Ọgwụ ọgwụgwọ ọrịa anụmanụ

Hypothyroidism na ụmụ anụmanụ - ọrịa nke ezughi oke ọrụ thyroid nwere ọnọdụ a na-achọpụta ihe gbasara ọrịa, yana edema na bradycardia, metabolism na-emetụta oke ibu, oke isi na ọrịa ndị ọzọ na-arịa ọtụtụ akụkụ na sistem.

Enwere ụdị mkpụrụ ndụ ihe nketa ga - eme ka hypothyroidism, nke gosipụtara site na oge nke pathology n'etiti ụfọdụ ụdị nkịta, ọkachasị, ndị Airedale, ndị na-akụ ọkpọ, ndị na-akpa ọchị, ndị na-anya mmiri, Doberman pinpa, ndị na-ewepụta ọla edo, ndị na-eleba anya na Irish, obere schnauzers Old, ndị ọzụzụ atụrụ Scottish. ya na poodles. Nwamba na-arịa ọrịa obere oge. Nkezi afọ nke anụmanụ na-arịa ọrịa dị afọ 4-10. Bittes na-arịa ọrịa ugboro abụọ 2.5 karịa, ihe ka ukwuu nke ibute ọrịa na ha bụ ihe metụtara mwepu nke akwa.

Enwetara hypothyroidism nke mbu (n'ihe ka ọtụtụ nkịta na-arịa ọrịa) bụ ọrịa lymphocytic thyroiditis (usoro mbufụt na gland, a na-akpọkwa ọrịa Hashimoto) ma ọ bụ idiopathic follicular atrophy (usoro mmebi na gland), nke na-eduga na nsị thyroid na mbelata ọnụ ọgụgụ nke homonụ zoro ezo. Ọtụtụ mgbe, ihe kpatara hypothyroidism na ụmụ anụmanụ bụ enweghị iodine na ntinye nri, mmeri nke gland site na tumo ma ọ bụ usoro nje. Na nwamba, hypothyroidism na-abụkarị ihe na-akpata tayroidectomy ma ọ bụ rediotherapy maka hyperthyroidism.

A na - ejikọ hypothyroidism nke abụọ na mmebi mbụ nke nzuzo nke thyroid na-akpali homonụ (TSH) n'ihi mmekpa ahụ nke ọrịa ọgbụgba ma ọ bụ mbibi nke akụkụ ọgbụgba ahụ site na tumo ma ọ bụ usoro mkpali, nke bụ nsogbu kpatara. A pụkwara imebi mmepụta TSH site na ọgwụgwọ glucocorticoid nke ọrịa concomitant ma ọ bụ nri na-ekwesịghị ekwesị. Homonụ thyroid dị mkpa maka mmepe nkịtị nke akwara na sistemụ akwara etiti, yabụ hypothyroidism nke a na-ahụkarị na cretinism na dwarfism.

Na hypothyroidism, mmebi na-emetụta anụ ahụ, akụkụ ahụ nke exocrine, akwara obi, ụjọ, sistemu endocrine, akwara, akụkụ ahụ, eriri afọ, akụkụ ahụ anya, metabolism na-agbagha. Ihe mgbaàmà nke ọrịa ahụ enweghị atụ ma na-eto nwayọọ nwayọọ.

Ihe ngosiputa mbu nke hypothyroidism bu nkpari, obi uto, anagide mmeme ahu, mgbanwe omume, ubara aru n’enweghi oria, ubara udiri oria, ibelata nke nmeko nwoke na nwanyi, enweghi mmekpa ahu, ikwacha iru ahu n’ihi oke isi.

A na-ahụkarị ọnya anụ ahụ na ndị ọrịa nwere hypothyroidism. Ọ bụ okpomoku, fụrụ akpụ, oyi na-emetụ aka. Seborrhea, hyperpigmentation na hyperkeratosis na-eto. Ekike ahụ na-aghọ nkụ, dull, kenkuwa, thins. Alopeciale abụọ na-acha uhie uhie na-amalite site na ọdụ ("ọdụ ọdụ") ma gbasaa n'ahụ ahụ dum. Mgbanwe ụcha ga-ekwe omume.

Na nyocha dị iche, ọ dị mkpa iwepu ihe ndị ọzọ na-akpata endocrine alopecia, nke ga - ekwe omume na hypercorticism na dermatoses metụtara ọdịnaya dị elu nke homonụ mmekọahụ. Site na hypothyroidism, ọnya na-agwọ adịghị mma na nchikota na-adị mfe, pyoderma na otitis externa na-eme mgbe mgbe. Myxedema na-ekpebi ngosipụta “nhụjuanya” nke ihe egwu ahụ.

A na - egosipụta mmeri nke usoro akwara obi site na bradycardia, pulsation na - adịghị ike ma na - eme ka ike gwụ ike. Site na iji nkuzi ihe omumu, ihe nwere ike ime na myocardial contractility nwere ike ichuta. Na ECG, mbelata nke voltaji ebili mmiri R (

Pathogenesis na mgbanwe mgbanwe ọrịa.

N'okpuru mmetụta nke ihe etiological, njikọta nke thyroxine (T4) na triiodothyronine (T3) na-egbochi n'ime ahụ, nke na-eduga n'ịbawanye uru nke ọkwa nke thyroid na-akpali homonụ (TSH).

Nbelata ogo ọbara nke homonụ thyroid na-akpata mmebi nke metabolism nke carbohydrate, protein, lipid, vitamin and mineral metabolism, nke na-eduga na mgbanwe mgbanwe nke obi, akpa ume, akụrụ, na anụ ahụ.

Mgbanwe akwara na akwara na-egosi mmeju, ịmụba, mbufụt, granulomas na thyroid gland, mgbanwe mgbanwe na akụkụ ahụ ndị ọzọ.

Pathognomonic bụ mmụba dị ukwuu na gland thyroid (goiter).
Akpọnwụ akpọọla nkụ, na -ekwulata ụcha, na-ekpughe ọgba aghara na uto nke ntutu isi (oge na-egbu oge, uto ogologo, isi ike, ntutu na-agbacha agbacha n'oge)
Otu njiri mara nke ọrịa ahụ bụ imebi ọrụ nke akwara obi (bradycardia, ntị chiri, nkewapụ ụda nke obi, belata ọkụ ezé niile na electrocardiogram, ịgbatị oge nke PQ na etiti TQ).
N'ime ụmụ anụmanụ na-arịa ọrịa, mara adịghị mma ahụ, hypothermia, ịda mba, na ịrị elu nke ahụ.
N'ime ọbara, a chọpụtara oligochromia, hypochromia, neutropenia, lymphocytosis, mbelata ọkwa nke T3, T4 na mmụba nke ọdịnaya TSH.

Usoro ya na amụma.

Ọrịa ahụ adịghị ala ala amụma - kpachara anya.

A na-eme nchọpụta nyocha ahụ na-eburu n'uche ọdịnaya iodine dị na nri na mmiri, nyocha ahụike na ahụike yana nyocha ọbara nyocha.

Ọrịa dị iche na mellitus ọrịa shuga, hyperthyroidism, oke ibu, nke ọkwa nke T3, T4, TSH kwekọrọ na ụkpụrụ dị mma.

Ihe kpatara Hypothyroidism na Nkịta na Nwamba

Ọrịa kansa lymphocytic, ọrịa idiopathic atrophy nke gland thyroid, ọrịa congenital, ọrịa pituitary, enweghị iodine na nri, tumor na-akpata na ihe kpatara idiopathic.

Hypothyroidism bụ ihe a na-ahụkarị na nkịta ma ọ na-adịkarị na nwamba. .

Ọ bụ ezie na enweghị ozi amachaghị banyere atụpụta mkpụrụ ndụ ihe ga - eme hypothyroidism na nkịta na nwamba, enwere akụkọ banyere hypothyroidism nke ezinụlọ.

Nkịta dị iche iche ga-arịa ọrịa a: Airedale, onye na-akụ ọkpọ, onye na-achị achị ọchị, Dachshund, Doberman, Onye nkwụghachi ọla edo, nnukwu Dane, onye Irish Setter, obere schnauzer, nkịta onye ọzụzụ atụrụ Bekee ochie, Pomeranian, Poodle Scottish nkịta.

Nkezi afọ mmepe nke ọrịa ahụ bụ afọ 5-8, afọ akara akara bụ 4-10 afọ. Achọpụtabeghị na nwoke na nwanyị inwe mmekọahụ, agbanyeghị, anụmanụ ndị a pịrị apị na-enwekarị ọrịa a.

Pathophysiology nke mmepe nke hypothyroidism n'ime anụmanụ

Enwetara Hypothyroidism nke Mbụ (90% nke nkịta) na-akpata site na lymphocytic thyroiditis (mbufụt nke gland thyroid nke lymphocytes metụtara (50%) ma ọ bụ idiopathic follicular atrophy (50%). A na-ahụ ihe mgbochi ọgwụ megide T3 na T4, a na-ahụ thyroglobulin n'ọbara, agbanyeghị, enwere ike ịchọta otu ọgwụ mgbochi ọrịa nkịtị, anụmanụ euthyroid na pasent dị iche iche (13-40%).

Udiri ihe na - adighi ike akpata hypothyroidism gụnyere - enweghi aidin na nri, na mmebi nke ahuhu site na oria ma obu oria. Hypothyroidism na nwamba, ọrịa ahụ adịghị ala ala, ọ na-abụkarị idiopathic, nke a na-akpata site na mwepụ gland ma ọ bụ ọgwụ radiotherapy na ọgwụgwọ hyperthyroidism.

Ọgwụ hypothyroidism nke abụọ ọ bụ ihe kpatara mmebi nke homonụ na-akwalite homonụ, n'ihi nsonaazụ nke afọ gulitere ma ọ bụ mbibi site na etuto ma ọ bụ ọrịa. Enwetara hypothyroidism nke abụọ nwetara bụ ihe na-adịghị ahụkebe na nkịta na nwamba, yana ọ nwere ike ịbụ nsonazụ nke ọgbụgba na-akpali homonụ ma ọ bụ thyreroropin (TSH), nke nwere ọrụ maka ịkwalite thyroid gland iji mepụta T3 na T4. Glucocorticoids, ọrịa concoitant, erighị ihe na-edozi ahụ na-emebikwa nzuzo nke thyrotropin (TSH). Mgbe ịwachara ọkwa glucocorticoid ọbara, mmepụta TSH na-emekwa ka ọ dị ọcha.

Ọgwụ hypothyroidism n'ihi ihe mgbochi nke hypothalamus Edekọbeghị hotroropin nke na-ewepụta ihe ma ọ bụ thyroliberin na nwamba na nkịta.

Ọkpụkpụ hypothyroidism na-akpata cretinism, ebe ọ bụ na homonụ thyroid dị mkpa maka mmepe nkịtị nke akwara na usoro akwara. Okwu edepụtara na-agụnye enweghị gland thyroid ma ọ bụ mmepe ezughi ezu, ịmepụta homonụ na-ezughị ezu, na ụkọ iodine. A na-ahụkarị hypothyroidism nke abụọ site na nkịta na-azụ atụrụ na-arịa ọrịa phypopituitarism (hypothalamus underdevelopment). A na - ahụta ụkọ nke etolite thyroidropin na-ewepụta homonụ na hypothalamus na risenschnauzer.

Achọpụtara thyroiditis mbufụt na mbufụt nke thyroid gland na ụfọdụ ahịrị nke greyhounds, beagles na nkịta Danish.

Kedu ihe na akụkụ ahụ nke mebiri emebi n'oge hypothyroidism na nkịta

Mgbe m kpọtụrụ onye na-azụ anụ, anụmanụ na-arịa ọrịa nwere mgbaàmà ndị a: ịda mba, nkụda mmụọ, nkụda mmụọ, uru ahụ, ntutu isi na-adịghị mma ma ọ bụ ịkwafu n'ụzọ dị ukwuu, ntutu na-adịghị mma mgbe ịkpụchara ntutu, kpọnwụrụ ntutu ma ọ bụ nke dara ada, isi awọ, ịba ọcha n'anya, ọrịa anụ ahụ ugboro ugboro, ekweghị ibe nọrọ, mmetụta ịhụnanya. Nke ihe iriba ama mbụ dị na mbụ, mmadụ nwekwara ike ịchọpụta ya: ike na-enweghị isi, ịgbanye isi, ahụ mkpọnwụ, ahụ mgbu, infertility. Ihe mgbaàmà nke ọrịa (akara) na-amalite nwayọ, ma jiri nwayọ na-aga.

Site na hypothyroidism na nkịta na nwamba, ọtụtụ sistem ahụ mebiri emebi, ebe ọ bụ na ọrịa ahụ nwere usoro. Enwere ike ihu mgbanwe site na:

Akpukpo aru / nke putara ihe
Ọkpụkpụ akụrụngwa
Usoro ụjọ
Usoro akwara olu
Usoro omumu
Ọkpụkpụ afọ
Anya
Endocrine, usoro homonụ

Oria di iche

Ikpa oke akpukpo aru bu oria akacha bu na nkita nwere hypothyroidism. Ọ dị mkpa ịtụle ihe ndị ọzọ na-akpata isi nkwọcha hormonal (dịka ọmụmaatụ, hyperadrenocorticism, dermatopathy hormone sex, hormone dermatosis, na ndị ọzọ).

Na ọnụnọ nke hyperlipidemia na-ebu ọnụ, nke bụ nchọpụta ụlọ nyocha kachasị na nkịta nwere hypothyroidism, ọrịa ndị na-esochi: ọrịa shuga, hyperadrenocorticism, nephrotic syndrome, nnukwu pancreatitis, mgbochi nke usoro biliary, yana nsogbu metabolism isi.

Ihe kpatara hypothyroidism

Dịka iwu, hypothyroidism na-emetụtakarị nkịta, ọ naghị abụkarị nwamba. Agbanyeghị, n'oge a, emebeghị ka ọ bụrụ na ọ bụ ihe ketara eketa bụ ihe kacha akpata ọrịa a na nkịta. Ka o sina dị, hypothyroidism na-egosikarị n'ụdị ụdị nkịta dị ka:

Onye ọzụzụ atụrụ Scottish
airedale,
poodle
oku okpu
Pomeranian,
Cocker Spaniel
Onye ọzụzụ atụrụ bekee
dachshund
Schnauzer
Doberman
Onye nrụpụta Irish
Nnukwu Dane
Ntughari ọla-edo.

N'ụzọ bụ isi, ọrịa ahụ na-etolite na afọ 5-8 nke ndụ anụmanụ, na afọ ewepụtara afọ bụ 4-10 afọ. Ọrịa ahụ nwere ike imetụta anụmanụ nke nwoke na nwoke. Mana ekwesịrị iburu n'uche na nkịta ma ọ bụ nwamba a na-egbu egbu bụ ihe kachasị emetụta hypothyroidism.

Pathophysiology nke ọmụmụ nke hypothyroidism na nkịta

A na-ahụ hypothyroidism nke mbụ, nke a, inweta, na nkịta 90%. Ọzọkwa, ọrịa lymphocytic thyroiditis, usoro mkpali nke na-eme na ntinye nke lymphocytes na gland thyroid, na-eso akpata ya. A na-ahụ ihe kpatara ya na anụmanụ dị 50%.

A na - eme hypothyroidism enwetara n'ihi nsonathic follicular atrophy na 50% nke nkịta. Nnyocha na-egosi na enwere ọgwụ mgbochi megide T4 na T3 n'ime ọbara anụmanụ. Mana enwere ike achọpụta ụdị ọgwụ mgbochi ọrịa dị na euthyroid, ụmụ anụmanụ nkịtị na 13-40% nke ikpe.

Ihe dị egwu maka ọdịdị nke ọrịa a gụnyere erughi iodine n'ụdị nri na mbibi gland thyroid n'ihi akpụ ahụ ma ọ bụ mmebi ahụ gland site n'ọrịa dị iche iche.

Attentionaa ntị! Na nwamba, hypothyroidism na-abụkarị idiopathic; ọ na - aputa ihe na ikuku ma ọ bụ mgbe ewepụchara gland.

A na - eme hypothyroidism nke abụọ na nkịta n'ihi:

ọrịa na njikọta nke homonụ na-akpali homonụ,
n'ihi ibute ọrịa,
n'ihi ọdịdị nke akpụ na akwara thyroid.

Azọ nke hypothyroidism nwetara nke abụọ abụghị ihe na-ewu ewu na nwamba na nkịta. Ọrịa ahụ nwere ike etolite n'ihi mmebi nke njikọ nke pituitary thyreyropin (TSH) ma ọ bụ homonụ na-akpali akpali, bụ ọrụ maka ịkwalite gland thyroid na synthesize T4 na T3.

Na mgbakwunye, nri nzuzo nke thyrotropin na-egbochi nri na-edozi ahụ, glucocorticoids na ọrịa ndị metụtara. Ya mere, mgbe a na-ahazi ọkwa glucocorticoids, mmepụta nke TSH na-achịkwa.

A hypothyroidism nke obere, nke nwere ike topụta n'ihi igbochi ntọhapụ nke tayrotiberin site na hypothalamus ma ọ bụ homonụ nke na-ewepụta thyotropin, edebeghị ya ruo taa.

Azụ hypothyroidism n'ime ụmụ anụmanụ na-etolite n'ihi cretinism, ebe ọ bụ na homonụ nke gland na-emepụta dị mkpa maka ịmepụta eke nke akwara na akwara na akwara. Ọzọkwa, e depụtawo okwu banyere enweghị ma ọ bụ mmebi nke gland thyroid, erughi iodine ma ọ bụ mmebi homonụ.

Hypothyroidism nke abụọ dị na Congenital, dị ka a na-achị, na-apụta na ndị ọzụzụ atụrụ ndị German nwere hypothalamic hypoplasia - panhypopituitarism.

Ọzọkwa, a chọpụtara erughi erupụta na njikọ nke hypothalamus site na homonụ nke na-ewepụta thyrotropin na risenschnauzer. Ọrịa mbufụt thyroid (lymphocytic familial thyroiditis) na-aga n'ihu na Danish Great Danes, greyhounds na beagles.

Kedu usoro na akụkụ ahụ nke hypothyroidism na-emetụta ụmụ anụmanụ

N’ebe a na-anabata oriri, anụ ụlọ na-ekwupụta mgbaàmà na nkịta ma ọ bụ nwamba dịka:

okpomọkụ n'anya
imegusi,
oyi anagide
adịghị ike
ugboro ugboro ọrịa nke anụ ahụ,
dementia
hyperpigmentation
I nweta ibu
dandruff
siri ike molt
dull, uwe mkpuchi,
na-eto ngwa ngwa ntutu.

Udiri oria a na-enwekarighi bu amaghi aru, oria aru, oke isi, ito isi na nkochi.

Ọrịa niile na-amalite nwayọ nwayọ nwayọ.

Ebe ọ bụ na hypothyroidism na-aga n'ihu n'usoro, ọtụtụ ihe otu ahụ nwere ike imebi na anụmanụ n'otu oge.

Ya mere, enwere ike ịhụ ihe mgbaàmà doro anya site na:

anya
usoro ụjọ
sistemu ụjọ
anụ ahụ
usoro homonụ
eriri afọ
sisitemu obi
usoro endocrine
usoro ịmụ nwa na akwara ozi.

Ihe enwere ike ịchọta mgbe ị na-enyocha nkịta maka hypothyroidism

Na nkịta na nwamba, a na-ahụ alolecia (Symmetrical). Ọtụtụ mgbe na mbido, isi nkwọcha na-emetụta akụkụ, akụkụ nke esemokwu (afọ, akpa, olu), ntị na ọdụ. Na nmalite nke ọrịa ahụ, isi nkwọcha nwere ike ịbụ asymmetric na multifocal.

Afọ isi anaghị eso ya mgbe niile na itching, ma ọ bụrụ na enweghi ọrịa purulent nke abụọ ma ọ bụ ihe ndị ọzọ na-akpalite itching. N'okwu a, ajị anụ ahụ na-agbaji n'enweghị nnukwu mbọ.

N'oge nyocha ahụ, onye na-ahụ maka anụ ahụ na-achọpụta ihe mgbaàmà ndị dị ka ịmụzigharị ụkọ na obere mmebi anụ ahụ na akwa mmanụ ma ọ bụ seborrhea na-adịghị, nke nwere ike ịbụ multifocal, izugbe ma ọ bụ mpaghara. Ọzọkwa, anụ ahụ nke anụmanụ nwere ike ịma mma, oyi, dent, ntutu nwere agba dull, bebi, dull, akọrọ.

Na mgbakwunye, nkịta ma ọ bụ nwamba nwere ike ịnweta mgbaàmà nke myxedema dị mwute. A ka na-ahụ hyperkeratosis, hyperpigmentation na ijikọ anụ ahụ na mpaghara ọgụ. Ọzọkwa, ọgwụgwọ anụ ahụ nwere ike ịchọpụta pyoderma (ọ na - esighi ike, nke na - adịkarịghị omimi) yana mgbasa ozi otitis.

Mgbaàmà ndị a na-ahụkarị

Mgbaàmà ndị a na-ahụkarị bụ hypothermia na-erughị ala, ike ọgwụgwụ, oke ibu, na dementia.Site n'akụkụ nke sisitemu obi, bradycardia, nsogbu akụkụ na-adịghị ike na mkpali apical na-ahụkarị. Ma ihe omumu omumu bu:

testicular atrophy na mbelata nke libido n'ime eriri,
amụghị nwa
emeputa mmiri ara ehi n'oge a na-ata ahịhịa,
enweghi estrus (anestrus na-adi ogologo) na bitches.

Nlekota Ndidi

Mgbe ịmalite ọgwụgwọ, a na-achọpụta ọganihu na ahụike anụmanụ na ụbọchị 7-10. Ọnọdụ nke uwe na akpụkpọ ahụ dị mma mgbe ọnwa 1,5-2 gasịrị. Ọ bụrụ na mgbanwe agbanwebeghị, mgbe ahụ, ọgwụgwọ anụ ahụ kwesịrị ịtụle nchọpụta ahụ.

N'oge nleba anya, ya bụ n'izu asatọ nke ọgwụgwọ, dọkịta ahụ na-atụle ịta ọbara ọbara nke T4. Ogologo ọkwa ọbara T4 kachasị elu mgbe nchịkwa L-thyroxine na-enweta mgbe awa 4-8 gachara.

Ọ dị mkpa na onye gosipụtara tupu iwebata ego bụ ihe nkịtị. Ọ bụrụ na mgbe nchịkwa ọgwụ ahụ, ọkwa ahụ ka na-anabata, ma tupu nchịkwa ahụ, ịta ahụ dị ala, mgbe ahụ, ekwesịrị ịbawanye ugboro nke nchịkwa ọgwụ.

Y'oburu na eweda ihe ngosi gi ala, oputara na nke a na - egosi:

usoro ọgwụgwọ adịghị mma
onye nwe ya adịghị enye ọgwụ ya,
ịba n'ime eriri afọ,
iji ọgwụ dị ala (emebiela, echekwa nke ọma).

Ọkpụkpọ ọgwụ mgbochi na T3 na T4 na-egbochikarị ịgbakọ ogo hormone. N'ọnọdụ ndị a, ọgwụgwọ anụ ahụ na-eji njimara ụlọ ọgwụ iji chọpụta izu oke nke ọgwụgwọ yana ị doseụ ọgwụ.

Ihe mgbochi, nsogbu na prognosis

Maka mgbochi, ọ dị mkpa ka ị nyochaa ọkwa nke homonụ thyroid oge ụfọdụ iji gbochie nlọghachi ahụ ọrịa ahụ. Usoro ọgwụgwọ na-adị ogologo ndụ.

Mgbaze nwere ike ibilite site na oke nke L-thyroxine:

azumahia,
ọnọdụ enweghị nsogbu
afọ ọsịsa
polyuria
ifelata
polydipsia.

Maka ụmụ nwamba na nkịta nwere hypothyroidism nke mbụ yana iji usoro ọgwụgwọ nnọchi anya, prognosis dị mma. Yabụ, afọ ndụ anụmanụ anaghị ebelata.

N'ihe banyere hypothyroidism nke ụlọ akwụkwọ sekọndrị ma ọ bụ nke nke abụọ, a na-anabata prognosis, ebe ọ bụ na ụbụrụ gosipụtara usoro mmụta a. Site n'ụdị ọrịa ọrịa ọgbụgba n'oge ịmụ nwa, prognosis ahụ adịghịkwa njọ.

Ọgwụgwọ na-enweghị myxedema coma bụ outpatient. N’inye ọzụzụ kwesịrị ekwesị maka onye nwe anụmanụ, hypothyroidism na nkịta na nwamba nwere amụma dị mma. Na iji mee ka ndụ onye ọrịa dịkwuo ogologo, a na-eji mgbakasị hormonal eme ihe.

Dị Mkpa! N'oge ọgwụgwọ, o kwesịrị izere nri ndị nwere nnukwu abụba.

Banyere usoro ị drugụ ọgwụ ahụ, ọ nwere ike ịdị iche iche wee họrọ ya n'otu n'otu. Ya mere, omumu ihe banyere omumu nke homonu n’ime obara bu ihe nkwa n’ilegharia nke oma na oria. Nzaghachi anụ ahụ maka ọgwụgwọ bụ nke nwayọ, yabụ, maka nyocha zuru oke nke nsonaazụ ahụ, ọnwa atọ ka achọrọ.

N'ihi ọdịiche dị mkpa na usoro metabolic nke mmadụ na anụmanụ, usoro nke homonụ thyroid maka nkịta na nwamba dị iche iche.

Ejighị ịwa ahụ hypothyroidism.

Ọgwụ maka hypothyroidism

N'ịgwọ ọrịa ahụ, a na-eji svothyroxine sodium (L-thyroxine) eme ihe. Usoro ọgwụgwọ oge mbụ bụ 0.02-0.04 mg / kg / ụbọchị. Ọzọkwa, a na-agbakọ dose ahụ dabere na ịdị arọ nke anụmanụ ma ọ bụ nwamba dabere na oke nke anụ ahụ - 0,5 mg kwa 1 m2 kwa ụbọchị na usoro abụọ kewara.

Dịka iwu, iji nweta ọnọdụ kwụsiri ike, a na-a theụ ọgwụ ahụ ihe dị ka ọnwa 1.

Ingsdọ aka na ntị

Ọrịa shuga mellitus na nkịta ma ọ bụ nwamba, ma ọ bụ ọrịa obi - ọrịa nke ịchọrọ iji belata usoro onunu ogwu nke mbu n'ihi mbelata mmezi nke usoro metabolic. Na tupu ịmalite ọgwụgwọ na L-thyroxine, onye na-ahụ maka ọgwụgwọ anụ ahụ na-edepụta adrenocorticoids nye ndị ọrịa nwere hypoadrenocorticism (parallel).

Njikọ Ọgwụ

Ojiji n’otu oge iji ọgwụ eme ihe na-agbadata usoro nke ejikọtara whey protein (fentoin, salicylates, glucocorticoids) chọrọ ngbanwe n’usoro nke ọgwụ L-thyroxine ka ọ dị elu ma ọ bụ karịa na-eji ọgwụ a.

Ndị ọzọ gụnyere triiodothyronine. Agbanyeghị, etinyere ya ọgwụ adịkarịghị ala, ebe ọ bụ na ọgwụ ahụ na-enye aka na ọrịa hyperthyroidism nke ọrịa iatrogenic ma belata ọkara ndụ.

Ọkpụkpụ hypothyroidism n'ime nwamba

Ọ na-ebute dwarfism na-ezighi ezi ma nwee ike ịdapụta n'ihi agenesis ma ọ bụ dysgenesis nke gland thyroid ma ọ bụ n'ihi dishormonogenesis. A hụrụ mmebi nke thyroid peroxidase, nke na-eduga n'ịkpa ahụ ayodiin, na nwamba ntutu nwere oke mkpụmkpụ na nwamba nke ụdị Abisinini. Site na ụdị hypothyroidism, enwere ike ịtụ anya mmepe nke goiter. Na mgbakwunye, steeti hypothyroidism, n'ihi enweghị ike nke thyroid ịzaghachi homonụ na-akpali akpali (homonụ na-akpali akpali nke mkpụrụ ndụ, TSH), bụ ezinụlọ ezinụlọ nwamba. Ọrịa ndị a na - akpata hypothyroidism a na - amụkarị ka a na - eketa bụ àgwà akpaghachichara akpa ike.

A kọwawo ikpe ikpe gbasara hypothyroidism n'ihi ụkọ ayodiin na nwamba nke e ji nri eri anụ.

Hypothyroidism Iatrogenic na nwamba

Hypothyroidism Iatrogenic na-etolikarị n'ihi ọgwụgwọ nke hyperthyroidism na nwamba bụ ụdị hypothyroidism nkịtị. Iatrogenic hypothyroidism nwere ike ịmalite n'ihi nnwekọrịta thyroid nke abụọ, ọgwụgwọ iodine redioactive ma ọ bụ ọgwụ na-ebelata ọrụ thyroid.

Ihe mgbaàmà nke hypothyroidism feline

Ihe mgbaàmà nke hypothyroidism nwere ike ịfefe ma ọ bụ nwayọ dabere n'ụdị nsogbu nke metabolic, nke, dịka ọ dị na mmadụ, nwere ike ịbụ ele mmadụ anya n'ihu ma ọ bụ zuru ezu.

Ọtụtụ kittens metụtara emetụta tupu a na-enyo enyo na hypothyroidism. Imirikiti ụmụ anụmanụ na-ele anya ahụ ike ruo izu anọ na anọ, mana ka ọ gachara izu 4-8 ka uto ha na-adalata, enwere akara nke ịkpa oke: nnukwu sara mbara, obere aka yana obere ahụ. Ha nwere akara nke ịda mba, igbu mmụọ, ụdị nwamba ndị a adịghị arụ ọrụ ma e jiri ha tụnyere ndị ibe ha. Ezé na-etolite etolite ma dochie ezé ezé nwere ike gbue oge ruo ọnwa 18 ma ọ bụ karịa. Enwere akara nke mmechi na - egbu oge nke ọkpụkpụ ogologo. Uwe mkpuchi nke kittens na-anọchi anya ihe ndị uwe ojii na-eji obere ntutu dị n'èzí na-anọchi anya ya.

Na nwamba nwere hypothyroidism, ihe ịrịba ama nke ọrịa ahụ bụ mgbanwe na akpụkpọ (akpọnwụ akpọnwụ, ntutu isi na-enweghị atụ, ọdịdị na-enweghị isi) yana lethargy, ịda mba, bradycardia na hypothermia. Enwere ike iwepụ Wool ngwa ngwa, na ebe edoziworo ntutu, uto ya ugboro ugboro na-egbu oge. Alopecia nwere ike itolite, na nwamba ụfọdụ ntutu na-ada na mgba.

Nchoputa nke cat hypothyroidism

Na mbido, a na-eme nnyocha n’usoro ọkọlọtọ ọbara na ọgwụ ndị dị ndụ.

A na-enyocha ọkwa Hormone: mkpokọta T4 na TSH. A na-ejikwa Sambalị nwere mkpali TSH na ntinye nwere homonụ na-ewepụta thyrotropin.

Kpebisie ike n ’ịta isi T4 bụ nyocha nyocha mbụ kachasị mma maka hypothyroidism na nwamba nwere akara ịgba ama dị mkpa. Dị ka ọ dị, na nwamba nwere hypothyroidism, ntụpọ basal T4 dị n'okpuru ala nke oke kwesịrị, na mgbe ụfọdụ, enweghị ike ịchọpụta. Ntinye uche nke T4 na mpaghara nkịtị na-eme ka o kwe omume iwepu nchọpụta nke hypothyroidism, n'agbanyeghị nke a, ntinye uche dị ala anaghị akwado hypothyroidism, ebe ọrịa ndị ọzọ na ọgwụ ọjọọ nwere ike ibute ịba ụba na ntinye uche T4 na njirimara ọkwa hypothyroidism. Ọ bụrụ na akụkọ ihe mere eme na ihe ịrịba ama nke ụlọ ọgwụ kwekọrọ na ọrịa ahụ, obere nke T4, nke ahụ ga-akawanye njọ nke hypothyroidism na pusi. Ọ bụrụ na ogo nke ịchewe hypothyroidism na foto ụlọ ọgwụ ezughi oke, mana itinye uche nke T4 dị ala, ihe ndị ọzọ, dịka ọrịa na-esiteghị na gland thyroid, nwere ike yikarịrị.

A nwalere usoro iji chọpụta TSH nke ọma mgbe ejiri nwamba mee ihe. Agbanyeghị na uche nke usoro dị n'okpuru ezigbo adịghị mma, ntinye uche TSH dị elu na pusi nwere mbelata ngụkọta ọnụ bụ T4 bụ ihe akọwapụtara nke hypothyroidism. A kọwawo ịba ụba nke TSH na nwamba nwere hypothyroidism nke ịmụ nwa, hypothyroidism sitere na mkpụrụ obi, nke etolite na okenye, yana hypothyroidism toat.

Nnwale na-akpali akpali na TSH yiri nke a na nkịta na nwamba, ma ewezuga ntakịrị ọgwụ ọgwụ thyrotropin. Nsonaazụ nke ọmụmụ nke nnwale na-akpali akpali na TSH enyewo ihe mere iji kwenye na nnwale a dabara adaba maka nchọpụta hypothyroidism na nwamba, agbanyeghị, nnwale a anaghị adịkarị na omume ụlọ ọgwụ n'ihi ọnụ ahịa dị elu nke TSH mmadụ.

A na-atụ aro nnwale homonụ nke na-eme ka mmiri dị n’ịchọpụta maka hypothyroidism na nwamba, agbanyeghị na-ejikarị ya maka ebumnuche a mana enyochabeghị ya dịka usoro iji chọpụta hypothyroidism na nwamba. Ma ọ bụrụ na nsonaazụ nke nnwale ahụ na mkpali nke TSH bụ ihe dị mma, mana nsonaazụ nke nnwale ahụ nwere homonụ nke na-ewepụta thyrotropin abụghị nke ahụ, nke a na-egosi nsị nke nkụda mmụọ.

Nchọpụta nke hypothyroidism na nwamba kwesịrị ka dabere na njikọta nke akụkọ ahụike, akara nke ụlọ ọgwụ, nsonaazụ nyocha nke ụlọ ọgwụ, mkpo ọka thyroxine dị ala na ịbawanye n'ọtụtụ TSH. Iji mata mgbanwe ndị na-egosi hypothyroidism ma chọpụta ọnụnọ nke ọrịa ndị ọzọ, ọ dị mkpa ime nnwale ụlọ nyocha nke mbụ: nyocha ọbara ọbara, nyocha ọbara nke biochemical, na urinalysis. Nke a dị mkpa n'ihi na ọrịa ndị ọzọ nwere ike imetụta mkpokọta homonụ thyroid, yana ojiji nke ọgwụ (dịka ọmụmaatụ, glucocorticoids).

Ọgwụ maka Hypothyroidism na Nwamba

Hypothyroidism na nwamba nwere ike ịdị nwa oge, nke pụtara na ka oge na-aga, ọ ga-apụ n'anya. Ihe atụ bụ nwamba na-etolite hypothyroidism n'ihi ọgwụgwọ iodine redioactive ma ọ bụ ịwa ahụ. Nke a na-ewe oge maka ahụ ha iji wulite ma bido meziwanye usoro ọgwụgwọ thyroid. Ebe ọ bụ na hypothyroidism feline nwere ike ịdị nwa oge, ọ nwere ike ọ gaghị achọ enyemaka na ọgwụgwọ. N'ọnọdụ ụfọdụ, hypothyroidism anaghị arụ ọrụ nke aka ya. N'ọnọdụ ndị a, pusi chọrọ ọgwụgwọ n'oge ndụ ya niile.

Maka ọgwụgwọ nke hypothyroidism, a na-eji ọgwụgwọ mkpụrụ ọgwụ eme ihe n'ụdị ụdị homonụ na-akpụ akpụ. Ọtụtụ mgbe, ọ na-ewe oge ịchọpụta ọgwụ ole ọ theụrụ ọgwụ ahụ, ebe ọ bụ na homonụ nke thyroid nwere ike ịgbanwee ma gbanwee ka oge na-aga. Onye na-ahụ maka anụ ahụ na-eme mkpebi na ịhazigharị ọgwụ ole ọ dị n'ọgwụgwụ ndụ nke nwamba, dabere n'ọnọdụ anụ ahụ nke pusi na mgbanwe na ọkwa nke homonụ thyroid mgbe ị na-edepụta ọgwụ.

Na nwamba nke na-anata ọgwụgwọ nnọchi anya na nkwadebe homonụ na-ahazi iji mezie ọrụ thyroid, mgbaàmà nke hypothyroidism na-apụ n'anya mgbe ọnwa ole na ole gachara ọgwụgwọ. Nwamba kwesịrị ka edepụtara ọgwụ mgbochi thyroid kwa ụbọchị kwesịrị ka dọkịta ha nyochaa ya mgbe niile ma nye onyinye ọbara na ọkwa nke homonụ ndị a. Ọ bụrụ na dibịa na-ahụ maka ọnụnọ na-achọpụta mgbanwe nke homonụ thyroid, mgbe ahụ ọ na-agbanwe usoro ị theụ ọgwụ ahụ.

Usoro ọgwụgwọ maka nwamba nwere hypothyroidism nwere ike ịdị mgbagwoju anya ma na-eyi egwu. Ọ bụrụ nwamba na-achọpụta ọrịa hypothyroidism, nke na-abụghị nwa oge ma chọọ nhọpụta ọgwụgwọ ọzọ na ịchịkwa ọkwa nke homonụ thyroid, mgbe ahụ ọ ga-adị mkpa ka onye nwe ya megharịa ọnọdụ ahụike nke pusi ahụ. N'ọtụtụ oge, a na-edenye ọgwụ kwa ụbọchị ruo ọgwụgwụ nke ndụ, na-eduzi ule ọbara mgbe niile, ma ihe ngosi bụ nke ọma ma chọpụta ọkwa nke homonụ thyroid. Enwere ike ịchọ mgbanwe nri iji jikwaa akara nke hypothyroidism. Nwamba nwere ọrịa thyroid na-ebelata chọrọ usoro nlezianya maka ọgwụgwọ nke hypothyroidism na-adịghị ala ala.

Otu akụkụ dị mkpa bụ idebe ndụmọdụ niile nke dibịa na-aga. Ọ dị mkpa ịbanye n'ụzọ ziri ezi ị drugsụ ọgwụ ọ bụla dọkịta gị depụtara. Emebela onwe gị mkpebi maka ịgbanwe etu ị theụ ọgwụ ahụ na ịgaghị na-ahụ dọkịta gị, n'ihi na ọgwụ na-ezighi ezi nwere ike gbanwee oke ọrụ nke akwara gland ahụ ma mee ka ọ nwee mmetụta na-adịghị mma.

Ọ dịkwa mkpa iburu n’obi na ndị nwe ụlọ ekwesịghị iwebata nri ma ọ bụ ọgwụ ọhụụ n’ebughị ụzọ kpọtụrụ onye na-ahụ maka ọrịa anụ.

Nsogbu homonụ ma ọ bụ hypothyroidism na nwamba: siri ike ịchọpụta, ọ fọrọ nke nta ka ọ ghara ịgwọ

Otu n'ime akụkụ dị mkpa nke zoro ezo n'ime anụ ụlọ bụ gland thyroid. Homonụ thyroid mepụtara (triiodothyronine na thyroxine) na-ekerekwa n'ihe fọrọ nke nta ka ọ bụrụ usoro metabolic niile. Mbelata nke homonụ a na-emepụta site na ígwè na-eduga hypothyroidism, nke bụ oria a na-adịghị ahụkebe n'etiti ndị nnọchi anya ezinụlọ cat.

Pathology na-ebute nsogbu nke sistemu n'ihi mbelata nke usoro metabolic na ahụ. Ihe kpatara oria a bu ihe nlere anya nke ulo ogwu, ihe isi ike nchoputa, na ogwugwo ya doziri ya.

Gụọ akụkọ a

N'ime ọgwụ ọgwụgwọ anụ ahụ, a ghọtaghị ihe ndị na-akpata mmepụta homonụ nke thyroid na nwamba nke ọma. Ekwenyere na ihe so akpata ọrịa a:

1 - gland thyroid dị mma, 2 na nke 3 - ọrịa parathyroid bụ ihe dị mma, 4 - mbufụt nke thyroid gland

Eketa. Ihe mkpụrụ ndụ ihe nketa na-emetụta n'ụzọ dị mma na ntụpọ dị na njikọta nke thyroxine na triiodothyronine.

Certainnweta ọgwụ ụfọdụ. Ọgwụ corticosteroid dị ogologo nke ọgwụ mgbochi mkpali na-edugakarị na mmepe nke ụkọ thyroid na nwamba.

Enwere ihe akaebe nke mmetụta ọjọọ na mmepụta nke homonụ thyroid nke ọgwụ dịka Phenobarbital. A na - eji ọgwụ barbituric acid mee ihe n'ọtụtụ ebe iji nweta ọgwụ mgbochi n'ime anụmanụ.

Rodahosis na-eji iodine isotopes. Ofgwọ ọrịa kansa na-eduga n'eziokwu ahụ bụ na ayodiin ayodiin na-egbochi ọrụ homonụ nke gland thyroid.
Mwepu akụkụ ahụ dịka otu ihe si dị. A na-emekarị thyroidectomy nwamba banyere hyperthyroidism, ọnụnọ nke etuto ahụ na-emebi emebi na akwara.
Ọtụtụ mgbe, ihe kpatara ọrịa ahụ bụ enweghị ayodiin na nri. Enweghị ntụpọ nke Chọpụta na-eduga n'ọgba aghara na biosynthesis nke triiodothyronine na thyroxine site na gland.
Usoro mmerụ ahụ na-etolite na thyroid gland bụ ihe na-akpata ọrịa.
Ọrịa cancer ara na-akpata Oncological na-ebutekarị mmepe nke ụkọ thyroid na nwamba ụlọ.

Ihe omuma nke zuru oke banyere ihe kpatara ọrịa oria endocrine n'ime anumanu na-agbagha ọ bụghị naanị mmepe nke mgbochi, kamakwa nchọpụta nke pathology.

Ọkpụkpụ nke homonụ thyroid na-emetụta akụkụ ahụ niile yana sistem nke ahụ. Usoro ahụ ji alụso ọrịa ọgụ, nri na usoro ụjọ na-emetụtakarị. Ọrịa nke anụahụ.

Ọtụtụ mgbe, hypothyroidism na nwamba ụlọ na-egosipụta mgbaàmà ndị a:

Ike ọgwụgwụ, enweghị mmasị, nkụda mmụọ, na-egbochi ọnọdụ nke anụmanụ. Nwamba anaghị eso na egwuregwu dị egwu, anaghị eze arụ ọrụ. Ends na-etinyekwu oge ọkara ụra na nrọ.
Coat dị n'ọnọdụ anaghị eju afọ. Uwe a dull, na-emebi emebi, mmanu mmanu na emetụ aka. A na-achọpụta akwa prolapse na-esoghị maka ịtụgharị ihe.
A na-eji ntutu ọhụụ agbaze na alopecia a na-enwe ebe ntutu nwere ntutu. Agbanyeghị, ọnọdụ ya na-ahapụ ọtụtụ ihe ịchọrọ.
Ọbara hypothermia. Mbelata nke ahụ ọkụ bụ n'ihi nwayọ na usoro metabolic dị n’ahụ. Onye nwere ya nwere ike inyo hypothermia na anụmanụ site na omume ya. Pusi na-achọ ịhọrọ naanị ebe dị ọkụ, hapụ ịhapụ ha.
Mmachi nke usoro metabolic dị n’ahụ nke pusi na-arịa ọrịa na-eduga na mbelata ọtụtụ ụdọ obi. Bradycardia bụ otu n'ime ihe ndị a na-ahụkarị na ọrịa thyroid na-akụ afọ n’ala.
Imirikiti ụmụ anụmanụ buru oke ibu.
Ntachi afọ.

N'ime usoro ọgwụgwọ anụ ahụ, ọ bụ ọdịnala ịmata ọdịiche dị n'etiti ụdị isi na nke abụọ nke ọrịa metụtara enweghị homonụ thyroid. Ihe ruru 90 - 95% nke ikpe gbasara nsogbu ịba ọcha n'anya na nwamba ụlọ na-esonye na usoro mbụ.

Ọrịa na - ebilite megide nzụlite nke phenomena dịka thyroid hypoplasia na prenatal development, mmebi nke akụkụ ahụ, thyroidectomy, ọgwụgwọ ogologo oge na iodine radioisotopes, yana iji ọgwụ antithyroid.

Hypothyroidism nke abụọ na nwamba ụlọ na-akwụghị 5%. Ejiri oria a na imebi ihe nzuzo nke homonụ na-akpali akpali site na ọnya pituitary. Ọrịa dị otú ahụ na-etolite, na-abụkarị n'ihi ọrịa ma ọ bụ mmerụ nke ọnya ụbụrụ nke ụbụrụ.

A na-ahụkarị akara ngosipụta nke ọrịa na-akpata ọgba aghara nke endocrine na anụ ụlọ dị ka akara nke ọtụtụ ọrịa. Ọ bụrụ na a na-enyo oria, na mgbakwunye na nyocha ahụike zuru ezu, a ga-eduzi ọtụtụ ụzọ nchọpụta ọrịa na nyocha ụlọ nyocha n'ụlọ ọgwụ anụmanụ.

Nke mbu, enyere umu anumanu ihe omumu nke obi. On a electrocardiogram na hypothyroidism, bradycardia akpọ, gbawara nke ụda obi, ịgbatị oge nke PQ na T ife.

A na-amata nnwale ọbara ọbara gbasara oligochromia, hypochromia, neutropenia na lymphocytosis. Mgbe mgbe, anụmanụ nwere oke ana - - enyocha. Diagnozọ nyocha kachasị maka ọrịa endocrine bụ nyocha ọbara maka ịta nke homonụ thyroid.

N'ihe banyere adịghị ike hypothyroid, mbelata ọkwa nke homonụ nke triiodothyronine na thyroxine, a na-achọpụta mmụba nke homonụ na-akpali akpali. N'ọnọdụ ụfọdụ, ha na-enyocha nyocha nke ndepụta maka ọdịnaya nke ayodiin dị na ya.

Mgbanwe na ọkwa homonụ na hypothyroidism

Ọrịa dị iche iche nwere ebe dị mkpa, ebe ọ bụ na ihe mgbaàmà nke hypothyroidism yiri nke ngosipụta nfụkasị, dermatitis, ọrịa nke usoro ahụ ji alụso ọrịa ọgụ, ụkọ vitamin, na ọrịa shuga mellitus.

Usoro ọgwụgwọ endocrine pathology na omume ọgwụgwọ anụ ahụ bụ, dịka iwu, dochie anya okike. Iji mezuo nke a, a na-eji homonụ thyroid na-akpụ akpụ, dịka ọmụmaatụ, Levothyroxine, L-thyroxine, Bagothyrox.

A na-enye ọgwụ ọgwụ mmadụ Levothyroxine, nke a na-ejikarị na endocrinology veterinary endocrinology, na-achịkwa na ọkara nke 10-15 μg / kg nke ibu anụmanụ. N'ihi eziokwu ahụ bụ na ọkara ndụ nke homonụ a bụ ihe dị ka awa iri na ise, ọ na - eji ọgwụ hormonal eme ihe ugboro abụọ n'ụbọchị. Ọ bụ ojiji nke okpukpu abụọ na-enye gị ohere ịmegharia uche nke thyroxine n'ọbara ọbara nke anụmanụ na-arịa ọrịa.

Usoro ọgwụgwọ mmegharị homonụ maka hypothyroidism

Ihe isi ike nke iji usoro ogwu eji agwo oria maka oria endocrine na anumanu di n’ime mkpa ichota ogwu ogwu nke homonụ na-agbanwe agbanwe. Ihe dị ka izu atọ ruo izu anọ nke iji ọgwụ ọgwụ ọria bidoro usoro ọgwụgwọ ga - amalite ịgwọ plasma thyroxine na anụmanụ. Dabere na ihe ngosi nke homonụ ahụ, a na-edozi usoro nke homonụ sịntetik.

Ihe kachasị mkpa na nhọpụta ọgwụ iji dochie anya ọgwụ bụ nchọpụta nchọpụta ziri ezi. Nlekọta nke Levothyroxine maka ụmụ anụmanụ nwere ahụike nwere ike ibute mbelata mmepụta nke homonụ na-akpali akpali site na pituitary gland na mmepe nke hyperthyroidism. N'akụkụ a, ọtụtụ ndị ọkachamara na ọgwụgwọ ọrịa anụmanụ na-atụ aro ịmalite ọgwụgwọ nke anụmanụ site na iji ọgwụ herbal na homeopathic.

Ọ bụ naanị dọkịta ruru eru nwere ike ịkọwa usoro ọgwụgwọ ọgwụgwọ ruru eru nke nwere ike dabere na nyocha ụlọ nyocha. Onye nwe ya kwesịrị ịmara na ọgwụ ndochi bụ ogologo ndụ.

Thezọ ọrịa na-adịghị ala ala, ihe isi ike ịchọpụta na ịkọwa ọgwụ ọgwụ homonụ na-eduga n'eziokwu ahụ bụ na ndị na-ahụ maka anụ ahụ na-enye prognosis dị akọ. Site na iji homonụ ọ bụla ahọpụtara homonụ nke anụmanụ, ọnọdụ izugbe na-akawanye mma, mana enweghị mgbake ọ bụla.

Enweghị hypothyroid bụ otu n'ime ọrịa ọrịa endocrine dị mgbagwoju anya na anụ ụlọ. Mmetụta ọrịa nke akara, njikọta nke mgbaàmà ya na ọrịa ndị ọzọ na-eme ka o sie ike ịchọpụta ọrịa ahụ. Nchọpụta ọrịa chọrọ dibia bekee ka ọ nwee ọkaibe ma nwekwaa ahụmihe. Usoro ọgwụgwọ a bụ nke ejiri dochie anya ya ma nye ya anụmanụ maka ndụ ya.

Banyere hypothyroidism na nwamba, lee vidiyo a:

Ihe dị ka 15% nwamba na-enwekarị nsogbu ndị siri ike na usoro ụjọ, na. Ọrịa systemic nke akụkụ ahụ dị n'ime: ọrịa shuga, hypothyroidism.

Kedu ihe ọghọm nke toxoplasmosis na nwamba maka anụmanụ na ụmụ mmadụ. . Hypothyroidism, ọrịa shuga mellitus, etuto ahụ ọjọọ.

Nsogbu banyere oke ibu na nwamba na-eyiwanye egwu maka ndị ọrụ anụ ahụ. Ọgwụgwọ maka nwamba kwesịrị ịmalite ozugbo.

Nabata zootvet.ru! N'ebe a, ị nwere ike ịkpọtụrụ onye na-ahụ maka anụ ụlọ, yana ị nweta ozi gbasara ọrịa anụ ọ na-arịa. Jụọ ajụjụ gị ma anyị ga-enwe obi ụtọ ịza ha n'ime awa 24!

Enyere ozi dị na saịtị a maka ebumnuche ọhụụ. Ejila onwe gi ogwu. Na akara izizi nke ọrịa anụ ụlọ gị, kpọtụrụ vetiran soja gị ozugbo.

N’oge na-adịghị anya, anyị ga-ebipụta ozi.

Ọrịa na ụzọ isi gwọọ hyperthyroidism na nkịta na nwamba

Hyperthyroidism na anụ ụlọ bụ ọrịa thyroid na-agbakwunye mmepụta ụba nke homonụ ya. Na ọnọdụ a na-arịa ọrịa, a na-ahụta nnukwu mkpokọta nke thyroxine na triiodothyronine. Nmebi a na-eduga na mmụba dị ukwuu na usoro nke metabolic, nke na-emetụta ọrụ nke akụkụ ahụ na sistem niile na anụ ahụ.

Hyperthyroidism na nkịta dị ụkọ. Nnyocha e mere na-egosi na ọ na-abụkarị naanị otu onye na-arịa ọrịa kwa ihe dị ka otu narị na narị ise na iri ise na ise. Nnukwu nkịta na ndị na-ajụ ajụ na-agbakarị hyperthyroidism. Obere umu nwere obere nsogbu nke oria a. Achọpụtaghị na ihe metụtara hyperthyroidism na nkịta.

Hyperthyroidism na nwamba na-emekwa. Ọ na - emetụta ụmụ anụmanụ site na afọ 8. Kachasịsị anya bụ ihe a chọpụtara n’otu n’otu n’afọ 12-13. Ọrịa ahụ na-emetụtakwa ma nwoke ma nwanyị. Ọzọkwa, ozuzu nwamba anaghị emetụta ụzọ ya.

Ọrịa hyperthyroidism na-etolite ma ọ bụrụ na anụmanụ ahụ gbubiri nke ukwuu n'oge mmegharị ahụ. Nke a butere ọrịa na-efe efe n’ime ahụ nne, nke kpasuru oke oke homonụ thyroid n’ nwa amụrụ ọhụrụ ma ọ bụ nwa pusi.

Mgbe amuchara anumanu ahu, a na - ahụbe uto kpụ ọkụ n’ọnụ anụ ahụ niile, nke chọrọ ọtụtụ nri na ihe ndị na - arụ ọrụ nke ọma. Dika oke ike gwuru nne, ka karia imu nwa n’aru nwa. Ya mere, ka ọ na-erule ọnwa 4, ha nwere ụkọ nke homonụ thyroid, nke na-eduga hypothyroidism. Nke a bụ ihe megidere hyperthyroidism.

Ọzọkwa, ọnụọgụ ọrịa nke afọ site na usoro ọnụnọ nke anụ ahụ n'ime anụ ahụ. N'ihi ya, usoro ahụ ji alụso ọrịa ọgụ na-amalite imepụta ọgwụ mgbochi ọgwụ nke na-emebi gland thyroid ma na-emetụta ọrụ na ọnọdụ nke akụkụ ahụ na sistem niile.

Ọbara hyperthyroidism nwere ike pụta n'ihi ihe ndị a:

iwebata oke oke homonụ thyroid n’arụ nkịta ma ọ bụ nwamba,
Ọ nwere akpụ nke akpụ akwara nke thyroid gland, nke bụ ihe ana - egbochi homonụ. A na-akpọ ya thyroid carcinoma. Ọrịa dị otú ahụ dị ụkọ.
ọnụnọ nke ọrịa ọgbụgba,
tụụrụ ime
mmepe nke usoro mkpali na-adịghị ala ala nke na-eji nwayọ bibie anụ ahụ nke gland thyroid. N'ihi ya, mkpụrụ ndụ ndị ọzọ na-emepụta oke homonụ nke ukwuu.
iodine ngafe ke ahu nke anumanu.

Isi ihe na-eduga na mmepe nke hyperthyroidism na ụmụ anụmanụ bụ benignplasia ma ọ bụ thyroid adenoma. Nnukwu mmụba na akụkụ a na - esonyere ya, nke nwere ụyọkọ mkpụrụ vaịn. Na 70% nke ikpe, emetụta lobes abụọ nke gland thyroid.

Ihe ịrịba ama nke ihe banyere hyperthyroidism na ụmụ anụmanụ bụ:

Enwere mgbanwe dị ukwuu na omume. Anụmanụ na-emekwa ka ahụ ghara izu ike, oge ọ excụ ọzọ na -agagharị. Nwamba ma ọ bụ nkịta nwere ike igosipụta ihe ike na mbụ na-akwadoghị ya,
oke belata nke ukwu, nke nri na-a excessiveụbiga ya ókè sokwa,
obi obi na-abawanye
a na-achọpụta nsogbu nri.

ahu ya na-adi elu
A na-ahụ mkpọtụ nke nsọtụ ya,
ụmụ anụmanụ na-a aụ nnukwu mmiri mmiri,
pusi ma ọ bụ nkịta tụfuru ntutu isi ya, na-agbachasị agbachasị,
anya hụrụ (na-emechi nkuchi anya). Nke a bụ ihe ịrịba ama banyere mmepe nke ọrịa basedova,
enwere mmụba na gland thyroid, nke a na-enwe n'oge palpation nke olu,
ugboro ugboro
mgbe ụfọdụ enwere mmụba n'ọbara, nke nwere ike ibute ọhụụ na anụmanụ.

A na-egosipụta hyperthyroidism na nwamba na nkịta n'otu ụzọ ahụ ọdịda ọdịda, ọrịa imeju, ma ọ bụ neoplasia. A ga-ewepụrịrị ọnọdụ ndị a na-arịa ọrịa n'oge nyocha nke ọnọdụ anụmanụ. Nnyocha nke nwamba ma ọ bụ nkịta kwesịrị ịgụnye:

nyocha nke ihe niile gbasara ọbara,
mkpebi siri ike nke ọkwa homonụ thyroid (mkpokọta T4),
urinalysis.

N'ụfọdụ, x-ray obi, ECG, coprogram ka egosipụtara.

Mgbe ị na-enweta nsonaazụ site na nyocha ọbara dum, mgbanwe maka ọnụ ọgụgụ mkpụrụ ndụ ọbara ọbara, hematocrit anaghị eme. N'ime otu ụzọ n'ụzọ ise nke ụmụ anụmanụ macrocytosis hụrụ. Nnukwu mkpa nke homonụ thyroid na-enye aka na ntọhapụ nke erythropoietin dị ukwuu, nke, n'aka nke ya, na-abawanye mkpụrụ ndụ ọbara uhie nnukwu. Cannwekwara ike ịchọpụta ọnọdụ akọwapụtara dị ka leukogram nchegbu.

Na-enyocha nnwale ọbara banyere mmiri ọgwụ nje, nnukwu ọrụ nke enzymes imeju, alkaline phosphatase, dị egwu. Agbanyeghị, a kọwara mgbanwe ndị a dị ka ndị na-adịghị mkpa. Ọ bụrụ na ntụpụ uche na usoro dị mkpa, ọ dị mkpa iburu n'uche ọrịa ndị a na-ekekọta ọnụ. Na nyocha nke electrolytes n'ọtụtụ ikpe, enweghị mgbanwe na-adịghị mma ọ bụla hụrụ. Ọzọkwa hyperthyroidism na-esoro mmụba nke ịta urea, creatinine.

N'ọtụtụ oge, iji mee nyocha ziri ezi, o zuru ezu iji chọpụta ọkwa nke thyroxine dị n'ọbara anụmanụ. E gosipụtara ọnụnọ nke ọrịa site na mmụba na mkpokọta nke hormone a. Y’oburu na emechara nyocha, a na - achoputa ihe ndi n’egosiputa ihe di elu, odi nkpa imeghari ihe omumu a mgbe izu abua abua abua rue. Nsonaazụ a nwere ike igosipụta ọnụnọ nke ọnya na-eke nkụ.

Ebumnuche nke hyperthyroidism n'ime ụmụ anụmanụ kwesịrị iji belata ọkwa nke homonụ thyroid.

E nwere ọtụtụ ụzọ isi mee nke a:

radiotherapy na iodine redioaktivu. Ọ bụ ọgwụgwọ kachasị mma. Ihe isi ike na usoro a jikọtara ya na nkwado teknụzụ ụkọ maka ụlọ ọgwụ anụmanụ,

ọgwụgwọ ịwa ahụ. Ọ na-eduga na nsonaazụ dị mma, ma na-enye gị ohere ikpochapụ mgbaàmà na-akpaghasị kpamkpam. N'oge usoro ịwa ahụ, a chọrọ ụfọdụ ahụmịhe nke dọkịta na-awa ahụ, nke na-anaghị ekwe omume ịnweta mgbe niile. N'ihi mwepụ nke gland thyroid na-ekwesịghị ekwesị, a na-ahụ ihu abụọ na mmebi mberede nke glands parathyroid. Ndepụta nke nsogbu ịmụ nwa na-esochikwa mmepe nke ọrịa Horner, nkwonkwo nkwonkwo,
ogwu ogwu. Ọ bụ ọgwụgwọ a na-ahụkarị nke na-ewe ogologo oge. N'ọtụtụ oge, a na-eji ọgwụ ndị sitere na thiourea, nke na-egbochi mmepụta nke homonụ thyroid. Veterinarians na-eji ọgwụ ndị a - Carbimazole, Metimazole, Tiamazole na ndị ọzọ. A na-ejikarị ọgwụ mgbochi Beta eme ihe iji kpochapụ ihe mgbaàmà obi.

Na usoro ọgwụgwọ hyperthyroidism na ụmụ anụmanụ, prognosis bụ ihe dị mma (enweghị ọrịa dị oke njọ). Ọ dịkwa ezigbo mkpa na onye nwe ya na-agbaso ndụmọdụ nke ọgwụgwọ ọrịa anụmanụ. Ma ọ bụghị ya, ịdị irè nke ọgwụgwọ ga-abụ ihe efu. Prognosis nke hyperthyroidism dara ogbenye na mmepe nke usoro arụmọrụ na nkịta ma ọ bụ nwamba. Ọzọkwa, mgbake na mmezi ọnọdụ nke anụmanụ anaghị adị na ọnọdụ izugbe anụ ahụ.

Murray R., Grenner D., Human biochemistry // Biochemistry nke nkwukọrịta intracellular mmadụ na nkwukọrịta intercellular. - 1993. - p. 181-183, 219-224, 270.
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Naumenko E.V., Popova. P.K., Serotonin na melatonin na usoro usoro endocrine. - 1975. - p. 4-5, 8-9, 32, 34, 36-37, 44, 46.
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Ntụziaka maka mmanụ a amụ ambulance. nyere aka. Nke V.A. degharịrị ya. Mikhailovich, A.G. Miroshnichenko. Agba nke 3. St. Petersburg, 2005.
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Obstetrician-gynecologist, nwa akwukwo nke sayensị ọgwụ, DonNMU M. Gorky. Onye ode akwukwo banyere otutu akwukwo na saịtị isii

Hypothyroidism na ụmụ anụmanụ (hypothyreosis) - ọrịa nke na - egbochi ọrụ thyroid na mbelata ogo nke homonụ thyroid na ọbara.

Ọrịa hypothyroidism nke mbụ n'ihi ụkọ ayodiin n'ime ala, nri na mmiri.

N'okwu ndị a, a na-akpọ ọrịa ahụ goemat.

Ọrịa ahụ na-apụta na mmerụ ọrịa na -akpata ọnya ụbụrụ, ọnụnọ nke thyreostatics na nri ụfọdụ (rapeseed, kabeeji, tonip, soy), ọrịa thyroid na-adịghị ala ala, atrophy na mmerụ ahụ maka mmepe nke thyroid gland.

Ọgwụ hypothyroidism nke abụọ ọ bụ akpụ nke gwọchara gland na hypothalamus.

N'okpuru mmetụta nke ihe etiological, njikọta nke thyroxine (T4) na triiodothyronine (T3) na-egbochi n'ime ahụ, nke na-eduga n'ịbawanye uru nke ọkwa nke thyroid na-akpali homonụ (TSH).

Mgbanwe akwara na akwara na-egosi mmeju, ịmụba, mbufụt, granulomas na thyroid gland, mgbanwe mgbanwe na akụkụ ahụ ndị ọzọ.

Pathognomonic bụ mmụba dị ukwuu na gland thyroid (goiter).
Akpọnwụ akpọọla nkụ, na -ekwulata ụcha, na-ekpughe ọgba aghara na uto nke ntutu isi (oge na-egbu oge, uto ogologo, isi ike, ntutu na-agbacha agbacha n'oge)
Otu njiri mara nke ọrịa ahụ bụ imebi ọrụ nke akwara obi (bradycardia, ntị chiri, nkewapụ ụda nke obi, belata ọkụ ezé niile na electrocardiogram, ịgbatị oge nke PQ na etiti TQ).
N'ime ụmụ anụmanụ na-arịa ọrịa, mara adịghị mma ahụ, hypothermia, ịda mba, na ịrị elu nke ahụ.
N'ime ọbara, a chọpụtara oligochromia, hypochromia, neutropenia, lymphocytosis, mbelata ọkwa nke T3, T4 na mmụba nke ọdịnaya TSH.

Ọrịa ahụ adịghị ala ala amụma - kpachara anya.

A na-eme nchọpụta nyocha ahụ na-eburu n'uche ọdịnaya iodine dị na nri na mmiri, nyocha ahụike na ahụike yana nyocha ọbara nyocha.

Ọrịa dị iche na mellitus ọrịa shuga, hyperthyroidism, oke ibu, nke ọkwa nke T3, T4, TSH kwekọrọ na ụkpụrụ dị mma.

Hypothyroidism na nkịta bụ ọnọdụ ọrịa nke anụ ahụ na - etolite n'ihi ụkọ homonụ thyroid dị ogologo. Na nkịta, a na-edekọ ya ọtụtụ oge.

Ọkpụkpụ thyroid na-emepụta homonụ thyroid: triiodothyronine (T3) na tetraiodothyronine ma ọ bụ thyroxine (T4). A na-achịkwa ọkwa nke nzuzo ha na hypothalamus. A na-etolite homonụ tyroliberin ebe a. Ọ na - arụ ọrụ na akụkụ ọzọ nke ụbụrụ - glandia gland, nke na - ebute nguzobe nke homonụ na - akpali akpali (TSH). Ọ bụ TSH bụ nke a na-abanye n'ime ọbara na-emetụta mkpụrụ ndụ thyroid na-emepụta ma na-ezobe homonụ na-akpali akpali. Activedị arụmọrụ nke T4 na T3 na-eme ka ịhapụ thyroliberin na TSH kwụsịlata.

Ya mere, a na - ebugharị usoro mgbochi nke homonụ n’arụ ahụ, n’ihi nke a na-edozi nguzozi nke ime.

Hypothyroidism na nkịta nwere ike ịbụ nsonaazụ nke ọrịa ọmụmụ ma ọ bụ ọrịa enwetara.

E nwere ihe akaebe nke na-egosi ọdịnala mkpụrụ ndụ ga-adị hypothyroidism. Ọ bụrụ na nwanyị emepụtaghị homonụ thyroid n'oge ime, nwa ebu n’afọ nwere ike ibute nsogbu endocrine.

Dịka ọmụmaatụ, cretinism. Ọrịa a na-ebute ọrịa dị iche iche nke sistemụ akwara na oge na-egbu oge na mmepe anụ ahụ. Enwere nkọwa nke oke ngosipụta nke cretinism na nkịta. Anụmanụ ndị a anaghị agbazinye onwe ha na mmekọrịta mmadụ na ibe ya, ha anaghị anabata mmetụta ma ọ bụ oke iwe nke ụmụ mmadụ na anụmanụ, enweghị ike ịchọta nri ha.

Ọkpụkpụ hypothyroidism nwere ike ibute dwarfism. N'okwu a, nkịta nwere obere gbara oke ma ọ bụrụ na e jiri ya tụnyere anụmanụ ndị ọzọ nke otu nwoke, afọ na ụdị.

Ọ bụrụ na etisasị anụrị thyroid n’oge ndụ nkịta, nke a bụ ihe izizi enweta hypothyroidism.

Enwere ike ime ya site na:

Ọbara ọgbụgba akwara na - egbu egbu n'ihi mkpụrụ ndụ ihe nketa na usoro ahụ ji alụso ọrịa ọgụ. Mkpụrụ ndụ dị iche iche na - achọpụta mkpụrụ ndụ thyroid dị ka ihe si mba ọzọ wee buso ya agha. N’ihi nke a, izoputa hormone na-ebelata, ọkwa TSH ebili, hypothyroidism na-etolite. A na-akpọ ọnọdụ a autoimmune thyroiditis ma ọ bụ Hashimoto's thyroiditis.
Mgbanwe na akwara thyroid nke ọdịdị amaghi ma ọ bụ atiopicic atrophy nke gland thyroid.
Enweghị ayodiin na ndepụta, mmiri.
Ọkpụkpụ thyroid.
Ọrịa na-efe efe.

Kedu ihe ọghọm nke nnweta hypothyroidism nke nkịta nọ na nkịta? N'ihi mbelata nke njikọ homonụ na gland thyroid, a na-abawanye na mmepụta TSH na pituitary gland. Ihe isi ike bụ na njikọ nke TSH bụ oge ma ọ bụ “na - adọta” ọdịdị, yabụ ọtụtụ ụkpụrụ nwere ike ịdị ka ọ dị. Nke a bụ mmalite, a na-akpọkwa ya hypothyroidism ụgwọ. Edere ya na 7-18% nke anumanu.

Ogologo homonụ thyroid na-akọ na oge, ihe ndị ọzọ TSH na-emepụta n'ụba. Ogologo hypothyroidism nke dị ogologo oge na nkịta nwere ike ibute nsị nke TSH, nke ga-abanye ma ọ bụrụ na ọ nwere nnukwu nsogbu na usoro metabolic nke ahụ. Nke a bụ oge ọgwụgwụ ma ọ bụ hypothyroidism na-aga n'ihu.

Ọgwụ nwere ike imetụta ọkwa TSH site na ọgwụ ọgwụ, dịka sulfonamides, glucocorticoids, progesterone, na ndị ọzọ, na-enye nkọwa ụgha nke hypothyroidism nke mbụ.

Ọ bụrụ na nzuzo nke homonụ thyroid na-agbanwe n'ihi ọrịa nke akụkụ ahụ ndị ọzọ, mgbe ahụ a na-akpọ ọnọdụ a hypothyroidism nke abụọ enwetara. Nke mbu, nke a metụtara ezughi oke mmiri nke homonụ TSH n’ime gland pituitary.

Arụmọrụ nke akụrụngwa, usoro mkpali, etuto ahụ, ma ọ bụ mmerụ ahụ ọgbụgba. Na nke a, enweghị ọrịa na akwara thyroid gland n'onwe ya, mana ọ bụ ụkọ TSH na-akpata mgbanwe na mkpụrụ ndụ ya. Na omume, mgbanwe ndị a na-agbanweghi agbanwe na gland pituitary bụ obere.
Ojiji nke anticonvulsants na glucocorticoids, ma n'ụdị ọgwụ ọjọọ yana dịka akụkụ nke ngwaahịa eke.
Inwe nri n’adabereghị na ya.
Mwepụ nke glandị akwara.
Ọrịa ndị ọzọ: ọrịa obi na-adịghị ala ala ma ọ bụ akụrụ, sepsis, mmerụ ahụ ụbụrụ na ọtụtụ ihe. N'okwu a, isi ihe bụ na imebi ọnọdụ hormonal bụ nke abụọ, ekpebikwara na ọ bụghị site na ọrịa ahụ, kama site na ịdị njọ ya.

Isi ihe ọzọ dị mkpa. Enwere ọtụtụ ihe, dịka ọmụmaatụ, ịtụrụ ime ma ọ bụ ọrịa nke imeju, pancreas, ọrịa, nke nwere ike ịgbaghari ogo hormone nke thyroid na ọbara.

N'ihe siri ike nke hypothyroidism na nkịta, coma na-amalite. Nke a bụ ọnọdụ nke nsogbu ndị siri ike na-adị na ụbụrụ, sistem ụbụrụ na akụkụ ahụ ndị ọzọ. Ihe na - egbu egbu n’okwu a bụ ihe dịka 50%.

Nkịta nke ụdị anụ ndị a dị n'ihe ize ndụ maka hypothyroidism: dachshunds, minich schnauzer, poodles, cocker spaniels, igbe ọkpọ, ebe ndị Airedale, Dobermann pinchers, ndị na-eweghachi ọla edo, ndị na-eche ihu na Irish, Old English, Scottish, ndị ọzụzụ atụrụ German, Danish Great Danes. Bittes na-arịa ọrịa ihe dị ka okpukpu abụọ karịa nke ụmụ nwoke. Ọ dịkwa nkịta afọ 4 ruo 10 na-emetụta.

Hypothyroidism na nkịta na-amalite nke nta nke nta na enweghị akara doro anya ma ọ bụ nke akọwapụtara. N'okwu nke ọ bụla, njirimara nke anụmanụ nwere otu ihe dị ezigbo mkpa.

Nke mgbaàmà ndị a na-ahụkarị:

ike ọgwụgwụ, anụ ahụ belatara, mbelata ahu,
Ikike anụ ahụ na-abawanye maka ebum n’uche
na-enwe ndidi
mụbara inwe mmetụta oyi,
adighi ike na akwara ije,
ahumkpa ahu n’otu akụkụ nke ihe mucks: n'akuku ọnụ dara, ala ahụ anaghị emechi,
mebiri nke nzuzo nke lacrimal na salivary glands, ụtọ banyere ihe,
ọnya isi, mbufụt nke choroid nke eyeball ma ọ bụ uveitis,
nwayọ nwayọ na umeji,
nsogbu ọgbụgba,
ntutu dị njọ ma na-agbaji agbaze, na-amalite ịpụ n'akụkụ akụkụ ahụ nke akụkụ ahụ, na-amalite site na ọdụ, emesịa ahụ niile.
ọnyá afọ nke anụ ahụ na nke dị omimi nke anụ ahụ,
emezighituri na-agwọ ọnya, ngwa ngwa kpụrụ ọnya,
Ngosipụta nke “ahụhụ” nke ihe ọgbụgba ahụ n'ihi oke ọria nke anụ ahụ na ọnya nke dị n'okpuru ala, ọnya ahụ bụ ihe na-emetụ n'ahụ,
ahummadu na akpọnwụ akpọnwụ, afọ ntachi na nri imeghari,
amụghị nwa: na bitches, a na-agbagha usoro mmekọahụ. N'ime ụmụ nwoke, ụmụ ntakịrị atrophy na-enwe mmekọahụ na-ebelata, e dekọtara ọnwụ nke ụmụ nkịta.

Emere nchọpụta a dabere na ngosipụta nke ogo nke hormone T4, T3 na TSH n’ọbara ọbara nke nkịta. Enwere ule ndị ọzọ, dibia bekee na-atụ aro ha, dabere na njirimara nke usoro hypothyroidism.

Iji ghọta ọnọdụ nkịta ahụ dum, dọkịta ga-eduzi nyocha, nyocha ahụ ma dezie nyocha ọhụụ gbasara ọbara na mmamịrị, nyocha nke ọrịa concoitant site na iji ECG, ultrasound, radiography na ụzọ ndị ọzọ.

Isi ọrụ bụ ka eme ka akpụ akịrịka dị mma. Iji mee nke a, tinye ọgwụ ọgwụ na-eme ka ụkọ homonụ thyroid dị. Dịka iwu, ndị a bụ analogues nke homonụ. Site na usoro ọgwụgwọ zuru oke, mgbanwe mgbanwe mbụ dị mma na ọnọdụ nkịta ahụ ga-ahụ ọkwa n'otu izu na ọkara, yana ịdị mma nke ọgwụgwọ hormone n'ogologo mgbe ọnwa atọ gasịrị. N’ime ihe ọzọ, a ga-edenye ọgwụgwọ nke afọ ọsịsọ.

Ọ dị mkpa icheta: naanị vetiran soja na-ahọrọ ọgwụ na usoro ha n'otu n'otu. Cannweghị ike ịkwụsị ọrụ ọgwụgwọ ma ọ bụ ịgaghị agbaso ndụmọdụ ahụ, hypothyroidism nwere ike ịlaghachi.

Site na hypothyroidism congenital, dịka ọmụmaatụ, cretinism na ụmụ nkịta, prognosis adịghị mma, ebe ọ bụ na mgbanwe ndị a na-agbanwe agbanwe na irighiri akwara, usoro ọkpụkpụ na akwara na-apụta.

Site na hypothyroidism nke mbụ enweta, prognosis bụ ihe dị mma n'ihe gbasara usoro ọgwụgwọ oge na nchịkwa ndụ gị nke homonụ thyroid.

Site na hypothyroidism nke abụọ nwetara, prognosis na-adabere na ọnọdụ anụmanụ niile.

E zigara Rhodesian Ridgeback Adanna, 6 afọ na Nganga maka nhọpụta na endocrinologist Koroleva M.A. n'ihi nsogbu anụ ahụ. Mgbe a na-anabata oriri ahụ, ọ tụgharịrị na nkịta ahụ nwetara kilogram 10 dị arọ na ọkara otu afọ, na-arụ ọrụ nke ọma, na mgbanwe na-apụta na usoro mmekọahụ. Dabere na nsonaazụ nyocha nke izugbe, akụkọ ihe mere eme na eserese ụlọ nyocha, emere nchoputa nke mbu - hypothyroidism. Emere ọbara ọbara maka homonụ thyroid, nke gosipụtara ọnụnọ nke ọrịa ahụ. Dọkịta ekwuola ọgwụ iji dochie anya ọgwụ. Ọnwa atọ ka nke ahụ gasịrị, nkịta ahụ belatara nke ukwu, bịara nwekwuo ọ .ụ.

Ntụziaka maka endocrinology: monograph. , Ọgwụ - M., 2012 .-- 506 p.
Stroykova, A. S. Ọrịa shuga na-achịkwa. Ndụ zuru oke dị adị! / A.S. Stroykova. - M.: Vector, 2010 .-- 192 p.
Sidorov, P. I. Ọrịa shuga: akụkụ nke psychosomatic: monograph. / P.I. Sidorov. - M.: SpetsLit, 2017 .-- 652 p.

Ka m kọwaa onwe m. Aha m bụ Elena. Anọwo m na-arụ ọrụ dị ka ọkà mmụta endocrinologist ruo ihe karịrị afọ 10. Ekwenyere m na abụ m ọkachamara n'ọhịa m ugbu a, m chọrọ inyere ndị ọbịa niile na saịtị ahụ aka idozi ihe dị mgbagwoju anya ọ bụghị ọrụ. A na-achịkọta ihe niile dị na saịtị ahụ ma jiri nlezianya hazie iji kọọ ozi niile dị mkpa. Tupu itinye ihe akowara na weebụsaịtị, itinye aka na ndị ọkachamara na-adị mkpa mgbe niile.

Nnyocha ụlọ nyocha na ule

Nnwale Hormonal Radio Immune

Ọkwa ọbara nke T4 na T3 na ụkpụrụ dị ala na-egosi hypothyroidism, n'agbanyeghị, ọtụtụ ihe nwere ike belata ezigbo homonụ, gụnyere ọrịa na-abụghị thyroid (dịka ọmụmaatụ, glucocorticoids, anticonvulsants).

T4 na-akwụghị ụgwọ - na usoro ọgwụgwọ, ọbara ọbara nke T4 n'efu anaghị emetụta nnukwu ọrịa na ọrịa ndị ọzọ. Yabụ, ịnwale T4 na-akwụghị ụgwọ nwere ike ịbụ akara akara kachasị mma na nchọpụta nke hypothyroidism. Choicezọ ịhọrọ usoro nyocha na izi ezi nke ụlọ nyocha dị ezigbo mkpa, ebe ụfọdụ nnwale nwere nnwale nchọpụta dị ala.

Nnwale Ntinye nke Thyrotropin

N'oge gara aga, a na-ewere ya dị ka ule kachasị mkpa maka nchọpụta nke hypothyroidism, site na ịlele ntinye uche nke T4 tupu na mgbe nchịkwa bovine TSH.

E weere mbelata nke ịta T4 mgbe nchịkwa nke TSH dị ka hypothyroidism.

Availabilitydị nnwale a dịgasị iche na ọnụ ahịa dị elu maka ule a na-ebelata ngwa ya na omume zuru ụwa ọnụ.

Nwa nnwale nke na - ewepụtakwa homonụ na - ewepụta homonụ

Mmesho nke mmiri ọgwụ ọgbụgba nke TSH na nzaghachi na-akpali mkpali nke TSH-na-ahapụ ahapụ site na ịta nrịba nke T4.

Nnwale a ka dị ọnụ ala ma dị ọnụ ala karịa ụdị nnwale TSH.

Na nkịta, nkịta nwere hypothyroidism agaghị azaghachi ule a, agbanyeghị, ịkọwa nsonaazụ nnwale ahụ ka siri ike n'ihi mmekọrita nke obere mmụba na serum T4.

Akara TTG

Ogo TSH a tụkwasịrị obi maka ndị nkịta adịghị. Enwere ike ijikọ akụkụ ndị dị elu na hypothyroidism nke mbụ yana ọrịa na-abụghị thyroid.

Ihe omumu ndi ozo:

Ihe omumu ihe omumu nwere ike gosiputa mbelata nke akwukwo na myocardial.

ECG - obere voltaji nke ebili mmiri R ( Ntị! Ihe omuma a bu maka ntuziaka, adighi enye dika ogwu ike n’okwu nile. Nchịkwa ahụ na-ewepụ ibu ọrụ maka ọdịda na nsonaazụ na-adịghị mma na ojiji nke ọgwụ na ọgwụ ndị a. Cheta na anumanu nwere ike ime ka aru mmadu gwoo ya. Ọzọkwa, enwere ọgwụ mgbochi ị takingụ ọgwụ ọjọọ maka anụmanụ na ọnọdụ mgbochi ndị ọzọ. Site na itinye ozi enyere, kama ịnwe enyemaka nke ọkachamara n’ịzụ anụ, ị na-eme ihe ga-emerịrị gị. Anyị na-echetara gị na ị -ụ ọgwụ na nyocha onwe gị na-eweta naanị mmerụ ahụ.

Ọgwụ Ọgwụ maka Hypothyroidism

Ọgwụ maka ọgwụgwọ bụ sodium levothyroxine (aha ahia L-thyroxine). Dosages Starotov onunu ogwu nke 0.02-0.04 mg / n'arọ / ụbọchị ka akwadoro ịmalite ọgwụgwọ. Nkịta dị ukwuu ma ọ bụ pere mpe kwesịrị ịgbakọ karịa nke ọgwụ ahụ dabere na mpaghara ahụ (.0.5 mg / sq.m. / ụbọchị, kewara abụọ usoro). Ọtụtụ mgbe, izu izu 4 ka achọrọ iji nweta ọnọdụ kwụ chịm.

Ihe ngbanwe

Ingsdọ aka na ntị

N'ime ndị ọrịa nwere ọrịa mellitus ma ọ bụ ọrịa obi, ọ dị mkpa iji belata dose ahụ na mbido ọgwụgwọ n'ihi nkwalite nke metabolism dị ala.

Ekwesịrị ịhụ ndị ọrịa nwere hypoadrenocorticism ọzọ na adrenocorticoids tupu ịmalite ọgwụgwọ na levothyroxine.

Mkparịta ụka ga-ekwe omume

Ọgwụ ịgwụ ọgwụ nke na - egbochi mgbochi protein n'ọrịa (glucocorticoids, salicylates na fentoin) nwere ike ime ka ọ dị mkpa ị takeụ ọgwụ dị elu levothyroxine ma ọ bụ mee ka oriri ahụ dị elu.

Usoro ogwu ozo

Achọpụtaghị Triiodothyronine maka nchịkwa n'ihi na ọ nwere ọkara ndụ dị ala ma o yikarịrị ka ọ na-akpata hyperthyroidism iatrogenic.