Ọgwụ Farmasulin: ntuziaka maka ojiji > Ọgwụgwọ na mgbochi

Farmasulin® N NP na Farmasulin® N 30/70 bụ nkwadebe nke insulin mmadụ na-enweta site na iji teknụzụ DNA recombinant. Nke ikpeazụ a nwere njirimara nke insulin. Ọgwụ na-achịkwa mmezi carbohydrate na akwara. Belata shuga ọbara. Ha na-enye aka ịkwalite njem ike nke carbohydrates na amino acids n'ime oghere intracellular, na-ebelata lipolysis, na-akpali njikọ nke RNA na protein, yana ịgbalite njikọta glycogen. Ọgwụ ndị ahụ na-abawanye usoro nke potassium n'ime sel site na oghere pericellular, nke na-enyere aka belata ogo dipoolic myocardial depolarization nke na-eme na cardiopathy yana dịka mmetụta n'akụkụ mgbe ị na-eji digitalis, GCS na catecholamines.
Mmalite nke mmetụta bụ 1 elekere mgbe nchịkwa nke Farmasulin® N NP ma ọ bụ nkeji 30 mgbe nchịkwa nke Farmasulin® H 30/70. A na-ahụkarị ntinye uche na ọgwụgwọ kachasị elu n'etiti elekere 2 na 8 mgbe ị na-eji Farmasulin® N NP ma ọ bụ n'agbata awa 1 na 8.5 mgbe ị na-eji Farmasulin® H 30/70. Ogologo oge nke ịnọgide na-etinye ịgwọ ọrịa bụ 18-20 awa ma ọ bụ awa 14-15, n'otu n'otu.

Ihe ngosiputa maka iji ọgwụ ọgwụ Farmasulin

Ọrịa shuga na-arịa insulin na-adabere na ọrịa shuga mellitus (ụdị nke II), ọ bụrụ na ọ gaghị ekwe omume nweta nkwụghachi nke ọrịa ahụ site na iji nri na ọgwụ ọnụ hypoglycemic ọgwụ. Typedị ọrịa shuga ọ bụla gbagwojuru anya site na ọrịa, ọrịa anụ ahụ na-adịghị agwọ, gangrene, ọrịa obi na-ezighi ezi na mkpọchi, retinopathy na-aga n'ihu, ọrụ ịwa ahụ na ndị ọrịa nwere ọrịa shuga, ketoacidosis, precoma na coma, iguzogide sulfonylureas, oge ịtụrụ ime na ndị ọrịa ọrịa shuga.

Ojiji ọgwụ Farmasulin

P / c. A na-agha usoro onyonyo na oge nchịkwa iche iche maka onye ọrịa ọ bụla. A na-enye ọgwụ ahụ 1 ma ọ bụ ọtụtụ ugboro n'ụbọchị. Oge dị n'etiti ntụtụ SC na nri iri kwesịrị ịkarị ihe 45-60 nkeji (ọ karịghị nkeji iri atọ mgbe ị na-eji Farmasulin® N 30/70). Iji ọgwụ ọjọọ eme ihe kwesịrị iso onye ọzọ ga-eri ya. Mgbe ị na-ekpebi ọdịnaya calorie nke nri (dịka iwu, kalo 1700-3000), ọ dị mkpa ka ịdị na-eduzi ahụ onye ọrịa, yana ọdịdị nke ọrụ ya. Mgbe ị na-ekpebi usoro ọgwụ mbụ, ọ dị mkpa ka ọkwa nke glycemia na-ebu ọnụ na ụbọchị, yana ọkwa glucosuria n'ụbọchị. Na ngụkọta oge ngụkọta nke ọgwụ ahụ, mmadụ ga-eduzi ya site na nchebara echiche ndị a: ọ bụrụ na ọkwa glycemia karịrị 9 mmol / L, 2-4 IU nke insulin chọrọ maka mgbazi nke ọ bụla 0.45-0.9 mmol / L nke ọbara glucose. Nhọrọ nke insulin nke ikpeazụ ka a na-eme n'okpuru njikwa ọnọdụ nke onye ọrịa yana iburu n'uche glucosuria na glycemia, nke a na-ahụ megide ndabere nke iji ọgwụ ahụ. Dị ka ọ dị, kwa ụbọchị ị theụ ọgwụ ahụ bụ 0-1-1.0 IU / kg body body na ndị okenye na ha ekwesịghị gafere ogo 0.7 IU / kg body body. N'ime ndị ọrịa nwere ọrịa labile nke ọrịa ahụ, n'oge afọ ime, na ụmụaka - mgbanwe nke insulin kwesịrị ịgabiga 2-4 IU kwa 1 ịgba.
Ọkpụkpụ
You gha aghaghi ijide n’aka na eji sirinji mee ihe, nggu akwukwo nke kwekọrọ na ntinye nke insulin. Ekwesịrị iji sirinji nke otu ụdị na ika ya. Enweghị nlebara anya mgbe ị na-eji sirinji nwere ike ibute ịsụ insulin. A na-eme ntụtụ ahụ dị ka ndị a:

Tupu ịnakọta insulin na vial, ọ dị mkpa iji lelee ọnọdụ nke ihe dị n'ime ya. N'ihe banyere ọgba aghara ma ọ bụ ọdịdị nke agba dị elu mgbe edozichara ọdịnaya nke vial ahụ, ekwesighi iji ọgwụ a. Ngwa ngwa tupu ntụtụ, a na-emegharị vial ahụ nkwụchi n’etiti ọbụ aka ka ọgba aghara ya n’ogwe ahihia ahụ wee bụrụ otu.
A na - anakọta insulin site na vial ahụ site na iji ya na irighiri sirinji agịga nke e ji mmanya na-egbu mee ma ọ bụ ihe na-egbu egbu nke ayodiin. Okpomoku nke mmanu insulin kwesiri ino na okpomoku.
Ọ bụrụ na naanị otu ụdị insulin na-eji, yabụ:
- a na-adọta ikuku n’ime sirinji ka ọ baa uru n’ihe insulin chọrọ, ma emesịa wepụta ikuku n’ime vial ahụ,
- sirinji nwere vial a tụgharịrị wee mee ka vial tụgharịa elu ma nwetakwa insulin chọrọ,
- ewepu agịga ahụ na vial. A na-ewepụta sirinji si na ikuku ma na-enyocha izizi nke ọ̀tọ insulin.
Ọ bụrụ na ngwakọta abụọ nke insulin agwakọtara, mgbe ahụ tupu ntụtụ vial ya na nkwụsị insulin (ntụgharị turbid) na-agagharị n’apata aka ka isi ya nwee ike n’oghere nke vial ahụ nile. A na-adọrọ olu nke ikuku n'ime sirinji nke kwekọrọ na ọgwụ achọrọ maka nkwụsị insulin, a na-ewebata ikuku a n'ime oghere yana nkwusioru nke insulin. Wepu agịga ahụ n'ime karama ahụ. Ọzọkwa, a na-adọta ikuku n'ime sirinji ka ọ baa uru ọ̀ chọrọ insulin insulin na-eme ọlị. Tinye ikuku a n'ime karama nwere ngwakọta insulin. A na-atụgharị sirinji na vial ka vial ahụ dị kpodoro isi wee nwetakwa ọgwụ chọrọ insulin insulin na-enyocha. Wepu ikuku si nro ma lelee izizi nke onodu insulin. A na-etinyekwa agịga ahụ n'ime vial ahụ site na nkwụsị nke insulin ma na-anakọta dose ahụ enyere. Wepu ikuku si nro ma lelee uzo ziri ezi. Ọ dị mkpa mgbe niile ịpinye insulin na usoro egosipụtara. Nke a na - eme ka mmelite nke ngwakọta dị nro. Ozugbo emechara arụmọrụ ndị a dị n'elu, a gbanye ya ọgwụ.
Jide akpukpo ahu n’agbata mkpịsị aka gị, gbanye agịga ahụ n’oghere akpụkpọ ahụ n’akuku dị ihe dịka 45 Celsius ma gbanye insulin s / c.
Wepu agịga ahụ ma na-agbanye ebe injection ntakịrị oge ole na ole iji gbochie ọpụpụ nke insulin.
Ọ dị mkpa ka ị gbanwee ebe ntụtụ.

Nsonaazụ nke ọgwụ Pharmasulin

Oge na-adịbeghị anya - lipodystrophy, nguzogide insulin, mmeghachi omume hypersensitivity. Site na ọgwụ insulin ogologo oge na saịtị ịgba agba, enwere ike ịhụ akụkụ nke atrophy ma ọ bụ ọbara mgbali elu nke abụba dị n'okpuru ala. Enwere ike igbochi ihe ịtụnanya ndị a site na-agbanwe agbanwe mgbe niile. Ọ bụrụ na enwere nfụkasị izugbe na ụdị insulin ndị ọzọ na akụkọ ntolite nke onye ọrịa, edepụtara ọgwụ ndị a mgbe enwetasịrị ule intradermal na-adịghị mma. N'ọnọdụ mmeghachi omume nfụkasị, ọ dị mkpa ịnyefe onye ọrịa ahụ n'ụdị insulin ọzọ ma nye ya ọgwụ mgbochi nfụkasị. N'ihe banyere inye insulin ọgwụ ma ọ bụ iri nri, ma ọ bụ mgbatị anụ ahụ, inspoglycemic na-emetụta insulin nwere ike ịmalite. Ọrịa hypoglycemia siri ike na-enweghị ike ịmalite site na iji onye na-arịa ọrịa shuga na-a alcoholụ mmanya. Ọ bụrụ na etinye uche nke glucose na ọbara n'ọtụtụ dị oke elu, ọnọdụ nke ketoacidosis na-arịa ọrịa shuga na-apụta. Ọrịa siri ike nwere ike ịmalite ma ọ bụrụ na onye ọrịa enweta insulin nke obere karịa ka ọ dị mkpa. Enwere ike ime nke a site na ịba ụba nke insulin n'oge ọrịa, imebi nri, nhazi insulin ma ọ bụ insulin nke na-ezughị ezu. Enwere ike ịchọpụta mmepe nke ketoacidosis site na nyocha nke mmamịrị, ebe a na-achọpụta ọdịnaya dị elu nke shuga na ahụ ketone. Nke nta nke nta, na-abụkarị n’ime awa ole ma ole ma ọ bụ ụbọchị ole na ole, ihe mgbaàmà na-apụta dịka akpịrị ịkpọ nkụ, ịba ụba diuresis, agụụ, ike gwụ, anụ ahụ akpọnwụ, miri emi na iku ume. Ọ bụrụ na agwọghị onye ọrịa nọ n'ọnọdụ a, ọ ga - ekwe omume na ọria mamịrị na - ebute ihe na - egbu egbu.

Ntụziaka pụrụ iche maka iji ọgwụ ọgwụ Farmasulin

Na nha nke 4b IU, 1-2 ugboro n'ụbọchị, enwere ike iji ọgwụ nje dịka onye na - anabolic maka mkpochapụ ahụ, furun ụkwara, thyrotoxicosis, atony nke afọ, ịba ọcha n'anya, na ụdị mbụ nke cirrhosis. N'ime omume psychiatric, enyere ya ọgwụ maka ọgwụgwọ na-ewusi mmụọ niile ike. Ejiri ya maka ọgwụgwọ nke ọrịa mamịrị, na mpaghara ịwa ahụ.

Mmekọrịta ọgwụ ọgwụ

Glucagon, diazoxide, ihe ndị sitere na phenothiazine, thiazide diuretics, corticosteroids, homonụ thyroid, mgbochi mkpị na homonụ na-eme ka ike gwụ hypoglycemic mmetụta nke insulin. Mmụba na ogo mmetụta hypoglycemic nke homonụ ga-ekwe omume site na nhazi nke salicylates, guanethidine, MAO inhibitors, oxygentetracycline, na anabolic steroid. Insulin na-abawanye ọgwụ mgbochi ụkwara nta nke PASK. Insulin na strophanthin nwere otu mmetụta na arụ ọrụ na nkwekọrịta na metabolism nke metabolic, n'ihi nsonyerịta nke ibe ma ọ bụ ọbụlagodi mmetụta ha ga-ekwe omume. Na usoro ọgwụgwọ insulin, tupu ịkwaa ọgwụ anaprilin nwere ike ime ka hypoglycemia dị ogologo. Mmanya na-abawanye n’ihe ize ndụ nke ịba ọcha n’anya.

Masdoụ ọgwụ ọgwụ ọgwụ gabigara ókè, ihe mgbaàmà na ọgwụgwọ

Ọ bụ ya zuru oke ma nwekwaa ya. Na-akpata oke hypoglycemic mmetụta. Oriri na-ezughị ezu (ụkọ nri mgbe ọ gbasasịrị insulin), imega ahụ na ị alcoholụbiga mmanya ókè na-eso akpata ya. Karịsịa mgbe ọ nwere ike ime na a labile N'ezie nke ọrịa, na agadi ọrịa, na-arụzi ọrụ ezumike ọrụ. Egosiputara ogwu site na ịcha, ima jijiji na mmeghachi omume ndị ọzọ na -akpata onwe ha, ngwa ngwa iwepu mmụọ. Ọgwụgwọ mejupụtara glucose na - adọ adọ n'ime oge (na mmalite nke hypoglycemia). Iji gbochie hypoglycemia, a na-enye onye ọrịa tii tii ma ọ bụ obere cubes ole na ole. Ọ bụrụ na ọ dị mkpa, a na-eme ntụgharị 40% nke glucose na-agba agba intrauslong ma ọ bụ 1 mg glucagon na-achịkwa intramuscularly. Ọ bụrụ na onye ọrịa ahụ agbakebeghi na coma mgbe ọ mesịrị ọkwa shuga dị n'ọbara, ọ dị mkpa ịnye mannitol ma ọ bụ nnukwu corticosteroids iji gbochie ọrịa ụbụrụ.

Ọnọdụ nchekwa nke ọgwụ Farmasulin

N’ebe gbara ọchịchịrị n ’okpomoku nke 2-8 Celsius С. Ekwenyela insulin gafere oyi ma ọ bụ kpughere ya maka ìhè anyanwụ! Enwere ike idobe vial insulin eji mee ya na n ụlọ okpomọkụ (ruo 25 Celsius) maka izu isii. N'ihe banyere ọgba aghara ma ọ bụ ọdịdị nke agba dị elu mgbe edozichara ọdịnaya nke vial ahụ, ekwesighi iji ọgwụ a.

Aha:

Farmasulin (Farmasulin)

1 ml nke Farmasulin N ngwọta nwere:
Insulin biosynthetic mmadụ (nke teknụzụ recombinant nke DNA mere) - 100 IU,
Ihe ndi ozo.

1 ml nke Pharmulinulin H NP nkwusioru nwere:
Insulin biosynthetic mmadụ (nke teknụzụ recombinant nke DNA mere) - 100 IU,
Ihe ndi ozo.

1 ml nke nkwusioru nke Farmasulin H 30/70 nwere:
Insulin biosynthetic mmadụ (nke teknụzụ recombinant nke DNA mere) - 100 IU,
Ihe ndi ozo.

Omume ọgwụ

Farmasulin bu ogwu nke nwere akpomkpom hypoglycemic. Farmasulin nwere insulin, ihe na-edozi metabolism. Na mgbakwunye na ịhazi metabolism nke glucose, insulin na-emetụtakwa ọtụtụ usoro anabolic na mgbochi catabolic na anụ ahụ. Insulin na - akwalite njikọ nke glycogen, glycerin, protein na ọdụdụ na anụ ahụ, ma na - emekwa ka mmụba nke amino acid belata ma glycogenolysis, ketogenesis, neoglucogenesis, lipolysis na catabolism nke protein na amino acid.
Farmasulin N bụ ọgwụ nwere ọgwụ ngwa-ngwa. Nwere insulin mmadụ nwetara site na teknụzụ DNA ọzọ. A na-ahụta ọgwụgwọ ahụ ka nkeji iri atọ na atọ gachara nchịkwa subcutaneous ma were awa 5-7. A na-etinye uche ịta mmiri plasma kachasị elu n'ime awa 1-3 mgbe a gbasịrị ya.

Mgbe ị na-eji ọgwụ Farmasulin H NP eme ihe, a na-ahụ oke pilas plasma nke ihe na-arụ ọrụ mgbe awa 2-8 gachara. Mmetụta ọgwụgwọ na-amalite n'ime nkeji 60 mgbe nchịkwa gachara wee dịgide ruo awa 18 ruo 24.
Mgbe ị na-eji ọgwụ Farmasulin N 30/70, ọgwụgwọ ọgwụgwọ na-etolite n'ime oge 30-60 wee dịgide ruo awa 14-15, na ụfọdụ ndị ọrịa ruo awa 24. A na-ahụta oghere plasma kachasị elu na - arụ ọrụ n'ime ọrụ awa iri na asatọ awa iri asatọ na asatọ gachara.

Ofzọ nke ngwa

Farmasulin N:
Ezubere ọgwụ a maka nchịkwa subcutaneous na intravenous. Na mgbakwunye, enwere ike ịhazi otu esi ahụ intramuscularly, ọ bụ ezie na subcutaneous na intravenous management ka dị mma. Ọgwụ dọkịta na usoro nhazi nke ọgwụ Farmasulin N bụ ndị dọkịta kpebisiri ike, na-eburu n'uche mkpa onye ọrịa ọ bụla. N’ime ihe ozo, a na-atụ aro ị drugụ ọgwụ a n’ubu, apata ụkwụ, ma ọ bụ n’akụkụ afọ. N'otu ebe, a na-atụ aro ịgba ọgwụ ka ọ dịkarịa ala oge 1 kwa ọnwa. Mgbe ị na-abanye, zere itinye ihe ọ bụla na oghere akwara. Etekwala ebe a na-agba ntụtụ.

A ga-eji pensụl ntụtụ dị na katrized ndị ahụ ka ejiri mkpịsị sirinji nke akpọrọ “OA”. A na-ahapụ ya ka ọ jiri naanị ihe doro anya na-enweghị ụcha na enweghị ihe a na-ahụ anya. Ọ bụrụ na ọ dị mkpa ịhazi ọtụtụ nhazi insulin, a ga-eme nke a site na iji pensụ dị iche iche. Banyere usoro iji chaja cha cha, dịka iwu, a na-enye ozi na ntuziaka maka mkpịsị sirinji.

Site na ntinye nke osisa ya na vials, ekwesịrị iji sirinji, ngụsị akwụkwọ nke dabara na ụdị insulin a. A na-atụ aro ka etinyere sirinji otu ụlọ ọrụ na ụdị iji dozie ọgwụ Pharmasulin N, ebe ọ bụ na iji sirinji ndị ọzọ nwere ike iduga dosing adịghị mma. Naanị nkenke doro anya na-enweghị ụcha nke na-enweghị ihe a na-ahụ anya ka akwadoro. Ekwesịrị iji ọgwụ ntụtụ dị n'okpuru ọnọdụ. A na-atụ aro ihe ngwọta nke okpomoku ime ụlọ. Iji sere ihe nkedo n'ime sirinji ahụ, ị ga-ebu ụzọ dọba ikuku n'ime sirinji na akara kwekọrọ na insulin chọrọ, tinye agịga ahụ na ikuku na ikuku. Mgbe nke ahụ gasị, a na-agbanye karama ahụ elu ma nakọta ego achọrọ. Ọ bụrụ na ọ dị mkpa, iwebata insulins dị iche iche maka nke ọ bụla na-eji sirinji na agịga iche.

Farmasulin H NP na Farmasulin H 30/70:
Farmasulin N 30/70 - ngwakọta edozi edozi edozi Farmasulin N na Farmasulin H NP, nke na-enye gị ohere ịbanye insulins dị iche iche n'emeghị nkwadebe insulin.

A na-achịkwa Farmasulin H NP na Farmasulin H 30/70 n'okpuru subcutaneously na-agbaso usoro ase. A na-etinye ọgwụ ntụtụ n'okpuru ubu, ihe mkpuchi, apata ụkwụ ma ọ bụ afọ, agwara iburu n'uche na n'otu saịtị ahụ ka ekwesịghị ime ihe karịrị oge 1 kwa ọnwa. Zere kọntaktị na ngwọta ahụ n'oge ntụtụ. Ọ ga-enye ohere iji naanị ihe eji eme ihe mgbe agbanyeghị mgbe a na-enweghị flakes ma ọ bụ sedimenti dị na mgbidi nke vial ahụ. Tupu ị mee ihe, tụọ karama ahụ n'ọbụ aka gị ruo mgbe ị ga -achite ihe na-enye ihe ọ bụla. Amachibidoro ịmegharị karama ahụ, ebe nke a nwere ike iduga n'ichepụta ụfụfụ na ihe isi ike na ịha oke oke. Jiri sirinji nke nwere ihe omumu dabara na insulin. Oge dị n'etiti nchịkwa ọgwụ na nri iri kwesịrị ịkarị ihe 45-60 nkeji maka ọgwụ Farmasulin H NP ma ọ gafee nkeji iri atọ maka ọgwụ Farmasulin H 30/70.

N'oge ị Farụ ọgwụ Farmasulin, a ga-agbaso ihe oriri.
Iji chọpụta nha ahụ, ekwesịrị ịbanye larịị nke glycemia na glucosuria n'oge ụbọchị na ọkwa nke glycemia na-ebu ọnụ.
Iji tọọ nkwusioru na sirinji ahụ, ị ga-ebu ụzọ dọba ikuku n'ime sirinji na akara nke na-ekpebi ọgwụ achọrọ, tinyezie agịga ahụ na vial ma na-agba ọbara. Na-esote, kpoo karama ahụ ma kpakọta ego achọrọ maka nkwụsị.

Ekwesịrị inye ọgwụ ọgwụ site na ijide anụ ahụ n’ogiri n’etiti mkpịsị aka ya ma tinye agịga n’akụkụ ogo 45. Iji gbochie nrugharị nke insulin mgbe nchịkwa nke nkwusioru ahụ, ekwesịrị ịpịa ebe ntụtụ ahụ. Amachibidoro ya ịsacha ebe a na-agbanye insulin.
Mmegharị ọ bụla, gụnyere ụdị mwepụta, ika na ụdị insulin, chọrọ nlekọta nke dọkịta.

Nsonaazụ

N'oge usoro ọgwụgwọ nke Pharmasulin, mmetụta kachasị emetụta bụ hypoglycemia, nke nwere ike ibute enweghị mmụọ na ọnwụ. Ọtụtụ mgbe, hypoglycemia bụ nsonaazụ nke ịwụ nri, na-a insụ nnukwu insulin ma ọ bụ nrụgide gabigara ókè, yana ị alcoholụ mmanya. Iji zere mmepe nke hypoglycemia, a ga-agbaso usoro nri a na-atụ aro ya ma a ga-enye ọgwụ ahụ ike na ntinye dịka dọkịta si kwuo.

Na mgbakwunye, iji ọgwụ ọgwụ Farmasulin ruo ogologo oge, mmepe nke insulin na-eguzogide na atrophy ma ọ bụ hypertrophy nke okpukpo subcutaneous fatịlaịza na saịtị ịgba ntụtụ ga-ekwe omume. Ọ ga-ekwe omume mmepe nke mmeghachi omume hypersensitivity, gụnyere ndị nwere usoro nke hypotension artpot, bronchospasm, oke ị ,ụ iyi na urticaria.
Na mmepe nke mmetụta ndị ị na-achọghị, ị kwesịrị ịkpọtụrụ dọkịta, ebe ụfọdụ n'ime ha nwere ike ịchọ ịkwụsị ọgwụ na ọgwụgwọ pụrụ iche.

Ihe ngbanwe

Edebere Farmasulin maka ndị ọrịa nwere amamịghe nke akụkụ ahụ ọgwụ ahụ.
Amachibidoro Farmasulin maka iji hypoglycemia.
Ndị ọrịa nwere ọrịa shuga ogologo oge, neuropathy na-arịa ọrịa shuga, yana ndị ọrịa na-anata beta-igbochi, kwesịrị iji ọgwụ ọgwụ ahụ jiri nlezianya mee ihe, ebe ọ bụ na n'ọnọdụ ndị dị otú ahụ, ọrịa hypoglycemia nwere ike ịdị nro ma ọ bụ gbanwee.

Ga-agakwuru dọkịta gị banyere etu ị theụ ọgwụ ike si mee ka ọ bụrụ nke mmepe nke adrenal, akụrụ, pituitary na thyroid gland dysfunctions, yana n'ụdị ọrịa dị ukwuu, dịka na nke a, enwere ike ịchọ mgbanwe insulin dose.
N'ime omume ụmụaka, maka ihe ahụike, a na-ahapụ ya ka ọ jiri ọgwụ ọgwụ Pharmasulin malite mgbe a mụrụ ya.
Ekwesịrị ịkpachara anya mgbe ị na - akwọ ụgbọ mmiri nwere ike ị nweghị nchekwa yana ịkwọ ụgbọ ala n'oge ọgwụgwọ ọgwụ ọgwụ.

Ime

Enwere ike iji Farmasulin mee ụmụ nwanyị dị ime, na agbanyeghị, ekwesịrị iburu n'uche na n'oge afọ ime, a ga-elebara nlebara anya nke nhọrọ insulin anya, n'ihi na n'oge a, mkpa insulin nwere ike ịdị iche. A na-atụ aro ka ị gaa hụ dọkịta gị ma ọ bụrụ na ị dị ime ma ọ bụ na-eme atụmatụ ịtụrụ ime. Ekwesiri iji nlezianya nyochaa glucose plasma n'oge ịtụrụ ime.

Mkparịta ụka ọgwụ ọjọọ

Enwere ike belata ịdị mma nke ọgwụ Farmasulin mgbe ejikọtara ya na ọgwụ mgbochi ọgwụ, ọgwụ thyroid, glucocorticosteroids, beta2-adrenergic agonists, heparin, nkwadebe lithium, diuretics, hydantoin, na ọgwụ antiepileptik.

Enwere mbelata na insulin chọrọ ya na iji ọgwụ ndị a na-akpọ ọgwụ ọgwụ ọgwụ ọnụ, ọgwụ salicylates, monoamine oxidase inhibitors, ihe ndị na-agbanwe agbanwe, ndị na-anabata ihe, ndị na-eme ihe ọ alcoholụ alcoholụ na phenylbutazone.

Mmekọrịta na ọgwụ ndị ọzọ na ụdị mmekọrịta ndị ọzọ

Drugsfọdụ ọgwụ na-emetụta metabolism. Ekwesịrị ịgwa dọkịta ahụ maka ọgwụgwọ ọgwụ ọ bụla enyere na njikọta insulin mmadụ.

Ọ bụrụ n’ịchọrọ iji ọgwụ ndị ọzọ, ị ga-agakwuru dọkịta gị.

Mkpa insulin nwere ike ịbawanye elu n'iji ọgwụ eji arụ ọrụ hyperglycemic, dịka ọgwụ mgbochi, glucocorticoids, homonụ thyroid na homonụ na-eto, danazole, β ₂ ọrịa mmụọ (dịka ọmụmaatụ ritodrin, salbutamol, terbutaline), thiazides.

Mkpa insulin nwere ike ibelata site na iji ọgwụ ọjọọ eme ihe na hypoglycemic ọgwụ, dị ka ọgwụ hypoglycemic ọgwụ, salicylates (dịka ọmụmaatụ acetylsalicylic acid), sulfaantibiotics, ụfọdụ antidepressants (MAO inhibitors), ụfọdụ angiotensin-inhibiting enzyme inhibitors (blockptenaprilprorillligligliglig, Captapri) β-blockers na-adịghị ahọpụta ma ọ bụ mmanya na- egbu egbu.

Somatostatin analogues (octreotide, lanreotide) nwere ike ịkwalite ma mee ka ikelata insulin.

Njirimara ngwa

Ekwesịrị ịgbanwe ụdị ma ọ bụ ụdị insulin ọ bụla n'okpuru nlekọta ahụike siri ike. Mgbanwe na itinye uche, akara (onye na-emepụta), ụdị (ngwa ngwa, ọkara, ogologo oge), ụdị (insulin anụmanụ, insulin mmadụ, analog nke insulin mmadụ) na / ma ọ bụ usoro nkwadebe (insulin nwetara site na iji teknụzụ DNA recombinant, banye n’adịghị ka insulin anụmanụ) nwere ike ịchọ mgbanwe onunu ogwu.

Usoro ịgwọ ọrịa ndị e nyere insulin na-arịa mmadụ nwere ike ịdị iche na usoro eji eme ọgwụgwọ insulin nke anụmanụ si malite. Ọ bụrụ na ọ dị mkpa maka ịmegharị dose, enwere ike ịme ụdị mgbanwe ahụ site na usoro izizi ma ọ bụ n'ime izu ole na ole ma ọ bụ ọnwa ole na ole.

N'ime ụfọdụ ndị ọrịa nwere ụdị mmeghachi omume hypoglycemic mgbe ha nyefere ha site na njikwa nke insulin nke anụmanụ sitere na nchịkwa insulin nke mmadụ, ekwesighi ịkọwapụta mmalite nke hypoglycemia ma ọ bụ dị iche na mgbaàmà ndị a na-ahụ na mbụ na ndị ọrịa a mgbe a na-emeso insulin anụmanụ. N'ime ndị ọrịa nwere mmụba dị ukwuu na ọkwa glucose ọbara (dịka ọmụmaatụ, n'ihi ike ọgwụgwọ insulin), ụfọdụ ma ọ bụ nke ọ bụla nke mgbaàmà ịdọ aka ná ntị mbụ banyere hypoglycemia nwere ike ịhụghị n'ọdịnihu, na ekwesịrị ịgwa ha. Ihe mgbaàmà mbụ nke hypoglycemia nwekwara ike ịdị iche ma ọ bụ na-enweghị ike ịkọwapụta na ndị ọrịa nwere ụdị ọrịa shuga na neuropathy mamịrị, ma ọ bụ na ndị ọrịa na-a ,ụ ọgwụ ndị ọzọ, dị ka β-blockers, na usoro ọgwụgwọ ejiri.

Hypoglycemia ma ọ bụ mmeghachi omume hyperglycemic nke na-emezighị emezi nwere ike ibute ọnwụ nke mmụọ, ma ọ bụ ọnwụ.

Ọgwụ ma ọ bụ kwụsịtụ nke ọgwụgwọ (karịsịa maka ndị ọrịa nwere ọrịa shuga na-akpata insulin) nwere ike ibute hyperglycemia na ketoacidosis nwere ike ịkpata ọrịa mamịrị.

Enwere ike ịme ọgwụ mgbochi na ọgwụgwọ insulin nke mmadụ, n'agbanyeghị na enwere obere nyocha karịa ka insulin anụmanụ si mee ka ọ dị ọcha.

Mkpa insulin na-agbanwe nke ukwuu site na ọrụ na -eme arụ ọrụ, glandia gland, akwara thyroid, akụrụ ma ọ bụ imeju.

Mkpa insulin nwekwara ike ịbawanye n’oge ọrịa ma ọ bụ n’okpuru mmetụta nke nrụgide mmetụta uche.

Mkpa maka ịhazigharị dose nwere ike ibilite ma ọ bụrụ na enwere mgbanwe na oke mmega ahụ ma ọ bụ nri ị na-eri.

Jikọtara ọnụ na pioglitazone

A kọwo ọrịa nke nkụda obi na ojiji nke pioglitazone na insulin, ọkachasị ndị ọrịa nwere ihe ndị dị ize ndụ maka ọdịda obi.

Jiri n’oge ime ma ọ bụ n’ịra.

Machekwa oke glucose ọbara n’ime ụmụ nwanyị dị ime dị nnukwu mkpa ma ọ bụrụ na eji insulin agwọ ya (n’ụdị shuga ndị metụtara shuga). Mkpa insulin na-ebelata mgbe ọnwa atọ dị n’afọ nke mbụ, emesịa ọ na-abawanye n’oge ọkara nke abụọ na nke atọ. Womenmụ nwanyị ndị nwere ọrịa shuga kwesịrị ịgwa ndị dọkịta banyere ime ha ma ọ bụ ebum n’uche ha ime.

Inwe nlebara anya na onyocha glucose ọbara na ahu ike dicha oke mkpa nye ndi nwanyi di ime nke nwere oria shuga.

N’ime ụmụ nwanyị nwere ọrịa shuga, n’oge a na-enye nwa ara, enwere ike ịhazi nhazi insulin na / ma ọ bụ nri.

Ikike iji metụta ọnụego mmeghachi omume mgbe ị na-anya ụgbọala ma ọ bụ usoro ndị ọzọ.

Hypoglycemia nwere ike imebi ihe nlebara anya na mmeghachi omume na-adịghị mma, ya bụ, ọ bụ ihe egwu dị na ọnọdụ n'ọnọdụ chọrọ àgwà ndị a kpọtụrụ aha, dịka ọmụmaatụ, mgbe ị na-anya ụgbọ ala ma ọ bụ na-arụ ọrụ igwe.

Ekwesịrị ịgwa ndị ọrịa banyere ihe ị ga-akpachara anya tupu ha akwọ ụgbọala iji zere ọnọdụ hypoglycemia, ọkachasị ma ọ bụrụ na mgbaàmà mbido hypoglycemia na-anọghị ma ọ bụ na-akọwaghị ya, ma ọ bụ ma ọ bụrụ na ọnọdụ ịba ụba hypoglycemia na-apụta ugboro ugboro. N'ụdị ndị ahụ, akwọla ụgbọala.

Mmeghachi omume ọjọọ

Hypoglycemia bụ mmetụta ndị mmadụ na-enwekarị na ọgwụ insulin na ndị ọrịa na-arịa ọrịa shuga. Nnukwu hypoglycemia nwere ike ibute enweghị mmụọ, n'ọnọdụ ụfọdụ oke - ọnwụ. A naghị enye data gbasara ugboro ole hypoglycemia, ebe ọ bụ na hypoglycemia nwere njikọ nke insulin yana ihe ndị ọzọ, dị ka nri onye ọrịa na ọkwa nke mmega ahụ.

Enwere ike igosipụta ihe ngosipụta nke ihe nfụkasị mpaghara site na ngbanwe saịtị ahụ, nchapu nke anụ ahụ, ọzịza, itching. Ha na-abụkarị site ụbọchị ole na ole ruo ọtụtụ izu. N'ọnọdụ ụfọdụ, ejikọghị ya na insulin, mana ya na ihe ndị ọzọ, dịka ọmụmaatụ, mgbakasị ahụ mejupụtara ndị na-asacha akpụkpọ ma ọ bụ enweghị ahụmịhe na injers.

Sisikasị mmiri bụ ihe mmetụta dị njọ ma nwee ụdị nfụkasị nke insulin, gụnyere ihe nfụkasị ahụ dum, ahụ erughị ala, iku ume, mbelata ọbara mgbali elu, ụba obi, yana ọsụsọ. Ọnọdụ ndị na-emetụta oke ọrịa bụ ihe na-egbu ndụ. N'ọnọdụ ụfọdụ nke oke nfụkasị ahụ na Farmasulin ® N NP, ekwesịrị ịme ihe kwesịrị ekwesị ozugbo. Ọ nwere ike ịdị mkpa iji dochie anya ọgwụ insulin ma ọ bụ ịtụgharị uche.

N’oge na-adịghị anya, lipodystrophy nwere ike ime n’ebe a na-agba ya.

A kọrọ na edema maka iji ọgwụ insulin mee ihe, na ọnọdụ ndị nwere mbelata metabolism na mbụ, ọ ka mma site na ọgwụ insulin kpụ ọkụ n'ọnụ.

Ngwakọta na ụdị ntọhapụ

FARMASULIN® H NP

kwụsịtụ. d / n’ime. 100 IU / ml fl. 10 ml, Nke 1
kwụsịtụ. d / n’ime. 100 Carter IU / ml 3 ml, Nke 5

Human insulin 100 IU / ml
Ihe ndi ozo: m-cresol m-cresol, glycerol, phenol, sulfate protamine, zinc oxide, sodium phosphate dibasic, hydrochloric acid 10% ma obu mmiri sodium hydroxide 10% (rue pH 6.9-7.5), mmiri nke ogwu ogbugba.
1 ml nke Farmasulin N NP nwere 100 IU nke insulin biosynthetic mmadụ mere site na iji teknụzụ recombinant DNA.

FARMASULIN® H 30/70

kwụsịtụ. d / n’ime. 100 IU / ml fl. 10 ml, Nke 1
kwụsịtụ. d / n’ime. 100 Carter IU / ml 3 ml, Nke 5

Human insulin 100 IU / ml
Ihe ndi ozo: m-cresol m-cresol, glycerol, phenol, sulfate protamine, zinc oxide, sodium phosphate dibasic, hydrochloric acid 10% ma obu mmiri sodium hydroxide 10% (rue pH 6.9-7.5), mmiri nke ogwu ogbugba.
1 ml nke Farmasulin H 30/70 nwere 100 IU nke insulin biosynthetic mmadụ mere site na iji teknụzụ recombinant DNA.

Mlọ ọgwụ

Farmasulin N - insulin na-eme ihe ngwa ngwa, bụ nkwadebe nke insulin mmadụ na-enweta site na teknụzụ DNA ọgwụ ọzọ.
Pharmlọ ọgwụ ọgwụ nke insulin anaghị egosipụta ọrụ metabolism nke homonụ.
Mmalite nke mmetụta ahụ bụ nkeji iri atọ mgbe nchịkwa subcutaneous gasịrị. A na-ahụkarị ohere kachasị elu n'agbata 1 na awa 3 mgbe ịgba ọgwụ ịgba. Ogologo oge iji nọgide na-etinye uche gị na ọgwụgwọ sitere na 5 ruo 7 awa. Ọrụ insulin dịgasị iche iche dabere na nha ya, saịtị ịgba ntụtụ, ọnọdụ ikuku na ọrụ ahụike nke onye ọrịa.
N'oge ọmụmụ toxicological, enweghị ihe ọ bụla dị njọ metụtara ojiji nke iji ọgwụ ọjọọ ahụ.