Kedu ihe dara nke methyl ethyl pyridinol maka?
Ọkpụkpụ ahụ doro anya, enweghị agba ma ọ bụ acha odo odo.
1 ml | |
methylethylpyridinol hydrochloride | 10 mg |
Ndị pụrụ iche: hydrochloric acid 0.1 M ngwọta - ruo pH 2.5-3.5, mmiri d / i - ruo 1 ml.
1 ml - iko ampoules (5) - ngwugwu ọnya (1) - ngwugwu nke kaadiboodu.
1 ml - iko ampoules (5) - ngwugwu ọnya (2) - ngwugwu nke kaadiboodu.
1 ml - iko ampoules (5) - ngwugwu nke kaadiboodu.
1 ml - iko ampoules (10) - ngwugwu nke kaadiboodu.
Omume ọgwụ
Angioprotector, na-ebelata ikike nke vaskụla vaskụla, bụ ihe na - egbochi usoro mgbochi, freehypoxant na antioxidant.
Na-ebelata viscosity ọbara na nchịkọta platelet, na-abawanye ọdịnaya nke cyclic nucleotides (cAMP na cGMP) na platelet na akwara ụbụrụ, nwere ọrụ fibrinolytic, na-ebelata ike nke mgbidi vaskụla na ihe ize ndụ nke ọbara ọgbụgba, na-akwalite resorption ha. Na-agbasa arịa ọbara ọgbụgba, n'oge nnukwu oge nke myocardial infarction na-egbochi ogo nke necrosis, na-eme ka mmekọrịta dị mma nke obi yana ọrụ ya. Increasedba ụba ọbara mgbali nwere mmetụta hypotensive. Na nnukwu nsogbu ischemic nke mgbasa akwara na-ebelata ogo mgbaàmà ọrịa ụbụrụ, na-eme ka iguzogide anụ ahụ na hypoxia na ischemia.
Ọ nwere njiri amamịghe, na-echekwa njigide retina na mmetụta mbibi nke ọkụ dị elu, na-akwalite resorption nke intraocular hemorrhages, na-eme ka microcirculation anya dịkwuo mma.
Ngosiputa ogwu
Dị ka akụkụ nke usoro ọgwụgwọ dị mgbagwoju anya: nsonaazụ nke ọghọm ụbụrụ nke ọrịa ischemic na ọdịdị ọbara, isi ọwụwa, oge epi- na hematomas subdural, nnukwu myocardial infarction, mgbochi nke reperfusion syndrome, angina pectoris na-ejighị n'aka.
Ọkpụkpụ Subconjunctival na intraocular, angioretinopathy (gụnyere ọrịa shuga), chorioretinal dystrophy (gụnyere atherosclerotic sitere), dystrophic keratitis, thrombosis retinal, nsogbu nke myopia, nchebe nke cornea (mgbe ị na-ele anya kọntaktị) na retina nke anya ọkụ dị elu (laser na anwụ, na laser-coagulation), trauma, ọnya na ọkụ nke cornea, cataract (gụnyere mgbochi n'ime ndị mmadụ karịrị 40), ịwa ahụ anya, ọnọdụ mgbe ọwachara ahụ maka r laucoma na chocho detachment.
Koodu ICD-10Koodu ICD-10 | Ngosipụta |
F07 | Alitydị mmadụ na nsogbu omume n'ihi ọrịa, mmebi, ma ọ bụ ụbụrụ ụbụrụ |
F07.2 | Ọrịa post-contusion |
H20.2 | Lens iridocyclitis |
H21.0 | Hyphema |
H31.1 | Choroidal degeneration |
H31.2 | Ihe nketa dystrophy nke choroid |
H34 | Ntughachi Vaskụla nwa nwa |
H35.6 | Ọbara azụ |
H36.0 | Ọrịa mamịrị retinopathy |
H52.1 | Myopia |
I20.0 | Angina na-ejighi |
I21 | Nnukwu myocardial infarction |
I61 | Ọbara ọbara intracerebral (ụdị ọria ụbara nke ụbara) |
I63 | Ngwunye ụbụrụ |
I69 | Nsonaazụ nke ọrịa ụbụrụ |
T26 | Igwe na-ere ọkụ na kemịkalụ kemịkal na-ejedebeghị na anya na adnexa |
Usoro usoro onunu ogwu
Na neurology na cardiology - iv drip (20-40 tụlee / min), 20-30 ml nke ihe 3% (600-900 mg) 1-3 ugboro n'ụbọchị maka ụbọchị 5-15 (na mbụ ọgwụ a gwakọtara ya na 200 ml nke 0.9% ihe ndozi NaCl ma ọ bụ 5% dextrose solution). Ogologo oge ọgwụgwọ a na-adabere n'ọrịa ahụ. Na-esote, ha na-agbanye na nchịkwa intramuscular - 3-5 ml nke 3% ngwọta 2-3 ugboro n'ụbọchị maka ụbọchị 10-30.
Na ophthalmology - subconjunctival ma ọ bụ parabulbar, oge 1 kwa ụbọchị ma ọ bụ ụbọchị ọ bụla. Subconjunctival - 0.2-0.5 ml nke 1% ngwọta (2-5 mg), parabulbar - 0,5-1 ml nke 1% ngwọta (5-1 mg). Ogologo oge ọgwụgwọ bụ ụbọchị 10-30, ọ ga-ekwe omume ịmegharịa usoro ahụ ugboro abụọ n'afọ.
Ọ bụrụ na ọ dị mkpa, retrobulbar na 0,5-1 ml nke 1% ngwọta 1 oge kwa ụbọchị maka ụbọchị 10-15.
Iji kpuchido retina n'oge coagulation laser (gụnyere mgbochi na mgbochi coagulation nke etuto ahụ) - parabulbar ma ọ bụ retrobulbar 0,5-1 ml nke 1% awa 24 na elekere 1 tupu coagulation, mgbe ahụ na otu doses (0,5 ml ọ bụla) 1% ngwọta) 1 oge kwa ụbọchị maka ụbọchị 2-10.
Aha ahia
Na netwọ nkesa, ana-akpọ anya mmiri Emoxipin, ya na methylethylpyridinol (methylethylpiridinol) bụ isi ihe na-arụ ọrụ. Ntinye uche ya na ngwọta bụ 1%, i.e., 1 ml nke ọgwụ nwere 10 mg nke isi ihe.
Mbepu anya dị na rọba, kwadebere mpe mpe mpe, karama ndị jupụtara na mmiri doro anya, na-enweghị ụcha. Olu nke ọ bụla bụ 5 ml ma ọ bụ 10 ml. A na-etinye karama ahụ na igbe kaadiodu na ntuziaka ndị akọwapụtara.
Ihe analog nke usoro ndia bu Emoxy-Optic.
Methylethylpyridinol dịkwa na 1 ml ampoules. A na-ejikwa ụdị ọgwụ a iji gwọọ ọrịa anya ma enwere ike ịchịkwa subcutaneously (ala nke anya) ma ọ bụ na-abanye na anya (obere ọkara nku anya). A na-eji ụzọ ndị a ọgwụ nchịkwa na laser coagulation.
Dịka ntuziaka ahụ si dị, enwere ike idobe anya mmiri Emoxipin na t agaghị elu karịa + 25 Celsius C maka afọ 2, na mgbe ịmepe ya - ihe gafere ụbọchị iri atọ. Ekwesịrị ịchekwa ebe nchekwa ahụ site na ìhè anyanwụ kpọmkwem na ebe ụmụaka agaghị erute.
Ntuziaka maka ojiji: egosi na contraindications
A na-eji Emoksipin anya anya na-agwọ ọrịa dịgasị iche iche, ojiji ha dịkwa maka prophylactic nzube:
- Angiopathy na-arịa ọrịa shuga - nsogbu nke pathology na ogologo ọrịa, kwupụtara ọnya ọbara arịa,
- Glaucoma - enwere nkwarụ anya na - enwe nsogbu site n'oge ruo n'oge
- Myopia - myopia, mgbe ụzarị ọkụ na-abanye n’ilekwasị anya n'otu ebe na-erute na retina. N’ihi nke a, mmadụ anaghị amata ihe dị iche iche dị anya,
- Hypermetropia - farsightedness, nke ozo myopia. Onye ọrịa na-ahụ nke ọma na anya, ihe dị nso na-enyocha.
- Ọ na-agba anya - mmebi nke ihe dị na mpụta n'ihi nsị kemịkal, elu t, ultraviolet radies, vapors.
Gụkwuo gbasara ọrịa glaucoma ebe a.
Methylethylpyridinol bụ ihe dị irè na ọgwụgwọ nke usoro mkpali na azụ anụ ahụ nke mpụga, na-enwe ọbara ọgbụgba mgbe ọ gasịrị, yana nsogbu nke conjunctivitis.
Standardkpụrụ usoro eji arụ ọrụ gụnyere instillation na anya ọ bụla 1 dobe ugboro 2-3 kwa ụbọchị. Oge nkezi nke ọgwụgwọ bụ ụbọchị 3-10. Agbanyeghị, dị ka dọkịta si kwuo, enwere ike ịgbatị akwụkwọ ahụ ruo ọnwa 1. A na - enweta usoro ọgwụgwọ dị mma site n'idebe iwu ole na ole dị mfe:
- Jiri ncha sachaa aka gi nile tupu usoro a,
- Tupu iji igwe eji atụpu ihe, lelee iji hụ ma enwere enwere nkụ ọ bụla na njedebe nke nwere ike imerụ anya,
- Mgbe ị na-etinye, emetụla nkụ ahụ aka n'anya,
- Mgbe usoro a gachara, mechie nku anya, ma wepu mmiri ọ bụla ejirila akwa na - adịghị mma,
- Wepu oghere kọntaktị tupu instillation na 15 nkeji. , ma jiri ejiji gafee nkeji iri na ise. mgbe usoro a gasịrị.
Nwere ike gụọ ederede maka ilele anya ebe a.
N'oge ọgwụgwọ, ọhụụ nwere ike ịmịcha, yabụ, ndị na-eme ihe omume chọrọ nlebara anya kwesịrị iwere izu.
Ihe ngbanwe
Ndepụta contraindications maka Emoxipin nwere obere ihe, yana ihe niile metụtara mmachibido iwu ndị a na-enwe ugbu a n'ihe fọrọ nke nta ka ọ bụrụ ọgwụ ọ bụla.
Amachibidoro iji anya nke methylethylpyridinol na ọnụnọ nke ọnọdụ ndị a ka amachibidoro:
- Hypersensitivity na ihe nọ n'ọrụ na ihe ndị ọzọ,
- Afọ ndidi agaghị agafe afọ 18
- Oge ịmụ nwa na inye nwa ya nri.
Ekwesịrị ilebara anya na ndị ọrịa nwere ebumnuche mmeghachi omume nfụkasị, ọkachasị na mmalite ọgwụgwọ. Ọ bụrụ na enwere ahụ erighi ala nke na-anaghị apụ apụ n'ọtụtụ usoro, ekwesịrị ịkwụsị ma gwọọ ọgwụgwọ ọzọ.
N’oge ime ime
Oge mmemme (oge mmebi) - otu n’ime ọrụ kachasị na ndụ nwanyị ọ bụla. Ọgwụ ọ bụla bụ ihe a na-achọghị n'oge afọ ime, n'ihi na enwere obere ihe ọghọm nke itinye ezigbo mmetụta na nwa ebu n'afọ. Substancesfọdụ ihe ụfọdụ nwere ike ịbanye na Plasenta.
N'ezie, mgbe ị na-eji anya mmiri, mmịkọta usoro na-adịkarị ntakịrị. Agbanyeghị, methyl ethyl pyridinol bụ ihe siri ike nke na-emetụta ọtụtụ usoro metabolic na ahụ.
Mmachibido iwu nke iji ọgwụ a dabere na enweghị data a pụrụ ịdabere na ya na nsonaazụ nke ojiji a, ebe ọ bụ na, na ndammana, a dịghị eme ụmụ nwanyị dị ime nyocha. Yabụ, ebe ọgwụ a bụ ọgwụ, ọgwụ a ga-enye ya bụ ọgwụgwọ dọkịta.
Nkọghachi azụ nke ọkpụkpụ azụ - ọgwụgwọ na ọgwụgwọ ndị mmadụ na ọgwụ a kọwara n'isiokwu a.
Littlemụaka
Banyere ọgwụgwọ ụmụaka, ntụziaka ahụ na-egbochi afọ ole ka ọ bụrụ afọ 18 - tupu nke a, a naghị atụ aro ka ụmụaka mesoo ụmụaka. Agbanyeghị, ụfọdụ ndị na-emepụta ka na-ekwu maka eziokwu ahụ bụ na mmachi a dabakwara na enweghị nsonaazụ ndị a pụrụ ịdabere na ya banyere iji ọgwụ ahụ.
Gụkwuo banyere anya mmiri Dexamethasone na njikọ ahụ.
Na omume, ndị na-ahụ maka ụmụaka na-ekwukarị Emoxipine ọbụlagodi ụmụ amụrụ ọhụrụ, ebe ọ bụ na ọgwụ ụmụaka dị irè maka ọrịa anya ụfọdụ adịghị adị.
Nsogbu enwere ike idi na ogwu a
Nyocha ndị ọrịa na-egosi na a na-anabata ọgwụ ahụ n'ozuzu ha. N'ọnọdụ ndị a na-adịghị ahụkebe, mmetụ ahụ erughị ala n'ụdị mmeghachi omume nfụkasị: enwere ike: ọkụ, itching, redness, lacrimation.
N'ihe banyere iji njikọta ọgwụ na ọgwụ ndị ọzọ, a na-atụ aro ka iji Methylethylpyridinol ikpeazụ, ka ọ dịkarịa ala minit 15. mgbe itinyechara ọgwụ ikpeazụ.
Ihe dị ka ọdịda maka anya Tsiprolet ka edere n’edemede ahụ.
Dika analogues nke ogwu, Emoxy-optic, Emoxipin-AKOS, Emoxibel nwere ike iji ya.
Ọgwụ a bụ ọgwụ dị oke oke nke nwere ike imetụta ọtụtụ usoro metabolic na anụ ahụ anya. Yabụ, iji ya maka ọgwụgwọ na ebumnuche prophylactic nwere ike izi ezi n'ihu ọnụọgụ ọrịa, yana ihe egwu dị na mmepe ha.
N'agbanyeghị eziokwu ahụ bụ na ọgwụ ahụ bụ ụzọ ekpughere ọhaneze, ojiji a ga-agu n'onye ezi omume ma rụọ ya naanị n'okpuru nlekọta nke dibia anya.
Guo kwa ihe banyere ogwu dika ciprofloxacin na-eme ihe a.
Mwepụta wepụtara ya na ihe mebere
Sdị usoro onunu ogwu - injection: mmiri dị ọcha, nke na-enweghị odo ma ọ bụ nke edo edo, 1 ml nke ọ bụla n’ime ampoules nke nọchiri anya iko ma ọ bụ iko nwere klaasị hydrolysis nke HGA1, na otu kaadiboodu nke 5 ma ọ bụ 10 ampoules zuru oke na ampoule scarifier (mgbe ị na-ebu ampoules etinyeghị ihe ndị ahụ na - adịghị etinye mgbanaka ma ọ bụ nke mgbawa) ma ọ bụ ngwugwu 1-2 nke 5 ampoules na ntuziaka maka iji Methylethylpyridinol, nkwakọ ngwaahịa maka ụlọ ọgwụ - na ngwungwu kaadi anọ nke 4, 5, 10, 50 ma ọ bụ 100 ngwongwo contour cell. 5 vials.
Ngwakọta nke 1 ml nke ihe ngwọta:
- ihe na-arụ ọrụ: methylethylpyridinol (n'ụdị hydrochloride) - 10 mg,
- ihe inyeaka: 0.1 M hydrochloric acid solution, mmiri maka ịgba ntụtụ.
Mlọ ọgwụ
Methylethylpyridinol bụ ọgwụ antioxidant, na-egbochi usoro ntụgharị n'efu.
Ọ nwere mmetụta bara uru na sistemu ọbara ọbara: ọ na-ebelata viscosity ọbara, mee ka oge coagulation dị ogologo, ma gbochie nchịkọta nke platelet. Ọ na - eme ka akpụkpọ anụ ọbara ọbara na sel ọbara arịa dịkwuo ike, na - eme ka iguzogide mkpụrụ ndụ ọbara uhie na hemolysis na trauma n'ibu.
Ọ na-abawanye ọdịnaya nke cyclic nucleotides na platelet (cyclic adenosine monophosphate na cyclic guanosine monophosphate), na-ebelata ikike nke mgbidi vaskụla, na-akwalite ndozi nke ọbara ọgbụgba, ma nwee ọrụ fibrinolytic.
Ọ na - eme ka microcirculation dị na anụ ahụ nke anya, tinyere arịa retina. Ọ nwere mmetụta retinoprotective, na-echebe retina na mmetụta mmebi nke ọkụ dị oke.
Ihe ngosi maka ojiji
Ejiri Methylethylpyridinol dị ka akụkụ nke usoro ọgwụgwọ siri ike maka ọrịa / ọnọdụ ndị a:
- dystrophic ọrịa nke cornea,
- ọbara mgbochi intraocular na subconjunctival nke usoro dị iche iche,
- Central diorophy nke di na etiti,
- angioretinopathy (gụnyere ọrịa shuga),
- ajọ ihe (angnessclerotic macular degeneration (akọrọ akọrọ),
- thrombosis nke isi akwara nke retina na alaka ya,
- nsogbu nke myopia,
- Ugo nke abuo gbara oku na mmeru aru,
- Mkpochi choroid na oge izizi nke glaucoma,
- mmebi anya na ọkụ dị elu (radieshon laser n'oge ịgwakọta laser) - ọgwụgwọ na mgbochi.
Methylethylpyridinol, ntuziaka maka ojiji: usoro na usoro onunu ogwu
A na-edozi ọgwụ mgbochi Methylethylpyridinol parabulbarno (s / b) ma ọ bụ subconjunctival (s / c). A na-eji ọgwụ ahụ eme ihe dị ka akụkụ nke ọgwụgwọ siri ike.
Usoro usoro usoro ọgwụgwọ a tụrụ aro:
- ọrịa dystrophic nke cornea: s / c 0,5 ml otu ugboro n'ụbọchị n'otu ụbọchị 10-30,
- Ọbara intraocular na subconjunctival nke usoro dị iche iche: s / c ma ọ bụ p / b 0,5 ml otu ugboro kwa ụbọchị maka ụbọchị 10-15,
- Central diorophy dị n'etiti na akụkụ, akpọnwụ akpọnwụ nke angiosclerotic macular degeneration: 0,5 ml p / b otu ugboro kwa ụbọchị maka ụbọchị 10-15,
- thrombosis nke isi akwara nke retina na alaka ya: n / a 0,5 ml otu ugboro kwa ụbọchị na usoro nke 10-15 ụbọchị,
- myopia gbagwojuru anya: p / b 0,5 ml otu ugboro maka ụbọchị 10-30, ma ọ bụrụ na ọ dị mkpa ugboro 2-3 n'afọ, megharịa agụmakwụkwọ ahụ,
- mmerụ ahụ na nkụ nke cornea nke ọkwa nke abụọ: p / b 0,5 ml 1 oge kwa ụbọchị maka ụbọchị 10-15,
- mkpochi choroid na oge izizi nke ọgwụgwọ glaucoma: s / c ma ọ bụ p / b, 0,5-1 ml kwa ụbọchị, usoro ọgwụgwọ ahụ mejupụtara injections 10,
- nchedo azụ mgbe a na - etinye ọgwụ ụkwara (laser na mgbochi ụkwara): 0.5-1 ml p / b awa 24 na elekere 1 tupu coagulation, mgbe ahụ 0,5 ml otu ugboro kwa ụbọchị maka 2-10 ụbọchị.
Nsonaazụ
- mmeghachi omume mpaghara: ọkụ, ihe mgbu, hyperemia, itching, compaction nke anụ ahụ n'ụdị (ọ dịghị achọ ọgwụgwọ pụrụ iche, na-edozi onwe ya),
- Mmeghachi omume nfụkasị: nchacha ahụ, ahụji nke anụ ahụ, edema, hyperemia,
- ụra ụjọ, ura na-adị obere oge,
- site na akwara obi: akpukpo aru, okpukpo obara.
Mkparịta ụka ọgwụ ọjọọ
Methyl ethyl pyridinol ekwekọghị ọgwụ ọgwụ, ya mere amachibidoro ịgwakọta ya na otu ọgwụ na ọgwụ ndị ọzọ.
Ihe analogues nke Methylethylpyridinol bu: Vixipin, Cardioxypine, Methylethylpyridinol-Eskom, Emoxy-optician, Emoxibel, Emoxipin, Emoxipin-AKOS, wdg.
Nyocha banyere Methylethylpyridinol
Nyocha banyere methylethylpyridinol dị ole na ole, mana nke dị mma. Ọgwụ gosipụtara arụmọrụ dị elu, adịghị ọnụ.Agbanyeghị, dị ka ndị ọrịa si kwuo, ọ ka nnọọ adaba iji ọgwụ nwere otu ihe eji arụ ọrụ n'ụdị anya mmiri.
A na-ejikarị Methylethylpyridinol mee ihe maka ọrịa ophthalmological dị iche iche, yana maka nsogbu mgbasa na ọrịa obi.
Methylethylpyridinol: ọnụ ahịa dị na ahịa ọgwụ dị n'ịntanetị
Methylethylpyridinol 10 mg / ml ntụtụ maka 1 ml 10 PC.
Methylethylpyridinol ngwọta d / na. 10 mg / ml amp. 1ml Nke 10 ELLARA
Mmụta: Mahadum Ahụike Rostov State, ọpụrụiche "General Medicine".
A na - emejupụta ozi gbasara ọgwụ ahụ, enyere ya aka ka ọ nweta ihe ọ bụla, ọ naghị edochi ntuziaka gọọmentị. Medication medicationụ onwe gị ọgwụ dị ize ndụ nye ahụ ike!
Ọ na-emebu ikuku ahụ na-eme ka ahụ nwee ikuku oxygen. Agbanyeghị, echiche a kagburu. Ndị sayensị achọpụtala na mgbagharị, mmadụ na-eme ka ụbụrụ dị jụụ ma na-eme ka arụmọrụ ya ka mma.
Onye gụrụ akwụkwọ enweghị ike ịrịa ọrịa ụbụrụ. Ọrụ ọgụgụ isi na-enye aka n'ịmepụta anụ ahụ ọzọ iji kwụọ ndị ọrịa ọrịa.
Imeju bụ akwara kacha anyị n’ahụ. Ogo ya di 1.5 n'arọ.
O buru na inyinya inyinya, ino na ntukwasiri gi karie ka inwere n’agha. Naanị anwala igosipụta nkwupụta a.
Nwa nwoke onye Australia dị afọ 74, James Harrison ghọrọ onye na-enye ọbara n'ihe dị ka 1,000 ugboro. O nwere ụdị ọbara dị ụkọ, ọgwụ mgbochi nke enyere ụmụ amụrụ ọhụrụ aka na-arịa oke anaemia. N'ihi ya, onye Australia chebere ihe ruru ụmụaka nde abụọ.
E mepụtara akpa vibrator na narị afọ nke iri na itolu. Ọ rụrụ ọrụ na uzuoku ma na-bu n'obi na-agwọ ọrịa nwanyi.
Ọbara mmadụ "na-agba" site na arịa ndị nọ n'okpuru nrụgide dị ukwuu, ọ bụrụ na emebi iwu ya, ọ nwere ike gbaa 10 mita.
Ndi Sayensi si Mahadum Oxford mere otutu ihe omumu, mgbe ha biara na nkwubi okwu banyere na akwukwo nri nwere ike ibutere ụbara mmadu agha, ebe ọ na-ebute mbelata nke oke ya. Yabụ, ndị ọkà mmụta sayensị na-atụ aro ịhapụ iwepụ azụ na anụ na nri ha.
N'ime pasent 5 nke ndị ọrịa, Clomipramine antidepressant na-akpata mkpali.
N'oge ndụ, nkezi onye na-amịpụta obere mmiri mmiri abụọ.
N'oge ị na-arụ ọrụ, ụbụrụ anyị na-etinye oke nha anya ya na bọlbụ 10-watt. Yabụ na onyinyo nke oriọna dị n’elu isi gị n’oge ngosipụta nke echiche na-adọrọ mmasị adịghị anya n’eziokwu.
Ndị dọkịta ezé apụtawo n'oge na-adịbeghị anya. Laa azụ na narị afọ nke 19, ọ bụ ọrụ dịịrị onye na-edozi isi nkịtị iji wepụ ezé na-arịa ọrịa.
Emepụtara ọgwụ a maara nke ọma "Viagra" maka ọgwụgwọ nke ọbara mgbali elu.
Imirikiti ụmụ nwanyị na-enwe ike inweta obi ụtọ karịa ịtụgharị uche n'ahụ ha nke ọma n'enyo karịa inwe mmekọahụ. Yabụ, ụmụ nwanyị, gbaa mbọ maka nkwekọrịta.
E bugara ọtụtụ ọgwụ ka ọ bụrụ ọgwụ. Dịka ọmụmaatụ, azara ahịa Heroin na mbụ ka ọ bụrụ ọgwụ ụkwara. A na-atụkwa ọgwụ cocaine ka ọgwụ na-eme ka ọgwụ na-egbu egbu ma bụrụkwa ụzọ iji nwekwuo ntachi obi.
Polyoxidonium na-ezo aka ọgwụ immunomodulatory. Ọ na - arụ ọrụ n'akụkụ ụfọdụ nke sistem ahụ ọ na - alụso ọrịa ọgụ, si otú a na - enye aka ịbawanye ụba nke.
Mlọ ọgwụ
Olu nkesa - 5,2 lita. Mwepu ọkara ndụ bụ nkeji iri na asatọ. Nchịkọta zuru ezu bụ 0.2 l / min. Metabolized na imeju. Ọ bụ ya mere akụrụ.
Dika akụkụ nke usoro ọgwụgwọ mgbagwoju anya:
- Subconjunctival na intraocular ọbara nke usoro dị iche iche,
- Ọrịa angioretinopathy (gụnyere ọrịa mamịrị)
- Central na nsogbu ịkpa ike dystrophy,
- Thrombosis nke akwara azụ na akụkụ ya,
- Nroko nke myopia
- Angiosclerotic macular degeneration (akọrọ akọrọ),
- Detachment nke choroid na mgbe akwara ịwa ahụ maka glaucoma,
- Ọrịa dystrophic nke cornea,
- Mkpa ahụ, na-ere ọkụ na cornea,
- Ọgwụgwọ na mgbochi nke ọnya ihu nwere oke ọkụ (ìhè anyanwụ, radieshon laser n'oge coagulation laser).
Usoro onunu ogwu na nhazi
A na-eji ọgwụ ahụ eme ihe dị ka akụkụ nke ọgwụgwọ mgbagwoju anya.
Na subconjunctival na intraocular hemorrhages nke usoro dị iche iche - subconjunctival ma ọ bụ parabulbar 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ ya bụ ụbọchị 10-15.
Na angioretinopathy (gụnyere ọrịa mamịrị) - parabulbarno 0,5 ml 1 oge kwa ụbọchị. Usoro ya bụ ụbọchị iri.
Site na dystrophy nke etiti na akụkụ, yana antisclerotic macular degeneration (ụdị akọrọ) - parabulbar 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ ya bụ ụbọchị 10-15.
Na thrombosis nke akwara azụ ya na ngalaba ya - parabulbarno 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ ya bụ ụbọchị 10-15.
Na mgbagwoju anya myopia - parabulbarno 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ ahụ bụ ụbọchị 10-30, ọ ga-ekwe omume ịmegharịa N'ezie ahụ ugboro abụọ n'afọ.
Site na mkpochi choroid na ndị ọrịa nwere glaucoma na oge ọmụmụ - parabulbar ma ọ bụ subconjunctival 0.5-1.0 ml otu ugboro kwa ụbọchị abụọ. Usoro ọgwụgwọ ya bụ inje 10.
Maka mmerụ ahụ na ọkụ nke cornea nke ọkwa nke abụọ - parabulbarno 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ bụ inje 10-15.
Na ọrịa dystrophic nke cornea - subconjunctival 0,5 ml otu ugboro n'ụbọchị. Usoro ọgwụgwọ ya bụ ụbọchị 10-30.
Iji kpuchido retina n’oge coagulation laser (gụnyere mgbochi na mgbochi coagulation nke etuto ahụ), 0.5-1.0 ml nke 1% ngwọta (5-10 mg) parabulbarly 24 awa na 1 awa tupu coagulation, mgbe ahụ na otu doses ( 0,5 ml nke 1% ngwọta) 1 oge kwa ụbọchị maka ụbọchị 2-10.
Dodoụbiga ya ókè
Bụrụ na ị doụbiga mmanya ókè, ọ ga-ekwe omume ịbawanye uru nke ọgwụ ọgwụ na-akpata nsogbu.
Mgbaàmà: ịba ụba ọbara mgbali, nsogbu ma ọ bụ ụra, isi ọwụwa, ihe mgbu n'obi, ọgbụgbọ, ahụ erughị ala na mpaghara epigastric. Ọrịa nwere ike ibute ọbara.
Ọgwụ: ịkwụsị ọgwụ, usoro ọgwụgwọ Symptomatic, enweghị ọgwụ mgbochi akọwapụtara.
Ntụziaka pụrụ iche
Ekwesịrị ịmalite ọgwụgwọ na methylethylpyridinol n'okpuru nlekọta nke ọbara mgbali na coagulation ọbara.
Mmetụta ikike ịkwọ ụgbọ ala ma jiri usoro rụọ ọrụ
Site na mmepe nke ura, odi nkpa ka ighara iji ugbo ala na ihe ndi ozo na - agaghari, ma kpachara anya mgbe ị na - eme ihe egwu nwere ike ịchọ itinye uche gị na ọsọ ọsọ nke mmeghachi omume psychomotor.
Nkọwa nke ihe na-arụ ọrụ bụ Methylethylpyridinol / Methylaethylpiridinolum.
Usoro C8H11NO, aha kemịkal: 3-hydroxy-6-methyl-2-ethylpyridine hydrochloride.
Otu ọgwụ: ọgwụ hematotropic / antiplatelet, metabolism / antihypoxants na antioxidants, ọgwụ organotropic / ndị ọrụ obi / angioprotector na ndị na-edozi microcirculation, ọgwụ organotropic / ọgwụ ophthalmic.
Ihe ogwu ogwu: antihypoxic, antiaggregational, antioxidant, angioprotective, retinoprotective.
Ngwongwo ogwu
Methylethylpyridinol bụ angioprotector, antihypoxant na antioxidant, nwere akụrụngwa retinoprotective. Methylethylpyridinol na egbochi mgbochi usoro. Methylethylpyridinol na-eme ka akpụkpọ ahụ dịkwuo ala. Methylethylpyridinol na-eme ka microcirculation dịkwuo mma. Methyl ethyl pyridinol na-ebelata nchịkọta platelet na viscosity ọbara, na-ebelata ndepụta okwu coagulation, na-agbatị oge coagulation ọbara, na-abawanye ọdịnaya nke cyclic nucleotides (cyclic guanidine monophosphate na cyclic adenosine monophosphate) na anụ ahụ na platelet. Methylethylpyridinol nwere ọrụ fibrinolytic, na-ewusi mgbidi vaskụla ike, na-ebelata ike nke mgbidi vaskụla na ihe ize ndụ nke ọbara ọgbụgba, na-akwalite resorption nke hemorrhages. Methylethylpyridinol na-akwusi akpụkpọ ahụ nke sel ọbara na sel ọbara, na-eme ka nguzogide sel sel ọbara na-emetụta hemolysis na mmerụ ahụ. Methylethylpyridinol na-abawanye ọrụ nke enzymes antioxidant, na-egbochi oke ikuku nke lipids nke biosemranes n'efu. Methylethylpyridinol nwere mmetụta antitoxic, kwụsie cytochrome P-450. N'ọnọdụ ndị dị oke njọ, nke hypoxia na-abawanye na peroxidation ịba ụba, methylethylpyridinol na-ebuli usoro bioenergy. Na nnukwu ụbụrụ ischemic ọrịa ụbụrụ, methylethylpyridinol na-ebelata ogo ngosipụta akwara, na-eme ka nguzogide anụ ahụ na ischemia na hypoxia pụta. N'ihe banyere ọghọm ụbụrụ (ọbara ọgbụgba na ischemic), methylethylpyridinol na-enye aka na mgbazi nke dysfunctions autonomic, na-eme ka ọrụ mnemonic dịkwuo mma, ma na-eme ka iweghachi ọrụ ụbụrụ na-arụ ọrụ. Methylethylpyridinol na-ebelata nguzobe nke triglycerides, nwere mmetụta dị ala. Methylethylpyridinol na-akpo arịa nke obi, belata ischemic mbibi nke myocardium, na-arụ ọrụ nke usoro ngagharị nke obi yana nkwekọrịta nke obi. Methylethylpyridinol na-egbochi ogo nke necrosis, na-eme ka usoro mgbapụta na-adịwanye mma, na-edozi metabolism nke akwara obi na infarction myocardial. Methylethylpyridinol nwere mmetụta dị mma na usoro ọgwụgwọ nke infarction myocardial, na-ebelata ihe kpatara nnukwu nkụchi obi. N'ihe banyere ọdịda mgbasa, methylethylpyridinol na-enye aka na nhazi nke siste redox. Site n'ọbara mgbali elu, methyl ethyl pyridinol nwere mmetụta hypotensive. Methylethylpyridinol na-echebe mkpụkpọ aka ahụ site na ọkụ na-emebi ihe, na-eme ka microcirculation anya na -eme ihe, ma na - enyere aka idozi ọbara ọgbụgba dị n'ime.
Mgbe etinyere n’ime akwara njikọ, methylethylpyridinol na-abia n’ime akwara nke anya, ebe edobere ya ma bunye ya. Ntinye nke methylethylpyridinol na akwara nke anya dị elu karịa n'ọbara. Ọ na - ejikọ protein protein plasma dị ihe dị ka 42%. Site na nhazi nke intravenous nke methylethylpyridinol na 10 mg / kg, a hụrụ ndụ dị ala (nkeji 18), nke na-egosi oke oke mkpochasị methylethylpyridinol n'ọbara. Oge kpochapu bu nkeji 0.041. Methylethylpyridinol na-abanye ngwa ngwa na akwara na akwara, ebe a na-edebe ya ma na-akụ ya. Olu pụtara oke nke nkesa nke methylethylpyridinol bụ 5.2 lita. Mkpochasị nke methylethylpyridinol bụ 214.8 ml / min. Achọpụtara metabolites ise, nke ngwaahịa ngwaahịa ntụgharị methylethylpyridinol na-anọchi anya ya. Methylethylpyridinol bụ metabolized na imeju. Achọpụtara ihe dị ukwuu 2-ethyl-6-methyl-3-hydroxypyridine-phosphate n'ime imeju. Ọkpụkpụ methyl ethyl pyridinol na-amịpụta akụrụ. Na ọnọdụ pathologies, dịka ọmụmaatụ, na mgbaze ime mmụọ, ọgwụ ọgwụ nke methylethylpyridinol na-agbanwe: ọnụego ahụ na-agbada, n'ihi nke bioavailability nke methylethylpyridinol na-abawanye, oge obibi nke methylethylpyridinol n'ọbara na-abawanye, nke nwere ike ịbụ n'ihi nlọghachi ya na depot, gụnyere ischemic myo.
ọnya afọ mgbu, ọgbụgba ọbara na oge mgbake, ụbụrụ nke ụbụrụ na - adịghị ala ala, ihe ọghọm nke ọrịa ụbụrụ na - akpata nke nsị ụbụrụ na ọnya ụbụrụ na ụbụrụ ụbụrụ, ihe mgbu ụbụrụ, ọnya ụbụrụ, oge ọrụ nke epidural na hematomas subdural.
mgbochi ọrịa reperfusion syndrome, nnukwu myocardial infarction, angina pectoris na-ejighi ike.
n'ọbara nke intraocular na subconjunctival, ọbara ọgbụgba n'ime ihu nke anya, ọbara ọgbụgba n'ime sclera na ndị agadi (gụnyere mgbochi), angioretinopathy (gụnyere ọrịa angioretinopathy mamịrị), dystrophic keratitis, angiosclerotic maculodystrophy (akọrọ forma, thrombosis, thrombosis, thrombosis, thrombosis, thrombosis, thrombosis, thrombosis, thrombosis] isi akwara nke retina na alaka ya, chorioretinal dystrophy (gụnyere chorioretinal dystrophy nke atherosclerotic sitere), nchebe nke cornea (mgbe eyi ya. x lenses) na retina site na ikpughe ọkụ dị ukwuu (ya na ọnụnọ laser, anwụ anwụ na laser), ọrịa dystrophic nke cornea, nsogbu nke myopia, cataracts (gụnyere mgbochi nke ọrịa cataracts na ndị mmadụ karịa 40), trauma, mbufụt na nkụ nke cornea, ọnọdụ mgbe a wasịrị ya ahụ gbasara glaucoma na chochomentach, ịwa ahụ na anya.
Ofzọ eji methylethylpyridinol na dose
A na-eduzi Methylethylpyridinol intravenously, intramuscularly, subconjunctival, parabulbar, retrobulbar, tinye n'ime oghere njikọ.
N’ime nkwanye ugwu, ịkụnye 1 ruo 2 (1% ngwọta) ugboro abụọ ruo ụbọchị, oge ọ ga-eji gwọ ọrịa ga-adabere n’ọrịa ahụ wee bụrụ onye dọkịta kpebiri (ọ na-abụkarị ụbọchị 3 ruo ụbọchị 30), ọ bụrụ na a nabatara ọgwụ ahụ nke ọma ma nwee ihe ndị na-egosi, usoro ọgwụgwọ ahụ nwere ike ga - agagide ruo ọnwa 6 ma ọ bụ ugboro ugboro ugboro abụọ ruo atọ n'afọ.
A na-elekọta subconjunctival ma ọ bụ parabulbar otu ugboro n'ụbọchị ma ọ bụ ụbọchị ndị ọzọ. 0.2 - 0,5 ml nke 1% ngwọta (2 - 5 mg) na-achịkwa subconjunctively, a na-achịkwa 0,5 - 1 ml nke 1% (5 - 10 mg) na parabulbarly, oge ọgwụgwọ ahụ bụ 10 - ụbọchị 30, ọ ga-ekwe omume ikwugharị. N'ezie, ọ bụrụ na ọ dị mkpa, ugboro 2 ruo atọ kwa afọ. Ọ bụrụ na ọ dị mkpa, a na-edozi retrobulbar 0,5 na 1 ml nke 1% otu ugboro kwa ụbọchị maka ụbọchị 10 ruo 15. Na laser-coagulation (nke na-emebi ma na-egbochi coagulation nke etuto ahụ), 0.5-1 ml nke 1% ngwọta kwa ụbọchị na otu elekere tupu ebugharị coagulation retrobulbarly ma ọ bụ parabulbarly iji kpuchido retina, mgbe ahụ, a na-achịkwa 0,5 ml nke 1% ngwọta ozugbo ọ bụla ụbọchị maka ụbọchị 2 ruo 10.
Ọrịa angioretinopathy (gụnyere ọrịa angioretinopathy na-arịa ọrịa shuga): 0,5 ml parabulbarno (10 mg / ml methylethylpyridinol solution) otu ugboro n'ụbọchị, usoro ọgwụgwọ ahụ bụ ụbọchị iri. Ọkpụkpụ subconjunctival na intraocular nke usoro dị iche iche: parabulbarno ma ọ bụ subconjunctival 0,5 ml (10 mg / ml methylethylpyridinol solution) otu ugboro kwa ụbọchị, usoro ọgwụgwọ bụ ụbọchị 10-15. Central na peripheral chorioretinal dystrophy, angiosclerotic macular degeneration (akọrọ akọrọ): 0,5 ml parabulbarno (methylethylpyridinol solution 10 mg / ml) otu ugboro n'ụbọchị, usoro ọgwụgwọ bụ ụbọchị 10-15. Myopia gbara mgbagha: 0,5 ml parabulbarno (methylethylpyridinol ngwọta 10 mg / ml) otu ugboro n'ụbọchị, usoro ọgwụgwọ bụ ụbọchị 10-30, ọ ga-ekwe omume ikwugharị ahụ ugboro 2 ruo atọ kwa afọ. Thrombosis nke akwara azụ na akụkụ ya: 0,5 ml parabulbarno (methylethylpyridinol ngwọta 10 mg / ml) otu ugboro n'ụbọchị, usoro ọgwụgwọ bụ ụbọchị 10-15. Detachment nke choroid na ndị ọrịa nwere glaucoma na oge ọrụ: subconjunctival ma ọ bụ parabulbar 0,5 ruo 1.0 ml (10 mg / ml methylethylpyridinol ngwọta) otu ugboro kwa ụbọchị 2, usoro ọgwụgwọ bụ injections 10. Ọrịa dystrophic nke cornea: subconjunctival na dose nke 0,5 ml (10 mg / ml ngwọta nke methylethylpyridinol) otu ugboro n'ụbọchị, usoro ọgwụgwọ ahụ bụ ụbọchị 10-30. Ọkpụkpụ na ọkụ nke cornea nke ọkwa nke abụọ: 0,5 ml parabulbarno (methylethylpyridinol ngwọta 10 mg / ml) otu ugboro n'ụbọchị, usoro ọgwụgwọ bụ injections 10-15.
injection intravenously (20-40 na-akụ kwa nkeji), 20-30 ml nke ihe 3% (600-900 mg) 1 ugboro ugboro 3 maka ụbọchị 5-15, dabere na ngosipụta na usoro nke ọrịa ahụ (buru ụzọ methyl ethyl pyridinol 200 ml nke ihe ngwọta 5% nke dextrose ma ọ bụ 0.9% nke sodium chloride), mgbe ahụ, ha na-agbanye na ntụtụ intramuscular - 3 na 5 ml nke 3% ngwọta 2 ruo 3 ugboro n'ụbọchị maka 10 ruo ụbọchị 30.
a na - ejikwa ntụgharị nke ịwa ahụ (20-30 kwa nkeji) na ọgwụ kwa ụbọchị nke 5-10 mg / n'arọ maka ụbọchị 10-12, wee gbanwee gaa na nsị intramuscular nke 2-10 ml (ihe ngwọta na 30 mg / ml) (60-300 mg ) Ugboro abụọ ruo atọ n'ụbọchị iri ruo ụbọchị iri atọ.
Ejiri Methylethylpyridinol dịka akụkụ nke ọgwụgwọ mgbagwoju anya.
Ọgwụgwọ methyl ethyl pyridinol ga-emerịrị n'okpuru nchịkwa ọbara coagulation na usoro anticoagulation na ọbara mgbali.
Ọ bụrụ na ọ dị mkpa iji methylethylpyridinol n'ụdị nke anya na-ada na ọgwụ ndị ọzọ n'ụdị nke anya anya, etinyere methylethylpyridinol ikpeazụ mgbe emesịrị ị completeụ ọgwụ ọ bụla (opekata mpe 15).
N'oge ọgwụgwọ na methyl ethyl pyridinol, karịsịa ọnụnọ ụra, na-ebelata ọbara mgbali, a na-atụ aro ka ịghara itinye aka na ihe omume ndị dị ize ndụ na-achọ ịbawanye anya na ọsọ nke mmeghachi omume psychomotor (gụnyere ịkwọ ụgbọala, usoro).
Ime na lactation
Ojiji nke methylethylpyridinol bụ contraindicated n'oge ime na lactation, ebe enwebeghị ọmụmụ ihe zuru oke ma na-achịkwa nke ọma banyere nchekwa nke methylethylpyridinol n'oge afọ ime na lactation. N'oge ọgwụgwọ ya na methyl ethyl pyridinol, a ga-akwụsị inye ara ya.