Aspirin Cardio

Aha mba ofesi - acidum acetylsalicylicum.

Ngwakọta na ụdị ntọhapụ. Ihe na-arụ ọrụ bụ acetylsalicylic acid. Mbadamba 0.1 g ọ bụla 20 PC. na ngwugwu.

  • Omume ọgwụ
  • Ihe ngosi maka ojiji
  • Ihe ngbanwe
  • Nsonaazụ
Omume ọgwụ. O nwere antipyretic, mgbochi mkpali na analgesic. Na-ebelata nchịkọta platelet, na - egbochi ikechi ọbara.

Usoro usoro onunu ogwu. Maka ụmụaka na-erubeghị afọ 2, dọkịta na-ahọrọ usoro ọgwụgwọ ahụ iche iche. Otu mkpụrụ maka ụmụaka dị n’agbata afọ abụọ na atọ - 1 mbadamba ihe, site na 4 ruo afọ 6 - mbadamba abụọ, site na afọ asaa ruo afọ 9 - mbadamba atọ. Otutu oru - otu ugboro ugboro 1-3 kwa ụbọchị. Ogologo oge ọgwụgwọ bụ izu 1-2.

Mmetụta akụkụ. Site na iji ogologo oge, ọgbụgbọ, isi ọwụwa, tinnitus, adịghị ike, ọgbụgbọ, anorexia, mgbu epigastric, afọ ọsịsa enwere ike. N'ọnọdụ ụfọdụ, iji ogologo oge nke ọnụọgụ dị elu, ọnya na ọnya afọ nke eriri afọ, ọbara ọgbụgba site na eriri afọ, mmeghachi ahụ nfụkasị (ọnya anụ ahụ, ọnya Quincke, bronchospasm), na-arụ ọrụ na-arụ ọrụ na-arụ ọrụ, nke na-adịru nwa oge na ọrụ nke ịba ọcha n'anya na ọbara ọbara, ọ na-adịkarị obere ka ọ bụrụ ụbụrụ. .

Contraindications mgbe ị na-ewere Aspirin 100. Ọrịa ọnya afọ na ọnya afọ na -akasị njọ, "aspirin" asthma, ọnụnọ nke ihe na-egosi urticaria, rhinitis "nke ejiri ọgwụ acetylsalicylic acid na ọgwụ mgbochi mbufụt, hemophilia, hemorrhagic diathesis, hypoproth, hypoproth, hypopromipe ọgwụ ọjọọ.

Ntụziaka pụrụ iche. Ejiri ọgwụ ahụ jiri nlezianya mee ihe banyere glucose-6-phosphate depadrogenase ụkọ, ọrụ akụrụ na / ma ọ bụ ọrụ imeju, n'ime ndị ọrịa nwere data anamnestic na mbuze na ọnya afọ na ọbara ọgbụgba site na eriri afọ, yana ndị ọrịa nwere mgbaàmà nke dyspeptik. Acetylsalicylic acid na-akwalite ọrụ nke heparin, anticoagulants na-apụtaghị ìhè, ndị nnọchi ọgwụ antidiedi. Ekwesighi iji ọgwụ a mee ihe n'otu oge iji ọgwụ mgbochi mkpali, ọgwụ methotrexate. Ọgwụ na-ebelata ịdị irè nke spironolactone, furosemide, ọgwụ na-ewepụ uric acid.

Emeputa. Bayer, Germany.

Iji ọgwụ Aspirin 100 mee ihe naanị dị ka dọkịta si kọwaa, a na-enye nkọwa maka ntụnye!

Kedu ọgwụ obi dị ize ndụ maka mmadụ?

Ngwakọta na ụdị ntọhapụ

Otu mbadamba nke ASPIRIN CARDIO nwere acetylsalicylic acid 100 mg ma ọ bụ 300 mg dị ka ihe na-arụ ọrụ, ndị nweburu: cellulose ntụ ntụ, ọka ọka, shei: methaclates acid na ethyl acrylate copolymer 1: 1 (Eudragit L30D), polysorbate 80, sodium lauryl sulfate, talc, citethyl citrate.

Otu ọgwụ Pharmacotherapeutic: ọgwụ mgbochi mkpali na - abụghị steroidal (NSAIDs).

Omume ọgwụ

E gosipụtara ya site na nsonaazụ acetylsalicylic acid (ihe na-arụ ọrụ) nwere n'ahụ ahụ. Aspirin Cardio bụ otu nke ọgwụ mgbochi mkpali na - anaghị egbochi steroidal (NSAIDs). A kọwara mmetụta ya n'ahụ ahụ site na ikike igbochi prostaglandinsynthetase, enzyme nke metụtara na biosynthesis nke prostaglandins.

Site na igbochi imepụta homonụ mbufụt (prostaglandins), Aspirin Cardio nwere mmetụta, antipyretic, mgbochi mkpali. Aspirin Cardio na-eme ka a ghara ikpocha akwukwo (clumping) na ihe ndi a na - ara aru nke platelet. Nke a bụ n'ihi mgbochi nke thromboxane biosynthesis nke A2 na platelet. Mgbe ị takingụchara ọgwụ Aspirin Cardio, a na-achọpụta nsonaazụ antiplatelet n'ime otu izu (ọ naghị ekwupụta na ụmụ nwanyị karịa ụmụ nwoke).

Ihe ngosi maka ojiji

A na-eji ọgwụ aspirin Cardio eme ihe n'oge ọgwụ prophylactic nke ọnọdụ ndị dị otú a:

  • nnukwu myocardial infarction na ọnụnọ ihe ndị dị ize ndụ (dịka ọmụmaatụ ọrịa shuga, hyperlipidemia, ọbara mgbali elu,
  • oke ibu, ise anwuru, ime agadi) na infarction ugboro ugboro.
  • ọrịa strok (gụnyere chespep na ndị ọrịa nwere ọrịa ọgaghị adị).
  • ọghọm ọria ụbụrụ.
  • thromboembolism mgbe ọwachara ya na ọgwụ ndị na-emetụta mmụọ (dịka ọmụmaatụ akwara ọbara na -akpọ grafting, carotid artery endarterectomy, arteriovenous shunting, carotid artery angioplasty).
  • omimi thrombosis na thromboembolism nke akụkụ akwara umeji yana alaka ya (dịka ọmụmaatụ, na-enwe ike ịgwụ ike ogologo oge n'ihi oke ịwa ahụ).
  • enweghi ike angina pectoris.

A na-eji Aspirin Cardio eme ihe n'ọtụtụ ọgwụgwọ nke ọrịa vaskụla n'ihi ikike nke ọgwụ iji gbochie nchịkọta platelet. Ọgwụ na-enyekwa aka n’ịnye ọgwụ analgesic na antipyretic, na -ebelata usoro mkpali.

Ntụziaka maka ojiji

Mbadamba ụrọ aspirin dị ka ntuziaka maka ọrụ ka akwadoro ka a ga-esi jiri otu ugboro n'ụbọchị tupu nri, were mmiri sachaa ya. Ọgwụ dị mma maka iji ogologo oge, dọkịta kpebiri.

  • Iji gbochie nkụchi obi, nkwụchi ma ọ bụ enweghị angina, a na-eji ọgwụ ahụ na 100-300 mg kwa ụbọchị.
  • Iji gbochie ọrịa strok na ihe mberede ụbụrụ, yana mmepe nke thromboembolism n'oge oge ịwa ahụ, a na-ewere ọgwụ ahụ 100-300 mg kwa ụbọchị.
  • N'oge mgbochi bụ isi nke nkụchi obi, a na-a theụ ọgwụ ahụ na 100 mg kwa ụbọchị ma ọ bụ 300 mg kwa ụbọchị.
  • Iji gbochie akwara thrombosis na thromboembolism miri - 100-200 mg kwa ụbọchị ma ọ bụ 300 mg kwa ụbọchị.
  • Site na mmepe nke angina na-akwụghị chịm, a na-atụ aro ọgwụ ahụ 100-300 mg. Ọ bụrụ na ị na-eche obi nkụchi dị ukwuu, onye ọrịa ahụ kwesịrị iburu ọgwụ mbụ ozugbo ị nwere ike. Ekwesịrị ị cheụ ọgwụ ahụ iji mee ka ọ gbasie ike iji mee ka usoro ngụkọta ahụ belata ma nyekwa ọgwụgwọ ọgwụgwọ.

Ọ bụrụ n ’ịwụsị ọgwụ a, e kwesịrị iwere ọgwụ aspirin ngwa ngwa o kwere omume, a ga-eburu ọchịchị ọzọ n’ụzọ ọ bụla, naanị na ị ga-egbu oge iwere mbadamba ihe furu efu ma ọ bụrụ na oge ị takingụ ọgwụ ahụ kwesịrị ekwesị dịka usoro ahụ si dị.

Hụrụ onye iro a swornụrụ iyi MUSHROOM nke mbọ! A ga-asacha mbọ gị na ụbọchị 3! Were ya.

Kedu otu esi eme ka nrụgide olu ike ngwa ngwa mgbe afọ 40 gasịrị? Ntụziaka ahụ dị mfe, dee ya.

Ike gwụrụ ọbara? E nwere ụzọ mgbapụ! Enwere ike ịgwọ ya n’ụlọ n’ụlọ ụbọchị ole na ole, ịkwesịrị.

Banyere ọnụnọ ikpuru na-ekwu ODOR site n'ọnụ ya! Otu ugboro n'ụbọchị, aụọ mmiri nwere mmiri iji ..

Nsonaazụ

Mgbe ị na-a theụ ọgwụ Aspirin Cardio, ọ dị mkpa ịlele usoro onodu ogwu echere na ntuziaka maka ojiji ma ọ bụghị mmeghachi omume ndị a nwere ike ịmalite:

  1. Usoro nke Hematopoietic: mbelata nke ọnụ ọgụgụ ọbara ọbara ọbara, mbelata nke ọnụ ọgụgụ leukocytes, mmụba nke ọnụ ọgụgụ eosinophils, mmụba nke ọnụ ọgụgụ nke platelet, ọdịdị nke imi afọ, ọdịdị nke ọbara ọgbụgba, ọdịdị nke ọbara ọgbụgba, ọdịdị nke ọbara ọgbụgba, ọdịdị nke ọbara ọgbụgba.
  2. Sistem na akụkụ ụjọ: isi ọwụwa, isi ọwụwa,
  3. Usoro ure: mbelata arụmọrụ akụrụ,
  4. Usoro iku ume: akwara umeji, ụkwara, edere,
  5. Usoro nri: ịmịchapụta ahụ, nsogbu akwara, agụụ nri, nri afọ, ọnya afọ, ọnya afọ,
  6. Imebi akpụkpọ ahụ: urticaria, thrombocytopenic purpura, itching nke anụ ahụ, ọrịa dị iche iche.

Na mgbakwunye, iji acetylsalicylic acid na-eme ka ohere ọbara ọgbụgba dịkwuo ike. N'ọnọdụ ndị na-adịghị ahụkebe, mgbe ị na-a Asụ ọgwụ Aspirin Cardio, a na-achọpụta mmụba nke ọrụ transminases imeju, mmepe nke bronchospasm.

Ihe ngbanwe

Ojiji nke ọgwụ chọrọ nnabata akaụntụ na nyocha nke contraindications iji gbochie ọnọdụ ndị na-eyi ndụ egwu. Ndị a gụnyere:

  • Anwụ ụkwara ume ọkụ site na ịla salicylates na NSAID ndị ọzọ,
  • ihe nkwonkwo nke mbufụt ankwarahu, polyposis nke imi na nke paranasal sinuses na nnagide nke ASA,
  • mbuze na ọnya afọ nke eriri afọ na akwara ogbo,
  • eriri afọ,
  • hemorrhagic diathesis,
  • jikọtara ọnụ na iji methotrexate na dose nke 15 mg kwa izu ma ọ bụ karịa,
  • ime (M na III trimesters),
  • lactation
  • ụmụaka na ndị na-eto eto (ruo afọ 18),
  • nnukwu nsogbu gbasara akụrụ (CC na-erughị 30 ml / min),
  • ọrịa imeju siri ike (klas B na nke dị elu n'ihe banyere nwatakịrị-Pugh),
  • NYHA Klas III-IV ọrịa obi na-adịghị ala ala,
  • hypersensitivity na acetylsalicylic acid, ndị nweburu na mejupụtara ọgwụ ahụ na NSAID ndị ọzọ.

A na - achọpụta ihe ngosipụta na - adịghị mma mgbe ị na - eji ọgwụ Aspirin ugboro ugboro karịa ịdoụbiga mmanya ókè na ị medicationụ ọgwụ n'echeghị ọgwụ mgbochi.

Dodoụbiga ya ókè

Icyxụbiga mmanya ókè (na-amalite mgbe ị na-a ASụ ọgwụ ASA na ihe karịrị 100 mg / n'arọ / ụbọchị karịa ụbọchị 2) nwere ike ịpụta site na iji ọgwụ ọgwụ egbu egbu ogologo oge dịka ọgwụ ị improụ ọgwụ na-adịghị mma (na-egbu egbu egbu) ma ọ bụ otu ihe ọghọm ma ọ bụ nchịkwa nke nchịkwa ọgwụ na-egbu egbu. okenye ma ọ bụ nwa (nnukwu mmenaanya).

E nwere ogo atọ ogo ọnọdụ ahụ bụrụ na ị doụbiga ya ókè.

  1. Ogo mbu weputara n’otu ọgwụ Aspirin Cardio erughi 0.15 g / kg nke ibu ndidi. Ọrịa: dyspepsia, isi ọwụwa, ọgba aghara a na-ahụ anya, ahụ ọkụ.
  2. Ogo nke abuo putara n’otu ogwu Aspirin Cardio site na 0.15 rue 0.3 g / kg nke ibu ndidi, nke ato n’ime ihe kariri 0.3 g / kg.
  3. N'ihe banyere nsi, a na-eji ọnya afọ na ọnya, na-a usedụ ọgwụ, a na-arụ ọgwụgwọ symptomatic. Ọ dị mkpa ijikwa pH nke ọbara na ntinye nke sodium bicarbonate, n'ihe banyere ịkpa ókè homeostasis n'akụkụ acidic. A na-eji ntụgharị ahụ na ikuku nke ikuku eme ihe n'ọnọdụ siri ike, dị ka ihe na-egosi.

Dabere na data nlekota, nkezi ọnụahịa nke mbadamba ASPIRIN CARDIO na ụlọ ahịa ọgwụ (Moscow) bụ 78 rubles.

Ihe analogues Aspirin Cardio bu Trombo Ass, Avix, Axanum, Agrenox, Brilinta, Gendogrel, Disgren, Ilomedin, Ipaton, Kropired, Cardogrel, Clopidal, Lopired, Pingel, Plavix, Platogril, Trombonet, Effient. Ọtụtụ mgbe ọnụahịa analogues dị iche na ụgwọ ọgwụ mbụ.

Ntị: iji ọgwụ ike ana-ekwenye ekwenye na dọkịta na-ahụ maka ịga.

Mpempe usoro onunu ogwu

Mkpokọta osisi akpọrọ Enteric 100 mg na 300 mg

Otu mbadamba ihe

ike ihe - acetylsalicylic acid 100 mg ma ọ bụ 300 mg,

ndị mgbe ochie: cellulose ntụ ntụ, stachi ọka, eudragit L30D, polysorbate 80, sodium lauryl sulfate, talc, citethyl citrate.

Gburugburu, biconvex, dịtụ njọ, mbadamba ihe na-acha ọcha na -eche ọnụ ọnụ, na kink - uka na-acha ọcha, nke gbara gburugburu otu agba

Ngwongwo ogwu

Mlọ ọgwụ

Mgbe nchịkwa ọnụ gasịrị, acetylsalicylic acid (ASA) na-abanye ngwa ngwa ma zuo ezu na ngọngọ nri.

N'ime oge a na-eme ka mmiri ahụ ma ozugbo ọ gasịrị, acetylsalicylic acid na-agbanye n'ime metabolite nke bụ isi - salicylic acid.

A na-enweta mkpokọta kachasị nke acetylsalicylic acid na plasma ọbara mgbe nkeji 10-20 gasịrị, mkpokọta kachasị nke salicylic acid na awa 0.3-2.

N'ihi eziokwu na mkpuchi mkpụrụ ndụ nke mbadamba ụrọ nke Aspirin cardio® na-eguzogide acid, ihe anaghị arụ ọrụ anaghị ahapụ n'ime afọ, mana na gburugburu alkaline nke eriri afọ. N'ihi nke a, nnabata acetylsalicylic acid na-egbu oge site na awa 3-6 ma e jiri ya na mbadamba anaghị etinye mkpuchi mkpuchi.

Acetylsalicylic na salicylic acid na-egbochi protein ndị dị plasma ma na-ekesa ngwa ngwa.

A na-agbanye salicylic acid na mmiri ara ara ma na-agafe ihe mgbochi placental.

Salicylic acid bụ metabolized kachasị na imeju ya na nguzobe nke metabolites - salicylurate, salicylophenol glucuronide, salicylacyl glucuronide, gentisic na gentizuric acid.

Mgbakwunye nke salicylic acid bụ ọgwụ dabere na ya.

Ndụ ọkara ahụ mgbe ị theụrụ ọgwụ ahụ na obere doses bụ awa 2-3, mgbe ị takingụ ọgwụ ahụ na oke doses bụ awa 15. Salicylic acid na metabolites ya bụ akụrụ na-akachasị akụrụ.

Mlọ ọgwụ

Usoro nke acetylsalicylic acid dabere na mgbochi a na-agbanwe agbanwe nke cyclooxygenase (COX-1), n'ihi nke a na-egbochi mkpokọta thromboxane A2 ma na-ebelata nchịkọta platelet. A na-ekwuputa mmetụta antiplatelet na platelet, ebe ọ bụ na ha enweghị ike ịmegharị cyclooxygenase.

A kwenyere na acetylsalicylic acid nwere usoro ndị ọzọ maka igbochi nchịkọta platelet, nke na-agbasa obosara ya n'ọrịa ọrịa vaskụla dị iche iche.

Acetylsalicylic acid bụ otu nke ọgwụ mgbochi mkpali na - abụghị ọgwụ steroidal, yana ọ na - enwe mmetụta, antipyretic na ọgwụ mgbochi.

A na-eji doses dị elu iji belata ihe mgbu na obere febrile ọnọdụ, dị ka oyi na flu, iji belata ahụ ọkụ, belata olu na nkwonkwo mgbu, yana maka ọrịa na-efe efe na-adịghị ala ala dịka ọrịa ogbu na nkwonkwo, osteoarthritis na ankylosing spondylitis.

Usoro onunu ogwu na nhazi

Maka nchịkwa ọnụ.

Ekwesịrị iburu mbadamba mkpụrụ osisi kaadị dị n'ime, nke a na-etinye n'ime ya tupu nri amalite inwe ọtụtụ mmiri.

Iji belata ihe egwu ọnwụ n’obere ndị ọrịa nwerennukwu myocardial infarction

Ọgwụ mbụ nke 100-300 mg (a ga-ata ata mbadamba mbụ maka nnabata ngwa ngwa) onye ọrịa ahụ kwesịrị ịnwe ya ozugbo enwere ike mgbe enwere enyo nke mmepe nke nnukwu myocardial infarction.

N'ime ụbọchị iri atọ na-esote mgbe mmepe nke infarction myocardial, a kwesịrị idobe otu nha nke 100-300 mg / ụbọchị.

Mgbe ụbọchị iri atọ gasịrị, ekwesịrị ịtụle mkpa ọgwụgwọ ọzọ iji gbochie mmepe nke infarction ugboro ugboro.

Iji belata ihe ize ndụ nke ọrịa na ọnwụ na ndị ọrịa mgbe infarction myocardial

Maka mgbochi nke ọnya afọ

Iji belata ihe ize ndụ nke TIA na ọrịa strok na ndị ọrịa nwere TIA

Iji belata ọrịa na ọnwụ na angina kwụsiri ike ma kwụsie ike

Maka mgbochi nke thromboembolism mgbe ịwa ahụ na ọgwụ vaskụla anụ ahụ na-emetụta

Maka mgbochi nke thrombosis nke akwara dị omimi na thromboembolism pulmonary

100-200 mg / ụbọchị ma ọ bụ 300 mg kwa ụbọchị

Iji belata ihe egwu nke infarction achoro nke dị ala

100 mg kwa ụbọchị ma ọ bụ 300 mg kwa ụbọchị.

Nsonaazụ

Nsonaazụ ndị a edepụtara n'okpuru sitere na data sitere na akụkọ mkpesa na azụmaahịa na ahụmịhe iji ụdị ọgwụ mgbu Aspirin, gụnyere ụdị ọnụ maka obere ọgwụgwọ na obere oge.

N'akụkụ a, ngosipụta ha ugboro ugboro dabere na otu nke CIOMS III agaghị ekwe omume.

- dyspepsia, afọ na-egbu mgbu na mpaghara eriri afọ

- mbufụt nke eriri afọ, ọnya nke akpụkpọ ahụ nke mucous nke afọ na duodenum (nke adịkarịsịrị ike na-eduga n'ọbara afọ na perforations nwere akara kwekọrọ na akara ụlọ nyocha).

Ọ na-adịkarịke - ọ na-esi ike:

- Ọnọdụ ikpere ọbara ọgbụgba, dịka ọbara ọgbụgba n'ime eriri afọ, ọbara ọgbụgba ụbụrụ (ọkachasị ndị ọrịa nwere oke mgbali ọria na / ma ọ bụ na-anabatakwa ọgwụgwọ na ọgwụ anticoagulant), nke ụfọdụ nwere ike ibute ndụ egwu.

- mmeghachi omume hypersensitivity siri ike, gụnyere ujo anacticlactic

- nkwụsi umeji imeju ya na mmụba nke “akụrụ” transaminases

Na ugboro-amaghị

ọbara ọgbụgba, dịka ọbara ọgbụgba, hematomas, epistaxis (epistaxis), ọbara urogenital, ọgbụgba na-agba ọbara.

- hemolysis na hemolytic anaemia n'ime ndị ọrịa nwere ụdị glucose-6-phosphate dehydrogenase siri ike.

- arụrụ ọrụ na-arụ ọrụ na arụ yana nnukwu akụrụ akwara

- mmeghachi omume hypersensitivity na ngosipụta ndị dị na ya na ụlọ nyocha (ọrịa asthmatic syndrome), mmeghachi azụ na-agafeghị oke site na anụ ahụ, akụkụ okuku ume, akụkụ eriri afọ na usoro obi, gụnyere ahụ ọkụ, urticaria, edema, itching skin, rhinitis, edema akpụkpọ ahụ imi, mkpụrụ ndụ iku ume)

- ure na ịkwa ntị na ntị, nke nwekwara ike ịbụ ihe ịrịba ama nke ịdoụbiga ọgwụ ókè.

Mkparịta ụka ọgwụ ọjọọ

Methotrexate na 15 mg / izu ma ọ bụ karịa

Site na iji ASA na oge methotrexate, mmụba na-egbu egbu nke methotrexate na-abawanye n'ihi eziokwu ahụ bụ na NSAIDs na-ebelata mkpụkọ nke methotrexate, yana salicylates, karịchaa, chụpụ ya na njikọ na protein protein.

Mgwakọta chọrọ ịkpachara anya

Ibuprofen nwere iji ya mee ihe na ASA na-emegide ezi mmetụta ya na platelet.

N'ime ndị ọrịa nwere oke ihe ibute ọrịa obi, ojiji nke ibuprofen na ASA na-eduga n'otu oge na nsonaazụ obi ya.

Ọgwụ anticoagulants, thrombolytic na ọgwụ antiplatelet ndị ọzọ

E nwere ihe ize ndụ nke ọbara ọgbụgba.

Ndị NSAID ndị ọzọ nwere salicylates dị elu (3 g / ụbọchị ma ọ bụ karịa)

N'ihi mmekorita nke ihe a, ihe ọghọm nke ọnya afọ nke mucosa na ọbara ọgbụgba na-abawanye.

Nhọrọ Serotonin Reuptake Inhibitors

N'ihi mmekorita nke ihe a, ihe ọghọm nke ọbara ọgbụgba site na eriri afọ nke elu na-abawanye.

Site n'ibelata mkpụkọ akwara, ASA na-eme ka mkpocha digoxin na plasma ọbara.

Ndị ọrụ Antidiabetic, dịka insulin, sulfonylureas

Ngwọta dị elu nke ASA na-akwalite mmetụta nke ọgwụ ọgwụ hypoglycemic n'ihi mmetụta hypoglycemic nke acetylsalicylic acid na nchụpụ nke usoro sulfonylurea site na nkwukọrịta na protein protein plasma.

Diuretics yana otutu nke ASA

Enwere mbelata nke ịkpụcha ọnụ nke ụwa n'ihi mbelata nke njikọta nke prostaglandins n'ime akụrụ.

Sisiko glucocorticosteroids (GCS), ma ewezuga hydrocortisone, ejiri mee ihe maka ọgwụgwọ ọgwụgwọ maka ọrịa Addison.

Site na usoro ọgwụgwọ corticosteroid, ọkwa nke a na-eme ka salicylates n'ọbara na-ebelata ma enwere ihe ize ndụ nke ịmalite ịdoụbiga ókè nke salicylates mgbe ịkwụsị ọgwụgwọ, ebe ọ bụ na corticosteroids na-eme ka akụkụ nke ikpeazụ kwụsị.

Angiotensin-na-agbanwe enzyme (ACE) na-egbochi ndị ọrụ yana usoro ọnụọgụ dị elu nke ASA

Enwere mbelata nke mkpokọta ụwa ọnụ n'ihi mgbochi nke prostaglandins nwere mmetụta vasodilating, n'otu aka ahụ, adịghị ike nke mmetụta hypotensive.

Xic acidụ ahụ acidproproic na-abawanye n'ihi nnabata site na nkwukọrịta na protein protein plasma.

Enwere ọghọm mbibi nke eriri afọ na-abawanye n'oge ọbara ọgbụgba n'ihi nkwalite mmekọrịta nke ASA na ethanol.

Ọgwụ Uricosuric dịka benzbromaron, probenecid

Mmetụta uricosuric belatara n'ihi asọmpi akwara renal tubular kpochapụ uric acid.

Ntụziaka pụrụ iche

Ekwesịrị iji ọgwụ ọjọọ mee ihe na ọnọdụ ndị a:

- na hypersensitivity na analgesics, mgbochi mkpali, ọgwụ rheumatic ọgwụ na ụdị ndị ọzọ nke allergies.

- ọnụnọ nke akụkọ ntolite ọnya afọ nke eriri afọ, gụnyere ọrịa ọnya afọ na-adịghị ala ala ma ọ bụ nke ugboro ugboro.

- Mgbe ejiri ọgwụ iji ọgwụ eme ihe (Lee mpaghara “Mmekọrịta Ọgwụ”)

- n’ime ndị ọrịa nwere nsogbu gbasara akụrụ ma ọ bụ ọrụ akwara (dịka ọmụmaatụ, na ọrịa akụrụ, akwara obi na -akpọ, na-ebelata ọbara n’arịa, nnukwu ịwa ahụ, sepsis ma ọ bụ ọbara ọgbụgba), ebe ọ bụ na acetylsalicylic acid nwere ike nwekwuo ike ibute mmebi akụrụ ma ọ bụ nnukwu. gbasara akwara

- n'ime ndị ọrịa na - ata ahụhụ glucose-6-phosphate dehydrogenase (G6FD), acetylsalicylic acid nwere ike ime ka mmepe nke hemolysis ma ọ bụ ọrịa hemolytic. Ihe ndị nwere ike ibute oke nsogbu nke hemolysis gụnyere, dịka ọmụmaatụ, oke oke ọgwụ ahụ, ahụ ọkụ, ma ọ bụ ọnụnọ nke nnukwu ofufe ọrịa.

- bụrụ na arụ ọrụ imeju na-arụ ọrụ

Ibuprofen nwere ike igbochi mmetụta mgbochi nke ASA na nchịkọta platelet. Ndị ọrịa na-anata ọgwụgwọ ASA ma na-ewere ibuprofen maka enyemaka mgbu kwesịrị ịgwa dọkịta ha.

ASA nwere ike ịkpali bronchospasm, ma na-ebute ọgụ nke ụkwara ume ọkụ na mmeghachi ume mmụọ ndị ọzọ. Ihe ndị dị ize ndụ bụ akụkọ ihe mere eme nke ashma, fever fever, polyposis nasal, ọrịa na-adịghị ala ala nke akụkụ okuku ume, yana mmeghachi ahụ nfụkasị ihe ndị ọzọ (dịka ọmụmaatụ, mmeghachi ahụ anụ ahụ, itching, urticaria).

N'ihi mmetụta inhibitory na platelet, iji ọgwụ aspirin nwere ike ịnwe ya na ihe nwere ike ibute ọbara ọgbụgba. N'ihi ike a ga-ebelata nchịkọta platelet, nke dịgidere ruo ọtụtụ ụbọchị mgbe ị theụsịrị ọgwụ ahụ, acetylsalicylic acid nwere ike ibute ọbara ọgbụgba n'oge yana ịwa ahụ (gụnyere obere ọrụ ịwa ahụ, dị ka mmịpụta ezé).

Ọbara ọgbụgba nwere ike ibute mmepe nke ajọ ọrịa ma ọ bụ ọrịa postemorrhagic / ụkwara ọrịa na-adịghị ala ala (dịka ọmụmaatụ, n'ihi microbleeding latent) yana akara ngosipụta na akara ụlọ ọrụ kwekọrọ, dị ka asthenia, pallor nke anụ ahụ, hypoperfusion.

ASA na doses dị ala na-ebelata excicion nke uric acid, nke nwere ike ịkpasu mmepe nke gout n'ahụ ndị mmadụ nwere nsogbu.

Ojiji ụmụaka

Enwere mmekọrịta n'etiti ị Asụ ọgwụ Aspirin na mmepe nke ọrịa Reye mgbe ejiri ya na ụmụaka nwere ọrịa nje ụfọdụ. Enwere ike ịbawanye ihe egwu ahụ yana ojiji ọgwụ jikọtara ASA, mana achọpụtaghị mmekọrịta na-akpata. Mmepe nke ọgbụgbọ na-adịgide adịgide na ọrịa ndị a nwere ike ịbụ ihe ịrịba ama nke ọrịa Reye.

Ọrịa Reye bụ ọrịa na-anaghị ahụkebe nke na-emebi ụbụrụ na imeju ma na-egbu egbu.

Na nke a, aspirin kadio Ekwesighi iji ya na umuaka na ndi na-eto eto n’agbata afọ 18, belụsọ ma egosiri ya.

Jiri n’oge ime

Inhibido njikọta nke prostaglandin nwere ike inwe mmetụta dị njọ na afọ ime ya na mmepe nke ẹmbrayo ma ọ bụ nwa ebu n’afọ. Ihe omuma sitere na ihe omumu ihe banyere oria na egosiputa ohere di elu nke ibupute ihe ojoo na mmebi site na iji ihe ndi mmadu na egbochi oria prostaglandin. N'otu oge ahụ, ekwenyere na ihe ize ndụ ahụ na-abawanye site na ịba ụba nke oge yana ọgwụgwọ. Ihe dịnụ ekwuputaghị mmekọrịta ọ bụla n'etiti iji acetylsalicylic acid na ohere dị ukwuu nke njedebe nke ime oge. Enwere ihe omuma banyere oria ojoo di iche-iche banyere nmeghari nke umu mmadu adighi aghota ihe obula, ihe isi ike nke imeputa ihe ojoo bu - enweghi ike ichipu odida. Ojiji nke ASA na mmalite afọ ime (ọnwa 1-4) n'ime ụmụ nwanyị / ụmụaka 14.8 ekpugheghị mkpakọrịta ọ bụla na ụba ugboro.

Ihe omumu omumu omumu egosila ututu omumu. Egosiputaghi oge a ga - ejiko acetylsalicylic acid n'ime oge ato na nke abuo nke ime ime rue rue mgbe ekwuputara ya.

N'iburu nke a n'uche, n'ime oge nke mbụ na nke abụọ nke afọ ime, Aspirin kadiona pacenti iri ogwu g’eji mee ya bu mgbe onye dọkịta nyochachara nke oma ihe di nkpa / uru di ya.

Mgbe ị na-eji ọgwụ nwere nwanyị Acetylsalicylic acid n’oge ịtụrụ ime, ma ọ bụ n’ime oge nke mbụ na nke abụọ nke afọ ime, ọ dị mkpa iji ọgwụ dị ala kachasị dị ala wee mee obere ọgwụgwọ.

N'ime oge nke atọ nke afọ ime, ihe niile prostaglandin na - egbochi ihe nwere ike ibute nwa ebu n’afọ:

Ọkpụkpụ akpịrị cardiopulmonary (ya na mmechi nke nkuku botallal na ọbara ọgbụgba)

gbasara akụrụngwa gbasara akwara, nke nwere ike ịga n'ihu na mpụta akwara na oligohydramnios,

N'ime nne na nwa ebu n'afọ na njedebe nke afọ ime:

mmụba ọ ga - abawanye n'oge oge ọgbụgba, nsonaazụ antiplatelet, nke nwere ike ịme ọbụlagodi obere obere

belata mmebi nke akpanwa, nke nwere ike iduga mmadụ n'ọrụ ma ọ bụ ogologo oge

N'akụkụ a, ASA bụ contraindicated maka iji nke atọ nke afọ ime.

Jiri n'oge a na-asa ahụ

A na-ewepụta Salicylates na metabolites ha na obere obere mmiri ara. Mfe nke salicylates n'oge a na-enye nwa anaghị achọ ịkwụsị ị ofụ ara. Agbanyeghị, mgbe dọkịta depụtara iji ọgwụ ahụ ogologo oge ma ọ bụ na-a acụ ọgwụ acetylsalicylic acid, a ga-akwụsị inye ya ara.

Akụkụ nke nsonaazụ ọgwụ ahụ nwere ike ịnya ụgbọ ma ọ bụ usoro nwere ike ibute

Ideringtụle nsonaazụ ndị ọ bụla nwere ike ịdị, dị ka nkụda mmụọ, a ga-akpachara anya mgbe ị na-anya ụgbọala ma ọ bụ igwe nwere ike ịdị ize ndụ.

Ahapụ Gị Ikwu