Captopril Sandoz bụ angiotensin na - agbanwe enzyme inhibitor. N’ikwu ya n’ụzọ ọzọ, ọgwụ ahụ na-egbochi ụdị nke abụọ nke angiotensin ịgbanwe n’ime nke mbụ. N'ihi ya, mbelata dị ukwuu na homonụ oligopeptide na-eme ka ọ̀tụ̀tụ̀ ọbara ji erugharị ghara ịdị mma. N'itinye usoro ziri ezi, onye ọrịa ahụ na-eme ọ bụghị naanị ọbara mgbali, kamakwa ngụkọta ngụgụ nke akwara. Mmetụta hypotensive nke ọgwụ ahụ nwere onwe ya kpamkpam na ọrụ plasma renin. Ndị ọrịa na-enwe mbelata nke nrụgide ọbụlagodi na mkpokọta homonụ nkịtị. Ọ nwere ike ịkwalite mgbasa ọbara site na arịa ọbara nke myocardium. Dabere na ntuziaka maka ojiji, Captopril Sandoz belata adhesion platelet, nwere ihe na - egbochi uto nke nkụda obi, yana na - agbadata mmụba nke olu nke oghere aka ekpe. A na-etinye ọgwụ ahụ ngwa ngwa na eriri afọ. Ihe ngosi ndị a dịkarịa ala 75%. Ndị ọrịa kwesịrị icheta na ị simụkọta nri na oge ị reducesụkọ nri na ọgwụ a na --eme ka mmetụta nke ihe mejupụtara belata belata ọkara. A na-ewepụta akụkụ bụ isi nke ihe ndị ahụ site na ịrụ ọrụ akụrụ kwesịrị ịrụ mana naanị obere akụkụ ya na-agbanwe agbanwe.

Ọ bụ dọkịta pụrụ iche ka a na-edobe Captopril Sandoz, mgbe ọ gafesịrị ule niile dị mkpa. Ezubere ya maka ndị ọrịa nwere ọtụtụ ọrịa ndị na - esote: • ọbara mgbali elu, ọbara ọgbụgba renovascular, ihe kpatara ya bụ mbelata nke akwara pere mpe ma ọ bụ alaka ya, • emeghasị ventricle aka ekpe, nke jikọtara ya na myocardium gara aga, • mmebi akụrụ n'ihi nguzobe chọpụtara na ọrịa shuga mellitus, • nkụda obi na-adịghị ala ala. Ọ dị mkpa iburu n'uche na ọgwụ ahụ achọpụtala iji ọgwụ eji eme ọfụma ọ bụghị naanị dịka monotherapy, kamakwa dịka akụkụ nke ọgwụgwọ dị mgbagwoju anya. Ndị ọrịa kwesịrị ịghọta na ọ bụrụ na itinyeghị mkpa kwesịrị ekwesị na ahụike gị, mgbe ahụ oke ọbara ọgbụgba nwere ike inye nsonaazụ dị oke njọ. Mwepu nke na-edugharị mmadụ na nnuku ya na-eduga mmadụ imezu ìsì. Ọkpụkpụ mkpụrụ ndụ na-agwụ ike, ọrụ obi na-aka njọ, nke na-eme ka ọnwụ dịkarịa ala ugboro ise. Mmụba na shuga ọbara na-emetụta sistemụ akwara, nke ga-esi ike iweghachi. Mmebi akụrụ na-aga n’ihu kwa ụbọchị na-eji ọbara mgbali elu.

Ngwakọta na ụdị ọgwụ ahụ

Ngwakọta bụ isi nke Captopril Sandoz bụ ihe dị otu aha. Ihe ndi ozo n’ime ihe mejuputara bu microcrystalline cellulose, sitirika nduku, lactose monohydrate, yana stearic acid. Ngwaahịa ndị German dị naanị n'ụdị mbadamba n'ahịa ọgwụ. Unitlọ nke ọ bụla nwere agba gburugburu ma dịkwa mma ma, dabere na usoro onodu ogwu a, nwere ike were otu okwute ma obu akwukwo ahihia. Mbadamba ụrọ ahụ na-acha ọcha na agba ọcha. Uwe a na-ahụ anya na ndò, ọ bụghị naanị na elu oyi akwa, kamakwa na ngalaba. N’aka otu, enwere ihe ọghọm maka ịgbaji dị mma. Ọgwụ inhibitory dị na usoro nke 6.25 mg, 12.5 mg, 25 mg, 50 mg na 100 mg. Ihe ndozi dị otú a na-eme ka ọ dị mfe ịgbanwe usoro a na-eme kwa ụbọchị maka ndị ọrịa. Mbadamba ụrọ ọ bụla dị na ụlọ ihe eji eme nri. Kpootu nke ọ bụla nwere nkeji iri. Nkwakọ kaadiboodu nwere ike ịnwe sel otu na mkpụrụ ndụ iri.

Ihe ngbanwe

Ọgwụ ọ bụla, agbanyeghị mpaghara eji ya, ọ bụghị naanị aha egosi, kamakwa nyocha nke machibidoro usoro ọgwụgwọ. Ntụziaka maka iji Captopril Sandoz na-ekwu na ọgwụ a isenyeghị ndị ọrịa nwere ọtụtụ ọrịa ndị a: • ekweghị ibe ya n'otu akụkụ nke ihe mejupụtara ya, yana ịba ọcha n'anya, • na-ahụkarị ihe mmeghachi ahụ, gụnyere angioedema, gosipụtara na mpaghara buru ibu , • mụbara ọdịnaya nke ngwaahịa metabolic na ọbara n’ime ahụ, eweputara ya n’akụrụ akụrụ, • ịba ụba potassium n’ime ọbara, • akụkụ akụkụ ma ọ bụ mmechi nke akwara akwara. Enwere m mkpụrụ osisi aorta, valvụ mital ma ọ bụ akụrụ, • n'oge oge mgbake mgbe ebugharị akụrụ, • syndromes na-etolite n'ihi nsonaazụ aldosterone, • ọnụnọ nke ihe mgbochi ọpụpụ ọbara site na ventricle aka ekpe, • ọbara mgbali elu, • mgbagha nke infarction myocardial, nke Ọtụtụ mgbe ọ na-egbu egbu, • ojiji nke ọgwụ a n'otu oge yana ọgwụ ndị sitere na aliskiren. Ọ bụrụ na onye ọrịa nwere nsogbu ọ bụla site na listi ndị a dị n'elu, dọkịta ahụ depụtara analog na-akụ afọ n'ala.

Dika otutu ihe omumu banyere ya na nyocha, a gha agharo Captopril Sandoz ihe dika otu awa tupu nri. Ọ ka mma ịghara ata ata ma drinkụọ mmiri dị ọcha. Ekwesịrị ị nweta usoro onunu ogwu dị mkpa maka otu okwu ahụike nke ndị ọkachamara n'ihe banyere ọgwụ ahụ. Enwere usoro ọgwụgwọ oge ochie nke onye nrụpụta gosipụtara. Ọ dị mma ka onye ọrịa malite iji usoro ọgwụgwọ nke 12.5 mg na-amalite oge ahụ. A na-anabata nnabata ugboro abụọ n'ụbọchị. Mgbe onye ọrịa ahụ takesụsịrị ọgwụ nke mbụ, dọkịta kwesịrị iji nlezianya nyochaa ọnọdụ ahụ n'ime awa mbụ. Ọ bụrụ na mmadụ nwere obi ụtọ, na nke a enweghị ọgwụ contraindications maka iji ọzọ. Maka ọgwụgwọ dị irè karị, dọkịta mgbe a na-agwọ ya nwere ike ịhazigharị usoro kwa ụbọchị ma n'otu ụzọ na akụkụ nke ọzọ. Maka ndị ọrịa ahụ chọrọ ọgwụgwọ dị nwayọọ ma na-akwado ya, ọ ga-abụ ihe dị mma ị takeụ 25 mg n'otu oge. Oke kachasị kwa ụbọchị na nke a agaghị agafe 50 mg. Ọ bụrụ na ọ dị mkpa, dọkịta na-abawanye ruo 150 mg, nke kewara n'ime usoro atọ kwa ụbọchị. A ga-elezi ndị ọrịa na-arịa ọrịa obi anya ma jiri nlezianya hụ dọkịta. Omenala, na oria yiri ya, dibia na-atụ aro ịmalite ọgwụgwọ site na usoro onunu ogwu nke 6.25 mg. Site na mgbanwe dị mma na enweghị nsonaazụ ndị ọzọ, enwere ike idozi dose ahụ.

Nsonaazụ

Tupu ịmalite ị aụ ọgwụ, ị kwesịrị iji nlezianya mata onwe gị na nsonaazụ ọjọọ ndị ọrịa ga-enwe. N'ezie, Captopril Sandoz bụ akara nke mmepe na teknụzụ ọgbara ọhụrụ. Agbanyeghị, enwere ọnụọgụ ngosi ndị a: • mbelata ọnụ ọgụgụ nke neutrophils, leukocytes, platelet, eosinophils na glucose, • mmụba dị ukwuu na akwara lụba, • mgbakasị ahụ na arụ ọrụ nke sistem, mgbe anụ ahụ gị hụrụ ka ala ọzọ wee malite imebi ahụ gị n’onwe ya, • mmụba na potassium n'ọbara, • imebi ọ bụghị naanị ihi ụra, kamakwa ọ bụ ihe ụtọ, tinyere ọrịa isi ọwụwa, iro ụra, nkụda mmụọ, na steeti nkụda mmụọ, ndị ọrịa nwere ike ịnwe nsụ na nkụda mmụọ, nkụda mmụọ, na ọnya, • ọnya obi na-egbu mgbu, ihe na-adịghị mma ugboro ugboro na ogologo oge nke obi obi, tinyere ọkụ na-ekpo ọkụ ihu, ma ọ bụ akụkụ ọzọ, yana edere akụkụ, , • mgbakasị ahụ n'ime afọ n'ụdị ọgbụgbọ, na ịda mbà n'obi, • imebi ugboro ole oche blọọgụ, • ọdịdị nke obere ọnya ahụ n'ọnụ nke chee na ire. Ọ bụrụ na onye ọrịa ahụ, na-enweghị ihe ọmụma banyere dọkịta, amụbawo ọgwụ kwa ụbọchị, ọ dị mkpa iji mepụta usoro ọgbụgba dị mkpa ozugbo enwere ike, wepụta ihe ọ bụla na-anabata ihe ma nyekwa ọgwụ nkwado Symptomatic.

Mkparịta ụka ọgwụ ọjọọ

Tupu ịzụta Captopril Sandoz, ị kwesịrị ịghọta na ọgwụ a abụghị "ọyị enyi" n'ụzọ niile. Ọgwụ ndị dị otua nke ndị na - egbochi ọgwụ adịghị akwadoro ka ewere ya n'otu oge yana ọgwụ ndị na - emetụta usoro renin-angiotensin na ahụ mmadụ. E kwesiri icheta na ụdị tandem ahụ nwere ike ime ka onye ọrịa belata ọbara mgbali elu na ọrụ akụrụngwa na-arụ nnukwu ọrụ. Anakwere nnabata n'otu oge, mana ọ bụ naanị na nlekọta ndị dọkịta na-abịa. Jiri ya na aliskiren na-akwadoro nke ọma ka ndị ọrịa na-arịa nsogbu akụrụ zere, yana ụdị ọrịa shuga 2. Ejikwa ya na nchịkọta potassium dị iche iche kwesịrị izere. Det dị otú a nwere ike kpasu iwe hyperkalemia. Ọ bụrụ na enweghị ike iwepu nchikota a, n'ọnọdụ a onye ọrịa kwesịrị ịnọ n'okpuru nlekọta nke dọkịta n'oge oge niile, na-agafe ule niile dị mkpa. A na-ejide ọgwụ ndị dị na Lithium n'ime ahụ, si otú a na-eme ka ịba ụba nke isi ihe na ọbara mmadụ.

Ntụziaka pụrụ iche

Captopril Sandoz bụ ọgwụ dị oke njọ, ọ ga-ejikwa otu mmụọ bịaruo ya nso. Ọ dị mma, tupu ịmalite usoro ahụ, nyochaa nrụgide ahụ ruo ọtụtụ izu n'usoro iji ghọta oke yana n'okpuru ọnọdụ ndị ụfọdụ egosi. Ihe onyonyo yiri ya di nkpa na usoro ozo. Akụkụ bụ isi nke ihe mejupụtara ahụ nwere ike ibute data ụgha mgbe ị na-ebufe mmamịrị na acetone. N'okwu a, ọ ga-ebu ụzọ ịkwụsị ị itụ ya na mgbe ụbọchị ole na ole gachara ịmeghachi ule ahụ. Ruo oge usoro ọgwụgwọ niile, onye ọrịa ahụ ga-ahapụ ịkwọ ụgbọala ahụ, yana mmemme dị iche iche chọrọ itinye uche pụrụ iche. Nlezi anya kwesiri ka ndị ọrịa ahụ na-arịa ọrịa site na anụ ahụ na njikọ, yana ọnụnọ nke usoro mkpali na mgbidi nke arịa ọbara. Site na mgbaàmà ọ bụla na-enyo enyo, ekwesịrị ịkagbu nsonye ọgwụ ahụ ozugbo enwere ike ịhọrọ ndị yiri ya.

Nzipu ederede na ihe mejuputara

Odikwa na mbadamba nkume, nwere agwa ndia:

• udi ahu di okirikiri ma obu uzo nke akwukwo
• agba ọcha
• Ngwakọta mebere
• ihe egwu no na uzo abuo ma obu abuo.

A na-eji ihe dị iche iche mepụta ihe dị na ya. Ngalaba mwepụta, dosed na 6.25, 12.5, 100 mg, nwere ọdịdị gbara okirikiri. N’ụdị akwụkwọ anọ, ụdị nwere 50 na 25 mg nke ihe na-arụ ọrụ dị.

Enokwara n'ime blisters maka nkeji usoro 10. A na-ahapụ ha na ngwugwu kaadiboodu. A na-etinye Ntụziaka ahụ.

Releaselọ obibi ọ bụla nwere ihe ndị na-arụ ọrụ na-arụsi ọrụ ike nke ngwa nri na ihe enyemaka. Ihe mejupụtara ọgwụ ndị ọzọ:

• ọka ọka
• lactose monohydrate,
• microcrystalline cellulose,
• stearic acid.

Containnwekọta ogige ndị na-emerụ ahụ, na-enye nsonaazụ ọgwụgwọ dị mkpa.

Captopril Sandoz

Captopril Sandoz: ntuziaka maka ojiji na nyocha

Aha Latin: Captopril Sandoz

Koodu ATX: C09AA01

Ngwakọta ọrụ: captopril (Captopril)

Onye na-emepụta: Salutas Pharma, GmbH (Salutas Pharma, GmbH) (Germany)

Na-emelite nkọwa na foto: 07/12/2019

Ahịa dị n'ụlọ ahịa ọgwụ: site na 81 rubles.

Captopril Sandoz bụ ọgwụ antihypertensive, angiotensin na - agbanwe inhibitor enzyme (ACE).

Ndị na-ahụ maka ọgwụ

Ọrịa ọbara mgbali (art- na usoro nkwonkwo), nkụchi obi obi, ọrịa obi, hapụrụ ventricular dysfunction na ọnọdụ kwụsie ike na ndị ọrịa mgbe ọrịa infịction myocardial, nephropathy diabet na ndị nwere ụdị ọrịa shuga 1 (nke nwere albuminuria karịa 30 mg / ụbọchị).

Jiri na agadi

Maka ndị afọ ndụ ha karịrị afọ 60-65, agụmakwụkwọ ahụ ga-amalite site na usoro onunu ogwu nke 6.25 mg ugboro abụọ n'ụbọchị. Ọnụahịa nke Captopril Sandoz bụ 100 rubles. Nwere ike ịzụta ọgwụ ahụ site na ụlọ ahịa ọgwụ dị n'ịntanetị na nnyefe n'ụlọ gị ma ọ bụ ọfịs gị. Ọ na-wepụtara na mgbe ngosi nke uzommeputa.

Akwụkwọ ikike ahịa ọgwụ LO-77-02-010329 nke June 18, 2019

Ọgwụ ọgwụ

Ọ nwere mmetụta hypotensive. Ọ na-egbochi njikọ nke angiotensin II vasoconstrictor na-arụ ọrụ site na hemodynamically na-adịghị arụ ọrụ angiotensin I. Ọ na-ebelata nzuzo nke aldosterone.

Na-akwalite mkpokọta bradykinin, nke na-emetụta njikọ nke vasodilating prostaglandins.

Site n'iji ogologo oge ọ nwere mmetụta cardioprotective:

• na-ebelata tupu- na ebudata,
• na-eme ka ọbara na-agbawanye nke mpaghara myocardium,
• na-abawanye maka ịkwakọrọ akwara
• na-eji nwayọ wedata hyromrophy, dilatation nke ventricle ekpe,
• normalizes diastolic ọrụ.

Ọ naghị akpata reflex tachycardia. Ọ na - eme ka ọbara na - agbakwu, na - eme ka nchịkọta platelet dịkwuo ala.

Izu ike nke ọgwụ maka nkụchi obi anaghị akpata mgbanwe n'ọbara. Nye aka na-abawanye ụda nkeji, na-amụba ịnagide mmega ahụ.

Na-anọpụ iche na-anọpụ iche. Ọ nwere mmetụta nke nwere potassium. Na-emetụta uche nke insulin.

Ọ nwere mmetụta nephroprotective. Dilatation nke akwara mmiri akwara na-enyere aka belata nrụgide intraglomerular. Ọ na-egbochi mmeghachi omume intravaskụba intravaskụla, na-ahazi usoro na ọrụ nke epithelium.

Ọrụ nke usoro renin-angiotensin na-ekwupụta mmepe nke mmeghachi omume mbụ nke anụ ahụ n'ị takingụ ọgwụ.

Mwepụta wepụtara ya na ihe mejupụtara

Ọgwụ dị n'ụdị mbadamba: ọcha, nwere akwa edo, gburugburu, usoro nke 6.25 mg - biconvex, onunu ogwu nke 12.5 mg - convex n'otu aka, n'aka nke ọzọ, nkerisi ihe egwu, onunu ogwu nke 25 na 50 mg - n'ụdị akwụkwọ nwere akwụkwọ anọ, ya na chamfer na ihe iyi udiri n’aja n’akuku abuo, uzo onodu ogugu 100 - nke ozo bu ihe ngbanye, nke ozo nwere udiri oria (10 n’ime blisters, na ngwugwu nke 1, 2, 3, 4, 5 ma obu 10 blisters na ntuziaka maka iji Captopril Sandoz).

Otu mbadamba 1 nwere:

• ihe arụ ọrụ: captopril - 6.25, 12.5, 25, 50 ma ọ bụ 100 mg,
• ihe inyeaka: lactose monohydrate, stachi ọka, microcrystalline cellulose, stearic acid.

Ọgwụ ọgwụ

Ọgwụ nwere ọrụ ndu. Ihe emetụtaghị usoro renin-angiotensin anụ ahụ. A na - ejikọta mmetụta hemodynamic na vasodilation, adabereghị na ọkwa nke renin n'ime ọbara.

Edebere Captopril Sandoz dịka akụkụ nke ọgwụgwọ mgbagwoju anya nke ọbara mgbali elu.

Anọrọ ngwa ngwa. A na - achọpụta mmalite mmalite nke ihe mgbe nkeji iri atọ gachara. Usoro ndu nke ogwu a di elu. Nlekọta ọnụ na-enye nsonaazụ kachasị mgbe elekere 1 gachara. Ogologo oge nke ime ihe sitere na awa anọ ruo n'awa iri na abụọ.

Ọ bụ metabolized na imeju, na-akpụ arụ ọrụ metabolites. Ewepula ya na ụmụ akụrụ. Akụkụ nke ọgwụ ọgwụ ahụ na-agbanwegharị n'ahụ ahụ. Ọ nwere ike ịgbakọ ma ọ bụrụ na arụ ọrụ ezumike arụ ọrụ. Nkera nke ndụ n'ọnọdụ ndị dị otú ahụ na-abawanye ruo otu ụbọchị na ọkara.

Mlọ ọgwụ

Captopril na-enyere aka belata mmepụta nke homonụ angiotensin II site na angiotensin I, nke na-ebelata ntọhapụ nke aldosterone. Nke a na - ebute mbelata ọbara mgbali na ibu na akwara obi.

N'okpuru mmetụta nke ọgwụ ahụ, ọbara ọbara na akwara ọbara na akwara akwara na-abawanye. N'ime ndị ọrịa na-a theụ ọgwụ ahụ ogologo oge, mmịnye ọbara myocardial na-aka mma.

Ọgwụ na-ebelata ihe ize ndụ nke ịrịa ọrịa mamịrị nephropathy.

Ihe na-enyere aka

A na-edenyekarị ya dịka akụkụ nke ọgwụgwọ dị mgbagwoju anya nke ọrịa ndị a:

• ọbara mgbali elu
• ọrịa shuga,
• obi adịghị ala,
• nnukwu akwara ọbara.

Dika monotherapy dị irè na mmalite mbụ nke ọbara mgbali elu akwara, na-aga n’enweghị nsogbu.

Contraindications

Contraindicated na ime, inye nwa. Anaghị etinye ya n'ọrụ na ụmụaka na-erubeghị afọ 18.

Gaghị eji ọgwụ a mee ihe:

• akụkọ banyere angioedema nke mmalite ọ bụla,
• nnabata nke ihe ndi ozo ma obu ogwu ndi ozo.
• ọrịa ọbara
• isi izizi,
• lactose anagideghi, nri nke lactase n’arụ,
• Stenosis nke akwara abụọ nwa ma ọ bụ stenosis nke otu akụrụ.

Agaghị enwe ike iji ọgwụ mmebi ahụ mgbe ọ gbasesịrị akụrụ.

Achọghị Captopril na ụmụaka na-erubeghị afọ 18.

Jiri nlezianya

E kwesịrị ịkpachara anya na ọrịa ndị a:

• ike obara nke obara,
• ọrịa shuga
• scleroderma, lupus eupthematosus,
• mitral valve stenosis, aortic orifice,
• hypovolemia
• umeji akụrụ.

Mgbe ị na-ede ọgwụ, ọ dị mkpa iburu n'uche ojiji nke nri nnu anaghị edozi, nri nri.

Usoro usoro usoro ọgwụgwọ ahụ bụ otu onye. Site na usoro akụrụ gbasara akwara, ọ dị mkpa ilekwasị anya n'ihe ngosipụta nke okike. N'ụdị ndị a, a na-eji usoro ọgwụgwọ dị obere nke dị nta, ogologo oge n'etiti ntụtụ.

Na nrụgide

Ọ dị mkpa ịmalite iji usoro ọgwụgwọ dị obere dị ala, na-achịkwa nnabata nke ọgwụ mbụ. Nenye 12.5 mg ugboro abụọ n'ụbọchị. A na-atụ aro ịrị elu nke nwayọ iji nweta ọkwa ahụ. A na-enye ndị ọrịa ọrịa otu okenye ọgwụ opekata mpe.

N’ime nkụchi obi na-adịghị ala ala, tupu ịmalite ọgwụgwọ, a na-akagbu ma ọ bụ belata ọgwụ ha.

N'okpuru ire ma ọ bụ drinkụọ ihe ọ .ụ .ụ

Uzo ogwu a na-ekpebikwa ya banyere ogo onodu a. Site na ọgwụgwọ a haziri ahazi, a ga-elo ọgwụ ahụ kpamkpam, jiri mmiri zuru ezu were ya.

N'ọnọdụ nsogbu, a na-ahapụ ọgwụ subling.

Ihe omume ogwu a mere ngwa ngwa, mgbe nkeji iri atọ gasịrị. Mmetụta kachasị na nchịkwa ọnụ ka a na-achọpụta n'oge awa mbụ.

Mlọ ọgwụ

Ihe dị ka 75% nke captopril na-anara site na eriri afọ n'ime obere oge. Mana ka ị na-aillụ ọgwụ na nri, mmịbe ahụ na-ebelata ihe dịka 30-40%. A na-ahụta nsonaazụ kachasị nke ihe na-arụ ọrụ n'ime ọbara mgbe awa 0.5-1.5 gachara ọgwụ.

A na-enweta ọgwụ ọgwụ a n'ime imeju. Nkeji ọkara ndụ na-erughị awa 3. Oge a abawanye n’ime ndị ọrịa nwere akụrụ ime.

Ihe na-enyere aka

A na-eji Captopril maka ọbara mgbali elu. Tupu ịmalite ị drinkụ ọgwụ ahụ, a na-atụ aro ịchọpụta ihe kpatara mgbali elu. Oge ụfọdụ ọnọdụ a na-esokarị ọrịa ndị ọzọ, yabụ ịkwesighi ịchọrọ onwe gị ọgwụ. Ọgwụ ka dọkịta ga-edepụtara ya. Ojiji nke ọgwụ ga - ekwe omume na ọkwa ọ bụla nke ọbara mgbali elu.

Edebere Captopril dị ka akụkụ nke usoro ọgwụgwọ mgbagwoju anya maka nkụchi obi nke usoro na-adịghị ala ala. E gosipụtara ọgwụ ahụ maka dysfunction ekpe a na-ekpe, nke kpatara myocardial infarction. A na-adụkwa ndị na-arịa ọrịa shuga ụdị 1 na-arịa ọrịa mamịrị diphropathy ume ị thisụ ọgwụ a.

Akụkụ ahụ hematopoietic

Ogologo oge eji ọgwụ a na mmepe nke neutropenia, thrombocytopenia, yana mbelata nke ọkwa haemoglobin. Mmeghachi omume ndị dị otú a anaghị abịakarị, na-ebufe onwe ha.

Ogologo oge iji ọgwụ a na-agbakwunye mbelata ọkwa Hemoglobin. Mmeghachi omume ndị dị otú a anaghị abịakarị, na-ebufe onwe ha.

N’akpụkpọ anụ ahụ

Theakingara ọgwụ na-ejikarị itching akpụkpọ, ọdịdị nke ihe ahụ ọkụ. Ofụ ọgwụ ogologo oge na-akpata mmepe nke lymphadenopathy. Ọkpụkpụ na-ahụkarị bụ dermatitis na urticaria.

Enwere ihe ọghọm nke ịmalite imebi Quincke edema. Ọdịdị angioedema na larynx na-eyi ihe mgbochi ikuku. Akwụsịla ọgwụ ahụ, a na-enye epinephrine ozugbo, ikuku na-enwetakwa n'efu.

Mgbe ị na-ebu isi mmiri, ị ga-ezere ịkwọ ụgbọala.

Ntuziaka pụrụ iche

Na-eduzi usoro ọgwụgwọ chọrọ nlele oge niile nke usoro akụrụngwa yana ọrụ akụrụ.

Ọ dị mkpa iburu n'uche ohere nke ịmalite hypovolemia mgbe ejikọtara ya na diuretics. Ọnọdụ yiri ya yiri egwu ọrịa akwara, yana ọnwụ.

Iji zere mmepe nke nsogbu na-enyere aka:

• ogwu idozi
• mwepu nke mmalite diuretics,
• normalization nke hemodynamic parameters.

Rens artery stenosis chọrọ titration nke otu ọgwụ, nyochaa ihe usoro nke urinary.

Proteinuria mgbe ị na-eji nnukwu doses na-ebelata ma ọ bụ na-aga n'onwe ya.

Ọ dị mkpa iji zere imekota ọgwụ ọgwụ ndị nwere potassium.

Ejiri nlezianya debe ya maka usoro njikọta anụ ahụ, ọgwụgwọ immunosuppressive. Ọ dị mkpa ịchịkwa ọdịnaya nke mkpụrụ ndụ ọbara ọcha yana sel sel ndị ọzọ.

Ichoro oge ilebara ọkwa glucose ọbara anya.

Mmepe nke cholestatic jaundice, mmụba na titant nke hepatic transaminases chọrọ iwepụ ọgwụ ozugbo.

Ọgwụ ị withụ ọgwụ ya kwụsịrị otu ụbọchị tupu mmalite nke ntinye ịwa ahụ ezubere.

N'ime afọ ime, enweghị ike iji captopril.

Mmanya ndakọrịta

Mmekọrịta na ihe ọ alcoụholicụ na-egbu egbu na-eme ka ọgwụ ọgwụ ahụ ike dịkwuo elu ma na-eme ka ọ ghara ịba uru nke anụ ahụ. Ọnọdụ ndị yiri ya na-etinye mmepe nke ọrịa vaskụla nnukwu.

Iji ihe ọ ofụ alcoụ na-aba n’anya na-eme ka iwepụ potassium n’ahụ ngwa ngwa, na-ewepụ mmetụta dị mma nke ọgwụ ahụ na akwara obi.

Mmanya na-eme ka ọbara ghara ịdị n'ọbara. Ikekwe mmepe nke orthostatic ida.

Overdose nke sandtopril sandoz

Largeakingụ nnukwu ọgwụ ọ causesụ causesụ na-akpata nsogbu akụkụ anụ ahụ, bụ ihe egwu nye ndụ. Mbelata nke ukwuu na mgbapụta nke obi na-esonye a dysfunction nke ventricle aka ekpe, mwepu hemodynamics, na mmepe nke steeti collaptoid. Ihe ịrịba ama nke oke akụrụ odida egosi.

Ọnọdụ a chọrọ nlekọta ahụike mberede. Ọ dị mkpa iji kpochaa afọ. Nye mọ anwansi. Tinyegharịa usoro ọbara, na-eduzi ọgwụgwọ Symptomatic.

Iji ihe na-emekọ ihe ọnụ nwere ike ibute mmepe nke hypotension, mbelata nke protein serum, na hypovolemia.

Nmekorita ya na ogwu ndi ozo

Iji ihe na-emekọ ihe ọnụ nwere ike ibute mmepe nke hypotension, mbelata nke protein serum, na hypovolemia.

Ojiji nke potassium, ihe mgbakwunye nri na-esonyere mmepe nke hyperkalemia na nsogbu nke akụrụ.

Ọ bụ ọgwụ ndị a na - eji ọgwụ mmechi eme ka ọ na-enwe hypotension siri ike.

Ọ gaghị ekwe omume ikpokọta nnabata na Aliskiren na ndị ọzọ ACE inhibitors.

Ngwa ya na Allopurinol na-eduga n'ọdịdị nke neutropenia, na-abawanye ohere nke mmeghachi omume nfụkasị ahụ siri ike.

Mmetụta hypotensive nke ọgwụ ahụ na-akwalite beta-blockers, ndị na-emegide calcium, nitrates, ọgwụ ụra, antipsychotics.

Ọgwụ a na-eme ka ịgwucha digoxin n’ime ọbara.

Enwere ihe ize ndụ nke hypoglycemia mgbe ị na-emekọ ihe na ndị nnọchianya hypoglycemic.

Na -ebilata mkpochapu nke lithium, na-abawanye ohere nke plasma.

Mgbe ị na-emekọrịta na nhazi ọla edo, a na-eme ka mmetụta hypotensive ka mma.

Indomethacin, ibuprofen belata nsonaazụ nke ọgwụ. A na-ahụta mmeghachi omume ndị ọzọ site n'iji ọgwụ estrogen, ọgwụ mgbochi ọnụ, corticosteroids.

Jiri ọgwụ antacids na nri na-ebelata bioavailability nke ọgwụ ahụ na 40%.

Dodoụbiga ya ókè

Ọ bụrụ na agbasoghị ndụmọdụ dọkịta ahụ, ịkagbu Captopril ga - ekwe omume, nke akara ndị a na - egosipụta:

• ọkwa ọbara mgbali elu,
• infarction myocardial,
• ọghọm nke ụbụrụ,
• thromboembolism na nsogbu ya.

Ọrịa chọrọ onye ọrịa.

Usoro na ọnọdụ nchekwa

Ọgwụ ahụ nwere ike iji ya afọ abụọ site na ụbọchị ewepụtara. Enwere ike ịchọta ụbọchị kwekọrọ na nkwakọ ngwaahịa ọgwụ. Mana iji chekwaa njikwa ọgwụ nke ọgwụ, ọ dị mkpa ịnye ọnọdụ nchekwa ziri ezi: ime ụlọ kpọrọ nkụ nke ikuku ikuku anaghị agafe +25 Celsius.

Usoro ahịa ọgwụ ahịa

Nke a bụ ọgwụ ọgwụ.

Otu ngwugwu nwere mbadamba iri abụọ na-akwụ ihe ruru 90 rubles.

Irina Zinovieva, 57 dị afọ, Novocherkassk: “Anọwo m na-arịa ọbara mgbali ogologo oge, ya mere, m nwara ọtụtụ ọgwụ ọgwụ nje, amakwaara m Katopril Sandoz. Ọgwụ na-ebelata ọbara mgbali nke ọma, mana anụ ahụ anabata ya. Mgbe m takingachara ọgwụ ahụ, isi m bidoro merụọ ya ahụ, obi ana-ajọkwa ya njọ, ọnụnọ wee kpọọ nkụ. Ọ dị ọnụ ala, mana anaghị m enye ndụmọdụ ịchekwa ahụike gị. Amaghị m onye ọ bụla ọgwụ a. ”

Maria Kushnareva, onye gbara afọ 49, Novosibirsk: “Ozugbo ị gara ọrụ, otu ọnwa enwere nsogbu zuru ezu. Nrụgide na-abawanye. Otu enyi gwara ya ka ọ gaa Captopril. Ahụike m malitere nke ọma ihe niile ozugbo ewerechara ya. Enweghị mmetụta ọ bụla, ọ bụ ezie na otu enyi dọrọ aka ná ntị na enwere ike ịda ụra ma ọ bụ ihe yiri ya. Ọgwụ dị ọnụ ala, ma na - enyere aka karịa ọtụtụ ọgwụ ọnụ. M na-akwado ya. ”

Ihe ngosi maka ojiji

• ọbara mgbali ike
• Ọbara mgbali elu
• ọrịa obi na - adịghị ala ala - dị ka akụkụ nke usoro ọgwụgwọ mgbagwoju anya,
• dysfunction nke aka ekpe ventricle na ọnọdụ ịgba akwụkwụ ọtọ mgbe infarction myocardial,
• nephropathy na-arịa ọrịa mamịrị na ndị ọrịa nwere ụdị ọrịa shuga 1 nke mellitus (ya na albuminuria karịrị 30 mg / ụbọchị).

Ime na lactation

Ihe ejiri Captopril Sandoz mechie n'oge mmeko na ara.

Mgbe ị na-eme atụmatụ ịtụrụ ime, a ga-akwụpụ ndị na - egbochi ACE (gụnyere isi ala) wee gbanwee na usoro ọgwụgwọ ọzọ na - egbochi nchekwa.

Ọ bụrụ na ịtụrụ ime mere n'oge ọgwụgwọ, ị ga-akwụsị ịbupu Captopril Sandoz ozugbo ma hụ na a na-enyocha onye ọrịa ahụ oge niile maka mmepe nwa ebu n'afọ. Ejikọtara nke a na oke ihe ọghọm nke ịmụpụta ihe ọ bụla dị n’afọ nke nwa ebu n’afọ mgbe ị na-eji ọgwụ n’oge ọnwa atọ nke mbụ nke afọ ime.

Shouldmụ nwanyị toro afọ ga-eme ka a mata ihe egwu dị ukwuu nke ịgwọ ndị na - egbochi ACE n'oge afọ ime metụtara ọrịa na ọnwụ nke nwa ebu n'afọ na / ma ọ bụ nwa amụrụ ọhụrụ. Ogologo oge eji eme ihe a na-ahụ na isi mmalite nke II na III nwere mmetụta na-egbu egbu na nwa ebu n'afọ, na-akpata oligohydramnios, belata ọrụ gbasara akụrụ, yana igbu oge n’ọkpụkpụ ọkpụkpụ nke isi ya. N'ime ụmụ amụrụ ọhụrụ, ọ nwere ike igosipụta onwe ya na ọdịda akwara amụ nwa, hypotension hypotension, hyperkalemia.

N'ime mmiri ara ara, ihe dị ka 1% nke dose of captopril achọtara.

Na arụ ọrụ ezumike ọrụ

Ihe Captopril Sandoz bụ contraindicated na oke nsogbu akụrụ, nsogbu abụọ akụrụ akwara stenosis ma ọ bụ akwara akwara nke otu akụrụ nwere ọrịa azotemia na-aga n'ihu, hyperkalemia, azotemia, na ọnọdụ mgbe akụrụ akụrụ.

Ekwesịrị ịkpachara anya na ọdịda akụrụ nwa, stenosis nke akwara akwara, ma ọ bụ stenosis nke akwara akwara.

Ntọala nchịkwa Captopril Sandoz amalitewo na-eburu n'uche QC.

Nchedo nchekwa

A na-eme ọgwụgwọ n'okpuru nlekọta ahụike mgbe niile. Tupu ọgwụgwọ (izu 1), usoro ọgwụgwọ hypotensive gara aga kwesịrị ịkwụsị. N'ime ndị ọrịa nwere usoro ịba ụba ọbara ọgbụgba, a na-eji nwayọọ nwayọọ mụbaa ọgwụ ahụ kwa awa 24 ruo mgbe a ga-enweta mmetụta kachasị n'okpuru nchịkwa nke ọbara mgbali. N'oge usoro ọgwụgwọ, nleba anya nke ọbara mgbali, onyonyo nke nsogbu (tupu ọgwụgwọ, na ọnwa 3-6 mbụ nke ọgwụgwọ na oge oge mgbe nke ahụ gasịrị ruo otu afọ, karịsịa na ndị ọrịa nwere oke ihe ize ndụ nke neutropenia), ọkwa protein, plasma potassium, plasma potassium, urea nitrogen dị mkpa , creatinine, ọrụ akụrụ, ibu ahụ, nri. Site na mmepe nke hyponatremia, akpịrị ịkpọ nkụ, ọ dị mkpa imezi usoro nke usoro onunu ogwu (mbelata dose). Mgbu ma ọ bụ urticaric (adịghị ala ala) na-apụta n'oge izu anọ mbụ nke ọgwụgwọ, na-apụ n'anya na mbelata nke usoro onyonyo, ịkwụsị ọgwụ na iwebata antihistamines. Negoropenia dose na-etolite n'ime ọnwa 3 mgbe mmalite ọgwụgwọ (a na-ahụkarị ọnụọgụ nke leukocytes n'ime ụbọchị 10-30 wee dịgide ruo ihe dị ka izu abụọ mgbe ịkwụsị ọgwụ ahụ). Ahụhụ (nke a na-ahụkarị na ụmụ nwanyị) na-apụta ọtụtụ mgbe n'ime izu mbụ (site na awa 24 ruo ọtụtụ ọnwa) nke ọgwụgwọ, na-adịgide n'oge ọgwụgwọ ma na-akwụsị ụbọchị ole na ole mgbe njedebe nke ọgwụgwọ ahụ gasịrị. A na - atụgharịghachi mmebi nke uto na oke ịla n’ihu mgbe ọnwa 2-3 gachara. Ọ dị mkpa ịkpachara anya mgbe ị na - eme usoro ịwa ahụ (gụnyere eze), karịchaa mgbe ị na - eji ọgwụ na - agwọ ọrịa izugbe nwere mmetụta dị egwu. Site na mmepe nke ọrịa cholestatic jaundice na ntopute nke necrosis imeju, ọgwụgwọ kwesịrị ịkwụsị. Ọ dị mkpa iji zere hemodialysis site na membranes dị elu nke polyacrylonitrile metaallyl sulfate (dịka ọmụmaatụ, AN69), hemofiltration ma ọ bụ LDL-apheresis (anaphylaxis ma ọ bụ mmeghachi omume anaphylactoid nwere ike ịmalite). Ngwọta ọgwụ na-agwọ ọrịa na-agwọ ọrịa nwere ike ịbawanye ohere nke mmeghachi omume anaphylactic. A na-atụ aro ịhapụ ị beụ mmanya na-egbu egbu n'oge ọgwụgwọ. Jiri ịkpachara anya na-arụ ọrụ maka ndị ọkwọ ụgbọ ala na ndị ọrụ ha jikọtara na itinye uche ha na nlebara anya.