Thiogammacene, chọta, zụta

Aha ahia ogwu: Thiogamma

International Nonproprietary Aha: Thioctic acid

Usoro onunu ogwu: mbadamba, ihe ngwọta maka nchịkwa infusion, tinye uche maka nkwadebe nke ngwọta infusion

Arụ Ọrụ: thioctic acid

Ndị na-ere ọgwụ:

metabolism nke metabolism na-egbu ume

Ngwá ọgwụ ọgwụ:

Thiogamma-Turbo na-arụ ọrụ bụ acid thioctic (alfa-lipoic) acid. A na-eme acid acid n’ime ahụ ma rụọ ọrụ dịka coenzyme maka ume metabolism nke alpha-keto acid site na decarboxylation oxidative. Thioctic acid na - eduga n'ịbelata glucose na ọbara ọbara, na - enye aka na nchịkọta nke glycogen na hepatocytes. A na-ahụta ọgba aghara nke metabolism ma ọ bụ enweghị thioctic acid na nchịkọta nke ụfọdụ metabolites na ahụ (dịka ọmụmaatụ, ahụ ketone) yana yana mmanya. Nke a na - eduga n'ọgba aghara na yinye aerobic glycolysis. Thioctic acid dị na anụ ahụ n'ụdị 2: belata na oxidized. Bothdị abụọ a na-arụ ọrụ physiologically, na-enye antioxidant na mgbochi na-egbu egbu.

Acid Thioctic na-achịkwa metabolism nke carbohydrates na abụba, na-emetụta metabolism nke cholesterol n'ụzọ dị mma, nwere mmetụta hepatoprotective, na-eme ka ọrụ imeju dịkwuo mma. Mmetụta bara uru na usoro mmeghachi azụ na akwara na akwara. Ngwongwo ọgwụ nke thioctic acid yiri nke vitamin B .. N’oge mbu site na imeju, thioctic acid na-eme mgbanwe ndị dị mkpa. Na sistemụ ọgwụ ahụ siri ike, a na-ahụ mgbanwe ndị mmadụ n'otu n'otu.

Mgbe ejiri ya n'ime, ọ na-adị ngwa ngwa ma ọ bụrụhaala kpamkpam na usoro nri. Metabolism na - aga n'ihu site na iji sọks nke akụkụ ụrọ nke thioctic acid na conjugation ya. Mwepu ọkara ndụ Tiogamma (Tiogamma-Turbo) sitere na minit 10 ruo 20. Kpochasịrị mmamịrị, yana metabolites nke thioctic acid.

Ihe ngosi maka ojiji:

Polyneuropathy na-arịa ọrịa mamịrị, polyneuropathy na-egbu egbu.

Contraindications:

Ime ime, inye nwa ara (ndi na aru ara), umuaka noo n’agbata afo iri na ano n’ato, hypotensitivity to thioctic acid ma obu ihe ndi ozo na ogwu.

Usoro usoro onunu ogwu

Thiogamma maka nchịkwa parenteral.

Ezubere nke Thiogamma maka ochichi parenteral site na infupiresive drip infusion. Maka ndị okenye, a na-etinye 600 mg (ọdịnaya nke vial ma ọ bụ 1 ampoule) otu ugboro n'ụbọchị. A na-eme infusion ahụ nwayọ nwayọ, maka minit 20-30. Usoro ọgwụgwọ dị ihe dị ka izu abụọ na anọ. N'ọdịnihu, a na-atụ aro ka ime ihe nke Tiogamma na mbadamba nkume. Edebere ochichi Parenteral Thiogamma maka infusion ka edepụtara maka nnukwu nsogbu nke uche nke metụtara polyneuropathy mamịrị.

A na-agbanye ọdịnaya nke karama 1 nke Thiogamma-Turbo ma ọ bụ 1 ampoule nke Thiogamma (600 mg nke ọgwụ) na 50-250 ml nke 0.9% sodium chloride solution. Ọnụego mgbakwunye intravenous - ọ bụghị ihe karịrị 50 mg nke thioctic acid na nkeji 1 - nke a kwekọrọ na 1.7 ml nke ngwọta Tiogamma. Ekwesịrị iji nkwadebe dilution ozugbo agwakọta ya na ihe mgbaze. N'oge ọgbụgba, a ga - eji ihe pụrụ iche na - echebe ọkụ si na ọkụ.

Mbadamba mbadamba ihe eji eme ihe. A na-atụ aro ịkọ ọgwụ 600 mg nke ọgwụ 1 oge kwa ụbọchị. A ga-elo mbadamba ihe niile kpamkpam, were ya n'agbanyeghị nri, were mmiri zuru oke sachaa ya. Ogologo oge ọgwụ ọgwụ sitere na 1 ruo ọnwa anọ.

Mmetụta:

Sistemụ akwara Central: n’ọnọdụ ndị a na-adịghị ahụkebe, ozugbo ị ofụ ọgwụ n’ụdị nke infusion, mkpịsị akwara na-emegharị ahụ.

Akụkụ Sense: imebi mmetụta nke uto, diplopia.

Sistem hematopoietic: purpura (ọrịa mbufụt), thrombophlebitis.

Mmeghachi omume hypersensitivity: usoro mmeghachi omume nwere ike ibute ujo anacticlactic, eczema ma ọ bụ urticaria na ntụtụ.

Usoro nri (maka mbadamba Tiogamma): ngosiputa nke dyspeptik.

Ndị ọzọ: ọ bụrụ na a na-achịkwa Tiogamma-Turbo (ma ọ bụ Tiogamma maka nchịkwa parenteral) ngwa ngwa, ịda mbà iku ume na mmetụta ntachi obi na isi ahụ ga - ekwe omume - mmeghachi omume ndị a na-akwụsị mgbe mbelata nke ọnụego. Possible nwekwara ike: hypoglycemia, fla ọkụ, ọgbụgba, ọsụsọ, obi mgbu, mgbada ọbara, ọgbụgbọ, ọhụhụ isi ọwụwa, isi ọwụwa, vomiting, tachycardia.

Mmekọrịta na ọgwụ ndị ọzọ:

Thioctic acid na-ebelata ịdị irè nke cisplatin mgbe ị na-ewere ya, na-ejikwa ọgwụ ndị nwere metal, dị ka iron, magnesium eme ihe.

Thioctic acid na-emeghachi na ụmụ irighiri shuga iji mepụta ogige ọgwụ ndị na-egbu egbu, dịka ọmụmaatụ, nwere usoro nke levulose (fructose).

Acid Thioctic na - akwalite mmetụta mgbochi mkpali nke GCS.

Site na oge nke thioctic acid na insulin ma ọ bụ ọgwụ hypoglycemic ọgwụ, enwere ike ịbawanye nsonaazụ ha.

Ethanol na metabolites ya na-ebelata ike nke thioctic acid.

Ngwakọta ngwakọta thioctic acid na-ekwekọ ekwekọ usoro dextrose, Ngwọta Ringer, na ihe ngwọta na-emeghachi na ìgwè disulfide na SH.

Exbọchị mmebi: 5 afọ

Usoro ahịa ọgwụ ahịa: site na ndenye ọgwụ

Emeputa:

Werwag Pharma GmbH & Co. KG (Worwag Pharma GmbH & Co. KG), Beblingen, Germany.