Insulin nsogbu (inyocha mkpụrụ ndụ ihe nketa mmadụ): ngwa

A na-eji ya agwọ ụdị ọrịa shuga niile. Nyere ụmụ nwanyị dị ime aka, ọ bụrụ na ọgwụgwọ nri anaghị enye nsonaazụ yana yana mgbe ha mụsịrị nwa. Insulin ọgwụ mmadụ na-agbanwe agbanwe na-arụkwa ọrụ na arụ ọrụ, mmerụ ahụ, ọrịa na-efe efe, nke fever na-esonyere ya.

Naanị dọkịta nwere ike inye gị usoro ị administrationụ ọgwụ ahụ na usoro nchịkwa nke ọgwụ ahụ, ebe ọ bụ na n'ọnọdụ ọ bụla ọ dabere na njirimara mmadụ n'otu n'otu nke ọrịa ahụ.

Ọtụtụ mgbe, ọgwụ ntụtụ na - eme subcutaneously, minit 15-30 tupu nri. Nwekwara ike banye intravenously intramuscularly. Nọmba ọkọlọtọ nke injections bụ ugboro 3 kwa ụbọchị. Ngwa ngwa tupu igba ogwu ahụ, ịkwesịrị ijide n’aka na karama nwere ọgwụ ahụ dị n ’ụlọ ahụ, na mmiri dị n’ime ya enweghị nsogbu ọ bụla. A nabataghị iji ọgwụ ahụ na ụdị opacities niile.

Imeghari insulin ọ̀hụnwuru ọ̀bara ọ bụrụ na imebi ahụ mmadụ, ọ bụrụ na achọpụta:

ọrịa na-efe efe
nsogbu thyroid
Ọrịa Addison
hypopituitarism,
ọrịa shuga n’ime ndị karịrị afọ 65.

Ọbara glucose nwere ike ịda nke ọma maka ebumnuche ndị a:

mgbanwe mgbanwe ntanetị,
ịdoụ ọgwụ ọdoụ .ụ
mmega ahụ
nsogbu na eriri afọ
mmeghachi omume maka ojiji nke ọgwụ ndị ọzọ,
mgbe ị na-ebufe onye ọrịa na insulin mmadụ.

Laghachi na tebụl ọdịnaya

Enwere m mmasị (site na asụsụ Latin - insulin na ngwọta) nwere aha azụmahịa dị iche. Ọ dabere na oge nke ihe ahụ na usoro nrụpụta. Inweta insulin mmadụ na-aputa ihe n’ọkpụkpụ mmadụ, na-eji inyocha mkpụrụ ndụ ihe nketa. Ihe a na-ekpebi oge ọ ga-anọ. Enwekwara udiri - insulin nke abuo, ya na oge ekpughere ya. A na-ahụ iche otu ọgwụ dị iche iche:

Ogologo oge ikpughe Ngosipụta ihe atụ nke ọgwụ ọgwụ Mpempe nke obere ọgwụ Akara ihe izizi pụtara mgbe nkeji iri atọ gachara ka Humulin, Rinsulin, Gansulin na-egosipụta ọrụ na-amalite n’ime awa 2-3 Ihe ịrịba ama na-amalite n’ime elekere 1, ekpughere na - arụ ọrụ - 6 awa 6-7 “Boisulin” “Protafan” Mgbe awa 12 gachara, a na - ewepụ insulin kpamkpam site n'ahụ ahụ. ike ịgbanwe oge ọ ga-eji mezuo ahụ “Gansulin” “Gensulin” A na-anabata nnabata metụtara nri “Mikstard” Jiri ugboro abụọ n’ụbọchị, nkeji iri atọ tupu nri abịaghachi na tebụl ọdịnaya

Ọbara glucose dị ala, ịmịnye mmadụ ọbara bụ naanị ihe na-egbochi iji insulin eme ihe. Mmetụta ndị ọzọ bụ nfụkasị, n'ụdị urticaria, hypoglycemia. Also nwekwara ike dobe:

hypoglycemic coma,
nsogbu nke ụjọ na akwara ozi,
nsogbu n'okwu na anya,
ndaba,
hyperglycemia
ọzịza na ntụtụ ebe.

Laghachi na tebụl ọdịnaya

Insulin nke mmadụ (injinị mkpụrụ ndụ) emegideghị ọgwụ ndị ọzọ. Ọgwụ Sulfanilamide na ọgwụ steroid, yana tetracyclines, theophylline, quinidine, quinine, ethanol, na-ebelata oke glucose na ọbara. Kama nke ahụ, ọdịnaya ya na-abawanye: diuretics, homonụ thyroid, antidepressants, marijuana, nicotine, epinephrine, mgbochi igbochi ọnụ.

Akụkọ banyere otu n'ime ndị na - agụ akwụkwọ anyị, Inga Eremina:

Ibu m kacha nwee obi mgbawa, m dị ka ndị na-agba mgba atọ 3, nke bụ 92kg.

Kedu otu esi ewepụ oke ibu kpamkpam? Kedu otu esi anagide mgbanwe hormonal na oke ibu? Ma ọ dịghị ihe na-emebi ma ọ bụ ntorobịa mmadụ dịka mmadụ ya.

Ma ihe ị ga-eme iji felata? Surgerywa ahụ ọyịre laser? Achọpụtara m - opekata mpe ise. Usoro nchekwa - LPG ịhịa aka n'ahụ, cavitation, RF na-eweli elu, myostimulation? Obere ego karịa - usoro ahụ na-efu site na 80,000 rubles na onye ọkachamara n'ihe banyere nri. Can nwere ike gbaa mbọ gbaa ọsọ ma ọ bụrụ na ị na-enwe ara.

Na mgbe ị ga-ahụ oge a niile? Ee ma ka dịkwa oke ọnụ. Karịsịa ugbu a. Ya mere, maka onwe m, ahọpụtara m usoro ọzọ.

N'ihe banyere oke ị drugụ ọgwụ, mmadụ na-enwe agụụ, isi ọwụwa, ịma jijiji, ọbara mgbali ga-ebelata. Onye ọrịa ahụ dịka ọ dị n'ụra ụra. Na nmalite ọrịa ahụ, mmadụ na-eji aka ya wepụ akara ndị a. O zuru ezu ịri nri shuga dị elu, drinkụọ mmiri nwere carbonated. Ọ bụrụ na ịnwere ọgwụ “Glucagon” n’aka, nye ọgwụ mgbochi.

Mmekọrịta nke insulin na-agbari site na mkpụrụ ndụ ihe ọmụmụ ndị ọzọ

An anụbiga ọgwụ ókè, hypoglycemia na-amalite (ọsụsọ oyi, adịghị ike, anụ ahụ, ịma jijiji, palpitations, ụjọ, paresthesia n'ụkwụ, aka, ire, egbugbere ọnụ, agụụ, isi ọwụwa), cramps, hypoglycemic coma. Ọgwụgwọ: onye ọrịa ahụ nwere ike iwepụ hypoglycemia nwayọ site na itinye nri nri nwere nnukwu carbohydrates ma ọ bụ shuga. A na-edozi Glucagon subcutaneously, intravenously, intramuscularly, ma ọ bụ a na - edozi hypotonic dextrose solution intravenously, na hypoglycemic coma, 20-40 ml (ihe ruru 100 ml) nke 40% dextrose solution na - abanye n'ime intravenously ruo mgbe onye ọrịa ahụ hapụrụ Coma.

International Nonproprietary Aha (Ọrụ Na-arụ Ọrụ):

Ngwọta ogwu ntụtụ 3 ml - katriiki nke enweghị agba (5) - ngwungwu ngwakọ (1) - ngwugwu nke kaadiboodu.

A na-atụ aro ọgwụ ahụ maka iji ya na ọnọdụ ndị a:

- insulin na-arịa ọrịa shuga mellitus (ụdị 1),

- ọrịa mellitus na-arịa insulin na-abụghị insulin (ụdị 2): ọkwa nke iguzogide ndị nnọchianya hypoglycemic nke ọnụ, nguzogide akụkụ nke ọgwụ ndị a (n'oge ọgwụgwọ njikọta), yana ọrịa ọrịa, arụmọrụ, na ịtụrụ ime.

Ngwongwo ogwu

Insulin injinịa mmadụ na-ahụ maka nsogbu bụ nkwadebe insulin na-eme nwa oge. Ọ na-enweta otu nnabata kpọmkwem akpụkpọ ahụ dị na sel ahụ, ọgwụ ahụ mejupụtara ọgwụ nnabata insulin. Site na ịbawanye mmepụta nke cAMP (n’ime mkpụrụ ndụ akwara na mkpụrụ ndụ abụba) ma ọ bụ banye na sel, ihe ndị a na-akpali mkpali n’ọrụ n’ime sel, gụnyere ịmepụta ụfọdụ enzymes isi (pyruvate kinase, hexokinase, glycogen synthetase na ndị ọzọ). Mbelata glucose ọbara bụ n'ihi mmụba na nnabata site na anụ ahụ, mmụba nke ụgbọ njem intracellular, mkpali nke glycogenogenesis, lipogenesis, njikọ protein, mbelata ọnụego glucose na-emepụta site na imeju na usoro ndị ọzọ. Mgbe ejiri subcutaneously mee ihe, mmetụta nke ọgwụ ahụ na-etolite mgbe ihe dị ka nkeji 20 ruo 30, na-akacha karịa 1 ruo 3 awa ma dịruru 5 ruo 8 awa (dabere na dose). Ogologo oge ọgwụ a na-adabere na ebe yana usoro nchịkwa, dose ma kwupụta njirimara mmadụ. Izu oke nke ị ofụ ọgwụ ahụ dabere na ntinye, ebe injection (apata ụkwụ, afọ, isi), ụzọ nchịkwa (subcutaneous, intramuscularly), ọkwa insulin na ọgwụ ahụ, yana ihe ndị ọzọ. N’ime anụ ahụ, a na-ekesa ọgwụ ahụ n’esepụghị aka. Ọ bataghị na mmiri ara ara yana site na mgbochi placental. Ọ kachasị n'ime akụrụ na imeju, insulinase na-ebibi ya. Iwepu ọkara ndụ na-eme site na ọtụtụ ruo nkeji iri. 30 - 80% kpụrụ ya akụrụ.

Elldị shuga abụọ nke mellitus (ọkwa nke iguzogide ọgwụ hypoglycemic nke ọgwụ, nke na-eguzogide ọgwụ na hypoglycemic ọgwụ (ọgwụgwọ ejikọtara ọnụ)), ụdị shuga 1, hyperosmolar na ketoacidotic coma, ọrịa shuga na-arịa ketoacidosis, ọrịa shuga mellitus nke mepụtara n'oge afọ ime (na adịghị ike nke ọgwụgwọ nri) maka oge adịghị n'etiti ndị ọrịa na-arịa ọrịa shuga na-efe efe nke na-arịa ọbara mgbali elu, yana mmerụ ahụ na-abịanụ, ịwa ahụ na-amụ nwa, na nsogbu nke metabolic, tupu ịgbanwere ọgwụgwọ na nkwadebe insulin ogologo oge.

Thezọ maka ojiji nke insulin soluble mmadụ sitere na usoro ọmụmụ na usoro onunu ogwu

Uzo uzo ochichi na iguzogide ogwu a guzobere n’otu n’otu, n’ihe obula, dabere n’otinye glucose di n’ọbara tupu oge elekere 1 ruo 2 mgbe nri, ma dabere n’omume nke pathology na ogo nke glucosuria. A na-enye ọgwụ ahụ nkeji iri na ise ruo iri abụọ na ise tupu nri dị n'okpuru (ụzọ kachasị mma nke nchịkwa), intravenously, intramuscularly. Na coma shuga, ketoacidosis nke na-arịa ọrịa shuga, n'oge ịwa ahụ, intravenously na intramuscularly. Oge nchịkwa nke ọgwụ n'oge monotherapy na-abụkarị ugboro 3 kwa ụbọchị (ikekwe ruo ugboro 5-6 kwa ụbọchị, ma ọ bụrụ na ọ dị mkpa). Iji zere mmepe nke lipodystrophy (hypertrophy ma ọ bụ atrophy nke abụba subcutaneous), a ghaghị ịgbanwe saịtị injection oge ọ bụla. Nkezi ubochi ubochi bu 30 - 40 PIECES, maka umu - 8 ihe puru iche, mgbe ahuru na ubochi kwa ubochi - 0-1-1 ihe obula ma obu 30–40 PeriCES 1-3 ugboro nari, ikekwe rue ugboro 5-6 kwa ụbọchị, ọ bụrụ na ọ dị mkpa. Ọ bụrụ na ubochi kwa ụbọchị karịrị 0.6 U / n'arọ, mgbe ahụ ekwesịrị inye insulin n'ụdị 2 ma ọ bụ karịa injections n'akụkụ dị iche iche nke ahụ. Njikọ enwere ike yana insulins na-eme ogologo oge. A na-eji etinyere sịnịma robbes na etinyere ọgwụ insulin wee wepụ ya na ethanol mgbe etesịrị okpu aluminom ahụ.

Gbalịa ịlele ihe ngwọta maka nghọta tupu iwepuga insulin na vial ahụ. Enweghị ike iji ọgwụ ọjọọ eme ihe maka igwe ojii, ọdịdị nke ahụ ndị si mba ọzọ, ọdịda nke ihe dị na iko karama ahụ. Okpomoku nke ogwu eji eme ihe kwesiri ikwekọ na okpomoku ulo. Na ọrịa na-efe efe, ọrụ thyroid na-arụ ọrụ, hypopituitarism, ọrịa Addison, ọrịa shuga mellitus na ndị mmadụ karịa afọ 65 na ọdịda akụrụ na-adịghị ala ala, ọ dị mkpa iji dozie ọgwụ insulin. Ihe kpatara mmepe nke hypoglycemia nwere ike ịbụ: dochie ọgwụ, insulin overdose, nri nri, afọ ọsịsa, vomiting, nrụgide anụ ahụ, ngbanwe nke ntinye (afọ, afọ, ubu), ọrịa na-ebelata mkpa insulin (ọrịa ndị na-eto eto nke imeju na akụrụ, na yana hypofunction nke pituitary gland, adrenal cortex ma ọ bụ thyroid gland), mmekorita ya na ọgwụ ndị ọzọ. Enwere ike belata ọkwa glucose ọbara mgbe ị na-ebufe onye ọrịa site na insulin anụmanụ n'ime insulin mmadụ. Ekwesịrị ịnyefe onye ọrịa na insulin mmadụ naanị kwesịrị ịdị n'okpuru nlekọta dọkịta ma ekwesịrị ịkọwa ya na ọgwụ mgbe niile. Ebumnuche nke hypoglycemia nwere ike imebi ikike nke ndị ọrịa ịbanye na igwe ọrụ, yana ikerechi òkè na okporo ụzọ. Ndị ọrịa nwere ọrịa shuga nwere ike iwepụ hypoglycemia dị nwayọ site na ị eatingụ shuga ma ọ bụ ihe oriri nwere oke carbohydrates (ọ kacha mma ka gị na gị nwee shuga 20 g mgbe niile). Iji lebara okwu banyere mmezi ọgwụgwọ anya, ọ dị mkpa ịgwa dọkịta na-abịanụ banyere hypoglycemia gara aga. Mgbe ị na - eji insulin eme ihe dị mkpụmkpụ n'ọnọdụ ndị a na - adịghị ahụkebe, mmụba ma ọ bụ ibelata olu nke anụ ahụ adipose na ntụtụ mpụga ọ ga - ekwe omume. Site na-agbanwe saịtị ịgba ọgwụ mgbe niile, enwere ike izere lipodystrophy. N'oge afọ ime, ọ dị mkpa iburu n'uche mbelata (na ọkara nke atọ) ma ọ bụ mmụba (na nke abụọ na nke atọ) nke insulin chọrọ. Mkpa insulin nwere ike ibelata nke ukwuu n’oge a na-amụ nwa ma ozugbo ọ mụsịrị. N’ebe a na-enye nwa ara ehi, a choro nleba anya kwa ubochi rue otutu onwa (rue mgbe a choro insulin. Ndị ọrịa na-enweta ihe karịrị 100 IU nke insulin kwa ụbọchị chọrọ ịga ụlọ ọgwụ mgbe ha na-agbanwe ọgwụ.

Nsonaazụ nke insulin soluble sistemụ mmadụ

Mmeghachi omume nfụkasị (angioedema, urticaria, mkpụmkpụ ume, fever, iwetula ọbara).
hypoglycemia (ọsụsọ mụbara, pallor nke anụ ahụ, ịsa ahụ, maa jijiji, palpitations, agụụ, ụjọ, nhụjuanya, paresthesia n'ọnụ, ụra, isi ọwụwa, nsogbu ehighị ụra, ọnọdụ ịda mba, ụjọ, iwe, enweghị mmegharị, omume na-enweghị atụ, imerụ ahụ anya na okwu), akpịrị shuga hypoglycemic, nsụhọ uche (ruo n'ọkwa nke coma na precomatosis), ọrịa shuga acidosis na hyperglycemia (ya na injections, obere doses, nri na-adịghị mma, ọrịa, na ọrịa oradicum): akpịrị ịkpọ nkụ, ura, hyperemia nke ihu, mbelata agụụ, enweghi ike ịhụ ụzọ (tumadi na mmalite ọgwụgwọ), itching, hyperemia na lipodystrophy (hypertrophy ma ọ bụ atrophy nke subcutaneous adipose anụ ahụ) na ntinye ahụ, mụbara titer nke ọgwụ mgbochi insulin na mmụba na-abawanye mmeghachi omume immunological na insulin nke mmadụ, na mmalite ọgwụgwọ - mgbakasị ahụ siri ike na edema (ha na-adị nwa oge, na-ewepụ ya na ọgwụgwọ na-aga n'ihu).

Dodoụbiga ya ókè

Mmekọrịta na ọgwụ ndị ọzọ

Ihe omuma a di na peeji ahu sitere n’aka dibia ogwu Vasilieva E.I.

Etu ị ga-esi ahọrọ analọg ziri ezi
Na pharmacology, a na-ekekarị ọgwụ iji mee ka okwu na analogues. Ihe mejuputara ya bu otu uzo ma obu ozo si aru aru nke nwere aru oru aru. Site na analogs bu ogwu eji eme ihe nwere ihe ndi ozo di ndu, mana ebum n’obi iji gwọ oria otu oria a.

Ọdịiche dị n’etiti nje virus na nje
Ọ bụ nje virus, nje, fungi na protozoa na-ebute ọrịa ndị na-efe efe. Ọrịa na-ebute nje na nje na-abụkarị. Agbanyeghị, ịmata ihe kpatara ọrịa ahụ pụtara ịhọrọ usoro ọgwụgwọ dị mma ga-enyere aka ịnagide ọrịa ngwa ngwa na agaghị emerụ nwa ahụ.

Ihe nfụkasị bụ ihe na-akpata otutu oge
Peoplefọdụ ndị maara ọnọdụ nwatakịrị na-arịakarị ụfụ na ogologo oge. Ndị nne na nna na-akpọrọ ya gaa na nke ndị dọkịta, na-ele ule, na-a drugsụ ọgwụ ọjọọ, n'ihi ya, a na-edebanye aha nwatakịrị ahụ na dọkịta ụmụaka mgbe ọ na-arịa ọrịa. Amaghị ihe kpatara ọrịa ọrịa iku ume ugboro ugboro.

Urology: ọgwụgwọ chlamydial urethritis
Chlamydial urethritis na-ahụkarị n’omume urologist. Ọ bụ Chlamidia trachomatis nke nje intracellular, nke nwere akụrụngwa nke nje na nje, nke na-achọkarị ọgwụ mgbochi ogologo oge maka ọgwụgwọ antibacterial. O nwere ike ibute oke urera na ụmụ nwoke na ụmụ nwanyị.

Nchọpụta insulin nke inyocha mkpụrụ ndụ mmadụ: ntuziaka maka ojiji

Emepụtara insulin injinịa maka inyocha insulin na:

Idị nke m, ụdị shuga II: mgbe ọ gaghị ekwe omume ịchịkwa ọgwụ hypoglycemic nke ọgwụ ma ọ bụ enweghị ike ha
Ọrịa mamịrị ketoacidosis
Coma
Ọria mamiri n’oge afọ ime (ma ọ bụrụ na usoro ọgwụgwọ anaghị enyere aka)
Maka oge adịghị eji ndị ọrịa mamịrị megide nzụlite ọrịa na-efe efe na ọnya na-efe efe, na nkwadebe maka ịwa ahụ, mmerụ ahụ, ọrụ, nsogbu nke metabolic, yana mgbe ị na-agbanwe ka insulins dị ogologo.

Ihe insulin nke mmadu bu akuku nke ogwu site na ndi ozo di iche, ya mere ihe ntinye aka di iche na ibe ya.

Ahịa: 10 amp. 1 ml ọ bụla - site na 177 rub., Katrized 5 pcs. 3 ml -

1 ml ntụtụ nwere:

Ihe eji arụ ọrụ: 100 IU
Ihe ndi ozo: zinc chloride, glycerol, sodium hydroxide (ma obu hydrochloric acid), mmiri.

Ọgwụ n'ụzọ nke mmiri doro anya, edobereghị maka ojiji nke parenteral. Makọtara na ampoules, pen-syringes, karama.

Ihe dị mkpụmkpụ maka iji insulin na-adabere n'ụdị 1 ma ọ bụ ọrịa shuga 2. Mgbe ọ gbasara, ọ na-emeghachi omume na ndị na-anabata ya kpọmkwem na sel ahụ, nke na-eme ka e nwee nnukwu insulin-receptor complex, nke na-emekwa ka njikọ nke cAMP, usoro nke arụ ọrụ n'ime sel ahụ, gụnyere njikọ nke enzymes ndị dị mkpa.

Mbelata nke glycemia bụ n'ihi ụba njem, itinye n'ọrụ karịa, njikọta protein ngwa ngwa, yana imeju na -ewepụta glucose ngwa ngwa.

Mmepe nke hypoglycemic utịp ke ogwu ogbugba gosipụtara mgbe nkeji 15-30, na-eru ụkpụrụ kacha elu mgbe awa 1-3 na-adịgide, dabere na nha nke onunu ogwu. Ogologo oge nke ihe eji agbanye mkpụrụ ndụ ihe mejupụtara bụ ihe usoro dabere na oke, ebe na ụdị nchịkwa, yana njirimara nke ahụ onye ọrịa.

Ihe ahụ na-ekesasị n’akpụ akwara niile, ọ naghị agafe Plasenta na mmiri ara ehi. Ọ na-agbasa tumadi na imeju, akụrụ n'okpuru mmetụta nke insulinase. Ọpụpụ ahụ na-ewepụta ahụ.

A na-abanye insulin injin sitere na mkpụrụ ndụ mmadụ n'okpuru anụahụ ma ọ bụ na akwara nke veins. A họọrọ usoro onunu ogwu otu n'otu dabere na ọkwa glycemic. Ogologo ubochi kwesiri ogwu ahu bu 0.3-1 IU. N'ime ndị ọrịa nwere nguzogide insulin, ọ nwere ike ịdị elu, ma n'ime ndị nwere ihe nzuzo nke ihe ahụ, o nwere ike wedata ala.

A na-eme ọgwụ mgbochi ọkara ọkara tupu eri ma ọ bụ iwere ngwaahịa ndị nwere carbohydrate. Maka inje subcutaneous, họrọ mpaghara dị n'ihu mgbidi nke afọ ahụ, yana n'apata ụkwụ, ikpere ma ọ bụ akwara ike ọkpụkpụ. Maka okwu ndị dị ngwa ngwa, mgbe ọ dị mkpa ịgbanwe ngwa ngwa glycemia, ọ ka mma ịba n'ime afọ, ebe ọ bụ na a na-etinye insulin ngwa ngwa.

Ọ bụrụ na etinye ọgwụ ahụ n’akụkụ akpụkpọ ahụ, mgbe ahụ n’ọnọdụ a, ihe ize ndụ ịbanye n’arụ ahụ pere mpe. Iji gbochie mpụta ọgwụ ahụ, a na-atụ aro ka ọ dọpụta agịga maka 6-10 sekọnd. Maka ọgwụ mgbochi, ịkwesịrị iji mpaghara ọhụrụ oge ọ bụla iji zere imebi ihe akpukpo ahiri nke anụ ahụ na akwara.

Okwu mmeghe n’ime akwara chọrọ ịmata ihe puru iche na ahụmịhe bara ụba, yabụ, a na-anabata usoro ndị ahụ naanị maka ndị ọkachamara ahụike.

Tupu ị tụta ọ̀tọ insulin nke mepụtara site na vial ma ọ bụ ampoule, ịkwesịrị ijide n'aka na nghọta nke ntụtụ ahụ. Ọ bụrụ na enwere ihe ọ bụla dị na ya, kwụsịtụrụ ma ọ bụ ite nwere ọgwụ ahụ ga-agbụ, gbajisie ma ọ bụ rata, mgbe ahụ, a na-ewere ọgwụ ahụ ka ọ dị mma maka nchịkwa. Ekwesịrị ịchụpụ ya na usoro iwu anabatara.

Tupu ịgba ọgwụ mgbochi, ịkwesịrị kpoo ọgwụ ahụ n'ụzọ nkịtị ka ọnọdụ ya wee hara na ọnọdụ ụlọ.

Ọ ga-agbanwe usoro ogwu ahụ ma ọ bụrụ na onye ọrịa ahụ nwere ọrịa na-efe efe ma ọ bụ nsị thyroid. Idozigharị dịkwa mkpa maka ọrịa nke Addison, ịka nká, ụkọ nri, akwara gbasara akụrụ.

Anabataghị hypoglycemia. Mmepe ya na-ebute tupu iwebata insulin buru ibu na-ezighi ezi, nnọchi ọgwụ na-adịghị mma, nri iri nri, vomiting, afọ ọsịsa, oke anụ ahụ, imeju dị elu na / ma ọ bụ ọrịa akụrụ, nsị adrenal, yana ọgwụ ndị ọzọ. Na mgbakwunye, ọkwa nke glycemia nwere ike ibelata mgbe ị gbanwechara mpaghara ịgba agba, na-ebufe site na insulin anụmanụ. N'okwu nke abụọ, aga - ebugharị usoro ihe mmadụ nwere maka ebumnuche ọgwụ. Amachibidoro iji ọgwụ dochie ọgwụ ahụ.

Insulin insulin

AKKỌ: Nkwado homonụ pịkụkụkọ, ụmụ irighiri ihe mmadụ na-eme, nyocha nke mkpụrụ ndụ

Rp.: Insulini isophani 5ml (100ME)

S.: 20 ME subcutaneously 2 ugboro kwa ụbọchị.

MECHANISM: na - etolite insulin receptor complex na akpụkpọ ahụ, na - eme ka cAMP dịkwuo elu, na - akpali njikọ nke enzymes (hexokinase, wdg). Mbelata nke mkpokọta glucose na ọbara n'ihi mmụba nke nsị akwara ya (nnabata site na akwara), mkpali nke lipogenesis, glycogenogenesis, na mbelata nke mmepụta glucose site na imeju (ibelata na mmebi nke glycogen).

Esemokwu: T1DM, T2DM: ogbo nke igbochi ọnụ, ọrịa na - efe efe, T2DM n'ime ụmụ nwanyị dị ime.

AKTRKỌ: HS, hypoglycemia.

KID:Mmetụta na mgbanwe U: hypoglycemia (pallor nke anụ ahụ, ịba ụba ọsụsọ, palpitations, ịma jijiji, agụụ, oke iwe, paresthesia n'ọnụ, gb, hypoglycemic coma).Mmeghachi omume nfụkasị ahụ: osisa aru, ekpukpu nke Quincke. Ndị ọzọ: ọzịza, njehie na-efegharị ugboro ugboro. Mmeghachi omume mpaghara: hyperemia, ọzịza na itching na ntụtụ ahụ, yana iji ogologo oge - lipodystrophy na saịtị ahụ.

AKKỌ: ọgwụ antidiabetic na-eme ihe, ọgwụ insulin na-ebelata ihe ndị na-emetụta ya, biguanides

Rp.: Tabl. Metformini 0,5

S.: 1 mbadamba 2 (ma ọ bụ 1) otu ugboro n'ụbọchị (na mgbede) mgbe nri gasịrị.

MECHANISM: na-abawanye ọgụgụ insulin, na-akpali ijide glucose site na akwara ọkpụkpụ, na-akpali anaerobic glycolysis, na-ebelata glucose na-emetụta ya na imeju ya, na-ebelata glucagon na ọbara na LDL, cholesterol, na triglycerides, na-ebelata agụụ na aru.

Esemokwu: T2DM (ọkachasị maka oke ibu) na ọdịda nri.

AKTRKỌ: HF, akụrụ / akwara / iku ume / nkụchi obi, nkụchi obi, anaemia, akpịrị ịkpọ nkụ, ọrịa na-efe efe, mmanya na-egbu egbu, metabolic acidosis, ịtụrụ ime, lactation.

KID: GIT: na nmalite - anorexia, afọ ọsịsa, ọgbụgbọ, ọgbụgbọ, flatulence, ime ime, ụtọ dị n’ime ọnụ. CCC: megaloblastic anaemia. Metabolism: hypoglycemia, adịkarịghị lactic acidosis (adịghị ike, iro ụra, hypotension, bradyarrhythmia na-eguzogide, nsogbu iku ume, mgbu afọ, myalgia, hypothermia). Akpụ: ihe odide, ọnya afọ.