Ọrịa shuga na ihe niile gbasara ya > Ọgwụgwọ na mgbochi

Mgbe nchịkwa intravenous nke 200 mg nke alfa-lipoic (thioctic) acid, plasma ịta kachasị (Cmax) bụ 7.3 μg / ml, oge iji ruo ntinye uche kachasị (TCmax) bụ 19 min, na mpaghara dị n'okpuru oge ịta (AUC) bụ 2.2 μg / ml / awa. Mgbe nchịkwa intractic acid dị na 600 mg, Cmax bụ 31.7 μg / ml, TCmax - 16 min, na AUC - 2.2 μg / ml / awa.
Thicctic acid na-enwe “ụzọ izizi” sitere na imeju. Guzobe metabolites na - aputa ihe n'ihi nsị oxidation na conjugation n'akụkụ. Nkeji ọkara bụ nkeji iri abụọ na ise. Ọ bụ ya mere akụrụ, 80-90%, ọkachasị n'ụdị metabolites.

Ofzọ nke ngwa

Ọgwụ Tiogamma TurboN’inwebu ngwakọta na 50-250 ml nke 0.9% sodium chloride ngwọta, a na-agbanye ha n’ime anụ ahụ, nwayọ, ọ bụghị ihe karịrị 50 mg kwa 1 nkeji, na dose 600 mg (1 ampoule) kwa ụbọchị, maka izu 2-4 kwa ụbọchị.
N'ihi mmetụta nke ihe na-arụ ọrụ na ọkụ, ekwesịrị iwepụ ampoules n'ime igbe ozugbo tupu nchịkwa. E kwesịrị ichebe ihe dị n’ịchịkọta ihe n’ọkụ.

Nsonaazụ

Mgbe ị na-eji ọgwụ ọjọọ eme ihe Tiogamma Turbo mmetụta ndị enwere ike dị ka: usoro mmeghachi omume nfụkasị ahụ, ruo na mmepe nke anaphylactic ujo, urticaria ma ọ bụ eczema na ntụtụ ebe, ọnya ọgbụgba ọbara (purpura), thrombophlebitis, ọgbụgbọ, ịchafụ, isi ọwụwa na ọgba aghara nke anya n'ihi mbelata shuga ọbara, ubara mgbali intracranial na dyspnea nwere nchịkwa intravenous ngwa ngwa, ọgbụgbọ, ọgbụgbọ, mgbu afọ, afọ ọsịsa.
Ọ na-adịkarị: ụtọ nri.

Contraindications:
Ihe mgbochi igbochi iji ogwu Tiogamma Turbo bụ: hypersensitivity na mmiri ọgwụ, gastric ulcer, hyperacid gastritis, jaundice siri ike nke etiology, decompensated ụdị ọrịa shuga, ime na lactation, nwata na etolite ruo 18.

Mmekọrịta na ọgwụ ndị ọzọ

Enwere mbelata na arụ ọrụ nke cisplatin mgbe ejiri ya mee ihe n'otu oge Tiogamma Turbo. Ekwenyeghi ọgwụ a n’otu oge, ya na iron, magnesium, potassium, oge etiti oge n’etiti usoro ọgwụ ndị a kwesịrị ịbụ ma ọ dịkarịa ala 5 awa. Ebe ọ bụ na enwere ike ịbawanye ike ịbawanye ike nke insulin ma ọ bụ ihe ndị na-egbu egbu nke ọgwụ, a na-atụ aro ka a na-atụle shuga ọbara kwa ụbọchị, karịsịa na mmalite ọgwụgwọ na Tiogammma. Iji zere ihe mgbaàmà hypoglycemia
Ọ dị mkpa iji nlezianya nyochaa ọkwa nke glucose dị n'ọbara.

Dodoụbiga ya ókè

Mgbaàmà nke egbu egbu egbu Tiogamma Turbo (ihe karịrị 6000 mg na okenye ma ọ bụ karịa 50 mg kwa kilogram nke ịdị arọ nwatakịrị): ihe ọdịdọ juputara na nkwarụ, oke nsogbu nke acid-base balance na-eduga na lactic acidosis, ọgba aghara siri ike na coagulation ọbara.
Ọgwụ:: ụlọ ọgwụ ozugbo na usoro ọgwụgwọ ọ bụla maka ịpụ mmadụ (ntopute ọgbụgba, ọgbụgba na unyi). Ọgwụ ọgwụgwọ bụ Symptomatic, enweghị ọgwụ mgbochi akọwapụtara.

Mpempe mwepụta

Na-echebara echiche maka ngwọta maka infusion, 30 mg / ml
A na-etinye 20 ml nke ọgwụ ahụ na ampoules nke iko aja aja.
A na-etinye ampoules ise n'ime kaadiboodu.

20 ml nke ihe ngwọtaTiogamma Turbo nwere ihe dị n’ime - acid thioctic meglumine nnu - 1167.70 mg (nke ya na 600 mg thioctic acid).
Ndị ọkachamara: meglumine, macrogol 300, mmiri maka ịgba ntụtụ.

Nhọrọ

:
N'oge ọgwụgwọ ọgwụ Tiogamma Turbo a ofụbiga mmanya ókè.
Akụkụ nke mmetụta na ikike ịnya ụgbọ ala na usoro ndị nwere ike ịdị ize ndụ
Nwee mmetụta ndị ọzọ, a ga-elezi anya mgbe ị na-anya ụgbọ ala na igwe nwere ike ịdị ize ndụ.

Weputara udi ya na ihe mebere ya

Biconvex, etinye ya na blisters cellular (10 pcs.). Otu mkpọ nwere blisters 10, 6 ma ọ bụ 3. Na 1 granule bụ 0.6 g nke thioctic acid. Ihe ndi ozo:

sodium croscarmellose
cellulose (na microcrystals),
sodium lauryl sulfate,
macrogol 6000,
stereta magnesium,
simethicone
hypromellose,
lactose monohydrate,
iteghete E171.

Ọgwụ Tiogamma dị n'ụdị mbadamba, ampoules na ngwọta.

Erere na karama iko. N ’ngwugwu 1 dị na ampoules 1 ruo 10. 1 ml nke infusion solution nwere 12 mg nke ihe na-arụ ọrụ (thioctic acid). Ihe ndi ozo:

mmiri mgbochi
meglumine
macrogol 300.

Omume ọgwụ

Akụkụ ike nke ọgwụ ahụ bụ ọgwụ antioxidant dị irè nke nwere ike ịchikọta radicals n'efu. A na-agwakọta Alfa lipoic acid n’ime ahụ n’oge decarboxylation nke alpha keto acid.

na-abawanye glycogen etoju,
na-ebelata glucose ọbara
na-egbochi nguzogide insulin.

Dabere na ụkpụrụ nke mkpughe, akụkụ akụrụngwa ọgwụ a na-arụ ọrụ yiri Atiya B.

Ọ na-ahụ maka metabolism nke lipids na carbohydrates, na-eme ka imeju ahụ dịkwuo ike ma mee ka metabolism dịkwuo ala. Ọgwụ nwere:

hepatoprotective
hypoglycemic,
hypocholesterolemic,
Mmetụta egbugbere ọnụ.

Na - emekwa ka ihe oriri dị mma nke akwara dị mma.

Ihe ngbanwe

Nkwekọrita zuru oke gụnyere:

enweghi lactase,
tụụrụ ime
ụdị ịhoụbiga mmanya ókè
mgbochi galactose
inye ara
galactose-glucose malabsorption,
afọ ruo afọ 18
mmadu anabataghi ya maka ihe mejuputara ogwu ahu.

Chronic formụbiga ihe ọ chronicụ chronicụ na-egbu egbu bụ ihe mgbochi megide iji ọgwụ Tiogamma.
Ihe ọgwụ Tiogamma dị n’oge ime dị ime.
U nwa bụ otu n’ime ihe ndị metụtara igbochi ọgwụ Tiogamma.

Etu ị ga-esi

A na-ahazi azịza ya etu (iv). Nkezi nha kwa ụbọchị bụ 600 mg. A na-enye ọgwụ ahụ n'etiti ọkara otu elekere site na iji eji.

Mgbe ị na-ewepụ karama ahụ na ọgwụ ahụ n'ime igbe ahụ, a na-etinye ya ozugbo n'ọnọdụ pụrụ iche iji chebe ya pụọ n'ọkụ.

Oge ọ na-eji ọgwụ eme ihe sitere na izu abụọ ruo izu anọ. Ọ bụrụ n ’usoro nlekọta na-aga n’ihu, ọ bụ onye ọrịa ka ọ ka enyere ọgwụ.

Na-a drugụ ọgwụ maka ọrịa shuga

Na ọgwụgwọ ọrịa shuga mellitus, ihe na-arụ ọrụ nke ọgwụ ahụ na-eme ka mgbasa nke endoneural ma na-abawanye mmepụta nke glutathione, na-eme ka ọrụ nke akwara endings dịkwuo mma. Maka ndị ọrịa mamịrị, a na-ahọpụta usoro nke ọgwụ n’otu n’otu. N'otu oge, ha na-enyocha ọkwa nke glucose ma, ọ bụrụ na ọ dị mkpa, họrọ usoro insulin.

Na-arịa ọrịa shuga, a na-ahọpụta usoro ọgwụ Tiogamma n'otu n'otu.

Ngwa di na cosmetology

A na-ejikarị Thioctic acid n'ọhịa nke cosmetology. Site n'enyemaka ya, ị nwere ike:

ezigbo ihu ihu,
belata uche nke anụ ahụ,
kpochapu ihe otutu (achoputan),
gwọọ ọnya
warara pores nke anụ ahụ nke ihu.

A na-eji Tiogamma eme ihe n'ọbara nke cosmetology.

Site na usoro ahụ ji alụso ọrịa ọgụ

systemic allergies
anaphylaxis (nke a na-adịghị ahụkebe).

ọzịza
itching
urticaria.

Mgbe ị na-eji ọgwụ ahụ Tiogamma, mmeghachi omume nfụkasị n'ụdị itching ga-ekwe omume.

Mmekọrịta na ọgwụ ndị ọzọ

Site na ngwakọta nke alfa-lipoic acid na cisplatin, ịdị irè ya na-ebelata yana nchịkọta nke akụkụ ndị na-arụ ọrụ na-agbanwe. Ihe na-arụ ọrụ nke ọgwụ ahụ na-ejikọ iron na magnesium, yabụ, a ga-ejikọrịrị ya na ọgwụ ndị nwere ihe ndị a.

Mgbe ị na-ejikọ mbadamba nkume na hypoglycemic na insulin, mmetụta ọgwụ ha na-abawanye nke ukwuu.

Enwere ike dochie ọgwụ a:

Lipoic acid
Thioctacid BV,
Berlition 300,
Tiolepta Turbo.

Alpha-lipoic (thioctic) acid maka ọrịa shuga mellitus Ihe ịrịba ama nke ọrịa shuga na ụmụ nwanyị

Dọkịta Mma

Ivan Korenin, 50 afọ, ogbunigwe

Actionrụ ọrụ antioxidant dị irè. Gosiputa uru ya bara. Ọ na - eme ka akpụkpọ ahụ na ọdịmma gị dịkwuo mma. Isi ihe bụ soro ntuziaka ahụ, mgbe ahụ agaghị enwe “mmetụta ọ bụla”.

Tamara Bogulnikova, 42 afọ, Novorossiysk

Ezigbo ọgwụ dị mma maka ndị nwere arịa ụgbọ mmiri "ọjọọ" na ndị chọrọ ifelata. A na-ahụ ọgwụ nje a na-akpọ akpọ n'ụbọchị mbụ. Nsonaazụ ndị a na-adịghị ahụkebe na-esitekarị na ọrụ sistemụ akwara na akụkụ ụjọ.

Sergey Tatarintsev, gbara afọ 48, Voronezh

Anọ m arịa ọrịa shuga ogologo oge. N'oge na-adịbeghị anya, ahụ erughị ala malitere ịpụta n'ụkwụ. Dọkịta tiri ọgwụ maka ọgwụ a. N'oge gboo, ọ gbara ọgwụ injection, mgbe ahụ, dọkịta zigara m ọgwụ. Ihe ịrịba ama ndị na-adịghị mma apụwo n'anya, na ike gwụkwaala ụkwụ ugbu a. Anọgide m na-a medicationụ ọgwụ maka mgbochi.

Veronika Kobeleva, gbara afọ 45, Lipetsk

Nne nne nwere ọrịa mellitus (ụdị 2). Ọnwa ole na ole gara aga, a malitere iwepụ ụkwụ ya. Iji mee ka ọnọdụ ahụ ka mma, dọkịta depụtara ihe ngwọta a maka infusion. Ọnọdụ onye ikwu ahụ kawanye mma. Ugbu a ya onwe ya nwere ike ịga n'ụlọ ahịa. Anyị ga-anọgide na-agwọ anyị.

Ihe ngosi maka ojiji

Edere Thiogamma maka ọgwụgwọ nke:

akwara mmebi na-arịa ọrịa shuga
ọrịa imeju
Mbibi nke mmanya akwara na ndabere nke ị dependụbiga mmanya,
nsi
polyneuropathy ihu na sensọ-moto.

Ọgwụ dị n'ụdị nke ọgwụ endogenous, nke na ọkwa cellular na-etinye abụba na metabolism metabolism.

Ntụziaka maka ojiji

A na-emezi Thiogamma intravenly ruo nkeji iri atọ, ọ bụghị ihe karịrị 1.7 ml kwa nkeji. Dabere na ntuziaka maka ojiji, ọ dị mkpa ịgwakọta ọdịnaya nke 1 ampoule na 50-20 ml nke 0.9% sodium chloride solution, wee kpuchie ya na okwu nchebe anwụ. Jiri n'ime awa 6.

A na - ewepụ ihe ngwọta Tiogamma nke akwadoro maka ndị na - eji mmiri eme ihe na ngwugwu, kpuchie ya na ikpe nche anwụ. Na infusion a rụrụ site na kalama. Usoro ahụ bụ izu 2-4 (n'ọdịnihu, dọkịta nwere ike ịkọwa ọgwụ).

Igbe nke mbadamba Tiogamma nwere ntuziaka maka ojiji. Jiri afọ efu na-enweghị ihe ọ ,ụ ,ụ, na-a drinkingụ mmiri ọ .ụ .ụ. Dosebọchị kwa ụbọchị bụ 1 mbadamba. Ọgwụgwọ ahụ dị ụbọchị 30-60. A na-anabata usoro ọmụmụ ugboro ugboro ka ọnwa 1.5-2 gachara.

Njirimara ngwa

Ọ kwesịrị ịchịkwa ọkwa nke glucose dị n'ọbara, mezie dose nke insulin na ọgwụ ndị ọzọ. Otu achịcha achịcha nke mbadamba 1 erughị 0.0041.

Thiogamma na mmanya na-ekwekọ ekwekọ. Amachibidoro ị toụ mmanya n'oge ọgwụgwọ. Ma ọ bụghị ya, ọgwụgwọ ọgwụgwọ na-ebelata, neuropathy na-etolite ma na-aga n'ihu.

N'oge ọgwụgwọ, a na-ahapụ ya ka ọ kwakọba ụgbọala na usoro ndị dị ize ndụ, ebe ọ bụ na emebighị ọhụụ na nlebara anya.

Amachibidoro itinye Tiogamma n'ahụ ụmụ nwanyị dị ime na n'oge a na-enye nwa ara. E nwere ihe ọghọm nke inye nwa ahụ nsogbu. Ọ bụrụ na ọ gaghị ekwe omume ịkagbu ọgwụ n'oge a na-enye nwa ara, a na-akwụsị ịctụ ara.

Notmụaka na ndị nọ n'afọ iri na asatọ na-erubeghị 18 edeghị Thiogamm, ebe ọ bụ na thioctic acid na-emetụta metabolism.

Edere ọgwụ a maka oke ibu, mana ọ dabere na ọnụnọ mmega ahụ na obere kalori.

Na nwata

Amachibidoro ọgwụ a iji maka afọ 18. Nke a bụ n'ihi mmụba nke thioctic acid na metabolism, nke nwere ike ibute nsonaazụ na-achịkwa ahụ n'ahụ ụmụaka na ụmụaka. Tupu ojiji, ịkwesịrị ịgakwuru dọkịta mgbe niile ma nweta ikike mgbe nyochachara akụkụ ahụ na sistemụ nyocha nke ọma.

Nkwado ọgwụ ka akwadoro iji eme ihe gbasara ụmụaka, ebe nsonaazụ dị egwu nwere ike ịmalite n'ụdị nsonaazụ, nke na-esiri ụmụaka ike ịkwụsị.

Njirimara nke ọgwụ a

Thiogamma bụ ngwá ọrụ na-enyere aka ịgbatị usoro metabolic. Mba nke sitere na ọgwụ a bụ Germany. A na-emepụta ya n'ụdị:

ọgwụ
infusion ngwọta (na droppers),
tinye uche maka imepụta ihe ngwakọta (ọ bụ ampoule ka a na-eme).

Mbadamba ahụ nwere ihe bụ isi - thioctic acid, na ngwọta nke infusion - nnu meglumine nke thioctic acid, na itinye uche maka infusions nke meglumine. Na mgbakwunye, ụdị ọgwụ ọ bụla nwere ihe enyemaka dị iche iche.

Thioctic acid (aha nke abụọ bụ alfa lipoic) bụ ọgwụ antioxidant kekọta ahụ. Ọ na-ebelata shuga dị n'ọbara ma na-eme ka ogo nke glycogen nwee ike na imeju, nke, n'aka nke ya, na-emeri iguzogide insulin. Na mgbakwunye, thioctic acid na-edozi metabolism nke lipids, carbohydrates na cholesterol. Ọ na - eme ka ọrụ akwara dị ọcha na neurons trophic, belata ahụ nsí. Na mkpokọta, alpha lipoic acid nwere mmetụta ndị a:

hepatoprotective
iweda ike
hypocholesterolemic,
hypoglycemic.

Na ọgwụgwọ ọrịa shuga, alfa-lipoic acid na-eme ka ọbara na -akpata ọrịa endoneural, na-abawanye ọkwa nke glutathione, n'ihi ya, enwere ọganihu na ọrụ nke eriri akwara.

A na-eji acid Thioctic acid mee ihe maka ebumnuche ịchọ mma: ọ na-ebelata ihu ihu, na-ebelata akpụkpọ ahụ, na-agwọ ọnya, yana metụtara ọnya, na-egbochi pores.

Ahịa na nyocha ọgwụ

Ọnụ ego ọgwụ ọjọọ ahụ na-adabere n'ụdị ntọhapụ ya. Yabụ, ọnụahịa nke mbadamba (30 iberibe 600 mg) dịgasị iche site na 850 ruo 960 rubles. Ọnụ ego nke ihe ngwọta maka infusion (otu karama) bụ site na 195 ruo 240 rubles, ihe mejupụtara maka infusion ciki dị ihe dị ka 230 rubles. Nwere ike ịzụta ọgwụ n’ihe fọrọ nke nta ka ọ bụrụ ụlọ ahịa ọ bụla.

Nyocha ndị dọkịta na ndị ọrịa banyere ọgwụ Tiogamma dị mma. Ogwu a kacha mara amara n’inye shuga na igbochi neuropathy. Ọtụtụ ndị dọkịta na-arụ ụka na ị kwesịghị ịtụ egwu nnukwu ndepụta nke contraindications na mmetụta ndị ọzọ. N'ezie, mmeghachi omume na-adịghị mma na-ewerekarị obere oge - oge 1 na 10,000.

N'izo aka na nyocha ndi ahia nke ngwa a, enwere ike igha uru ndi a:

iji mbadamba ụrọ, naanị otu ugboro kwa ụbọchị,
amụma ọnụahịa
obere usoro ọgwụgwọ.

Ndị dọkịta na-edekarị ọgwụ Tiogamma ọgwụ n'ụdị ihe ngwọta maka infusion n'okpuru ọnọdụ ụlọ. Ọgwụ nwere ngwa ọgwụgwọ ngwa ngwa ma ihe fọrọ nke nta anaghị akpata nsonaazụ.

A na-ahụta Thiogamma dị ka ngwaahịa ịchọ mma. Imirikiti ndị ọrịa na-ekwu na ọgwụ ahụ na-anagide wrinkles n'ezie.

Mana n'ọnọdụ ụfọdụ, mmeghachi omume nfụkasị ahụ dịka redness na itching ga-ekwe omume.

Ndepụta ọgwụ ndị yiri ya

Ọ bụrụ na onye ọrịa anabataghị ọgwụ a ma ọ bụ nwee nsonaazụ ya, a ga-akwụsị ị theụ ọgwụ ahụ.

Dọkịta nwere ike inye gị ọgwụ ọzọ yiri ya nke ga-enwe thioctic acid, dịka ọmụmaatụ:

A na-ejikarị Thioctacid na ọgwụgwọ nke akara nke neuropathy ma ọ bụ polyneuropathy n'ụdị ịhoụbiga mmanya ókè na ọrịa shuga. A tọhapụrụ ọgwụ ahụ n'ụdị mbadamba ma tinye uche.N'adịghị ka Tiogamma, Thioctacid nwere ọgwụ mgbochi dị obere, nke na-agụnye naanị oge mmegharị, inye nwa, nwata na ntinye nke ọgwụ ahụ. Costgwọ ọgwụ dị n'ụdị mbadamba ihe dị ka 1805 rubles, ampoules maka infusion nke ime - 1530 rubles.
Berlition nwere mmetụta dị mma n'ahụ ahụ mmadụ, ebe ọ na-eme ka metabolism na-eme ngwa ngwa, na-enyere aka inweta vitamin na nri, na-eme ka metabolism na abụba metabolism na-arụ ọrụ nke ọma na-arụ ọrụ nke ngwugwu neurovascular. A na-ahapụ ọgwụ ahụ n'ụdị ampoules na mbadamba. Ọnụ ego ampoules dị 570 rubles, mbadamba - 765 rubles.
Lipothioxone bụ ihe ngbochu maka ngwakọta infusion eji ya na polyneuropathy na-arịa ọrịa shuga na mmanya. Enweghi ike iji ya maka ụmụaka gbara afọ 6, yana n’oge ime, a na-anabata iji ọgwụ ahụ ma ọ bụrụ na ọgwụgwọ ahụ gafere ihe ize ndụ nke nwa ebu n’afọ. Ọnụ ego ọgwụ a bụ 464 rubles.
Oktolipen - ọgwụ a na - eji egbochi insulin na - eguzogide ọgwụ, shuga dị elu ma na - eme ka glycogen nwee umeji. O nwere ogwu n ’udiri mbadamba ihe, kapusulu ma tinye uche ya maka osisa ya. Ọnụ ego ọgwụ a na - akwụ ụgwọ bụ capsules 315 rubles, na mbadamba - 658 rubles, na ampoules - 393 rubles. Oktolipen dị ụdị ọrịa mellitus nke 2 nwere ike ijikọ nke ọma na metformin na ndị ọzọ hypoglycemic.

Dabere na contraindications na ohere nke ego, a na-enye onye ọrịa ohere ịhọrọ nhọrọ kachasị mma nke ga-enwe mmetụta ọgwụgwọ dị mma.

Yabụ, Thiogamma bụ ọgwụ dị irè n'ịgwọ ọrịa neuropathy mamịrị na ọrịa ndị ọzọ siri ike. Ngwakọta ya na-arụ ọrụ, thioctic acid, na-emetụta metabolism nke abụba na carbohydrates, na-ebelata ọkwa nke glucose n'ọbara, na-eme ka ihe glycogen dị na imeju na -echepụta akwara anụ ahụ na insulin. Ọgwụ dị n'ọtụtụ ụzọ. Mgbe ị na-a drugụ ọgwụ a, ị ga-agbaso ndụmọdụ dọkịta, ebe ọ bụ na n'ọnọdụ ụfọdụ, mmeghachi omume na-adịghị mma. N'ụzọ bụ isi, a na-aza ngwa ahụ nke ọma, yabụ enwere ike iji ya mee ihe ọ bụla iji mee ka usoro ụjọ ahụ kwụsị ịrụ ọrụ.

A kọwara uru nke lipoic acid maka ọrịa shuga na vidiyo n'isiokwu a.

Omume ọgwụ

Ngwakọta kachasị dị na nkwadebe ọgwụ Tiogamma, n'agbanyeghị ụdị ntọhapụ, bụ thiocticma obu alfa lipoic acid (aha abụọ nke otu ihe arụ ọrụ na-arụ ọrụ). Nke a bụ akụkụ ebumpụta ụwa nke metabolism, ya bụ, a na-abụkarị acid a bụ ahụ na arụ ọrụ dịka coenzyme nke ogige mitochondrial ike metabolism nke pyruvic acid na alfa-keto acid n'okporo ụzọ oxarative decarboxylation. Thioctic acid dịkwa endogenous. antioxidant, ebe o nwere ike ekekọta radical n'efu ma chebe sel pụọ na mmetụta mbibi ha n'ụzọ dị otu a.

Ọrụ nke akụrụngwa nke ọgwụ ahụ dịkwa mkpa carbohydrate metabolism. Ọ na - enyere aka belata glucose na ọbara ọbara yana mkpokọta nke glycogen na sel imeju. N'ihi ihe onwunwe a, thioctic acid na-ebelata nguzogide insulin mkpụrụ ndụ, nke ahụ bụ, azịza physiological maka homonụ a na - arụ ọrụ karịa.

So na ụkpụrụ nke metabolism metabolism. Mmetụta nke ihe na-arụ ọrụ na metabolism bụ nke a na-ahụkarị. cholesterol dị ka onye na-ahụ maka hypocholesterolemic, acid na-ebelata mgbasa nke obere lipids dị ala na pasent nke njupụta dị elu na ọbara na-abawanye). Nke ahụ bụ, acid thioctic nwere ụfọdụ ihe antiatherogenic ma na-asachapụ akwa nke maịkwa na macrocirculatory nke oke abụba.

Mmetụta detoxification A na-ahụta nkwadebe ọgwụ ọgwụ n’ihe banyere mmerụ ahụ nwere nnukwu ọla nnu na ụdị ndị ọzọ mmenaanya. Omume a na - ebido n'ihi mmegharị usoro n'ime imeju, n'ihi na ọrụ ya na-aka mma. Agbanyeghị, ọgwụ thioctic acid adịghị enye aka na ike ọgwụgwụ nke anụ ahụ nwere, yana oke ya na-enwe ike Ngwongwo hepatoprotective.

O kwesiri iburu n’uche na ogwu eji alfa-lipoic acid eme ihe maka ya oria shuga, ebe ọ bụ na ndị mejupụtara aka na-enyere aka belata nguzobe nke metabolites metabolites ma mụbaa ọdịnaya ihe oriri ka physiologically nkịtị egosi. Ọzọkwa trophic akwara mma na ọbara ọgbụgba azụ, nke na-eduga n'ọbara ọkwa tozuru oke na steeti akwara akwara ma gbochie mmepe nke ọrịa mamịrị. polyneuropathy (akụkụ nosological na-etolite n'ihi mbibi nke ogwe akwara site na ịba ụba nke glucose na metabolites ya).

Ngwongwo ogwu ya (hepato- na neuroprotective, detoxification, antioxidant, hypoglycemic and many other) thioctic acid yiri vitaminOtu B.

Thioctic ma ọ bụ alfa lipoic acid enwetawo ewu ewu na ihe ịchọ mman'ihi ihe ndị a na-arụ na ọgwụ ndị a akpukpo aru, nke na-esikarị ike ilekọta:

na-ewepụ hypersensitivity,
na-emechi akpụkpọ ahụ na-ebelata ịdị omimina-eme ka a ghara ịhụ ha anya ọbụna n'akụkụ siri ike dịka nkuku nke anya na egbugbere ọnụ,
gwọọkwa akara si ihe otutu (ihe otutu) na isi, ebe ọ bụ, na-abanye n’ime ihe dị n’ime ala ahụ, ọ na-akpali ọrụ nkịtị nke usoro inyeghachi ihe,
na-eme pores na ihu ma na-edozi ikike ịrụ ọrụ glandssi otú a mee ka nsogbu nke mmanụ ma ọ bụ nke nwere mmanụ maa mma.
na - eme dị ka ọgwụ antioxidant dị egwu nke sitere na endogenous.

Pharmacodynamics na pharmacokinetics

Na nchịkwa ọnụ ọgwụ a na-agbatị ngwa ngwa ma zuo ezu site na eriri afọ. Ọ kwesiri iburu n’obi na iji ọgwụ a n’otu oge were nri na-ebelata mmụba nke Thiogamma. Mgbe uzo mbu gachara site na imeju, ihe di omimi nke mejuputara nke oma gabigara mgbanwe n’enweghi mgbanwe (na akwukwo nke ogwu ogwu a ka akowara ya dika mmetụta mbu nga), n'ihi na bioavailability nke ọgwụ sitere na 30 ruo 60 pasent, dabere na ikike metabolic nke ahụ. Oke kachasị nke plasma bụ ihe 4 μg / ml nwere oge nnyefe nke nkeji iri atọ.

Thiogamma maka ụmụ eji atụfu mmiri ma ọ bụ nkwadebe nke ọgwụ infusion na-achịkwa intravenously, ya mere, nkwadebe ọgwụ ọgwụ n'ụdị ntọhapụ na-ejikwa iji zere nsonaazụ nke akụkụ mbụ. Oge nnyefe n'ime sistemụ sistemụ bụ ihe dị ka nkeji iri nke 10-11, na ntinye plasma kachasị na nke a bụ 20 μg / ml.

Metabolized ọgwụ, n'agbanyeghị ụdị eji,na imeju site na iji ajị anụ eme ụdọ na ngbanwe ọzọ. Mkpochapụ plasma - 10-15 ml / min. Thioctic acid na ngwaahịa metabolic ya egosirinke ka nke akụrụ(ihe dị ka pasent 80-90). N'ime mmamịrị ahụ, a na-ahụ ntakịrị ihe ndị na - agbanweghi agbanwe nke nkwadebe ọgwụ. Ndụ ọkara nke ọgwụ Tiogamma 600 (ọnụọgụ 600 na-egosi oke nke alfa-lipoic acid n'ihe banyere okpukpo akọrọ) bụ minit 25, yana ụdị ọgwụ a na-akwalite. Tiogamma Turbo - site na minit 10 ruo 20.

Thiogamma, ntuziaka maka ojiji (Usoro na usoro onunu ogwu)

Ntuziaka maka ojiji Thiogamma dịgasị iche dabere n'ụdị ọgwụ ọgwụ ejiri.

Mpempe 600 mg etinyere ọnụ ọnụ otu ugboro n'ụbọchị. Ejila ha ata, ebe ọ bụ na shei ahụ nwere ike imebi, ọ na-atụ aro ị drinkụ ya na ntakịrị mmiri. Ọ bụ dibịa na-eleta ka enyere iwu oge agụmakwụkwọ ahụ n'otu n'otu, n'ihi na ọ dabere na ogo ọrịa ahụ. A na-ewere mbadamba ụbọ site na ụbọchị iri atọ ruo iri isii. Ighaghagharia nke usoro ọgwụgwọ na - ekwe omume ugboro abụọ n'afọ.

Tiogamma Turbo ejiri maka nchịkwa parenteral site na intravenous drip infusion. Usoro ubochi kwa ubochi bu 600 mg 1 kwa ubochi - gbakotara ihe di n’ime otu karama ma obu ampoule. A ga-eme iwebata nwayọ nwayọ nwayọ, ihe karịrị nkeji iri abụọ ruo iri abụọ na asaa iji wee gbochie nsonaazụ ya site na ngwa ngwa ọgwụ a. Usoro ọgwụgwọ ụdị ọgwụ a sitere na izu abụọ ruo izu anọ (mkpirisi mkpirisi ọgwụgwọ a na-akpata ya bụ n'ihi oke ọkwa plasma kachasị mma mgbe nchịkwa ọgwụ ahụ gachara.

Tụkwasịnụ maka nkwadebe nke intus eji eme ihe dị ka ndị a: ihe dị n'ime 1 ampoule (na usoro nke isi ihe na - arụ ọrụ - 600 mg nke thioctic acid) bụ ngwakọta 50ot50 isotonic (pasent 0.9) sodium chloride. Ozugbo ịkwadebe ngwakọta ọgwụgwọ, kpuchie karama ahụ na ikpe nchekwa na-enwu enwu (enweghị ọdịda, enwere otu ikpe kwa ngwungwu ọgwụ dị na ngwugwu ọgwụ ahụ). Ozugbo, a na-ahụzi azịza ya site na irighiri irighiri akwara dị n'ime nkeji 20-30. Oge nchekwa kachasị nke usoro Tiogamma dị njikere adịghị karịa awa 6.

Enwere ike iji Thiogamma maka nlekọta anụ ahụ ihu. Iji mee nke a, tinye mpempe ọgwụ maka ndị na-atụpu ya na vials (ampoules na itinye uche maka nkwadebe nke infusions intravenous adịghị mma dị ka ngwaahịa ịchọ mma, n'ihi na ha nwere ike ibute mmeghachi omume nfụkasị n'ihi nnukwu akụkụ nke arụ ọrụ). A na-etinye ihe dị n’ime otu karama ahụ n’ụzọ dị ọcha n’akpụkpọ ahụ dum ugboro abụọ n’ụbọchị - n'ụtụtụ na mgbede. Tupu njakịrị dị otú ahụ, a na-atụ aro iji mmiri dị ncha, ncha dị ọcha iji sachaa ọnụ ụzọ mbata nke pores maka ịbanye n'ime thioctic acid miri emi.

Ntụziaka pụrụ iche

Enwere ike iji nkwadebe ọgwụ na-emepụta ọgwụ dị ka ihe ịchọ mma iji lekọta akpụkpọ nke ihu. Ngwa ndị nọ n'ọrụ nwere ikike antioxidant dị ike na enweghị mmetụta tonic siri ike, n'ihi na Thiogamma maka ihu enwetawo nnukwu aha ewu ewu na cosmetology cosmatology dị ka tonic na-ebuli elu. Enwere ike iji Thiogamma maka akpụkpọ ahụ peape na ntuziaka maka ọgwụ.

Iji ọgwụgwọ a ọgwụ anaghị emetụta ikike itinye uche ma ọ bụ ogologo oge iji nlezianya na-elebara anya, ya mere ịkwọ ụgbọ ala ma ọ bụ na-arụ ọrụ na usoro ndị ọzọ dị egwu nke nwere ike ibute ndụ ndụ n'oge amachibidoro ịgwọ ọrịa.

Analogs nke Thiogamma

Anaatrik Thiogamma mejuputara otutu ndi ogwu, kama n'ihi na ogwugwo onwonye a na acho ugbu a. Ọ dị mfe iji ọgwụ maka igbochi neuropathies siri ike karịa iji usoro nchekwa, mesoo usoro ogologo ọgwụ na-agwụ ike iji mesoo ha mgbe e mesịrị. Ndi eji Tiogamma eme ihe: Ihe oriri 300, Mkpụrụ egbugbere ọnụ Neurona Oktolipen.

Nkwado ọgwụ ka akwadoro iji eme ihe gbasara ụmụaka, ebe nsonaazụ dị egwu nwere ike ịmalite n'ụdị nsonaazụ, nke na-esiri ụmụaka ike ịkwụsị.

Nyocha banyere Tiogamma

Ọgwụ ọgwụ na-ewu ewu na ndị ọrịa na- ọrịa shuga ma ọ bụ amụma ga neuropathy. Ebe ọ bụ na Thiogamma na-enye prophylactic ọgwụgwọ nke ọrịa nke usoro ụjọ ahụ na - enweghị oke maka nkwarụ ahụ ruo ọtụtụ afọ. N'ihi ụzọ dịtụ obere, ị nwere ike ichebe onwe gị pụọ na nsonaazụ dị oke njọ pathology endocrine.

Ndị ji ọgwụ a iche iche na-ekwu na ị kwesịghị ịtụ egwu ọnụọgụ nke nsonaazụ dị iche iche, n'ihi na ogo nke ngosipụta ha, ọbụlagodi dịka ọgwụ ọgwụ nke Healthtù Ahụ Ike Worldwa, na-ahuta dị ka ihe na-adịghị ahụkebe (mmetụta na-adịghị mma nke ọgwụgwọ na-eme n'ihe na-erughị 1/10000 nke ọgwụgwọ mgbanwe. , gụnyere ọdịdọ episodic).

Ndi okacha mara ije ndi dibia na ndi okacha amara n’aru ogwu na-enwe obi uto na Tiogamma, ya mere ha n’eji ya otutu ulo ogwu. N'ihi nsonaazụ nke mbụ, ohere nke ịdoụbiga ihe ókè ma ọ bụ ịba ụba nke ihe ndị na-arụ ọrụ na plasma ọbara na-ebelata, ọ na-esikarị ike ị effectsụ ọgwụ na-akwụsị ngwa ngwa na ngwa ngwa. Na-emegide usoro eziokwu ndị a, Njirimara ọgwụgwọ nke ọgwụ ahụ dị ịtụnanya n'ezie, nke bụ echiche dị mma ọbụlagodi n'etiti ndị ọrụ ụlọ ọgwụ.

Dịka ngwaahịa ịchọ mma, nyocha na Tiogamma na-akwado aha ọgwụ ahụ. Thioctic acid nwere ike ịnagide wrinkles n'akụkụ ndị kachasị sie ike na ihu ma nke a gosipụtara site n'ọtụtụ njedebe maka nzukọ maka nlekọta anụ ahụ. Agbanyeghị, enwere ọnụnọ nke mmeghachi ahụ nfụkasị anụ ahụ na ndị mmadụ na-ebute mmeghachi omume dị otú a (hypersensitivity or hereditary idiosyncrasy), ya mere, a na-atụ aro ka eme nnwale nfụkasị ahụ tupu iji Thiogamma.

Ọnụ ahịa Thiogamma, ebe ị ga-azụ

Ọnụahịa Tiogamma 600 mg na-adabere n'ụdị ntọhapụ nke nkwadebe ọgwụ, ma na Russia ma na Ukraine:

ọgwụ - site na 800 ruo 1000 rubles / 270-300 hryvnia n'otu ngwugwu,
Tiogamma Turbo - 1000-1200 rubles / 540-650 hryvnias,
ampoules nwere parenteral solution - 190 rubles (ọnụ ahịa otu ampoule) / 640-680 hryvnias (ọnụahịa kwa ngwugwu),
mmiri mgbapubu n’obi maka infusion intravenous - 210 rubles (kwa karama) / 72 hryvnias (ọnụ ahịa otu mkpụrụ ọgwụ).

N'oge ime na lactation

N'ihi ọdịnaya nke ihe ndị na-arụ ọrụ n'ime ya, amachibido iji Thiogamma n'oge ime na lactation. Ejikọtara nke a na nnukwu ihe ike ịrụ ọrụ nwa ebu n'afọ yana mmepe nke nwa aka ma ọ bụ nwa amụrụ ọhụrụ. Ọ bụrụ na ọ gaghị ekwe omume ịkagbu ojiji nke ọgwụ n'oge ara, mgbe ahụ ọ dị mkpa ịkwụsị ma ọ bụ kwụsị ị breastụ ara iji zere imerụ nwatakịrị ahụ ahụ́.

N'oge a na-enye nwa ara na ime ime, a machibidoro iji ọgwụ ọjọọ eme ihe n'ihi mmetụta ọ ga-ekwe omume na nwa ahụ.

Mkparịta ụka ọgwụ ọjọọ

Thioctic acid dị ka akụkụ nke Thiogamma na-eme ka mmetụta mgbochi mkpali glucocorticosteroids dị mma. Ihe atụ ndị ọzọ gbasara mmekọrịta nke ọgwụ:

Ngwá ọrụ belata arụmọrụ nke Cisplatin.
Ihe na-arụ ọrụ na-ejikọ ọla, yabụ, a machibidoro iji ígwè, calcium na magnesium n'otu oge - ọ dịkarịa ala awa abụọ ga-agbatịcha n'iji ọgwụ ndị a.
Ọgwụ a na - akwalite ọrụ nke insulin, ọgwụ hypoglycemic nke onọ.
Ethanol nwere metabolites na-ebelata ike nke acid.

Ngwakọta na ụdị ntọhapụ

Thioctic Acid 600mg

Hypromellose, silloon silicon dioxide, celclose microcrystalline, lactose monohydrate, sodium carmellose, talc, simethicone, magnesium stearate, macrogol 6000, sodium lauryl sulfate

Meglumine thioctate (ihe ruru 600 mg nke thioctic acid)

Macrogol 300, meglumine, mmiri

Mbadamba ụrọ Thiogamma

A na-aụ ọgwụ otu ugboro n’ụbọchị tupu nri a na usoro onunu ogwu nke dọkịta nyere, achịkwa mbadamba nkume ndị ahụ agaghị ata ata ma were obere mmiri hichaa ya. Ogologo oge usoro ọgwụgwọ bụ ụbọchị 30-60 ma dabere n'ịgwọ ọrịa ahụ. Ibeghachite usoro ọgwụgwọ nwere ike ịme ugboro abụọ ruo atọ n'afọ.

Thiogamma maka ụmụ eji atụfu mmiri

Mgbe ị na-eji ọgwụ ahụ, ọ dị mkpa icheta ojiji nke ikpe na-echebe ọkụ mgbe ewepụsịrị karama na igbe ahụ. Ekwesịrị imepụta infusion, na-ahụ ọnụego ntụtụ 1.7 ml kwa nkeji.

Site na nchịkwa ọgbụgba, a chọrọ ka ọ nwee nwayọ nwayọ (oge nke 30 nkeji oge), usoro onunu ogwu nke 600 mg kwa ụbọchị. Treatmentzọ ọgwụgwọ a dị izu abụọ ma ọ bụ anọ, mgbe emesịrị ya ka o mee ka nchịkwa nke ọgwụ ahụ ka ọ bụrụ nke mbadamba mkpụrụ osisi n'otu ọgwụ kwa ụbọchị nke 600 mg.

Maka akpụkpọ ahụ

ọrịa mamịrị,
mmanya na-emebi oke akwara,
Ọrịa imeju - ịba ọcha n'anya na ọrịa nke usoro dị iche iche, mmebi nke hepatocytes,
polyneuropathy ihu ma ọ bụ sensọ,
ị withụbiga mmanya ókè nwere ezigbo ngosipụta (dịka ọmụmaatụ, nnu nke ọla ndị dị arọ ma ọ bụ olu).

Ntuziaka maka ojiji Thiogamma dịgasị iche dabere n'ụdị ọgwụ ọgwụ ejiri.

A na-enye mbadamba 600 mg ọnụ otu ugboro n'ụbọchị. Ejila ha ata, ebe ọ bụ na shei ahụ nwere ike imebi, ọ na-atụ aro ị drinkụ ya na ntakịrị mmiri. Ọ bụ dibịa na-eleta ka enyere iwu oge agụmakwụkwọ ahụ n'otu n'otu, n'ihi na ọ dabere na ogo ọrịa ahụ. A na-ewere mbadamba ụbọ site na ụbọchị iri atọ ruo iri isii. Ighaghagharia nke usoro ọgwụgwọ na - ekwe omume ugboro abụọ n'afọ.

A na-eji Thiogamma Turbo mee ihe maka nchịkwa parenteral site na ntinye mmiri nke intravenous. Usoro ubochi kwa ubochi bu 600 mg 1 kwa ubochi - gbakotara ihe di n’ime otu karama ma obu ampoule.

A ga-eme iwebata nwayọ nwayọ nwayọ, ihe karịrị nkeji iri abụọ ruo iri abụọ na asaa iji wee gbochie nsonaazụ ya site na ngwa ngwa ọgwụ a. Usoro ọgwụgwọ ụdị ọgwụ a sitere na izu abụọ ruo izu anọ (mkpirisi mkpirisi ọgwụgwọ a na-akpata ya bụ n'ihi oke ọkwa plasma kachasị mma mgbe nchịkwa ọgwụ ahụ gachara.

A na-eji ntinye uche maka nkwadebe nke infusions intravenous intraven dị ka ndị a: ọdịnaya nke 1 ampoule (na usoro nke isi ihe na - arụ ọrụ - 600 mg nke thioctic acid) bụ ngwakọta 50ot50 isotonic (pasent 0.9) sodium chloride.

Ozugbo ịkwadebe ngwakọta ọgwụgwọ, kpuchie karama ahụ na ikpe nchekwa na-enwu enwu (enweghị ọdịda, enwere otu ikpe kwa ngwungwu ọgwụ dị na ngwugwu ọgwụ ahụ).

Ozugbo, a na-ahụzi azịza ya site na irighiri irighiri akwara dị n'ime nkeji 20-30. Oge nchekwa kachasị nke usoro Tiogamma dị njikere adịghị karịa awa 6.

Ọgwụ bụ ụzọ eji edozi carbohydrate, metabolism metabolism n’ahụ mmadụ.

Kenye ya n'ụdị ndị a:

na arịa ọrịa mamịrị,
ọrịa ọrịa imeju dị iche iche (ụdị ịba ọcha n'anya, ọrịa agagharị, nreba nke hepatocytes),
mmanya na-emebi akwara
egbu egbu nke anụ ahụ, nke iwe dị iche iche na-akpasu iwe, nnu nke ọla ndị dị arọ na ihe ndị ọzọ.

Dị Mkpa! Etinyekwala ọgwụ ị jiri aka gị mee, hụ na ịgakwuru dọkịta tupu ị theụọ ọgwụ ahụ.

Nyocha nyocha Ndidi

Alla, gbara afọ 37. Otu enyi m gwara m ọgwụ a bụ Tiogamma. O weere ya site n'ikike nke dọkịta, mgbe ọ nwesịrị ọzụzụ, na-ejedebeghị onwe ya n'ihe oriri. Amalitere m ịillsụ ọgwụ wee rie nri, maka otu ọnwa kilogram ise funahụrụ m. Ezigbo nsonaazụ, echere m na m ga-emeghachi usoro ahụ ihe karịrị otu ugboro.

Alexey, dị afọ 42. N’ebido n ’ị ofụ mmanya na-egbu egbu, amalitere m polyneuropathy, aka m na-ama jijiji, amalitere m inwe nsogbu mgbanwe mgbanwe ọnọdụ obi ugboro ugboro. Ndị dọkịta kwuru na anyị ga-ebu ụzọ gwọọ ịlisụbiga mmanya ókè, wee kpochapụ nsonaazụ ya. Na ọkwa nke abụọ nke ọgwụgwọ, amalitere m ịgwọ Tiogamma. Ọ nagide nsogbu nke neuropathy, amalitere m ehi ụra nke ọma.

Olga, dị afọ 56 na-arịa ọrịa shuga, yabụ enwere m ọchịchọ ịzụlite neuropathy. Ndị dọkịta depụtara Tiogamma maka prophylaxis, gbakwunyere na-ahazigharị ọgwụ nke insulin. Ana m aillsụ ọgwụ dịka ntuziaka a si dị ma hụ mgbanwe - enwerela m nwayọ karịa, enweghị m nsogbu ọzọ n'abalị na n'ụtụtụ, aka m adịghị ama jijiji site na nchekasị.

Ngwaahịa ọgwụ a ma ama na ndị ọrịa nwere mellitus ọrịa shuga ma ọ bụ nwee ihe ga - eme neuropathies. Ebe ọ bụ na Thiogamma na-enye prophylactic ọgwụgwọ nke ọrịa nke usoro ụjọ ahụ na - enweghị oke maka nkwarụ ahụ ruo ọtụtụ afọ.

N'ihi usoro dịtụ mkpụmkpụ, ị nwere ike ichebe onwe gị pụọ na nnukwu nsonaazụ nke ọrịa endocrine.

Ha na-anabata ọgwụ ahụ n'ọtụtụ ikpe ziri ezi. Obi na-atọ ndị na-arịa ọrịa shuga ụtọ.

Ndị ọkà mmụta sayensị na-ekwusi ike na ị Tụ Tiogamma maka mgbochi abụghị ihe ezi uche dị na ya, mana ya na ngosipụta nke nsogbu na sistemụ akwara, ọgwụ a na-ewetara ndị ọrịa ahụ efe.

Ọmụmụ oge niile na-eme ka ọnọdụ ndị ọrịa dị, mma ndụ ha.