Humalog - ntuziaka maka ojiji, analogs, nyocha na ụdị mwepụta (QuickPen pen syringe nwere ngwọta ma ọ bụ nkwusioru nke Mix 25 na 50 insulin) nke ọgwụ maka ịgwọ ụdị 1 na ụdị shuga 2 na ndị okenye, ụmụaka na n'oge ime.

N'isiokwu a, ị nwere ike gụọ ntuziaka maka iji ọgwụ Isi Okwu. Na-enye nzaghachi site n'aka ndị ọbịa na saịtị ahụ - ndị na-eri ọgwụ a, yana echiche nke ndị ọkachamara n'ịgwọ ọrịa gbasara iji Humalog na omume ha. Nnukwu arịrịọ bụ ka ịgbakwunye nyocha gị gbasara ọgwụ ahụ: ọgwụ ahụ nyeere aka ma ọ bụ enyereghị aka iwepụ ọrịa ahụ, ihe nsogbu na nsonaazụ ndị a hụrụ, ikekwe ọ bụ ọkwa onye nrụpụta na nkọwapụta. Analogs nke Humalog n'ihu ọnụnọ analogues dịnụ. Jiri maka ọgwụgwọ maka ụdị 1 na ụdị ọrịa shuga mellitus 2 (nke na-arịa insulin na-arịa ọrịa shuga na-enweghị insulin) na ndị okenye, ụmụaka, yana n'oge ime na lactation. Ngwakọta ọgwụ ahụ.

Isi Okwu - ntụnyere nke insulin mmadụ, dị iche na ya site na usoro nke proline na nsị nke amị acid na ọnọdụ 28 na 29 nke yinye insulin B. E jiri ya tụnyere insulin na-eme obere oge, a na-eji insulin lyspro ngwa ngwa mmalite na njedebe nke nsonaazụ, nke a bụ n'ihi mmụba dị ukwuu site na ọdụ nke subcutaneous n'ihi nchedo nke monomeric tsari nke ụmụ irighiri insulin insulin na ngwọta. Mmalite nke ọrụ bụ nkeji iri na ise mgbe nchịkwa subcutaneous gasịrị, oke kachasị na-adị n'agbata awa 0,5 na awa 2.5, oge ọrụ ga-abụ awa 3-4.

Humalog Mix bụ ihe ana - eme ka mmadụ nwee insulin n’onwe ya ma ọ bụ ngwakọta emepụtara nke nwere insulin insulin lyspro (nke na - eme ngwa ngwa nke insulin na - arụ ọrụ) na nkwụsị nke insulin protinine protinine nke na - arụ ọrụ mmadụ.

Ihe bụ ọrụ insulin lyspro bụ nhazi nke metabolism metabolism. Na mgbakwunye, ọ nwere anabolic na mgbochi catabolic na anụ ahụ dị iche iche. Na akwara anụ ahụ, enwere mmụba nke ọdịnaya glycogen, abụba abụba, glycerol, mmụba nke njikọ protein na mmụba nke amino acid, mana n'otu oge ahụ enwere mbelata nke glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, catabolism protein na ntọhapụ nke amino acid.

Ngwakọta

Nnukwu insulin + insulin.

Mlọ ọgwụ

Njuputa nke nnabata na mmalite nke mmetụta nke insulin na-adabere na saịtị ịgba ọgwụ (afọ, apata ụkwụ, ụkwụ), dose (olu insulin insulin), na itinye uche nke insulin na nkwadebe. A na-ekesa ya n’akpụ akwara. Ọ dịghị agafe ihe mgbochi placental na mmiri ara. Ọ bụ insulinase na-abụkarị imeju ya na akụrụ. Ọ bụ ya mere akụrụ - 30-80%.

Ihe na-egosi

ụdị 1 ọrịa shuga mellitus (insulin-based), gụnyere na ntachi obi na nhazi insulin ndị ọzọ, ya na postprandial hyperglycemia nke na-enweghị ike imezi insulin ndị ọzọ, nnukwute insulin na-egbochi insulin (emebi emebi insulin nke mpaghara).
ụdị 2 ọrịa shuga mellitus (nke na-abụghị insulin): na iguzogide ọgwụ hypoglycemic nke ọnụ, yana ịnwe mmịnye nke nkwadebe insulin ndị ọzọ, hyperglycemia postprandial na-enweghị ọgwụgwọ, n'oge arụ ọrụ, ọrịa na-efe efe.

Dị Mwepụta

Ngwọta maka nchịkwa intraaneous na subcutaneous nke 100 IU na katalọgụ 3 ml agbakwunyere na ngwa ngwa plọgPP ma ọ bụ sịnye pen.

Nkwụsị maka nchịkwa subcutaneous 100 IU na ngwongwo 3 ml nke eserese n'ime QuickPen pen ma ọ bụ sịnye mkpịsị (Humalog Mix 25 na 50).

Formsdị usoro ọgwụgwọ ọzọ, ma ọ bụ mbadamba ma ọ bụ okpu.

Ntụziaka maka ojiji na usoro ojiji

Usoro ịtọ usoro atọrọ n’otu n’otu. A na - enye insulin Lyspro subcutaneously, intramuscularly ma ọ bụ intravenously 5-15 nkeji tupu nri. Otu ngaji bụ nkeji iri anọ, a na-ahapụ ike karịa naanị n'ọnọdụ ọke. Site na monotherapy, a na-ahụ insulin Lyspro ugboro 4-6 kwa ụbọchị yana mgbakwunye insulin ogologo oge - ugboro atọ kwa ụbọchị.

Ọgwụ a kwesịrị iji subcutaneously.

Usoro ọgwụgwọ intravenous nke ọgwụ Humalog Mix bụ contraindicated.

Okpomọkụ dị iche iche nke ọgwụ a na-elekọta kwesịrị ịdị na n ụlọ ahụ.

Ekwesịrị ịbanye n'akụkụ ubu, apata ụkwụ, ihe mkpuchi ma ọ bụ afọ. Ekwesịrị ịgbanye saịtị ndị injection ahụ ka ejiri otu ebe ahụ karịa oge 1 kwa ọnwa. Mgbe s / na ntinye ọgwụ Humalog, a ga-akpachara anya iji zere itinye ọgwụ ahụ n'ime arịa ọbara. Mgbe ogwu ogbugba gasịrị, ekwesighi ịhịa aka ntụtụ.

Mgbe ị na-etinye katriiki na ngwaọrụ ntụtụ insulin ma na-etinye agịga tupu nchịkwa insulin, a ga-enyocharịrị ndụmọdụ nke onye rụpụtara ngwaọrụ nchịkwa insulin.

Iwu maka iwebata ọgwụ Humalog Mix

Nkwadebe maka okwu mmeghe

Ozugbo ejiri ya, ekwesịrị ịmegharị ngwakọta nke Humalog Mix n'etiti nkwụ n'agbata ya ugboro iri wee maa jijiji, na-atụgharị 180 Celsius ugboro iri iji weghachite insulin ruo mgbe ọ dị ka mmiri mmiri ma ọ bụ mmiri ara ehi na-agakọ. Ikwanye ike, dika nke a nwere ike ibute ụfụfụ, nke nwere ike igbochi ọgwụ kwesịrị ekwesị. Iji mee ka agwakọta, katrijia nwere obere ite bekee. Ekwesighi iji ọgwụ a ma ọ bụrụ na enwere flakes mgbe agwakọta.

Etu esi eji ogwu a

Saa aka.
Họrọ ebe igba ogwu.
Jiri ọgwụ antiseptik mee ntụtụ ahụ (iji ntụtụ onwe gị, dabere na ndụmọdụ dọkịta).
Wepu okpu nchebe na agịga.
Mezie anụ ahụ site na ịdọrọ ya ma ọ bụ jidere nnukwu ogige.
Fanye agịga dị n'okpuru ala ma rụọ ntụtụ ahụ dabere na ntuziaka maka iji mkpịsị edemede.
Wepu agịga ahụ ma jiri nwayọ ghee saịtị ntụtụ ahụ ruo sekọnd ole na ole. Etekwala ebe a na-agba ntụtụ.
Iji okpu nchebe nke mpụga ahụ, yọpụ agịga ahụ ma bibie ya.
Tinye okpu na pen sirinji.

Mmetụta akụkụ

hypoglycemia (nnukwu hypoglycemia nwere ike ibute ọnwụ na, mgbe ụfọdụ, ọnwụ),
ọnya na-acha ọbara ọbara, ọzịza, ma ọ bụ ọnya ọnya na saịtị ahụ (ọ na-apụkarị mgbe ụbọchị ole na ole ma ọ bụ izu ole na ole, n'ọnọdụ ụfọdụ, enwere ike ibute mmeghachi omume ndị a site n'ihe ndị metụtara insulin, dịka ọmụmaatụ, iwe anụ ahụ site na antiseptik ma ọ bụ ọgwụ na-adịghị mma),
juputara itching
iku ume ike
mkpụkpu ume
ọbara mgbali elu,
tachycardia
amata aja aja
mmepe nke lipodystrophy na ntinye ebe.

Ihe ngbanwe

hypoglycemia,
hypersensitivity na mmiri ọgwụ.

Ime na lactation

Ruo ugbu a, enweghị mmetụta Lyspro insulin na-atụrụ ime ma ọ bụ ọnọdụ nwa ebu n’afọ na amụrụ.

Ebumnuche nke ọgwụ insulin n'oge ime bụ ijikwa glucose zuru oke. Mkpa insulin na-agbadata na ọkara nke mbụ ma na-abawanye n'ime oge nke abụọ na nke atọ nke afọ ime. N'oge na mgbe amuchara nwa, ihe ndi choro insulin nwere ike igbadata nke ukwuu.

Womenmụ nwanyị ịmụ nwa na-arịa ọrịa shuga kwesịrị ịgwa dọkịta banyere mmalite dị ma ọ bụ atụmatụ ime.

N'ime ndị ọrịa nwere ọrịa mellitus n'oge ị na-a breastụ ara, enwere ike ịchọ mgbanwe insulin na / ma ọ bụ nri.

Ntụziaka pụrụ iche

Ekwesịrị ị hụ nlezianya ụzọ nchịkwa nke achọrọ maka ụdị ọgwụ insịkal ọ bụla. Mgbe ị na-ebufe ndị ọrịa na nnabata insulin na-eme ngwa ngwa nke ụmụ anụmanụ na insulin lispro, enwere ike ịchọ mgbanwe mgbanwe dose. A na-atụ aro ibugharị ndị ọrịa na-anata insulin kwa ụbọchị nke gafere ogo 100 site n'otu ụdị insulin gaa na nke ọzọ ka a gaa ụlọ ọgwụ.

Mkpa insulin nwere ike ịba ụba n'oge ọrịa na-efe efe, na-enwe nchekasị mmetụta uche, na-abawanye ụba nke carbohydrates na nri, n'oge ị additionalụ ọgwụ ndị ọzọ na ọrụ hyperglycemic (homonụ thyroid, glucocorticoids, mgbochi ogwu, ọgwụ mgbochi, thiazide diuretics).

Mkpa insulin nwere ike ibelata site na akụrụ na / ma ọ bụ imeju, yana mbelata nke carbohydrates na nri, yana mgbatị anụ ahụ, n'oge mgbakwunye ọgwụ ndị ọzọ nwere ọrụ hypoglycemic (ndị na-egbochi MAO, ndị na-abụghị ndị na-ahọrọ beta-blockers, sulfonamides).

Enwere ike imezi hypoglycemia n'ụdị nnukwu ọrịa site na iji m / m na / ma ọ bụ nchịkwa s / c nke glucagon ma ọ bụ nchịkwa glucose.

Mkparịta ụka ọgwụ ọjọọ

A na - eme ka mmetụta hypoglycemic nke Lyspro insulin dị na MAO inhibitors, ndị na - ahọrọ beta-mgbochi, sulfonamides, acarbose, ethanol (mmanya) na ọgwụ ethanol nwere.

A na-ebelata hypoglycemic mmetụta nke Lyspro insulin na glucocorticosteroids (GCS), homonụ thyroid, mgbochi mkpị, thiazide diuretics, diazoxide, antidepressants tricyclic.

Beta-blockers, clonidine, reserpine nwere ike kpuchie ngosipụta nke ọrịa hypoglycemia.

Analogs nke ọgwụ Humalog

Anakpụrụ nke analogues nke na-arụ ọrụ: