AKTRAPID NM PENFILL (ACTRAPID HM PENFILL) ntuziaka maka ojiji
1dị shuga atọ nke ọrịa mellitus, ụdị shuga mellitus 2: ọkwa nke nguzogide ọgwụ ọgwụ hypoglycemic, nguzogide nke ọgwụ hypoglycemic ọgwụ (ọgwụgwọ njikọ),
ọrịa mamịrị ketoacidosis, ketoacidotic na hyperosmolar coma, ọrịa shuga mellitus nke mere n'oge ịtụrụ ime (ma ọ bụrụ na usoro ọgwụgwọ anaghị eri nri),
maka oge adịghị n'etiti ndị ọrịa na-arịa ọrịa shuga mellitus megide ọrịa na-efe efe, na-enwe ọrụ ịwa ahụ na-abịanụ, mmerụ ahụ, ịmụ nwa, nsogbu nke metabolic, tupu ịgbanwee ọgwụgwọ na usoro insulin ogologo oge.
Leasedị mwepụta, ihe mejupụtara na nkwakọ
Ngwọta nke nsị ahụ doro anya, enweghị agba.
| 1 ml | |
| insulin na-asọpụta (injinị mkpụrụ ndụ mmadụ) | 100 IU * |
Ndị e mere: zinc chloride, glycerol, metacresol, hydrochloric acid na / ma ọ bụ sodium hydroxide solution (iji lekọta pH), mmiri d / i.
* 1 IU dabara na 35 μg nke insulin na-eme mmadụ.
3 ml - katalọgụ iko (5) - ngwugwu nke kaadiboodu.
Omume ọgwụ
Actrapid ® NM bụ nkwadebe insulin na-eme nwa obere oge nke ihe omimi nke DNA sitere na njiri Saccharomyces. Mbelata ogo nke glucose n'ọbara na-apụta n'ihi mmụba nke ụgbọ njem akwara ọbara mgbe ọ jikọsịrị insulin na ndị na-anabata insulin na akwara na adipose yana mbelata nke imeju na -emepụta glucose. Normalization nke plasma glu ịta (ruo 4.4-6.1 mmol / l) site na nlekọta nke Actrapid ® NM na ndị nlekọta ahụike siri ike bụ ndị mere ịwa ahụ siri ike (ndị ọrịa 204 na-arịa ọrịa shuga mellitus na ndị ọrịa 1344 na-arịa ọrịa shuga mellitus) onye nwere hyperglycemia (plasma glucose concentrated> 10 mmol / L), belatara ọnwụ site na 42% (4.6% kama 8%).
Omume nke ọgwụ Actrapid ® NM na-amalite n'ime ọkara otu awa mgbe nchịkwa gasịrị, mmetụta kachasị na-apụta n'ime awa 1.5-3.5, ebe ngụkọta oge nke ihe ahụ bụ ihe dịka awa 7-8.
Data Nchekwa nke ime
Na omumu ihe omumu, tinyere akwukwo banyere ogwu ihe banyere ogwu, ihe omumu nke otutu, otutu ihe omumu nke ihe omumu, ihe banyere oria, ma oghaghi ihe ojoo nye ndi mmadu.
Mlọ ọgwụ
T 1/2 nke insulin si n’ọbara bụ naanị nkeji ole na ole.
Ogologo oge nke ihe insulin na-eme bụ n'ihi nzere, nke dabere na ọtụtụ ihe (dịka ọmụmaatụ, na insulin insulin, usoro na ebe nlekọta, ọkpụrụkpụ nke subcutaneous abụba oyi akwa na ụdị ọrịa shuga mellitus). Yabụ, usoro ọgwụ insulin na nke insulin na-enwe mgbanwe dị mkpa na ya.
A na - enweta C max nke insulin na plasma n'ime awa 1.5-2.5 mgbe nchịkwa sc gasịrị.
O nweghị ihe akpọrọ ihe na-egbochi protein amasara ahụ, ewezuga ọgwụ mgbochi insulin (ọ bụrụ na ọ dị).
A na-ewepụ insulinase mmadụ ma ọ bụ enzymes na-eme ka insulin na-ehichapụ ya, ikekwe site na protein disulfide isomerase.
Echere na na molekul nke insulin mmadu nwere otutu saịtị nke cleavage (hydrolysis), agbanyeghị, ọ nweghị nke metabolites guzobere n'ihi nsachapụ adịghị arụ ọrụ.
A na-ekpebi T 1/2 site na nha etu esi enweta ya site na anụ ahụ dị n'okpuru ala. Yabụ, T 1/2 yikarịrị ka ị ga - enwe mmịfe, kama ịbụ ezigbo iwepu insulin na plasma (T 1/2 nke insulin site n'ọbara ọbara bụ naanị nkeji ole na ole). Mmụta emere gosiri na T 1/2 bụ ihe dịka awa 2-5.
Childrenmụaka na ndị nọ n'afọ iri na ụma
A mụrụ profaịlụ pharmacokinetic nke ọgwụ Actrapid ® NM n’obere ụmụaka nwere ọrịa shuga (mmadụ 18) nọ n’agbata afọ 6-12 na afọ iri na ụma (n’agbata afọ 13-17). Agbanyeghi na data ndi enwetara bu ihe oke, ha gosiputara na profaịlụ ogwu nke Actrapid ® NM n’ebe umuaka na umuaka di. N'otu oge ahụ, ekpughere ọdịiche dị n’etiti afọ dị iche iche site na ngosipụta dị ka C max, nke na-ekwusi ike ọzọ mkpa nke ịhọrọ otu.
Usoro usoro onunu ogwu
Emere ọgwụ a maka SC na / okwu mmeghe.
A na-ahọrọ ọ̀gwụ nke ọgwụ n’otu n’otu, na-eburu n'uche mkpa ndị ọrịa.
Dị ka ọ dị, chọrọ insulin na-esite na 0.3 ruo 1 IU / kg / ụbọchị. Needchọrọ insulin kwa ụbọchị nwere ike ịdị elu karịa na ndị ọrịa nwere nguzogide insulin (dịka ọmụmaatụ, n'oge oge uto, yana na ndị ọrịa na-ebu oke ibu), na-agbadata na ndị ọrịa nwere ọgwụ insulin na-apụtakarị ihe.
A na-enye ọgwụ ahụ nkeji iri atọ tupu nri ma ọ bụ nri nwere carbohydrates. Actrapid ® NM bụ insulin na-adị mkpụmkpụ ma enwere ike iji ya na insulins dị ogologo.
A na-ejikarị emechi emereme sub NM ka ana-edobe subcutaneously na mpaghara nke mgbidi ihu. Ọ bụrụ na nke a dabara adaba, mgbe ahụ injections nwekwara ike ịme n'apata ụkwụ, mpaghara gluteal ma ọ bụ n'olu nwere ike ịmị n'ubu. Site na ntinye ogwu banyere mpaghara nke ogiri n’afọ, a na-enweta ihe ngwa ngwa karịa iwebata n’ime mpaghara ndị ọzọ. Ọ bụrụ ntụtụ ka ejiri n'oghere gbatịa anụ ahụ, belata ọghọm nchịkwa intramuscular nke ọgwụ ahụ na-ebelata. Mkpịsị ahụ kwesịrị ịdị n’okpuru anụ ahụ ma ọ dịkarịa ala 6 sekọnd, nke na-ekwe nkwa ị aụ ọgwụ zuru oke. Okwesiri igbanwe ebe igba ogwu n’etiti mpaghara anatomical iji belata nsogbu nke lipodystrophy. Actrapid ® NM nwekwara ike ịbanye / nbanye yana usoro ndị ọkachamara ahụ nwere ike ịme ya.
Na / na ntinye nke ọgwụ Actrapid ® NM Penfill ® sitere na katriki, a na-ahapụ naanị dịka ihe dị iche na enweghị karama. N'okwu a, ị ga-ewere ọgwụ ahụ banye sirinji insulin na-enweghị ikuku ikuku ma ọ bụ nye ya site na iji usoro infusion. Usoro a kwesịrị ịbụ naanị dọkịta.
Emebere Actrapid ® NM Penfill ® maka iji insulin inspekt Novo Nordisk yana agịga NovoFine ® ma ọ bụ NovoTvist ®. Ekwesịrị ịchọpụta nkọwa zuru ezu maka ojiji na nchịkwa nke ọgwụ ahụ.
Ọrịa concoitant, nke na-efe efe ma na-efe efe, na -emekarị ahụ insulin nwere ahụ. Ọ ga-adị mkpa ịgbanwe nguhie ma ọ bụrụ na onye ọrịa ahụ nwere ọrịa ndị akụrụ, akụrụ, ọrụ akwara, pituitary ma ọ bụ thyroid gland.
Mkpa maka ịhazigharị dose nwekwara ike ibilite mgbe ị na-agbanwe mmega ahụ ma ọ bụ nri onye ọrịa na-eri. Imezi dose mgbe ị na-ebufe onye ọrịa n’otu ụdị insulin na nke ọzọ.
Nsonaazụ
Ihe omume kachasị njọ na insulin bụ hypoglycemia. N'oge ọnwụnwa nke ụlọ ọgwụ, yana n'oge iji ọgwụ ahụ mgbe a tọhapụsịrị ya na ahịa ndị ahịa, a chọpụtara na ọnọdụ nke hypoglycemia dịgasị iche dabere na ọnụ ọgụgụ ndị ọrịa, usoro ị ofụ ọgwụ ahụ, yana ọkwa nke njikwa glycemic.
Na nmalite ọmụmụ ọgwụ insulin, njehie na-egbu mmụọ, edema na mmeghachi omume nwere ike ime na ntụtụ ahụ (gụnyere mgbu, redness, hives, mbufụt, ọnya ahụ, ọzịza na itching na saịtị ịgba ntụtụ). Mgbaàmà ndị a anaghị adịte aka. Ọganiihu ngwa ngwa na njikwa glycemic nwere ike iduga 'ọnọdụ nro ọria mgbu,' nke na-agbanwegharị. Enstụgharị uche na ọgwụ insulin na mmụba dị mma n'ịchịkwa metabolism metabolism nwere ike ibute ịbelata nwa oge na ọnọdụ nke ọrịa mamịrị, ebe nkwalite ogologo oge na njikwa glycemic na-ebelata ohere nke inwe ọrịa mamị retinopathy.
Nsonaazụ niile ndị a gosipụtara n’okpuru, dabere na data sitere na nnwale ụlọ ọgwụ, a na-ekekọta ọnụ ọgụgụ oge nke mmepe dịka usoro MedDRA na usoro ahụ. A na-akọwapụta mmetụta nke nsonaazụ ndị ọzọ dịka:
- ọtụtụ mgbe (≥ 1/10),
- mgbe (≥ 1/100 ka nsogbu ọgba aghara nke immune System):
- ugboro ugboro - urticaria, ọnya ọnya,
- ọ na-esikarị ike - mmeghachi omume anaphylactic.
Ọrịa metabolism na nri nri:
- ọtụtụ mgbe - hypoglycemia.
Mmebi nke usoro ụjọ ahụ:
- ugboro ugboro - ọrịa neuropathy na-adịghị ala ala ("nnukwu ihe mgbu neuropathy").
Mmebi nke akwara nke ọhụụ:
- ugboro ugboro - refractive njehie,
- o siri ike - ọrịa ịrịa ọrịa retinopathy.
Ọkpụkpụ sitere na anụ ahụ yana anụ ahụ dị n'okpuru ala:
- ugboro ugboro - lipodystrophy.
Ọrịa na nkwarụ izugbe na saịtị ịgba ahụ:
- ugboro ugboro - mmeghachi omume na saịtị ịgba ahụ,
- ugboro ugboro - edema.
Nkọwapụta mmeghachi omume ọjọọ nke onwe onye:
A chọpụtara mmeghachi omume a na-ahụkarị nke oke ọbara (gụnyere oke ahụ ọkụ, itching, sweating, gastrointestinal disturbances, angioedema, neefshị ike, palpitations obi, belata ọbara mgbali, na nkụda / ọnwụ nke nsụhọ, nke nwere ike igbu ndụ).
Hypoglycemia bụ mmetụta kachasị emetụta. Ọ nwere ike ịmalite ma ọ bụrụ na insulin n ’oke dị na elele insulin chọrọ. Nnukwu ọbara ọgbụgba nwere ike ibute mwepu na / ma ọ bụ ịmị mkpụrụ, ụbụrụ nwa oge, ma ọ bụ ọnwụ agaghị arụ ọrụ, ma ọ bụdị ọnwụ. Ihe mgbaàmà hypoglycemia, dịka iwu, na-etolite na mberede. Ndị a nwere ike ịgụnye “ọsụsọ oyi”, pallor nke anụ ahụ, ike ọgwụgwụ, ụjọ ahụ ma ọ bụ ịma jijiji, nchekasị, ike ọgwụgwụ pụrụ iche, ma ọ bụ adịghị ike, nchepụta, mbelata, ụra, agụụ dị njọ, ọhụụ na-acha ọkụ, isi ọwụwa, ọgbụgbọ, na ngwa ngwa. nkuchi obi.
Achọpụtala nsogbu na-adịghị ala ala nke lipodystrophy. Lipodystrophy nwere ike ịmalite na ebe injection.
Ime na lactation
Enweghị mgbochi ọ bụla na ojiji nke insulin n'oge ime, ebe insulin anaghị agafe ihe mgbochi placental.
Ma ọrịa hypoglycemia na hyperglycemia, nke nwere ike ịmalite n'ọnọdụ nke usoro ọgwụgwọ ahọpụtaghị nke ọma, na-eme ka ihe ọghọm ndị dị na nwa ebu n'afọ na ọnwụ nke nwa ebu n'afọ. Shouldmụ nwanyị dị ime nwere ọrịa shuga kwesịrị ileba anya n’oge ha dị ime, ha kwesịrị inwe nkwalite nke ọkwa glucose ọbara, otu ndụmọdụ a na-emetụta ụmụ nwanyị na-eme atụmatụ ime.
Mkpa insulin na-agbadata n'oge ọnwa atọ nke mbụ nke afọ ime wee jiri nwayọ na nke abụọ na nke atọ.
Mgbe ịmụchara nwa, mkpa insulin dị, dịka iwu, na-alaghachi ọsọ ọsọ na ọkwa a hụrụ tupu ime ime.
Enweghịkwa mmachi iji ọgwụ Actrapid ® NM na-azụ ara. Ingmụrụ nne na-enye nwa ara adịghị ize ndụ nye nwa ahụ. Agbanyeghị, nne nwere ike imezi usoro onunu ogwu nke Actrapid ® NM na / ma ọ bụ nri.
Ngwongwo ogwu
Ngwakọta ọrụ na-arụ ọrụ na ọgwụ Actrapid Hm Penfill bụ insulin na-arụ ọrụ mmadụ. A na - enweta ihe a site na usoro deoxyribonucleic acid. Isi ọrụ ọgwụ a, dị ka nkwadebe insulin ọ bụla, bụ nhazi. Site na ya, a na-eme mbelata nke glucose ọbara, yana mmụba nke nnweta glucose site na anụ ahụ nke anụ ahụ na ime ka imeju na - egbochi mkpụkọ glucose site na umeji. Na mgbakwunye, usoro mmebi nke abụba na abụba na protein nke protein. Emebewo ya site na ogwu na-agbadata ọkwa nke glucose n'ọbara mgbe onye ọrịa ahụ jirila Actrapid amalite n'ime nkeji iri atọ mbụ. Ọgwụ a na-enweta arụmọrụ ya kachasị na oge site na otu awa ruo atọ. Ogologo oge nke ime ihe, dịka iwu, anaghị agafe awa asatọ. Ekwesịrị iburu n'uche na njiri mara nwa oge nwere ike ịdị iche dabere na njirimara onye ọrịa ahụ.
Ngwakọta na ụdị ntọhapụ
A na - eji mmiri ọgwụ ndị a emepụta ọgwụ: • ihe na - arụ ọrụ n'ụdị insulin nke mmadụ nwere mmiri, • ihe ndị ọzọ, gụnyere zinc chloride, glycerin zinc, metacresol, hydrochloric acid, sodium oxidanide, mmiri dị ọcha maka ịgba ọgwụ. Ntọhapụ nke ọgwụ dị n'ụdị edozi maka nchịkwa subcutaneous na intravenous. Ihe ngwọta bụ ngwakọta agwakọta, nke na-enweghị ụcha. Ihe kachasị dị na nkwakọ ngwaahịa bụ karama iko. Ana etinye vials na ngwugwu ọnya na-acha na ọnụọgụ atọ. Mpempe ogbe na-acha uhie ise, yana ntuziaka maka ojiji, na-etinye n'ime igbe kaadiboodu nke acha ọcha na-enweghị atụ.
Nsonaazụ
Mmeghachi omume ndị na-esote nwere ike ịme n'oge a na-eji ọgwụ ahụ: • ọsụsọ na-aba ụba, • ọnọdụ ụjọ, • ịma jijiji nke mkpịsị aka, • ike ọgwụgwụ, • ike gwụrụ, adịghị ike, • mgbadata uche na-agbada, • isi ọwụwa, nkụda mmụọ, • agụụ riri, • mmetụta nke ọgbụgbọ, • imebi ụda nke akwara obi, • ọnya ụkwụ, • mgbu nke ihu, • wedata ọbara mgbali elu, • ume dị mkpụmkpụ, • ọnya afọ, itching.
Ihe ngbanwe
Ekwesighi iji ọgwụ Aktrapid Hm ma ọ bụrụ na otu n'ime ihe ndị a na - esochi: hy na - enyocha akụkụ ụfọdụ nke ọgwụ ahụ, • ọbara shuga dị ala, • mmeghachi omume nfụkasị insulin, • akpụ nke puru na on-cell nke na - ebute n’usoro homonụ ma na - eduga iweda shuga dị ala.
Ime na lactation
Ozi dị ugbu a na-egosi na achọpụtaghị ọrịa nje ma ọ bụ mmetụta ọjọọ na nwa ebu n'afọ n’oge iji Actrapid. N'otu oge ahụ, a na-atụ aro nlezianya maka ndị ime ime na-arịa ọrịa shuga ma jiri ọgwụ a. Ekwuputala na ihe choro ka emeghe aru oru sitere na izu nke iri na ano nke ime ma jiri nwayọ too. Mgbe ịmụchara nwa, mkpa insulin na-ebelata, mana ka obere oge gasịrị, ọ laghachiri etu ọ dị n’oge gara aga. N'oge a na-enye nwa ara, a na-ahapụ iji ọgwụ eme ihe. Mgbe ụfọdụ, a na-achọ mgbanwe onunu ogwu dabere na nsonaazụ ya na onye ọrịa.
Ngwa: usoro na atụmatụ
A na-eji ọgwụ Actrapid Hm Penfill eme ihe subcutaneously na intravenously. Ọ bụ ọgwụ kacha mma ka dọkịta depụtara ya dabere na nyocha emere. N'ihi eziokwu ahụ bụ na ihe nke insulin na -akpata mkpụmkpụ dị mkpụmkpụ, otu n'ime ndụmọdụ ndị bụ isi mgbe ị na-eji ya bụ mkpa ijikọ ọgwụ a na insulins ogologo ma ọ bụ insulins na-ajụ.Ihe a chọrọ kwa ụbọchị maka insulin na-arịa mmiri, dịka iwu, si dị otu ụzọ n'ụzọ atọ ruo otu nkeji kwa kilogram nke ahụ dị ya. Mgbe ụfọdụ mkpa insulin karịrị akarịara ọnụ ọgụgụ dijitalụ egosipụtara na ndị ọrịa buru ibu ma ọ bụ n'oge ntorobịa. Iwebata ọgwụ a ga-ebufe ọkara elekere tupu nri. Ekwesịrị ịgha ọgwụ na Subcutaneous n'akụkụ nke ahụ n'ụzọ ahụ ewepu agịga ugboro ugboro n'otu ebe. A na-atụ aro ka akpachara anya na nchịkwa subcutaneous iji wezuga mmekpa ahụ ọghọm nke ihe ngwọta n'ime arịa ọbara. A na-enweta mmụba kachasị ngwa ngwa mgbe ejiri ya mee mpaghara mpaghara. Maka usoro nchịkwa onwe onye, onye ọrịa ahụ ga-agbaso ọtụtụ iwu dị mfe. Ndị a gụnyere ndị a: 1. Tupu iji Actrapid, ekwesiri inyocha nyocha nke ọma. O kwesịrị ịbụ otu ihe, yi na-enweghị ụcha. Ọ bụrụ na achọtara igwe ojii, ndò ma ọ bụ ihe ndị ọzọ na-emegide ya, amachibidoro iji ụdị ọgwụ a. 2. Tupu nchịkwa, a na-atụ aro ịsa aka gị nke ọma, yana ebe ọgbụgba ọkụ. 3. Mepee okpu nke sirinji tinye ntụtụ ọhụụ, na-agbanye ya ruo na njedebe. Ọ bụla agara insulin mmadụ ga-eji agịga ọhụrụ mee ya. 4. Ebe mwepụtapụ agịga site na akpati, jiri otu aka kwadebe ebe ntụtụ ahụ site na ịnakọta akpụkpọ ahụ n’obere atụrụ, ya na nke ọzọ, lelee sirinji nke ihe dị n’ime ka ọpụpụ. Gbaa mbọ hụ na enweghi vials na-abanye na vial ahụ. 5. Fanye agịga ahụ n'ime crease ma fanye ọdịnaya nke vial n'okpuru anụahụ. 6. Mgbe etinyere ya, wepụta agịga ahụ, na-ejide ebe ngbanye obere oge. 7. Wepụ agịga ahụ n'aka ma tụfuo ya. Ọ bụ naanị ndị ọkachamara ruru eru ka a ga-esi na-elekọta ya.
Mmekọrịta na ọgwụ ndị ọzọ
Enwere ọtụtụ ọgwụ na-emetụta ogo glucose na ahụ n’oge ha na-ejikọ Actrapid Hm. Yabụ, ọgwụ ndị nwere nnukwu mmetụta na monoamine oxidase na angiotensin na-agbanwe enzyme, yana ọgwụ dịka tetracycline, ethyl- (para-chlorophenoxy) -isobutyrate, dexfenfluramine, cyclophosphamidum, ndị na - ebuli usoro anabolic na ahụ, nwere ike ịkwalite ọrụ insulin mmadụ. Diuretics, sịntetik androgens, heparin, tricyclic antidepressants, glucocorticosteroids, psychotropic ọgwụ, iodinated derivatives nke tyrosine amino acid nwere ike na-enwe mmetụta na-egbochi ihe na insulin nke soluble. N'okpuru omume nke 3,4,5-trimethoxybenzoate methylreserpate na nyocha salicylic acid, mgbanwe nke ogo glucose n'ọbara ga-ekwe omume, ma na ntinye ma na-abawanye.
Dodoụbiga ya ókè
Ka ọ dị ugbu a, amataghị ị doseụ ọgwụ Actrapid, nke nwere ike ibute ịdoụbiga mmanya ókè. N'otu oge ahụ, mgbe ọ mere, mbelata ọbara shuga dị ka ụkpụrụ a siri ike kwere omume. N'okwu a, mgbaàmà ndị a na-egosi: • isi ọwụwa, • iwepụ uche n'ihe na oghere, • ike nke ike, enweghị ike, • Ọsụsọ na-aba ụba, • mgbanwe mgbanwe obi, • ịma jijiji nke mkpịsị aka, • imebiga ihe ókè, • ọgba aghara okwu. , • ndakpọ obi. Ọ bụrụ na mbelata shuga anaghị akpalite nnukwu nsogbu, yabụ onye ọrịa ahụ nwere ike iwepụ ya site na ị oụ glucose ọnụ. Maka ebumnuche ndị a, a na-atụ aro ka ndị nwere ọrịa shuga na-eri nri dị ụtọ ma ọ bụ ihe ọ drinksụ drinksụ mgbe niile. N'ihe banyere mgbe, n'ihi ịdalata shuga ọbara, onye ọrịa ahụ na-efukarị, a chọrọ nchịkwa ozugbo nke usoro dextrose intravenously, nke naanị ndị ọkachamara ruru eru ga-eme ya.
Ntụziaka pụrụ iche
Ekwesịrị ịbanye na ọgwụ insulin ọzọ n'okpuru nlekọta ahụike siri ike. Bụrụ na imebi usoro oriri a guzobere, yana mmụba n'ọrụ ọrụ kwa ụbọchị, a chọrọ ndozi usoro usoro ọgwụgwọ. Mmepe nke ọrịa nke akụrụ na umeji nwere ike belata mkpa maka insulin n'ihi mbelata nke usoro ihie ya. N'otu oge, ọrịa nke ọrịa na-efe efe nwere ike bụrụ ihe ndabere maka ịbawanye usoro ị drugụ ọgwụ. Usoro ị insụ ọgwụ insulin pụkwara ịnwe mgbanwe na nsogbu uche. Ekwesịrị iji ọgwụ ndị ọzọ mezuo site na ntinye kwesịrị ekwesị nke ọkachamara ọkachamara. Ebe ọ bụ na ịdalata na ịba ụba ọkwa shuga dị n'ọbara ga - ekwe omume n'oge ị na - a medicineụ ọgwụ, nke a nwere ike imetụta ịta ahụhụ n'ụzọ ọjọọ. N'oge dị otú ahụ, ị kwesịrị ịhapụ ịnya ụgbọ ala na ihe omume ndị ọzọ chọrọ nlebara anya.
Ọgwụ Aktrapid Hm Penfill nwere ngwaahịa analogous ndị a nwere ụdị ọrụ ọzọ: Apidra Solostar, Gensulin R, Biosulin R, Gansulin R, Insulin R bio R, Insuran R, Rosinsulin R, Insuman Rapid GT, Rinsulin R, Vosulin-Rsp, Novoraprap , Insuvit N, Insugen-R, Insular Asset, Farmasulin N, Humodar R, Himulin Regular.
Nyocha Ọgwụ
Ndị ọrịa na-a theụ ọgwụ Actrapid Hm, ruo oke ukwuu, mara na ụzọ dị mma arụmọrụ ya na ọsọ ya. Patientsfọdụ ndị ọrịa nwere mmetụta dị n'akụkụ oge nchịkwa ọgwụ subcutaneous, mana ọtụtụ mgbe nke a bụ nsonaazụ nke usoro ahọpụtara nke ọma.
Akwụkwọ ikike ahịa ọgwụ LO-77-02-010329 nke June 18, 2019
Etu esi eji: usoro onunu ogwu na usoro ọgwụgwọ
A na-ekpebi ọ̀gwụ na ụzọ nchịkwa nke ọgwụ a n’otu n’otu n’ebumnuche nke ọdịnaya glucose dị n’ọbara tupu nri na 1-2 awa mgbe nri, yana dabere na ogo glucosuria na njiri mara usoro ọrịa ahụ.
A na-elekọta ọgwụ ahụ s / c, na / m, na / n'ime, 15-30 nkeji tupu eri. Routezọ nchịkwa kachasị na-ahụkarị bụ sc. Na ketoacidosis na-arịa ọrịa shuga, coma mamịrị, n’oge usoro ịwa ahụ - in / in na / m.
Site na monotherapy, oge nchịkwa na-abụkarị ugboro 3 kwa ụbọchị (ọ bụrụ na ọ dị mkpa, ruo ugboro 5-6 kwa ụbọchị), a na-agbanwe saịtị injection oge ọ bụla iji zere mmepe nke lipodystrophy (atrophy ma ọ bụ hypertrophy nke subcutaneous fat).
Nkezi ubochi ubochi bu 30-40 PIECES, na umuaka - 8 PIECES, mgbe ahu na otu ubochi ubochi - 0,5-1 PIECES / n'arọ ma obu 30-40 IGBOKWU 1-3 ugboro kwa ubochi, oburu na odi - ugboro 5-6 kwa ubochi. N ’ọgwụ kwa ụbọchị karịrị 0.6 U / n'arọ, a ga-enye insulin ahụ n’ụdị ntụtụ 2 ma ọ bụ karịa na akụkụ dị iche iche nke ahụ.
Ọ ga-ekwe omume ijikọta ya na insulins ndị na-eme ogologo oge.
A na - anakọta azịza insulin site na vial ahụ site na iji obere agịga na - egbu egbu na - ehichapu ọkpọkọ roba kpochapụrụ okpu aluminom na ethanol.
Ajuju, azịza, nyocha banyere ọgwụ Actrapid NM Penfill
Ihe omuma a enyere ndi okacha amara n’ulo ogwu. Ihe omuma nke kachasi banyere ogwu ahu di na ntuziaka nke ndi emeputaworo. Enweghị ozi edeputara na ibe a ma ọ bụ na saịtị ọ bụla ọzọ nwere ike ịnọchite anya arịrịọ nke onye ọkachamara.Mkparịta ụka ọgwụ ọjọọ
E nwere ọtụtụ ọgwụ na-emetụta mkpa maka insulin. Hypoglycemic mmetụta nke insulin welie onu hypoglycemic mmadụ, monoamine oxidase inhibitors, angiotensin n'ịtụgharị enzyme inhibitors, carbonic anhydrase inhibitors, nhọrọ beta-blockers, bromocriptine, sulfonamides, anabolic Steroid, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, ọgwụ ọjọọ lithium salicylates .
Mmetụta hypoglycemic nke insulin na-ebelata site na mgbochi mgbochi nke ọnụ, glucocorticosteroids, homonụ thyroid, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, hormone hormone (somatropin), danazol, clonidine, ngwa ngwa calcium channel blozox, diafenin, diafenin.
Ndị na-egbochi beta nwere ike kpuchie mgbaàmà nke hypoglycemia ma mee ka o sie ike naghachi hypoglycemia.
Octreotide / lanreotide nwere ike ịbawanye ma wedata mkpa ahụ insulin nwere.
Mmanya na-egbu egbu nwere ike iwelie ma ọ bụ ibelata mmetụta hypoglycemic nke insulin.
Actrapid ® NM ka enwere ike itinye ya na ogige ndị ahụ nke amaara na ya dakọtara. Drugsfọdụ ọgwụ (dịka ọmụmaatụ, ọgwụ nwere thiols ma ọ bụ sọlfite) mgbe agbakwunye na ngwọta nke insulin nwere ike ibute imebi.
Ọnọdụ nchekwa maka ọgwụ
Debe ọgwụ ahụ na okpomọkụ nke 2 Celsius 8 ruo 8 Celsius (na friji), mana ọ bụghị n'akụkụ friza. Emela ifriizi. Debe katọn n'ime igbe kaadi ọ bụla iji chebe ọkụ.
Maka mepere emepe:
- Echekwala na friji. Chekwaa na nju okpomọkụ agaghị akarị 30 Celsius C maka izu isii.
Ekwesịrị ka echekwa ihe Njirimara NM Penfill from ka ọ ghara ịkari oke ọkụ na ọkụ. Ekwela ka ụmụaka ghara iru ya.
Ntụziaka maka ojiji
Dabere na ntuziaka maka ojiji, dose nke Actrapid NM bụ nke dọkịta kpebiri kpebie n'ọnọdụ ọ bụla dabere n'ọnọdụ onye ọrịa ahụ. Mgbe ị na-eji Actrapid NM n'ụdị ya dị ọcha, a na-edekarị ya ugboro atọ n'ụbọchị (ikekwe ruo ugboro 5-6). Enwere ike ịnye ọgwụ ahụ subcutaneously, intramuscularly ma ọ bụ intravenously.
N'ime nkeji iri atọ mgbe ị administrationụ ọgwụ ahụ gasịrị, ị ga-eri nri. Site na nhọrọ insulin nke onwe ya, ọ ga-ekwe omume iji Actrapid NM yana njikọ insulins na-adị ogologo oge. Enwere ike ịgwakọta Actrapid NM n'otu sirinji ya na insulins ndị ọzọ dị ọcha. Mgbe agwakọtara ya na ọgwụ insulin nke insulin, a ghaghị ime ya ozugbo. Mgbe agwakọtara ya na insulins na-eme ogologo oge, a ga-ebu ụzọ HM actrapid banye ntụtụ.
Iji corticosteroids, MAO inhibitors, mgbochi nke homonụ, mmanya, ọgwụgwọ na homonụ thyroid nwere ike ibute mmụba na mkpa insulin.
Hụrụ onye iro a swornụrụ iyi MUSHROOM nke mbọ! A ga-asacha mbọ gị na ụbọchị 3! Were ya.
Kedu otu esi eme ka nrụgide olu ike ngwa ngwa mgbe afọ 40 gasịrị? Ntụziaka ahụ dị mfe, dee ya.
Ike gwụrụ ọbara? E nwere ụzọ mgbapụ! Enwere ike ịgwọ ya n’ụlọ n’ụlọ ụbọchị ole na ole, ịkwesịrị.
Banyere ọnụnọ ikpuru na-ekwu ODOR site n'ọnụ ya! Otu ugboro n'ụbọchị, aụọ mmiri nwere mmiri iji ..
