etinyere na nkọwa nke “Tsifran” (ntuziaka maka ojiji) na-abawanye.
"Warfarin" bụ ọgwụ eji agwọ ọgwụgwọ ọrịa ọgbụgba. Egwu: ịba ụba nke ọbara ọgbụgba.
"Theophylline" - na - emepere ikuku ụzọ na ọgwụgwọ ọgwụgwọ ashma. Egwu: n'otu oge iji "Theophylline" na "Tsifran" nwere ike ibute ime mmụọ, yana imebi ụda obi.
Sildenafil ("Viagra") bụ ọgwụ eji eme ihe na ọgwụgwọ nke erectile dysfunction. Egwu: ịbawanye sildenafil n'ime ọbara, enwere ike ịdaba na nsonaazụ nke Viagra.
"Pentoxifylline-Teva" - eji meziwanye mgbasa mpaghara. Egwu: ogo ọgwụ a n’ọbara na-ebili ma nwekwa ihe ọghọm nsonaazụ ọ na-abawanye.
"Omeprazole" bụ ọgwụ eji egbu Helicobacter pylori ma gwọọ ọrịa gastroesophageal reflux. Egwu: ọkwa "Tsifran" n'ime ọbara na-ebelata, si otú a na-eme ka ịdị irè nke ọgwụ a dịkwuo njọ.
Calcium, magnesium ma ọ bụ ihe eji eme ka ígwè (gụnyere n'ụdị mbadamba nke effervescent). Egwu: ịdị irè nke Tsifran na-ebelata.
Antacids bụ ọgwụ ndị na-egbochi acid n'ime afọ. Iyi egwu: arụmọrụ “Tsifran.
Mbadamba nke cifran nwere ike ime ka mmetụta caffeine dịkwuo elu.

Ndị ọrịa a na-awa ahụ (gụnyere ịwa ahụ eze) kwesịrị ịdọ ndị dọkịta na-awa ahụ ma ọ bụ ọgwụ na-agwọ ọrịa aka banyere ị aboutụ Cifran. Ngwọta a nwere ike imetụta ọgwụ ndị ọzọ eji eme ihe n’oge ịwa ahụ.

N'agbanyeghị eziokwu ahụ bụ na a na-ejikarị ọgwụ ahụ maka ụfọdụ ọrịa nje, ọ naghị arụ ọrụ mgbe niile, yabụ na ọ dị mkpa ka dọkịta depụta ule iji chọpụta ndụmọdụ nke ịdebe Cyfran. Ntụziaka maka iji ya abụghị naanị ngosipụta dịgasị iche iche, kamakwa ọtụtụ mgbochi afọ, yabụ anaghị etinye onwe gị ọgwụ.

Otu esi ewere "Tsifran" na ọrịa prostatitis na ọrịa ndị ọzọ

Ọ bụ ihe nwute, ọ nwere obere ọrụ megide nje anaerobic (chlamydia na mycoplasma), nke na-enye ohere ka ndị ọrịa guzobe onwe ha na prostate, na usoro ọmụmụ ugboro ugboro nke Cyphran na-atụghị anya ọdịda na oge ọgwụgwọ bara uru.

Maka ndị okenye nwere mgbaàmà mbụ nke ọrịa prostatitis, a na-enyekarị mbadamba nkume Cifran na usoro nke 500 mg ugboro abụọ n'ụbọchị abụọ ruo izu anọ. Agbanyeghị, usoro ntuziaka maka ị ga-eburu “Tsifran” nye onye ọrịa ahụ site n'aka onye ọrịa urologist, dabere n'ịdị ogo ọrịa ahụ.

Otu nnyocha na South Korea gosiri na njikọta galiki na ciprofloxacin dị elu na ciprofloxacin naanị maka ịgwọ ọrịa prostatitis na-adịghị ala ala. Ndị ọrụ nyochara ọgwụ antimicrobial na mgbochi mkpị nke galiki, yana mmetụta nke galiki, yana ciprofloxacin na oke oke nwoke nwere ọrịa prostatitis na-adịghị ala ala.

Ngụkọta iri anọ na anọ nwere ọrịa a ka ekenyebere ndị otu ọgwụgwọ anọ na-enweghị mmerụ ahụ: njikwa, galọn, nke na-enweta naanị ciprofloxacin, na enweta galik gbakwunyere na ciprofloxacin. Mgbe ọgwụgwọ izu atọ gachara, oke ndị ahụ na ndị otu galiki nwere mbelata nke ukwuu na uto nje na enwere ọganihu na mgbaàmà nke mbufụt prostate ma e jiri ya tụnyere ndị na-ahụ maka njikwa. Agbanyeghị, n'ime otu e nyere galik gbakwunyere ciprofloxacin, enwere mbelata nke ukwuu na uto nje na mmụba dị ukwuu na mgbaàmà nke mbufụt prostate ma e jiri ya tụnyere otu ndị e si agwọ ọrịa ciprofloxacin.

Nsonaazụ ndị a na-atụ aro na galiki nwere ike ịnye ma antimicrobial na mgbochi mkpali, yana mmetụta synergistic na ciprofloxacin.

Ndị ọrịa nwere ọrịa prostatitis na-a Cụ Cifran na-eme mkpesa banyere nsonaazụ ndị dị ka ọgbụgbọ (2.5%), afọ ọsịsa (1.6%), vomiting (1%), na ihe ọkụ (1%).

Etu ị ga-esi were okwu "Tsifran":

Ndụmọdụ a na-atụ aro okenye sitere na 250 mg ruo 750 mg ugboro abụọ kwa ụbọchị. Dabere n’ụdị ọrịa a ga-agwọ, ịnwere ike ị were Cifran site ụbọchị 3 ruo 28.
Site na cystitis na-adịghị agbanwe agbanwe, usoro ọgwụgwọ dị ụbọchị 3, na-enwe ụdị dị ala ma ọ bụ nke siri ike
Na urethritis, usoro ọgwụgwọ ga-ewe site ụbọchị asatọ ruo ụbọchị iri.
Na otitis media, tonsillitis, tonsillitis, usoro ọgwụgwọ bụ,,, nkezi, 5 ụbọchị.
N'ihe banyere ọrịa eriri afọ, dabere ogo ya, ọgwụgwọ ahụ na-ewe ụbọchị asaa ruo ụbọchị 28.
Ọgwụ "Tsifranom" ọrịa urinary tract
Site na ọrịa na ọnya nkwonkwo, ọ nwere ike ịdị mkpa iji "Tsifran" ruo ọnwa.
Ekwesighi iji ata ndị ahụ ata ata;
Enwere ike iburu mbadamba cifran na nri ma ọ bụ na afọ efu.
Ọ bụ ezie na enwere ike iri nri nri nwere nri gụnyere mmiri ara ehi, a notụghị ọgwụ ahụ naanị mmiri ara ehi ma ọ bụ jiri nri nwere calcium sie ike.
Can enweghị ike ị antụ ọgwụ antacids, mmeju na calcium, magnesium, iron ma ọ bụ multivitamins awa 6 tupu ma ọ bụ awa 2 mgbe ị gachara "Tsifran"

Otu esi ewere "Tsifran" intravenly:

Ọkọlọtọ N'ezie nke infusion therapy (ọgwụgwọ na intravenous solution) "Tsifran" na nnukwu ọrịa
N'ime oge ụfọdụ, a na-enye “Tsifran” obere oge (site na nkeji 30 ruo otu awa).
Ngwunye nke Tsifran nwere 0.9% w / v sodium chloride solution.
Faịlị ahụ dakọrịrị na mmiri nsị.

"Tsifran": usoro ogwu maka ndị okenye na ụmụaka, ọnụahịa yana analogues nke ọgwụ

Treatmentzọ ọgwụgwọ yana ọgwụ Cyfran ga-adabere n'ụdị ọrịa nje.

Usoro ọgwụgwọ dọkịta nyere ga-agbaso nwere ike ịdị iche na nke edepụtara n'isiokwu ahụ.

Soro ntuziaka dọkịta n’ezie.

"Tsifran": ọgwụ maka ndị okenye:

Nnukwu sinusitis (dị nro ma ọ bụ agafeghị oke): 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ 400 mg ugboro abụọ infusion kwa ụbọchị (intravenously) maka ụbọchị 10. Site na onu ogugu nke iji "Tsifran" di iche na a na-enye ogwu ahu site n'aka igwe okwu.
Ọkpụkpụ nkwonkwo na nkwonkwo (dị nro ma ọ bụ agafeghị oke): 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ nze 400 mg ugboro abụọ kwa ụbọchị maka ụbọchị iri atọ.
Ọrịa prostatitis na-arịa ọrịa na-adịghị ala ala (dị nro ma ọ bụ agafeghị oke). A na-egosipụta usoro onunu ogwu maka ọrịa prostatitis na-adịghị ala ala nke Escherichia coli ma ọ bụ Proteus Mirabilis: 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ nze 400 mg ugboro abụọ kwa ụbọchị maka ụbọchị 28.
Mgbasa ozi otitis na-adịghị ala ala: 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ ngbanye 400 mg ugboro abụọ kwa ụbọchị maka
Ọrịa afọ ọsịsa: 500 mg ugboro abụọ kwa ụbọchị maka
Ọkpụkpụ akwara umeji (obere ma ọ bụ na-adịghị ala ala): 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ ntụtụ 400 mg ugboro abụọ kwa ụbọchị maka otu izu ma ọ bụ abụọ.
Ọrịa nke akpụkpọ anụ ahụ (dị nwayọọ ma ọ bụ agafeghị oke): 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ mg mg 400 ugboro abụọ kwa ụbọchị maka otu izu ma ọ bụ abụọ.
Ọrịa ọnya na - ebute ọnya (dị nro / na - agbakọghị): 250 mg ugboro abụọ kwa ụbọchị maka ụbọchị 3.
Ọrịa Ureral na gonococcal (anaghị agbakọta): otu ugboro.
Anthrax, usoro ọgwụgwọ na mbufụt: 500 mg ugboro abụọ kwa ụbọchị ma ọ bụ ntụtụ 400 mg kwa ụbọchị maka ụbọchị 60.

A na-edenye ndị agadi agadi ọrịa mbadamba Cyfran. A na-agbakọta usoro onunu ogwu dabere n'ịdị ogo nke ihe mgbaàmà ya na ihe ịrịba ama nke ọrịa ahụ, yana nwechapụ ya. Dịka ọmụmaatụ, ọ bụrụ na ihe ngosi a sitere na 30 ruo 50 ml / min, dose nke Cyfran sitere na 250 ruo 500 mg ugboro abụọ n'ụbọchị.

“Tsifran” abụghị nhọrọ izizi na ọgwụ ụmụaka (ma e wezụga ọrịa anthrax), n'ihi mmụba ugboro ugboro nke mmetụta nsonaazụ (gụnyere ọrịa ogbu na nkwonkwo) ma e jiri ya tụnyere ndị na-ahụ maka njikwa. Enweghị data dosing maka ndị ọrịa ụmụaka nwere ọdịda akụrụngwa.

"Tsifran": usoro onunu ogwu maka umuaka site na afo ise rue 17:

Pulmonary anthrax (usoro ọgwụgwọ ọrịa n'azụ oge).
Ngwọta maka infusion: na ọnụego 10 mg / n'arọ, ugboro abụọ n'ụbọchị, maka ọnwa abụọ. Ọgwụ mmadụ n'otu n'otu ekwesịghị ịkarị 400 mg.
Mbadamba ụrọ: na ọnụọgụ 15 mg / n'arọ, ugboro abụọ n'ụbọchị maka ọnwa abụọ, ọgwụ mmadụ n'otu n'otu ekwesịghị ịkarị 500 mg.
Ọgwụ Cystic fibrosis.
Mbadamba ụrọ: na ọnụego 40 mg / kg / ụbọchị, ugboro abụọ n'ụbọchị. Ọgwụ otu onye ekwesịghị gafere 2 g / ụbọchị.
Ngwọta maka infusion: n'arọ / ụbọchị, awa asatọ ọ bụla. Ọgwụ otu onye ekwesịghị ịfe 1.2 g / ụbọchị.

Nnukwu ịba ụba nke ciprofloxacin nwere ike ibute mmebi akụrụ.

Na ihe omumu banyere anumanu, imeru oke ogwu diprofloxacin kpatara nsogbu iku ume, vomiting, na ahuhu.

Analogs nke "Tsifran":

Mpempe akwụkwọ Baycip - 500 mg. Emeputa - Bayer.
Mbadamba Cebran - 500 mg. Emeputa - Blue Corss.
Mbadamba Ciplox - 500 mg. Emeputa - Cipla.
Mbadamba Ciprowin - 500 mg. Emeputa - Alembic Pharma.
Mbadamba alcipro - 500 mg. Emeputa - Alkem Labs.
Mbadamba Cipronat - 500 mg. Emeputa - Natco Pharma.
Mbadamba Ciprofen - 500 mg. Emeputa - Franklin Labs.
Mbadamba Ciprobid - 500 mg. Emeputa - Cadila Pharma.
Mbadamba ụrọ - 500 mg. Emeputa - Torrent Pharma.
Dobe ntị na anya "Betaciprol" - 0.3%. Emeputa - Beta Lek.
Ngwọta Ọgwụ Ificipro - 2 mg / ml. Emeputa - UNIQUE PHARMACEUTICAL Laboratories.

Pricegwọ nke "Tsifran" dị na ụlọ ahịa ọgwụ dị iche iche na Russia dị iche na 51 rubles (maka mbadamba 10 nke 250 mg nke ọ bụla) na 92 rubles (maka mbadamba nkume nwere usoro 500 mg nke ọ bụla).

Costgwọ nke "Tsifran" n'ụdị nke ihe eji egbochi ntụtụ bụ site na 44 ruo 56 rubles.

Ọnụahịa "Tsifran" n'ụdị ọdịda anya bụ site na 48 ruo 60 rubles.

Mwepụta wepụtara ya na ihe mejupụtara

Sdị usoro iji wepụta Tsifran ST - mbadamba mkpuchi nwere: mbadamba 250 mg + 300 mg - edo edo, oval, mbadamba nkume 500 mg + 600 mg - edo edo, oval, n’akụkụ ya na eriri nkewa (na ngwugwu nke 1, 2 ma ọ bụ 10 blisters 10 pcs.).

Ihe dị n'ime 1 mbadamba:

ciprofloxacin - 250 ma ọ bụ 500 mg (dị ka hydrochloride monohydrate),
Tinidazole BP - 300 ma ọ bụ 600 mg.

isi: sodium lauryl sulfate, sodium starch glycolate, microcrystalline cellulose, silikion anhydrous, magnesium stearate,
mmiri nke mpụta akwa nke granules: sodium sitashi glycolate, talc dị ọcha, sodium lauryl sulfate, microcrystalline cellulose, silikion nke anhydrous, magnesium stearate,
shei: odo Opadry, mmiri dị ọcha.

Mlọ ọgwụ

Cifran ST bụ otu n'ime ihe ndị a ejikọtara ọnụ nke ndị na - arụ ọrụ ya - tinidazole na ciprofloxacin - na - eji ya agwọ ọrịa nke nje microorganisms nke anaerobic na anaerobic kpatara.

Njirimara nke ihe ndị dị n'ọrụ:

Mlọ ọgwụ

Ihe ndị na-arụ ọrụ na-etinye obi gị dum na eriri afọ. Oke kasịnụ (C_max) a na-enweta ihe ọ bụla mejupụtara n'ime awa 1-2.

Bioavailability bụ 100%, ihe jikọrọ protein ndị dị na plasma bụ ihe dịka 12%. Iwepu ọkara ndụ na-anọ site na awa ruo awa iri na anọ.

Ọ na - abanye n’ime akwara nke anụ ahụ ngwa ngwa wee rute nnukwu ebe ahụ.Ọ na-abanye na mmiri akụkụ ụbụrụ dị n'ime mkpo ya na mkpokọta plasma ya, na-enwetakwa ntụgharị na akwara renal.

Ọ bụ ihe adịkarịpụrụ adịkarị obere ka ọ dị ntakịrị karịa 50% n'ime ọbara ya. Ihe dị ka 25% nke ọgwụ a isụrụ na-apịpụta akụrụ na-agbanweghi. Tinidazole metabolites dị ihe dịka 12% nke ndị enyerela maka ya; akụrụ na-emepụtakwa ya. Na mgbakwunye, a na-ewepụ obere tinidazole site na eriri afọ.

Ciprofloxacin

Mgbe nchịkwa ọnụ gasịrị, ọ na-etinye obi gị dum. Bioavailability dị ihe dịka 70%. N'iji nri, imeghari ihe n'otu oge jiri nwayọ were nwayọ. N'agbata 20 na 40% nke ciprofloxacin na-ejikọ protein protein.

Ọ na - abanye n’arụ na anụ ahụ - anụ ahụ, ngụgụ, abụba, klaasị, akwara na akwara, yana n’ime akụkụ nke sistem mkpụrụ ndụ, tinyere gland prostate. A na - achọta mmiri dị elu nke ciprofloxacin na mmiri, azịza nke imi, imi, lymph, mmiri peritoneal, mmiri seminal, na bile.

Ciprofloxacin na-mejupụtara akụkụ imeju ya. Ihe dị ka 50% nke ọgwụ ahụ ka akụrụ na-agbanweghi agbanwe, 15% - n'ụdị metabolites ndị na-arụ ọrụ, ọkachasị, oxociprofloxacin. Fọm nke fọrọnị ka ọpịputere na bile, na -akuku ikegharị. Site na akwara gbasara akwara, ihe dị ka 15% ruo 30% nke ọgwụ a na-akpọ agwọprofloxacin. Nkera nke ndụ bụ ihe dịka awa 3.5-4.5.

N'ebe ndị ọrịa agadi nọ ma nwee nnukwu nsogbu gbasara akụrụ, ọkara ndụ nwere ike ịdị ogologo.

Ihe ngosi maka ojiji

Dịka ntuziaka ahụ si dị, Edere Tsifran ST maka ọgwụgwọ nke nje nje ndị na-esochikọta anya nke microorganisms gram-positive / gram na-emetụta, na njikọ yana anaerobic na microorganisms aerobic na / ma ọ bụ protozoa:

Ọrịa ENT: sinusitis, otitis media, tonsillitis, pharyngitis, mastoiditis, frontal sinusitis, sinusitis,
Ọrịa anụ / adụ anụ ahụ: ọrịa ọnya, ọnya anụ ahụ ọnya afọ na-arịa ọrịa mamịrị n'ụkwụ, ọnya, akwa, akwara, ọnụnọ, akwara,
ọrịa nke onu ura: periodstitis, periodontitis, nnukwu ọnya afọ gingivitis,
ofufe ọrịa nke akụkụ ahụ na akụkụ ahụ, gụnyere yana trichomoniasis: salpingitis, tubular abscess, pelvioperitonitis, oophoritis, endometritis, prostatitis,
ọrịa metụtara ọkpụkpụ na nkwonkwo: osteomyelitis, ọrịa ogbu na nkwonkwo,
eriri afọ: eriri afọ, ọrịa fever ịba, amoebiasis,
Ọrịa urinary na ọrịa akụrụ: cystitis, pyelonephritis,
gbagwojuru anya intraal ime,
Ọrịa nkwonkwo nke ala: ọrịa na-adịghị ala ala (n'oge ọrịa) bronchitis, bronchiectasis, poniaonia,
oge nke ịwa ahụ (mgbochi ọrịa).

Ihe ngbanwe

ọrịa ọbara, mgbochi nke ụmị ọkpụkpụ
ọnya anụ ahụ nke sistem,
nnukwu porphyria
enweghị lactose, ụkọ lactase, glucose-galactose malabsorption,
ngwakọta ọgwụgwọ na tizanidine (ejikọtara ya na mbelata ọbara mgbali elu na mmepe nke iro ụra).
afọ ruo afọ 18
ime na lactation,
ndị mmadụ ịnabata ọgwụ ndị metụtara ọgwụ, yana fluoroquinolones na imidazoles.

Ikwu (Tsifran ST họpụtara n’okpuru nlekọta ahụike):

ọghọm nke ụbụrụ,
ọnya anụ ahụ na ọgwụgwọ fluoroquinolone gara aga,
oké ụbụrụ arteriosclerosis,
ọrịa obi (infarction myocardial, obi nkụda mmụọ, bradycardia),
congenital ịgbatị nke oge QT,
electrolyte ahaghioke, tinyere hypokalemia, hypomagnesemia,
isi mgbaka
oke akwara / akwara dara ada,
Akwụkwụ na-adọ, ọrịa na-efe efe,
na-ejikọ ọgwụgwọ na ọgwụ nke na-agbatị oge QT, gụnyere ọgwụ antiarrhythmic nke klaasị IA na III,
ngwakọta ọgwụgwọ na ndị na-egbochi CYP4501A2 isoenzymes, gụnyere theophylline, methylxanthine, caffeine, duloxetine, clozapine,
nká.

Ntuziaka maka iji Tsifran ST: usoro na usoro onunu ogwu

Ejiri ọnụ mmiri a na-ewere Cifran ST na mmiri, ọ ka mma ka ị gachaa nri. Chew, tiwara ma ọ bụ bibie mbadamba nkume ekwesịghị.

Dọkịta Ọkacha atụ aro nke Tsifran ST:

250 mg + 300 mg: mbadamba nkume abụọ ugboro abụọ kwa ụbọchị,
500 mg + 600 mg: ugboro 2 kwa ụbọchị maka mbadamba 1.

Nsonaazụ

sistemu ụjọ: vertigo, isi ọwụwa, dizzness, nhazi nke mmegharị (gụnyere locomotor ataxia), dysesthesia, hypesthesia, hyperesthesia, paresthesia, disorientation, ọgba aghara, dysarthria, oke ike ọgwụgwụ, nkwarụ, ịma jijiji, adịghị ike, akwara neuropathy, ehighi ura, ọgba aghara, ụra abalị, mgbali intracranial dị ukwuu, akwara ụbụrụ, nkụda mmụọ, isi ọwụwa, nchekasị, ịda mba, obi mgbawa, yana ngosipụta ndị ọzọ nke mmeghachi omume psychotic. na (mgbe ụfọdụ ọ na - aga n'ihu n'ọnọdụ onye ọrịa nwere ike imerụ onwe ya ahụ), polyneuropathy, paralgesia,
sistem nri: nri aguu, xerostomia, uto di na onu, ime n’afo, ahuhu, oria, inochi, oria, oria n’onu, oria, ekpomoku, oria cholestatic (tumadi n’ebe ndi oria nwere oria na mbu).
sisitemu obi: wedata ọbara mgbali elu, ọgba aghara nke obi, tachycardia, ịgbatị oge nke QT na electrocardiogram, ventricular arrhythmias (gụnyere ụdị Pirouette),
sistem hematopoietic: granulocytopenia, leukocytosis, ọrịa serum, hemolytic anemia, neutropenia, agranulocytosis, vasodilation, pancytopenia, inhibition nke ụmị ọkpụkpụ, thrombocytosis, thrombocytopenia, leukopenia, anaemia,
akụkụ anụ ahụ: anụrị isi / ụtọ, tinnitus, ịnụ ụfụ / ọnwụ, nhụjuanya anya (n'ụdị diplopia, mgbanwe nke ịma mma nke agba, ịba ụba fotoensitivity),
usoro iku ume: nsogbu nke iku ume (nke gụnyere bronchospasm),
Usoro urinary: njigide nke urinary, polyuria, ọdịda akụrụ, interstitial nephritis, hematuria, belatara oke ọrụ excretory nke akụrụ, crystalluria (yana mbelata mmamịrị na mmamịrị alkaline), glomerulonephritis, dysuria,
usoro akwara: mwepu nke mgbaàmà nke myasthenia gravis, ụda olu na-arịwanye elu, akwara olu, ọrịa ogbu na nkwonkwo, tendovaginitis, ogbu na nkwonkwo, myalgia, ike ọgwụgwụ,
paramitaị laboati: hypercreatininemia, hyperglycemia, hyperbilirubinemia, hypoprothrombinemia, ụba ọrụ nke amylase, alkaline phosphatase, transpeases hepatic,
mmeghachi omume nfụkasị: urticaria, pruritus, usoro nke blisters, nke ọbara ọgbụgba na-esonyere ya, na obere nodules na-esochi akpọnwụ, ọnya ọbara na akpụkpọ ahụ (petechiae), fever fever, laryngeal / ọdịdị ihu, mkpụmkpụ ume, vasculitis, eosinophilia, erythema nodosum, toxic epidermal necrolysis (ọrịa Lyell), erythema multiforme exudative (gụnyere ọrịa Stevens-Johnson syndrome), ujo anaphylactic, mmeghachi omume anaphylactic,
ndị ọzọ: ọsụsọ mụbara, ịmịcha ihu, asthenia, superinfection (gụnyere pseudomembranous colitis, candidiasis).

Dodoụbiga ya ókè

Enweghị ọgwụ mgbochi akọwapụtara, yabụ, ọ bụrụ na ị doụbiga ya ókè, egosipụtara ọgwụgwọ ọgwụgwọ, gụnyere usoro ndị a: lavage gastric ma ọ bụ iwetuta ọgbụgbọ, usoro iji hichaa ahụ nke ọma (ọgwụ infusion), yana ọgwụgwọ nkwado.

Site n'enyemaka nke usoro hemo- ma ọ bụ mgbapụta, a pụrụ iwepụ tinidazole kpamkpam site na ahụ, ciprofloxacin na obere ego (ihe dị ka 10%).

Ntụziaka pụrụ iche

N'oge a na-eme ọgwụgwọ, a na-atụ aro izere ikpughe ọkụ karịa anwụ, ebe enwere ohere mmepe nke mmeghachi omume phototoxicity. N'ihe banyere ọdịdị ha, akagbuola Tsifran ST ozugbo.

Iji belata ohere nke kristalia, ọ gaghị ekwe omume gafere ọgwụ akwadoro kwa ụbọchị. Ọzọkwa, onye ọrịa ahụ kwesịrị ịchọpụta na mmiri ga-ezuru ya na mmezi nke mmeghachi omume mmamịrị acidic. Theakingụ ọgwụ ọjọọ ahụ na-akpata mmachi mmamịrị gbara ọchịchịrị.

N'ọnọdụ ndị a na-adịghị ahụkebe, n'oge usoro ọgwụgwọ, a na-ahụta mmepe nke nsogbu ndị dị ka urticaria juputara, iwetulata ọbara mgbali, mbufe ihu / larynx, dyspnea na bronchospasm. Ọ bụrụ na ị nwere ihe nfụkasị ọ bụla maka irighiri akịzozole, ịmara tinidazole nwere ike ịpụta, ọdịdị nke mmeghachi ahụ nfụkasị nri na ciprofloxacin nwekwara ike hụrụ na ndị ọrịa nwere nfụkaghị ikike ndị ọzọ fluoroquinolone. Ya mere, n'ọnọdụ ebe onye ọrịa ahụ chọpụtara mmepe mmeghachi omume nfụkasị ọ bụla na ọgwụ ndị yiri ya, mmadụ ga-eburu n'uche ohere nke mmeghachi omume nfụkasị Cyfran ST.

N'oge usoro ọgwụgwọ, ọ dị mkpa iji nyochaa onyonyo nke ọbara mpaghara.

Mkpokọta ojiji nke Cifran ST na mmanya na-egbu egbu, n'ihi na yana nchikota tinidazole na mmanya, ọnya afọ, ọgbụgbọ, na ọgbụgbọ nwere ike ịmalite.

Na-emegide usoro nke Akwụkwụ na-adọ, akụkọ banyere nsogbu nke ihe ọdịdọ, ọrịa vaskụla na mbibi ụbụrụ nke nje, enwere ike iji Tsifran ST naanị maka ebumnuche ahụike, nke ejikọtara ya na iyi egwu nke mmeghachi omume ọjọọ site na sistemụ akwara etiti.

Emebebeghị ike / nchekwa nke iji Tsifran ST maka ọgwụgwọ na mgbochi nke ọrịa anaerobic n'ime ụmụaka na-erubeghị afọ 12.

Ọ bụrụ na afọ ọsịsa na-adịte aka ma ọ bụ ruo ogologo oge malitere mgbe / mgbe usoro ọgwụgwọ, pseudomembranous colitis kwesịrị iwepu, nke chọrọ iwepụ ọgwụ ozugbo na nhọpụta ọgwụgwọ kwesịrị ekwesị.

N'ihe banyere ihe mgbu na akwara ma ọ bụ ngosipụta nke ihe ịrịba ama mbụ nke tenosynovitis, a na-ahapụrụ nchịkwa nke Cyfran ST.

Mkparịta ụka ọgwụ ọjọọ

anticoagulants na-apụtachaghị ìhè: a na-eme ka mmetụta ha dịkwuo mma, iji belata ike ọbara ọgbụgba, belata belata ahụ site na 50%,
ethanol: a na-eme ka mmetụta ya dịwanye mma, ma eleghị anya mmepe nke mmeghachi omume disulfiram.
ethionamide: nkwanye akwadoghi
phenobarbital: a na-eme ka metabolism nke tinidazole gbasie ike.

Enwere ike iji Tinidazole mee ihe na njikọ nke sulfonamides na ọgwụ nje (erythromycin, aminoglycosides, rifampicin, cephalosporins).

Emeputa

Ihe eji eme ihe: ciprofloxacin hydrochloride 297.07 mg, nke dika hoprofloxacin 250 mg.

Ndị pụrụ iche: microcrystalline cellulose 25.04 mg, ọka ọka 18.31 mg, magnesium stearate 3.74 mg, talc 2.28 mg ọcha, colloidal anhydrous silicon 4.68 mg, sodium starch glycolate 23.88 mg, mmiri dị ọcha * q.s.

Ihe mpempe ihe nkiri: Opadray-OY-S58910 ọcha 13.44 mg, talc 1.22 mg, ọcha talc q.s., mmiri dị ọcha.

Omume ọgwụ

Ọgwụ nje na - egbochi nje bacteria, nje na - egbochi ihe nje.

Ọ na - egbochi mkpịsị ugodi nke nje bacteria na - akpaghasị njikọ nke nje bacteria, na - eduga n'ọnwụ nke mkpụrụ ndụ nje ahụ.

Ewebata ngwa ngwa site na eriri afọ, ọnụnụ bioavailability nke ihe dị ka 70%. Mgbe otu ọgwụ 250 na 500 mg, nkezi nkezi serum bụ 1.5 na 2.5 μg / L, n'otu n'otu, ọtụtụ oge gafere MPC90 maka ọtụtụ microorganisms. Mgbe nchịkwa iv nke 200 mg, ịta ahụ ọbara bụ 3.8 μg / ml. Haziri kesara wee nweta ọgwụgwọ anụ ahụ n'ọtụtụ akwara na mmiri. Ọnọdụ njikọ njikọ protein dị ala (19-40%). A na - agbanwe ya na mmamịrị ya, yana ihe ọnya na ọnya.

Ọrịa ọnya afọ, ọrịa ọgbụgbọ, oyi baa, akpụkpọ ahụ na anụ ahụ dị nro, ọnya anụ ahụ na nkwonkwo, ọrịa nke eriri afọ, ọka bali, nsị ọbara.

Mmekorita

Site na iji doanosine na-eme ya n'otu oge na ciprofloxacin, a na-ebelata mmetụta nke ciprofloxacin n'ihi nguzobe nke ciprofloxacin na aluminom na magnesium salts dị na didanosine.

Nlekọta oge nke ciprofloxacin na theophylline nwere ike ibute mmụba na mkpokọ theophylline na plasma ọbara n'ihi mgbochi asọmpi na saịtị nke cytochrome P450, nke na-eduga n'ịba ụba na ndụ ọkara nke theophylline na mmụba nke ihe ndị dị egwu nsonaazụ metụtara theophylline.

Nlekọta nke imeju nke abụba, ọgwụ antacids, ọgwụ nwere ikike nkwupute ya (dịka ọmụmaatụ, ọgwụ antiretroviral), yana ọgwụ nwere aluminom, zinc, iron ma ọ bụ magnesium ion, nwere ike ibute mbelata nke mkpụrụ osisi ciprofloxacin, yabụ a kwesịrị iwere ciprofloxacin ma ọ bụrụ 1-2 awa tupu ma ọ bụ 4 awa mgbe ị drugsụsịrị ọgwụ ndị a.

Mmachi a anaghị emetụta ọgwụ antacids nke ndị otu H2 receptor blockers.

Ekwesịrị iji zoo ojiji nke ciprofloxacin, ngwaahịa mmiri ara ehi ma ọ bụ ihe ọ mineralụ mineralụ siri ike ịnweta (dịka mmiri ara ehi, yogọt, ihe ọ orangeụ orangeụ oromaziri wusiri ike), ebe ọ bụ na enwere ike belata mmịpụta nke ciprofloxacin. Agbanyeghị, kalịnda, nke bụ akụkụ nke nri ndị ọzọ, anaghị emetụta mmịpụta nri nke ciprofloxacin.

Site na iji ciprofloxacin na omeprazole jikọtara ọnụ, enwere ike ịbelata ntakịrị mkpokọta (Cmax) nke ọgwụ na plasma ọbara na mbelata mpaghara n'okpuru usoro nlebara oge (AUC).

Nchikota otutu onunu na quinolones (gyrase inhibitors) na ufodu ogwu na - ebuso steroidal (ewepu acetylsalicylic acid) nwere ike ibute oria.

N'iji oge nke ciprofloxacin na anticoagulants (gụnyere warfarin), oge ọbara na-agbatịkwu.

N'iji oge nke ciprofloxacin na cyclosporine, a na-eme ka mmetụta nephrotoxic nke nke ikpeazụ na-eme ka ọ dịkwuo mma. Site na usoro ọgwụgwọ oge na ciprofloxacin na cyclosporine, a hụrụ mmụba dị mkpirikpi na plasma creatinine ịta. N'ọnọdụ ndị dị otú a, ọ dị mkpa iji chọpụta mkpokọta nke creatinine n'ime ọbara ugboro abụọ n'izu.

N'ọnọdụ ụfọdụ, ojiji nke ciprofloxacin na glibenclamide nwere ike ịkwalite mmetụta nke glibenclamide (hypoglycemia).

Nchịkọta ọgwụ nke uricosuric ọgwụ, gụnyere probenecid, na -ebelata ọnụego nke mkpochasị nke ciprofloxacin site na akụrụ (ihe ruru 59%) ma na-eme ka ịba ụba nkeprofloxacin na plasma ọbara.

Site na nchịkwa oge nke ciprofloxacin, ụgbọ njem tubular (metabolism metabolism) nke methotrexate nwere ike belata, nke enwere ike ibute mmụba nke methotrexate na plasma ọbara. N'ụdị a, ohere ndị methotrexate nwere ike ịmụba. N'akụkụ a, ndị ọrịa na-anakọta ọgwụgwọ na ọgwụ methotrexate na ciprofloxacin kwesịrị ilebara anya nke ọma.

Metoclopramide na-eme ka ahụike nkeproprololocin kwụsịlata, na -ebelata oge dị mkpa iji wee nwee ike itinye uche na plasma ọbara. N'okwu a, bioavailability nke ciprofloxacin anaghị agbanwe.

N'ihi ọmụmụ ihe ọmụmụ banyere ndị ọrụ afọ ofufo nwere ahụike na oge nke ciprofloxacin na tizanidine, ekpughere mmụba nke tizanidine na plasma ọbara: ekpughere mmụba na Cmax site na oge asaa (site na oge 4 ruo 21), mmụba na AUC site ugboro 10 (site na 6 ruo 24 ugboro). Site na mmụba nke mkpokọ tizanidine n'ọbara ọbara, a na-ejikọ mmetụta hypotensive na ọgwụ na-egbochi nsogbu. Yabụ, iji ọgwụ ahụ a na - ejikọ ciprofloxacin na tizanidine.

Enwere ike iji Ciprofloxacin yana ọgwụ nje ndị ọzọ.Dịka e gosipụtara na ọmụmụ vitro, ojiji ọgwụ mgbochi ciprofloxacin na ọgwụ β-lactam, yana aminoglycosides, bụ ndị mmụba na enweghị mmetụta, mmụba na mmetụta nke ọgwụ abụọ ahụ adịkarịghị ụkọ, ọ dịkwa ụkọ ntakịrị.

Etu ị ga-esi, usoro nchịkwa na usoro onunu ogwu

N'ime, na afọ efu, na-enweghị ita, ya na obere mmiri mmiri. Enwere ike iwere ya n’ebighi gbasara nri. Ọ bụrụ na a na-eji ọgwụ ahụ na afọ efu, a na-etinye ihe ahụ na-arụ ọrụ ngwa ngwa. Na nke a, ekwesighi iji mmiri ara ehi mepụta mbadamba ihe ma ọ bụ nke nwere calcium (dịka ọmụmaatụ, mmiri ara ehi, yogọt, ihe ọ juụ juụ nwere nnukwu calcium). Calcium achọtara na nri nri anaghị emetụta nnabata nke ciprofloxacin.

Ọgwụ nke ciprofloxacin na-adabere n'ịdị ogo nke ọrịa, ụdị ọrịa ahụ, ọnọdụ ahụ, afọ, ibu na ọrụ akụrụ na onye ọrịa. Usoro ọgwụgwọ a tụrụ aro:

Ọrịa nke akụkụ okuku ume na ala (akwara na-adịghị ala ala (na nnukwu usoro) bronchitis, poniaonia, bronchiectasis, na-efe efe na-emetụta cystic fibrosis) dị nwayọ ruo ogo na-agafeghị oke - 500 mg ugboro abụọ kwa ụbọchị, n'ọnọdụ dị egwu - 750 mg 2 ugboro n'ụbọchị. Ọgwụgwọ ya bụ ụbọchị 7-14.

Ọrịa nke akụkụ LOP (otitis media, nnukwu sinusitis) - 500 mg ugboro abụọ kwa ụbọchị, usoro ọgwụgwọ bụ ụbọchị iri.

Ọrịa nke ọkpụkpụ na nkwonkwo (osteomyelitis, ọrịa ogbu na nkwonkwo) - dị nwayọọ ruo ogo na-adịghị mma - 500 mg ugboro abụọ kwa ụbọchị, n'ọnọdụ dị egwu - 750 mg ugboro abụọ. Usoro ọgwụgwọ ya dị ka izu isii na isii.

Ọrịa nke anụ ahụ yana anụ ahụ dị nro (ọnya na-arịa ọrịa ọnya, ọnya, ọkụ, ọnya, phlegmon) nke dị nro ruo na-agafeghị oke - 500 mg ugboro abụọ kwa ụbọchị, n'ọnọdụ dị egwu - 750 mg ugboro abụọ n'ụbọchị. Ọgwụgwọ ya bụ ụbọchị 7-14.

Campylobacteriosis, shigellosis, afọ ọsịsa nke "ndị njem" - 500 mg ugboro abụọ kwa ụbọchị, usoro ọgwụgwọ bụ ụbọchị 5-7.

Ọrịa Typhoid - 500 mg 2 ugboro n'ụbọchị maka ụbọchị 10.

Ọrịa afọ na-efe efe (yana yana metronidazole) - 500 mg ugboro abụọ kwa ụbọchị maka ụbọchị 7-14.

Ọrịa akụrụ na ọnya afọ (cystitis, pyelonephritis) - 250 mg, gbagwojuru anya - 500 mg ugboro abụọ n'ụbọchị. Ọgwụgwọ ya bụ ụbọchị 7-14. Ọrịa cystitis na-agbadighi n'ime ụmụ nwanyị - 250 mg ugboro abụọ kwa ụbọchị maka ụbọchị 3.

Ọkpụkpọ na-agbakọ - 250-500 mg otu ugboro.

Ọrịa prostatitis na-adịghị ala ala - 500 mg 2 ugboro n'ụbọchị, usoro ọgwụgwọ - ụbọchị 28.

Ọrịa ndị ọzọ (lee mpaghara “Ihe Na-egosi”) - 500 mg 2 ugboro n'ụbọchị. Septicemia, peritonitis (ọkachasị bu ọrịa Pseudomonas, Staphylococcus ma ọ bụ Streptococcus) - 750 mg ugboro abụọ n'ụbọchị.

Mgbochi na ọgwụgwọ nke ọrịa mbufụt - 500 mg 2 ugboro n'ụbọchị maka ụbọchị 60.

Na usoro ọgwụgwọ nke ndị ọrịa agadi, ekwesịrị iji usoro ọgwụgwọ nke syprololoxacin dị ala, dabere na ọrịa ahụ na mkpochapụ creatinine (dịka ọmụmaatụ, na mwepụ nke creatinine nke 30-50 ml / min, ọgwụ a na-atụ aro nke ciprofloxacin bụ 250-500 mg kwa elekere 12).

Maka ọgwụgwọ nke ọrịa pulmonary cystic fibrosis nke Pseudomonas aeruginosa nwere n'ime ụmụaka gbara afọ 5 ruo 17, a na-eji ọnụ ede 20 mg / n'arọ ibu 2 ugboro / ụbọchị. (opekata mpe ya 1500 mg). Oge ọ dị n'ọgwụgwọ bụ 10-14 ụbọchị.

Maka mgbochi na ọgwụgwọ nke anthrax, 15 mg / kg body body 2 ugboro / ụbọchị ka a na-edebere ya ọnụ (ọnụọgụ otu otu ekwesịghị ịkarị - 500 mg yana kwa ụbọchị - 1000 mg).

Theụ ọgwụ ahụ kwesịrị ịmalite ozugbo ọrịa ahụ kwuru ma ọ bụ gosipụtara na ọ bụ oria.

Oge ngụkọta oge nkeproprololoxacin n'ụdị ọrịa anthrax bụ ụbọchị 60.

Ntụziaka pụrụ iche

Achọpụtara ya na ciprofloxacin, dị ka ọgwụ ọgwụ ndị ọzọ nke klas a, na-akpata ọrịa ogbu na nkwonkwo buru ibu na anụmanụ. Mgbe ị na-enyocha data nchekwa ugbu a maka ojiji nke ciprofloxacin na ụmụaka na-erubeghị afọ 18, nke ihe ka ọtụtụ nwere ọrịa akwara fiystosisi, ọ nweghị njikọ dị n'etiti mmebi nke cartilage ma ọ bụ nkwonkwo na ị theụ ọgwụ ahụ. ngụgụ (na ụmụaka sitere na afọ ise ruo afọ iri na asaa) jikọtara ya na Pseudomonas aeruginosa yana maka ọgwụgwọ na mgbochi nke ọrịa ọgụ na-efe efe (mgbe enyochisịrị ma ọ bụ ọrịa egosipụtara na ọ bụ ọrịa Bacillus anthracis).

Na outpatient ọgwụgwọ nke ndị ọrịa na-efe efe nke bacteria nke Pneumococcus, ciprofloxacin ekwesịghị iji dị ka ọgwụ nke mbu.

N'ọnọdụ ụfọdụ, mmeghachi omume na-adịghị mma site na sistemụ akwara nwere ike ime mgbe ejiri ọgwụ mbụ were. N'okwu ndị na-adịghị ahụkebe, psychosis nwere ike igosipụta onwe ya na ọnwụnwa igbu onwe ya. N'ụdị ndị a, ojiji nke ciprofloxacin kwesịrị ịkwụsị ozugbo.

N'ime ndị ọrịa nwere akụkọ ihe mere eme nke ọdịdọ, akụkọ banyere ọdịdọ, ọrịa vaskụla, na ụbụrụ ụbụrụ na-akpata n'ihi iyi egwu nke mmeghachi omume akwara site na sistemụ akwara etiti, ekwesịrị ka a na-edenye ciprofloxacin naanị maka "ihe ngosi dị mkpa", na ọnọdụ ebe atụ anya na-elele ụlọ ọgwụ ga-ekwe omume ohere nke mmetụta ndị ọzọ. ọgwụ.

Ọ bụrụ na afọ ọsịsa ma ọ bụ nke ogologo oge na-apụta n'oge ọgwụgwọ ma ọ bụ mgbe ọgwụgwọ jiprofloxacin gasịrị, a ga-ewepụ ihe nchoputa nke ọrịa prọfesọ nke pseudomembranous, nke chọrọ iwepụ ọgwụ ozugbo na ịhọpụta ọgwụgwọ kwesịrị ekwesị.

Ihe ọgwụ ndị na-egbochi imeju afọ anaghị egbochi ya. Ndị ọrịa, ọkachasị ndị bu ọrịa imeju, nwere ike ịrịa ọrịa cholestatic jaundice, yana mmụba nwa oge na ọrụ nke “imeju” transaminases na alkaline phosphatase.

Achọrọ nnabata usoro usoro ọgwụgwọ kwesịrị ekwesị mgbe ị na-edepụtara ndị ọrịa ọgwụ gbasara akụrụ na oke ịba ọcha n'anya.

Mgbe ụfọdụ, mgbe ị takingụsịrị ọgwụ izizi mbụ nke ciprofloxacin, mmeghachi omume nfụkasị ahụ nwere ike ime, adịkarịghị anaphylactic ujo. Ceptionmata ciprofloxacin na nsogbu ndị a ga-akwụsị ozugbo ma ekwesịrị ịme ọgwụgwọ kwesịrị ekwesị.

N'ebe ndị ọrịa agadi nọ mesoro glucocorticosteroids, enwere ike ịnwe ikpe mmebi nke akwara Achilles.

Ọ bụrụ na enwere ihe mgbu na akwara ma ọ bụ mgbe ihe ịrịba ama mbụ nke tendonitis pụtara, a ga-akwụsị ọgwụgwọ n'ihi eziokwu ahụ bụ na ikpe ndị dịpụrụ adịpụ na ọbụna mgbawa nke akwara n'oge a na-akọwa fluoroquinolones.

N'oge ọgwụgwọ ciprofloxacin, a ga-ezere kọntaktị na ìhè anyanwụ, ebe ọ bụ na a ga-emeghachi mmeghachi omume na fotoproitiiti. Ekwesịrị ịkwụsị ọgwụgwọ ma ọ bụrụ na a hụrụ mgbaàmà nke ịbelata ọgwụ (dịka ọmụmaatụ, mgbanwe na akpụkpọ ahụ yiri anwụ anwụ).

A maara Ciprofloxacin ka ọ bụrụ onye na - egbochi obere ihe CYP1A2 isoenzyme.

Ekwesịrị ịkpachara anya mgbe ị na-eji ciprofloxacin na ọgwụ ọgwụ ndị a na-akpọ isoenzyme, dịka theophylline, methylxanthine, caffeine, n'ihi mmụba na mkpokọta ọgwụ ndị a n'ọbara ọbara nwere ike ibute nsonaazụ ndị kwekọrọ na ya.

Iji zere mmepe nke kristalia, ọ bụ ihe a na-anabataghị gafere mmiri ọgwụ a na-atụ aro kwa ụbọchị, ịmịcha mmiri zuru oke (na-emetụta usoro diureis nkịtị) yana idozi mmeghachi omume nke acidic dịkwa mkpa.

Na ọrịa na-efe efe na mkpụrụ ndụ ọnya, nke a na-ebute nje na-emetụta mmiri Neisseria gonorrhoeae na-efe efe, a ga-eleba anya na ozi dị na nguzogide ciprofloxacin na ekwesịrị ịnagide nje ahụ na teCmax laabu.

Mmetụta ikike ịkwọ ụgbọala, usoro:

Ndị ọrịa na-ewere ciprofloxacin kwesịrị ịkpachara anya mgbe ị na-anya ụgbọ ala ma na-etinye aka n'ihe omume ndị ọzọ dị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi omume psychomotor.

Usoro onunu ogwu na nhazi

Edere cifran n'ụdị ihe ngwọta maka infusion ka n’ọnọdụ ndị ọrịa enweghị ike ị pụ ọgwụ. Mgbe emechara ọnọdụ onye ọrịa ahụ, ekwesịrị ịfe ya n'ụdị ọgwụ ọgwụ ahụ.

Ana mburu mbadamba nkume ndị ahụ ọnụ, jiri mmiri mmiri zuru ezu sachaa. O kwere omume iji ọgwụ ahụ n'agbanyeghị nri nri, mana mgbe ewere ya na afọ efu, a na-etinye ihe na-arụ ọrụ ngwa ngwa, ị gaghị a drinkụ ọgwụ ahụ na ngwaahịa mmiri ara ehi ma ọ bụ ihe ọ drinksụ fortụ nwere calcium. Calcium dị n’ime nri anaghị emetụta mmịpụta nke ọgwụ.

Aro maka usoro ogwu nke ogwu a:

Ọrịa dị ala nke akụkụ okuku ume: 500 mg ugboro abụọ kwa ụbọchị (maka ọrịa dị nfe na agafeghị oke), 750 mg ugboro abụọ kwa ụbọchị (maka ọrịa siri ike), maka ụbọchị 7-14,
Ọrịa ENT: 500 mg 2 ugboro n'ụbọchị, maka ụbọchị 10,
ofufe ọrịa nke ọkpụkpụ na nkwonkwo: 500 mg ugboro abụọ n'ụbọchị (maka obere ọrịa nfe na-agafe agafe), 750 mg ugboro abụọ kwa ụbọchị (maka ọrịa siri ike), maka izu isii,
nsonaazụ nke anụ ahụ na anụ ahụ dị nro: 500 mg ugboro abụọ n'ụbọchị (maka obere ọrịa nfe na-agafe agafe), 750 mg ugboro abụọ kwa ụbọchị (maka ọrịa siri ike) maka ụbọchị 7-14,
campylobacteriosis, shigellosis, afọ ọsịsa ndị njem: 500 mg ugboro abụọ n'ụbọchị maka ụbọchị 5-7,
oria ojoo: 500 mg 2 ugboro kwa ubochi, ubochi iri,
nsogbu dị n’ime afọ ime: 500 mg ugboro abụọ n’ụbọchị ruo ụbọchị 7-14,
Ọria akụrụ na akwara ọnya: 250 mg ugboro abụọ n’ụbọchị (maka oria na - abaghị uru), 500 mg ugboro abụọ n’ụbọchị (maka ihe mgbagwoju anya) maka ụbọchị 7-14, cystitis na - agbakọ n’ime ụmụ nwanyị - 250 mg ugboro abụọ n’ụbọchị maka ụbọchị 3. ,
gonorrhoea (na-esighi ike): 250-500 mg ewere otu ugboro,
ọrịa prostatitis na-adịghị ala ala: 500 mg 2 ugboro n'ụbọchị maka ụbọchị 28,
sepsis, peritonitis: 750 mg ugboro abụọ n'ụbọchị,
mkpụrụ ume (mgbochi na ọgwụgwọ): 500 mg ugboro abụọ n'ụbọchị maka ụbọchị 60.

Maka ọrịa ndị ọzọ, ọgwụ a tụrụ aro bụ 500 mg ugboro abụọ kwa ụbọchị.

Ndị okenye merela agadi kwesịrị iji ọgwụ ole na ole belata ya (ọgwụ ahụ dabere n'ịdị ọcha nke ọrịa ahụ na ikpochapụ ya).

Ihe Cyfran ji eme ihe banyere umuaka:

nsogbu ndị Pseudomonas aeruginosa kpatara, megide ndabere nke ọrịa akwara fibrosis na ụmụaka 5-17 afọ: 20 mg / n'arọ 2 ugboro n'ụbọchị, oke kachasị - 1500 mg, maka ụbọchị 10-14,
mkpụrụ ọgwụ na-efe efe (prophylaxis na ọgwụgwọ): 15 mg / n'arọ 2 ugboro n'ụbọchị, kacha otu ugboro bụ 500 mg, kwa ụbọchị bụ 1000 mg, maka ụbọchị 60 (a ga-amalite usoro ọgwụgwọ ozugbo enwere ike mgbe ọrịa ahụ kwuru ma ọ bụ gosipụtara).

Ndị ọrịa nwere nsogbu gbasara akụrụngwa:

na nwechapụ nke creatinine (CC) nke 31-60 ml / min, oke ọgwụ kwa ụbọchị bụ 1000 mg (250-500 mg kwa elekere 12 ọ bụla),
na CC na-erughị 30 ml / min, ọgwụ kachasị maka ọgwụ kwa ụbọchị bụ 500 mg (250-500 ugboro na awa 18).

Ndị ọrịa na hemodialysis kwesịrị ị heụ ọgwụ ahụ mgbe usoro a gasịrị.

N'ihe banyere ọrụ imeju na-emebi emebi, achọrọ imeghari dose nke Cyfran.

Ọgwụ ka a ga-aga n’ihu n’ime opekata mpe ụbọchị 3 mgbe mgbachapụ nke ihe mgbaàmà ọrịa ahụ gwụsịrị.

Ndụmọdụ maka oge ọgwụgwọ Cifran:

gonorrhoea (na-esighi ike): 1 ụbọchị,
immunodeficiency: n'oge dum nke neutropenia,
ọrịa osteomyelitis: oge kachasị maka ọgwụ ahụ bụ ụbọchị 60,
ọrịa ndị ọzọ: izu 1-2,
streptococcal na-efe efe: opekempe nke ọgwụgwọ bụ ụbọchị iri.

Ngwunye infusion

Iji gbochie mmetụta ndị na-adịghị mma na saịtị infusion, a na-atụ aro ka Cifran banye n’ime nnukwu akwara ọ dịkarịa ala minit 60.

Nyere ọgwụ ahụ dabere ogo ọrịa ahụ, ụdị ya, ọnọdụ onye ọrịa ahụ, afọ ya na oke ahụ ya, yana ọrụ akụrụ.

Usoro a tụrụ aro:

akụkụ okuku ume na-efe efe: 400 mg 2-3 ugboro kwa ụbọchị, dabere ogo ọrịa ahụ.
ọrịa nke usoro mkpụrụ ndụ: 200-400 mg ugboro abụọ kwa ụbọchị (nnukwu, enweghị mgbakwunye, dịka ọmụmaatụ, gonorrhea), 400 mg 2-3 ugboro kwa ụbọchị (ihe mgbagwoju anya, dịka prostatitis, adnexitis), mg mg ugboro anọ kwa ụbọchị (nke na-eyi ndụ egwu na ọkachasị Ọrịa siri ike, dị ka sepsis, peritonitis, ọrịa nke ọkpụkpụ na nkwonkwo),
mkpụrụ ume: 400 mg ugboro abụọ n’ụbọchị (maka ndị okenye), 10 mg / kg 2 ugboro n’ụbọchị (maka ụmụaka), oke otu kacha - 400 mg, kwa ụbọchị - 800 mg, maka ụbọchị 60 (bido ọgwụgwọ ngwa ngwa o kwere mee. mgbe enyochiri anya ma obu enyocha oria),
ọrịa ndị ọzọ: 400 mg ugboro abụọ kwa ụbọchị, n'ihe banyere nnukwu ofufe ọrịa - ugboro atọ kwa ụbọchị, maka izu 1-2, ọ bụrụ na ọ dị mkpa, mmụba na oge ọ nọ na ọgwụgwọ ga-ekwe omume.

Ndị ọrịa nwere nsogbu gbasara akụrụngwa:

na CC 30-60 ml / min, ọgwụ kachasị elu kwa ụbọchị bụ 800 mg,
na CC erughi 30 ml / min, ọgwụ kachasị elu kwa ụbọchị bụ ọgwụ 400 bụ mg.

Ọgwụ ka a ga-aga n’ihu n’ime opekata mpe ụbọchị 3 mgbe mgbachapụ nke ihe mgbaàmà ọrịa ahụ gwụsịrị.

Ndụmọdụ maka oge ọgwụgwọ Cifran:

gonorrhoea (na-esighi ike): 1 ụbọchị,
immunodeficiency: n'oge dum nke neutropenia,
ọrịa osteomyelitis: oge kachasị maka ọgwụ ahụ bụ ụbọchị 60,
ọrịa ndị ọzọ: izu 1-2,
streptococcal na-efe efe, ọrịa nke chlamydia kpatara: opekempe nke ọgwụgwọ ahụ bụ ụbọchị iri.