NEURORUBINE FORTE LACTAB N20

• Ihe ngosi maka ojiji
• Ofzọ nke ngwa
• Nsonaazụ
• Mmekọrịta na ọgwụ ndị ọzọ
• Ihe ngbanwe
• Ime
• Dodoụbiga ya ókè
• Ọnọdụ nchekwa
• Mpempe mwepụta
• Ngwakọta
• Nhọrọ

Neurorubin-Forte Lactab - nkwadebe nke ihe mejupụtara nwere vitamin nke neurotropic nke otu B. Ihe ndị na - arụ ọrụ nke ọgwụ ahụ - vitamin B1, B6, B12 na - etinye aka na usoro biochemical nke na - achọpụta na nnyefe nke mkpachapụ anya na eriri akwara, metabolism, na metabolism nke ndị ọrụ mgbasa ozi na sistemụ ụjọ.
Thiamine (vitamin B1), nke dị n'ime membranes nke mkpụrụ ndụ akwara, na-etinye aka na ụzọ nke mmetụta akwara, na-eme ka mmụghachi nke akwara anụ ahụ dị. Mgbe ị na-etolite nnukwu nchịkọta nke thiamine n'ime ọbara, ọ na-akwalite mmepe nke mmetụta analgesic.
Pyridoxine (vitamin B6) na-emetụta nhazi na ọrụ nke anụ ahụ ụjọ, nke mbụ site na ịhazi metabolism nke amino acid, na-egbochi mkpo nke nsị neurotropic - amonia. Na-esonye na njikọ nke ndị mgbasa ozi dị iche iche: catecholamines, histamine, GABA, na-abawanye ụlọ ahịa intracellular nke magnesium, nke na-arụ ọrụ dị mkpa na metabolic, ya bụ, usoro ume na ọrụ nke sistemụ ụjọ.
Cyanocobalamin (vitamin B12) na-akpalite metabolic acid metabolism ma na-ekere òkè, yabụ, na ịnọgide na-enwe hematopoiesis, na-ebelata nociception neurogenic.
Mlọ ọgwụ
Thiamine mononitrate (vitamin B1) mgbe ọ nwesịrị nchịkwa ọnụ a na-abawanye na duodenum na obere eriri afọ. Ruo oke oke, a na-akụ ya na imeju na metabolites ya bụ isi bụ nitaminocarboxylic acid na pyramine (2,5-dimethyl-4-aminopyridimine). A na-ekepụta Metabolites yana obere mmiri nke thiamine na-agbanweghi agbanwe site na eriri afọ na akụrụ.
Pyridoxine hydrochloride (vitamin B6) na-abanye ngwa ngwa site na eriri afọ. A na-emegharị ya na imeju site na nguzobe nke ọgwụ ọgwụ na-arụ ọrụ nke pyridoxalphosphate na pyridoxamine. Vitamin B6 na-arụ ọrụ dị ka coenzyme mgbe phosphorylation nke ndị otu CH2OH nọ n'ọnọdụ nke ise, n'ụzọ ọzọ nguzobe pyridoxal 5-phosphate (PALP). Ihe dị ka 80% nke PALP na-ejikọ protein protein. Pyridoxine na - agbakọba n'ukwu akwara, akwara na akwara isi. Nkwadebe ikpeazụ maka metabolism nke pyridoxine bụ 4-pyridoxyl acid, nke akụrụ na-ewepụ.
Cyanocobalamin (Vitamin B12). A na-abanye cyanocobalamin ọnụ ọgụgụ ka ukwuu mgbe ọ gbasoro ya na ihe dị n'ime na Castle. Vitamin B12 na - achikota oke imeju. T1 / 2 site na ọbara bụ ihe dị ka ụbọchị ise, site na imeju - ihe dị ka afọ 1. A na - eji ya eme ihe karie ka bile na mmamiri.

Ihe ngosi maka ojiji

Neurorubin-Forte Lactab A na-atụ aro ka ị bụrụ akụkụ nke usoro ọgwụgwọ gụnyere:
- neuralgia, neuritis, polyneuritis,
- neuropathy, polyneuropathy (gụnyere ọrịa mamịrị, mmanya),
- Ngosipụta akwara nke osteochondrosis nke ọkpụkpụ azụ (sciatica, radiculopathy, syndromes-muscle).

Ofzọ nke ngwa

Neurorubin-Forte Lactab inye n'ime, tupu ma ọ bụ n'oge nri. Erichapụ ọgwụ ndị ahụ n’agaghị ata ata, were mmiri zuru oke sachaa ya.
A gwara ndị okenye ka ha were ọgwụ 1-2
Usoro ọgwụgwọ ya bụ izu anọ. Ọ bụ dọkịta na-abịa n'onwe ya kpebiri na ọ ga - eme ka usoro ọgwụgwọ dị iche iche ugboro ugboro.

Nsonaazụ

Mmeghachi omume nfụkasị: oge ​​ụfọdụ - itching, hives, ura ume, ụkwara Quincke, ujo anaphylactic.
Site na usoro digestive: oge ​​ụfọdụ - ọgbụgbọ, ọgbụgba afọ, mmụba nke AST.
Site na sisitemu obi: na nsogbu - tachycardia, ida, cyanosis, edema.
Ihe ezumike: oge ​​ụfọdụ - ịcha iyi a na-atụghị anya ya, mmetụta nke enweghị enyemaka, nkụchi, ụjọ, akwara, mgbochi nke zoro ezo prolactin.

Mmekọrịta na ọgwụ ndị ọzọ

Ebe ọ bụ na pyridoxine hydrochloride na-akpalite decarboxylation nke L-dopamine (levodopa) ma nwee ike belata mmetụta ọgwụgwọ nke ọgwụ a na ọgwụgwọ ndị ọrịa nwere ọrịa Parkinson, ojiji nke otu ọgwụ ndị a n'otu oge kwesịrị ka ewepụrụ.
Thiosemicarbazone na 5-fluorouracil belata ịdị irè nke vitamin B1, ịbụ ndị na-emegide ya.
Antacids na-ebelata nnabata nke vitamin B1.

Mpempe mwepụta

Neurorubin-Forte Lactab - ọgwụ.
Mbukota - ogwu iri.

Neurorubin-Forte Lactab nwere ihe na-arụ ọrụ: thiamine mononitrate (vit. B1) 200 mg, pyridoxine hydrochloride (vit. B6) 50 mg, cyanocobalamin (vit. B12) 1 mg.
Ndị pụrụ iche: hypromellose, mannitol, cellulose uzuzu uzuzu, cellulose microcrystalline, pregelatinized stachi, magnesium stearate, silloon silicon dioxide.
Ngwakọta nke akpụkpọ ahụ ihe nkiri: hypromellose, macrogol 6000, talc, titanium dioxide (E171), erythrosine (E127).

NEURORUBINE FORTE TABLETES N20

NEURORUBINE FORTE TABLETES N20

Aha: Neurorubine

Ihe ogwu ogwu:
Nkwadebe vitamin siri ike nwere vitamin B na-agbanye mmiri B vitamin na-arụ ọrụ dịgasị iche iche, n’agbanyeghi mmetụta ọgwụ ọgwụ yiri nke ahụ, vitamin nke ọ bụla nwere arụ ọrụ na ahụ mmadụ. Akpan akpan:
Vitamin B1 na-ekere òkè n'ọrụ na carbohydrate metabolism, ya na ụkọ ya na-abawanye na ole nke lactic na pyruvic asịd ke ahu. Na-esonye na nbibi na transamination nke amino acid, si otú a na-ahazi metabolism protein. Na metabolism abụba, vitamin B1 na-edozi nguzobe nke acid ma buru oke ntụgharị nke carbohydrates na abụba. Activedị vitamin nke nọ n'ọrụ na-akpali motility eriri afọ yana ọrụ nzuzo. Vitamin B1 na-eme ka oghere ion dị na membranes cell nke neurons, si otú a na-emetụta ụzọ nke mkpali dị na akụkụ akwara.

Vitamin B6 na-etinye aka na njikọ nke enzymes, protein na metabolism abụba. Activedị vitamin a na-arụ ọrụ na-etinye aka na mmeghachi omume enzymatic dị iche iche dịka coenzyme. Pyridoxine na-achịkwa njikọ nke neurotransmitters na synapses nke etiti na sistem akụkụ, na-ekere òkè na nguzobe nke myelin akpụkpọ ahụ nke neurons. Ọ na - eme ka mmepụta ume dị ike, na - ekere òkè na protein na metabolism, ma na - achịkwa njikọta haemoglobin.

Vitamin B12 na-arụ ọrụ dị mkpa na metabolism metabolism, na-achịkwa njikọ nke amino acid, purines na nucleic acid. Cyanocobalamin dị mkpa maka usoro nkịtị nke usoro nke myelination nke neurons na ịmepụta acetylcholine. Usoro dị ukwuu nke cyanocobalamin na-atụnye ụtụ n'inwe ike nke akwara ndị ahụ n'akụkụ akụkụ akwara ndị dị n'akụkụ ma na-akpali ịmụgharị akwara akwara. Otu ọrụ bụ isi nke vitamin B12 bụ ọgwụ mgbochi ya. Cyanocobalamin nwere mmetụta hematopoietic, na-akpali erythropoiesis. Vitamin B12 na-eme ka akwara heatatic na-adị mma, kwalite usoro coagulation ọbara, na-enyekwa aka belata cholesterol ọbara.

Ọgwụ Neurorubin nwere ọgwụ ọgwụgwọ dị elu nke vitamin ndị a dị n'elu, nke jikọtara aka na nhazi nke ọrụ nke sistem ma na-ahazi akwara, carbohydrate na protein metabolism. Na mgbakwunye, ngwakọta nke vitamin B a na-enyere aka belata ihe mgbu na neuralgia nke usoro dị iche iche.

The pharmacokinetics nke ọgwụ Neurorubin bụ n'ihi na pharmacokinetic Njirimara nke mejupụtara mejupụtara:
Thiamine mononitrate mgbe nchịkwa ọnụ gasịrị, ịmịpụta nke thiamine na-aputa ihe n’etiti obere eriri afọ, duodenum na jejunum. A na-etinye ntakịrị ọgwụ nke ọgwụ na imeju, a na-eji ọgwụ ahụ metabolized n'ime ahụ ya na ịmepụta etisinocarboxylic acid na pyramine. Nkeji 30 mgbe nchịkwa ọnụ gasịrị, itinye uche nke ọgwụ n'ọbara dị ala karịa akụkụ ahụ yana anụ ahụ. Site na ahụ ya na akụrụ ya na site na eriri afọ ya, na-agbanweghi agbanwe ma n’ụdị nke metabolites.
Pyridoxine hydrochloride na-etinye obi gị dum na eriri afọ, metabolized n'ime ahụ yana ịmepụta metabolites dị ike nke pyridoxal na pyridoxamine. Na mgbakwunye, pyridoxal-5-phosphate bụ ụdị ọgwụ a na-arụ ọrụ, nke na-arụ ọrụ nke coenzyme ahụ. Ejiri Pyridoxine dị elu nke na-egbochi protein protein (ihe ruru 80%). Achọpụtara nchịkọta ọgwụ na imeju, akwara na sistemụ akwara. Site na ahụ ya site na akụrụ n'ụdị metabolites ndị na - arụ ọrụ na arụ ọrụ.

Maka inweta cyanocobalamin nkịtị n'ime eriri afọ ha, ọnụnọ nke Castle ihe dị mkpa, nke na -echebe nnabata ọgwụ ọ bụla n’esegharị usoro. Metabolism nke cyanocobalamin, n'ihi nke a na-akpụ akpụ metabolite adenosylcobalamin, na-apụta na anụ ahụ. A na-akpụpụ ya na mmamịrị na bile. Ọ na-agbakọ na imeju. Ọkara ndụ nke ọgwụ ahụ site na plasma ọbara bụ ụbọchị 5, site na anụ imeju - ihe dị ka afọ 1.

Ihe ngosi maka ojiji:
A na-eji ọgwụ ahụ eme ihe n'ọnọdụ ndị metụtara njiri mara nke hypovitaminosis nke vitamin B na ahụ.
A na-eji mbadamba ihe mkpuchi fim, Neurorubin-Forte Lactab na usoro ọgwụgwọ siri ike nke ọrịa ndị a:
Mgbu na nnukwu ala na-adịghị ala ala nke neuritis na polyneuritis,
Neuralgia, ma mebie akụkụ ahụ ụjọ n'oge mmanya na - eji ihe dị iche iche xụbiga mmanya ókè,
Polyneuropathy na-arịa ọrịa mamịrị.
A na-eji ọgwụ ntụtụ Neurorubin eme ihe dị ka monotherapy ma ọ bụ yana ọgwụ ndị ọzọ maka ọrịa ndị a:
Neuropathies, gụnyere mpaghara, bụ ndị mmanya na-egbu.
Polyneuropathies na-arịa ọrịa mamịrị.
Vitamin B hypovitaminosis, beriberi akọrọ na mmiri.
Neuralgia, gụnyere cervicobrachial na trigeminal neuralgia.
Ọrịa na-adịghị ala ala na ọrịa na-adịghị ala ala na polyneuritis nke etiologies dị iche iche.

Usezọ iji:
Usoro ọgwụgwọ nke ọgwụ ọ bụla na oge ọ ga-agwọ ọrịa kpebisiri ike na ndị dibịa bekee ga-ekpebi onye ọrịa ọ bụla.
Mpempe akwụkwọ mkpuchi, Neurorubin-Forte Lactab ka a na-ewere ọnụ ọnụ mmiri zuru oke, ọkacha mma tupu nri ma ọ bụ n'oge nri, a naghị atụ aro ya kee ma ọ bụ taa mbadamba ihe mkpuchi. A na-edenye ndị okenye okenye mbadamba 1-2 kwa ụbọchị. Oge ọgwụgwọ ọ na-abụkarị ọnwa 1.

A na-eji ọgwụ mgbochi irighiri Neurorubin mee ihe maka irighiri akwara intramuscular; a na-atụ aro injections dị na okirikiri nke akwara gluteal.
Usoro onunu ogwu ya na ugboro ole nke inpa na-adabere ogo hypovitaminosis.
N'ọnọdụ dị njọ, a na-enye ọgwụ 3 ml nke ọgwụ kwa ụbọchị ma ọ bụ 1 oge n'ime ụbọchị 2 ruo mgbe ike nke mgbu mgbu belatara, mgbe nke ahụ gasịrị, ha na-agbanye 3 ml nke ọgwụ 1-2 ugboro na 7 ụbọchị.
N'ọnọdụ oke ogo, a na-enyekarị 3 ml nke ọgwụ ka ọ bụrụ 1-2 ugboro n'ime ụbọchị 7.
Ogologo oge ọgwụgwọ parenteral na Neurorubin dabere na ihe kpatara hypovitaminosis. Mgbe ị na-eme ọgwụ ogologo oge, a ga-enyocha usoro nyocha ụlọ ọnwa isii ọ bụla.

Mmetụta ọghọm:
Mgbe ị na-eji ọgwụ ahụ eme ihe na ndị ọrịa, a hụrụ nsogbu ndị a
Site na usoro digestive: ọgbụgbọ, ọgbụgbọ, ubara ọkwa nke hepatic transaminases n'ime ọbara. N'ime ndị ọrịa nwere ọgụgụ isi na-abawanye ụba, ọbara ọgbụgba dị n'ime eriri mara mgbe ha na-a theụ ọgwụ.
Site na sistemụ etiti na akụkụ: isi ike, isi ọwụwa, isi ọwụwa. N'ọnọdụ ndị dịpụrụ adịpụ, nchekasị, ụba iwe na oke nchegbu kwuru. Mgbe ha na-a theụ ọgwụ ahụ na oke doses, ụfọdụ ndị ọrịa chọpụtara ihe na-eme neuropathy akwara ọgụ, nke na-eme mgbe ịkwụsị ọgwụ ahụ.

Site na sisitemu obi: tachycardia, ndaghari nkewa (a choputara na ndi ọrịa nwere udiri mmadu karie).
Mmeghachi omume nfụkasị: ọnya akpụkpọ, ọnya, urticaria, mgbe ị na-ewere ọgwụ dị elu na ndị ọrịa, a chọpụtara mmepe nke otutu.
Mmetụta ọzọ: cyanosis, edere edere, sweating. N'ime ndị ọrịa na-ata ahụhụ site na mmetụta nke ọgwụ ahụ, mmeghachi omume anaphylactoid, gụnyere edegharị Quincke. Site na nchịkwa ọgwụ ọgwụ na ndị ọrịa na-arịa ọrịa shuga na vitamin B, ujo anaphylactic nwere ike ịmalite.

Contraindications:
Mmụba uche mmadụ n'otu n'otu na ọgwụ ndị metụtara ọgwụ.
Edere ya nke ọma na ndị ọrịa na-arịa ọrịa psoriasis, ebe ọ bụ na cyanocobalamin nwere ike ịkpalite ajọ ọrịa na psoriasis.
Achọpụtaghị ọgwụ ahụ Neurorubin n'ụdị ihe eji agwọ mmadụ ma ọ bụ mgbe a tụrụ ime ya na mgbe a na-enye ya ara, yana ọgwụgwọ maka ụmụaka na-erubeghị afọ 16.

Ime
Ọgwụ na-agafe mgbochi nke hematoplacental ma kpebisie ike na mmiri ara. Enweghị data na nchekwa nke ọgwụ n'oge afọ ime na lactation. Onye dibia bekee g’enye ogwu ogwu n’oge ogu ma oburu na uru nne a choro ga-akari iru nwa ebu n’afọ. Ọ bụrụ na ọ dị mkpa ịde ọgwụ ahụ n'oge a na-enye nwa ara, ọ dị mkpa ikpebi nkwụsị nke ị breastụ ara.

Mmekọrịta na ọgwụ ndị ọzọ:
Iji otu oge, ọgwụ a na-ebelata ọgwụ ọgwụgwọ levodopa, nke a ga-echebara echiche mgbe ị na-agwọ ndị ọrịa nwere ọrịa Parkinson na izere otu oge nke ọgwụ ndị a.
Iji otu oge, ọgwụ Neurorubin na-akwalite nsị nke isoniazid.
Neurorubin n'ihi vitamin B6 ya nwere ike belata ike altretamine na iji otu oge.
Thiosemicarbazone na fluorouracil bụ ndị na-emegide vitamin B1.
Ọgwụ ndị na-egbochi ihe ọkụkụ na antacid iji belata nnabata nke ọgwụ Neurorubin-Forte Lactab.

Dodoụbiga ya ókè
N'ihi ị overụ ọgwụ ọ theụdoụ gabigara ókè nke ndị ọrịa, a na-achọpụta mmụba nke nsonaazụ ya.
Enweghị ọgwụ mgbochi akọwapụtara. Ọ bụrụ na ị doụbiga ihe ọ ,ụ ,ụ, ịricụ ọgwụ gastric na nchịkwa nke enterosorbents ga-egosipụta. Usoro ọgwụgwọ ahụ bụ Symptomatic. Site na mmepe nke ujo anacticlactic, a na-eji glucocorticosteroids systemic na antihistamines.

Mwepụta weputara:
Mbadamba ụrọ, ihe mkpuchi na fim, mbadamba iri na paịlị, ọnya abụọ dị na igbe kaadi.
Ngwọta ogwu ogwu 3 ml na ampoule, 5 ampoules na kaadiboodu.

Ọnọdụ nchekwa:
A na-atụ aro ọgwụ a ka echekwa ya n'ebe ọkpọka naanị maka ìhè anyanwụ. A na-atụ aro ka ị chekwa mbadamba nkume nke Neurorubin-Forte Lactab ka ọ bụrụ ihe nchekwa Celsius 15 ruo 25.
A na-atụ aro maka ọgwụ mgbochi Neurorubin ka ọ chekwaa ya na ogo Celsius 2 ruo 8.
Ndụ nchekwa nke ọgwụ n’ụdị ihe ngwọta maka injection bụ afọ 3.
Ndụ nchekwa nke ọgwụ n'ụdị mbadamba akwụkwọ bụ afọ 4.

Mmekorita:
Neurovitan, Milgamma.

Ngwakọta:
3 ml (1 ampoule) nke ntụtụ nwere:
Thiamine hydrochloride - 100 mg,
Pyridoxine hydrochloride - 100 mg,
Cyanocobalamin - 1 mg.
Ndị pụrụ iche.

1 otu mbadamba ihe mkpuchi fim nwere:
Thiamine mononitrate - 200 mg,
Pyridoxine hydrochloride - 50 mg,
Cyanocobalamin - 1 mg.
Ndị pụrụ iche.

Ntị!
Tupu ị .ụ ọgwụ ahụ Neurorubin should kwesịrị ịgwa dọkịta. A na-enye akwụkwọ ntuziaka a na ntụgharị n'efu yana ebumnuche maka ebumnuche ozi. Maka ozi ndị ọzọ, biko rụtụ aka na nkọwapụta onye nrụpụta.
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Aha: Neurorubine

Ihe ogwu ogwu:
Nkwadebe vitamin siri ike nwere vitamin B na-agbanye mmiri B vitamin na-arụ ọrụ dịgasị iche iche, n’agbanyeghi mmetụta ọgwụ ọgwụ yiri nke ahụ, vitamin nke ọ bụla nwere arụ ọrụ na ahụ mmadụ. Akpan akpan:
Vitamin B1 na-ekere òkè n'ọrụ na carbohydrate metabolism, ya na ụkọ ya na-abawanye na ole nke lactic na pyruvic asịd ke ahu. Na-esonye na nbibi na transamination nke amino acid, si otú a na-ahazi metabolism protein. Na metabolism abụba, vitamin B1 na-edozi nguzobe nke acid ma buru oke ntụgharị nke carbohydrates na abụba. Activedị vitamin nke nọ n'ọrụ na-akpali motility eriri afọ yana ọrụ nzuzo. Vitamin B1 na-eme ka oghere ion dị na membranes cell nke neurons, si otú a na-emetụta ụzọ nke mkpali dị na akụkụ akwara.

Vitamin B6 na-etinye aka na njikọ nke enzymes, protein na metabolism abụba. Activedị vitamin a na-arụ ọrụ na-etinye aka na mmeghachi omume enzymatic dị iche iche dịka coenzyme. Pyridoxine na-achịkwa njikọ nke neurotransmitters na synapses nke etiti na sistem akụkụ, na-ekere òkè na nguzobe nke myelin akpụkpọ ahụ nke neurons. Ọ na - eme ka mmepụta ume dị ike, na - ekere òkè na protein na metabolism, ma na - achịkwa njikọta haemoglobin.

Vitamin B12 na-arụ ọrụ dị mkpa na metabolism metabolism, na-achịkwa njikọ nke amino acid, purines na nucleic acid. Cyanocobalamin dị mkpa maka usoro nkịtị nke usoro nke myelination nke neurons na ịmepụta acetylcholine. Usoro dị ukwuu nke cyanocobalamin na-atụnye ụtụ n'inwe ike nke akwara ndị ahụ n'akụkụ akụkụ akwara ndị dị n'akụkụ ma na-akpali ịmụgharị akwara akwara. Otu ọrụ bụ isi nke vitamin B12 bụ ọgwụ mgbochi ya. Cyanocobalamin nwere mmetụta hematopoietic, na-akpali erythropoiesis. Vitamin B12 na-eme ka akwara heatatic na-adị mma, kwalite usoro coagulation ọbara, na-enyekwa aka belata cholesterol ọbara.

Ọgwụ Neurorubin nwere ọgwụ ọgwụgwọ dị elu nke vitamin ndị a dị n'elu, nke jikọtara aka na nhazi nke ọrụ nke sistem ma na-ahazi akwara, carbohydrate na protein metabolism. Na mgbakwunye, ngwakọta nke vitamin B a na-enyere aka belata ihe mgbu na neuralgia nke usoro dị iche iche.

The pharmacokinetics nke ọgwụ Neurorubin bụ n'ihi na pharmacokinetic Njirimara nke mejupụtara mejupụtara:
Thiamine mononitrate mgbe nchịkwa ọnụ gasịrị, ịmịpụta nke thiamine na-aputa ihe n’etiti obere eriri afọ, duodenum na jejunum. A na-etinye ntakịrị ọgwụ nke ọgwụ na imeju, a na-eji ọgwụ ahụ metabolized n'ime ahụ ya na ịmepụta etisinocarboxylic acid na pyramine. Nkeji 30 mgbe nchịkwa ọnụ gasịrị, itinye uche nke ọgwụ n'ọbara dị ala karịa akụkụ ahụ yana anụ ahụ. Site na ahụ ya na akụrụ ya na site na eriri afọ ya, na-agbanweghi agbanwe ma n’ụdị nke metabolites.
Pyridoxine hydrochloride na-etinye obi gị dum na eriri afọ, metabolized n'ime ahụ yana ịmepụta metabolites dị ike nke pyridoxal na pyridoxamine. Na mgbakwunye, pyridoxal-5-phosphate bụ ụdị ọgwụ a na-arụ ọrụ, nke na-arụ ọrụ nke coenzyme ahụ. Ejiri Pyridoxine dị elu nke na-egbochi protein protein (ihe ruru 80%). Achọpụtara nchịkọta ọgwụ na imeju, akwara na sistemụ akwara. Site na ahụ ya site na akụrụ n'ụdị metabolites ndị na - arụ ọrụ na arụ ọrụ.

Maka inweta cyanocobalamin nkịtị n'ime eriri afọ ha, ọnụnọ nke Castle ihe dị mkpa, nke na -echebe nnabata ọgwụ ọ bụla n’esegharị usoro. Metabolism nke cyanocobalamin, n'ihi nke a na-akpụ akpụ metabolite adenosylcobalamin, na-apụta na anụ ahụ. A na-akpụpụ ya na mmamịrị na bile. Ọ na-agbakọ na imeju. Ọkara ndụ nke ọgwụ ahụ site na plasma ọbara bụ ụbọchị 5, site na anụ imeju - ihe dị ka afọ 1.

Ihe ngosi maka ojiji:
A na-eji ọgwụ ahụ eme ihe n'ọnọdụ ndị metụtara njiri mara nke hypovitaminosis nke vitamin B na ahụ.
A na-eji mbadamba ihe mkpuchi fim, Neurorubin-Forte Lactab na usoro ọgwụgwọ siri ike nke ọrịa ndị a:
Mgbu na nnukwu ala na-adịghị ala ala nke neuritis na polyneuritis,
Neuralgia, ma mebie akụkụ ahụ ụjọ n'oge mmanya na - eji ihe dị iche iche xụbiga mmanya ókè,
Polyneuropathy na-arịa ọrịa mamịrị.
A na-eji ọgwụ ntụtụ Neurorubin eme ihe dị ka monotherapy ma ọ bụ yana ọgwụ ndị ọzọ maka ọrịa ndị a:
Neuropathies, gụnyere mpaghara, bụ ndị mmanya na-egbu.
Polyneuropathies na-arịa ọrịa mamịrị.
Vitamin B hypovitaminosis, beriberi akọrọ na mmiri.
Neuralgia, gụnyere cervicobrachial na trigeminal neuralgia.
Ọrịa na-adịghị ala ala na ọrịa na-adịghị ala ala na polyneuritis nke etiologies dị iche iche.

Usezọ iji:
Usoro ọgwụgwọ nke ọgwụ ọ bụla na oge ọ ga-agwọ ọrịa kpebisiri ike na ndị dibịa bekee ga-ekpebi onye ọrịa ọ bụla.
Mpempe akwụkwọ mkpuchi, Neurorubin-Forte Lactab ka a na-ewere ọnụ ọnụ mmiri zuru oke, ọkacha mma tupu nri ma ọ bụ n'oge nri, a naghị atụ aro ya kee ma ọ bụ taa mbadamba ihe mkpuchi. A na-edenye ndị okenye okenye mbadamba 1-2 kwa ụbọchị. Oge ọgwụgwọ ọ na-abụkarị ọnwa 1.

A na-eji ọgwụ mgbochi irighiri Neurorubin mee ihe maka irighiri akwara intramuscular; a na-atụ aro injections dị na okirikiri nke akwara gluteal.
Usoro onunu ogwu ya na ugboro ole nke inpa na-adabere ogo hypovitaminosis.
N'ọnọdụ dị njọ, a na-enye ọgwụ 3 ml nke ọgwụ kwa ụbọchị ma ọ bụ 1 oge n'ime ụbọchị 2 ruo mgbe ike nke mgbu mgbu belatara, mgbe nke ahụ gasịrị, ha na-agbanye 3 ml nke ọgwụ 1-2 ugboro na 7 ụbọchị.
N'ọnọdụ oke ogo, a na-enyekarị 3 ml nke ọgwụ ka ọ bụrụ 1-2 ugboro n'ime ụbọchị 7.
Ogologo oge ọgwụgwọ parenteral na Neurorubin dabere na ihe kpatara hypovitaminosis. Mgbe ị na-eme ọgwụ ogologo oge, a ga-enyocha usoro nyocha ụlọ ọnwa isii ọ bụla.

Mmetụta ọghọm:
Mgbe ị na-eji ọgwụ ahụ eme ihe na ndị ọrịa, a hụrụ nsogbu ndị a
Site na usoro digestive: ọgbụgbọ, ọgbụgbọ, ubara ọkwa nke hepatic transaminases n'ime ọbara. N'ime ndị ọrịa nwere ọgụgụ isi na-abawanye ụba, ọbara ọgbụgba dị n'ime eriri mara mgbe ha na-a theụ ọgwụ.
Site na sistemụ etiti na akụkụ: isi ike, isi ọwụwa, isi ọwụwa. N'ọnọdụ ndị dịpụrụ adịpụ, nchekasị, ụba iwe na oke nchegbu kwuru. Mgbe ha na-a theụ ọgwụ ahụ na oke doses, ụfọdụ ndị ọrịa chọpụtara ihe na-eme neuropathy akwara ọgụ, nke na-eme mgbe ịkwụsị ọgwụ ahụ.

Site na sisitemu obi: tachycardia, ndaghari nkewa (a choputara na ndi ọrịa nwere udiri mmadu karie).
Mmeghachi omume nfụkasị: ọnya akpụkpọ, ọnya, urticaria, mgbe ị na-ewere ọgwụ dị elu na ndị ọrịa, a chọpụtara mmepe nke otutu.
Mmetụta ọzọ: cyanosis, edere edere, sweating. N'ime ndị ọrịa na-ata ahụhụ site na mmetụta nke ọgwụ ahụ, mmeghachi omume anaphylactoid, gụnyere edegharị Quincke. Site na nchịkwa ọgwụ ọgwụ na ndị ọrịa na-arịa ọrịa shuga na vitamin B, ujo anaphylactic nwere ike ịmalite.

Contraindications:
Mmụba uche mmadụ n'otu n'otu na ọgwụ ndị metụtara ọgwụ.
Edere ya nke ọma na ndị ọrịa na-arịa ọrịa psoriasis, ebe ọ bụ na cyanocobalamin nwere ike ịkpalite ajọ ọrịa na psoriasis.
Achọpụtaghị ọgwụ ahụ Neurorubin n'ụdị ihe eji agwọ mmadụ ma ọ bụ mgbe a tụrụ ime ya na mgbe a na-enye ya ara, yana ọgwụgwọ maka ụmụaka na-erubeghị afọ 16.

Ime
Ọgwụ na-agafe mgbochi nke hematoplacental ma kpebisie ike na mmiri ara. Enweghị data na nchekwa nke ọgwụ n'oge afọ ime na lactation. Onye dibia bekee g’enye ogwu ogwu n’oge ogu ma oburu na uru nne a choro ga-akari iru nwa ebu n’afọ. Ọ bụrụ na ọ dị mkpa ịde ọgwụ ahụ n'oge a na-enye nwa ara, ọ dị mkpa ikpebi nkwụsị nke ị breastụ ara.

Mmekọrịta na ọgwụ ndị ọzọ:
Iji otu oge, ọgwụ a na-ebelata ọgwụ ọgwụgwọ levodopa, nke a ga-echebara echiche mgbe ị na-agwọ ndị ọrịa nwere ọrịa Parkinson na izere otu oge nke ọgwụ ndị a.
Iji otu oge, ọgwụ Neurorubin na-akwalite nsị nke isoniazid.
Neurorubin n'ihi vitamin B6 ya nwere ike belata ike altretamine na iji otu oge.
Thiosemicarbazone na fluorouracil bụ ndị na-emegide vitamin B1.
Ọgwụ ndị na-egbochi ihe ọkụkụ na antacid iji belata nnabata nke ọgwụ Neurorubin-Forte Lactab.

Dodoụbiga ya ókè
N'ihi ị overụ ọgwụ ọ theụdoụ gabigara ókè nke ndị ọrịa, a na-achọpụta mmụba nke nsonaazụ ya.
Enweghị ọgwụ mgbochi akọwapụtara. Ọ bụrụ na ị doụbiga ihe ọ ,ụ ,ụ, ịricụ ọgwụ gastric na nchịkwa nke enterosorbents ga-egosipụta. Usoro ọgwụgwọ ahụ bụ Symptomatic. Site na mmepe nke ujo anacticlactic, a na-eji glucocorticosteroids systemic na antihistamines.

Mwepụta weputara:
Mbadamba ụrọ, ihe mkpuchi na fim, mbadamba iri na paịlị, ọnya abụọ dị na igbe kaadi.
Ngwọta ogwu ogwu 3 ml na ampoule, 5 ampoules na kaadiboodu.

Ọnọdụ nchekwa:
A na-atụ aro ọgwụ a ka echekwa ya n'ebe ọkpọka naanị maka ìhè anyanwụ. A na-atụ aro ka ị chekwa mbadamba nkume nke Neurorubin-Forte Lactab ka ọ bụrụ ihe nchekwa Celsius 15 ruo 25.
A na-atụ aro maka ọgwụ mgbochi Neurorubin ka ọ chekwaa ya na ogo Celsius 2 ruo 8.
Ndụ nchekwa nke ọgwụ n’ụdị ihe ngwọta maka injection bụ afọ 3.
Ndụ nchekwa nke ọgwụ n'ụdị mbadamba akwụkwọ bụ afọ 4.

Mmekorita:
Neurovitan, Milgamma.

Ngwakọta:
3 ml (1 ampoule) nke ntụtụ nwere:
Thiamine hydrochloride - 100 mg,
Pyridoxine hydrochloride - 100 mg,
Cyanocobalamin - 1 mg.
Ndị pụrụ iche.

1 otu mbadamba ihe mkpuchi fim nwere:
Thiamine mononitrate - 200 mg,
Pyridoxine hydrochloride - 50 mg,
Cyanocobalamin - 1 mg.
Ndị pụrụ iche.

Ntị!
Tupu ị .ụ ọgwụ ahụ Neurorubin should kwesịrị ịgwa dọkịta. A na-enye akwụkwọ ntuziaka a na ntụgharị n'efu yana ebumnuche maka ebumnuche ozi. Maka ozi ndị ọzọ, biko rụtụ aka na nkọwapụta nke ndị nrụpụta.
Isi mmalite nke nkọwa, ntuziaka maka iji ọgwụ (ọgwụ): Site "Piluli - Medicine si A ruo Z"

Iji na-akpaghị aka ịchọ ọnụahịa kachasị mma maka ọgwụ na ụdị analogues ka NEURORUBINE FORTE LACTAB N20 pịa ebe a:

• Ihe osise bu naanị ihe atụ. Ihe omuma ogwu di na saịtị a nwere ike di iche na udi ya.

Omume ọgwụ

Ọgwụ nwere vitamin atọ na-eme ma kwado mmemme nke ibe ha.

Vitamin B1, ma ọ bụ thiamine, na-etinye aka na mmeghachi omume redox nke anụ ahụ dịka coenzyme. Ọ na-eji ngwaahịa metabolic dị na-egbu egbu - pyruvic na lactic acid. Na -emezi usoro carbohydrate, abụba na protein metabolism.

Thiamine na-akwalite usoro nke mkpali n'akụkụ njedebe akwara, na-eme ka metabolism nke neurons dịkwuo mma. Na-edozi motility eriri afọ na usoro nri. Ọ nwere mmetụta analgesic dị nro na nnukwu nchịkọta.

N’inweghi vitamin B1, nsogbu nke akwara (polyneuritis) na-emetụta, mmetu uche, ọrịa Wernicke-Korsakov (yana ị withụ mmanya).

Vitamin B6, pyridoxine - ihe metụtara protein na abụba metabolism, usoro ume nke mkpụrụ ndụ akwara. Ọ bụ coenzyme nke transamination nke amino asịd na imeju. Na-akwalite njikọta nke usoro akwara kachasị mkpa nke etiti na akụkụ akwara: adrenaline, norepinephrine, dopamine. Ọ na - eme ka ọnọdụ nke imeju dịkwuo mma, na - ebelata ngosipụta nke ọrịa premenstrual na ụmụ nwanyị: isi ọwụwa, ọria, na ọnọdụ na - akawanye njọ. So na njikọta haemoglobin.

N’inweghi vitamin B6, ike ọgwụgwụ, iza, mmụba nke prolactin homonụ, idapụ ntutu, ụsụụ ọbara na ọnya afọ nwere ike ime.

Vitamin B12, cyanocobalamin - mmiri ọgwụ nwere kemikal cobalt. Emetụta protein, abụba metabolism. Na-akwalite nkewa sel site na ịhazi njikọ nke nucleic acid. Na-abawanye ọnụ ọgụgụ mkpụrụ ndụ ọbara uhie na ọbara, na-ekere òkè na nkewa ha n'ihi usoro methylation. Na-ebelata cholesterol ọbara, homocysteine. Mmetụta dị mma na sistemụ akwara na akụkụ etiti. Na-akwalite omume dị njọ nke ihe mgbu yana eriri akwara.

Na enweghi vitamin B12, nsogbu ndi mmadu n’arụ aru nke ọgirigi azụ, oke anaemia, mmụba nke ọkwa bilirubin, cholesterol, homocysteine ​​na imeju nwere ike ime.

Na enweghi vitamin B12, abuba imeju nwere ike ime.

Mlọ ọgwụ

Mgbe a na -ekwu ya okwu ọnụ, a na-etinye mmiri thiamine na obere eriri afọ ma banye na imeju. A na-emegharị ụfọdụ n'ime ya. Ọ bụ metabolized ma wepụta ya n'ụdị nke thiamincarboxylic acid, dimethylaminopyrimidine. Obere obere na-agbanwegharị na mmamịrị.

Pyridoxine hydrochloride, mgbe a na-ewere ya ọnụ, ọ na-agbaso ike ma na-abanye umeji. Metabolized ka pyridoxalphosphate na pyridoxamine. Ọ na - ejikọ ndị na - ebu protein n'ime ọbara ma na - agbakọta na uru ahụ n'ụdị pyridoxalphosphate. A na-apụ ya n'ụdị pyridoxic acid.

Cyanocobalamin na-ahụ maka ahụ gị n'ihi ekele nke ihe dị n'ime Castle nke dị na afọ - gastromucoprotein. A na-etinye ya na eriri afọ, kee ya na ọbara yana ndị na - ebu protein - transcobalamin na alfa-1-globulin. Ọ na-agbakọ na imeju, ebe enwere ike ịchekwa ya ruo otu afọ. Ọbara ọkara nke ọbara bụ ụbọchị ise.

Ọkpụkpụ afọ

Ogbugbu, vomiting, obi mgbu, mgbu afọ.

Jiri na agadi

Anabatara ya maka iji ya mgbe dọkịta depụtara ya ma na-eburu n'uche mgbochi niile. Cyanocobalamin na-abawanye viscosity ọbara, yabụ na ọ nwere ike ime ka ohere nke thrombosis bawanye.

Cyanocobalamin na-abawanye viscosity ọbara, yabụ na ọ nwere ike ime ka ohere nke thrombosis bawanye.

Mmekọrịta na ọgwụ ndị ọzọ

Ihe anakpo ọgwụ na anwansi na-ebelata mmata nke ogwu. 6-fluorouracil, thiosemicarbazone - thiamine antagonists.

Vitamin B6 na-ebelata ọrụ nke ọgwụ anti-Parkinsonian Levodopa.

Vitamin B6 na-ebelata ọrụ nke ọgwụ anti-Parkinsonian Levodopa.

Nyocha Neurorubin Fort

Igor, onye gbara afọ 40, Samara

Azụtara m vitamin maka ọgwụgwọ nke osteochondrosis. Enwere mgbu na olu.Mgbe ha theụsịrị ọgwụ ahụ, ha mere ka ike gwụ ha. Ọ malitere inwe obi ụtọ karịa. Adịghị ike gafere n'ụtụtụ.

Anna, dị afọ 36, Kazan

Ọkpụkpụ ụkwụ na mkpịsị aka ya nwere nchegbu. Ọrịa neuropathologist nyere ọgwụ a. Ọrịa ahụ belatara. Mgbe iwere mbadamba nkume ndị ahụ, enwere nkụchi obi ntakịrị, ntuziaka na-egosi na ntuziaka ahụ. Enwere isi ọwụwa.

Ihe ngbanwe

Ejiri ọgwụ mgbochi.

Vitamin B ₁ Ọ bụ contraindicated maka ojiji na-ekwo ekwo ọrịa.

Vitamin B ₆ ọ contraindicated bụrụ na nke peptic ọnya nke afo na duodenum ke nnukwu ogbo (ebe ọ bụ na-abawanye na acidity nke gastric ihe ọ juiceụ gastụ kwere omume).

Vitamin B ₁₂ A machibidoro ya maka iji rụọ ọrụ na erythremia, erythrocytosis, thromboembolism.

Safetykpachapụrụ anya maka nchekwa maka ojiji

N'ihi amamịghe vitamin B ₁ , Na ₆ na B ₁₂ n'oge ọgwụgwọ, mmeghachi omume sitere na akpụkpọ anụ na anụ ahụ subcutaneous nwere ike ime.

Pyridoxine nwere ike kpalite ihe otutu ma ọ bụ nke anụ ahụ akpịrị ma ọ bụ kwalite ngosipụta nke ndị dị adị.

Site na iwebata vitamin ₁₂ ihe onyonyo a gha achoro, ya na inyocha ulo oru ihe omimi ma obu ihe ana - ele anya, nwere ike ghara inata ha.

Alcoholrinụ mmanya na tii na -ewe oji na -ebelata mmịpụta nke thiamine.

Verakingụ mmanya na-egbu sulphite (dị ka mmanya) na-abawanye mbibi nke mmiri.

N'ihi na ọgwụ ahụ nwere vitamin ₆ ekwesịrị iji nlezianya mee ihe na ndị ọrịa nwere ọrịa afọ na-egbu mgbu na duodenal ọnya, nke gosipụtara site na ezigharị azụ na arụ ọrụ hepatic.

Ndị ọrịa nwere neoplasms, ewezuga okwu ndị metụtara megaloblastic anaemia na ụkọ vitamin B. ₁₂ ekwesighi iji ogwu.

A na-eji ọgwụ ahụ eme ihe maka oké decompensation nke ọrịa obi na angina pectoris.

Jiri n'oge ime na lactation

Edere ọgwụ ahụ naanị mgbe nyochachara nke ọma banyere uru / ihe ọghọm ruru, ebe enweghi data zuru oke banyere nchekwa nke ọgwụ n'oge afọ ime.

Vitamin B ₁ , Na ₆ na B ₁₂ areụcha na mmiri ara ara. Nnukwu vitamin B nke dị elu ₆ nwere ike igbochi mmepụta mmiri ara ehi. Emebeghị nnyocha banyere ogo nke vitamin nke mmiri ara ara. Mkpebi ịhapụ ị breastụ ara ma ọ bụ ị theụ ọgwụ ahụ ga-emerịrị na-eburu n'uche mkpa ị takingụ ọgwụ maka nne ya. Ọ bụrụ na ọ dị mkpa, ị ofụ ọgwụ ahụ kwesịrị ịkwụsị inye nwa ara maka oge a.

Ikike iji metụta ọnụego mmeghachi omume mgbe ị na-anya ụgbọ ala ma ọ bụ usoro ndị ọzọ

Ọgwụ a anaghị emetụta ikike ịkwọ ụgbọala ma ọ bụ jiri usoro rụọ ọrụ.

N'ọnọdụ ebe enwere nkụda mmụọ n'oge ọgwụgwọ, mmadụ kwesịrị ịhapụ ịnya ụgbọ ala na iji usoro.

Ekwesighi inye umuaka ogwu ogwu a, ebe obu na enweghi ahuhu banyere iji ogwu eme ihe.

Dodoụbiga ya ókè

Vitamin B ₁ : nwere otutu ọgwụgwọ ọgwụgwọ. Doses dị elu (ihe karịrị 10 g) na-egosipụta mmetụta curariform, na-ebelata akụkụ nke akwara ozi.

Vitamin B ₆ : O nwere aru ojoo di ala. Ogologo oge (ihe kariri ọnwa 6-12) na usoro nke ihe karịrị 50 mg nke vitamin B ₆ kwa ụbọchị nwere ike ibute ọrịa ụbụrụ na-enwe nsogbu.

Iji Vitamin Efufefefe ₆ na doses karịa 1 g kwa ụbọchị ruo ọtụtụ ọnwa nwere ike ibute nsonaazụ neurotoxic.

Neuropathies nwere nsogbu ataxia na nsogbu nke uche, ihe ọdịdọ ahụ nwere mgbanwe na EEG, yana n'ọnọdụ ụfọdụ hypochromic anaemia na seborrheic dermatitis kọwara mgbe nchịkwa nke ≥ 2 g kwa ụbọchị.

Vitamin B ₁₂ : mgbe nchịkwa ọchịchị (na obere oge, mgbe nchịkwa ọnụ gasịrị), mmeghachi omume nfụkasị ahụ, ọrịa akpịrị eczematous na ụdị ọrịa akpịrị hụrụ na usoro ọnụọgụ dị elu karịa ka akwadoro.

Site na iji ogologo oge na oke onunu ogwu, imebi ọrụ nke enzymes imeju, ihe mgbu n'obi, na hypercoagulation ga-ekwe omume.

Usoro ọgwụgwọ maka igbu egbu egbu: mkpochapu ihe na - egbu egbu (na - eme ka ọ ghara ị ,ụ mmiri, hichaa afọ), jikoro iji belata mmụcha (ojiji nke unyi na - arụ ọrụ).

Nsonaazụ

Si dịghịzi usoro: hypersensitivity mmeghachi omume, ujo anaphylactic, ujo anaphylactic. Mmeghachi omume nfụkasị ahụ dị ụkọ.

Site na usoro endocrine: Ihe mgbochi prolactin bụ ihe mgbochi.

Si ụjọ usoro: ụjọ, iji ogologo oge (karịa ọnwa 6-12) nke vitamin ₆ na usoro onunu ogwu ≥ 50 mg kwa ụbọchị, nwere ike ibute neuropathy nsogbu ụfụ, ụjọ jijiji, ọrịa, isi ọwụwa, isi ọwụwa.

Si usoro obi: tachycardia, ida.

Na akụkụ nke akụkụ okuku ume, obi na mediastinum: cyanosis, ụkwara ume ọkụ.

Site na eriri afọ: ọrịa eriri afọ, gụnyere ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, mgbu nke afọ, ịba ụba acidity nke ihe ọ gastụ gastụ afọ.

Site na imeju na eriri afọ: mgbe ejiri ya na oke onunu ogwu, mmụba nke ọkwa glutamic acid-transmucosal transaminase (SGOT) n'ọbara.

Na akpụkpọ anụ ahụ ihe mbufụt, mmeghachi omume anụ ahụ, gụnyere pruritus, urticaria.

Ọrịa ndị ọzọ: ịatingụbiga ọ excessiveụ ókè, mmetụta nke adịghị ike, dizzness, malaise.