Vasotens H (Vasotens® H)

Vazotens N: Ntụziaka maka ojiji na nyocha

Aha Latin: Vasotenz H

Koodu ATX: C09DA01

Ngwakọta ọrụ: losartan (Losartan) + hydrochlorothiazide (Hydrochlorothiazide)

Onye na-emeputa: Actavis hf. (Iceland), Actavis, Ltd. (Malta)

Nkọwa na nwelite: 07/11/2019

Ahịa dị n'ụlọ ahịa ọgwụ: site na 375 rubles.

Vazotens N bụ ọgwụ ọgwụ jikọtara ọnụ.

Mwepụta wepụtara ya na ihe mebere

Mpempe usoro onunu ogwu - mbadamba ihe eji eme ihe nkiri: okirikiri, biconvex, ya na oria n’azu ma obu ihe ojoo n’otu uzo ozo, n’otu uzo ihe isi di na ya bu akara “LH”, n’akuku ozo - “1” (onunu ogwu 50 mg + 12.5 mg) ma ọ bụ “2” (usoro onunu ogwu nke 100 mg + 25 mg) (na ngwugwu nke pịrị 7, 10 ma ọ bụ 14 PC., n'ime mbadamba 2 ma ọ bụ blister nke mbadamba 7, ma ọ bụ 1, 3, 9 ma ọ bụ blister 10 nke mbadamba 10, ma ọ bụ 1 ma ọ bụ 1 Ihe mgbochi abụọ maka mbadamba 14 na ntuziaka maka iji Vazotenza N).

Ngwakọta 1 mbadamba:

• ngwa ọrụ: potassium losartan - 50 ma ọ bụ 100 mg, hydrochlorothiazide - 12.5 ma ọ bụ 25 mg, karị
• ndị na-ahụkarị: croscarmellose sodium, celclose microcrystalline, mannitol, magnesium, povidone, White Opadrai (hypromellose 50cP, hycromellose 3cP, titanium dioxide, macrogol, cellulose hydroxypropyl).

Mlọ ọgwụ

Vazotens N bụ ọgwụ hypotensive nke ihe mejupụtara.

Njirimara nke bekee dị ike:

• losartan bụ angiotensin II receptor antagonist (ụdị aghụghọ AT1). Na-ebelata ọbara mgbali (BP), ngụkọta akwara ji olu (OPSS), nsogbu na mgbasa akwara, itinye adrenaline na aldosterone n'ọbara, na-ebelata oke ibu, na-enwe nsị diuretic. N'ime ndị ọrịa nwere obi nkụda mmụọ na-adịghị ala ala, ọ na-egbochi mmepe nke ọbara mgbali myocardial ma na-abawanye nnagide mmega ahụ. Ọ naghị egbochi kinase II - enzyme nke na-ebibi bradykinin,
• hydrochlorothiazide bụ thiazide diuretic. Na-ebelata reabsorption nke sodium ion, na-eme ka ntụpọ nke bicarbonate, phosphate na potassium ion dị na mmamịrị ahụ.

Ya mere, Vazotens N na-ebelata olu nke ọbara na-ekesa, na-agbanwe ọrụ nke mgbidi vaskụla, na-eme ka mmetụta nke ganglia dịkwuo ala, belata mmetụta nke vasoconstrictors, si otú ahụ na-ebelata ọbara mgbali.

Mlọ ọgwụ

Mgbe nchịkwa ọnụ gasịrị, losartan na-abanye ngwa ngwa na eriri afọ (GIT). Ejiri ya bioavailability dị ala, akụrụngwa

33% Ọ nwere nsonaazụ nke izizi na-agafe imeju. A na-ahụ ya site na carbonxylation, na-eme ka e guzobe metabolites na-adịghị arụ ọrụ na ihe metabolites na-arụ ọrụ nke ukwuu na-arụ ọrụ (E-3174). Ihe dị ka 99% nke ọgwụ ahụ na-egbochi protein ndị dị na plasma. Mgbe ị nwusịrị Vazotenza N n'ime, a na-enweta mkpokọta kachasị nke losartan n'ime awa 1, metabolite na-arụ ọrụ - awa 3-4._½) losartan - awa 1.5-2, E-3174 - awa 3-4. Ọ na - apụta: site na eriri afọ - 60% nke dose, akụrụ - 35%.

Mgbe nchịkwa ọnụ gachara, hydrochlorothiazide na-abanye ngwa ngwa na ngwangwa nri. Anaghị ime imeju imeju. Ndi_½ - 5.8-14.8 awa. Ọtụtụ (

61%) na-agbanwegharị na mmamịrị.

Ihe ngbanwe

• nnukwu ike ọgwụgwụ ọbara,
• nsogbu QC siri ike (nhichapụ ihe mgbapụta) ≤ 30 ml / min,
• nnukwu ọrịa imeju,
• hypovolemia (gụnyere megide ndabere nke usoro ọgwụgwọ diuretics),
• ngbaka
• afọ ruo afọ 18
• ime na lactation
• hypersensitivity na losartan, hydrochlorothiazide, ihe ndị ọzọ na-esi na sulfonamide ma ọ bụ akụrụngwa inyeaka ọ bụla.

Ekwentị (Vasotens N kwesịrị iji nlezianya mee ya):

• mmebi nke mmiri mmiri elektrik nke mmiri (akpịrị ịkpọ nkụ, hypochloremic alkalosis, hyponatremia, hypokalemia, hypomagnesemia),
• Stenosis abụọ akụrụngwa akwara ma ọ bụ stenosis nke otu akụrụ,
• hypercalcemia, hyperuricemia na / ma ọ bụ gout,
• ọrịa shuga mellitus
• systemic ọrịa nke anụ ahụ jikọrọ ọnụ (gụnyere systemic lupus erythematosus),
• Ibu akụkọ banyere adịghị nfe,
• ụkwara ume ọkụ,
• n'otu oge eji ọgwụ mgbochi na-abụghị ọgwụ steroidal (NSAIDs), gụnyere ndị na-egbochi COX-2 (cyclooxygenase-2).

Nsonaazụ

Mgbe ị na-eji Vazotenza H, nsonaazụ nwere ike ime mgbe ị na-a potassiumụ ọgwụ losartan na / ma ọ bụ hydrochlorothiazide.

Ga-ekwe omume mmeghachi omume:

• sitere na obi obi: mbelata ọbara mgbali elu,
• site na ngwe nri: obere (1%, n'ihi losartan dịka akụkụ nke ọgwụ) - afọ ọsịsa, ịba ọcha n'anya,
• n'akụkụ akụkụ nke iku ume: ụkwara (n'ihi ihe nke losartan),
• akpụkpọ ahụ na mmeghachi omume nfụkasị: urticaria, angioedema (gụnyere ọrịrị nke egbugbere ọnụ, pharynx, larynx na / ma ọ bụ ire), nke nwere ike ibute mgbochi nke akụkụ iku ume, nke a na - adịghị ahụkebe (n'ihi ihe losartan) - vasculitis, gụnyere Ọrịa Shenlein-Genoch,
• plọgum laboratory: adịkarịghị - hyperkalemia (serum potassium> 5.5 mmol / l), mụbara ọrụ nke enzymes imeju.

Site n'ọbara mgbali dị mkpa, ihe na-akacha enwe mmetụta bụ ọgbụgbọ.

Dodoụbiga ya ókè

N'ihe banyere ịdoụbiga mmanya ókè, losartan nwere ike ibute nsogbu ndị a: mbelata ọbara mgbali elu, bradycardia, tachycardia.

Enwere ike igosipụta oke mmiri hydrochlorothiazide site na mfu nke electrolytes (hyperchloremia, hypokalemia, hyponatremia), yana mmiri mmiri na-egbu, nke bụ nsonaazụ nke oke diuresis.

Ọ bụrụ na obere oge agafeela kemgbe ị Vaụ Vazotenza N, a na-atụ aro lavage gastric. Edere Symptomatic na nkwado nkwado, achọrọ mgbazi mmiri-electrolyte nsogbu. Ọ bụrụ na ọ dị mkpa, a na-eme hemodialysis iji wepu losartan na metabolite na-arụ ọrụ na ahụ.

Hydrochlorothiazide

N'oge usoro ọgwụgwọ, ọ dị mkpa iji nyochaa ọnọdụ onye ọrịa iji chọpụta ngwa ngwa akara ngosipụta nke imebi mmiri-electrolyte, nke nwere ike ibute megide mmalite nke afọ ọsịsa ma ọ bụ ọgbụgbọ. N'ime ndị ọrịa, ọ dịkwa mkpa ịchịkwa ọkwa nke electrolytes n'ọbara ọbara.

Ihe akwara nke Thiazide nwere ike igbochi nnabata glucose, nke nwere ike ịchọ ịgbanwetụ nke onye na-ahụ maka hypoglycemic ma ọ bụ insulin.

Hydrochlorothiazide nwere ike belata urinary calcium excretion, yana ime ka obere mkpụkọ episodic na ọkwa calcium. Ọ bụrụ na achọtara hypercalcemia siri ike, a ga-eche na hyperparathyroidism latent.

Thiazides na-emetụta metabolism nke calcium, yabụ, ha nwere ike ịgbaghari nsonaazụ nke ọmụmụ ihe banyere ọrụ nke glands parathyroid. N'akụkụ a, na mgbede nke ule ahụ, a ga-akagbu ọgwụ ahụ.

Hydrochlorothiazide nwere ike ịbawanye triglycerides ọbara na cholesterol.

N'oge ọgwụgwọ, iwe iwe ma ọ bụ mbido nke sistem lupus erythematosus ga-ekwe omume.

Hydrochlorothiazide nwere ike ibute mmepe nke hyperuricemia na / ma ọ bụ gout. Agbanyeghị, losartan, akụkụ nke abụọ na-arụ ọrụ nke Vazotenza N, na-ebelata uric acid ọdịnaya, yabụ, na-ebelata ogo hyperuricemia nke diuretic kpatara.

Na-emegide usoro ọgwụgwọ diuretic, omume nke hypersensitivity omume ga-ekwe omume, ọbụlagodi na ndị ọrịa nwere ọrịa ashma ma ọ bụ allergies.

Mmetụta ikike ịkwọ ụgbọala na usoro dị mgbagwoju anya

Nnyocha ọmụmụ pụrụ iche iji mụọ mmetụta Vazotenza N na-eme na ọgụgụ isi mmadụ na ọrụ psychomotor. Agbanyeghị, n'oge usoro ọgwụgwọ, ure na ụra. Maka nke a, a na-adụ ọdụ ka ị na-arụ ọrụ chọrọ nlebara anya na ọsọ nke mmeghachi omume, ọkachasị na usoro ọgwụgwọ mbụ yana n'oge ịba ụba nke ọgwụ.

Ime na lactation

Mgbe etinyere n’ime oge nke abụọ na nke atọ nke afọ ime, losartan, dịka ọgwụ ndị ọzọ na-emetụta usoro renin-angiotensin-aldosterone (RAAS), nwere ike ibute nkwarụ mmepe ya na ọbụnadị ọnwụ nke nwa ebu n’afọ.

Hydrochlorothiazide na-agafe ihe mgbochi placental, kpebisiri ike n’ọbara nke eriri nwa. Mgbe ejiri ya n’oge ịtụrụ ime, ọ na - ebulite nsogbu nke jaundice n’ nwa ebu n’afọ ma ọ bụ n’amụta nwa, yana thrombocytopenia na nne nwa elebara anya.

Mbadamba mbadamba ụrọ Vasotens N bụ nke a na-egbochi afọ ime. Ọ bụrụ na achọpụtara afọ ime n’oge ị withụ ọgwụ ahụ, ị ​​kwesịrị ịkagbu ya ozugbo enwere ike.

Thiazide diuretics na-abanye n’ime mmiri ara. A na-atụ aro nwanyị ka ọ kwụsị inye ụmụ ya ara ma ọ bụrụ na ọgwụ ike n'oge a na-enye nwa ga-abụ ihe ziri ezi.

Mkparịta ụka ọgwụ ọjọọ

Enwere ike iji Losartan jikọta ya na ndị ọzọ na - egbochi ọgwụ (diuretics, ọmịiko, beta-blockers). N'otu oge ahụ, a na-achọpụta mmekọrịta dị n'etiti nsonaazụ ahụ.

Onweghi nmekorita ogwu nke di egwu banyere ọgwụ nke hydrochlorothiazide, erythromycin, cimetidine, ketoconazole, phenobarbital, warfarin, digoxin.

N'ime ndị ọrịa belata BCC n'ihi ọgwụgwọ e mere ya na nnukwu ọgwụ ịba ọcha n'anya, ọgwụ nwere ike ime ka mbelata ọbara mgbali elu.

Site na iji njikọta nke potassium-sparing diuretics (amiloride, triamteren, spironolactone), potassium nnu ma ọ bụ nkwado potassium, mmụba na ọkwa nke potassium na ọbara ọbara ga-ekwe omume.

Fluconazole na rifampicin belatara ọkwa Plasma nke metabolite na-arụ ọrụ nke losartan. Egosiputaghi uru ulo ogwu a di.

Losartan nwere ike ịbawanye ọdịnaya nke lithium na plasma ọbara. N'akụkụ a, enwere ike ịnye ọgwụ lithium naanị mgbe nyochachara nke ọma banyere uru a na-atụ anya ya na ihe egwu ọ bụla. Mgbe ị na-eji nchikota a, a ga-akpachara anya nyocha plasma nke lithium.

NSAIDs nwere ike belata mmetụta losartan, gụnyere ndị na-egbochi COX-2. N'ime ndị ọrịa nwere nsogbu gbasara akụrụngwa nsogbu, n'ọnọdụ ụfọdụ, njikọ a nwere ike inye aka na akawanye njọ nke ọrụ gbasara akụrụngwa, ruo na mmepe nke nnukwu nsogbu gbasara akụrụ. Mmetụta a na-agbanwegharị.

Ngwakọta na ụdị ntọhapụ

na ngwungwu oyo nke pcs asaa., na ngwungwu kaadiboodu 4 blisters, ma obu ngwugwu nke pcs 14, n'ime ngwugwu kaadiboodu 2 blisters.

na ngwungwu oyo nke pcs asaa., na ngwungwu kaadiboodu 4 blisters, ma obu ngwugwu nke pcs 14, n'ime ngwugwu kaadiboodu 2 blisters.

Mmekorita

Losartan na-eme ka mmetụta nke ọgwụ ndị ọzọ na - egbochi ihe ike ike pụta. Enweghị mmekọrịta dị egwu na hydrochlorothiazide, digoxin, anticoagulants na-apụtachaghị ìhè, cimetidine, phenobarbital, ketoconazole, erythromycin. A kọwo Rifampicin na fluconazole belata ọkwa metabolite na-arụ ọrụ. Achoputaghi uru ulo ogwu nke mmekorita a.

Dị ka ọ dị na nlekọta nke ọgwụ ndị ọzọ na-egbochi angiotensin II ma ọ bụ ihe ọ na-eme, nchịkwa nke oge a na-eme ka ọgwụ ndị na-eme ka ọgwụ pụta (dịka spironolactone, triamteren, amiloride), ịkwado potassium, ma ọ bụ nnọchi nnu nwere mmanụ nwere ike ibute hyperkalemia.

Ndị NSAID, gụnyere Ihe inhibitors COX-2 nwere ike belata nsonaazụ nke diuretics na ihe ndị ọzọ na - egbochi ihe mgbochi.

N’ebe ụfọdụ ndị ọrịa nwere nsogbu gbasara akụrụngwa ndị ejiri NSAIDs gwọọ (gụnyere ndị na - egbochi COX-2), ịgwọ ndị antagonensin II antagonist nwere ike ibute nrụrụ ọrụ ndị ọzọ, gụnyere nnukwu ọrụ gbasara akụrụ, nke a na - agbanwegharịkarị.

Mmetụta antihypertensive nke losartan, dị ka ọgwụ ndị ọzọ antihypertensive, nwere ike ịkụda ike mgbe ị na-ewere indomethacin.

Ọgwụ ndị na-esonụ nwere ike ịmekọrịta thiazide diuretics na nhazi n'otu oge nke ha:

barbiturates, ọgwụ ọjọọ, ethanol - orthostatic hypotension nwere ike ịmị mkpụrụ,

ndị ọrịa hypoglycemic (ndị nnọchite ọgwụ na insulin) - enwere ike ịhazigharị usoro nke ndị na - ahụ ike hypoglycemic.

ọgwụ antihypertensives ọzọ - mmetinye uto ga-ekwe omume,

colestyramine na colestipol - belata oriri nke hydrochlorothiazide,

corticosteroids, ACTH - ụba ọnwụ nke electrolytes, karịsịa potassium,

pressor amines - ikekwe mbelata nke ihe metutara amines na - eme ihe, n’edoghi ya n’iji ha,

anaghị eme ka akwara dị jụụ (dịka ọmụmaatụ tubocurarine) - enwere ike ịkwalite ọrụ nke akwara umeji,

nkwadebe lithium - ihe na - eme ka akụrụngwa Lius dị elu ma belata ihe egwu nke lithium ,ụbiga mmanya ókè, yabụ, anaghị atụ aro iji otu oge,

Ndị NSAID, gụnyere nhọrọ ndị na-egbochi COX-2 - na ụfọdụ ndị ọrịa, ojiji nke NSAIDs, gụnyere Ndị na-egbochi COX-2, nwere ike belata akwara, natriuretic na mmetụta antihypertensive nke diuretics.

Mmetụta na nsonaazụ ụlọ nyocha - N'ihi nsonaazụ calcium, thiazides nwere ike imetụta nsonaazụ nyocha ọrụ parathyroid.

Usoro onunu ogwu na nhazi

N'ime n'agbanyeghị nri.

Ihe mbụ a na-eme na ntinye bụ 1 mbadamba. kwa ụbọchị. Maka ndị ọrịa ahụ enweghị ike ịnweta nchịkwa ọbara mgbali zuru oke na usoro a, enwere ike ịbawanye dose ahụ gaa mbadamba abụọ. (50 mg / 12.5 mg) ma ọ bụ mbadamba 1. (100 mg / 25 mg) 1 oge kwa ụbọchị. Ogo kachasị nari bụ mbadamba abụọ. (50 mg / 12.5 mg) ma ọ bụ mbadamba 1. (100 mg / 25 mg) 1 oge kwa ụbọchị.

Na mkpokọta, enwere mmetụta hypotensive kacha mma n'ime izu 3 mgbe mmalite ọgwụgwọ.

Enweghị mkpa maka nhọpụta mbụ maka ndị ọrịa agadi.

Ntụziaka pụrụ iche

Enwere ike ido ya ya na ọgwụ ndị ọzọ na - alụ ọgụ.

Enweghị mkpa maka nhọpụta mbụ pụrụ iche maka ndị ọrịa agadi.

Ọgwụ nwere ike ime ka ịta ụta nke urea na creatinine na plasma ọbara na ndị ọrịa nwere akwara akwara Stenosis ma ọ bụ akụrụ akwara nke otu akụrụ.

Hydrochlorothiazide nwere ike ime ka hypotension artpot na mmiri ghara ịba uru nke mmiri (electrolyte) na-abawanye (mbelata na BCC, hyponatremia, hypochloremic alkalosis, hypomagnesemia, hypokalemia), iguzogide nnabata glucose, belata urinary calcium excretion ma mee ka mgbatị ahụ dị ntakịrị, mmụba dị elu na cholestrol ọbara. na triglycerides, kpasuo omume nke hyperuricemia na / ma ọ bụ gout.

Remata ọgwụ na-arụ ọrụ na usoro renin-angiotensin n'oge oge nke II na III nke afọ ime nwere ike ibute ọnwụ nke nwa ebu n'afọ. Ọ bụrụ na afọ ime, a na-egosi iwepụ ọgwụ.

Enweghị ihe omuma banyere nsonaazụ na ikike ịkwọ ụgbọala na usoro ndị ọzọ.

Ihe ngosi maka ojiji

Edere ọgwụ ahụ maka ndị ọrịa nwere nsogbu dị iche iche:

1. Ọbara ọbara. E gosipụtara ọgwụ a maka ndị ọrịa nwere ọbara mgbali elu. Mgbe ị na-a theụ ọgwụ "Vazotens" ọ dị mkpa iji nyochaa ndị na - egosi ọbara mgbali mgbe niile.
2. Ọrịa obi na-adịghị ala ala. N'iburu ogbaaghara nke udiri oria a, obi agha na-ebelata n’etiti ndi obia. Ọtụtụ mgbe, ndị agadi na-arịa ọrịa ahụ.

E debere ọgwụ a "Vazotens" yana ọgwụ ndị ọzọ. A nabatara ọgwụ ahụ nke ọma ka ọ na-ewere ndị na - egbochi ACE. Dọkịta ga-eburu n'uche usoro ọgwụgwọ na njirimara nke anụ ahụ.

Edere ọgwụ ahụ maka nkụchi obi

Etu ị ga - esi mee ya, oleekwa ụdị usoro onunu ogwu a

Edere "Vazotens" nye ndị ọrịa nwere ọbara mgbali elu. A na -e oara ọgwụ ahụ ọnụ, n'agbanyeghị nri. Ikwesiri ị tabletsụ mbadamba 1 oge kwa ụbọchị.

Ọ bụrụ na a chọpụtala na ndị ọrịa nwere ọbara mgbali elu, ọgwụgwọ ahụ na-amalite site na obere usoro. Edere onye ọrịa ọgwụ 50 mg nke losartan. Ọ bụrụ na ọ dị mkpa yana dịka akaebe dọkịta si kwuo, enwere ike ịbawanye ọgwụ ahụ gaa na 100 mg. Mgbe ahụ a na-ekewa ọnụọgụ ahụ gaa usoro abụọ - n'ụtụtụ na mgbede.

Ndị nwere nkụchi obi kwesịrị iwepụta ọgwụgwọ ntakịrị. Ọgwụ mbụ bụ 12.5 mg otu ugboro kwa ụbọchị. Ọ bụrụ na onye ọrịa ahụ anabata ọgwụgwọ ahụ nke ọma, ka ụbọchị 7-10 gachara usoro ịba ụba ga-abawanye.

Ọgwụ Farmacology

Ọgwụ Vazotens na-ezo aka na ọgwụ antihypertensive - ndị na - ebuso ya agha nke angiotensin nke 2. Ọ naghị ebelata enzyme kinase, nke na - emebi bradykinin. Ọgwụ nwere mmetụta diuretic, anaghị emetụta ọdịnaya nke adrenaline, aldosterone na plasma.

N'ihi omume nke ọgwụ ahụ, hypertrophy nke akwara myocardial adịghị etolite, nnabata maka ọrụ anụ ahụ na-abawanye na nkụda obi. Mgbe otu mbadamba mbadamba mbadamba, nsogbu ahụ na-ebelata, nsonaazụ ahụ ruru ogo ya ka ọ gachara awa 6 wee ruo ụbọchị. A na-egosipụta ịdị irè nke ọgwụ ahụ na izu 3-6 nke ọgwụgwọ. Site na imeju imeju, itinye uche nke ihe na - arụ ọrụ na - abawanye, yabụ achọrọ ndozi dose.

Losartan na-etinye obi gị dum na afọ, nwere bioavailability nke 33%. Ihe ahụ na-erute ịta kachasị mgbe elekere gachara, metabolite nọ n'ọrụ - mgbe awa 3-4 gachara. Ndụ ọkara nke losartan bụ awa 1.5-2, metabolite bụ awa 6-9. Otu ụzọ n'ụzọ atọ nke ọgwụ a na-apụ apụ na mmamịrị, nke ọzọ nwere ọnya.

Ihe mejupụtara nke Vazotenza N na-agụnye diuretic hydrochlorothiazide, nke na-ezo aka n'ụdị ụdị thiazide. Ọ na - ebelata reabsorption nke sodium ion, na - eme ka akụkụ mmamịrị pụta, bicarbonate. Site na ibelata olu ọbara na-erugharị, mgbali na-ebelata, nrụghachi nke akwara vaskụla na-agbanwe, mmetụta nke vasoconstrictors na-ebelata, mmetụta nkụda mmụọ na ganglia na-abawanye.

Usoro onunu ogwu na nhazi

A na-ewere mbadamba Vazotens otu ugboro n'ụbọchị. Site na ọbara mgbali elu, kwa ụbọchị bụ 50 mg, mgbe ụfọdụ ọ na-abawanye ka 100 mg na 1-2 doses. N’ewepu obi, usoro izizi bụ 12.5 mg otu ugboro n’ụbọchị. A na-abawanye ọgwụ ahụ kwa izu site na 12.5 mg iji ruo 50 mg otu ugboro kwa ụbọchị. Site na nchịkwa oge nke diuretics, a na-ebelata usoro izizi ruo 25 mg kwa ụbọchị.

N'ihe banyere ọrụ imeju na - arụ ọrụ (ịbelata ihe njikwa creatinine), usoro ịbelata na-ebelata, na nká, na ọrịa akụrụ na-emecha, na -emezi ya. Mmetụta kasịnụ na-apụta mgbe izu 3 gachara. N'ime akwukwo nri, adighi eji ogwu a. Ntụziaka pụrụ iche maka ojiji a si na ntuziaka:

1. Tupu ịkọwa ọgwụ, a na-eme mgbazi akpịrị ịkpọ nkụ, ma ọ bụ na ịchọrọ iji ọgwụ ahụ na ọgwụ dị ala.
2. Ngwá ọrụ nwere ike ime ka ịta ụba urea dị n'ọbara site na akụrụ renal stenosis.
3. N'oge usoro ọgwụgwọ, ọ dị mkpa ijikwa ọkwa nke potassium n'ime ọbara, karịsịa na ndị agadi, ebe ọ bụ na ndị ọrịa dị otú ahụ nwere oke ihe ize ndụ nke ịmalite hyperkalemia (ịba ụba ọkwa nke potassium na plasma ọbara).
4. Iji ọgwụ n'oge ịtụrụ ime nwere ike ime ka mmadụ nwee ntụpọ ma ọ bụ ọnwụ nwa ebu n'afọ. Site na iji oliko, a machibidoro iji vasotens aka.

Usoro ire na ebe nchekwa

Vazotens na-ezo aka na ọgwụ ndenye ọgwụ, echekwara na ọnọdụ okpomọkụ ruo ogo 30 ruo ihe karịrị afọ 2, na ụmụaka agaghị eru.

Ndị na-ahụ maka ọgwụ na-egbu egbu nwere ihe dị iche nwere ike dochie ọgwụ. Ihe analogs Vazotens:

• Lorista - mbadamba sitere na losartan,
• Lozap bụ nkwadebe mbadamba ụrọ nke nwere losartan dị ka ihe na-arụ ọrụ.

International Nonproprietary Aha

INN nke ọgwụ bụ losartan.

A na-enyekarị ndị ọrịa Vasotens ọgwụ maka ndị na-arịa ọbara mgbali elu.

Na nhazi ọkwa mba ATX, ọgwụ a nwere koodu C09CA01.

Weputara udi ya na ihe mebere ya

Ihe kachasị dị n'ọrụ Vazotens bụ potassium losartan. Ngwa mgbakwunye ọgwụ a gụnyere sodium croscarmellose, mannitol, hypromellose, magnesium stearate, talc, propylene glycol, wdg. Nhazi nke Vazotenza N, na mgbakwunye na losartan, gụnyere hydrochlorothiazide.

Vasotens dị n'ụdị mbadamba ụrọ nwere ọgwụ ọnụọgụ 25, 50 na 100 mg. All mbadamba nkume ndị ahụ na-agba gburugburu. Ejiri mkpuchi ọcha kpuchie ha ma edepụtara ha "2L", "3L" ma ọ bụ "4L" dabere na usoro onunu ogwu. A kwakọtara ha na blisters nke 7 ma ọ bụ 10 PC. N’ime kaadiboodu enwere blister 1, 2, 3 ma ọ bụ 4 na mpempe akwụkwọ nwere ozi gbasara ọgwụ.

Vasotens dị n'ụdị mbadamba ụrọ nwere ọgwụ ọnụọgụ 25, 50 na 100 mg.

Omume ọgwụ

Ngwongwo nke ogwu nke ogwu ahu bu n'ihi akuko a na-aru aru nke Vazotenz, ihe akari ji eme ihe bu ihe nnabata antagonensin nke 2. Site na ọgwụgwọ vasotenz, ihe na-arụ ọrụ nke ọgwụ ahụ na-enyere aka belata OPSS. Ọgwụ na-ebelata itinye uche nke aldosterone na adrenaline na plasma ọbara. Ọgwụ a nwere mmetụta ejikọtara ọnụ, na-enye aka na nrụgide nke ịdị na ahụ ike na mgbasa akwara.

Na mgbakwunye, ọgwụ na-arụ ọrụ nke ọgwụ ahụ na-ebelata ibu dị na sistem obi ma na-enwe mmetụta diuretic. N'ihi mmetụta dị mgbagwoju anya, ọgwụgwọ na vasotens na-ebelata ihe ize ndụ nke ọbara mgbali myocardial. Ọgwụ a na - enyere aka ịbawanye nnabata mmega ahụ na ndị ọrịa nwere nnukwu ihe ịrịba ama nke nkụda obi.

Ọgwụ anaghị egbochi nchịkọta nke ụdị 2 kinase. Enzyme a nwere mmetụta na-emebi emebi na bradykinin. Mgbe ị na-a medicationụ ọgwụ a, a na-ahụ mbelata ọbara mgbali elu ka awa 6 gachara. N’ọdịnihu, ọrụ nke ọgwụ ike n’ọrụ jiri nwayọ belata awa iri abụọ na anọ. N'iji usoro eji eme ihe, a na-ahụkarị nsonaazụ kachasị mgbe izu 3-6 gasịrị. N'ihi ya, ọgwụ a chọrọ ogologo oge iji eme ihe.

Jiri nlezianya

Ọ bụrụ na onye ọrịa ahụ nwere akara nke arụ ọrụ akụrụ yana arụ ọrụ akụrụ, ịgwọ ọrịa Vazotens chọrọ nlebara anya pụrụ iche nke dọkịta. Na mgbakwunye, nlekọta pụrụ iche chọrọ ojiji nke vazotens na ọgwụgwọ ndị mmadụ na-arịa ọrịa Shenlein Genoch. Na nke a, achọrọ ịgbanye ọgwụ mgbe niile iji belata ihe egwu ịmalite ịrịa oke nsogbu.

Etu esi ewere vasotens?

Emere ọgwụ a maka nchịkwa ọnụ. Iji nweta ọgwụgwọ ọgwụgwọ, onye ọrịa ahụ kwesịrị ị doseụ ọgwụ enyere ya oge 1 n'ụtụtụ. Iri nri anaghị emetụta nnabata nke ọgwụ. Iji mee ka ọbara dị mma ma kwalite ya na ọkwa nkịtị, a na-egosi ndị ọrịa na-a Vaụ ọgwụ Vazotenza na 50 mg kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, enwere ike ịbawanye ọgwụ ahụ ruo 100 mg kwa ụbọchị.

Ọ bụrụ na onye ọrịa ahụ nwere ihe ịrịba ama nke obi nkụchi, a na-atụ aro ịrị elu nke nwayọ na vasotenz. Nke izizi, a na-enye onye ọrịa ọgwụ ka ọ 12ụọ ọgwụ 12.5 mg kwa ụbọchị. Mgbe ihe dị ka otu izu gasịrị, ọgwụ ahụ na-abawanye ruo 25 mg. Mgbe ụbọchị asaa ọzọ nke ị theụ ọgwụ ahụ, ọgwụ ya na-eto 50 mg kwa ụbọchị.

Ọ bụrụ na onye ọrịa ahụ nwere ihe ịrịba ama nke nsị nsị imeju, ọgwụgwọ na Vazotens chọrọ nlekọta pụrụ iche nke dọkịta.

Sistemụ akwara Central

Ihe dị ka 1% nke ndị ọrịa na-anara ọgwụgwọ vasotens nwere mgbaàmà asthenia, isi ọwụwa, na anya mmiri. Ọgba aghara ụra, ihi ụra ụtụtụ, ike ọgwụgwụ mmetụta uche, ihe ịrịba ama nke ataxia na akụkụ neuropathy n'ọnọdụ ndị dị ụkọ nwere ike ịda n'oge ọgwụgwọ vasotenz. Mmetụta uto nwere ike imebi ya na mmehi anya. Na mgbakwunye, enwere ihe ọghọm nke uche aka na ụkwụ.

Site na usoro mkpụrụ ndụ ihe nketa

Vnwere vasotenza nwere ike ịmepụta ọnọdụ maka mmepe nke ọrịa na - efe efe nke ọnya afọ. N'ọnọdụ ndị a na-adịghị ahụkebe, ndị ọrịa nwere mkpesa nke urination ugboro ugboro yana arụ ọrụ ezumike arụ ọrụ. N'ime ụmụ nwoke, site na ọgwụgwọ vasotenz, mbelata libido na mmepe nke enweghi ike.

Ikekwe, ọdịdị nke akpụkpọ anụ akọrọ.

Si na akuko obi

Site na usoro ọgwụgwọ vasotenz ruo ogologo oge, onye ọrịa ahụ nwere ike ịmalite hypotension orthostatic. Mwakpo Angina na tachycardia kwere omume. N'ọnọdụ ndị na-adịghị ahụkebe, ị theụ ọgwụ na-akpata ọbara ọgbụgba.

Ọtụtụ mgbe, ojiji nke vasotenz na-akpata mmeghachi ahụ nfụkasị dị nro, nke a na-egosipụta site na itching, urticaria, ma ọ bụ ọnya ọnya. Oge ụfọdụ, ịhụbe mmepe nke ọrịa angioedema.

Jiri n'oge ime na lactation

Emebeghị ka amata ọfụma na nchekwa nke iji vasotenza n'oge afọ ime. N'okwu a, enwere ihe akaebe nke mmetụta ọjọọ nke ọgwụ ọjọọ na - enye nwa ebu n'afọ n’ime oge nke abụọ na nke atọ nke afọ ime. Nke a na-abawanye n'ihe ize ndụ nwatakịrị na-etolite etuto ọjọọ na ọnwụ intrauterine. Ọ bụrụ na ọgwụgwọ dị mkpa, a ga-atụ aro ịhapụ inye ara.

Site na usoro ọgwụgwọ vasotenz ruo ogologo oge, onye ọrịa ahụ nwere ike ịmalite hypotension orthostatic.

Ọnụ ego maka vasotens

Ọnụ ego nke ọgwụ ahụ na ụlọ ahịa ọgwụ sitere na 115 ruo 300 rubles, dabere na usoro onunu ogwu.

Otu n'ime ama analogues nke ama ama nke ogwu bu Lozap.
Cozaar bụ analogue nke ọgwụ Vazotens.
Otu ọgwụ ọzọ bụ Presartan.
Ihe analog nke ọgwụ Vazotens bụ Lorista.Lozarel bụ otu n'ime ọgwụ ndị ama ama nke ọgwụ Vazotens.

Ndi Okacha Cardio

Grigory, 38 afọ, Moscow

N'ebe m na-arụ ọrụ ọgwụ, ana m atụkarị ojiji nke vazotens maka ndị ọrịa na-arịa ọbara mgbali elu. N'ihi mgbakwunye hypotensive na mmetụta diuretic, ọgwụ ọ bụghị naanị na-enye aka ịme ka ọbara mgbali elu dịkwuo mma, kama ọ na-emekwa ka ndidi na-anabata ndidi na mmega ahụ ma belata ogo edema. A na-anabata ọgwụ ahụ nke ọma n'agbanyeghị ndị ọrịa agadi. Na mgbakwunye, o kwesịrị ekwesị maka itinye na usoro ọgwụgwọ dị mgbagwoju anya site na iji ọgwụ antihypertensive ọzọ.

Irina, 42 afọ, Rostov-on-Don.

Anọwo m na-arụ ọrụ dị ka ọkachamara n'ọrịa obi ruo ihe karịrị afọ 15, ndị ọrịa na-anagide mkpesa nke ọbara mgbali elu na-agakarị Vazotens. Mmetụta nke ọgwụ a n'ọtụtụ oge zuru ezu iji nọgide na-enwe nrụgide nkịtị na-enweghị mkpa iji mgbakwunye. Ndị ọrịa a anabatala ọgwụ a nke ọma, ọ naghị enwekarị ike ịkpata nsonaazụ. N'ihi nke a, ị nwere ike iji ya rụọ ọrụ nke ọma na usoro ọmụmụ ogologo.

Igor, gbara afọ 45, Orenburg

Ọtụtụ mgbe ana m akwado iji vasotenza mee ihe maka ndị ọrịa na-arịa ọrịa obi. Ọgwụ na-enyere gị aka nwayọ nwayọ nwayọ ọbara ma belata ogo edema nke ala ala. Ngwá ọrụ na-aga nke ọma na ọgwụ ndị ọzọ ejiri mee ihe na ọgwụgwọ nke ọrịa a. N'ime ọtụtụ afọ m na-eme, ahụtụbeghị m ọdịdị nke mmetụta ndị ọrịa na-eji vazotens.

Mgbe ị na-eji ọgwụ ahụ, a ghaghị ilezi anya iji jikwaa usoro ndị dị mgbagwoju anya.

Margarita, gbara afọ 48, Kamensk-Shakhtinsky

Amatala m nsogbu nke ọbara mgbali elu karịa afọ 15. Na mbido, ndị dọkịta tụrụ aro ka belata ibu, na-agagharị mgbe niile na ikuku dị mma ma na-eri nri nke ọma, mana nsogbu a bịara kawanye njọ. Mgbe nrụgide ahụ kwụgidere na 170/110, ndị dọkịta malitere ịkọpụta ọgwụ. Afọ atọ gara aga ejirila m Vazotens gwọọ m. Ngwá ọrụ na-enye ezigbo nsonaazụ. Ana m ewere ya n'ụtụtụ. Nrụgide ahụ akwụsịla. Ọzịza nke ụkwụ kwụsịrị. Ọ malitere inwe ọ cheụ karịa. Enyerela akwa mgbago elu ugbu a na-enweghị ume iku ume.

Andrey, 52 afọ, Chelyabinsk

Ọ medicationsụrụ ọgwụ dị iche iche maka nrụgide. Ruo ihe dị ka otu afọ, ọkà mmụta banyere akwara banyere iji ọgwụ vazotens eme ihe. Ngwá ọrụ na-enye ezigbo nsonaazụ. Ikwesiri iwe ya naanị otu oge kwa ụbọchị. Nrụgide alọghachiri n'ọnọdụ nkịtị ka izu abụọ ebiri. Ugbu a, ana m a thisụ ọgwụ a kwa ụbọchị. Ahụghị m mmetụta ọ bụla.