Thioctic acid

Ihe antioxidants bụ ihe na - egbochi mmeghachi nke oxidative. Ihe ngborogwu nke ha na agha megide otutu usoro nebe ahu. Ha anaghị anabata mmepe nke ọrịa kansa, ọrịa obi. N'ime ihe ndị nwere arịa ndị a bụ acidum thiocticum. Ntụziaka maka iji thioctic acid (ntụgharị okwu ahụ si na Latin) na-ekwu na nke a bụ naanị otu n'ime ọrụ ole na ole nke ogige a.

Ngwa

Thioctic ma ọ bụ lipoic acid bụ ihe na-arụ ọrụ bio bio nke e leburu na mbụ dịka vitamin. Ma mgbe omumuchara ihe omumu zuru oke, etinyere ya n’etiti vitamin nke gosiputara ihe ogwu. N'ime akwụkwọ ahụike, a na-ahụ aha Vitamin N.

Dịka antioxidant, acid a na-ejikọ thioctic. Site na nsonaazụ ya na anụ ahụ, ọ dị ka vitamin nke otu B. Ihe ahụ na-egosipụta nhụchasị na njirimara hepatoprotective.

Polysaccharide a bụ ụdị bụ isi na - echekwa ihe ikpeazụ ma nweekwa carbohydrate. Ọ na-emebi n'ike nke enzymes mgbe ọkwa shuga belatara, dịka ọmụmaatụ, n'oge mgbatị anụ ahụ. Acid na-ebelata ohere nke ọrịa shuga mellitus dị ize ndụ - nsogbu na-arụ ọrụ nke sistem ụjọ, obi na akwara ọbara.

Mgbe nlekọta nchịkwa gasịrị, a na-etinye obi gị dum na eriri afọ. A na-achọpụta oge kachasị mgbe oge nkeji 25 ruo 1 elekere. Ogo nke bioavailability sitere na 30 ruo 60%. A na-ekepụta Lipoic acid n'ụdị metabolites site na akụrụ.

Megide cholesterol na oke ibu

Lipoic acid na -ebelata oke nke cholesterol dị n'ọbara, ebe ọ bụ na ọ na-ekere òkè na metabolism abụba ma bụrụ ihe dị mkpa na-ekere òkè na ya. A na-egosipụta mmetụta hypocholesterolemic ma ọ bụrụ na vitamin zuru ezu na-abanye ahụ. Ọgwụ na-egbochikwa agụụ. Nke a na - egbochi oke ibu ma mee ka ọ dịkwuo ike.

Na ọgwụgwọ nke ọrịa vaskụla

Site n'idegide uru nke thioctic acid n'ime ahụ, ọ ga-ekwe omume belata ohere nke ịmalite ọrịa obi, gụnyere ọnya na nkụchi obi. N'ime ndị ọrịa nwere ụdị nchọpụta ahụ, ọgwụ ahụ na-ebelata nsonaazụ nke ọrịa ahụ ma na-egbochi nsogbu ndị dị ize ndụ.

Ọgwụ na-eme ka oge mmegharị ahụ dịkwuo elu, na-enye aka iwughachi miri emi nke ọrụ anụ ahụ mgbe ọrịa strok gachara. N'okwu a, ogo paresis (ahụ mkpọnwụ na-ezughị ezu) yana ịrụ ọrụ nke akwara ozi ụbụrụ belata.

A na-eji acid Thioctic acid mee ihe maka polyneuropathy (ọrịa shuga, onye aholicụrụma), na-egbu nsị, karịchaa, nke nwere nnu dị arọ, griiz. Ọgwụ dị irè na ọrịa pathologies:

• ọrịa ịba ọcha n'anya A, ịba ọcha n'anya,
• mmebi abuba,
• cirrhosis.

Edere Vitamin N maka hyperlipidemia, nke a chọpụtara na ọrịa obi na-arịa atherosclerosis, maka oke ibu.

Ihe ngbanwe

A naghị eji Thioctic acid mee ihe maka ọgwụgwọ n'okpuru ọnọdụ ndị a:

• hypersensitivity na lipoic acid ma ọ bụ ihe ndị ọzọ dị na ọgwụ ahụ, ka lactose,
• onye ọrịa ahụ erughi afọ 6, were usoro onunu ogwu nke 600 mg - afọ 18.

Na neuropathy siri ike kpatara ọrịa shuga mellitus, a na-enye acid thioctonic intravenously na 300-600 mg. A na-enweta ọgwụ mgbochi site na ntụtụ ma ọ bụ ntapu mmiri. Ọ dịruru izu 2-4. A ga-edoziri mpempe mbadamba ihe.

Dabere na usoro ọgwụgwọ ahụ ka dọkịta kpebiri, onye na-eburu n'uche ogo ọrịa ahụ na ọnọdụ onye ọrịa ahụ.

Oge opekempe nke ọgwụgwọ bụ izu iri na abụọ. Dabere na mkpebi ndị dọkịta si kwuo, a na-aga n’ihu ahụ ruo mgbe ha rụpụtara ihe a tụrụ anya ya.

Mmetụta akụkụ

Ọ bụ ezie na ndepụta nke mmeghachi omume ọjọọ na-esite na iji ọgwụ a dị mkpụmkpụ, ị kwesịrị ịmara banyere ya.

N'oge usoro ọgwụgwọ, mmeghachi omume ndị dị otú ahụ na-apụta:

• mgbe ingesed - nsogbu nke nri, gosipụtara ya site na ọgbụgbọ, ọgbụgbọ, stools, yana mgbu nke afọ,
• ihe mgbaàmà nke hyperreaction - ihe ọkụ ọkụ na epidermis, urticaria, ujo ụjọ,
• cephalgia
• mbelata nke ịba ọbara,
• ya na njikwa mkpirikpi ngwa ngwa - njigide ma ọ bụ njide iku ume, mgbali intracranial dị elu, diplopia - ọhụhụ anya nke anya abụọ na - apụta na anya, akwara afọ, ọbara ọgbụgba, dị ka platelet, na-asọpụta nke elu nke dermis, na-ebelata mucous membranes.

Atụmatụ eji

Nri na - eme ka o sie ike ịbụ ọgwụ. Ohere iji thioctic acid n'oge afọ ime dabere na uru dịịrị ụmụ nwanyị na ihe ize ndụ dịịrị nwa amụrụ. Na mkpokọta, mmetụta ọgwụ the nwere na nwa ebu n'afọ emebeghị ka FDA guzobere.

Site na ịdepụta thioctic acid, dọkịta na-achịkwa usoro ọbara, karịsịa na ndị ọrịa nwere ọrịa shuga. N'oge usoro ọgwụgwọ, a na-ewepụ mmanya na-aba n'anya.

Na-echekwa mbadamba na okpomọkụ nke + 25 Celsius C, na-echebe site na ikpughe ọkụ anyanwụ na mmiri. Ewezuga ikike nke umuaka n’echeghi ogwu.

Mmekọrịta na ọgwụ ndị ọzọ

Thioctic acid na-akpakọrịta na ọgwụ ụfọdụ, nke nwere ike imetụta nsonaazụ ọgwụgwọ. A hụrụ ihe ndị na-esonụ

• Ọgwụ a na - akwalite akụrụngwa nke ịbelata ọgwụ shuga dị ala n’otu ụzọ ahụkwa si emetụta insulin. Nke a chọrọ nlezianya nhọrọ nke usoro nke ngwaahịa hypoglycemic.
• Ngwọta nke thioctic acid na-ebelata arụmọrụ nke cisplatin, nke a na-eji agwọ ọrịa cancer.
• A machibidoro ụdị ụdị mmiri ahụ maka iji otu oge, na-edozi, dextrose, ọgwụ na-emekọrịta na disulfide na SH-otu.
• Ngme ka njiri ihe mgbochi nke glucocorticoids.
• Mmanya Ethyl na-ebelata ihe ọgwụ a na-a .ụ.

Dodoụbiga ya ókè

Do Overụbiga mmanya ókè na-eme ugboro ugboro. Nke a bụ n'ihi eziokwu ahụ bụ na a na - ekpopụ acid na - esite na nri ngwa ngwa, na - enweghị oge imerụ anụ ahụ. N'agbanyeghị nke a, n'ime ndị ọrịa ị useụ ọgwụ ogologo oge, iji ọgwụ doses karịa ka egosipụtara, ọnọdụ ahụ kara njọ. Mkpesa ndị a na-ebilite:

• hyperacidity nke gastric ihe ọ juiceụ ,ụ,
• obi mgbawa
• mgbu n’olulu afọ
• isi ọwụwa.

Costgwọ nke thioctic acid na-adabere na onye nrụpụta na ụdị ntọhapụ nke ọgwụ ahụ. Ahịa ndị na-esote:

• ihe ngwọta maka nchịkwa intravenous (5 ampoules, 600 mg) - 780 rubles.,
• itinye uche na nkwadebe maka edozi (30 mg, 10 ampoules) - 419 rub.,
• mbadamba 12 mg, 50 PC. - si 31 rub.,
• Mbadamba 25 mg, 50 PC. - site na 53 rubles.,
• Mpempe 600 mg, 30 PC. - 702 ite.

N'ime ụlọ ọrụ na-ere ọgwụ, ọgwụ ndị nwere nnukwu thioctic acid dị n'okpuru aha ndị a:

• ihe emere na Espa-Lipon (Esparma, Germany),
• ihe omume na ampoules Berlition 300 (Berlin-Chemie AG / Menarini, Germany),
• mbadamba ihe mkpuchi, oktolipen infusion concentrated (Pharmstandard, Russia),
• Mbadamba Tiogamma (Woerwag Pharma, Germany),
• mbadamba Thioctacid BV (Meda Pharma, Germany),
• Mbadamba Tiolipon (Biosynthesis, Russia),
• Oktolipen capsules (Onye na-ere ọgwụ, Russia),
• mbadamba, ihe ngwọta na Tielept ampoules (Canonpharma, Russia)

Ọ bụ naanị dọkịta ka ana-ahọrọ analogues dị oke ọnụ ma ọ bụ nke dị ọnụ ala.

Ọtụtụ achọpụtala mmetụta nke thioctic acid n'ahụ onwe ha. Omume maka ngwaọrụ ahụ dị iche. Usersfọdụ ndị ọrụ hụrụ na ọ bara uru, ndị ọzọ na-ekwu na ọ nweghị nsonaazụ.

A na-enye ọgwụ Thioctic acid n'ụlọ ahịa ọgwụ na-enweghị ndenye ọgwụ. Mana a naghị atụ aro ka ha jiri ọgwụ ahụ n'onwe ha, karịsịa na ụmụaka. Ọ bụrụ na mgbaama putara nke yiri nke ahụ edere ọgwụ ahụ, buru ụzọ kpọọ dọkịta iji chọpụta ihe kpatara nsogbu ahụ. Ma ọ bụ naanị mgbe nyochachara nke ọma, ọkachamara ahụ depụtara Thioctic acid. Ntuziaka maka ojiji, nke enyere ebe a, ka enyere maka ịmara onye ọ bụla na ọgwụ ahụ.

A na-ahụkwa vitamin N n’ime nri, ebe ọ ka dị mma inweta ya. Ndị ọkachamara n'ihe banyere nri na-atụ aro iri unere, ọka, apụl, eyịm, mmiri ara ehi, ahịhịa, àkwá. Ọnụego ọgwụ thioctic acid kwa ụbọchị maka onye okenye sitere na 25 ruo 50 mg. N'ime ụmụ nwanyị dị ime na ndị na-enye nwa ara, mkpa ọ dị na-abawanye, wee ruo 75 mg.

Nyocha ndị dọkịta banyere ọgwụ thioctic acid

Ọgwụ ahụ na-adọrọ mmasị na usoro nke akpọtụrụ antioxidant Njirimara. Ejiri m spam n’etiti ndị ọrịa nwere amụghị nwoke maka ịlụ ọgụ mgbarụ akwara, bụ nke ndị theorist na-elebara anya ugbu a. Ngosipụta nke thioctic acid bụ otu ihe - polyneuropathy na-arịa ọrịa shuga, mana ntuziaka ahụ na-ekwupụta n'ụzọ doro anya na "nke a abụghị ihe mere iji eleda mkpa nke thioctic acid na omume ụlọ ọgwụ."

Site n'iji ya ruo ogologo oge, ọ nwere ike ịgbanwe ụtọ uto, belata agụụ, thrombocytopenia ga-ekwe omume.

Mmepe nke ọgwụ antioxidant bụ nke nwere mmasị dị ukwuu maka ọgwụgwọ na ọgwụgwọ nke ọtụtụ ọrịa nke spinal urogenital.

Ọkpụkpọ neuroprotector zuru ụwa ọnụ nke nwere antioxidant, ndị ọrịa nwere ọrịa mellitus oge niile, yana ndị ọrịa nwere polyneuropathies.

Ọnụahịa ahụ kwesịrị ịdị ntakịrị ala.

Na mkpokọta, ezigbo ọgwụ ọgwụ akpọrọ antioxidant Njirimara. Ana m akwado maka iji ya rụọ ọrụ ọgwụgwọ.

M na-eji usoro ọgwụgwọ dị mgbagwoju anya nke ndị ọrịa nwere ọrịa ụkwụ na-arịa ọrịa shuga, ụdị neuro-ischemic. Iji ya mgbe niile na-enye nsonaazụ dị mma.

A gwaghị ụfọdụ ndị ọrịa banyere mkpa ịgwọ ọgwụ a.

Ndị ọrịa nwere ọrịa shuga kwesịrị ịnara ọgwụgwọ opekampe ugboro abụọ n'afọ.

Nnukwu nnabata dị mma na nsonaazụ ngwa ngwa mgbe ejiri ya intraven.

Ihe a kwụsiri ike, na-agbanwe ngwa ngwa n'okpuru ike nke ọkụ, yabụ mgbe a na-achịkwa ya n'ime intraven, ọ dị mkpa ka ọ kechie karama ngwọta ahụ na foil.

A na-eji Lipoic acid (akwadoro nke thiogamma, thioctacid, berlition, octolipene) iji gbochie ma gwọọ nsogbu nke ọrịa shuga mellitus, karịchaa, polyneuropathy na-arịa ọrịa shuga. Na polyneuropathies ndị ọzọ (aholicụrụma, na-egbu egbu) na-enyekwa mmetụta dị mma.

Nyocha nyocha Ndidi na Thioctic Acid

Edepụtara ọgwụ a ka m belata ibu n’arụ, ha nyere m ọgwụ ọnụọgụ nke 300 mg ugboro atọ kwa ụbọchị, mgbe ọnwa atọ m jiri ọgwụ a mee ezughị oke m, ụbọchị m dị oke mfe ịnagide, ntutu m kwụsịrị ịdapụta, mana ibu m anaghị agagharị, na nke a bụ n'agbanyeghị nrube isi na CBJU. Nkwa ahụ ọ na-ekwe nkwa na ọ ga-eme ka metabolism nke nkwa a ghara isi ike. Ọzọkwa, n'oge a na-eji ọgwụ a, mmamịrị nwere isi na-enweghị isi, ma ọ bụ amonia, ma ọ bụ ihe doro anya. Ọgwụ ahụ gwụrụ.

Nnukwu antioxidant. Ego adighi onu ma dikwa ire. Nwere ike were obere oge n’enwezighi ihe ọjọọ.

Enyere m ọgwụ thioctic acid ma m were mbadamba mbadamba 1 n'otu oge kwa ọnwa maka ọnwa 2. Enwere m ike siri ike na ọgwụ a na mmetụta ụtọ m na-apụ n'anya.

Thioctic acid ma ọ bụ aha ọzọ bụ lipoic acid. Emere m ọgwụ abụọ a iji gwọọ ọgwụ a - ihe ọmụmụ mbụ nke ọnwa 2 na oge opupu ihe ubi, mgbe ọnwa abụọ gachara, kwa ọnwa nke abụọ. Mgbe ụzọ izizi nke mbụ gasịrị, ntachi obi nke anụ ahụ na-ahụwanye mma (dịka ọmụmaatụ, tupu ụzọ m ga - eme ihe dịka squats 10 na-enweghị ume mkpụmkpụ, mgbe ọ gbasịrị 1 ọ bụ 20-25). Agụụ na-agbadata ntakịrị ntakịrị n'ihi nke a, ịdị arọ sitere na 120 ruo 110 n'arọ n'ime ọnwa atọ. Ihu ahụ bịara chawa acha karịa, ashen ahụ na-apụ n'anya. Aụrụ m mbadamba mbadamba 2 ugboro anọ kwa ụbọchị n’usoro nke oge niile (site na 8 elekere anọ ọ bụla n’ime awa anọ).

Nkọwapụta dị mkpirikpi

Thioctic acid bụ ihe nnọchianya nke metabolic na-edozi metabolism nke carbohydrates na abụba. Ntuziaka maka iji ọgwụ a na-enye otu ngosipụta - polyneuropathy na-arịa ọrịa shuga. Agbanyeghị, nke a abụghị ihe mere anyị ga-eji lelee mkpa nke thioctic acid na omume ụlọọgwụ. Ihe antioxidant a endogenous nwere ikike dị ịtụnanya iji kee ihe na-emerụ ahụ na-adịghị mma. Thioctic acid na-ekere òkè na cellular metabolism, na-arụ ọrụ nke coenzyme na usoro nke mgbanwe metabolic nke ihe antitoxic na-echebe mkpụrụ ndụ site na radicals n'efu. Thioctic acid na-eme ka insulin na-arụ ọrụ, nke a na-esonyere na ịgbalite usoro iji tinye glucose.

Ọrịa kpatara ọrịa endocrine-metabolic anọwo na mpaghara nlebara anya pụrụ iche nke ndị dọkịta kemgbe ihe karịrị otu narị afọ. Na njedebe nke 80s nke narị afọ gara aga, e bu ụzọ tinye ọgwụ bụ́ “insulin resistance syndrome” na ọgwụ, nke jikọtara, n’ezie, iguzogide insulin, nnabata glucose, mụbara cholesterol “ọjọọ”, belata ọkwa nke “ezigbo” cholesterol, na oke ibu. na ọbara mgbali elu. Ọrịa insulin na-eguzogide ọgwụ nwere aha yiri ya "metabolic syndrome". N’aka nke ọzọ, ndị ụlọ ọgwụ ewepụtawo ntọala nke usoro ọgwụgwọ metabolic ezubere iji dozie ma ọ bụ dozigharị mkpụrụ ndụ, ọrụ ya dị mkpa nke ahụ, nke bụ ọnọdụ maka arụ ọrụ niile na-arụ ọrụ. Usoro ọgwụgwọ metabolic gụnyere ọgwụgwọ ọgwụ homonụ, ijigide ọkwa nkịtị nke chole- na ergocalciferol (vitamin D otu), yana ịgwọ ya na asịd dị mkpa, gụnyere alpha lipoic ma ọ bụ thioctic. N'akụkụ a, ọ bụ ihe na-ezighi ezi ịtụle ọgwụgwọ antioxidant na thioctic acid naanị na ọnọdụ nke ọgwụgwọ neuropathy mamịrị.

Dị ka ị pụrụ ịhụ, ọgwụ a bụkwa ihe dị mkpa maka ọgwụgwọ metabolic. Na mbu, ana akpọ thioctic acid “Vitamin N”, na-ekwupụta ịdị mkpa ya maka sistem ụjọ. Kaosinadị, n’ụdị kemịkalụ ya, ogige a abụghị vitamin. Ọ bụrụ na i banyeghị na mmiri "osisi ọhịa" site na mkpokọta ogige dehydrogenase na okirikiri nke Krebs, ekwesịrị ịkọwapụta nkwupụta antioxidant nke thioctic acid, yana ntinye ya na nrụgharị ọgwụ antioxidants ndị ọzọ, dịka ọmụmaatụ, vitamin E, coenzyme Q10 na glutathione. Ọzọkwa: thioctic acid bụ ihe kachasị dị mma na antioxidants niile, ọ dịkwa mwute ikwu na enweghị echiche dị ugbu a nke uru ọgwụgwọ ọgwụgwọ yana enweghị ntakịrị echiche nke iji ya, bụ nke amachibidogoro, dị ka anyị kwurula, maka neuropathy mamịrị. Neuropathy bụ nkwarụ na-emebi emebi nke akwara anụ ahụ, na-eduga n'ọgba aghara nke etiti, akụkụ na sistemụ okpokoro akwara na imebi akụkụ ahụ na sistem dị iche iche. A na-emetụta anụ ahụ niile, tinyere na ndị nnabata. A na - ejikọ pathogenesis nke neuropathy na usoro abụọ: nrụgide metabolism ike na nrụgide oxidative. Nyere "tropism" nke ikpeazụ nye anụ ahụ ụjọ, ọrụ onye na-ahụ maka ụlọ ọgwụ na-agụnye ọ bụghị naanị nyocha nke ọma nke ihe ịrịba ama nke neuropathy, kamakwa ọgwụgwọ ya na thioctic acid. Ebe ọ bụ na ọgwụgwọ (kama, ọbụna mgbochi) nke neuropathy kachasị dị irè ọbụna tupu mmalite nke mgbaàmà nke ọrịa ahụ, ọ dị mkpa ịmalite ịmalite ọgwụ thioctic acid ozugbo enwere ike.

Thioctic acid dị na mbadamba nkume. Otu ụzọ ọgwụ ahụ bụ 600 mg. N'iburu na nje insioctic acid nwere insulin, n'iji ọgwụ abụọ a na-emekọ ihe, enwere ike ịbawanye ike na hypoglycemic mmetụta nke insulin na mbadamba hypoglycemic.

Mpempe mwepụta

Mbadamba mbadamba, nke ihe nkiri na-acha odo odo na odo na-acha akwụkwọ ndụ na agba, gbara okirikiri, biconvex, na agbaji isi bụ site na odo na odo.

Ndị pụrụ iche: microcrystalline cellulose 165 mg, lactose monohydrate 60 mg, croscarmellose sodium 24 mg, povidone K-25 21 mg, colloidal silicon dioxide 18 mg, magnesium stearate 12 mg.

Ngwakọta nke akpụkpọ ahụ ihe nkiri: hypromellose 5 mg, hyprolose 3.55 mg, macrogol-4000 2.1 mg, titanium dioxide 4.25 mg, quinoline odo na-acha 0.1 mg.

10 PC. - ngwugwu ọnya (aluminom / PVC) (1) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu ọnya (aluminom / PVC) (2) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu ọnya (aluminom / PVC) (3) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu ọnya (aluminom / PVC) (4) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu ọnya (aluminom / PVC) (5) - ngwugwu nke kaadiboodu.
10 PC. - ngwugwu ọnya (aluminom / PVC) (10) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (1) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (2) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (3) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (4) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (5) - ngwugwu nke kaadiboodu.
20 nkp. - ngwugwu ọnya (aluminom / PVC) (10) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (1) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (2) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (3) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (4) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (5) - ngwugwu nke kaadiboodu.
30 PC - ngwugwu ọnya (aluminom / PVC) (10) - ngwugwu nke kaadiboodu.
10 PC. - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.
20 nkp. - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.
30 PC - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.
40 pcs. - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.
50 PC. - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.
100 pcs - polymer Mkpọ (1) - ngwugwu nke kaadiboodu.

Mgbe etinyere ya n’onu, otu uzo bu 600 mg.

A na-etinye n'ime / abanye na mmiri (nwayọ nwayọ ma ọ bụ ntapu mmiri) 300-600 mg / ụbọchị.

Nsonaazụ

Mgbe nchịkwa iv, diplopia, nkwarụ, ọnya ọbara dị na akpụkpọ ahụ mucous na akpụkpọ anụ, platelet dysfunction ga-ekwe omume, na nchịkwa ngwa ngwa - mmụba na nrụgide intracranial.

Mgbe ejiri ha mee ihe, akara ngosi dyspeptik nwere ike (gụnyere ọgbụgbọ, ọgbụgbọ, obi mgbawa).

Mgbe ejiri ya n ’okwu ọnụ ma ọ bụ iv, mmeghachi omume nfụkasị (urticaria, anaphylactic shock), hypoglycemia.